association	dataset	threshold value	standardized value
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.845805
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941894
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
CTB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE238018_1_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_2_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
GSE233112_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067414
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
Alveolar cell type II	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911973
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354084
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.048
PMC3470785-NIHMS377161-supplement-3.pdf-233-E4F1_E4F1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of T cell mediated cytotoxicity	GO Biological Process Annotations 2025	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2815-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2710-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.532899
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056101
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5127
HE-22-JR80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206281
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.4095
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8944
PMC5543083-41467_2017_268_MOESM5_ESM.xlsx-Topological_properties_of_nodes-Supplementary_Data_4_Topological_properties_of_the_nodes_present_in_E2F1_interaction_map_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133329_1_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6626
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.971334
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192362_1_v_0_erastin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.66353
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29244
Car cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0939
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92649
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune	GeneRIF Biological Term Annotations	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.208
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.664425
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03842
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11528209-cd-23-1212_supplementary_table_s7_suppst7.xlsx-H358_EML4_KD_DEGs-List_of_DEGs_of_EML4-knockdown_vs_control_H358_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7656
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Multiple myeloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
among	GeneRIF Biological Term Annotations	1.0	null
LPS27	DepMap CRISPR Gene Dependency	1.0	9.19288
PMC5543083-41467_2017_268_MOESM5_ESM.xlsx-Interactions_in_E2F1_map-Supplementary_Data_4_Interactions_between_nodes_in_E2F1_map_Cytoscape_version_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72194
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643263
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838989
POLR2A	ENCODE Transcription Factor Targets	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE111247_14_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2638
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997362
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871401
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.1548
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
natural killer cell lectin-like receptor binding	GO Molecular Function Annotations 2015	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5903-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alopecia Areata	CTD Gene-Disease Associations	1.0	2.88009
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25342
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
MNT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.694261
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37954
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8464
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28345
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alopecia	DisGeNET Gene-Disease Associations	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09453
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.715258
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	2.15793
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5701
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.733015
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.58
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243226
Hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
Lymphoma, Non-Hodgkin	HuGE Navigator Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836666
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7834-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.9379
strength	GeneRIF Biological Term Annotations	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
JUND_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53166
MJ	DepMap CRISPR Gene Dependency	1.0	4.26149
SF126	DepMap CRISPR Gene Dependency	1.0	2.04223
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60284
genetic	GeneRIF Biological Term Annotations	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LS123	CCLE Cell Line Gene CNV Profiles	1.0	1.70148
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239913
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
PMC7217064-IJC-146-3354-s004.xlsx-Table_S5-Supplementary_Table_S5_Genes_significantly_upregulated_in_OC2-transfected_AGS_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058241
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.0206
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05771
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.868638
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44471
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trophoblast giant cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040238
MAX	ENCODE Transcription Factor Targets	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-01A-31R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34902
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044911
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365124
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RO-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47056
BFTC909	DepMap CRISPR Gene Dependency	1.0	2.76154
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	0.980538
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.94856
NCIH1395	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07348
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040728
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Myeloid neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.474258
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076087
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	GO Biological Process Annotations 2025	1.0	null
PMC11378415-12943_2024_2100_MOESM6_ESM.xlsx-CopyNumberGain_ExpDown-GRHL1_GRHL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	5.41727
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91207
innate immune response	GO Biological Process Annotations 2015	1.0	null
Bone marrow cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.22
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GSE213228_1_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DR-A0ZL-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91276
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91207
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62521
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hematologic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1435
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0353
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus	GTEx Tissue Gene Expression Profiles	1.0	1.38119
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KM12	DepMap CRISPR Gene Dependency	1.0	3.68053
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
null cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.774004
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054205
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hair follicle epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QD-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D341Med	DepMap CRISPR Gene Dependency	1.0	2.52909
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17404
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073843
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48078
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
interleukin-15 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.06015
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Diffuse alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.41584
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GR-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bone marrow disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
GSE227592_13_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05379
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03492
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-0.982182
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.869306
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83284
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.425769
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.29494
hypersensitivity reaction type ii disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20551
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.35781
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
GATA3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21669
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.27635
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50118
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33054
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15417
ZNF217	ENCODE Transcription Factor Targets	1.0	null
hematologic	GeneRIF Biological Term Annotations	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
Kidney renal papillary cell carcinoma_KIRP_TCGA-O9-A75Z-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.965006
A4-FUK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A5NC-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
chr6_150021260_G_C_b38	GTEx eQTL 2025	1.0	1.04397
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5502
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
IKZF1	ChEA Transcription Factor Targets	1.0	null
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6229-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081858
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30187
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892852
aortic root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.794375
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.17319
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
anchored component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
polymorphic	GeneRIF Biological Term Annotations	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
non-Hodgkin lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.989018
SNU119	CCLE Cell Line Gene CNV Profiles	-1.0	-2.25983
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50118
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-182	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.6155
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNAS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47482
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039532
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.12922
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.22298
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31867
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09361
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066115
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21802
Lung squamous cell carcinoma_LUSC_TCGA-66-2759-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83927
amide binding	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H292 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5964
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.982182
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.44743
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
efo21	HPA Cell Line Gene Expression Profiles	1.0	0.926479
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53355
NUPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52993
SH4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6117
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A897-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.108
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of T cell mediated immunity	GO Biological Process Annotations 2025	1.0	null
alopecia	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
JUND_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2844
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4231
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90758
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56738
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	2.2136
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9225
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Natural killer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.668
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37435
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898271
Lung squamous cell carcinoma_LUSC_TCGA-85-8276-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23843
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.0319
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965259
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.94952
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
influence	GeneRIF Biological Term Annotations	1.0	null
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-79-5596-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	3.79602
SNU61	CCLE Cell Line Gene CNV Profiles	1.0	1.36497
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836211
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840122
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9436
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03842
groups	GeneRIF Biological Term Annotations	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051608
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.32359
H4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
peptide antigen binding	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4583-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22961
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754339
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.389
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65502
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05323
Intraocular melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
CB-87-RB49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225186
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alopecia areata	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.468194
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893308
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alopecia areata	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.83979
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20551
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.0647
FOS	ENCODE Transcription Factor Targets	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.825557
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.16371
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838388
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.58
Connective tissue disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10273062-JCMM-27-1708-s001.xlsx-Sheet_1-CESC_AND_UCEC_NOT_BRCA_NOT_UCS_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53355
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347778
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50118
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8505-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14499
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194287
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15417
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943553
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Autoimmune Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
tonsil_8a1	HPA Tissue Sample Gene Expression Profiles	1.0	1.16807
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90259
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062521
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.466016
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21669
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055858
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5066615-supp_30.18.2093_Supplemental_Table_S1.xlsx-GR_YBX1_and_HRSP1_down_1_5_fold-Unnamed_1_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15417
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
here	GeneRIF Biological Term Annotations	1.0	null
Inflamed seborrheic keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
UT7	CCLE Cell Line Gene CNV Profiles	1.0	1.76299
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5529
Immunological synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.172
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
IKZF1-21737484-HCT116-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0571
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7430-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.48388
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7243
Pulmonary emphysema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.93437
Cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.996334
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213650_0_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059437
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	GO Biological Process Annotations 2025	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163317
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
EP300	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4329
antigen processing and presentation	GO Biological Process Annotations 2015	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
SUDHL8	CCLE Cell Line Gene CNV Profiles	1.0	2.20337
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.54535
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85863
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472704
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42495
PMC10158025-ijbsv19p2081s6.xlsx-SupTable5-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
MHC protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
interleukin-28 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4538-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.274516
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23951
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11699013-12672_2024_1699_MOESM1_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_The_association_between_proteins_and_CLL_in_the_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
FU97	DepMap CRISPR Gene Dependency	1.0	2.20539
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87525
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Myelodysplastic Syndromes	HuGE Navigator Gene-Phenotype Associations	1.0	null
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	1.3366
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.431843
EM2	CCLE Cell Line Gene CNV Profiles	1.0	2.40054
Lung squamous cell carcinoma_LUSC_TCGA-94-A5I4-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-7030-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01308
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76714
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.521441
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.39117
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06655
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054668
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15417
Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836666
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965761
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9744
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CH-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE148269,GSE148273_0_v_1_arid4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7652-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7015
Kidney renal papillary cell carcinoma_KIRP_TCGA-AT-A5NU-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4166
GSE185744,GSE185747_0_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4II-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alloreactive	GeneRIF Biological Term Annotations	1.0	null
BATF	ENCODE Transcription Factor Targets	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
receptor binding	GO Molecular Function Annotations 2015	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13876
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.14288
MHC class I protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.528
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE246660_1_v_0_lmo3_human	RummaGEO Gene Perturbation Signatures	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892852
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.27917
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.67149
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.948822
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2927
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair follicle dermal papilla cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
Colo-201 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7576141-41598_2020_74792_MOESM7_ESM.xlsx-CBX2-Unnamed_5_CBX2	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19426
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7319
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.384665
E2F4	ENCODE Transcription Factor Targets	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.982182
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954628
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76714
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCK81	CCLE Cell Line Gene CNV Profiles	1.0	1.6199
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.54424
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.14866
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.206082
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.899059
large granular lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.790212
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.78263
GSE111247_14_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.30187
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.61064
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
antigen processing and presentation of peptide antigen	GO Biological Process Annotations 2015	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985462
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06651
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.3807
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21903
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2517
BA/F3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06057
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.556375
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38206
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.59713
SNUC4	DepMap CRISPR Gene Dependency	1.0	2.60844
PMC6172843-13059_2018_1523_MOESM6_ESM.xls-Sheet1-Table_S5_mRNAs_variation_abundance_1_5-fold_in_YBX1-knockdown_BGC-823_cells_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15842
Natural killer cell mediated cytotoxicity	KEGG Pathways 2026	1.0	null
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00466
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185744,GSE185747_0_v_1_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
C99	DepMap CRISPR Gene Dependency	1.0	2.51368
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67743
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5504
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111309
PMC4123077-cddis2014283x10.xls-Sheet1-Table_S5_Genes_upregulated_by_HAND1_in_DLD1_cells_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917344
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5232-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_right-y_TFEB_KO_LLOMe_VS_WTLLOMe_UP_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
polymorphism	GeneRIF Biological Term Annotations	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21105
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.31254
graft-versus-host disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938913
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	2.22462
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
External side of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648938
PMC4721115-13148_2016_171_MOESM1_ESM.xlsx-SOM_Table_10-Gene_Symbol_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29437
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22961
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
Prostate adenocarcinoma_PRAD_TCGA-HC-7233-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Ribonuclease H2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4V9-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.544048
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.384665
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840122
Alopecia Areata	HuGE Navigator Gene-Phenotype Associations	1.0	null
Gamma delta T-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.986
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TYKNU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73379
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3012
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210179
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE185865_0_v_1_celf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64148
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
Integumentary system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
natural killer cell mediated cytotoxicity	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-26-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	2.3732
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269186
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC71	CCLE Cell Line Gene CNV Profiles	1.0	1.484
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_GSC-Unnamed_3_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
sixth	GeneRIF Biological Term Annotations	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943553
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	3.70424
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.40288
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metabolism of proteins	Reactome Pathways 2024	1.0	null
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7458
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
immune effector process	GO Biological Process Annotations 2015	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91207
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054388
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59452
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29137
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273541
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukocyte mediated cytotoxicity	GO Biological Process Annotations 2015	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.71142
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273935
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209476
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51272
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73Q-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to stress	GO Biological Process Annotations 2015	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65502
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
KYO1	CCLE Cell Line Gene CNV Profiles	1.0	1.72952
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067414
MET_knockdown_254_GSE38343	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.57245
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287113
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.112651
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28526
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34902
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043757
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
antigen processing and presentation of endogenous peptide antigen via MHC class Ib	GO Biological Process Annotations 2025	1.0	null
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.45902
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pleural cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03285
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.679
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917344
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7885-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27172
HHUA	DepMap CRISPR Gene Dependency	1.0	4.00254
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227698_5_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HT	DepMap CRISPR Gene Dependency	1.0	4.08494
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65502
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dermal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8214
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.441
RL952	DepMap CRISPR Gene Dependency	1.0	2.1535
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.606981
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CR-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4905481-oncotarget-07-11397-s003.xlsx-Pinin_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406548
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
locus	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254136
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
hacat	HPA Cell Line Gene Expression Profiles	1.0	1.68607
T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.504
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
immune response	GO Biological Process Annotations 2015	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAMP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.032
antigen processing and presentation of endogenous peptide antigen	GO Biological Process Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69208
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Autoimmune disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
MHC class I alpha chain, alpha1 alpha2 domains	InterPro Predicted Protein Domain Annotations	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
AA-58-JC44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214996
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93458
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.459
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.62739
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55048
Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30253
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DJ-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438739
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.835
ERG_01_216	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63814
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.452081
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.27064
MDA-MB-468	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
Cowpox	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
MYC	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03013
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6021-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.01047
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984288
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03314
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373159
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97P-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49673
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EM-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.547326
PMC5543083-41467_2017_268_MOESM5_ESM.xlsx-Interactions_in_E2F1_map-Unnamed_2_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Alopecia universalis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UE-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37643
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.52533
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.76714
CTV1DM	DepMap CRISPR Gene Dependency	1.0	6.44561
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054288
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05623
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.43566
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.53458
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
Prostate adenocarcinoma_PRAD_TCGA-CH-5791-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNGM	DepMap CRISPR Gene Dependency	1.0	2.9044
Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
SNU5	DepMap CRISPR Gene Dependency	1.0	2.29845
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.800751
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0476
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	1.0	1.21961
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5235
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01826
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056666
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126059
natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.794792
biological_process	GO Biological Process Annotations 2015	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.815
CD-35-BD44_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265435
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.73325
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OCILY19	CCLE Cell Line Gene CNV Profiles	1.0	1.43877
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A3LQ-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gamma-delta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SJRH30	CCLE Cell Line Gene CNV Profiles	1.0	1.3714
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72444
NK-92 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Post-translational modification: synthesis of GPI-anchored proteins	Reactome Pathways 2024	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917344
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19903
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91207
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.66753
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56849
PMC11604901-13555_2024_1298_MOESM1_ESM.pdf-97-MT-RNR1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.601049
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8355-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RL952	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69012
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312673
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05323
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0076
SNU1	DepMap CRISPR Gene Dependency	1.0	2.95035
regulating	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988626
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.17952
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
antigen binding	GO Molecular Function Annotations 2015	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32132
GSE226584,GSE226589_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068904
GP5D	DepMap CRISPR Gene Dependency	1.0	10.2905
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.331194
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965259
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary immunodeficiency disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-ND-A4WC-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057039
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Natural killer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.221
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8752
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.85737
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20253
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6802116-41467_2019_12517_MOESM5_ESM.xlsx-Sheet1-D9_8_GNF2-SERPINB5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
RF-04-GI28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283044
SNU5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49383
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tn368	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08332
allogeneic	GeneRIF Biological Term Annotations	1.0	null
CB-44-RT90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.287259
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34568
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
20460173-ImmPortAntigenProcessingandPresentation	GeneSigDB Published Gene Signatures	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.742
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836666
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.944341
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97668
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50I-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.53427
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.480091
JUN_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
FOSL2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STING complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.572
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226115,GSE226116_1_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.836307
ethnic	GeneRIF Biological Term Annotations	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
lymphocyte mediated immunity	GO Biological Process Annotations 2015	1.0	null
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237935
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PK-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72194
Cytolytic granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
LN18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60726
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.67246
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transplantation	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
TBP	ENCODE Transcription Factor Targets	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0939
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.303316
skin	HPA Tissue Gene Expression Profiles	1.0	0.991684
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.459
cell killing	GO Biological Process Annotations 2015	1.0	null
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.245
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9255
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.46317
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316132
GSE235066_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.22669
SW48	DepMap CRISPR Gene Dependency	1.0	4.18583
Lung squamous cell carcinoma_LUSC_TCGA-56-5898-01A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REH	DepMap CRISPR Gene Dependency	1.0	4.06323
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05496
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.235612
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.44094
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.459
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.00852
FOSL2	ENCODE Transcription Factor Targets	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
RHJT	DepMap CRISPR Gene Dependency	1.0	2.08933
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914428
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MOLM-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HG-A2PA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GRHL3_01_336	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61373
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93538
Autoimmune disease of musculoskeletal system	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
TANOUE	DepMap CRISPR Gene Dependency	1.0	2.2811
KDM4A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.51758
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054667
MHC classes I/II-like antigen recognition protein	InterPro Predicted Protein Domain Annotations	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU182	CCLE Cell Line Gene CNV Profiles	1.0	1.41882
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.362322
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.014
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54662
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10333
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
culture supernatant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2779
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
transcript	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43271
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAOV4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37555
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.57811
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.272839
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30635
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.9013
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8ZZ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7726-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22031
Alopecia areata	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.902
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281088
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33948
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.114
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4519
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
hair disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.00335
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.1012
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2ES-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
COV504	CCLE Cell Line Gene CNV Profiles	1.0	2.05922
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41192
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19755
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5769-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99836
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048078
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
normal variation	GAD Gene-Disease Associations	1.0	null
peptide binding	GO Molecular Function Annotations 2015	1.0	null
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324306
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836666
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42958
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53744
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.84256
T3M3	DepMap CRISPR Gene Dependency	1.0	3.17929
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_01_104	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.36415
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34902
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.04446
EP300_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HUT78	CCLE Cell Line Gene CNV Profiles	1.0	1.57896
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
e1a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Leukemia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alpha-beta T cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
STAT3	ENCODE Transcription Factor Targets	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20185
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893308
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.132564
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.526
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
Mesothelioma_MESO_TCGA-LK-A4O5-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
NCIH23	CCLE Cell Line Gene CNV Profiles	1.0	2.43717
HDAC1	ENCODE Transcription Factor Targets	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4385
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	1.0	1.46937
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15521
KOPN-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.524594
DAOY	CCLE Cell Line Gene CNV Profiles	1.0	1.60352
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72537
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051136
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47476
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54519
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893308
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6231
F36P	CCLE Cell Line Gene CNV Profiles	1.0	1.83597
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28043
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.459
Side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65502
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4734-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP3K7_knockdown_37_GDS5023	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.934111
Lung squamous cell carcinoma_LUSC_TCGA-56-8308-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.43066
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051275
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.823981
PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.93821
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01274
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WM115	DepMap CRISPR Gene Dependency	1.0	8.09717
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ink	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26479
treated	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypersensitivity reaction disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.96481
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anchored component of membrane	GO Cellular Component Annotations 2015	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327113
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
small intestine	HPA Tissue Gene Expression Profiles	-1.0	-0.982182
GSE182179_0_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.459
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
Lung squamous cell carcinoma_LUSC_TCGA-68-7755-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060785
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
GSU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32688
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Aortic Root Dilatation	DisGeNET Gene-Disease Associations	1.0	null
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19061
positive regulation of leukocyte mediated cytotoxicity	GO Biological Process Annotations 2025	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YAMATO	DepMap CRISPR Gene Dependency	1.0	2.30602
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of T cell mediated cytotoxicity	GO Biological Process Annotations 2025	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
stem	GeneRIF Biological Term Annotations	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	159.532
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054419
pre-B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
Alopecia areata	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9564
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hypotrichosis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Langerhans cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
MPP-89	COSMIC Cell Line Gene Mutation Profiles	1.0	null
alopecia areata	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
antigen processing and presentation of peptide antigen via mhc class i	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10534
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Post-translational protein modification	Reactome Pathways 2024	1.0	null
defense response	GO Biological Process Annotations 2015	1.0	null
natural killer cell mediated immunity	GO Biological Process Annotations 2015	1.0	null
pc3	HPA Cell Line Gene Expression Profiles	1.0	0.894522
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1734	CCLE Cell Line Gene CNV Profiles	1.0	1.4371
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32548
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.6272
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2073
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	2.18674
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6218-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSN1	DepMap CRISPR Gene Dependency	1.0	5.71943
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.1749
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851528
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WJ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7576141-41598_2020_74792_MOESM9_ESM.xlsx-CBX2-Unnamed_5_CBX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4735693-ncomms10380-s2.xlsx-Sheet1-Supplementary_Data_1_BESC_and_GSC_gene_signature_131_genes_2_5_fold_and_p_0_001_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05711
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29679
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.16
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE185744,GSE185747_0_v_4_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukocyte mediated immunity	GO Biological Process Annotations 2015	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055373
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.41368
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4195
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-U87MG_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7023-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7071-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
expresses	GeneRIF Biological Term Annotations	1.0	null
antigen processing and presentation of peptide antigen via MHC class Ib	GO Biological Process Annotations 2025	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.307521
normalvariation	GAD High Level Gene-Disease Associations	1.0	0.293278
A2780	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70226
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BE-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF7_01_282	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.70711
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893308
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
immune system process	GO Biological Process Annotations 2015	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057823
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Brain Lower Grade Glioma_LGG_TCGA-HT-7483-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.19829
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13876
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5557-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52105
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.115771
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6813
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.02515
LAMA84	CCLE Cell Line Gene CNV Profiles	1.0	1.47436
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.278
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6645
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-5155-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RB1_KD_GSE50532_660_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-1622-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83927
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MHC class I-like antigen recognition	InterPro Predicted Protein Domain Annotations	1.0	null
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.406839
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.37597
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.327956
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT1	DepMap CRISPR Gene Dependency	1.0	6.42973
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057983
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91751
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null