association	dataset	threshold value	standardized value
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.25552
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.06116
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12079334-ADVS-12-2501734-s002.pdf-187-ENSG00000196605_ZNF846	Rummagene Transcription Factor Associations 2026	1.0	null
WholeBlood	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.25437
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RIMS2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.028
Perturb_7755_KD_NOLC1_SRP316009	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.72706
BRD-K21610715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49961
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21838437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42058
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.87466
LY-294002-501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.02716
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5382
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Secretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.559
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5661
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orphenadrine-2318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Bronchioalveolar carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.96
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56954
Mon1-Ccz1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.117
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of cellular localization	GO Biological Process Annotations 2015	1.0	null
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03953354	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27586
BRD-K43936610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20294
Perturb_7907_KD_ZIP11_SRP363583	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_1689_KO_Rptor_SRP101878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57926
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4638-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NOMO1	CCLE Cell Line Gene Expression Profiles	1.0	1.5996
flumetasone-3410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05427
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K91645615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22285
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88653
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.420428
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24282
Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38493972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97085
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6172027-elife-38795-fig2-data2.xlsx-XBP1_RNASeq_only-Gene_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHA15_KO_GDS4341_145_mouse_pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959276
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832567
secretory vesicle	GO Cellular Component Annotations 2023	1.0	null
Perturb_7197_KD_AFF4_SRP164752	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918438
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6416
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.03985
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.773296
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43739
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05901
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CAMA1	CCLE Cell Line Gene Expression Profiles	1.0	1.46244
BRD-K93040255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54347
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
probucol-5261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2141
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19040732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25241
Petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
icSARS-Cov_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.48561
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18202
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47113219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25559
BRD-K50140257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61112
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.903518
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09131
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.46146
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.31327
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43292
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999195
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35539
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.872404
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dl-alpha tocopherol-3256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE95077_5_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148175
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14375485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60061
ERBB2_knockdown_235_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.9691
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3678
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.08627
Specific granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
bufexamac-7413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96502
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4856
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973641
encoding	GeneRIF Biological Term Annotations	1.0	null
diclofenac-333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PC3	DepMap CRISPR Gene Dependency	1.0	2.93297
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20284960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27773
Labial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
establishment of localization	GO Biological Process Annotations 2015	1.0	null
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.5122
BRD-K07602825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02036
Lung adenocarcinoma_LUAD_TCGA-86-7714-01A-12R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28366
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35991
CRCGN011_HEPG2_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05085
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dosulepin-2864	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_100_KD_Pabpn1_SRP318863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.66086
critical	GeneRIF Biological Term Annotations	1.0	null
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11955568-41467_2025_57429_MOESM9_ESM.xlsx-Data_S7-JUN_OIS_Martinez2020_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
STLK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.597
SNU-81	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.11397
hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287447
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859474
BRD-K01853144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06784
BRD-K19045069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3064
apomorphine-6683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86495
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03577
BRD-K04257723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11854
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of secretion	GO Biological Process Annotations 2015	1.0	null
GSE254526,GSE254528_0_v_1_phf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bone resorption	GO Biological Process Annotations 2023	1.0	null
Salivary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.2789
spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.255834
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489838
BRD-A69950438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98206
Acute Myeloid Leukemia_LAML_TCGA-AB-2884-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.026
PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125004
CRCGN008_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1768
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.831031
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11613
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907971
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28598
CRCGN014_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30365
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17408
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4306	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07822
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4U-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein localization to plasma membrane	GO Biological Process Annotations 2015	1.0	null
PC-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.475
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein localization	GO Biological Process Annotations 2015	1.0	null
GSE180200,GSE180201_12_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6170_KD_PROX1_SRP073100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.56943
GSE246053_4_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15863
subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.668126
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
bone resorption	GO Biological Process Annotations 2025	1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24014
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33194
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
azurophil granule	GO Cellular Component Annotations 2023	1.0	null
NCIH1975	DepMap CRISPR Gene Dependency	1.0	2.81533
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
zymogen granule	GO Cellular Component Annotations 2015	1.0	null
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.884
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48385
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04251
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
secretion by cell	GO Biological Process Annotations 2015	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4454399-cas0105-1384-sd1.pdf-55-PURB_PURB	Rummagene Transcription Factor Associations 2026	1.0	null
goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362273
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.831171
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.057922
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
oil secretion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306444
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922736
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0775
BFTC905	CCLE Cell Line Gene CNV Profiles	1.0	1.79611
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899282
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.5789
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62718031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8147
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852852
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868045
cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.128918
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21713052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12914
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25418
BRD-K86988191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43787
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_PFI-1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0109158
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11338_KD_Ankrd35_SRP214047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
sulfamonomethoxine-3484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14873
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4532
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.715014
testis_7e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.866848
SYO1	DepMap CRISPR Gene Dependency	1.0	2.79217
U-138MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77977
BRD-K19580273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73943
BRD-K56437119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42513
EP300	ENCODE Transcription Factor Targets	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34963
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07894
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43616
esophageal varix	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09797
Pulvinus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70608
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80195
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33218
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142684_3_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1910	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K88357881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34821
synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.434591
UMUC16	DepMap CRISPR Gene Dependency	1.0	5.39061
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390799
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52437
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49506
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064668
GSE207787_3_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69657
rolitetracycline-3031	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07011015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01544
MCF7_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141589
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.857153
astemizole-2211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHUEM1	CCLE Cell Line Gene Expression Profiles	1.0	2.36184
TAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84805
trihexyphenidyl-4133	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34429
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5474-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gtpase binding	GO Molecular Function Annotations 2015	1.0	null
Chromaffin granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.88669
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43262
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16611
BRD-K06577881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3861
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876775
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76374
positive regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33833
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02535
benzonatate-5435	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1693_KD_Spi1_SRP280028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
STOCK1N-35215-6422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-874	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_135_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01016
hsa-miR-125a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614974
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37908
atovaquone-2480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.24424
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
BRD-K73706189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6122
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.0665
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17575
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A98099470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41616
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.895067
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1822
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.24333
myosin V binding	GO Molecular Function Annotations 2025	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.61613
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45787
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
PMC10896338-media-3.xlsx-GSEQ_TF_AP1_UP_DOWN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
TE125T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.49458
BRD-K33897007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76162
Flag leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.689559
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876465
MCF7_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144397
chorioamnionitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.225229
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.92569
skeletal muscle cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069401
Perturb_9703_KO_Mef2a_ERP122655	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.2393
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12942
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69231
PMC6026875-MOL2-12-1104-s002.xlsx-List_of_Cancer_Associated_Molec-Tet-MIST1_Cancer_Molecules_BHLHA15	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1909	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
regulation of regulated secretory pathway	GO Biological Process Annotations 2023	1.0	null
Salivary gland epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03746
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12633
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1275	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K62219570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27017
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977389
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219485
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57909
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88636226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03967
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048836
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.298084
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.43602
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
peptidyl-cysteine modification	GO Biological Process Annotations 2015	1.0	null
PLX-4720	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.45
ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.27347
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24952
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.459789
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876775
BRD-K24108193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20416
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary Sj繹gren'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06619
LK-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55064
Prostate adenocarcinoma_PRAD_TCGA-KK-A8ID-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
atractyloside-4717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K36882679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04158
JUND	ENCODE Transcription Factor Targets	1.0	null
12446012-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839404
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84522
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADCY6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09001
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1135
betamethasone-valerate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70549
BRD-K80779045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53592
YMB1	CCLE Cell Line Gene Expression Profiles	1.0	1.85266
Perturb_5846_OE_Klf12_SRP304470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.63056
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27239
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.749579
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12842
methylation	GO Biological Process Annotations 2015	1.0	null
toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279367
MDA-MB-175-VII	GDSC Cell Line Gene Expression Profiles	1.0	2.4135
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.121225
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9317
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43654313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17024
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44873
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
BRD-K44287054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04742
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876775
HSF1_KD_GDS1733_750_human_HeLa cells - 0 Hour	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
t47d	HPA Cell Line Gene Expression Profiles	1.0	0.976154
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-KLF10_KLF10	Rummagene Transcription Factor Associations 2026	1.0	null
myosin binding	GO Molecular Function Annotations 2025	1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16575
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56168
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
processing	GeneRIF Biological Term Annotations	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49448
GSE226285_2_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42605555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22106
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196861
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175188
PHA-00767505E-6545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STAT1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923954
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25795
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.2202
NCIH647	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57752
bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415434
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-30a	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
Sarcoma_SARC_TCGA-IE-A4EK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91824
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.21279
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	1.54095
BRD-K42976515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.184
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.748
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34565
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63063
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482428
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2463
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.283
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.633
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00598
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32627
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39449072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48154
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.326646
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.94995
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00789
BRCA1	ENCODE Transcription Factor Targets	1.0	null
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20049
hsa-miR-125a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.26856
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200352_10_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular protein transport	GO Biological Process Annotations 2015	1.0	null
BRD-K04928505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42033
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14978
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-331-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.8942
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46782
Melanotroph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
physiology	GeneRIF Biological Term Annotations	1.0	null
toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172504
single-organism localization	GO Biological Process Annotations 2015	1.0	null
PMC7610439-EMS118016-supplement-Supplementary_Tables.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987371
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.828043
BRD-K60918542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04891
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36321
Lung adenocarcinoma_LUAD_TCGA-55-6986-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dry eye syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163523
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14278
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89967940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8683
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
memantine-4135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bodies	GeneRIF Biological Term Annotations	1.0	null
amphotericin B-5404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.549
MAX	ENCODE Transcription Factor Targets	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558457
DCAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18854
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9362915-pone.0272017.s004.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.10425
BRD-K00423214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11014
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1694_KD_Spi1_SRP280028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83605
deferoxamine-3936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22145
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.63589
abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239307
Submandibular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
MTA3	ENCODE Transcription Factor Targets	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833045
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93602
BRD-K56188606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17459
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
BRD-K26018295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1207
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329727
protein localization to membrane	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09671
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1728
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02435
GSE190384,GSE190386_2_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rab3d	GeneRIF Biological Term Annotations	1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.968688
prostate	HPA Tissue Protein Expression Profiles	1.0	1.13754
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G8-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41307047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62468
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.51469
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71591
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A2058	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34541
OVCAR5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23422
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.153946
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31988
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_3161_OE_Epac1/Pln_SRP053223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.48495
tamoxifen-143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31808
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.883
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.14787
cinchonidine-2772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10020087-41388_2023_2602_MOESM3_ESM.xlsx-MDAMB231_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2537_KD_MED12_SRP174618	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68091
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54306
azlocillin-3468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K04712840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44289
15793299-TableC	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39372
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063432
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866955
PMC6089851__F1	PFOCR Pathway Figure Associations 2023	1.0	null
nefopam-3627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A04258855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55313
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8664-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47285
BRD-K56776985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67649
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ROCK_INHIBITION_GDS3944_463_mouse_Forebrain astrocytes - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03737
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Protein body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
BRD-K53619784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48092
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07814
BRD-K57498440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0506
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16927
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Entinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016064
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5741
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18666
Hepatitis	CTD Gene-Disease Associations	1.0	1.10388
Clara cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
tiletamine-6013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NACC1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996259
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.62589
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584022
H3K36me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MELK_knockdown_150_GSE32873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.12069
17724462-TableS1	GeneSigDB Published Gene Signatures	1.0	null
JP-4-043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0142
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LASV_FML29 _4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60985
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.238837
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76487707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02872
altretamine-5688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_5204_KO_Rara/Rarb/Rarg_SRP136599	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175466
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-199b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
YANK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37108
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69876
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.809817
terminal bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334498
apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.31596
r1 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95384
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04187
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
troglitazone-6991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.8137
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Barasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013112
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.970645
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85719
MCF7_Entacapone_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0237881
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78519
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4256
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30755
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.525
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598871
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.229
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43484
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56962
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35745
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.762
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927946
BRD-K84690141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09038
697	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48419
MCF7_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145497
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44205
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.42617
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885011
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
valproic acid-6999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04393
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4453	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Basophilic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Sirtinol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0228785
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4704
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A72E-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prestwick-1080-3878	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.741703
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	1.0	2.23062
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04996
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-S7_Data_List_of_all_genes_that_were_upregulated_in_HEK293DAX_cells_for_XBP1s_ATF6_vs_Basal_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
MDAPCA2B	CCLE Cell Line Gene Expression Profiles	1.0	1.3535
Lacrimal apparatus disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.97
Apocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392309
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32043
BRD-K13488816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34266
secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2461
COLO320	DepMap CRISPR Gene Dependency	1.0	2.69544
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07073
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
citalopram-3820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12052
exocrine acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44218
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857301
BRD-A76899420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43937
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155623
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12081
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
l243	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015419
salbutamol-4700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988018
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.514493
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
esophagus squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.275445
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CCNO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45481
Lung adenocarcinoma_LUAD_TCGA-55-6543-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49687
hsa-miR-30d	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871292
hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.517649
GSE149854_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1805
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47579
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38116
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32875
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.637594
hsa-miR-185	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE210662_3_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
CD1C+_B dendritic cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.745477
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.64338
BRD-K11247495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63111
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41428
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903486
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Table_S1_Lists_of_translational_targets_of_MYC_in_MYC_ON_vs_MYC_OFF_P493_cells_and_their_5_UTR_sequences_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67681
MCF7_WP1066_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218343
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24093
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
niridazole-5682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.861057
Zymogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.455
MCF7_Tanespimycin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107473
endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391931
regulation of vesicle-mediated transport	GO Biological Process Annotations 2023	1.0	null
BRD-K54143708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18516
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.90173
BRD-K69834831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45325
secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
cefepime-6237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYB	ChEA Transcription Factor Targets	1.0	null
F0447-0125-6401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.21402
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41411
Metabolism of proteins	Reactome Pathways 2024	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53438
BRD-K90480740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11299
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46407
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901061
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35683
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.57981
BRD-K39460811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50066
leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.618268
GSE89569_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03665
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.19113
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056387
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4209
BRD-K64091938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54947
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906842
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938554
PMC3899188__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904383
BRD-K52881132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19617
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.394
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0044
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.0934
PMC9362915-pone.0272017.s003.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
quipazine-2782	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4QS-1026-SM-3NMCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898439
MCF7_Rigosertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157513
GSE146253_0_v_2_stat4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
maintenance	GeneRIF Biological Term Annotations	1.0	null
u251mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.32491
CTNNB1-20615089-FETAL-BRAIN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.917351
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-intersection_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29594
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856773
pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418099
BRD-K72531838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00844
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9467
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28914
BRD-K36320220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98716
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5205
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
b-50 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887022
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
bemegride-6668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
(-)-atenolol-6725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
zymogen granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.21686
hsa-miR-125b	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
BRD-A67508925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66183
BRD-K36557327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21249
BRD-K44944875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39633
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K77787814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85025
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.748753
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02853
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43088
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78603273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70323
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0209
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44959
KB-3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
A549_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132639
Clitoral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24596
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.26145
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00119
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831026
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.985844
Fetal Death	CTD Gene-Disease Associations	1.0	1.08231
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4651
microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.190814
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4576
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pericarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.354131
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09665
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875729
Recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.809
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6169_KD_PROX1_SRP073100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.33265
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
establishment of organelle localization	GO Biological Process Annotations 2015	1.0	null
BRD-K05000526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0399
extraorganismal space	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.376586
protein localization to membrane	GO Biological Process Annotations 2023	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0729
PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-CCNE2_related_genes_AND_HNSCC_HNSCC_DDP_NOT_DDR_Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.292079
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13437
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00026
CRCGN017_MCF10A.TP53.M_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46361
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
endoprotease	GeneRIF Biological Term Annotations	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98754
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.6454
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXIII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_breast_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14534
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AP1M2	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.828171
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1267
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.37796
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15679
jugular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250953
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70361
BRD-K36575476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34852
PMC8554124-DataSheet2.XLSX-4-RORA_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51795
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22438
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	1.05807
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52635
BRD-K41656340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0481
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PNU-0230031-3629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04954
Keratoconjunctivitis sicca	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Perturb_1172_KD_CBFB_ERP128097	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-30e	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13050_KD_Gad1_SRP304099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.1737
MCF7_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113828
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01739
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55196
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48649
17023574-TableS1	GeneSigDB Published Gene Signatures	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59682
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09221
BRD-K90863245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38367
Postsynaptic endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
SARS-ddORF6_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.88226
VDR-24763502-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	2.07072
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.353395
weibelpalade	GeneRIF Biological Term Annotations	1.0	null
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61058
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37308886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04778
Microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Aril	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12818
GSE187005_5_v_2_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K78642007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62978
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08458
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34213
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135809
sgs cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545342
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02137
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882594
HA1E	DepMap CRISPR Gene Dependency	1.0	2.91965
Myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
skin	HPA Tissue Gene Expression Profiles	1.0	1.50813
BRD-A68123879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05189
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.24528
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fide	GeneRIF Biological Term Annotations	1.0	null
ECC4	DepMap CRISPR Gene Dependency	1.0	6.0613
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.942
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00975
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46554
tanespimycin-381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48451
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7281
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04723
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.822077
forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.992814
BRD-K65266979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54919
TOLEDO	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79856
golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170629
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventilator-associated lung injury_Lung Tissue_GSE2411	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.89517
mantle zone of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14781
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40191
hsa-miR-544b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
actin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.341907
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08345
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-2600-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acute	GeneRIF Biological Term Annotations	1.0	null
MCF7_Lapatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158144
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_AG-490_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242896
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896335
ketorolac-5988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
vh2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.411
BRD-K47620421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18493
BRD-K57643011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16772
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.107
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
myosin binding	GO Molecular Function Annotations 2023	1.0	null
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE57871_11_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30718
rhein	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35457
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37575
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.894579
BRD-K83185986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27586
Intracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.399
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.53398
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79831
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7373278-pone.0236187.s013.xlsx-MDA231genes_overexpressed_in_AR-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_960_KO_Psmc4_SRP173487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHOS/NP (R-970-5) cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
protein secretion	GO Biological Process Annotations 2015	1.0	null
cytoskeletal protein binding	GO Molecular Function Annotations 2015	1.0	null
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.68188
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.533088
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PCBP1_02_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60931
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.02124
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07344
Mucin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.451
bona	GeneRIF Biological Term Annotations	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1717
GSE178267_2_v_4_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_GCN5_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Mucinous adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
GSE85874_4_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83332
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826469
GSE175787_11_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0906
binding	GO Molecular Function Annotations 2015	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrophosphatase activity	GO Molecular Function Annotations 2015	1.0	null
substantia nigra compacta, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09329
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16041
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25501
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84546
GSE206270_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.955995
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.85497
pc-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.640833
SIG-M5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.235457
GSE195582_2_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234514,GSE234516_1_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98891210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5751
H3K36me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02581
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Monocyte_Fetal kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
Rosette leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.04721
azurophil granule	GO Cellular Component Annotations 2025	1.0	null
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06321
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.23951
NHEK	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.03246
19605494-TableS2	GeneSigDB Published Gene Signatures	1.0	null
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83103
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.36677
BRD-K24864035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23485
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.04109
BRD-K04714488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90524
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-7173-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81372179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06861
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A4AC-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895867
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.597666
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13492
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.66017
BRD-K96788889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11461
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38462
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30083
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06117
Salivary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.396
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16489042-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881932
FAM72A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10578
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.360515
mm96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50432649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17523
BRD-K06492501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4213
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0312
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE178255_2_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.54888
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898999
telmisartan_rattus norvegicus_gpl4135_gse29445	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.991951
pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.842867
tiabendazole-4402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415434
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.35589
BRD-K51849151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60776
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16695
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
MDST8_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	3.9635
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996837
Perturb_15307_Mut|KD_Kras_SRP360531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K30674442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3943
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5112
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56561
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I6-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170855
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27442
TC-YIK	GDSC Cell Line Gene Expression Profiles	1.0	1.4535
MCF7_Mercaptopurine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132347
white adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3976
Azurophil granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K73689413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16484
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.292975
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K32537206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10507
mist1_22510200_pancreas_c57bl6_lof_mouse_gpl6246_gds4341	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.02349
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190186,GSE190188_0_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20556
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9346
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K63957636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47451
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948165
fludrocortisone-2328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-27b	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63572
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03271
Neoplasms	CTD Gene-Disease Associations	1.0	1.2818
histamineinduced	GeneRIF Biological Term Annotations	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72209
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21597
JHH6	CCLE Cell Line Gene Expression Profiles	-1.0	-2.35329
butamben-6093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.85955
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905701
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40154
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.72903
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83575
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90617
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC10842785-NIHMS1948219-supplement-3.xlsx-GATA2_sense_vs_antisense-Gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
WIF-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07532
BRD-K47883435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08624
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Germinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
BRD-K32918816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24478
EOL1	CCLE Cell Line Gene Expression Profiles	1.0	2.06396
restriction	GeneRIF Biological Term Annotations	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.814815
Serous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.139
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.24275
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954291
MDA-MB-231	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.8221
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54005
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62845
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thiocolchicoside-5520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28298
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4251	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875729
GSE212628_6_v_1_mier1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864558
Perturb_14864_KD_ZRSR2_SRP341591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.69118
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881837
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05028
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79985
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875729
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT483	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37258
choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.500761
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11557
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35436
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15034
GSE164463_2_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52225
Bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Isolated growth hormone deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05978
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.01186
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11008696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58431
MCF7_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156435
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.811652
Osteosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.67047
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9672
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.13
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40572
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995884
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.616312
BRD-K43820045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00237
iocetamic acid-3022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39181
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K79734831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00786
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K89040444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33415
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0396
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29129
BRD-K44078665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00616
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K35171408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7023
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05661
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993912
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95010912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4747
Tranilast_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00623567
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05088
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
PMC6288913__F1	PFOCR Pathway Figure Associations 2024	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41477
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32873
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9857	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.11329
duodenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.640833
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79422
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.00066
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17134
MCF7_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154165
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82387
zoxazolamine-5390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uropod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
nefopam-2317	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.84883
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	1.92085
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38746
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1219
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24163
Perturb_15547_KO_Ar_SRP069731	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18492
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.62183
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22563
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04405
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152734,GSE152735_1_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.043
demeclocycline-3604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular protein localization	GO Biological Process Annotations 2015	1.0	null
AtT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.407
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.560114
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chlorzoxazone-7456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-2_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CZC-25146	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
MCF7_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118579
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67586245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.599
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
valproic acid-6181	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11325
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16531_KO_Cdk8/Cdk19_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.24392
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01056
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07975
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.528063
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.79769
KDM5B-21448134-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325552
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
OPM2	CCLE Cell Line Gene Expression Profiles	1.0	1.35002
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893202
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
bendroflumethiazide-3758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07587
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856192
urapidil-6696	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Exocrine acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.303
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.922259
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84693
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.86376
Perturb_14349_KD_CDK12_SRP223931	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE169155_3_v_7_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27038
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.79737
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056434
BRD-K48681121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27324
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.81488
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122391
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909283
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE57871_6_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
reserpine-4203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MZ2-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65747
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09671
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.231672
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160657
MCF7_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249773
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876775
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.992628
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82503
GSE214382,GSE214383_3_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01853
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tobramycin-2481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Bile canaliculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19471
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
hydrochlorothiazide-4970	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1238
5g3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
Vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.623
tiabendazole-2479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol-6200	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59359
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.860314
hyperthyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.351923
BRD-K30792491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42328
gtpases	GeneRIF Biological Term Annotations	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113221,GSE113968_6_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2646_KO_PTPN23_SRP344246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60178
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42455
BE(2)-M17 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05097
GSE149075_3_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982663
LMSU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57055
BRD-K81082554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68111
azurophil granule membrane	GO Cellular Component Annotations 2023	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226285_2_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987295
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.943998
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.991734
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987321
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Osteosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15273739-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
chlortetracycline-1541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957601
Von Willebrand's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
REST	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K89416748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35661
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09591
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7335
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vesicle tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.442
PMC9229595-Table_2.xlsx-LPS_subset_IX-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973717
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7428-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.638404
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.12538
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054744
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23021
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904258
BRD-K44916315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61353
BRD-K43364707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09492
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16238
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05754
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898968
ritodrine-5680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.775664
equilin-5255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
troglitazone-504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18938
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01161
E2F1	ChEA Transcription Factor Targets	1.0	null
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71210410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28356
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052671
GSE134375_3_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42455150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96198
GSE207914_5_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97224540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65157
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904256
pancreas	HPA Tissue Protein Expression Profiles	1.0	1.13754
lymph node	HPA Tissue Gene Expression Profiles	-1.0	-0.849163
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01807
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18005
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.931974
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
consequently	GeneRIF Biological Term Annotations	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92192
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K22679163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10691
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048384
d5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.966
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56496
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.891169
epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.790628
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62185
dorsolateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80318
BRD-K57907671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58732
upper dorsal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10544
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89116
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-GeneID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Adenoma of small intestine_Intestinal Epithelium_GSE422	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.83888
BRD-K40241022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12667
GSE199204,GSE211619_4_v_7_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830255
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979137
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Tacedinaline_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194471
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03328
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08013
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.536229
adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414293
BRD-K67150949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04135
BCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4214
Inflammation	CTD Gene-Disease Associations	1.0	1.89137
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66943
BRD-K48459037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12492
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	2.63052
GSE82032_3_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.10155
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10812
GSE211357_2_v_0_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19597
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5027
BRD-K10494344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9267
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1219
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22346
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12301
Sialadenitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5932012-41467_2018_4180_MOESM18_ESM.xlsx-Table_19-GSEA_Gene_lists-Zuber_Myb_KD_UP_HUMAN_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.181
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76342
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09011
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52366
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878601
oil gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194691
ciliary cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.164542
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574416
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5604
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87004
BRD-K56658444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41069
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705173
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9796
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54603
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84334677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50596
mexiletine-2324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.594
hsa-miR-4308	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Small GTPase superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein modification process	GO Biological Process Annotations 2015	1.0	null
BRD-K38519440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70989
BRD-K46095779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52382
15361855-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.927485
Perturb_10774_KD_Csde1_SRP383422	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.89537
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02361314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01269
trimipramine-3342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.400826
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06004
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875729
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4024
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44909
T-bar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.702
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5229
BRD-K55841827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42002
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
indapamide-2322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.37455
PMC6944231__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Rab-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14834
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bucladesine-842	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52202
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14265_KO_E2f2_SRP090185	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.80958
hsa-miR-30b	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63739
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M1-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08973
NR2F2	ENCODE Transcription Factor Targets	1.0	null
5155877-6544	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_TG101209_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203357
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.953442
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85823016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03973
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3611	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12924
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_2_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_2_Mesendoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K63119190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05921
MCF7_Fasudil_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130234
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hymecromone-5684	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
esculetin-3120	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cytoplasmic microtubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Zileuton_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179492
PMC5287225-supp_gr.209163.116_Supplemental_Table_S4.xlsx-Table_S4-Supplemental_Table_S4_Differentially_expressed_genes_related_to_ZNF384-rearranged_ALL_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22034
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27523
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S12-Table_S12_MR_resluts_of_brain_pQTL_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	1.51435
adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683103
cotinine-5611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07264
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52658
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829221
cefepime-3581	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2171
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856891
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
20559987-TableS1	GeneSigDB Published Gene Signatures	1.0	null
PMC8511144__F7	PFOCR Pathway Figure Associations 2024	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3426
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30262
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93602
thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31187
PHF8	ENCODE Transcription Factor Targets	1.0	null
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14919
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852852
positive regulation of exocytosis	GO Biological Process Annotations 2023	1.0	null
PMC8906867-pbio.3001569.s011.xlsx-All_genes_up_in_HEK_XBP1s_ATF6-Unnamed_1_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847397
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.993294
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10837
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.979262
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
BRD-K24502602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29975
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.965488
pericardium disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.12843
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963519
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	1.0	1.07838
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30051
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pirenperone-5639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.4629
BCB000038-7516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFAP2A	ChEA Transcription Factor Targets	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.45291
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12586
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869756
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNU-0251126-4714	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.59895
regulation of regulated secretory pathway	GO Biological Process Annotations 2025	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hyperprolactinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.356341
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985777
PMC7281309-mmc16.xlsx-Supplementary_Table_14-Supplementary_Table_14_Differentially_expressed_genes_in_H1819_after_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carapace	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.288
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cephalothorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22039
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6467
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.21886
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32686
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
MCF7_Ki8751_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140426
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912782
Choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EF-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43391
MCF7_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187028
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.19251
CEBPB	ENCODE Transcription Factor Targets	1.0	null
golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.272633
E2F4_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
irf8_00000000_splenic_cd11bplusgrdash1_hdash2b_gen_background_lof_mouse_gpl6887_gse39228	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.171118
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Warburg micro syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.846
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.568832
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42537
monensin-3443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K58977196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54696
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876775
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242083,GSE242098_2_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
YH13	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47416
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34083
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.529994
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1505
16-phenyltetranorprostaglandin E2-7541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68237
BRD-K58753007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55642
BRD-K47510632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33922
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.590553
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.04711
BRD-K21285405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27916
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.64236
BRD-K41433616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33431
BRD-K81884810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39584
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1799
SNU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56223
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM16	CCLE Cell Line Gene CNV Profiles	1.0	2.9522
tretinoin-390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism cellular localization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB453	CCLE Cell Line Gene Expression Profiles	1.0	2.03173
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161716
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42715
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.34314
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.02745
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
arecoline-5423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.15232
BRD-K53896147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68631
ATG16L1	Pathway Commons Protein-Protein Interactions	1.0	null
benzthiazide-3329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7884075__F4	PFOCR Pathway Figure Associations 2024	1.0	null
organic substance transport	GO Biological Process Annotations 2015	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.112
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89219
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8052
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Curcumin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143052
clara cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351856
RAB5IF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37801
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40045
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055624
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08034
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-345	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.095324
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44921612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06214
MCF7_Cimetidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189656
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.13518
Perturb_2571_KD_FKBP52_DRP008309	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
16288205-GeneTable3	GeneSigDB Published Gene Signatures	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K02311826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96978
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26282
ChIP_NACC1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19815
endemic goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.608885
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01297
SQ1_LUNG	CCLE Cell Line Proteomics	1.0	12.932
BRD-K51054234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21952
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34425
BRD-K49872883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47199
tanespimycin-432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943234
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16985
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.798811
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92769
BRD-K98969488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11124
MCF7_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177168
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51071
MCF7_Clevudine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156271
RXF393	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
cloperastine-3608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910644
Lung adenocarcinoma_LUAD_TCGA-86-8278-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193806
ZBTB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08438
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.62792
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-4-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36196
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16974
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9152
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15792876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34929
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913391
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82521348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18317
BRD-K59772014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21016
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276145
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23078
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62342
BRD-K58728497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13085
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.498832
PMC5195898-NIHMS825571-supplement-3.xlsx-Sheet1-H1975_M1_vs_H1975_M1_CIC_reconstitution_Differential_gene_expression_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13611
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11694
hsa-miR-1321	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388909
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
establishment of protein localization to extracellular region	GO Biological Process Annotations 2023	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876775
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
ZNF580	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41221
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.912025
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39710695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17426
cinchonine-4107	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47848960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22197
Salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.933
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53157
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151188
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.1403
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Rough endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06035
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04625
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2171
BRD-K45428339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00705
MCF7_SRT3025 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192159
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
Exocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K23286105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02719
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.271533
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072803
BRD-K65423474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09116
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00723
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02198
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991143
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_178_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25097
dinoprostone-6547	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_767_mouse_Skin - 1 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08458
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08893
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18749
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.31355
SNB19	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61635
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68395284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15438
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.38128
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29594
18381418-Table1	GeneSigDB Published Gene Signatures	1.0	null
ctnnb1_21565795_adrenocortical_adenomas_lof_mouse_gpl570_gds3912	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.580741
diethylstilbestrol_rattus norvegicus_gpl1355_aci_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932659
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60558
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07966
GSE57871_6_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
DU145	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.2454
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10168
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34959
MCF7_Vandetanib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113096
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
kinetin-6073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
IGROV1	BioGPS Cell Line Gene Expression Profiles	1.0	1.01406
Perturb_15071_OE_Fezf2_SRP041818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62764
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50830147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0872
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sgs	GeneRIF Biological Term Annotations	1.0	null
Blood	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51516
BRD-K41729242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33386
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12048
BRD-K58113140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44053
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.05799
MCF7_M344_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00956274
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05327
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.756191
Acute Myeloid Leukemia_LAML_TCGA-AB-2985-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04693
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	1.49648
Cortical granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
BRD-K45520793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57054
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12189
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53416
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50953
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71468
vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4292	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
amebiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.425139
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062429
MCF7_Fulvestrant_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181431
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE252857_1_v_3_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.951
lysosomal membrane	GO Cellular Component Annotations 2025	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056323
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7767
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4117
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rosiglitazone-369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.98125
GSE181059_2_v_1_runx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12107215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11351
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0564
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
BRD-K49132774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13323
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059586
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07587
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAR polarity complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
small	GeneRIF Biological Term Annotations	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31684
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068363
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.52437
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Golgi stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18279
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32202
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lung fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330094
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841244
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.514
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851696
vonwillebrand	GeneRIF Biological Term Annotations	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21058
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08863
MCF7_Sorafenib Tosylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138727
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.164
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UH-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46201
trans-golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.447656
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41072
MCF7_UNC0379_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140827
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75095
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068876
SAOS2_BONE	CCLE Cell Line Proteomics	1.0	7.23493
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.301425
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3488
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14781
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62686
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05586628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98275
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173387
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56194
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.019991
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
carteolol-4176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28301
CRCGN017_MCF10A.TP53.M_24H:J11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19847
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67090705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25051
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07498
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2334
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.867
KDM5B	ChEA Transcription Factor Targets	1.0	null
BRD-K56775726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47723
hsa-miR-3065-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
POLR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13149
SNU668	DepMap CRISPR Gene Dependency	1.0	5.8336
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061351
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58088
MAFK	ENCODE Transcription Factor Targets	1.0	null
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0215
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10814
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38356
H3K36me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24235
AG-013608-6400	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1538
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MDAMB361	DepMap CRISPR Gene Dependency	1.0	3.43111
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BLOC-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
BRD-K15833017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90917
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
rescinnamine-4386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00655
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855725
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12833
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05388
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S11-Table_S11_MR_resluts_of_brain_pQTL_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K58944125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36067
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931119
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4644	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
cellular component organization	GO Biological Process Annotations 2015	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab9_KDM5C-KD-down-DKD-rescued-Table_9_Down-regluted_genes_in_KDM5C-KD_and_rescued_genes_in_DKD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NB(TU)1-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
prilocaine-2314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23861
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999932
regulation of exocytosis	GO Biological Process Annotations 2023	1.0	null
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.087
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pentamidine-4396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.118454
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81039
liothyronine-3324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.905548
GSE96544_1_v_0_mebendazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19178
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.93338
FOXP1	ChEA Transcription Factor Targets	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.7832
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.382
GSE140936,GSE140938_2_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01474
Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86722849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02884
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9255_KO_Cftr_SRP067491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.0691
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41736
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0242
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2767
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922996
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20359
pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592845
propofol-3048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3105
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93205
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_7_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.96071
GSE143643,GSE143644_3_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86630280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46661
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29594
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01774461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39002
mantle zone of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34434
SP1	ENCODE Transcription Factor Targets	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02319
hsa-miR-4694-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K54420800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21599
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cell trailing edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.938
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3467	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.57072
Dry eye syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.841
BRD-K40318276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04329
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.291
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249329
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04771555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03284
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung transplant rejection_Trachea_GSE3418	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.34839
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12033
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40026
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.353399
intermediate stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23078
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIM	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52805
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	3.11798
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18604
BRD-K44401972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22127
MCF7_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212958
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093569
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
ioversol-6726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K84821804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25467
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12225
PMC12804025-mmc2.xlsx-LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0724
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40426
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3673
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184563
primary motor cortex (area M1, area 4)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06957
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
bretylium tosilate-3057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01339
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.895
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K96154586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32689
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23615
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32633
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.4551
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Avagacestat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184628
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
Perturb_7427_KD_PTBP1/PTBP2_SRP059242	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.43088
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
interfere	GeneRIF Biological Term Annotations	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
bretylium tosilate-6674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15188108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14957
IRF1	ENCODE Transcription Factor Targets	1.0	null
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.66673
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0176
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
procyclidine-2991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1419	GDSC Cell Line Gene Expression Profiles	1.0	1.96015
plant collar	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65794
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36436
lorglumide-5254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CYP2C9	Pathway Commons Protein-Protein Interactions	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13723
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.40064
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXVII-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_sarcoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
BT483	CCLE Cell Line Gene Expression Profiles	1.0	1.67036
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897031
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5326-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11953091-12035_2025_4695_MOESM1_ESM.xlsx-s5-Supplementary_Table_5_Results_of_the_2-sample_pQTL_MR_on_insomnia_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
sirolimus-7001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850391
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166315_5_v_3_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10027
esophagus	HPA Tissue Gene Expression Profiles	1.0	0.936178
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K58708811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.259
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
phthalylsulfathiazole-3033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.11828
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.33739
establishment of vesicle localization	GO Biological Process Annotations 2015	1.0	null
Vacuolar membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.31783
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995884
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04952
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15536
Small Cell Lung Carcinoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00052
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
PMC8191339-mmc1.xlsx-Table_S3_DE_genes-LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14153
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
transcription	GeneRIF Biological Term Annotations	1.0	null
UM-SCC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
JPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02358
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.14303
basophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395709
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.268332
E2F2_KD_GDS4094_447_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192433
GSE57871_11_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
clopamide-5402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K08075712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09631
Acute Myeloid Leukemia_LAML_TCGA-AB-2969-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07067
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10676
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.663
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32874
protein transport	GO Biological Process Annotations 2023	1.0	null
BRD-A61864215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55256
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52222
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12341
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.511233
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.861931
Breast carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4525
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.07613
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredProteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K25907192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42298
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906939
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890105
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9869
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYB-21317192-ERMYB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC5840266-41598_2018_22384_MOESM13_ESM.xlsx-UBR7_KD_significant-Unnamed_23_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mexiletine-3781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.18155
pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.971119
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18927
metrifonate-5989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K54925224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04372
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25696
HHV8_72Hour-LEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.95935
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.26991
Rectum adenocarcinoma_READ_TCGA-EI-6508-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08384
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11624
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996837
MAST1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934043
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	3.42272
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Q-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ofloxacin-2302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22155
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46859
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8784
MCF7_Entacapone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0234668
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08025
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.909
BRD-K51933590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02495
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.02
regulation of localization	GO Biological Process Annotations 2015	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49775
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82525
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERBB2_knockdown_231_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.0579
skbr3	HPA Cell Line Gene Expression Profiles	1.0	1.25979
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mitochondrion	GO Cellular Component Annotations 2015	1.0	null
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955293
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metolazone-5392	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36799
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_10714_KO_Foxo1_SRP375712	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.21145
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
BRD-K71138333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0318
MCF7_Trametinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211829
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988993
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28502
BRD-K75625428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0428
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20691
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HG-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.25463
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.398
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08999
GSE174701_5_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16837_KO_Sufu/Spop_SRP145845	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0714
myb_16205643_primary_monocytes_gof_human_gpl570_gse2816	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.055266
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
N6-methyladenosine-2626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
newcastle disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.58939
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of exocytosis	GO Biological Process Annotations 2015	1.0	null
Vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04797
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.283
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4648
BRD-K99038919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54242
dexpanthenol-7455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43856
LCLC103H_LUNG	CCLE Cell Line Proteomics	1.0	3.65848
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864538
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.698625
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10824
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3105
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-200a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22266
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_SRT1720 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172251
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11523
MCF7_Tofacitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141055
ELF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_147_KD_Zfp407_SRP051775	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.6215
carbinoxamine-2725	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18992
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50618
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86827
GSE57871_6_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15881
MYC	ChEA Transcription Factor Targets	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0294
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.27084
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7562
infection	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97718
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54009
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40465
hsa-miR-320b	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10888
myosin v binding	GO Molecular Function Annotations 2015	1.0	null
SARS-CoV_12Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51367
vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401007
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01994
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846429
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97732
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348889
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98092
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU1041	DepMap CRISPR Gene Dependency	1.0	2.79315
rab protein signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE252857_1_v_3_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79044
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43438
secretion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169956
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04382
CD276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2349
BRD-K44445002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15105
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K39185798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19618
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
microtubule associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072298
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78707
BRD-K79303560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28569
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
METTL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66985
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Divalproex Sodium_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142201
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24053
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15461
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.706402
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82196
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
MCF7_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221801
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19271
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28828
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PL21	CCLE Cell Line Gene Expression Profiles	1.0	1.88076
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06207
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94624
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23087
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2764
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340757
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09377
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-81-CAMTA1_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50778
POLR3A_01_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61454
Anteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7658
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.727738
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1266
Peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.738713
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87735
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48557
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838207
19036130-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
cephaeline-5612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09444
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0486
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22453
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
cellular process	GO Biological Process Annotations 2015	1.0	null
diethylstilbestrol_mus musculus_gpl81_gse1839	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.29746
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86089
Exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.105
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lysosomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914138
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-ESR1_mutation_E2_Co-Down_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06809
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
BRD-K92468187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47926
fenoprofen-4736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305001
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16428_KD_Atf3_SRP327850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.04077
BRD-K09149805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0996
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10909
single-organism process	GO Biological Process Annotations 2015	1.0	null
synapse part	GO Cellular Component Annotations 2015	1.0	null
GSE85302_0_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64026092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23482
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32949
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_17635_KD_YTHDF2_SRP126652	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
JP8 aviation fuel	CTD Gene-Chemical Interactions	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31386
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01797
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853727
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115363_2_v_0_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0129
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835566
DB	CCLE Cell Line Gene CNV Profiles	1.0	1.54
biological_process	GO Biological Process Annotations 2015	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K84792324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06237
GSE86021_0_v_1_crenolanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.154822
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908131
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055371
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26896
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17836
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67018
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97181
GSE148692,GSE148695_2_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
metaraminol-2298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
preisthmic tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43973
MET_knockout_260_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.30709
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352969
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50304
NB7	DepMap CRISPR Gene Dependency	1.0	2.11334
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22853
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49391
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895361
Sarcoma_SARC_TCGA-HS-A5N7-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.26021
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STOCK1N-35215-6380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855781
Von Willebrand's disease 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
fallopian tube	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein transport	GO Biological Process Annotations 2015	1.0	null
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910644
GRANTA-519	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_17411_KO_Kat7_SRP346205	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.869279
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97839095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12342
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05096
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21028
nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.079265
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151818
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844748
BRD-K59670689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43865
HCC1419	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.25142
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.1556
lacrimal apparatus disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070698
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.811891
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824159
BRD-K74779337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31961
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36644
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36908
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Putamen (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.05726
Perturb_1291_KO_Lef1/Tcf7_SRP111197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
MCF7_Cediranib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159854
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66545
NUGC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-2.25052
NCIH2087	CCLE Cell Line Gene CNV Profiles	-1.0	-2.58169
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129702
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02212
butyl hydroxybenzoate-5245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22065
BRD-K07798964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22925
maturing	GeneRIF Biological Term Annotations	1.0	null
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05827
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.04794
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943952
19605494-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1731
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43262
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39639513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58316
apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.644001
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	1.0	0.92396
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36357
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5241026__F8	PFOCR Pathway Figure Associations 2023	1.0	null
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066387
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09222
icSARA deltaORF6_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.73157
BRD-K59130783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4666
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.02299
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXVI-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_prostate_cancer_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_14674_Mut_GCK_SRP089943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.20305
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.930366
actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.294748
Perturb_16556_KO_Usp39_SRP317794	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.61687
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02017
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46523
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862715
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30092
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64252
BRD-K64827406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43588
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52947
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.575616
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-CO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
mantle zone of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45487
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.980275
BRD-K96209756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29204
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K32520360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04051
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6889
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38153
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551695
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
BRD-K24815102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47915
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02185
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996837
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83809
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13781
periventricular stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80235
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967782
MXI1	ENCODE Transcription Factor Targets	1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	1.0	0.914821
blood	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3863
BRD-K80298486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39437
AKT1	Hub Proteins Protein-Protein Interactions	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19914
hsa-miR-578	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35006
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26055
male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050203
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.7146
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065904
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05607
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2303
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054657
BRD-K64296795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08057
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K77324165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2303
Pontine reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39033
esophageal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.134359
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03966
BRD-K74289419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20801
NELFE	ENCODE Transcription Factor Targets	1.0	null
iopamidol-3473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128695
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05097
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14770_KO_Nfam1_SRP345029	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.20682
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488667
NFE2L2_KO_GDS514_699_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.729385
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6252
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2538
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.72483
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08458
Secretory granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
2,6-dimethylpiperidine-6049	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59442
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828625
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383
BRD-K51572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27753
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-420-BCL6B_BCL6B	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59715
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830411
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39397
proton-transporting V-type ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.033
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0033
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03994
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09587
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0184
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	1.52521
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2444
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27039
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12791
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K68544484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1428
BRD-K54111001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endosperm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXV-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_hepatocellular_carcinoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2378
GSE246195,GSE246305_4_v_3_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.226686
activate	GeneRIF Biological Term Annotations	1.0	null
GSE185519_6_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574017
BRD-K18637162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76232
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045984
16651414-Supp4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K54151058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84004
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
thioperamide-5635	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00256
furin	GeneRIF Biological Term Annotations	1.0	null
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0644
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01621
BRD-K54332342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70234
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38545
MCF7_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.023027
esculin-3052	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K47314501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15643
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997073
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4584
Cotton fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.27846
cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.756191
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17435
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876775
Perturb_12968_KD_DBN1_SRP317929	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung adenocarcinoma_LUAD_TCGA-55-8508-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
oral	GeneRIF Biological Term Annotations	1.0	null
BRD-K59865704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35898
denatonium benzoate-3123	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835002
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Weight Gain	CTD Gene-Disease Associations	1.0	1.69448
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19702
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09250647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24009
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	2.90945
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.40668
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06373
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03998
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178126
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17219
MCF7_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153008
16467094-Table2	GeneSigDB Published Gene Signatures	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06257
probucol-5626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12667
BRD-K01705159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24206
arcaine-4974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-BatSRBD_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.54896
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MMAC	DepMap CRISPR Gene Dependency	1.0	4.1821
SGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.554
BRD-K91624805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0624
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE189859,GSE189861_4_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.24498
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88244
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05088
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28165728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3197
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
methapyrilene-6644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
BRD-K15768601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71833
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K99220724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45595
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16337
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1219
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46073
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.35605
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98225007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3442
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81656074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09257
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.915386
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.273734
Primary lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874747
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407073
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23195
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30042
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9197
BRD-A78085235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82248
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pulmonary Edema	CTD Gene-Disease Associations	1.0	1.31716
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.891373
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6662
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15033
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95614
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883584
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32601
vesicle docking	GO Biological Process Annotations 2015	1.0	null
nr2c2_20864514_liver_1yo_lof_mouse_gpl4134_gse21903	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.024864
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44604
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45315
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NK-92MI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.12906
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053454
BRD-K98301999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73899
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70016
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08119
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59816
BRD-K84788922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02108
BRD-K07414059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09521
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
K562_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191035
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.75883
NCIH838_LUNG	CCLE Cell Line Proteomics	1.0	4.21899
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65545
AKT2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q8-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29458
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952756
BRD-K43390655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59641
PMC8044433-mmc4.xlsx-Sheet1-Acute_LPS_Microglia_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25064302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04006
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58269
brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394953
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	3.17805
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36777
hsa-miR-320d	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
BRD-K62329160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0297
CHM	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.64618
rotenone-5915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.14132
BRD-K23432132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9156
proxyphylline-3115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9858
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936971
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10544
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38835
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00929
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48895
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreas-pancreatic acinar cell	Tabula Sapiens Gene-Cell Associations	1.0	9.42257
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
19305503-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K23203419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42812
OV90	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39094
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55411
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S15-Table_S15_MR_resluts_of_brain_pQTL_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.18
valproic acid-6199	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9229595-Table_2.xlsx-LPS_subset_IX-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
latamoxef-5609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
BRD-K26200435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35036
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230656
MAP3K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07323
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87017
vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tanespimycin-5914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71085
positive regulation of transport	GO Biological Process Annotations 2015	1.0	null
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840313
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07698
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.52987
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22481
15565109-Table2	GeneSigDB Published Gene Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
ketorolac-3110	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
catatg	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4763-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539396
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Malignant peripheral nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919132
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle	GO Cellular Component Annotations 2015	1.0	null
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bursa of fabricius	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.625061
parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06545
ZNF304	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13459
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30821056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32478
MCF7_Busulfan_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147307
Cholangiocarcinoma	CTD Gene-Disease Associations	1.0	1.18981
protein alkylation	GO Biological Process Annotations 2015	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51157416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23808
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02119
medrysone-4727	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.07947
BRD-K44760023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38863
dehydrocholic acid-5681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0316
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49276
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
Microvillus inclusion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.919061
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880822
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31984
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399492
BRD-K73092207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27881
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917247
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932262
MCF7_CEP-33779_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0232222
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
BRD-K79709959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53168
GSE143643,GSE143644_1_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17933
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.49064
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14322
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01288
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27151
clorsulon-2884	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
imatinib-366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Asphyxiating thoracic dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00117
BRD-K37283718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70481
BRD-K57786028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2589
BRD-K42032479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32162
sulfadimethoxine-4724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_2659_KO_USPL1_SRP344246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.57544
CTNNB1-20615089-FETAL_BRAIN-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08634
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.131
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37633
POLR3A	ENCODE Transcription Factor Targets	1.0	null
GSE157594_5_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160996
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42925
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02773
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MDA-MB-175-VII	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.50687
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.087
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K55728478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40867
BRD-K73114074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32894
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071867
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.977096
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.867946
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27328
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02558
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30943
GSE148692,GSE148695_7_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE93309_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41116634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63803
haloperidol-5241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65529782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03517
BRD-K06873288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78118
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31594
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Larynx squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
monobenzone-3054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
atropine methonitrate-3116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062509
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7647
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_11_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18309
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.041
Adrenocortical carcinoma_ACC_TCGA-OR-A5K9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
mast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255567
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88156935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20063
sulfametoxydiazine-2712	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trimethoprim-4701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-125b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
tumor of exocrine pancreas	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.12361
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15146
niflumic acid-2399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.895747
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38116
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.14085
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947498
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02508
BRD-A03668899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78945
MG-63 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.856732
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB3IP	Pathway Commons Protein-Protein Interactions	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
MCF7_PHA-680632_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163338
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.87579
MCF7_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108143
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14589
19458276-Table3	GeneSigDB Published Gene Signatures	1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10652
PLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73913
BRD-K42008693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07185
BRD-K37722313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3697
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
rifabutin-4349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940442
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996321
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_GSK1070916_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155567
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09518
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.15231
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45403
PF-00539758-00-6379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057153
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cefmetazole-2524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skeletal muscle cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
BRD-K42126155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80903
Perturb_1769_OE_miR125a_SRP282869	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.32268
Lung adenocarcinoma_LUAD_TCGA-95-7944-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2568
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.9478
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39643
HCC827	DepMap CRISPR Gene Dependency	1.0	2.67563
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03814
MM485	DepMap CRISPR Gene Dependency	1.0	4.74889
Parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.075
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51516
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6844-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15775306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04626
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12954
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
myc_20940306_e13dot5_erythroblast_purified_from_liver_gof_mouse_gpl6885_gse18558	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.68447
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.445805
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
binds	GeneRIF Biological Term Annotations	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48187
BRD-K74537058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24049
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96814
18231642-TableW1	GeneSigDB Published Gene Signatures	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
valdecoxib-6378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE159049_3_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03916755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01012
BRD-K68084083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35267
nimesulide-7024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MONOMAC6	CCLE Cell Line Gene Expression Profiles	1.0	1.37198
MCF7_Quercetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162915
PMC12703482-AMS-21-5-213605-s2.xlsx-Supplementary_Table_SXIV-SMR_results_of_expression_levels_of_VDR_target_genes_in_peripheral_blood_and_risk_of_melanoma_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5241026__F8	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K30772101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61412
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
MCF7_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127925
fludroxycortide-6039	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10843
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40378743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18479
HDL cholesterol	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.90492
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05409
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.7332
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12808
Final leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.087117
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.14704
hsa-miR-4641	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
MCF7_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107004
superficial stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1805
Small GTP-binding protein domain	InterPro Predicted Protein Domain Annotations	1.0	null
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
impedes	GeneRIF Biological Term Annotations	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17186_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SAYSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1357
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.727
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_435_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.86123
BRD-K43628610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30821
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
Perturb_3245_OE_RUNX3_SRP330291	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.04019
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05617
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31203
Innate Immune System	Reactome Pathways 2024	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06406
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.08515
lacrimal gland acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35995
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1012-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM-159PT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070558
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250301
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
protein localization to cell periphery	GO Biological Process Annotations 2023	1.0	null
SW579	CCLE Cell Line Gene CNV Profiles	1.0	2.06624
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
peptidyl-cysteine methylation	GO Biological Process Annotations 2015	1.0	null
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46654
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16477
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41053
MCF7_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0234194
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68085
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K85232515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45927
CRCGN014_HEPG2_24H:I18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02871
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86466
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14534
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.811652
MCF7_PFI-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189455
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16381
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR3A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45986774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5259
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02218
r1 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33823
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K36me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13653
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_proteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE249893_1_v_0_tfam_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A84816049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3804
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050488
MCF7_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201613
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.749996
E2F4	ENCODE Transcription Factor Targets	1.0	null
Vacuolar proton-transporting V-type ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.218
BRD-K60069390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53576
786-O	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.945097
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
moroxydine-1527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982267
cellular macromolecule localization	GO Biological Process Annotations 2015	1.0	null
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845303
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Supramolecular fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45519
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14405
Childhood Osteosarcoma	DisGeNET Gene-Disease Associations	1.0	null
Podosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.967
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25744
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5094-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.164542
Paneth cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29129
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49712
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
granulocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161425
LCLC-97TM1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.21256
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96509
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6226
cone-rod dystrophy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S14-Table_S14_MR_resluts_of_brain_pQTL_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64457
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.302
amphetamine_rattus norvegicus_gpl6101_gse31081	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
retrorsine-2129	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.226686
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64730221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41314
Melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.675
those	GeneRIF Biological Term Annotations	1.0	null
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
PAX5	ENCODE Transcription Factor Targets	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
plasma membrane organization	GO Biological Process Annotations 2015	1.0	null
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.148
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24103
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU620	DepMap CRISPR Gene Dependency	1.0	2.93581
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESCRT I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.140386
d36	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.55
Chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
indometacin-503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96557
Corneal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dicloxacillin-6666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
haloperidol-2704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907703
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01449
amiloride-1470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Ellagic acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177252
ursodeoxycholic acid-3105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_12991_KD_MAF_SRP276044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.82885
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
sulfamethoxazole-4690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56939159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5558
Weibel-Palade body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.987
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067039
WM3211	DepMap CRISPR Gene Dependency	1.0	3.04618
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50415
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242983
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49069
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328628
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22953
Multivesicular body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Goblet cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Metabolic Syndrome X	DisGeNET Gene-Disease Associations	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04476
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06208
BRD-K77139764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1666
BRD-K78668110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98532
GSE184133,GSE184137_2_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836231
Autosomal recessive osteopetrosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
BRD-K27597444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28546
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080747
Weight Loss	CTD Gene-Disease Associations	1.0	1.84198
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-0.830568
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NACC1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
haloperidol-5273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63291
endosome	GO Cellular Component Annotations 2015	1.0	null
MCF7_PF-573228_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180189
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933827
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62753
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940018
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45487
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05070188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34011
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13708
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45193
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09024
CORVET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48701
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.13754
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02721
m2 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44712
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-361-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-4329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8252
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02734
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
VP229	DepMap CRISPR Gene Dependency	1.0	3.52714
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K00566460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36061
MCF7_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217686
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228497
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058178
BRD-K06816455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41217
hsa-miR-320c	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
MCF7_Mesna_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0100733
RHJT	DepMap CRISPR Gene Dependency	1.0	2.35453
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	3.77309
fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401765
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14217
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_148_KD_Zfp407_SRP051775	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:I04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01515
BRD-K46412655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38556
PMC10349775-432_2022_4445_MOESM1_ESM.pdf-24-NFATC4_NFATC4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2847_Mut_AKT_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.87672
Microglial cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11935
Oligodendroglioma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K39223744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24742
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20103
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48549243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08851
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
small gtpase mediated signal transduction	GO Biological Process Annotations 2015	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48372955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7979
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44669
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04032
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-1026-SM-3MJGF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862155
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02557
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105675
GSE168797_4_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.078016
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
PMC9288051-13046_2022_2428_MOESM5_ESM.xlsx-Super_enhancers_in_T-ALL3-CLOSEST_GENE_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933631
biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060049
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883954
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.666809
BRD-K41306114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1984
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Dacinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00773062
esophagitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.604591
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Amyloplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
Lysosomal proton-transporting V-type ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.628
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.096414
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74641261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32628
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5794
GSE244940_0_v_1_edf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82605
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1084
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.04684
AKT1	Pathway Commons Protein-Protein Interactions	1.0	null
APP	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14685_KO_Lkb1_ERP006813	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.241
choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.687491
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02976
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
BRD-K58044926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27816
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26279
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03321
Necrosis	CTD Gene-Disease Associations	1.0	2.32136
Sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
GSE168797_4_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.23375
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88621
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077541
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.871483
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALM1	Hub Proteins Protein-Protein Interactions	1.0	null
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633953
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.94334
GSE111245_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-760	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GTF3C2	ENCODE Transcription Factor Targets	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07056
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30201
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854056
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
valproic acid_mus musculus_gpl1261_gds3002	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TGW	DepMap CRISPR Gene Dependency	1.0	2.00887
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35071
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85718
Esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87463
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5591-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.39604
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16545
Synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.62268
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68275
MNAT1_Deficiency - Ablation_GDS2561_690_mouse_Heart - 4 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11158
PPAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72225
Multimerin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
MCF7_Streptozotocin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0299325
N6-methyladenosine-6732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.90769
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78877
many	GeneRIF Biological Term Annotations	1.0	null
Sjogren'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922565
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19551
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7263-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:C11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89255
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sublingual gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
PMC10534007-Table_2.xlsx-S3_unique_up_MSC_V-817_elements_included_exclusively_in_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acquired Immunodeficiency Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chromaffin granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.224913
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.45621
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896928
sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173611
GSE171837_3_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546533
BRD-K57616143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6217
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38166
BRD-K84761515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12124
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0028
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35851
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15947
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ar4-2j cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09208
harman-4584	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K25363217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00165
MCF7_RG108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148105
mantle zone of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54072
TO175T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53738
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04671
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
loxapine-6694	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75814223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2749
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	2.19649
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
8305C	DepMap CRISPR Gene Dependency	1.0	2.34832
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.57571
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04599
CORL279	CCLE Cell Line Gene CNV Profiles	1.0	1.48899
RBBP5	ENCODE Transcription Factor Targets	1.0	null
nifedipine-6006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
myosin binding	GO Molecular Function Annotations 2015	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
valproic acid_mus musculus_gpl6885_gse41020	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-30c	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.934613
protein secretion	GO Biological Process Annotations 2023	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83832060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26657
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
PL-21	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.15135
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38356
rofecoxib-256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE212299_3_v_0_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
secretory granule membrane	GO Cellular Component Annotations 2025	1.0	null
anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258243
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44868
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40308
MCF7_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154243
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15758
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13392
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
secretory granule	GO Cellular Component Annotations 2015	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19991
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131287
cefoxitin-3477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE226452_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879428
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.825877
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42359
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H322 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
hsa-miR-1286	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.27193
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein localization to plasma membrane	GO Biological Process Annotations 2023	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ranitidine-5425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.485
BRD-K92826631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79308
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07785
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48235506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34858
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963667
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14597
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.12668
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30854
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7493
BRD-K47417426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18557
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.12751
MCF7_SGI-1776 free base_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174934
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49862
BRD-K60517939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06225
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP3_cds_exp_up-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77984
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_downregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
MOLM13	CCLE Cell Line Gene Expression Profiles	1.0	1.5338
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.188
nizatidine-3047	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.36763
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30335
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043679
BRD-A56427952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08363
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE85302_4_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
MCF7_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172282
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3015
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.617796
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45892
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96347
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829843
PMC6944231__F3	PFOCR Pathway Figure Associations 2023	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980525
Anterior amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05427
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA1_448_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74128
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91447
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42653
BRD-K95551067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09023
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW156	DepMap CRISPR Gene Dependency	1.0	2.64825
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	3.51896
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.22664
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04535
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
removal	GeneRIF Biological Term Annotations	1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Griscelli syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
mantle zone of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13452
BRD-K46085646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03204
BRD-K76087207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17848
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1618
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13707
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02343
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lynestrenol-6756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE198036,GSE198041_0_v_2_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEL9217	DepMap CRISPR Gene Dependency	1.0	7.32673
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2507
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3536
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC2218	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.64858
Duodenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65322
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0248
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K92433833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19898
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26025
dequalinium chloride-5396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55059
hexamethonium bromide-6620	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
hsa-miR-4732-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
CRCGN015_MCF10A.TP53.M_24H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2442
mantle zone of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11098
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6782
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.3809
BRD-K20879770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19315
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01666
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98938484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16832
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04664
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
PLPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21582
BRD-K12492021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34777
BRD-K68705041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24521
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
GSE115763_3_v_1_klf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02483
SK-MES-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	4.07411
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.556865
BRD-K82922770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11824
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
novobiocin-4392	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899824
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828869
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72889
BRD-K61711624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2168
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56694
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975418
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Presynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.666
bhlha15_17170023_pancreas_lof_mouse_gpl339_gds1731	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.198137
tretinoin-447	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18015
MCF7_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124319
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28685
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73051782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12604
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854035
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	1.4321
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	-1.0	null
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916126
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.859
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19071
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0621
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subapical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
hsa-miR-27a	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51422
Supramolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35374
BRD-K69903198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9771
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.63238
MCF7_Alendronate sodium trihydrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128631
foreign-body giant cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19116
bacitracin-3109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14969_KD_Phf23_SRP248452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.84569
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31425
Mast cell granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.065
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66187822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01142
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9235
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_14348_KD_CDK12_SRP223931	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K54456668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0853
BRD-K45635721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4966
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893563
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35669
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14253
Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Martsolf syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
hsa-miR-3677-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPI-coated Golgi to ER transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.992
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
a72	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
BRD-K56354139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86226
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25418
GSE202434,GSE202438_6_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04531
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34168
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.860458
Post-translational protein modification	Reactome Pathways 2024	1.0	null
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32475
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00542
MCF7_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181289
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96482
GSE247862,GSE247863_0_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.767
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.51049
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.745451
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Brain microvessel endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
MCF7_Epothilone A_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131366
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28325
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391176
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
UT7	CCLE Cell Line Gene CNV Profiles	1.0	2.61768
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988742
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-2964a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K72694472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02447
BRD-A51381734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20052
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Apical recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
BRD-K90155857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33906
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848841
pioglitazone-7506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22746
GSE178255_3_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87689
PMC12410147-NIHMS2099518-supplement-5.xlsx-z-scores_E4DEG_DGATiLPS_vs_LPS-Z-scores_for_genes_differentially_expressed_when_comparing_DGATi_LPS_treatment_to_LPS_alone_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44834268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71986
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11732
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2671
pancreatic acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36541
cyclothiazide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36785
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.47729
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12735
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73717
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05397
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48999
HDAC6	ENCODE Transcription Factor Targets	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMRC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77742
ZNF384	ENCODE Transcription Factor Targets	1.0	null
secretion	GO Biological Process Annotations 2015	1.0	null
edrophonium chloride-1519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20478
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16656
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.26534
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
secretory granule membrane	GO Cellular Component Annotations 2023	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12827
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COGN305	DepMap CRISPR Gene Dependency	1.0	2.48023
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74608
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20556
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05457
Lung adenocarcinoma_LUAD_TCGA-05-4396-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81926
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50133
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13284
Lung squamous cell carcinoma_LUSC_TCGA-21-5787-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11042
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94115999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64157
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q8-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52124788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05883
pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.109626
exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19356
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882848
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29184
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2132
BRD-K46107062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37649
CRCGN015_MCF10A.WT.HP_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18362
BRD-K95615652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15228
MET_knockout_258_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.894025
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K13543055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05716
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WM793B	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.06604
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76597
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
granules	GeneRIF Biological Term Annotations	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.918206
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12732
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.33451
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
secretory	GeneRIF Biological Term Annotations	1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133669
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67A-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleoside-triphosphatase activity	GO Molecular Function Annotations 2015	1.0	null
GSE201309_5_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.6791
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62184784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23323
Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09441
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17088
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_PJ34_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167477
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940764
Prestwick-685-4705	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95006
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.09011
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.652159
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09585
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
icSARS CoV_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04781
Root pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
hsa-miR-4319	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
THP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.31668
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31311
peptidyl-amino acid modification	GO Biological Process Annotations 2015	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985736
NB13	DepMap CRISPR Gene Dependency	1.0	2.10813
GSE57871_1_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17058
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12792
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05321
PMC7529806-41467_2020_18638_MOESM7_ESM.xlsx-Supplementary_Data_4-Supplementary_Data_4_TG_of_EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05015930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39487
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02811
GSE202434,GSE202438_8_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39671
MCF7_Ki16425_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155283
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52226
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.919982
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80210288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16691
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69992
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18081427-TableS8	GeneSigDB Published Gene Signatures	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980399
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
p1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-2.32732
CRCGN011_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.074
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14014
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062493
BRD-K99736408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15607
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314409
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271256
GPALPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28686
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04055
BRD-K78741913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68932
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0263567
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.47012
positive regulation of regulated secretory pathway	GO Biological Process Annotations 2015	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39429
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53023
Lung adenocarcinoma_LUAD_TCGA-86-8359-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
cortex	GeneRIF Biological Term Annotations	1.0	null
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15389388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2062
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845333
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875729
BRD-K19020285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16293
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09784
Sarcoma_SARC_TCGA-FX-A3NJ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11098
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15684
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.19668
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89345
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
octopamine-3112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08803
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00252
presence	GeneRIF Biological Term Annotations	1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.288915
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_S-Ruxolitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127115
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21879
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50385
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94785
prednisone-1478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K80424876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2526
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86832
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071364
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92415
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Porosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
COPII-coated ER to Golgi transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.839
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HZ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mutant	GeneRIF Biological Term Annotations	1.0	null
BRD-K30674856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13427
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46003
MCF7_Vandetanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162531
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26444
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932417
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1027_KO_Ovgp1_SRP379795	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.2316
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048875
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03565
BRD-K30761927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06486
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247399
BRD-K58888361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01197
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.8089
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90741
GSE202434,GSE202438_7_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K98018160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65742
amantadine-3280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.44111
BRD-K19381111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41338
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.386679
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126165
REST	ChEA Transcription Factor Targets	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTNNB1	ChEA Transcription Factor Targets	1.0	null
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11599
BRD-K88662980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78818
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36668
MCF7_Roscovitine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203797
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845429
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09568
hsa-miR-4505	TargetScan Predicted Conserved microRNA Targets	1.0	0.026857
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15766
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54937
domperidone-5701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0241336
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831241
BRD-K35617935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69277
Lung squamous cell carcinoma_LUSC_TCGA-43-2581-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0239163
MCF7_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0209387
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58155058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14957
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08564
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.246442
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01428
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03536
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10665
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39267
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53527
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-BatSRBD_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.66527
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33365
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0549
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22508
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883139
PMC7532093__F8	PFOCR Pathway Figure Associations 2023	1.0	null
MCF7_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119916
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13646
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MCF7_RG108_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152007
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81429
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.953
pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.549709
AG-013608-5904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9715
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15072
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02192
SARS-dORF6_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.3904
basointermediate isthmic reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49506
agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.507657
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980399
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243294
BRD-K06886551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59428
weibel-palade body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.560528
BRD-K28846321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16368
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0537
TAF1	ENCODE Transcription Factor Targets	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.455
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3455
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23945
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55883
Sarcoma_SARC_TCGA-IE-A3OV-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.817
BRD-K49461735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75629
hsa-miR-4284	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Hypertrophy	CTD Gene-Disease Associations	1.0	1.86756
A549_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014611
BRD-K04275703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06382
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.66059
BRD-K88150784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0135
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58118
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94637240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05598
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36811
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02908
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4904
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
att-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.716651
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3339
intermediate part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13452
BRD-K53186055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10515
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5404927-elife-24463-supp1.xlsx-1b_ERM_proteome-Gene_names_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76174882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6713
Lytic vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60557
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
ERBB2_knockdown_234_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.48851
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CH-27 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
epiandrosterone-5687	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166138
CP-690334-01-3826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13208
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100547_HIP_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05187
A-Vietnam-1203-2004(H5N1)_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.82067
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of transport	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05149
Adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.561
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8261
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.71455
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hydrolase activity, acting on acid anhydrides	GO Molecular Function Annotations 2015	1.0	null
clofilium tosylate-4492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MOLM-16	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8105
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.8512
solasodine-3749	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28205
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90793170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06947
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.828171
tiapride-4686	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
BRD-K49945344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78312
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.95409
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26762
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.829
Dermatitis, Irritant	CTD Gene-Disease Associations	1.0	1.06333
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.853329
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866126
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18222
IGROV1	DepMap CRISPR Gene Dependency	1.0	7.22397
BRD-K10027041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33479
Thiopurine S-methyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60378
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90927
dextromethorphan-5401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	1.88575
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39504
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
Lung Diseases	CTD Gene-Disease Associations	1.0	1.02373
GTEX-SIU7-0926-SM-4BRX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08937
Neutrophil degranulation	Reactome Pathways 2024	1.0	null
graves' disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.268332
MCF7_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128788
CHD1	ENCODE Transcription Factor Targets	1.0	null
Bone sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
BRD-K56373119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27706
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
GSE241108_1_v_0_sulfasalazine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06078
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49208610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21956
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Clevudine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196987
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24814
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.29178
PMC11058205-42003_2024_6202_MOESM6_ESM.xlsx-Data3a_DirectGene_CEBPA-Data3a_Genes_directly_regulated_by_CEBPA_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14235
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37695
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23815
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45874102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60042
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.914157
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880359
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
rab26	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77586
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of synaptic vesicle localization	GO Biological Process Annotations 2015	1.0	null
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1805
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lidocaine-4596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86373784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55901
GSE246335_4_v_5_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8872993-41380_2021_1274_MOESM5_ESM.xlsx-Table_S7-Supplementary_Table_S7_TCF7L2_Target_Genes_Identified_by_Integration_of_RNA-seq_and_ChIP-seq_Data_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196699_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
transport vesicle	GO Cellular Component Annotations 2015	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
BRD-K81568980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37383
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1845
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
p3 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43262
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.846
biological regulation	GO Biological Process Annotations 2015	1.0	null
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.18991
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36397
newborn respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178682
hsa-miR-1280	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
naloxone-5606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328628
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897112
Lung adenocarcinoma_LUAD_TCGA-44-6776-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15082_KD_Ehmt1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7233
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fluocinonide-3839	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
esophageal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.243645
GSE94849_7_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	1.0	3.40838
Hypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
aminohippuric acid-5394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40614
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0247
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.117
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mitochondrion	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26069
metronidazole-1503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
MCF7_Aminoglutethimide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182548
thioridazine-5916	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06383
STAT1	MotifMap Predicted Transcription Factor Targets	1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
ion binding	GO Molecular Function Annotations 2015	1.0	null
EVSAT	CCLE Cell Line Gene Expression Profiles	1.0	2.39013
BRD-K25993054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58636
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894448
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17199
aconitine-2776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
esophageal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.531154
GSE186287_1_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Multivesicular body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.91
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44394
MOLM16	CCLE Cell Line Gene Expression Profiles	1.0	1.43538
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09599
regulation of regulated secretory pathway	GO Biological Process Annotations 2015	1.0	null
Agnosia	DisGeNET Gene-Disease Associations	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76445
BRD-K41135617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07551
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14902
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78315404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45883
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
BRD-K27320944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53179
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Small GTPase superfamily, Rab type	InterPro Predicted Protein Domain Annotations	1.0	null
TBX2-35687133-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898765
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1594
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hepatic vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.759416
myb_16205643_mcf7_gof_human_gpl96_gse2815	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.07879
Fibrosis	CTD Gene-Disease Associations	1.0	1.8965
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06675
Perturb_10353_KO_Hbb_SRP333852	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82449
ATM_KD_GSE54268_662_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Secondary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-3129-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SUM-52PE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
promazine-3927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.340388
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2088
BRD-K07230804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13699
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861342
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60945
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63031
PMC7532093__F8	PFOCR Pathway Figure Associations 2024	1.0	null
SR	GDSC Cell Line Gene Expression Profiles	1.0	1.82509
mebhydrolin-3269	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
meticrane-5984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14952_OE_Tnfsf14_SRP148550	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
other organism	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.376586
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.2025
BRD-K76885311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10554
propidium iodide-2541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.78239
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1219
AU565	CCLE Cell Line Gene Expression Profiles	1.0	1.52406
3-hydroxy-DL-kynurenine-5276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
crypt	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.452198
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.273926
IFITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18927
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
megestrol-5013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141391
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2581_KD_AHR_SRP032510	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.74887
pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58322
Lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87531
BRD-K35133923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73258
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dacryoadenitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.148
RUNX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50811
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Patupilone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130366
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
methoxsalen-6661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
16322246-Table1	GeneSigDB Published Gene Signatures	1.0	null
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	1.0	1.64682
Osteopetrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124471,GSE124488_1_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.54938
Dorsal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.13754
RPH3AL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35132745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05113
BRD-K48777375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13893
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996837
Transplanted Heart Complication_Myocardial tissue_GSE582	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.96112
transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.510418
GSE108675_2_v_1_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391176
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.140386
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5656
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K31437957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48252
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334865
BRD-K84745303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26847
paroxetine-3904	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-5096	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.45296
Nephritis	CTD Gene-Disease Associations	1.0	1.30881
NR2F2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1207-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
BRD-K12517207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34188
thiamazole-3432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trifluoperazine-5442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dimethadione-3029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nordihydroguaiaretic acid-6182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941536
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HNF4G	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36685
vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.14433
BRD-K08607520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01226
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27257
SKNFI	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20902
BRD-K39965317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79845
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RPMI8226_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.08041
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47402
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52872067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71615
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF32	Pathway Commons Protein-Protein Interactions	1.0	null
icSARS CoV_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.52691
PMC7780220-12943_2020_1301_MOESM8_ESM.xlsx-Fig_3A_RNA-seq_DEGs-Summary_701_LPS-induced_DEGs_361_THZ1-sensitive_DEGs_in_blue_of_macrophages_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4387_KO_STAG2_SRP348449	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.8931
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2043
BRD-K57687960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94198
UBTF	ENCODE Transcription Factor Targets	1.0	null
BRD-K36725646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59187
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96385
polymorph layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13452
MCF7_ENMD-2076_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111433
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.058817
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8791942-41398_2021_1766_MOESM7_ESM.xlsx-LPS_DEGs_Heatmap-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-8067-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.38405
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEP55	Pathway Commons Protein-Protein Interactions	1.0	null
17699763-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39376
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE222598_1_v_0_sf3b4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.68889
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1308
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
mesomere 2 (preisthmus or caudal midbrain)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05028
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08032
Hermansky-Pudlak syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cefotetan-4116	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5048
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938384
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1915	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.37741
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0387
regulation of secretion by cell	GO Biological Process Annotations 2023	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48586
first (dorsal) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15242
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5386
MYOD1	ENCODE Transcription Factor Targets	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.625061
azurophil granule membrane	GO Cellular Component Annotations 2025	1.0	null
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54712
cellular_component	GO Cellular Component Annotations 2015	1.0	null
H3K79me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.972117
449 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840346
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15658
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11475
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987873
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_24_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
highly	GeneRIF Biological Term Annotations	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36825
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
procyclidine-3330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58205
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35251
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855213
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994102
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19249
luminal	GeneRIF Biological Term Annotations	1.0	null
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.73
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2171
triamcinolone-2241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.98766
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08991
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	0.823981
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843773
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89498
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
ERBB2_druginhibition_7_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.53505
Psychomotor Disorders	CTD Gene-Disease Associations	1.0	1.10769
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15227
hsa-miR-141	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833539
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.787299
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05221385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21875
Perturb_2014_KO_Xbp1_SRP061216	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Nerve sheath cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
MOLM-13	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.80934
BRD-K70276322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14252
GSE115363_2_v_4_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Basal part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
basophilic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296372
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60754
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE211286_1_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00970182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03233
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14781
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836648
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26785
BRD-K88802328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42424
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3192	TargetScan Predicted Conserved microRNA Targets	1.0	0.013856
intermediate stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98273
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
A-2058 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
OE19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K73769678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.85588
hsa-miR-142-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.583431
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889229
Granulocyte-monocyte progenitor_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260606
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42294
raloxifene-3480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21162
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IM9	DepMap CRISPR Gene Dependency	1.0	3.216
BRD-K93698227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04089
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90781
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.41494
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973948
PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isocarboxazid-4706	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE156033_1_v_2_sparc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OSC20	DepMap CRISPR Gene Dependency	1.0	2.87187
PF-01378883-00-6368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PF-00562151-00-5917	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00427
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02465
Lung Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37256
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28365
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.67675
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27186
BRD-K02024244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47677
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.19312
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN008_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05565
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_7_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02805
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2195
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.933263
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67155
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.20658
BRD-K55562948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30456
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160611
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25398
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC1	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.04538
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIV_Infected-mDC_None_GSE42058	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79433
Azurophil granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
A549_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143515
diphenhydramine-6020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_169_KO_Cebpd_SRP316336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215534
components	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-375	MiRTarBase microRNA Targets	1.0	null
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286026
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13792178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13281
hsa-miR-4763-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866437
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
LK2	DepMap CRISPR Gene Dependency	1.0	2.08461
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Acute Lung Injury_Lung Tissue_GSE1871	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.969803
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45142
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01839
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888436
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2808
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.94729
parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.933195
etifenin-4117	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10468
Ovary	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE179002_4_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.910946
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49126
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0644
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.90263
BRD-K75845970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0559
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00043
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9968
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2822
KLF4	ChEA Transcription Factor Targets	1.0	null
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.277
etamivan-2879	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K46609723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30013
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325552
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73227539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0344
transport	GO Biological Process Annotations 2015	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25686
proglumide-3972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.701
HCC1143_BREAST	CCLE Cell Line Proteomics	1.0	3.16166
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredPeptides-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5059
CREB1_01_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59682
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22034
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36149853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00745
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Perturb_4204_KO_Top1_SRP072888	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.69404
BRD-K31748787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13121
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
RPMI8402	CCLE Cell Line Gene Expression Profiles	1.0	1.64857
MCF7_Clevudine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020955
Sepsis_Splenocyte_GSE4479	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.44817
pheochromocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196232
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
zymogen granule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863156
estradiol_homo sapiens_gpl570_gds3217	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16233
piribedil-2951	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.381481
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919088
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.079
exocytosis	GO Biological Process Annotations 2015	1.0	null
secretogranin	GeneRIF Biological Term Annotations	1.0	null
r3 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06708
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98273
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7XC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.21465
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.725
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.696404
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43755
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Navitoclax_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199735
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lytic vacuole membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98906
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3445_OE_Sca17_SRP248035	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.37982
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.57369
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1765_KO_Myh9_SRP363034	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
alclometasone-6094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829945
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Pedunculopontine nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92769
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PX-01A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic secretion	KEGG Pathways 2026	1.0	null
GSE154081_1_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Anorexia	CTD Gene-Disease Associations	1.0	1.12323
peduncular subparaventricular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14781
hsa-miR-670	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_3_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769027
Type 2 diabetes mellitus_Endocrine Pancreas - Islet Cell of Langerhans - Beta Cell (MMHCC)_GSE6428	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.36342
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14237
CD1C-CD141- dendritic cell_Blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17816
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10613
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5038
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24112
pregnenolone-2856	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43254
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6143
prochlorperazine-5010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE162384_1_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05222558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03324
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41979
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.14674
Lung adenocarcinoma_LUAD_TCGA-97-7937-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.0461
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14868
placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.384822
Oligospermia	CTD Gene-Disease Associations	1.0	1.2137
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
BRD-K52436508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14265
neuronal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102779
Perturb_13374_KD_L54E2_SRP225936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.15256
BRD-K27121064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35977
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43262
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flotillin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
Perturb_170_KO_Cebpd_SRP316336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01176
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56544
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36426
PMC3899188__F1	PFOCR Pathway Figure Associations 2024	1.0	null
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60475
MCF7_Prednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020756
BRD-A39506880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23674
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10148
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52769
hsa-miR-3654	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hsa-miR-4727-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
Perturb_1428_KO_Adm2_SRP399375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.79633
organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09108
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938998
lomefloxacin-2310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
demeclocycline-3404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K39087188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47505
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.63084
kidney	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_KW-2449_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218021
18234966-Table2	GeneSigDB Published Gene Signatures	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.09731
hsa-miR-4319	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17542
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21832
hsa-miR-4292	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33294
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EK-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58828
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
chr19_11331396_T_TC_b38	GTEx eQTL 2025	1.0	1.1196
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06773
GSE104604_1_v_0_eif5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80381
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61118
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune System	Reactome Pathways 2024	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K40300525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0552
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03398
PMC12234789-41467_2025_61560_MOESM3_ESM.xlsx-Supplementary_data_1-Only_YY1_IP-MS_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32853
MCF7_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138097
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060255
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26988
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.273
BRD-K30053194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26765
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K36me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12174
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT1:STAT1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44814060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19362
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2171
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1736
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07773
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965497
Lacrimal gland acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.595
CRCGN011_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2004
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.04904
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880654
hematopoietic cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84042
15474998-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22495
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14322
Perturb_13684_OE_JMJD3_SRP151752	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7421
Early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.756
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0591
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34043
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44796
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
MCF7_Costunolide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177613
Mucous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
Learning Disorders	CTD Gene-Disease Associations	1.0	1.67912
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15819
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220604
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147876,GSE147877_4_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193249_0_v_1_gpx8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.4565
PMC6605752-JEM_20181726_TableS1.xlsx-MYC_translational_targets-Unnamed_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPH3A	Pathway Commons Protein-Protein Interactions	1.0	null
rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28367
cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.184424
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14688
betulinic acid-3281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
decreases	GeneRIF Biological Term Annotations	1.0	null
lysosomal membrane	GO Cellular Component Annotations 2023	1.0	null
Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.984
gramine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25868
GSE132408_0_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.20574
Endolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34738
cytoplasmic membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
MCF7_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220097
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
vesicle docking involved in exocytosis	GO Biological Process Annotations 2015	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910644
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19493
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905939
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980763
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930172
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.94544
BRD-K10182289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29107
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083701
BRD-K54785691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66261
macromolecule methylation	GO Biological Process Annotations 2015	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.30978
trichostatin A-6171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
catalytic complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042109
PMC10181932-41588_2023_1366_MOESM4_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_Additional_information_for_all_SOX9-dependent_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
cellular localization	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5432-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73693
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tonzonium bromide-3080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF3C2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Sirtinol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186026
luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
BRD-K48412518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78315
tiabendazole-2840	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
secretory granule	LOCATE Curated Protein Localization Annotations	1.0	null
HMMR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36302
NCIH1836	DepMap CRISPR Gene Dependency	1.0	3.08731
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24635
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175953
Seizures	CTD Gene-Disease Associations	1.0	1.03308
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870488
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00112
peri-centrosomal recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
p2 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15696
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.271886
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02244
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2114
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_5_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0254107
Perturb_14529_KO_Gata4/Nr5a2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.4342
amiprilose-4119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isotretinoin-6017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.946087
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920743
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23852
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0017
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93552
BRD-K43108627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29754
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
guaifenesin-4371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29661
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868938
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.885993
hsa-miR-199a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
DROSHA_02_01	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60241
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0926-SM-2I5GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870639
Lung adenocarcinoma_LUAD_TCGA-05-4405-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Terminal bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59076
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870751
icSARS CoV_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61563
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482428
resting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.273346
Breast disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6470_KD_PDRG1_SRP314383	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867337
MCF7_Alisertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126697
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18612
SK-N-BE(2) cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
Fluticasone	DeepCoverMOA Drug Mechanisms of Action	1.0	0.24
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19073
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05012
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.03993
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19252
pheneticillin-6105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JHU022	DepMap CRISPR Gene Dependency	1.0	2.28114
NCIH1573	DepMap CRISPR Gene Dependency	1.0	4.35559
Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90843
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6021-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.22855
KPL1	CCLE Cell Line Gene Expression Profiles	1.0	1.7513
BRD-K58268854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16401
carbenoxolone-3353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K95900761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08079
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19503
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
labial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32753
gtp binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04523
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11653
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9461
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13279882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01593
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18096
BRD-K45620289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.988
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060717
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pirinixic acid-368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041771
membrane docking	GO Biological Process Annotations 2015	1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.624658
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62388
BRD-K30025024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09068
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
c32	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4429	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
BRD-K98805845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11996
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
dorsal part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08458
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K79937734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97524
BRD-K24206299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02036
BRD-K08233096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60287
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58796
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66984
BRD-K13534347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69503
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr19_11324494_CCAGCTAAA_C_b38	GTEx eQTL 2025	1.0	1.17266
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29669
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMRC20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41308
procainamide-5663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135030_8_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43651
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08365
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60558
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01276
PRRX2	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43007
BRD-K06842972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85767
HMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.957972
MCF7_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220755
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80583
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1235
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86819
trans-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.975
wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387027
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.405
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.26166
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054685
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22453
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.65312
Anammoxosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34519313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27879
MCF7_Toremifene Citrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116555
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66433
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01498
BRD-K49923205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59163
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052435
BRD-K72156149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61056
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sodium phenylbutyrate-502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_WHI-P154_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130708
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_02_39	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62054
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
azlocillin-6262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908764
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.77036
naltrexone-2209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.12594
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19291
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01910220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40601
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7253
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2092
NAMPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37455
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03103
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15192
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dantrolene-2329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2867
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease of exocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
CRCGN015_MCF10A.TP53.M_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08865
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54387
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921486
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14573
Genital Diseases, Male	CTD Gene-Disease Associations	1.0	1.02596
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.13754
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.45032
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44716
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pirenzepine-7226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124211
BRD-A22773530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02226
regulation of secretion	GO Biological Process Annotations 2015	1.0	null
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SCC25	DepMap CRISPR Gene Dependency	1.0	2.237
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
formation	GeneRIF Biological Term Annotations	1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
practolol-5664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177996
MCF7_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0252452
ifosfamide-3485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49635910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79685
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.59625
CTV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.77941
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932367
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.548914
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SYM-2206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97859
PMC10154691-Table2.xlsx-Table_2B-Table_2B_Significantly_differentially_expressed_AR_target_genes_fold_change_Log2_1_and_FDR-corrected_p-value_0_05_AR	Rummagene Transcription Factor Associations 2026	1.0	null
nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.09303
IA-LM	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79238
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.07608
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-P6-A5OF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Virion transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45485
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66818
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05019
guanadrel-3438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.39662
BRD-K32893898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02839
496100303_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10914
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glimepiride-4973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Ramelteon_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162122
Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHOst cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Hypercholesteremia_Hepatic Tissue_GSE3889	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.24154
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
clioquinol-5623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22258
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MV411	CCLE Cell Line Gene Expression Profiles	1.0	1.73763
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53078
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.874591
B-CPAP	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.30553
diethylstilbestrol-3429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	2.04163
NB10	DepMap CRISPR Gene Dependency	1.0	4.97865
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1118
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.06844
Well Differentiated Oligodendroglioma	DisGeNET Gene-Disease Associations	1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.71212
Prestwick-1080-4354	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6516-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9534852-41598_2022_20572_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_S4_Transcriptomic_data_related_to_AHR_function_considered_for_metabolic_reconstruction_model_generation_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86912219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01508
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0198
BRD-K09376533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07225
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
exocytosis	GeneRIF Biological Term Annotations	1.0	null
Perturb_17418_KO_Myd88_ERP115704	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.78037
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28595
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897972
BRD-K20028734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56307
hsa-miR-4786-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9753
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76486
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95985
Zymogen granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.287
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.57935
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70608
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.848382
MSX1_01_281	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59271
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17746
BRD-K08009212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36745
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22053
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926997
PMC6288913__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE179693,GSE179694_4_v_2_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17483317-TableS5	GeneSigDB Published Gene Signatures	1.0	null
HTC-C3	GDSC Cell Line Gene Expression Profiles	1.0	1.58446
guanyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
ondansetron-6153	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0156
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.46986
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.95412
BRD-K52685199	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95523
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.8271
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE184884_6_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
desipramine-3212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K43610632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52414
eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03794
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.30083
BRD-K54224946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21714
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331927
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854971
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58392
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.05042
SW1417_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.10131
MCF7	CCLE Cell Line Gene Expression Profiles	1.0	1.61026
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ITK_knockout_241_GSE12465	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.41758
PMC11244912-media-3.xlsx-Sheet2-ESR1_mutation_E2_Co-Down_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
ras protein signal transduction	GO Biological Process Annotations 2015	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22008
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1153
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895814
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965533
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3557
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma, Non-Small-Cell Lung	HuGE Navigator Gene-Phenotype Associations	1.0	null
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO Molecular Function Annotations 2015	1.0	null
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71905
Perturb_9484_KO_Tcf7/Lef1_SRP251706	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.34041
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857598
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41057
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54072
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26148
CRCGN009_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02295
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gramine-2143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.793313
NACC1	ChEA Transcription Factor Targets	1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of regulated secretory pathway	GO Biological Process Annotations 2023	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_2_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45964657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35063
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60833
Brush cell (Tuft cell)_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Pons, behavioral state related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51303
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5438
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.80833
azlocillin-2727	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.179459
TKKK	DepMap CRISPR Gene Dependency	1.0	7.02889
USF1	ENCODE Transcription Factor Targets	1.0	null
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09193
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7773-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein methylation	GO Biological Process Annotations 2015	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51335
ruminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16426
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26006
STAT3_OE_GDS3444_576_mouse_Cultured embryonic stem (ES) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.86497
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02613
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.779
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229299
Vegetative stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.26327
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43493
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26896
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37948
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Clathrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29101
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83013052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29286
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19411393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72907
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAB geranylgeranylation	Reactome Pathways 2024	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1865
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03934
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
hsa-miR-4324	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Alcohol Use Disorder	DisGeNET Gene-Disease Associations	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47536398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19022
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29594
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061093
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30904
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40389
BRD-K99609051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15664
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Osteosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1543
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11037
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01764
CRCGN015_MCF10A.TP53.M_24H:B24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02435
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-0326-SM-48FDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920446
neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.339261
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alpha-estradiol-6169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41024
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31704
OCIMY5	DepMap CRISPR Gene Dependency	1.0	3.17535
Sorting endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28599
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39787
diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.589001
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
naphazoline-1466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21967
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48387
Corneal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.05085
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21642
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-320a	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.22072
BRD-K23763017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62504
corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280364
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22802
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073422
PMC7884075__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
rosiglitazone_homo sapiens_gpl96_gds2705	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lithocholic Acid	CTD Gene-Chemical Interactions	1.0	null
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.608475
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26536
CRCGN015_MCF10A.WT.HP_24H:K15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09281
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11632
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Lomustine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230851
CRCGN015_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33574
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43579
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04417
endomembrane system	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.674196
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0015
Eye Abnormalities	CTD Gene-Disease Associations	1.0	1.01814
Perturb_788_KD_Foxk2_SRP145105	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sporophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
STAT3	ENCODE Transcription Factor Targets	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.956
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33394
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.827
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07517
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82216975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71347
signal transduction	GO Biological Process Annotations 2015	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.30848
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
PMC9288051-13046_2022_2428_MOESM4_ESM.xlsx-Super_enhancers_in_AML3-CLOSEST_GENE_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78917
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2301
Perturb_3773_KD_CCNK_SRP041162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3678
Acute Myeloid Leukemia_LAML_TCGA-AB-2825-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16834
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
eboxes	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K57575504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84555
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14932
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.77853
mist1	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03116744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19529
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06279
BT474	CCLE Cell Line Gene Expression Profiles	1.0	2.37342
BMMC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
factinrich	GeneRIF Biological Term Annotations	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980399
zymogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.35375
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5441_KO_Zeb2_SRP261907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7938
RNASET2-deficient cystic leukoencephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843515
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00478
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37833
BRD-K01278504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21856
GSE115328_6_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15242
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866806
MCF7_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120681
directly	GeneRIF Biological Term Annotations	1.0	null
Immunological synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
GSE82104,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
BRD-K77832645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1518
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RI1	DepMap CRISPR Gene Dependency	1.0	2.99966
Golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075386
Polymeric cytoskeletal fiber	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
MCF7_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128078
PMC12410147-NIHMS2099518-supplement-3.xlsx-z-scores_DEGs_DGATi_LPS_vs_LPS-Z-scores_for_genes_differentially_expressed_when_comparing_DGATi_LPS_treatment_to_LPS_alone_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126463_4_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
16288205-GeneTable2	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17286
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55606
GSE240386,GSE242143_1_v_3_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65598536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53099
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970217
Perturb_6175_OE_Zeb1_SRP187711	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.737
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17114
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71916
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0123
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.21373
Prestwick-920-3118	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K27026825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53638
testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.179239
CRCGN008_HEPG2_24H:J06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.319
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58902
Hepatic Cirrhosis_Hepatic Tissue_GSE1843	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.33083
BRD-K96945047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35751
Golgi cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26563
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2559
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47107
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955871
flurbiprofen-5634	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.960479
vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995884
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02087
Lung adenocarcinoma_LUAD_TCGA-78-7152-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933998
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49673
CBX3	ENCODE Transcription Factor Targets	1.0	null
Subglottis benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92180676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72719
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07645
BRD-K51919278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58139
Osteoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Presynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_146_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139801
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.084
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60874
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2857
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28133
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08051
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30718
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.90369
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_5_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116299_0_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LU-99A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.807907
BRD-K15160749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13378
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.562
finasteride-6062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3678
BRD-K40610042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03855
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.895436
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25777
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67778
Bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
GSE185519_1_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78L-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-XBED-1226-SM-4AT5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86255
CP-863187-7508	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0227442
BRD-K01077691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33564
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49741
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27455
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83376
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43392
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938086
membrane organization	GO Biological Process Annotations 2015	1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CGTHW1	CCLE Cell Line Gene CNV Profiles	1.0	2.03046
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854366
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
synaptic vesicle transport	GO Biological Process Annotations 2015	1.0	null
Sjogren's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
Granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.707
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061505
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
blocks	GeneRIF Biological Term Annotations	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00316
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59856
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1086
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059728
AR4-2J cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.703
BRD-K40061857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0928
gtpase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K09863466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59487
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0319
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0304
BRD-K90047132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34489
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1632
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S13-Table_S13_MR_resluts_of_brain_pQTL_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.94841
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05934
nalidixic acid-2297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15819
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.35989
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07814
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.32667
guanyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K71427375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04436
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67128
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
BRD-K58137366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31479
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6111
hsa-miR-4690-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92462786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27791
Perturb_5703_OE_H2Aa/H2Ab1_ERP108769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.6323
Hyperplasia	CTD Gene-Disease Associations	1.0	1.93751
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983925
PC-3_[JPC-3]	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.22141
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.922667
20559987-TableS3	GeneSigDB Published Gene Signatures	1.0	null
MCF7_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0284737
Perturb_4721_KO_Setd5_SRP117752	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.51768
positive regulation of regulated secretory pathway	GO Biological Process Annotations 2025	1.0	null
MCF7_PF-3845_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134487
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980399
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.34417
MOLT-4	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.0146
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.10688
BRD-K32370845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41058
MCF7_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167437
Acute Myeloid Leukemia_LAML_TCGA-AB-2834-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bepridil-1274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
bemegride-3389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05103
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27061
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12341
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MCF7_RG108_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144202
HSMM	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.20425
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
ERBB2_knockdown_233_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.59176
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19404
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849739
BRD-K93268593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08466
GTPase activity	GO Molecular Function Annotations 2025	1.0	null
ascorbic acid-3225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874372
hsa-miR-670	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39777
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.42831
placental insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.370737
dipyridamole_mus musculus_gpl6246_gse43833	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
F36P	CCLE Cell Line Gene CNV Profiles	1.0	2.33391
Lung squamous cell carcinoma_LUSC_TCGA-22-0944-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875729
MCF7_AT9283_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116939
BRD-K17514980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40098
GTEX-V955-1326-SM-4JBHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905035
MYB-21317192-ERMYB-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K79635719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54806
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Celecoxib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221276
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20655
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41310621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7315
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6637
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35704
estradiol-365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956021
Golgi apparatus subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.987
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43924
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57595
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46165
tolmetin-3347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867927
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25207
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39033
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86142
Early cardiac repolarization	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
furaltadone-3838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE240439_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289938
Hemorrhage	CTD Gene-Disease Associations	1.0	1.57924
BRD-K56616847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.585
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7198_KD_ICE1_SRP164752	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
internal globus pallidus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2732
positive regulation of exocytosis	GO Biological Process Annotations 2025	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45281
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
intermediate tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11098
regulation of exocytosis	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.861798
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_17408_KO_Rag2_SRP092590	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.86298
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.352
portal hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.825358
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33237
GTPase activity	GO Molecular Function Annotations 2023	1.0	null
19549311-SuppTable2-MMLandPhenotype	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90941
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95302_1_v_4_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19705
Warburg micro syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47584
BRD-K96353852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17466
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.98535
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1778
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
BRD-K58795356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34135
Coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.862
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21636
SMC3	ENCODE Transcription Factor Targets	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12341
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66276
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48546
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
other organism membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.397811
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946819
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00059
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11385366-Table2.xlsx-DBP-Overlapped_Gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
novobiocin-342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.882841
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843464
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46897
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68994
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215928
Epithelial cell_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59881
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9123
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882007
BRD-K69048559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18107
ZEB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914111
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75991
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13611
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14191
other organism part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.397811
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Headache	CTD Gene-Disease Associations	1.0	1.03159
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874817
BRD-K95537020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82161
secretory vesicle	GO Cellular Component Annotations 2025	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56564
SKBR3	CCLE Cell Line Gene Expression Profiles	1.0	1.4103
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18646
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908952
Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87689
SKUT1	DepMap CRISPR Gene Dependency	1.0	3.68647
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11585
hsa-miR-1292	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-4665-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.41121
Perturb_14807_KO_Bhlhe40|Bhlhe41_SRP216680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.61769
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982171
BRD-K87126326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26559
BRD-K89837874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10899
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	-1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.86011
ethanol_rattus norvegicus_gpl341_gds2107	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83341
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.688
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4593
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20061
PMC7825356-8844261.f3.docx-182-ZNF562_ZNF562	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5677_KO_Pcgf1/Pcgf6_SRP269225	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.82201
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
release	GeneRIF Biological Term Annotations	1.0	null
single-organism membrane organization	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54936
GSE142994_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68008192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19108
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KATOIII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5836
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40632
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05149
BRD-A64761364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09652
H4K20me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907383
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.9137
colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.232836
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39207
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13879
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26783
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12212
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	1.0	1.23082
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KK-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23182
Perturb_11337_KD_Ankrd35_SRP214047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-1.10872
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.625
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hesperidin-2648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70976
mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LK2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61579
BRD-K80439500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03236
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.13754
BRD-K88924787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65283
serotonin-5633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Intercellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14706
Anteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59879
intracellular transport	GO Biological Process Annotations 2015	1.0	null
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.65882
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54079231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45625
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614571
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S12-ZNF384_DiffExprGene-Unnamed_1_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.96183
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14781
GSE160817_3_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
conserved	GeneRIF Biological Term Annotations	1.0	null
adipiodone-3111	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05276
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01441
SR-95639A-4977	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
myosin V binding	GO Molecular Function Annotations 2023	1.0	null
GSE111035,GSE111040_10_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96211
hsa-miR-2114	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43292
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883362
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43914
including	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MCF7_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138866
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34141
Perturb_14724_KO_Dicer_SRP082704	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.9906
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057886
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126561
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83188
Perturb_9614_KO_Rprd1b_SRP241887	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4079
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0152
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866417
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705173
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Liver_GSE13440_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Thiotepa_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126229
CAL120	DepMap CRISPR Gene Dependency	1.0	4.2968
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917096
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85822
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
MCF7_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149377
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920234
KALS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78345
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926997
vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413912
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96372
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07918
Supramolecular polymer	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38334
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
secretory granule membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01604
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
e21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.47364
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920468
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268482
TBP	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4538	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55604
enzyme binding	GO Molecular Function Annotations 2015	1.0	null
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046984
ISHIKAWA(HERAKLIO)02ER-	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
Cholestasis	CTD Gene-Disease Associations	1.0	1.24997
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58616
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.54658
17597811-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
HNF4A	ENCODE Transcription Factor Targets	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.876224
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48709
synaptic vesicle exocytosis	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15025
GSE128099,GSE128159_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19088
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10020235-Table_2.xlsx-Sheet1-GSE37301_RAG2_KO_VS_RAG2_AND_ETS1_KO_NK_CELL_DN_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14515
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16703
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.423
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37004
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48701
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057571
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.98719
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.731524
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7411-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K00010082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49052
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A48U-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116492,GSE116495_3_v_1_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null