association	dataset	threshold value	standardized value
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11B-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B cell activation	GO Biological Process Annotations 2025	1.0	null
10924_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.75294
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55275
BRD-K39773004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05265
GSE148269,GSE148273_0_v_1_arid4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19094
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X0-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886768
RABL6	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02727
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K75073699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48741
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68238
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27618
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18128
Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03638
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00251
RDES	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33979
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33775409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38591
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21262
H3K23ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3679-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Alveolar lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.186
BRD-K23637241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01672
CUX1	ENCODE Transcription Factor Targets	1.0	null
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09019
AP2B1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24951
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
D542MG	DepMap CRISPR Gene Dependency	1.0	2.86768
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14748
SYT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48702
GTF2B	ENCODE Transcription Factor Targets	1.0	null
IPCEF1	Pathway Commons Protein-Protein Interactions	1.0	null
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73154
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RHOT2	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16734_KO_Tnfrsf11a_SRP103818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.30481
SMC2	Pathway Commons Protein-Protein Interactions	1.0	null
10097_ZFP90_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.571908
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31948
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01242
WSUDLCL2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06746
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48229
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21213
hsa-miR-4774-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
superior parietal lobule, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991452
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
HA1E	DepMap CRISPR Gene Dependency	1.0	2.31823
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837187
PDS5A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K17128952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39976
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
iloprost-496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81063
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93X-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66537
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52406
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67002
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01982
BRD-K29726765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76623
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842998
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K47062996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07673
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63609
hsa-miR-4260	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
JHU022	DepMap CRISPR Gene Dependency	1.0	4.60961
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.995527
MCF7_Motesanib Diphosphate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161274
AKT1S1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4644	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HGS	Pathway Commons Protein-Protein Interactions	1.0	null
GSE182680,GSE182683_10_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE62843,GSE64371_2_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09681
ZNF282	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02961
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14336
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11358
BRD-K24815102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20058
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056273
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00141
CHP1	Pathway Commons Protein-Protein Interactions	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.2982
Perturb_70_KD_LINE1_ERP011233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.43261
ZWILCH	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HT-01A-61R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BB-74-RX30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330621
RABEP1	Pathway Commons Protein-Protein Interactions	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1832
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UNC93B1	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65818
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4801	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64155
BT474	CCLE Cell Line Gene Expression Profiles	1.0	1.40944
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854098
VAPA	Pathway Commons Protein-Protein Interactions	1.0	null
CPCN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91557
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34238
GAA	Pathway Commons Protein-Protein Interactions	1.0	null
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63021
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64804596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10392
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25135
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867457
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08812
mantle zone of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05277
NCI-H295 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.052
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73154
guanyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4207
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94499
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.98337
MCM2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19035
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.54475
A549_Vandetanib_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133791
MCF7_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131024
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deep layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14457
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33937
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61614
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CISD2	Pathway Commons Protein-Protein Interactions	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18999
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32838
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19417
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25879
Lung adenocarcinoma_LUAD_TCGA-97-A4M3-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16876
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20652606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26238
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.70662
PMC11347378-41375_2024_2357_MOESM4_ESM.xlsx-Fig_7A_S8A_public_RNA-seq_DEGs-TFDP1_KO_HAP_cells_Human_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01223
SNX13	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80605
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.9681
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0788
adrenal gland	HPA Tissue Protein Expression Profiles	-1.0	-1.11113
RAB33B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
patu8988s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05305
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.82399
Cardiofaciocutaneous syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65037
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43549
BRD-K75330923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36894
guanyl ribonucleotide binding	GO Molecular Function Annotations 2023	1.0	null
hsa-miR-3158-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.01746
BRD-K59638683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33503
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
flufenamic acid-2267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92284
LM-1685-207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.47512
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
SMAD2	Pathway Commons Protein-Protein Interactions	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420175
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	1.0	0.935718
LIN7C	Pathway Commons Protein-Protein Interactions	1.0	null
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	1.85795
mantle zone of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35817
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.843913
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.50083
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92817
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18598
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82226
RAB18	Pathway Commons Protein-Protein Interactions	1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901579
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-39-CW59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266123
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30565
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08962
hsa-miR-4677-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
regulation of small GTPase mediated signal transduction	GO Biological Process Annotations 2023	1.0	null
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14009
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587733
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ras protein signal transduction	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
No annotation - 2	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08914
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1791
Islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0283
TM9SF1	Pathway Commons Protein-Protein Interactions	1.0	null
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34547
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980367
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A5DX-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPHA2	Pathway Commons Protein-Protein Interactions	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926011
7251_RFFL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.567969
CRCGN017_MCF10A.WT.HP_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04885
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903044
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.805021
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33491
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063869
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5114
NCIH1734	CCLE Cell Line Gene CNV Profiles	-1.0	-2.42992
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDS5B	Pathway Commons Protein-Protein Interactions	1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9143
Subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26909
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC42BPB	Pathway Commons Protein-Protein Interactions	1.0	null
MDAMB453	CCLE Cell Line Gene Expression Profiles	1.0	2.73533
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88703
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17263
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63386
methyldopate-2940	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00208
SOX9	ChEA Transcription Factor Targets	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HCFC1	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK2_knockdown_90_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.4958
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.331439
Heart	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01365
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48592
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_JNJ-7706621_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151271
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02092
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03125
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929193
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920395
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3057
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949394
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.739
DFCI024	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30442
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871113
RAB21	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17163
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U343	DepMap CRISPR Gene Dependency	1.0	6.06585
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.4145
DCTN3	Pathway Commons Protein-Protein Interactions	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73611
HLE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.69106
MMAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94392
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular protein transport	GO Biological Process Annotations 2023	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10145
SFT2D3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20565
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12939
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71811
acebutolol-1493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
343_ANKRD52_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.705324
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85865817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65006
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824022
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07111
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48049
ChIP_THAP11_20581084	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09597
COG4	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11971
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0212
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36379
hsa-miR-942	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
HEC1A	Achilles Cell Line Gene Essentiality Profiles	1.0	1.7275
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38311
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
ion binding	GO Molecular Function Annotations 2015	1.0	null
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Serum Alanine Aminotransferase Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE157594_5_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GOSR2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63171
KLC2	Pathway Commons Protein-Protein Interactions	1.0	null
liminal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0538
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858179
SCFD2	Pathway Commons Protein-Protein Interactions	1.0	null
prenatal lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8048
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.502768
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403269
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3749_KD_NORAD_SRP149071	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.67815
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895035
MAX	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285028
PMC12695649-41588_2025_2389_MOESM2_ESM.xlsx-GATA6_RIME-_AsPC-1-Gene_Symbol_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40772
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.73938
EPS8L3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1629
STX4	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF709	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06976
HNF4A-19761587-HUMAN INTESTINAL CELL LINE CACO-2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981578
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029871
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.979772
NCIH1155_LUNG	CCLE Cell Line Proteomics	1.0	7.98418
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02249
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11804
A204	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.57687
XPOT	Pathway Commons Protein-Protein Interactions	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-61-EH59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240341
ABC1	DepMap CRISPR Gene Dependency	1.0	2.54042
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868121
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42826
hsa-miR-1279	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
GDI2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K03305572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82695
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79832
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04149
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940702
Perturb_2834_KD_ESR1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.1135
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0705
EXOC4	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-532-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50397
AP1G1	Pathway Commons Protein-Protein Interactions	1.0	null
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44906
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64675
STAT1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95569142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09292
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9443
GSE182854_2_v_0_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96103104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33893
ZFX_KO_GDS2718_151_mouse_hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22975
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42196
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66165
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-1.11113
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22459
RS411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17673
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47489
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JMURTK2	DepMap CRISPR Gene Dependency	1.0	2.28496
TAL1	ENCODE Transcription Factor Targets	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10654
ATP6V1A	Pathway Commons Protein-Protein Interactions	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
ULK3	Pathway Commons Protein-Protein Interactions	1.0	null
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.838645
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948179
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4672
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12746
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.740034
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	2.43089
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29809
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06795
ZFYVE1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327714
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04264
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.32934
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39411
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.73286
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00506
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04762
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
heart	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3200-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06164
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2128
hsa-miR-217	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Pancreatic duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
lomofungin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.56713
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rett Syndrome_frontal cortex_GSE6955	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.23754
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4116
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940097
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.929549
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959086
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05428
GTEX-SNMC-1326-SM-2XCFK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97356
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein localization	GO Biological Process Annotations 2025	1.0	null
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14003
hsa-miR-3170	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10272
MYC	ChEA Transcription Factor Targets	1.0	null
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07922
PMC12019345-41598_2025_98989_MOESM10_ESM.xlsx-Sheet_1-CCNE2_related_genes_AND_HNSCC_HNSCC_DDP_NOT_DDR_Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	4.74973
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1753
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06884
RAB5B	Pathway Commons Protein-Protein Interactions	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66989
BRD-K26127374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33185
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37258
AIDA	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51626
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.36138
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1151
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427992
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14096_KD_HMGN3_DRP007117	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43467
8842_TFCP2L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.615211
ARL2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0814
BET1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433374
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12552
BRD-K19387722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34721
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3536
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15634
PMC10153265-media-3.xlsx-BENPORATH_NANOG_TARGETS_v2023_1-STANDARD_NAME_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
A1207	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.62837
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2957
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368018
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841607
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06087
CASK	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67193
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1016
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59523
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42727
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3929	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95479
BRD-K07740919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44026
FOXA2	ENCODE Transcription Factor Targets	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851709
CADPS2	Pathway Commons Protein-Protein Interactions	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.119587
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36717
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0126-SM-48U1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2088
hsa-miR-509-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75094875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01859
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	1.0	1.56684
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.5158
SSTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42923
BRD-K78007953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75165
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39875
PIK3R1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45541
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13816
PMC12486367-Supplementary_Data2.pdf-68-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
STOML2	Pathway Commons Protein-Protein Interactions	1.0	null
TJP2	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2117	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16063
HCE4	DepMap CRISPR Gene Dependency	1.0	2.39264
BF-22-EP86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251678
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64532
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39083
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-GM12878_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850167
TLN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17506
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45322
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNMBP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42148
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	3.22992
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7922-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.57379
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00877
RAP1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K91148820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9429
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58142
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61562
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.55872
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10934
BRD-K98891210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64778
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579897
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37496
hsa-miR-3162-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NIHOVCAR3_OVARY	CCLE Cell Line Proteomics	1.0	4.70447
MAFK	ENCODE Transcription Factor Targets	1.0	null
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57123
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19444
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215147
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90108753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22564
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL4249 (PPP2R2B)	NURSA Protein Complexes	1.0	null
Adrenocortical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217244
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0696
BRD-K09137343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1232
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
natural killer cell differentiation	GO Biological Process Annotations 2025	1.0	null
SNX12	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22897
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442511
hsa-miR-3924	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33548
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991519
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.844624
hsa-miR-146b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85425
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42776812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13102
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tumorigenesis	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4384-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09598619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78952
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35564
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.94652
VPS26A	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82878
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36799
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69543414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13859
MTA3	ENCODE Transcription Factor Targets	1.0	null
COLO680N	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05192
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAB9A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14132
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68852
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43839
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08045
natural killer cell activation	GO Biological Process Annotations 2023	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06406
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.76339
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.31393
MAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75434
BRD-A05422420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08404
Edema	CTD Gene-Disease Associations	1.0	1.10069
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23915
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972968
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03789
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406426
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00217
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.921475
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22285
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210073
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920395
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10786
ar_21330406_lncap_lof_human_gpl570_gds4113	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.250236
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09337
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03659
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907027
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864877
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_3_TurboID_1hr_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K67353973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63385
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZW10	Pathway Commons Protein-Protein Interactions	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851745
BRD-K23499378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06398
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890359
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
RAB23	Pathway Commons Protein-Protein Interactions	1.0	null
MERO83	DepMap CRISPR Gene Dependency	1.0	8.92573
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23588
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14826
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4228
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0243
SIX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K33268483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15557
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4482
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66267
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59498
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909332
MET_knockout_261_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.97513
lingual gyrus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36804
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867585
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67682
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36098
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24138
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957931
BRD-A42579861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15804
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A73559168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23118
XPO7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33451
BRD-K12841150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3994
SNX4	Pathway Commons Protein-Protein Interactions	1.0	null
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8802
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402913
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18481
WASF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33414
A549_PHA-680632_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138769
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166184,GSE166185_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928727
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410624
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	0.961495
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997606
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217672
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00618
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97627
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63826
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LGR5	Pathway Commons Protein-Protein Interactions	1.0	null
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4456
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
PKN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38909
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USH1C	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02231
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19649
A549	BioGPS Cell Line Gene Expression Profiles	1.0	1.0603
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM21A	Pathway Commons Protein-Protein Interactions	1.0	null
RANBP17	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70752
HCV JFH-1_48Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.27224
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.29447
PPP3CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70549
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73154
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65631
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Meprednisone_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146223
NFATC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899772
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329373
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hydrolase activity, acting on acid anhydrides	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.60919
H3K79me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NSF	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37956
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861883
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M5-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.53765
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32259
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dang	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_CEP-33779_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111585
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397917
sanguinarine-2927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05504
SEPT10	Pathway Commons Protein-Protein Interactions	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE225141,GSE225143_2_v_3_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229518
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43585
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565423
CHD2	ENCODE Transcription Factor Targets	1.0	null
VTI1A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05322
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00233
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A3-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4756-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.08478
Lung squamous cell carcinoma_LUSC_TCGA-66-2727-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909049
hydrochlorothiazide-1906	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35713
SMEK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23623
BRD-K70039231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43246
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08728
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.81395
trichostatin A-5511	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1643
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.99212
TFRC	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K37929710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17699
GSE157282_0_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.267726
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3186
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4495	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
VAMP8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869069
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01861
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IQGAP3	Pathway Commons Protein-Protein Interactions	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48824
EXOC5	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K15794956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27317
BRD-K36515664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7301
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041331
Perturb_12992_KD_MAFB_SRP276044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.34842
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205448
BRD-K74040368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.428
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08858
TOV21G	CCLE Cell Line Gene Expression Profiles	1.0	1.64312
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6263
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33251
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.784845
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.70605
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.51513
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	2.18807
hsa-miR-4418	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.17022
BRD-K44341877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11297
hsa-miR-4639-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
CRCGN015_HEPG2_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2062
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45181
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25301
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15629
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24657
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.27507
BRD-K27953820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40713
NUP50	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN013_HEPG2_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1885
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16648
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21293
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.01286
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
BRD-K52863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10972
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26709
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51315
CSNK2A2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9985_KD_U2AF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.52481
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972356
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V7-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79688948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45962
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48452
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93842
ETS1	ChEA Transcription Factor Targets	1.0	null
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.21863
cone-rod dystrophy 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14243
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hydroxyzine-1941	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941042
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6513
Alzheimer's Disease_CNS - Brain - Hippocampus (MMHCC)_GSE1297	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.59582
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22983069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12502
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87856
BRD-K41899231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08596
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
OSC-20	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.833
BRD-K39449566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17434
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K09996575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04954
A549_PF-3845_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133391
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35227
STXBP3	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.09935
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
STXBP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
G-402	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.47096
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
PMC6742760-41467_2019_12079_MOESM10_ESM.xlsx-Data_S8-Supplementary_Data_8_Target_genes_of_FOXA1-bound_enhancers_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68272
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.84036
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.465
NFE2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pravadoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48181
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29196
NCIH1869	DepMap CRISPR Gene Dependency	1.0	5.00725
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RHEB	Pathway Commons Protein-Protein Interactions	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055857
Inflammation	CTD Gene-Disease Associations	1.0	1.31716
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-0.938603
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.11113
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14636
hsa-miR-4647	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74488
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.20299
metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K87258738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30997
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_down-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	2.99948
CCND1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41669
monorden-493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K58491882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48987
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOA	Pathway Commons Protein-Protein Interactions	1.0	null
Arrhythmogenic Right Ventricular Cardiomyopathy_Myocardial tissue_GSE4120	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.7848
WASL	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.91392
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0135
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A13210451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08312
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
FANCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21989
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4644
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07027
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06167
Brain - Anterior cingulate cortex (BA24)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-2.64928
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.026664
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81176
CTNND1	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34699
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51067
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29247
CREB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
hsa-miR-451b	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21769
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPT8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18965
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30265
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38452
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45724
HCC2218	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11746
thiethylperazine-6154	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93527
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.978852
ASH3	DepMap CRISPR Gene Dependency	1.0	5.61609
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08334
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01431
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79759
GSE156708_1_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36393312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13042
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05431
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.827847
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11112
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01
GTEX-Q2AH-1726-SM-3NB2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12024
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TKQ2-1826-SM-33HB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2253
PMC11143964-jciinsight-9-161356-s009.pdf-17-TBX2-AS1_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215086_3_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20475
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932054
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SCAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
A549_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143887
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35295
SEPT11	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.11205
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82774
ANXA5	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lymphocyte differentiation	GO Biological Process Annotations 2025	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36406
GTEX-PX3G-0226-SM-3NB2C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2852
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06898
decreased leukocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.902257
ritodrine-2635	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
TRIM	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58319
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06179
HNF4A	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-510	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
phenothrin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75126
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321538
NCI-H295R cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0788
GRIPAP1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE180982_1_v_0_mlst8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endometriosis_Endometrium_GSE7305	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.27465
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12789
BRD-K26704304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09674
STAT1	ENCODE Transcription Factor Targets	1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12083
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.78939
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.20178
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299991
THAP11-20581084-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40539
UCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62507
RAB5C	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatocarcinogenesis	DisGeNET Gene-Disease Associations	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1326-SM-2XCDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12799
USF1	ENCODE Transcription Factor Targets	1.0	null
raloxifene-388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYO7B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08161
MDAPCA2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78069
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9538
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5903_NUP93_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.31947
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53492
Pancreatic Ductal Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEx Heart 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-3.1135
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V1H	Pathway Commons Protein-Protein Interactions	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069245
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69785
MAP2K3	Pathway Commons Protein-Protein Interactions	1.0	null
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.121
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8908
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88555
hsa-miR-889	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
SNU668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66853
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.78752
BRD-A34842997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09326
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0171
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08065
COG3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53BP2	Pathway Commons Protein-Protein Interactions	1.0	null
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14614
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42896
hsa-miR-4768-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
SEPT7	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24259
hsa-miR-1178	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.538986
RMND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16076
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0781
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23753
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GLYR1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53419
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03195
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25696
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14934
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
cell-substrate adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.331342
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37401
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09019
CRCGN015_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0618
CAB39	Pathway Commons Protein-Protein Interactions	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054816
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
MTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33307
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49808
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	1.66221
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10555
KDM5B	ENCODE Transcription Factor Targets	1.0	null
PMC12658036-41598_2025_25964_MOESM5_ESM.xlsx-Sheet1-Supplementary_Table_1_The_list_of_546_proteins_specific_to_pLV3-CMV-AR-TurboID_H2O2_group_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827919
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.931273
Perturb_6014_KD_FUS_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20143
inner CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05235
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.865007
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.555938
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77950699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62766
BRD-K96758498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55716
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
HCC1143	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62835
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03086
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LRRK2_mutant_32_GDS4400	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.37646
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PIN1	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
TE5	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05132
CREB1	ENCODE Transcription Factor Targets	1.0	null
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51067
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28289
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05644
BRD-K03770502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27218
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478797
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7713
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2225
MAPKAPK3	Pathway Commons Protein-Protein Interactions	1.0	null
PITPNA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11209
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4711-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65777
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.30676
CNN2	Pathway Commons Protein-Protein Interactions	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
EIF2B4	Pathway Commons Protein-Protein Interactions	1.0	null
TOV-112D	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.17897
flucytosine-5289	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912981
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.986228
HMEL	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25142
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A95683194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45352
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83604
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61507
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935355
RCM1	DepMap CRISPR Gene Dependency	1.0	3.6591
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924252
regulation of lipoprotein metabolic process	GO Biological Process Annotations 2023	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10194_KD_TAF1_SRP149373	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PDCD4	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RD	DepMap CRISPR Gene Dependency	1.0	2.50466
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1437	CCLE Cell Line Gene Expression Profiles	1.0	1.4014
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A427	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59184
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.98213
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75569
GTEX-XMK1-2226-SM-4B673	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00209
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220755
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972284
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82839
FOXA1	ENCODE Transcription Factor Targets	1.0	null
MAPK8	Pathway Commons Protein-Protein Interactions	1.0	null
CCND1	ChEA Transcription Factor Targets	1.0	null
THAP11-20581084-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
trichostatin A-6671	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35665
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41573
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00685
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4510	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF559	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29003
gtp binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K47716724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31494
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03136
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal T cell morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.29843
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MC-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-198	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KB-77-BA46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206525
JVM2	CCLE Cell Line Gene Expression Profiles	1.0	1.94384
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23439
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22948
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05445
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2368
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62985
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T cell differentiation	GO Biological Process Annotations 2023	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891548
PD-128907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11003
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900556
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.33256
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16357
VAMP3	Pathway Commons Protein-Protein Interactions	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.49967
hsa-miR-510	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85359206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0485
regulation of protein modification process	GO Biological Process Annotations 2023	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8185
artemisinin-7247	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
binding	GO Molecular Function Annotations 2015	1.0	null
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations	1.0	0.314454
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00762
protein stabilization	GO Biological Process Annotations 2023	1.0	null
A549_Iniparib_10µM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137881
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4653
SYM-2206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49211
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08457
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OE-31-YC41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219508
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.72112
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19788
BRD-K53612850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0643
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37595074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0738
RANBP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76976010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58804
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04165
PGAM5	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFAIP8	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17423
TRAPPC3	Pathway Commons Protein-Protein Interactions	1.0	null
bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
protein transport	GO Biological Process Annotations 2023	1.0	null
2313287	CCLE Cell Line Gene Expression Profiles	1.0	1.81917
BRD-K49745710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17139
NPFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40719
ATP6V1C1	Pathway Commons Protein-Protein Interactions	1.0	null
Subparafascicular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61562
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.51359
SQ1_LUNG	CCLE Cell Line Proteomics	1.0	2.25501
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2011
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34541
GSE185944_5_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKMEL1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72135
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36787
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07073
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5335_KO_Myc/Mycn_ERP009787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69851
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4575
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5561
KYSE510_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	2.26636
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
patu8988t	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	1.92099
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pentoxifylline-1444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04096
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985592
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55946
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14787
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07217
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196962_2_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16424
Heschl's gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35246
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08345
BRD-K96641838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4359
Ectomesenchymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
NCAPG	Pathway Commons Protein-Protein Interactions	1.0	null
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58678
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skeletal system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.028652
H4K5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98481
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217069
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46944
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32716
CACYBP	Pathway Commons Protein-Protein Interactions	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.385534
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01497
treatment	GeneRIF Biological Term Annotations	1.0	null
SDF4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24325
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218960_0_v_1_nrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10239
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K34737616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11399
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
candidate	GeneRIF Biological Term Annotations	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
regulation of protein lipidation	GO Biological Process Annotations 2025	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.16654
BRD-K90697691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16678
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226113
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.57886
32D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTN2	Pathway Commons Protein-Protein Interactions	1.0	null
RAB3GAP1	Pathway Commons Protein-Protein Interactions	1.0	null
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41649
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05795
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22297
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	2.01039
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.147167
BRD-K36468214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86497
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2973
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2176
PMC6683136-41598_2019_47363_MOESM2_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1-AS1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABR	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K44946060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19823
trazodone-2379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
EIF2B1	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84151
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850167
hsa-miR-581	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
nucleoside-triphosphatase activity	GO Molecular Function Annotations 2015	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39051
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01143
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15499
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7994-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1553
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.141
hsa-miR-1236	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
BRCA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K45712538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01881
CAOV3	CCLE Cell Line Gene Expression Profiles	1.0	2.01651
BRD-K99681648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10686
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22451
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.08837
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835102
STARD5	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SNAP23	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125403_7_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381972
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.16512
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-153	TargetScan Predicted Conserved microRNA Targets	1.0	0.020071
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06792
ATP6V1E1	Pathway Commons Protein-Protein Interactions	1.0	null
LIVF001-011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05729
FE-69-HJ93_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24558
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
PMC12678582-41698_2025_1153_MOESM5_ESM.xlsx-Sheet1-Common_genes_between_OVCA420-ZNF217_and_MCF7_157_965_1122_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.06804
STX5	Pathway Commons Protein-Protein Interactions	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6577
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998071
GSE211128_3_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12359
WASF2	Pathway Commons Protein-Protein Interactions	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
layer 5 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58142
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01785
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0156
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42235
PMC3371315-NIHMS350140-supplement-13.xls-MCF7-T47D-SK-453_Up_Common_xls-Supplementary_Table_6_Luminal_Signature_Genes_increased_in_all_four_cell_lines_MCF7_T47D_MB-453_SKBR3_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of protein modification process	GO Biological Process Annotations 2025	1.0	null
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.74831
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03559
PTK2	Pathway Commons Protein-Protein Interactions	1.0	null
FNBP1L	Pathway Commons Protein-Protein Interactions	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
tremorine-6273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NAPG	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K50851442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13704
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30457
GSE173910,GSE173917_1_v_0_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25553
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.718471
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7221
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18132
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25059
anteroventral part of alar thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43839
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89527
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924346
RAB14	Pathway Commons Protein-Protein Interactions	1.0	null
wortmannin-389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
DIDO1	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osseous plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
STX16	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4318	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06633
SB-94-ZA83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283214
SCAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07217
Weight Loss	CTD Gene-Disease Associations	1.0	1.27471
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22476
BRD-K46161579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49291
SEPT2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07602
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961342
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21961
Pelvic fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67407
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0565
MOLM-13	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.22345
BRD-K54100265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52012
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0264
BRD-K25203350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10597
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4852
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.52299
hsa-miR-1205	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
PTP4A1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44415
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33855
PLEKHA2	Pathway Commons Protein-Protein Interactions	1.0	null
rara_21911359_f9_teratocarcinoma_lof_mouse_gpl1261_gds4294	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.18851
CHLA10	DepMap CRISPR Gene Dependency	1.0	7.27631
L363	CCLE Cell Line Gene Expression Profiles	1.0	2.27067
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65561
EXOC8	Pathway Commons Protein-Protein Interactions	1.0	null
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254001
AP1M2	Pathway Commons Protein-Protein Interactions	1.0	null
PSEN1	Pathway Commons Protein-Protein Interactions	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.18671
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-8569-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28112
NFYA	ENCODE Transcription Factor Targets	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.883797
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.73255
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RINT1	Pathway Commons Protein-Protein Interactions	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4762
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900885
ZNF384	ENCODE Transcription Factor Targets	1.0	null
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
20460542-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SARS-BatSRBD_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.54977
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16967
Dendritic growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
lateral part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04882
A2058_SKIN	CCLE Cell Line Proteomics	1.0	2.43236
biological_process	GO Biological Process Annotations 2015	1.0	null
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26684
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6239_PFDN4_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.544391
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A71590475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12769
KIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18779
FAM129B	Pathway Commons Protein-Protein Interactions	1.0	null
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32894
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.26305
EBF1	ENCODE Transcription Factor Targets	1.0	null
VPS35	Pathway Commons Protein-Protein Interactions	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.916765
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49325
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209352
Uterus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.66956
regulation of small GTPase mediated signal transduction	GO Biological Process Annotations 2025	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.44162
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916607
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00059
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.70147
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07728
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991562
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825869
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.857695
BRD-K32856496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22093
ARHGEF10L	Pathway Commons Protein-Protein Interactions	1.0	null
1274_CCDC28B_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.571365
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907576
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.54279
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Teratogenesis	CTD Gene-Disease Associations	1.0	1.03939
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.36738
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6974
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAPK1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.934204
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.784101
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K84178323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.86335
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4607_KD_H2A.Z_SRP345495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.10702
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972553
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Y-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5416
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3192
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07728
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985259
SRF_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52681
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
BRD-K60782883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15696
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2526
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38099
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17952
OVCAR8	BioGPS Cell Line Gene Expression Profiles	1.0	0.868488
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7368-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4461	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Pancreatic Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SCFD1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A5OB-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0168
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16459
CORL51	CCLE Cell Line Gene CNV Profiles	1.0	1.34855
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894186
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384039
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.6683
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922368
GTEX-XUYS-0226-SM-47JX1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05652
SNF8	Pathway Commons Protein-Protein Interactions	1.0	null
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31849
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12172
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ILKAP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
obesity	GWASdb SNP-Phenotype Associations	1.0	1.12851
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87215
RAB6A	Pathway Commons Protein-Protein Interactions	1.0	null
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.40173
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31478
RFX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37659
TAF1	ENCODE Transcription Factor Targets	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0383
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72792
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57385
GATA3-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K55164454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59224
BRD-K90046234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25554
RS4-11	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.09732
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051103
hsa-miR-3120-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7608-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85474153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28298
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56202
EIF2B5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885952
Pancreatic juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
SWAP70	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14225
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V0D1	Pathway Commons Protein-Protein Interactions	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913838
VDR	ChEA Transcription Factor Targets	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3140-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Metacyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
8855_TFPT_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.01965
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1565
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3462
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.901709
GSE182181_1_v_0_ricolinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSUNHL	DepMap CRISPR Gene Dependency	1.0	4.76902
H3K36me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04182
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.84374
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A15330900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66984
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.456271
MFE280	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63298
ANXA11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29408
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLD1	CCLE Cell Line Gene Expression Profiles	1.0	1.50098
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAN	Pathway Commons Protein-Protein Interactions	1.0	null
PLEKHF2	Pathway Commons Protein-Protein Interactions	1.0	null
TAP2	Pathway Commons Protein-Protein Interactions	1.0	null
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92773
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452033
CRCGN008_HEPG2_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60625
FOSL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K50068274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70484
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74833
Perturb_15396_KD_CSN5_SRP316687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.8307
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36652
anion binding	GO Molecular Function Annotations 2015	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.528116
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891489
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22084
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GNB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.937716
MINO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65517
EPS8L2	Pathway Commons Protein-Protein Interactions	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone-369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS766T	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05387
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36023
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3366
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28937
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38872
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958136
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03778
CREB1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71539
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824249
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4938-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06317
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE82032_3_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04105
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-1126-SM-4GIAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970474
Lung adenocarcinoma_LUAD_TCGA-05-4396-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20065789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08067
PPP2CA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.49399
BRD-K17062413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19126
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.997408
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4677-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942578
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1_01_141	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.995
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.937577
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282913
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22385
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47447
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.578651
STAM	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-6143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84633
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.19691
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03453
MAFK_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
an3ca	HPA Cell Line Gene Expression Profiles	-1.0	-1.2941
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.35572
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15334
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23795
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81313
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.665203
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8777
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE221932,GSE222115_0_v_1_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20665
SETDB1_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142592
EPS8	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K61072684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15109
Lung squamous cell carcinoma_LUSC_TCGA-77-6844-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976326
Sepsis_Splenocyte_GSE4479	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.82985
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05543
regulation of lipoprotein metabolic process	GO Biological Process Annotations 2025	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BLOC1S6	Pathway Commons Protein-Protein Interactions	1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243385
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein stabilization	GO Biological Process Annotations 2025	1.0	null
GTEx Heart 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-3.69149
BACH1	ENCODE Transcription Factor Targets	1.0	null
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215301
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979129
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069967
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33351
BRD-K67007076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23391
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93243
SAP30	ENCODE Transcription Factor Targets	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88684430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14983
STX18	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57299
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40904
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVMIU	DepMap CRISPR Gene Dependency	1.0	3.49314
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A499-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38376
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.57403
regulation of protein lipidation	GO Biological Process Annotations 2023	1.0	null
Small GTPase superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Measles Chicago-1_6Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51998
PDCD6IP	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-6.10713
ELMO3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27309
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18206
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32211
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.282926
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10283
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.8076
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP6V1C2	Pathway Commons Protein-Protein Interactions	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48405
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1028
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06237
BRD-K94514173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49491
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50389
UBTF	ENCODE Transcription Factor Targets	1.0	null
SIGMAR1	Pathway Commons Protein-Protein Interactions	1.0	null
RACGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.343698
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-HVC_612_gene_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
DUSP3	Pathway Commons Protein-Protein Interactions	1.0	null
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
BRD-K01716842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16479
A549_Tofacitinib_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131069
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.48922
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79752
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PTPN1	Pathway Commons Protein-Protein Interactions	1.0	null
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02527
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858589
SYNJ2BP	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15705
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.036
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPSCR1	Pathway Commons Protein-Protein Interactions	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Y-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
B cell activation	GO Biological Process Annotations 2023	1.0	null
TXLNA	Pathway Commons Protein-Protein Interactions	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845408
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867247
GSE148066,GSE157787_9_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31991
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.11113
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15912
BRD-K43535770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14689
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61194
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48434
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alanine Aminotransferase Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8114
AGK	Pathway Commons Protein-Protein Interactions	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64653
CAMA1	CCLE Cell Line Gene Expression Profiles	1.0	1.51468
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31855
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.66653
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AP1S2	ChEA Transcription Factor Targets	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHG3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12862344-can-24-4809_supplementary_data_s1_suppsd1.xlsx-Correlation_values_from_FigS6A-Supplementary_Data_1_Genes_with_high_correlation_values_with_PRDM16_from_Figure_S6A_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32522318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70129
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RALB	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92817
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46N-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36243
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69272
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14792
PLA2G4A	Pathway Commons Protein-Protein Interactions	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16113
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2152
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1625
DIAPH1	Pathway Commons Protein-Protein Interactions	1.0	null
HPAFII	DepMap CRISPR Gene Dependency	1.0	5.97391
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1985
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33455
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
VPS16	Pathway Commons Protein-Protein Interactions	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29203
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37961
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77009
Perturb_2836_KD_MDC1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.11593
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827352
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914353
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18252
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01828
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.995691
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDHK4	Kinase Library Tyrosine Kinome Atlas	1.0	98.43
K562_AZ 960_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148788
TEK_knockdown_122_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.7639
VPS18	Pathway Commons Protein-Protein Interactions	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.71609
VPS33A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8357
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85604751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38589
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.306
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.01264
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86707
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
KIF2A	Pathway Commons Protein-Protein Interactions	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588503
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20915
PMC6858560-NIHMS1538530-supplement-Supplementary_Tables.xlsx-Supplementary_Table_22-Supplementary_Table_22_Aberrant_Splicing_Events_in_TET2_SRSF2_co-mutated_AML_Patients_from_the_Beat-AML_cohort_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17070436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14568
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977414
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40137
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99674
BRD-K00350773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98763
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11971
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260012
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07847
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.177458
KC-17-YN77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282582
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.51391
hsa-miR-185	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE125219,GSE125221_5_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
FLOT1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
TOM1	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15576
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92817
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERLIN1	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGAP8	Pathway Commons Protein-Protein Interactions	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4712
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.13007
hsa-miR-4668-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849086
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55855103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55265
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
IST1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26619
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40729
Lung squamous cell carcinoma_LUSC_TCGA-18-3414-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907655
SHB	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN013_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37622
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74743
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.62826
ATG5	Pathway Commons Protein-Protein Interactions	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0173
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59013
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-13-CREB3L4_CREB3L4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972113
Brain Lower Grade Glioma_LGG_TCGA-HW-7493-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
RIF1	Pathway Commons Protein-Protein Interactions	1.0	null
werirb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49903
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26655
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49672
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RALA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZD-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00951
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.28159
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4348
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2215
Carpenter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
hsa-miR-574-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMED10	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07986
BCAP31	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921648
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0378
EXOC6	Pathway Commons Protein-Protein Interactions	1.0	null
RHOT1	Pathway Commons Protein-Protein Interactions	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
Retinoblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6013-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15683
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAG1	Pathway Commons Protein-Protein Interactions	1.0	null
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38921
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983682
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32575
POU2F2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vorinostat_homo sapiens_gpl570_gse34880	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LY-294002-1661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25457
VPS28	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4475	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
MTOR	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5644
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07728
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7402-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99764436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0974
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48728
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28527
Lung squamous cell carcinoma_LUSC_TCGA-21-1071-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPRC5A	Pathway Commons Protein-Protein Interactions	1.0	null
CHMP2A	Pathway Commons Protein-Protein Interactions	1.0	null
DC-43-KF54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306216
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KATOIII_STOMACH	CCLE Cell Line Proteomics	1.0	3.63668
dextromethorphan-6300	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HEC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.4341
CRCGN010_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48434
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16115
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78856
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.654509
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10418
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XBP1_01_203	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6077
PMC5390115-mmc7.xlsx-DE_Lists-H1-ECs_Experiment_2_H1-EC2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
Aspartate Aminotransferase Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
hupt4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
2899_TASOR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.698101
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52767
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50939
P3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40424
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.321201
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965582
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.16419
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.01169
DANG_PANCREAS	CCLE Cell Line Proteomics	1.0	2.20205
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RSF1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0053
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46908
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28927
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841718
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K43495666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21969
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0YX-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66202
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.912721
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74971
7657_SARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.520191
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GOSR1	Pathway Commons Protein-Protein Interactions	1.0	null
TBC1D4	Pathway Commons Protein-Protein Interactions	1.0	null
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0391
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
EHD1	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K88344082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.242
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1CB	Pathway Commons Protein-Protein Interactions	1.0	null
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14699
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929193
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56843
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10928
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7902
ERLIN2	Pathway Commons Protein-Protein Interactions	1.0	null
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17548
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0156
MCF7_WP1066_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144061
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08458
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07499
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16759
GTEX-S4P3-1526-SM-3K2AV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06917
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880147
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42124
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1869 (TRIP4)	NURSA Protein Complexes	1.0	null
301_ANAPC10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.793729
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.65572
SF767	Achilles Cell Line Gene Essentiality Profiles	1.0	1.90121
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17763
JHH4_LIVER	CCLE Cell Line Proteomics	1.0	2.26636
COPE	Pathway Commons Protein-Protein Interactions	1.0	null
SEC31A	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856354
Brain Lower Grade Glioma_LGG_TCGA-HT-7485-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12812
Actinic keratosis_Skin tissue_GSE2503	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.6466
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28803
BRD-A77181042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90104
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F2-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
small gtpase mediated signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6996923-elife-46981-supp4.xlsx-KO_Up_Only_Vs_OCT4-Column_ID_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GRB2	Pathway Commons Protein-Protein Interactions	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86215
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887804
Legius syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
RAB5A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GSE171177,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CENPV	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07087
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29375
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.847983
GTEX-XV7Q-2326-SM-4BRVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925428
CBX3	ENCODE Transcription Factor Targets	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K51566146	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32352
Mo-T	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.32315
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22288
internal globus pallidus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63386
NCIH1734	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61345
IC-05-AW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285967
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59292
STARD10	Pathway Commons Protein-Protein Interactions	1.0	null
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.325
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular transport	GO Biological Process Annotations 2015	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54943
U2OS_BONE	CCLE Cell Line Proteomics	1.0	3.01328
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
UO31	BioGPS Cell Line Gene Expression Profiles	1.0	0.982028
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4276
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04655
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18642
CRCGN017_MCF10A.TP53.M_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2258
GA-28-SS67_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340706
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112124
BRD-K05789358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47817
RAB35	Pathway Commons Protein-Protein Interactions	1.0	null
EPAS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8078
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4005
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4729	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.88367
SCP2	Pathway Commons Protein-Protein Interactions	1.0	null
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K57756744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34487
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
LRCH4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02962
KNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.822
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69269694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43415
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07004
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307295
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08372
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13409
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33505770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53157
MEGF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85287
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2759-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC2	ChEA Transcription Factor Targets	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976786
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16111
BRD-K55053106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05556
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SRF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERGIC1	Pathway Commons Protein-Protein Interactions	1.0	null
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
Poisoning	CTD Gene-Disease Associations	1.0	1.19312
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841392
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64655
B cell differentiation	GO Biological Process Annotations 2025	1.0	null
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS37B	Pathway Commons Protein-Protein Interactions	1.0	null
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06668
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
RAC1	Pathway Commons Protein-Protein Interactions	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71824
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5114
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63283
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11103890-mmc3.xlsx-ZZZ3_interactors_ESC-2-Gene_names_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4428	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
MGH-U4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961779
BRD-K54370483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94442
TRAPPC4	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38646
SKRC31	DepMap CRISPR Gene Dependency	1.0	3.17886
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880339
UW228	DepMap CRISPR Gene Dependency	1.0	6.54017
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC30A9	Pathway Commons Protein-Protein Interactions	1.0	null
8-M-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4639
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0535
PPP1R7	Pathway Commons Protein-Protein Interactions	1.0	null
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06487
BRD-K04939366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00257
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68871
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.849373
ANXA9	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-885-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.506334
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23228
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.4871
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5668
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38637
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07834
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VL-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-16	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.95936
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490955
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15954
GSE57871_5_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66225
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36170758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11066
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08447
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03151
BL1327 (FOXO3)	NURSA Protein Complexes	1.0	null
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_642_KD_FASTKD1_SRP299834	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.00581
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-encode-consensu_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21841
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intralaminar nuclei of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06584
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.904152
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68647
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-15a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Caov-3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.06308
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81753
CHP-212	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.92149
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4535	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33237
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKP1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387781
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57033
Pollen tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
Lung adenocarcinoma_LUAD_TCGA-55-7903-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64155
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4788	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62574
HCMV_TB40E_24Hour_19951172_GSE14816	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.00766
hsa-miR-4446-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
BRD-K42732309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15585
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19179
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40236
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20618
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.82076
VPS4B	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HW-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT11	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K35953312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20916
protein homodimerization activity	GO Molecular Function Annotations 2025	1.0	null
STX3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K19264579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10857
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	3.24951
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLIN3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2699
Lung squamous cell carcinoma_LUSC_TCGA-60-2710-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5517-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.76863
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30658
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65932559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15188
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.953023
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vagina	HPA Tissue Protein Expression Profiles	1.0	1.70147
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13824
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874777
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9021
protein localization	GO Biological Process Annotations 2015	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2023	1.0	null
BRD-K41993678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05841
BRD-K60716223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19775
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48728
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983553
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16759
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27782
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44992
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65F-01A-21R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849086
GSE241108_1_v_0_sulfasalazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988688
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.953212
PRKAR2A	Pathway Commons Protein-Protein Interactions	1.0	null
SNX1	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAP2K4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04075
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28993
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40051
cefotaxime-1389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03628
intermediate stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05578
HEC1A	CCLE Cell Line Gene Expression Profiles	1.0	1.45463
SCLC21H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6352
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
spleen hypoplasia	MGI Mouse Phenotype Associations 2023	1.0	null
BT483	CCLE Cell Line Gene Expression Profiles	1.0	2.05152
SRSF9_02_90	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59346
BRD-K47848960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59505
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61074
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32103
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983639
IRF4	ENCODE Transcription Factor Targets	1.0	null
LOXIMVI	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.18547
BRD-K56015010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05935
BRD-K20798215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45926
RRAS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49549
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98695
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09091
BRD-K89278382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85685
PANC0813	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0338
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21681
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
XC-88-ZM66_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279696
Contractile vacuole complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17817
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.907489
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MAPK14	Pathway Commons Protein-Protein Interactions	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864088
Rectum adenocarcinoma_READ_TCGA-DY-A1DC-01A-31R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.56828
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PLEKHH1	Pathway Commons Protein-Protein Interactions	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.10175
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLTA	Pathway Commons Protein-Protein Interactions	1.0	null
RAB2A	Pathway Commons Protein-Protein Interactions	1.0	null
SKMM2	DepMap CRISPR Gene Dependency	1.0	2.37468
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849273
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04829
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TX-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.15495
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75773
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86391
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MYOF	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K53443165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16878
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.849645
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5XZ-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
zimeldine-2012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3697
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996967
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838282
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
guanyl ribonucleotide binding	GO Molecular Function Annotations 2025	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K20875709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19895
FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48145537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57858
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
PDCD6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-501-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
thiamine-1744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Joubert syndrome 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIFC1	Pathway Commons Protein-Protein Interactions	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNCA_KO_GDS4153_444_mouse_Cerebellum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897877
BRD-K49910674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43032
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOOK1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898481
hsf1_19179333_rko_colon_carcinoma_lof_human_gpl6244_gse12762	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.09342
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36864
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04983
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
MCF7_Epothilone A_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116989
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protein transport	GO Biological Process Annotations 2025	1.0	null
PMC5404927-elife-24463-supp1.xlsx-1b_ERM_proteome-Gene_names_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0093
IRF3	ENCODE Transcription Factor Targets	1.0	null
VPS25	Pathway Commons Protein-Protein Interactions	1.0	null
zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.065801
BRD-A03898562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35737
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25699
HL-60	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.83426
LN-18	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.9571
ASPC1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.58678
Lung squamous cell carcinoma_LUSC_TCGA-85-7844-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33148
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438518
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96362
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836344
EHD4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34124
biological regulation	GO Biological Process Annotations 2015	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5364-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBX1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994456
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ARHGAP35	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55984
Perturb_14087_Mut_LST8_SRP330127	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_NANOG_targets_Boyer_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877209
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.075
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259186
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.833022
BRD-K40646662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42131
BCAP29	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39326623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59893
naltriben-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36617
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.11113
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14448
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07847
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929394
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDGFRB_knockdown_114_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.79883
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07878
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
hsa-miR-4662b	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
T cell differentiation in thymus	GO Biological Process Annotations 2025	1.0	null
protein transport	GO Biological Process Annotations 2015	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.841683
BRD-K14520048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53766
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0277
SPC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12631
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
IPO13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41605
GSE169152_5_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9642
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.68645
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22198
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL23	CCLE Cell Line Gene CNV Profiles	1.0	1.4174
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-1289	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75931
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68527
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03828
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
patu8902	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68438316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13026
SW579	DepMap CRISPR Gene Dependency	1.0	2.73333
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
focal adhesion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.333979
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21152
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32563
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEC	Pathway Commons Protein-Protein Interactions	1.0	null
U87	BioGPS Cell Line Gene Expression Profiles	1.0	1.34544
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982769
ATP6V0C	Pathway Commons Protein-Protein Interactions	1.0	null
CAL120	DepMap CRISPR Gene Dependency	1.0	5.67993
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24378
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32418
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12215
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34752
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4670-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064556
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0326-SM-46MVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887468
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836344
PRKAB1	Pathway Commons Protein-Protein Interactions	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAB43	Pathway Commons Protein-Protein Interactions	1.0	null
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53409
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54418
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74071
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_9368_OE_NRG1_SRP201884	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38278
EXOC7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BALL-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.47047
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23064
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4504	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84419
CPNE3	Pathway Commons Protein-Protein Interactions	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66248685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23306
KIF20B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SETD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10319
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45645
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9286
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_PFI-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141413
KYSE450	Achilles Cell Line Gene Essentiality Profiles	1.0	1.15158
HCT15	CCLE Cell Line Gene Expression Profiles	1.0	1.5046
IQGAP2	Pathway Commons Protein-Protein Interactions	1.0	null
TXLNG	Pathway Commons Protein-Protein Interactions	1.0	null
p2 part of the zona limitans core population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08286
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73492
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18642
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMH2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94841
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE144346_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.00225
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.82431
GOLIM4	Pathway Commons Protein-Protein Interactions	1.0	null
VPS29	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UCHL3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08313
TRIB1_KO_GDS2944_555_mouse_Macrophages	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6521
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.944135
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29248
meteneprost-7500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.13793
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05432
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15665
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851868
Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15251
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32179
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2170 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05273
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09442
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79055
SPIB	JASPAR Predicted Transcription Factor Targets	1.0	null
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36224
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.8442
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RUSQ-2026-SM-4GIAK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885018
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	2.96121
496100397_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07386
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25457
loxapine-2016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Costunolide_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163889
EPB41L2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27341
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12788
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64299311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29598
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05543
ZWINT	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06377
7734_SEC13_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.639034
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0883
Perturb_13662_KD_E2F1_SRP225180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.18512
CRCGN015_HEPG2_48H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01356
T cell differentiation in thymus	GO Biological Process Annotations 2023	1.0	null
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85845
VAV2	Pathway Commons Protein-Protein Interactions	1.0	null
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05877
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36728
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16235
COPZ1	Pathway Commons Protein-Protein Interactions	1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16244
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15473
BRD-K58762810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24335
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rab protein signal transduction	GO Biological Process Annotations 2015	1.0	null
22RV1	CCLE Cell Line Gene Expression Profiles	1.0	1.41225
OVCAR8	Achilles Cell Line Gene Essentiality Profiles	1.0	1.54441
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01960204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77297
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A68949340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10357
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23338
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92817
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-0.917595
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75773
ZFPL1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26742
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22975
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.82637
NR2F2	ENCODE Transcription Factor Targets	1.0	null
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05566
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_3_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
cefaclor-2843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3119	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Perturb_15748_KO_Thap11_SRP065965	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.87589
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.316
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74413
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64269
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
BLOC1S5	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8
Central conducting lymphatic anomaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05173
aceclofenac-7029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.22948
betulin-7454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56005
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02337
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7410-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SGK3	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
BRD-K54264597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02837
hsa-miR-3915	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
hsa-miR-4475	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17708
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41103
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875187
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.68146
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epirizole-1681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03653
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
k562clones	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07107
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01435
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89712
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ENHANCED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Dasatinib_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175971
BRD-K61386375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05957
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW780	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.80153
REST	ENCODE Transcription Factor Targets	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14557
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878662
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EW22	DepMap CRISPR Gene Dependency	1.0	2.26416
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VPS36	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K15273135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27161
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920395
hsa-miR-4648	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214765
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293255
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04585
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21035
WholeBlood	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12945
BRD-K53257307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77466
OSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61781
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.675353
DNM2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A74615450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71018
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bone marrow	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KIF5B	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21942
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4553
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.207
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11385078-jciinsight-9-172336-s278.xlsx-Sheet1-Supplementary_Table_4_A_Differential_proteins_from_AA_BLCA_and_EA_BLCA_tissues_using_mass_spectrometry_based_proteomics_analysis_from_Figure_1C_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.19943
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830136
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERGIC3	Pathway Commons Protein-Protein Interactions	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8063_KD_FOXA1/FOXA2_SRP327811	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.60145
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7065-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09155
H6PD_KO_GDS3195_602_mouse_Skeletal muscle - Soleus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63549
RPS6KA5	Pathway Commons Protein-Protein Interactions	1.0	null
NPBWR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00537059
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Prednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157917
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.73277
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.256561
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5151-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842125
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94901
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65J-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.992577
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MMP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16906
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	JASPAR Predicted Transcription Factor Targets	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78966
SRSF9_02_13	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60998
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30281
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44734
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61283064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26663
BRD-K74150320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1299
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12213
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4731-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05593
TOV21G	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.19652
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854122
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885708
BRD-K45974539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13325
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenal cortex cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9914
OSBP	Pathway Commons Protein-Protein Interactions	1.0	null
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CDIPT	Pathway Commons Protein-Protein Interactions	1.0	null
BAZ1B	Pathway Commons Protein-Protein Interactions	1.0	null
PPP5C	Pathway Commons Protein-Protein Interactions	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42873
hsa-miR-31	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
RAP2B	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850167
BRD-A02799884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40224
ARCN1	Pathway Commons Protein-Protein Interactions	1.0	null
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0621
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48197
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4482
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.91961
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2784
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48263
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53046137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59341
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06687
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18312
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849086
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82878
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-85-YK41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.749908
CRCGN009_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16593
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43367
USP9X	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05902
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953881
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2193
KLC1	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
ribavirin_homo sapiens_gpl570_gds4391	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K32084247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21843
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46908
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54503
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24843
GTEX-WEY5-1926-SM-3GIL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49567
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61046
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49048
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVI1-22308434-SKOV3-HUMAN-OVARY-OVARIANCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828768
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51248
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37586
phenylpropanolamine-1602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3682-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23348
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07073
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSU1	Pathway Commons Protein-Protein Interactions	1.0	null
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4273	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870507
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867741
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33563
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40662
BRD-K80021597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05235
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6165
T cell differentiation	GO Biological Process Annotations 2025	1.0	null
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.73256
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00093
RMND1	Pathway Commons Protein-Protein Interactions	1.0	null
HCMV_24Hour_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.1111
Perturb_12244_KD_KDM5A_SRP325972	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16389
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
BRD-K20079620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35448
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15577
BRD-K91620436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07398
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clozapine-1654	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12919
BRD-K88647644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0854
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of Ras protein signal transduction	GO Biological Process Annotations 2025	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DB-54-GQ68_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221403
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.37844
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-587	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GTPase activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K59239976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11242
RCOR1	ChEA Transcription Factor Targets	1.0	null
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.69594
Prostate adenocarcinoma_PRAD_TCGA-EJ-5506-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63453
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833947
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54962
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.725428
PMC11630641-mmc8.xlsx-Human_1000cell_NOT_identified-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96529
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5377
STAT5A	ENCODE Transcription Factor Targets	1.0	null
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10627
MCF7_PCI-34051_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128913
H3K36me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18817
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6319725-pone.0204197.s006.xlsx-Table_S2-S2_TABLE_-_Operon_Expression_and_SOM_clustering_data_for_Gene_Set_identified_by_ANOVA_p_0_005_1005_genes_FDR_8_8_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
HEC59	CCLE Cell Line Gene Expression Profiles	1.0	1.47787
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.705275
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.88771
hsa-miR-146a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83895653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13337
CP-645525-01-7515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826939
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37659
P-loop containing nucleoside triphosphate hydrolase	InterPro Predicted Protein Domain Annotations	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22791
Bardet-Biedl syndrome 19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91022
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CDK1	Pathway Commons Protein-Protein Interactions	1.0	null
GAMG	DepMap CRISPR Gene Dependency	1.0	3.48089
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40685792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48663
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.968131
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AE-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50163
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00712
BRD-K14416602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00249
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11164
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3908	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52359
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.390094
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05543
TRRAP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05068
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CSNK1A1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DG-75	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.45899
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OC316	DepMap CRISPR Gene Dependency	1.0	4.18804
NCIH2286	DepMap CRISPR Gene Dependency	1.0	3.24594
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNX2	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09615
KE-37 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
thalamic (p2) zona limitans domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35628
BRD-K45969405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91946
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
DEL	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.20094
planum polare, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93426
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929193
hsa-miR-4433	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92643
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3201
BRD-K61691014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68928
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051103
SPECC1L	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23841
scopolamine N-oxide-1415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01969
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MNT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5284
u937	HPA Cell Line Gene Expression Profiles	1.0	1.23295
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52375
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.204
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAD2L1	Pathway Commons Protein-Protein Interactions	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anticancer	GeneRIF Biological Term Annotations	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12545
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826064
Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65538
lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.133957
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29598
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07104
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430319
intracellular protein transport	GO Biological Process Annotations 2025	1.0	null
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24982
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41875112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63494
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346675
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354084
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24982
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01314
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59402582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00212
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98461
BRD-K64859133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30616
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.26205
ATP6V1G1	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MAX_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEC22B	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4306	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K51490423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28198
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26184
VAC14	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4410-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.83227
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8945
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.82637
Ventromedial hypothalamic nucleus, dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0938
dihydroergotamine-2081	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2334
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36464765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50636
GSE57871_1_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2521
CB-32-EI69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37787
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68504
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.20472
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31143
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_10_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_YY1_21170310	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GA10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56277
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08954
GSE169155_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73922
doxorubicin_homo sapiens_gpl550_gds848	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31905
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03139
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10948
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39996
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988335
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853506
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NRBP1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.56095
GSE232472_1_v_2_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
USE1	Pathway Commons Protein-Protein Interactions	1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375167
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.89486
BRD-K30310008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00582
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21401
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31345
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.900917
indapamide-2361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241446
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SEPT9	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65974
BRD-K83135157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32485
hsa-miR-497	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291596
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11595
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VASP	Pathway Commons Protein-Protein Interactions	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79274
CRCGN008_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9182
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050975
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A05456882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17379
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1592
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20612
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3702285-cddis2013211x6.pdf-339-FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
adiphenine-1709	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	2.12643
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03463
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.3751
BHY	CCLE Cell Line Gene Expression Profiles	-1.0	-3.40049
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-424	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
thymus hypoplasia	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K62318087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80935
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EXOC1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934271
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26742
hupt3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102269_3_v_0_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04684
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9872
SW1783	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61957
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAPGEF4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64175
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88849
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
BRD-A05823365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40187
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51015
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992542
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
UHRF1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18089
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.34462
Perturb_15695_OE_PARG_SRP337621	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.85032
CRCGN017_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6448
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_18604_KO_Zfp708_SRP186171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.63843
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46675
CHD4	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30865
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77638937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4962
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53679
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64325
BRD-K15008902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5856
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6932
Lung adenocarcinoma_LUAD_TCGA-55-6970-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3153	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
bergapten	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25801
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158005
hsa-miR-543	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17972
697	Achilles Cell Line Gene Essentiality Profiles	1.0	1.75356
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931991
THAP11	ChEA Transcription Factor Targets	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57299
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.207
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06277
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05268
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_2_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SMAD4	Pathway Commons Protein-Protein Interactions	1.0	null
VAMP7	Pathway Commons Protein-Protein Interactions	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53098
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-549	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08562
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03844
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCILY18	DepMap CRISPR Gene Dependency	1.0	7.84837
BRD-A57353172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01244
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.137
ARL1	Pathway Commons Protein-Protein Interactions	1.0	null
control	GeneRIF Biological Term Annotations	1.0	null
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996524
hsa-miR-555	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VAPB	Pathway Commons Protein-Protein Interactions	1.0	null
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24201
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29412
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89078
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61195
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07428
GTEX-XMK1-0326-SM-4B652	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971363
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06366
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842095
PRAF2	Pathway Commons Protein-Protein Interactions	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70612
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_G007-LK_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175201
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7555_KD_SP1_SRP303813	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0442
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.8826
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bipolar Disorder_Cerebral cortex_GSE12649	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53105
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.838855
SCAMP2	Pathway Commons Protein-Protein Interactions	1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6615
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90984
16484322-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929193
hsa-miR-4760-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.982191
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.897296
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
SKCO1_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.29555
Learning Disorders	CTD Gene-Disease Associations	1.0	1.13552
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960667
Perturb_1424_KD_RUNX3_SRP159180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.97951
LNCAPCLONEFGC	CCLE Cell Line Gene Expression Profiles	1.0	1.66889
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16228
SNUC2A_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.47765
YY1	ChEA Transcription Factor Targets	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.972923
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE124375_13_v_12_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84698
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08863
GLO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04595
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230984
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23573
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983593
PSG9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00657344
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	1.42972
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
haloperidol-1669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84418
PPM1A	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.443115
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Gill raker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.587
hsa-miR-136	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.7175
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07572
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10203
MAPK8IP3	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.87785
decreased lymphocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823912
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32428
USF2	ENCODE Transcription Factor Targets	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHA7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GIGYF2	Pathway Commons Protein-Protein Interactions	1.0	null
GNAS	Pathway Commons Protein-Protein Interactions	1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71615
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04006
gtpase activity	GO Molecular Function Annotations 2015	1.0	null
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bipolar Disorder_Lymphocyte_GSE7036	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.69643
CKAP5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38796
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.94849
Perturb_17186_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.943379
SLC25A33	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0883
hsa-miR-4764-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
16484322-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08397
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36601
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.431542
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.67704
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908029
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5627
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDNL2	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-CL-5917-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNAI1	Pathway Commons Protein-Protein Interactions	1.0	null
T47D_BREAST	CCLE Cell Line Proteomics	1.0	2.62434
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24743
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60169
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DW-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.799315
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64019
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	5.62703
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15159
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03787
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25457
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.883251
ANXA4	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10366
hsa-miR-3170	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic ductal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
ATP6V1D	Pathway Commons Protein-Protein Interactions	1.0	null
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4742856-srep20328-s7.xls-Sheet2-ZF_converted_to_Human_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984629
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 4 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29408
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01766
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99503
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493499
MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBP-SCAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.639
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54221
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.829
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54967
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11669
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K18637162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00804
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054269
PPP1R9B	Pathway Commons Protein-Protein Interactions	1.0	null
SNU1214	CCLE Cell Line Gene Expression Profiles	1.0	1.46912
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4014
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16657
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38818
BRD-K77634326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18044
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14636
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.26733
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15331
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.02192
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE241701_4_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_8_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24258
CTNNB1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6308_KD_PUM1_SRP396076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.34547
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12024
all	GWASdb SNP-Phenotype Associations	1.0	0.029834
PLEK2	Pathway Commons Protein-Protein Interactions	1.0	null
B cell differentiation	GO Biological Process Annotations 2023	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7695
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929193
SNX5	Pathway Commons Protein-Protein Interactions	1.0	null
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82004
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844695
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.90716
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87191742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02125
ethanol_homo sapiens_gpl96_gds2767	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06022
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3074
BRD-K40228218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12929
MOSPD2	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12254
SLC38A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59559
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXO3	ChEA Transcription Factor Targets	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80608
BRD-K60799989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01475
496100408_PCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05803
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BLOC-3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
GSE225218_9_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1271_LUNG	CCLE Cell Line Proteomics	1.0	2.72782
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6963
EIF2B2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hek293	HPA Cell Line Gene Expression Profiles	-1.0	-0.90438
STEAP3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphocyte differentiation	GO Biological Process Annotations 2023	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943032
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K30284601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61804
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963733
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
considered	GeneRIF Biological Term Annotations	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.991258
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35247
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13782363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56583
BRD-K60728944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8094
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.739203
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.978292
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL62	CCLE Cell Line Gene CNV Profiles	1.0	1.34449
PTP4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0085
GBF1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-F_MYOG_bindning_in_upregulated-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K09271653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1008
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.5835
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01235
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.107
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63531
GTEX-T2IS-0226-SM-32QPH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41149
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51839
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06623
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K29660619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48655
ATP6V1B2	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35058
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.993571
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A-19761587-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11212
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926123
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1776
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0916
IGF1R_druginhibition_47_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.27763
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO3-22982991-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5155-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939115
DMS114	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5219
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sulfachlorpyridazine-2191	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ARL6IP1	Pathway Commons Protein-Protein Interactions	1.0	null
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0751
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956782
SEC61B	Pathway Commons Protein-Protein Interactions	1.0	null
A549_BMS-911543_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131051
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.926581
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PDHK4	Kinase Library Serine Threonine Kinome Atlas	1.0	null
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2203
S0-EE-U3YG_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24921
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57952
CDC42	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839845
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03282
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30256
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05372
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
natural killer cell activation	GO Biological Process Annotations 2025	1.0	null
GSE215086_1_v_7_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1573_LUNG	CCLE Cell Line Proteomics	1.0	2.20205
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878472
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02133388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80693
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DGKQ	Pathway Commons Protein-Protein Interactions	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849053
BRD-A34774643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26447
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
celecoxib-377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE171572_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62361
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DB-21-FY75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225659
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Polysomnography	DisGeNET Gene-Phenotype Associations	1.0	null
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15843
A549_Trichostatin A_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.010229
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydrolase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K10288935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16681
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.18259
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93916
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
HUG1N	CCLE Cell Line Gene Expression Profiles	1.0	2.07381
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A77488069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31546
SYNE2	Pathway Commons Protein-Protein Interactions	1.0	null
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31829
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTP binding	GO Molecular Function Annotations 2025	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04619
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.688838
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10174
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-509-3-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0295
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948881
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4795
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27267
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22272
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.48048
mda-mb-231 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692085
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964685
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1338_KD_HMGN3_DRP007117	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.12879
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
bed nucleus of the stria terminalis, mediocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35817
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11158
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6031_KD_LOXL1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74754
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981357
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548ag	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0334
BCCIP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73357
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.883418
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322608
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPNE1	Pathway Commons Protein-Protein Interactions	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
TRIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3473
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
URGCP	Pathway Commons Protein-Protein Interactions	1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2762
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35669
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12906
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.973994
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Osteoarthritis_Chondrocyte_GSE16464	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.37476
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGD4	Pathway Commons Protein-Protein Interactions	1.0	null
TJP1	Pathway Commons Protein-Protein Interactions	1.0	null
isotretinoin-2407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SEPT14	Pathway Commons Protein-Protein Interactions	1.0	null
S0-EE-YNU4_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218018
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44916
HCT15	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
YY1-21170310-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920395
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DST	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52977
Sin3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36968
BRD-K21864149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17374
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95714
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09409
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10982
FOS	JASPAR Predicted Transcription Factor Targets	1.0	null
EXOC2	Pathway Commons Protein-Protein Interactions	1.0	null
ASAH1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4818-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.43157
ATM	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BAZ1A	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57717
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71493061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80263
BRD-A48478073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0822
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_FIGLA-Unnamed_1_FIGLA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K01310096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39628
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08671
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
SAR1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49645
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.05211
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FRMPD3	Pathway Commons Protein-Protein Interactions	1.0	null
JAK1	Pathway Commons Protein-Protein Interactions	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237963
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19M-06A-61R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-1126-SM-3DB7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03867
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833322
Insect tracheal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
RELA_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K73042446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31123
chloropyramine-3011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.66376
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K54111001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25261
CHD7	ENCODE Transcription Factor Targets	1.0	null
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77953
BRD-K28919392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0286
protein homodimerization activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K95334975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19068
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46908
PMC4944136-srep28995-s2.xls-NOBOX-gene_NOBOX	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB435S	CCLE Cell Line Gene CNV Profiles	1.0	1.42566
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2665
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3304
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36636
VPS4A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02991
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340906
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-195	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41103
LRP10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08547
SACM1L	Pathway Commons Protein-Protein Interactions	1.0	null
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02363
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2656-01A-02R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cloperastine-3608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
valproic acid-409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47598
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22975
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8005-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
170MGBA	DepMap CRISPR Gene Dependency	1.0	2.8952
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58545
ChaGo-K-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.11501
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5764
SNPH	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.19379
RTN3	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09657
NRAS	Pathway Commons Protein-Protein Interactions	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4419b	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer CP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904192
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835744
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90381
TIE1_knockdown_107_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.5348
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.20291
FHL2_Deficiency_GDS3344_596_mouse_Spontaneously immortalized embryonic fibroblasts (EFs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878702
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64227
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-2426-SM-3NB2V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13758
GTPase activity	GO Molecular Function Annotations 2025	1.0	null
hsa-miR-4478	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
reticular complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04882
ELF1	ENCODE Transcription Factor Targets	1.0	null
TLN1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K63919349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58395
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.876641
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0459
obesity	GWASdb SNP-Disease Associations	1.0	1.28906
hsa-miR-3591-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
BB-11-JI42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212563
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549	Achilles Cell Line Gene Essentiality Profiles	1.0	1.55706
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00358
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060865
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12877
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3739
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.591216
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80964
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98278
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12308
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25574
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26752
Embryo Loss	CTD Gene-Disease Associations	1.0	1.10175
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92364_1_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_UNC0379_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00956424
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83324
DGKK	Pathway Commons Protein-Protein Interactions	1.0	null
GSU	CCLE Cell Line Gene CNV Profiles	1.0	2.00383
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05081
GOLPH3	Pathway Commons Protein-Protein Interactions	1.0	null
COMMD3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K60166659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01168
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1054
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APP	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ADRM1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K79032360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24273
NCIH226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83463
BRD-K15380626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.45238
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.17163
RAB13	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4423-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
BRD-K43966357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42345
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5281
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53962
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3184
VPS33B	Pathway Commons Protein-Protein Interactions	1.0	null
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05408
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53639581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36749
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.89733
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240626
CHMP1B	Pathway Commons Protein-Protein Interactions	1.0	null
increased body weight	GWASdb SNP-Phenotype Associations	1.0	1.12851
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48052543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95652
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97562463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08303
CRCGN015_HEPG2_48H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.55822
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.013
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNPY3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10399
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.46556
NCIH1993	DepMap CRISPR Gene Dependency	1.0	11.3162
dyclonine-7022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STX17	Pathway Commons Protein-Protein Interactions	1.0	null
JURKAT	BioGPS Cell Line Gene Expression Profiles	1.0	0.892159
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.325675
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A8JM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11971
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AR	ChEA Transcription Factor Targets	1.0	null
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58631
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08457
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.634047
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34853
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37218
BRD-K93698227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.179
TOMM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40986
RAB10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27948
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4975902-12864_2016_2842_MOESM12_ESM.xlsx-targets_of_IRF8_in_NSCLC-COX7C_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76775
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12315
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO783	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.21428
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83986
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17024
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12408
icSARA deltaORF6_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.26164
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83451
PMC6606599-41598_2019_45777_MOESM14_ESM.xlsx-SAVA_DE_genes_promoter_DMRs-Unnamed_22_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN011_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25305
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.973168
hsa-miR-4426	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Lung adenocarcinoma_LUAD_TCGA-35-3615-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67563379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54766
MYCN	ChEA Transcription Factor Targets	1.0	null
BRD-K66432757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10449
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42566
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4953
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.40924
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
BRD-K73376409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62568
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42896
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64402
BRD-K54627309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7528
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59724
LAMP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06437
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.926011
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27043
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
natural killer cell differentiation	GO Biological Process Annotations 2023	1.0	null
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08594
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130014
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92739
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.35197
hsa-miR-450b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70594
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system mesenchymal non-meningothelial tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOCK1	Pathway Commons Protein-Protein Interactions	1.0	null
pyrophosphatase activity	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0892
HCFC1	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EW1	DepMap CRISPR Gene Dependency	1.0	2.24785
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34388
ATN-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.31792
DKMG	DepMap CRISPR Gene Dependency	1.0	2.90788
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73251
Lip And Oral Cavity Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
BRD-K74537058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19639
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.08247
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4077-01B-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ECSIT	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36865
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38391
ACAP2	Pathway Commons Protein-Protein Interactions	1.0	null
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82021
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07983
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935454
KLC4	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2045
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1626-SM-3K2AJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00271
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29505
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STX12	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906912
22RV1	DepMap CRISPR Gene Dependency	1.0	2.07936
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92286
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999308
Lung adenocarcinoma_LUAD_TCGA-44-2655-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869721
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
znf148_21828133_erythroblast_lof_human_gpl571_gse31092	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.10967
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03818
PMC10624900-41467_2023_42825_MOESM13_ESM.xlsx-Module_3-ZNF195_ZNF195	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88147
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43208
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26436
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43948
hsa-miR-4457	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
abnormal T cell number	MGI Mouse Phenotype Associations 2023	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23841
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1126
establishment of localization	GO Biological Process Annotations 2015	1.0	null
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
MAPRE1	Pathway Commons Protein-Protein Interactions	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849769
CHMP5	Pathway Commons Protein-Protein Interactions	1.0	null
KNS81	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0751
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04397
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22543
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KYSE70	CCLE Cell Line Gene Expression Profiles	1.0	1.34913
TRIM24	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11909
BRD-K87926172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55174
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04525
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15045
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830187
BRD-K83892314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27747
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
organic substance transport	GO Biological Process Annotations 2015	1.0	null
EIF2D	Pathway Commons Protein-Protein Interactions	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04108
hsa-miR-4769-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
EST1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A99402294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03599
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35733
ELF1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_SRT1720 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133844
LMO7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	2.08616
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5217
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.65288
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941228
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852837
ARAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE182680,GSE182683_7_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.502
PLA2G4B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.579
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.902583
Perturb_10197_KD_FIP1L1_SRP251753	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843333
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12468
SUDHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.57947
Bardet-Biedl syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
guanyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.057
BRD-K50623282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56908
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16023
BRD-K86912219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83505
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36024
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0359
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6473-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15673
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9661
BRD-K14262397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52153
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228536
embryonic lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
YY1-21170310-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04751
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92036
NZM7	DepMap CRISPR Gene Dependency	1.0	3.691
E2F6	ENCODE Transcription Factor Targets	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28247
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RI-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0699
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76549
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84783
Perturb_5255_KO_Morc3_SRP318570	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.05777
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2023	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15516
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73734
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268479
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896654
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548ai	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
ARL8A	Pathway Commons Protein-Protein Interactions	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.28566
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16968
RAB17	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11783
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846068
1742_COG3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.540462
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868812
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15539
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4913
SC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.59417
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14336
CDK5	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875579
CHD1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCARB2	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08647
Rheaume et al.Nat Commun.35_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992878
BIN1	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928464
HTT	Pathway Commons Protein-Protein Interactions	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.845176
BRD-K56592061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29322
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34098
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89017
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9077
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34098
HUNK_knockout_240_GSE14226	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.83063
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13676
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.44443
OSBPL10	Pathway Commons Protein-Protein Interactions	1.0	null
SNX3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-1284	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PLEKHA5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.26387
ANKRD11	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63609
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	1.54807
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HUPT4	DepMap CRISPR Gene Dependency	1.0	2.28158
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56713
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAM10	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094373
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLS1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02885
intracellular protein transport	GO Biological Process Annotations 2015	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058498
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44372
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061176
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
GOPC	Pathway Commons Protein-Protein Interactions	1.0	null
EIF2B3	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KALS-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.40426
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ANXA3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04831
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22913
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-7332-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.57666
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59842
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88163
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.38353
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-A69648159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18029
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33400588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18839
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849086
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336872
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Ensemble_gene_ID_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
CC-49-CQ25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241201
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5626
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28927
BRD-K72997741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01758
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.03774
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62472
TPX2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855856
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29045
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.12141
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.835875
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52115
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49762
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217423
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GSE148066,GSE157787_2_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24272
GTP binding	GO Molecular Function Annotations 2023	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056503
GSE114883_1_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1486
PITPNB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
metergoline-1606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44931
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864386
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2441
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58945
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846992
MAPK7	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1937	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.73918
VTA1	Pathway Commons Protein-Protein Interactions	1.0	null
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
AP3D1	Pathway Commons Protein-Protein Interactions	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.504942
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851841
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1105
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980682
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1	JASPAR Predicted Transcription Factor Targets	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28634
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213033
CHMP1A	Pathway Commons Protein-Protein Interactions	1.0	null
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HC-01-FD24_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319931
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNA11	Pathway Commons Protein-Protein Interactions	1.0	null
PIK3C2B	Pathway Commons Protein-Protein Interactions	1.0	null
DOCK5	Pathway Commons Protein-Protein Interactions	1.0	null
SYK	Pathway Commons Protein-Protein Interactions	1.0	null
Rab-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.314
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77909
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64698855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03495
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1792_LUNG	CCLE Cell Line Proteomics	1.0	4.11064
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.239
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19949
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58148
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15507
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6156
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0226
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21987
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4794	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4818
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81924
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	0.994424
BRD-K19040732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35717
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25U-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1251	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SEL1L	Pathway Commons Protein-Protein Interactions	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64698045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39387
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52227
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15976
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
RAB19	Pathway Commons Protein-Protein Interactions	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
CCK81	CCLE Cell Line Gene Expression Profiles	1.0	1.99832
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894244
SNX14	Pathway Commons Protein-Protein Interactions	1.0	null
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966802
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE57871_1_v_10_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
valproic acid-410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Waisman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
EXOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0043
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.16077
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44247
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH2171	Achilles Cell Line Gene Essentiality Profiles	1.0	1.53507
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.56407
SRF	ENCODE Transcription Factor Targets	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.228205
EBC-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-7.15481
BRD-K79887921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57097
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01375
BRD-K37402529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04635
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18422
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0062
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19077
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.375368
PMC12486367-Supplementary_Data2.pdf-390-ZNF512_ZNF512	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42322
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22975
hsa-miR-4694-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A6UM-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
glis3_19805515_embryonic_pancreas_lof_mouse_gpl1261_gds3812	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.5316
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K70876639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14366
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
intercalate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47598
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07324
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896686
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
trichostatin A-1306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.487213
STAT3	Pathway Commons Protein-Protein Interactions	1.0	null
endomembrane system	GO Cellular Component Annotations 2015	1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48305
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830039
OC-71-BZ81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204561
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
CDK4	Pathway Commons Protein-Protein Interactions	1.0	null
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37244
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12215
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.44703
CRCGN015_MCF10A.TP53.M_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.138
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23744
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.87137
A549_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0229866
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.925814
SP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57773
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11051
DOCK6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07141
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91841
RAP1GDS1	Pathway Commons Protein-Protein Interactions	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02199688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57888
AE-18-ZM98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228934
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0287
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03526
terconazole-2844	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RASL11A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K12640996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13515
HLA-C	Pathway Commons Protein-Protein Interactions	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.339
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6940-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914094
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.20518
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GSE201309_5_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
XPO4	Pathway Commons Protein-Protein Interactions	1.0	null
USP8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	7.21341
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-15b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TU-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
localization	GO Biological Process Annotations 2015	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92817
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78397
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94642
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K32403186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62343
CA-48-CT20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226377
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11248
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92817
COPG1	Pathway Commons Protein-Protein Interactions	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00025
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.74717
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20557
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0922
decreased birth body size	MGI Mouse Phenotype Associations 2023	1.0	null
STAMBPL1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K39176069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46093
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.1585
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17937
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2956
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44398
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57984
BRD-K82362034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69172
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00186
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1_KO_GSE40296_7_mouse_brain (telencephalon)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
1971_CWC15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507326
SNRNP27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07723
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920395
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.40591
periventricular stratum of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35817
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	2.62145
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3891
reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05776
BRD-A66369147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03383
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82225
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835105
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Keratocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
colonrectum_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.847311
BRD-K77663497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.661
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.70597
esr1_21299862_mcf7_lof_human_gpl570_gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.044609
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60013
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76046
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838249
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46621
RABAC1	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of Ras protein signal transduction	GO Biological Process Annotations 2023	1.0	null
OC-10-FB51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205626
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
valproic acid-1665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB11B	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38388
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14641
VIPAS39	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22975
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07019
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70128
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32838
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839294
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18627
midodrine-1403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Zona incerta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39123
ascorbic acid-1610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-NFE2L2_V2-Gene_name_NFE2L2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K48749255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10928
THP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.26011
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-1.827
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01389
BICR31	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.80001
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55968
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17987
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49171
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
A549_Gandotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149762
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF4A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73605
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871717
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE215155_0_v_1_golph3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1	ChEA Transcription Factor Targets	1.0	null
ARF4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2798
496100287_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43127
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(ZEBOV)_6hr_Macrophage_22028943_GSE31747	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.85492
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5304-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC50	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23603
hsa-miR-616	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.66414
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-97-KP88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20912
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11216
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841011
BRD-K85546819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01276
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein localization	GO Biological Process Annotations 2023	1.0	null
wortmannin-1668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947862
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27558
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77827548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64025
wi26va4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.845
intermediate stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45562
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4654	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06245
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8782
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BL2290 (BTBD12)	NURSA Protein Complexes	1.0	null