association	dataset	threshold value	standardized value
dilazep-4688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3321
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K39108047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02179
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thiamazole-2570	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09032
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48661
LY-294002-1065	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K26423054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41073
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.57985
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07851
GSE221633_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22176
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus-6927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
glibenclamide-7202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K38557728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19972
etiocholanolone-2204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.826
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972207
MY-M12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.20803
H2BK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15178
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02211
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06466
monorden-999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
caffeic acid-3053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EIF2A	Pathway Commons Protein-Protein Interactions	1.0	null
galantamine-4186	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARP12	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K11054415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25394
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32122
BRD-K96057608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01568
NCF4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K41946683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18694
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26712
hsa-miR-670	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.995025
physostigmine-2768	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04064
ETS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00372974
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01168
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83016
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14349
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44866331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49145
E2F4	ENCODE Transcription Factor Targets	1.0	null
r5 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43279
SNU899	CCLE Cell Line Gene Expression Profiles	1.0	1.69993
GTEX-OOBJ-3026-SM-3NB1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03985
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4636
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94537
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MFH-ino	GDSC Cell Line Gene Expression Profiles	-1.0	-2.27093
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7512
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.47455
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37094
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2686
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.14324
BRD-K52876244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41806
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951857
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897408
BRD-K86903429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11153
0175029-0000-4716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K97332312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74901
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.00215
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4989
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39581
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33336
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTG2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
zomepirac-6815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4318
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11244912-media-3.xlsx-Sheet2-ESR1_mutation_E2_Co-UP_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73549
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21128
BRD-K36252987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27818
MORCPR	DepMap CRISPR Gene Dependency	1.0	4.78774
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16849
bicuculline-4574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178714_1_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867025
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.13518
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5013636-ncomms12601-s5.xlsx-FREAC2-Groups_FOXF2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
mouth	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EW-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13767
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Perturb_5611_OE_Tpm4_SRP346384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08603
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14733
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54785440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4139
BEN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45235
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_1_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE110300,GSE110304_0_v_1_estradiol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21408
BRD-K37315860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42565
BRD-K72647169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96767
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904265
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45028
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.11626
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0219
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
GTEX-WFJO-1126-SM-4LVLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875848
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCCSUP	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01068
MCF7_Cerdulatinib_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00996057
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09204
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.5524
mifepristone-7183	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
terazosin-2530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dydrogesterone-2156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0087
BRD-K69437108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30404
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
STOCK1N-35215-6422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23208
GSE108675_2_v_1_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36376
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.06225
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.3215
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13857
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946018
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.8259
Lung squamous cell carcinoma_LUSC_TCGA-85-8580-01A-31R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07708
ACTG1	Pathway Commons Protein-Protein Interactions	1.0	null
lynestrenol-6756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cefuroxime-2526	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q734-0826-SM-48U1G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06656
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.30879
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09073
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3876
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	1.39616
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SW48	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.31693
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39581
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.50765
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20327
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.6247
BRD-K54660148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16715
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921157
CFPAC1	CCLE Cell Line Gene CNV Profiles	1.0	1.34303
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06357
BRD-K16062794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35169
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VAL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41593
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41179
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77679
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4270	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
abnormal response to infection	MPO Gene-Phenotype Associations	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12601
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869944
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8339
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45981
MCF7_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169075
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32596
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.825893
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.608
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-29c	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ZIC3_ZIC3	Rummagene Transcription Factor Associations 2026	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050827
BRD-K30964167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55816
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04848570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4958
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21473
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.06143
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.63462
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33841
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.377
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.058
propoxycaine-6161	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
oxetacaine-4246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45245001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45177
ciclosporin-261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1785
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05901
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22664
BRD-K34311186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21877
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15128331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1743
CRCGN017_MCF10A.WT.HP_24H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4243
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPMI 2650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51082
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00288
JUND	ENCODE Transcription Factor Targets	1.0	null
positive regulation of gtpase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-OXRK-0526-SM-3NB2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16527
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1204
BRD-K41887762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30246
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	1.15546
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63435
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85085
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922709
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
rolitetracycline-3031	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPS5	Pathway Commons Protein-Protein Interactions	1.0	null
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20372
DGKQ	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619888
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38733341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18642
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.42368
RBPJ	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A5DS-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
flufenamic acid-5478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72318
White blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4301
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7513
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
BRD-K59155687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39815
isopropamide iodide-2720	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
chlortetracycline-6761	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1194
MDA-MB-453	GDSC Cell Line Gene Expression Profiles	-1.0	-2.42407
RT11284	DepMap CRISPR Gene Dependency	1.0	2.97053
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MAFA_MAFA	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858702
BRD-K33787033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21742
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40849
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06862
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
genistein-1660	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23844489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02455
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.06307
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06698399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31951
estradiol-414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF189	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1479
EGR1	ENCODE Transcription Factor Targets	1.0	null
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41314
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63487
colistin-4212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AVPR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591554
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	2.36415
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06011
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GMFG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450328
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44898
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.926864
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34853
Lung adenocarcinoma_LUAD_TCGA-78-7150-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8621
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875179
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.73741
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37116
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835237
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78305
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53425
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
guaifenesin-3431	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5224221-956	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26798
GTEX-P4QS-0426-SM-3NMCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91028
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skbr3	HPA Cell Line Gene Expression Profiles	1.0	1.09748
lycorine-4365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
UACC-812	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890023
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
18223198-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21138
NCI-N87	GDSC Cell Line Gene Expression Profiles	1.0	2.35145
genistein-268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE87404,GSE87812_2_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
clenbuterol-4671	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87033
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941043
MHHES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06906
CRCGN017_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04949
MRPL46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56171
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944846
TMA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31861
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050724
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tanespimycin-5578	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6143
KP2	DepMap CRISPR Gene Dependency	1.0	2.42619
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44851
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935585
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Y-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20519
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28669
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31517
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69252
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
altered susceptibility to bacterial infection	MPO Gene-Phenotype Associations	1.0	null
GTEX-QDVN-1026-SM-48TZA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869069
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32511780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17314
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	0.829619
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19148
BRD-K82292504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25694
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51059
sulfathiazole-4183	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant-5964	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.08822
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
thioridazine-6989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE236502_2_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951552
clofazimine-4682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.4166
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.27083
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38234
DL-PPMP-1121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_6615_OE_MATR3_SRP132715	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.25631
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.984136
wortmannin-977	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2595
hsa-miR-661	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
BRD-K71871382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41501
cloperastine-3608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.97336
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54126
FBXO32	Pathway Commons Protein-Protein Interactions	1.0	null
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22621
alvespimycin-993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE121198,GSE129779_0_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.918075
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856907
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-101-ZNF281_ZNF281	Rummagene Transcription Factor Associations 2026	1.0	null
Left middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00952
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYAE1	DepMap CRISPR Gene Dependency	1.0	4.36899
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06846
RRBP1	Pathway Commons Protein-Protein Interactions	1.0	null
ethambutol-4001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16168
Sepsis_Splenocyte_GSE4479	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.69161
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203308_8_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92324
BRD-K90644597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5053
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
guanyl-nucleotide exchange factor activity	GO Molecular Function Annotations 2025	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.85196
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR2_targets-genes_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.275
BRD-K58643762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03357
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32697
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3971
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40341
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59568
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837906
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7058
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4658	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12347
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25983
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19182
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10676
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887223
BRD-K15400067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13526
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840464
BRD-K98153780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04827
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37606
ikarugamycin-918	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4639-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62237
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prestwick-1103-6019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4292	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Perturb_14530_KO_Nr5a2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83896
BRD-K24962261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20031
hsa-miR-19b	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67378
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
15-delta prostaglandin J2-6990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_4636_KO_lnc956_SRP359638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11089
RT112	CCLE Cell Line Gene Expression Profiles	1.0	1.35212
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70794
GSE200839,GSE233826_2_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902831
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.87258
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23235
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.886793
BRD-K57182060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36446
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3619-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36506
BRD-K29366596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4267
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69466030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16303
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-302a	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835079
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44249
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8153
debrisoquine-6688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6236
BRD-K60806315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22274
COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	3.20664
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4009
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.74725
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31625
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939037
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16956
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52603
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
calmidazolium-486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NB10	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49806
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33545
BRD-K09144377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2931
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00869173
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
nordihydroguaiaretic acid-6942	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60132
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.932379
MCF7_Sirtinol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139355
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39466
BRD-K61354976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27157
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9528
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10929
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.23308
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K07385991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52903
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11627
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36827
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SYK_KD_GDS3609_440_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904642
Charcot-Marie-Tooth disease type 4D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
BRD-K31884664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19871
monorden-1644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-708	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
KMRC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69975
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKCO1	CCLE Cell Line Gene Expression Profiles	1.0	1.65693
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992418
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27729
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956265
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13471
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.25689
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31441
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F4-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840391
Lung adenocarcinoma_LUAD_TCGA-97-A4M5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871647
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9841
GSE186767_1_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.101
norcyclobenzaprine-4190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10042887-41419_2023_5742_MOESM3_ESM.xlsx-Table_S3-Table_S3_Differently_expressed_genes_in_HOXB3_vs_HOXB3-_aPCA_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
esophageal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18114
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987918
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.50785
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50774
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-115-ZNF776_ZNF776	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02633
Lung adenocarcinoma_LUAD_TCGA-73-4675-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67665252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82716
MCF7_ENMD-2076_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118567
BICR56	DepMap CRISPR Gene Dependency	1.0	5.0245
CRCGN015_MCF10A.WT.HP_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2499
hsa-miR-624	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
SNU899	CCLE Cell Line Gene CNV Profiles	1.0	1.53694
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37442
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30037
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47139
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-302c	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01805
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02002
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01244
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876832
MAF-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HuP-T4	GDSC Cell Line Gene Expression Profiles	1.0	1.85894
0225151-0000-6389	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39204
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08281
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ARAF	Pathway Commons Protein-Protein Interactions	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.074
3-acetamidocoumarin-4601	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC8803621-mmc5.xlsx-54JIB-04genes_w_GATA4_motif-GATA4_Q3_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63702
GSE193993_5_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23004
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969982
BRD-K75416889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46755
hsa-miR-370	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03703
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72262
BRD-K21622447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02796
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8302
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
metformin-4	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27668
Perturb_7626_KD_UPF1_SRP120604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25229
PMC11551338-pnas.2411189121.sd01.xlsx-PXR-Unnamed_0_NR1I2	Rummagene Transcription Factor Associations 2026	1.0	null
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	0.979956
esculin-5411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.5757
cetirizine-4231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K18865369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95531
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01244
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.83031
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.483
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12083
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66649
Pancreatic ductal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2101
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83125173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65366
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26297
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.19816
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85172
AVPR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599406
MCF7_Luminespib_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0108766
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.51875
MCF7_SNS-314 Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119534
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38338
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29896
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LY-294002-6976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE232631_5_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18267
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1692
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.899827
metformin-1858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60558
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999426
GSE117045_3_v_2_amphetamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10295
lumicolchicine-4195	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70061
GSE153189_2_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small GTPase-mediated signal transduction	GO Biological Process Annotations 2025	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53242
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19101
HCC827GR5	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09206
folic acid-2783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3456
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07182
GTEX-S32W-1026-SM-4AD5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53875
amygdaloid complex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.967278
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4534
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9316731-13059_2022_2728_MOESM2_ESM.xlsx-S3_AlternativeTSS_ZF-D3A-wt-Gene_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
chlorpromazine-6936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02702
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GBX1_GBX1	Rummagene Transcription Factor Associations 2026	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.08014
Sarcoma_SARC_TCGA-QQ-A5VD-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
butyl hydroxybenzoate-5608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31206
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.939123
flucloxacillin-5102	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PPAP2C	Pathway Commons Protein-Protein Interactions	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02862
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15226
BRD-K76803075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13696
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32596
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TE5	DepMap CRISPR Gene Dependency	1.0	2.87817
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
troglitazone-6949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.98701
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39594
BRD-K20829034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01036
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.843744
cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K11585900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47232
naftifine-7032	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61296
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22471
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056075
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08569
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59184
GPX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00727904
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.939123
Perturb_4897_KD_U2AF1_SRP160510	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.96774
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42757
hsa-miR-22	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27994
ETS1	ENCODE Transcription Factor Targets	1.0	null
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.848513
hydrocortisone-6684	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PQ-1526-SM-3NMCK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21012
SKOV3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12312
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95771_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KKU213	DepMap CRISPR Gene Dependency	1.0	2.53831
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16169
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8756
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12156
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
PMC11694450-Table_1.xlsx-MR_to_MM_at_2_DPI-Supplementary_Table_1_1_Differentially_expressed_genes_in_the_cecal_tonsil_transcriptome_in_the_M_R_group_compared_to_the_M_M_group_at_2_DPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.86736
spectinomycin-4187	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37339
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09191
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995819
BRD-K81821040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34906
CRCGN008_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1787
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53814
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
T3M4	CCLE Cell Line Gene Expression Profiles	1.0	1.53392
3-acetamidocoumarin-7361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Altretamine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135397
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09073
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63693
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03647
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911907
Perturb_7628_KD_HNRNPL/UPF1_SRP129007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.06893
PMC4792926-ncomms10810-s3.xlsx-list_2_PHF20-dependent_E2_genes-gene_PHF20	Rummagene Transcription Factor Associations 2026	1.0	null
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218715
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09821
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.47629
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27387
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903847
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10295
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.4318
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22289
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81486
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22013
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0486
GSE202434,GSE202438_7_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79256
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15928912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92712
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885139
CAL33	CCLE Cell Line Gene Expression Profiles	1.0	1.92965
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.71892
Prestwick-967-4250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9052
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14183
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84242
BRD-K43205312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09031
tetrahydroalstonine-6209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964399
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07412
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46048
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32596
BCAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554613
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5767
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18575
molindone-4199	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-520g	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
HUTU-80	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CREB1-26743006-CHIP-SEQ-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33078666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10651
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81509
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833407
MCF7_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170302
BRD-K20091931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20094
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_219_OE_LINC01133_SRP394296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
small gtpase mediated signal transduction	GO Biological Process Annotations 2015	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BL-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02931
LY-294002-1652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94775
hsa-miR-3180-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51568
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A5QV-01A-22R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856011
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5629-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07485506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42696
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00566
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12643
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.964569
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ABC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.54599
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00692186
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.11095
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22702
Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16081
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29079
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12248
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
RPS16	Pathway Commons Protein-Protein Interactions	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.96221
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53279
rolipram-6730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT-112	GDSC Cell Line Gene Expression Profiles	1.0	1.75717
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909956
hexestrol-2515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03807
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26919
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00818
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15306
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06129
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54922310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51119
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7275
NU-1025-313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05269
CLIC1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5282
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43232
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1236
tanespimycin-5586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-296-3p	MiRTarBase microRNA Targets	1.0	null
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.21799
A2058	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67144
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4708
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23114
EFM192A	CCLE Cell Line Gene CNV Profiles	1.0	1.71308
ifenprodil-7404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:F08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06364
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23114
A172	CCLE Cell Line Gene Expression Profiles	-1.0	-2.43788
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4253	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
skin	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hsa-miR-761	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
bj	HPA Cell Line Gene Expression Profiles	-1.0	-0.947043
hsa-miR-4732-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47346
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40451
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71385
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
macromolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NCIN87	DepMap CRISPR Gene Dependency	1.0	2.54646
fulvestrant-1630	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.993487
isosorbide-4742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.41937
EGR1	ChEA Transcription Factor Targets	1.0	null
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48816
BRD-K67194214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30558
BRD-K98976117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34528
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85172
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64549
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11785
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.901646
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5593
BRD-K30038014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15567
SNU503	CCLE Cell Line Gene Expression Profiles	1.0	1.7552
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	1.3691
Polymeric cytoskeletal fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28001
ANLE-138B	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00516
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18229
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
BRD-K22846014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22342
Ramos-2G6-4C10	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55469
estradiol_homo sapiens_gpl6947_gse27375	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08941
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48752
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TE4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77991
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964935
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
riboflavin-2760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31876
hsa-miR-532-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3188
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6384
HAO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492685
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.19746
Prestwick-689-6076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESR2-21235772-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21482
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900044
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00717406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39297
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73459389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26217
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5534
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862963
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17699
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-Unnamed_1_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-520f	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09758
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47677
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7375
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.68698
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14873
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.75113
BRD-K93044218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00327
equilin-3039	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35274
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.5246
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31556
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13855
BRD-K11942486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13018
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
BRD-K61555339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55448
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24234
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0317
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62911
fulvestrant-5598	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG7-2326-SM-3GIKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36726
hsa-miR-302e	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
metolazone-6292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XV7Q-1226-SM-4BRVT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05077
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.883334
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90301
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00952
corticosterone-3244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03776
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.940284
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
HS274T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69086
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2228	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6913
hsa-miR-4640-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-320a	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
ICC9	DepMap CRISPR Gene Dependency	1.0	3.88374
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26586
BRD-K15028515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10609
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17951
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864756
CKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00654329
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19032
BRD-K23481525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09995
octopamine-3112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89354
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19881
tretinoin-6931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24596
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EXOC3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37169
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890023
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864556
DYRK1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619311
Perturb_16731_KO_Myc/Pin1_SRP069191	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.39935
Esophageal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31505
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11557
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4726-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
hymecromone-4623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917277
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849745
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.907655
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23328
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70917
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0764
EW-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62147
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K55640577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16662
meclofenoxate-4268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.6277
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08135
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO3	ChEA Transcription Factor Targets	1.0	null
Perturb_7293_KD_U2AF35_SRP116787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.79841
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967605
GTEX-P78B-1026-SM-3NMC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965055
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27664
carbachol-6742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-566	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-608	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987946
hsa-miR-28-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87166
Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5264
CRCGN017_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.89747
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4935
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843273
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
BICR6	CCLE Cell Line Gene Expression Profiles	1.0	1.42513
amylocaine-4089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36028
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04796
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44851
AOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00427754
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97231
STAP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21742
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35065
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26396
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15242
BRD-K66734120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71902
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trimethylcolchicinic acid-4202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
clofibrate-444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUN_01_291	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.69522
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13317
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	1.0	2.1572
ABCC3	Pathway Commons Protein-Protein Interactions	1.0	null
(-)-MK-801-5003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2170	CCLE Cell Line Gene Expression Profiles	1.0	2.09026
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.15408
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.15546
CAPN5	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972078
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.996347
urapidil-6696	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54F-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27057
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45966
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7342
ZNF384	ENCODE Transcription Factor Targets	1.0	null
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01471
thioperamide-3055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956606
SH10TC	CCLE Cell Line Gene CNV Profiles	1.0	1.52372
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00236
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K84239940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92278
7-aminocephalosporanic acid-4242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0976
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16192
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.75045
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2030	CCLE Cell Line Gene CNV Profiles	1.0	1.39425
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MKN7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07759
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91812
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11563
H3K36me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system development	GO Biological Process Annotations 2015	1.0	null
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14797
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00759
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916054
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909057
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SF-0926-SM-4AD4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03178
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13339
nafcillin-3983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
velnacrine-6651	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gelsemine-2162	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-642a	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9346
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837151
heliotrine-4277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AGR2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930213
GSE158834_2_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09663
hsa-miR-1224-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38980456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04773
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K34604637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11152
colon_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.966253
Perturb_7994_KO_Tet2_SRP062557	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.18014
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51292
REST	ENCODE Transcription Factor Targets	1.0	null
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178292_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_610_KO_SLFN11_SRP233181	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.22591
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88367
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66821
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.00686
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.9437
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
altered susceptibility to infection	MPO Gene-Phenotype Associations	1.0	null
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48866
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
simvastatin-4244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-520h	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
fluvastatin-3032	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60801
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60132
ESR1-30970003-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.41365
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.962
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
atractyloside-2573	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83597
Lung squamous cell carcinoma_LUSC_TCGA-60-2716-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basomedial nucleus (accessory basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831001
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137914_0_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41842
UACC-893	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.04037
ALDOA	Pathway Commons Protein-Protein Interactions	1.0	null
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84353
BRD-K53335788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15928
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68884923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66898
noscapine-2745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19847
CAL-33	GDSC Cell Line Gene Expression Profiles	1.0	1.56153
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13327
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23114
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59447
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
pyrithyldione-2740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
estradiol_homo sapiens_gpl571_gds4063	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
glycocholic acid-6716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nuclear part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04566
flucytosine-6690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_A-366_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158489
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
metformin-1	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04318
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skmel30	HPA Cell Line Gene Expression Profiles	-1.0	-1.09596
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESR1-22217937-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K48611791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32425
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
r7 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06676
foliosidine-2201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ESR1-21235772-MCF-7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cefalotin-6079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.52755
DOK	DepMap CRISPR Gene Dependency	1.0	4.32182
hydroxyachillin-4213	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40423
WHSC1	ENCODE Transcription Factor Targets	1.0	null
SOX2-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43608
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7435
HSD17B3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939937
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Phosphatidylinositol 3-kinase complex, class II	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.098
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prestwick-860-3040	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NB4	Achilles Cell Line Gene Essentiality Profiles	1.0	1.92408
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60839
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32801
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10884
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03506
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55455
nalbuphine-7177	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07385
BRD-K02159857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25585
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.878077
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839829
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL24	DepMap CRISPR Gene Dependency	1.0	2.41558
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97113
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38047
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38053
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
BRD-K73994499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00253
19605494-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAOS2	DepMap CRISPR Gene Dependency	1.0	2.15134
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.68928
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07756
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847908
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19159562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3822
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1613
CHP212	CCLE Cell Line Gene CNV Profiles	1.0	1.58338
HCC56	DepMap CRISPR Gene Dependency	1.0	2.04843
hsa-miR-583	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
ROS-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dirithromycin-7446	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.47677
CRCGN017_MCF10A.WT.HP_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6089
dienestrol-6208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sirolimus-2702	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61165
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973003
Prostate adenocarcinoma_PRAD_TCGA-HI-7170-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19766710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07719
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0079
hsa-miR-520c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
TAGLN	Pathway Commons Protein-Protein Interactions	1.0	null
H3K36me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6844-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23722
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95507
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45307863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10984
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.308
CAB39L	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08126
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.846008
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3902
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70143
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.931248
papaverine-6245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040053
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53681
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.04299
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35648
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91799761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96224
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19957
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07634
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate-hillock cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	0.747046
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83665
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	1.4362
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83448282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13108
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922709
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09102
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LN319	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.47788
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	4.1285
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01626
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958331
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43451
naringenin-4422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
flunarizine-7013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ELP6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36886
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16606
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907461
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7263-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF701	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13122
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01381
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28287
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Prednisone_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135839
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77679
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17951
lorglumide-5254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26529
BRD-K73899967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40007
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09293
e21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.7535
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39203
Perturb_13716_KO_BAP1_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.10579
PMC10290283-biol-2022-0622-sm3.pdf-350-NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58112
Gigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22176
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESR1-20079471-T-47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35924
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.56024
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.947058
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20666
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904198
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4887
BRD-K68580555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4799
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01556781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40459
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39581
testosterone-5271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921873
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43632
bisoprolol-5348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OOBJ-0426-SM-3NB1S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25217
GSE233566_1_v_2_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A48N-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-320d	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
Lung squamous cell carcinoma_LUSC_TCGA-94-A4VJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.15324
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10866
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE143662_3_v_1_dcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16561
EOMES-21245162-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sotalol-7338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1083
CAPAN-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
MCF7_Sodium Phenylbutyrate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159773
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.16137
BRD-K71415389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86237
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62663
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0526-SM-3MJHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.897182
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050827
CBX3	ENCODE Transcription Factor Targets	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5443
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90301
BRD-K01980291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47314
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04177
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03985
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15951
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
norcyclobenzaprine-2830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
flavoxate-7405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2233
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QF-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59013
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848071
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.048
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82842087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14908
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81204
prasterone-6673	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3049
STAT3	ENCODE Transcription Factor Targets	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.952239
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45689
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.27458
BRD-K97951470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07308
BRD-K98790311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08114
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2951
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41145
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3413
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894796
VAMP8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orphenadrine-2356	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K09699976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59394
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907399
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6930440-jcav11p0520s3.xlsx-MI_vs_FG-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39036
BRD-K34886590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25218
F5	DepMap CRISPR Gene Dependency	1.0	3.66143
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955653
APP	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_7576_KD_ZC3H4_SRP343726	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.6936
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23133
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6022
PMC12304111-41598_2025_13196_MOESM5_ESM.xlsx-Sheet_1-Table_S4_DEGs_Log2FC_1_and_p_adj_0_05_in_pancreatic_cancer_with_high_versus_low_OVOL1_expression_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1260b	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12792
KYSE-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39079
Microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18737347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72237
tanespimycin-1651	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28336
HMGN3	ENCODE Transcription Factor Targets	1.0	null
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18136
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82721
trifluridine-7176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48411
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.61971
reserpine-4203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10454
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2758
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05725
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CSTB_KO_GDS5091_23_mouse_cerebellar granule	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7176
hsa-miR-4758-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
Perturb_13962_OE_ecircCUX1_SRP333026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16974
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70064
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6896
ergocalciferol-6746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74314
Prestwick-685-2188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
levonorgestrel-2547	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4024
NCIH2106	CCLE Cell Line Gene Expression Profiles	1.0	1.55245
Perturb_17685_KO_Pgr_SRP365149	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
intermediate stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02702
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94133
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15016
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73430970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38225
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60774
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.718108
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
trifluoperazine-6984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
etodolac-7006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Busulfan_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145656
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840571
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77940693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24489
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986061
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1183
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13327
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835764
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25265
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-A5GW-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.15546
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22947
BRD-K08458391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08138
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.465
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33166
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.977977
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nizatidine-6305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06145
loperamide-4672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15485
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872103
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PX-01A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1623
CAOV3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47325
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10573
PTP4A2	Pathway Commons Protein-Protein Interactions	1.0	null
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3536
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913849
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57448
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01087
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
esophageal squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.54295
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
0198306-0000-7099	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949459
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02021
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19602
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.703112
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.29267
Perturb_6591_KO_Zcchc8_SRP187429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.1565
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4136
GSTP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08755
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07447
BRD-K43108627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02207
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00182
GTEX-U412-2026-SM-4DXSI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868344
mRNA_SMARCA4_22196727	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19967
BRD-K60895802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10272
raloxifene-6235	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901511
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LGALS4	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.965161
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23739
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15485
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71359
GTEX-R55F-0126-SM-48FCK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873777
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
Meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40084
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137914_4_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979854
Z chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.00771
hsa-miR-4696	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18057
ALDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48602
BRD-K52218664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40262
BICR31	CCLE Cell Line Gene CNV Profiles	1.0	1.7589
DMS454	CCLE Cell Line Gene Expression Profiles	-1.0	-3.53385
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7629_KD_UPF1_SRP129007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25229
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850897
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02741
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TE5	CCLE Cell Line Gene Expression Profiles	1.0	1.3574
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE139348,GSE139349_1_v_0_dicer1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51442
trimethadione-2486	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68556
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17767
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57218
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1113
GSE98898_4_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
benzbromarone-6669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16408
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09299
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5617
harmine-7209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K56618252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85649
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968999
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5221
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.22894
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K10343715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31688
BRD-K45936761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16516
BRD-K36575476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45678
BRD-K07197565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41037
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3595
BRD-K14122415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51791
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1286
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
alclometasone-2532	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PL45	CCLE Cell Line Gene CNV Profiles	1.0	1.37766
Perturb_3450_KO_Cnp_SRP073495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.1451
GSE94849_6_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.970343
monorden-1057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954919
TP63	ChEA Transcription Factor Targets	1.0	null
GSE120612_7_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7275
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07977
GSE190384,GSE190386_6_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1692
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09483
NCIH838	Achilles Cell Line Gene Essentiality Profiles	1.0	1.20654
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8652
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11098
kidney_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.18916
BRD-K65314728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14944
BRD-K68676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08217
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02209
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
LS411N	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.01776
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58855
PHA-00745360-4562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54172
Ubiquitin-related domain	InterPro Predicted Protein Domain Annotations	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10196
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59767
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-29a	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989816
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47677
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52335
GATA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825588
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9333
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44589
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922031
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27912
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TC32	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69846
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37379
H357	DepMap CRISPR Gene Dependency	1.0	2.77064
androsterone-4635	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FAM171A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23954
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.19225
hemicholinium-6739	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4318_KD_Fos_SRP075838	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.5452
MCF7_MC1568_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01277
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843553
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54368
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05318
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01592
JIMT1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2471
BICR6	DepMap CRISPR Gene Dependency	1.0	2.0245
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
P32-ISH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06459
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914892
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50245
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05859
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0583
Esophagus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.78474
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HQ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14253
BRD-K05699155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25896
hsa-miR-4496	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
BRD-K16214172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35111
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33586
CRCGN015_MCF10A.WT.HP_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15897
ESR1-21235772-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1693	CCLE Cell Line Gene CNV Profiles	1.0	2.12193
benperidol-4196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052196
Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.873211
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33679
EFM-19	GDSC Cell Line Gene Expression Profiles	1.0	1.47448
Perturb_12094_KD_Cdkn2a_SRP169507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MCF7_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0102571
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1291_KO_Lef1/Tcf7_SRP111197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10642
hsa-miR-485-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE193993_5_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14118
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7219
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A27C-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.890263
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49185
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRK-1426-SM-3NB19	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04576
CRCGN016_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.95528
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.992814
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.863142
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4475
MCF7_Tucidinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00961156
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
propidium iodide-6277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79913
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nervous system development	GO Biological Process Annotations 2025	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.10294
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11251
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K39037393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70918
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_13717_KO_BAP1_SRP360138	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.43682
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.95064
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7475
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13631
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
apigenin-4578	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-1103-3540	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28513
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
PMC11551338-pnas.2411189121.sd01.xlsx-FXR-Unnamed_0_NR1H4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_1_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.93827
hsa-miR-370	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ESR1	ChEA Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935459
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A2QG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0573
hsa-miR-4429	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
BRD-K48845054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50196
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048807
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
rectum	HPA Tissue Protein Expression Profiles	1.0	1.15546
MKN45	DepMap CRISPR Gene Dependency	1.0	3.2743
BRD-K21124684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16386
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12792
CSF1R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548885
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
butyl hydroxybenzoate-4647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18165
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.23258
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE202434,GSE202438_4_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.736
GSE134375_6_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
18387200-Genes	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90692
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.973962
PMC6545035-12943_2019_1031_MOESM7_ESM.xlsx-Sheet1-Supplementary_table_5_The_significant_reduced_genes_in_TET1_knockdown_cells_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15967
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77679
hsa-miR-520a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15432
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIMA	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48961
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62232
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.879477
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09155
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
carbamazepine-952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
T3M4	DepMap CRISPR Gene Dependency	1.0	3.14133
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.93633
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05191
prochlorperazine-1640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FCGBP	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K51978501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88284
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
15-delta prostaglandin J2-1656	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07401
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21978
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_4day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.82959
ethisterone-4340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00938
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-300	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
guanyl-nucleotide exchange factor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31321
TE9	DepMap CRISPR Gene Dependency	1.0	3.32884
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835091
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.31143
BECKER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64787
GTEX-WFG7-1026-SM-4LMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22375
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913669
raloxifene-2738	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99001
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K39526528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12812
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931745
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0519
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11402
BRD-K21483524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01516
regulation of gtpase activity	GO Biological Process Annotations 2015	1.0	null
CD40 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.677
BRD-K61629734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43739
Perturb_6910_KD_KLF5_SRP091857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.47616
TLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00508528
system development	GO Biological Process Annotations 2015	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936824
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97401
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914677
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13359
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0443
hexylcaine-2708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14183
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60198
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90586
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34272
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4091
calycanthine-6221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.061
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217442
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LY-294002-1019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48442
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microtubule	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10479
tamoxifen_homo sapiens_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_AT9283_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139358
BRD-K16826857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0359
fluphenazine-7234	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K19344710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14037
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998907
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.12634
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3291
ACO2	Pathway Commons Protein-Protein Interactions	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28128
RCM1	DepMap CRISPR Gene Dependency	1.0	2.59981
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.00195
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60425
emetine-4243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4433-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52149
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46134
AGO1_02_162	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59946
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06517
SARS-CoV MA15_Day7-C57BL6_None_GSE51386	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70752
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30429
BRD-K62753164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02373
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SKES1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57647
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31574
NOX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00463923
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33802
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26752
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKMM2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.13867
PK1	DepMap CRISPR Gene Dependency	1.0	4.66727
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16992
CALU-3	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5802
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46767
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05674
MCF7_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211084
tretinoin-849	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17053
amoxicillin-2620	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
estropipate-6808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluvoxamine-7333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.973008
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K31870622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04263
15-delta prostaglandin J2-6948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41151
BRD-K28165749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0042
pronetalol-3984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01856
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217552_3_v_5_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tretinoin-1049	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15488
Lung adenocarcinoma_LUAD_TCGA-78-7540-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
geldanamycin-1653	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53904
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925465
ciclosporin-602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A51Y-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03059
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11985
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.959848
coralyne-2652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83678
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15959
BRD-K90741031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02904
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SEC61A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.05264
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TE-12	GDSC Cell Line Gene Expression Profiles	1.0	2.24577
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06503
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21955
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16604
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0477
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.61614
hsa-miR-125a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.93137
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2170	GDSC Cell Line Gene Expression Profiles	1.0	1.5412
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCSW1	DepMap CRISPR Gene Dependency	1.0	3.22185
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37216
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969982
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	4.03826
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21511
BRD-K28431554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01737
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60557007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01806
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872098
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15085
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89394
CKB	Pathway Commons Protein-Protein Interactions	1.0	null
AGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11216
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12116
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABARAP	Pathway Commons Protein-Protein Interactions	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.4165
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856011
cefoxitin-3477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
increased thermal nociceptive threshold	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_2392_KD_TRIM28_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.2943
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5378
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06018
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07477
HS578T	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.17854
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840034
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06317
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04798
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28414977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05663
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cinchonine-3988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3103
cytoskeletal part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
naftopidil-4193	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4781-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79561347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36322
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939595
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	2.8587
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3828
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26576
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951235
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968009
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61904
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09338
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10941
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931821
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	1.48418
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.65915
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07044
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40099
lisuride-6682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857899
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59013
SC-58125-254	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
seneciphylline-4238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23272
BRD-K73577714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08845
Perturb_17193_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.643616
BRD-K91137832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18267
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sulfafurazole-4661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_1410_KD_Hsf1_SRP347252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K64788035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2258
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9574
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12705
CRCGN011_HEPG2_24H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5579
EKVX	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56118
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11346
BRD-K59606563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15533
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35924
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58025976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06655
PRKACA_knockout_266_GSE20984	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.75247
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1819
diclofenamide-6686	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16802
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934852
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36925
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC44	Achilles Cell Line Gene Essentiality Profiles	1.0	1.45658
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3467
BRD-K02473319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09458
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU1214	CCLE Cell Line Gene Expression Profiles	1.0	1.36761
BRD-K84233365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0895
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08089
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07977
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3299
hsa-miR-519d	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KC-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTPRH	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16123
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.71598
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
resveratrol-595	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21341
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01514
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.63555
ritodrine-4619	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MCF7_Mocetinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00844418
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92879
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42151
TBP	ENCODE Transcription Factor Targets	1.0	null
Tongue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32477
hsa-miR-520e	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0202
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44352
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48641
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936506
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940628
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986909
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1_01_171	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60116
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0879
colon	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
Tongue	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55313
SNU308	DepMap CRISPR Gene Dependency	1.0	3.41425
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.65197
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44762
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15485
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20781
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.64257
BRD-K45609222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21003
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88887
NDRG1	Pathway Commons Protein-Protein Interactions	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGKC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825056
BRD-K72314068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34635
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	1.26173
hsa-miR-520a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41712
saquinavir-6246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20111
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2592
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
POLR2A	ENCODE Transcription Factor Targets	1.0	null
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44851
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.76958
Prestwick-857-3016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LN443	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0359
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
paclitaxel-6720	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.782347
Kidney Chromophobe_KICH_TCGA-KN-8427-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.01337
DM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74275
BRD-K74475430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6292
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6037
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67448
BRD-K38929751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2186
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PCDH12_Deficiency_GDS3415_577_mouse_Embryonic placentas (12.5 day)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875483
Perturb_2391_KD_PRKDC_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.96411
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.949797
trichostatin A-413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-19a	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16956
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62232
BxPC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.47155
GTEX-P4QS-0726-SM-3NMCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71338
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42R-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38679
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09102
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ME-180	GDSC Cell Line Gene Expression Profiles	1.0	2.369
BRD-K33200274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18635
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59165
estradiol-5238	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22386
GTPase regulator activity	GO Molecular Function Annotations 2025	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2513
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR5A2_01_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.69181
BRD-K28431799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31718
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.40966
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908635
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14118
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01671
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23915
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	1.0	1.87309
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1113
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860473
tanespimycin-1063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K36me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28427
HCC2218	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.34364
tretinoin-6971	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K18601936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03358
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81512
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K66748326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11367
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966123
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07094
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03539
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.975301
BRD-K11165361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30191
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22879
UACC-893	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952971
GSE126127_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34087
NFIC	ENCODE Transcription Factor Targets	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.058
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15367
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08171
posteroventral (inferior) parietal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.998966
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	1.53832
Perturb_15480_OE_ERG_SRP075246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00459
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19314
OVCA420	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
BRD-K39543844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29572
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6222
epiandrosterone-4626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K85977570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04253
NCIH2170	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
acetylsalicylic acid-6924	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.555
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73275
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9489
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2013
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	1.0	3.00003
sulconazole-6652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K31960013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59881
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921641
A431	DepMap CRISPR Gene Dependency	1.0	3.81437
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.982895
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18004653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09887
MCF7_Decitabine_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135747
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949476
MCF7_Thalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150754
MCF7_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161045
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31556
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4580625-pone.0138726.s006.xlsx-Immune_molecular_modules-STAT5B_mod_STAT5B	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rolitetracycline-6731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCLY	ChEA Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KR-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SHMAC4	DepMap CRISPR Gene Dependency	1.0	2.07167
DES	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14256_KO_FOXO3_SRP221507	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40693
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.07518
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99189
Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78027
BRD-K23467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04467
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20961
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23383
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Supramolecular fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14118
t47d	HPA Cell Line Gene Expression Profiles	1.0	1.69254
hsa-miR-4711-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95972
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ioversol-3026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-372	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2965
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5283
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01761
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50998
BRD-K04266880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23548
Perturb_17179_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.5376
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54061
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19781
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2994
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925548
ketoprofen-3626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12782513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35104
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11659402-41523_2024_709_MOESM3_ESM.xlsx-Sheet2-ESR1_mutation_E2_Co-UP_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48893
A361	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
promethazine-6717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21368
BRD-K03376048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18996
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41542
TE9	CCLE Cell Line Gene Expression Profiles	1.0	1.78865
TAF1	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43957
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mestranol-4208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.65856
levamisole-7450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863759
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17951
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932189
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSB	Pathway Commons Protein-Protein Interactions	1.0	null
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72562
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39552
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-let-7c-5p	MiRTarBase microRNA Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6223-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
betonicine-2207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28357534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33045
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18285
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04269
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935492
MTA3	ENCODE Transcription Factor Targets	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22882
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06963
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09294
F36P	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00172
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84705
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193351_1_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_0_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
progesterone-6646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08534
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79714
REH	Achilles Cell Line Gene Essentiality Profiles	1.0	1.71142
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13161
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.052
BRD-K96560179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04915
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20316
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0834
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.483985
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43854
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06145
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69572
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20185935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40509
MCF7_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017189
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92835
ventrolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.827727
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55402
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.958437
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31917
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23801
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0697
theobromine-2995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-486-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
TXN2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tolazoline-4262	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.934726
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.01928
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01494
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.66366
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831515
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE8	DepMap CRISPR Gene Dependency	1.0	2.66756
BRD-K31716785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5974
FOXA1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90519599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48764
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2113
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97448
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
zidovudine-6733	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892155
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X88G-0426-SM-47JZ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05267
BRD-K17705111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79901
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
econazole-6008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
bacampicillin-4592	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
canavanine-4197	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12646
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12506
BRD-K10416099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0466
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7187
kidney	HPA Tissue Gene Expression Profiles	-1.0	-0.85816
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.893524
spironolactone-6255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3446
Perturb_15485_KO_TET2_SRP188574	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.59358
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81959
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16539
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.981959
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCT15	BioGPS Cell Line Gene Expression Profiles	1.0	1.23646
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08133
enoxacin-4655	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72945
BRD-K99335646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11998
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2170	DepMap CRISPR Gene Dependency	1.0	4.56324
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAL-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013284
intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59978
TRIM23	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus-5239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43X-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6742-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33414
ursodeoxycholic acid-3105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994148
Perturb_5605_KD|OE_METTL1|RPTOR_SRP312040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Fetalbrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959722
Guanosine monophosphate	HMDB Metabolites of Enzymes	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60154
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08491
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1151
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
COLO783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.30155
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
N6-methyladenosine-6732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
roxarsone-5470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE145476_1_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.39458
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
droperidol-4629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49872883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14638
bisoprolol-6748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
esophagus	GTEx Tissue Gene Expression Profiles	1.0	0.86294
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15896
BRD-K71574401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05934
PMC11297914-41389_2024_531_MOESM1_ESM.pdf-245-GRHL3_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
desipramine-5292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47497
hsa-miR-4280	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19336
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51649
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80979
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18353
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09878
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
mecamylamine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22011
monobenzone-6713	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5872
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VPS51	Pathway Commons Protein-Protein Interactions	1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00368
methylergometrine-6704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956449
NANOG	ChEA Transcription Factor Targets	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2964
Perturb_17679_KO_l2LsL_SRP228817	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cefapirin-2730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
delsoline-2513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21327
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53819
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83187
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4289
nilutamide-6763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28279
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP2K6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.49652
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3409
Ras guanine nucleotide exchange factor domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE80819_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-568	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ras protein signal transduction	GO Biological Process Annotations 2023	1.0	null
nervous system development	GO Biological Process Annotations 2023	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTGDS	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.701
resveratrol-5509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ANXA6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.564
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0284
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
ESR2-21235772-MCF-7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1692
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46939
CSTB_KO_GSE47516_132_mouse_granule neurons	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54546
procainamide-4602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85595
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03647
BRD-K02066524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16888
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75568
GSE121198,GSE129779_0_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
SGF29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06529
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Supramolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943883
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.0112
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0671
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_41_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2933
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0248
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.922709
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52391
BRD-K50976856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40151
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18866
Perturb_9270_OE_Lin28b_SRP217867	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.5624
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
C32	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45147
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LN235	DepMap CRISPR Gene Dependency	1.0	2.5445
BRD-K92950328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68735
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09043
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deferoxamine-3417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LBP9  (Tcfcp211)	MotifMap Predicted Transcription Factor Targets	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2328
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33823
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23481
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13355
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60984
AIFM1	Pathway Commons Protein-Protein Interactions	1.0	null
fulvestrant-5235	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC4792926-ncomms10810-s3.xlsx-list3_G9a_PHF20-overlaps-gene_PHF20	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.6887
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848456
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51884
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
butyl hydroxybenzoate-5245	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K46897949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55531
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endometrial Neoplasms	CTD Gene-Disease Associations	1.0	1.05757
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8811
hsa-miR-4717-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K88996011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12735
Signal recognition particle, endoplasmic reticulum targeting	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00159
metergoline-6744	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94540403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7297
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60063
GSE126776_2_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.83101
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.681
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.923815
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66186
immune system phenotype	MPO Gene-Phenotype Associations	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15160697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05029
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44332
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	2.00539
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50971
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46843
Perturb_6572_KO_Gls_SRP338093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.52852
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.55981
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02211
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95088
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-20a	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
BRD-K35386584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04126
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21924
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17638
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_12147_KD_USP22_ERP116853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1692
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900392
ZNF263	ENCODE Transcription Factor Targets	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853219
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.934434
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871222
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61242
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40849
dimethadione-4607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-FX-A3NK-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04584
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-93	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860048
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX47	Pathway Commons Protein-Protein Interactions	1.0	null
tongue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39546571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18161
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05902
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K62657501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12065
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01171
SELENBP1	Pathway Commons Protein-Protein Interactions	1.0	null
thioperamide-5270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KAT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534821
GTEX-T6MO-0626-SM-4DM6P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24482
MCF7_AT9283_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126119
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921146
PMC11329632-41419_2024_6969_MOESM3_ESM.pdf-9-TBX3_TBX3	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54186
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D4-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11257629-media-3.xls-Dong_et_al_2023-Comparision_of_METTL3_KD_DEG_with_Dong_et_al_GRGs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
rectum_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.906334
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6867
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94672
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992233
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26216
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07204
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30589
H3K36me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IL20RA	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.74902
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03265
Microtubule	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
repaglinide-5862	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_8_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
chr17_40217879_G_T_b38	GTEx eQTL 2025	1.0	3.04134
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cyproheptadine-6740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-525-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00979
BRD-K21040167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73318
decreased susceptibility to infection	MPO Gene-Phenotype Associations	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12649
BRD-K36812047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72265
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3714
BRD-K43979194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10643
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39243
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12792
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17543
Perturb_14529_KO_Gata4/Nr5a2_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.6968
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19881
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25161260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38225
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SLC19A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052868
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148692,GSE148695_7_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE200352_10_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6814
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32819
MAZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77232
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55334
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38183
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32936
crotamiton-3050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
hecogenin-2716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25145
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932946
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05962
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10382
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88402
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51401
loracarbef-5492	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53945
BRD-K71808107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65156
telenzepine-7419	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75956
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40803
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207471_2_v_1_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
r5 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21777
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86229
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20666
fulvestrant-6955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
idazoxan-6747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KYAE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18413
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
geldanamycin-593	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-3.12719
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49849
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16527
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50979
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87087278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32209
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
SW1990	GDSC Cell Line Gene Expression Profiles	1.0	1.8276
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38338
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0356
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.78285
FLNC	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980054
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896708
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50818
PARVA	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-106a	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62365
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31248
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZER1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32801
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
hsa-miR-3664-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARMCX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14733
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883048
diethylcarbamazine-5485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27154
GTEX-OOBJ-1826-SM-3NB1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977556
hsa-miR-520b	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
UACC-812	GDSC Cell Line Gene Expression Profiles	1.0	2.65239
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.9191
BRD-K47443098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54653
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35144
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
SNUC1	Achilles Cell Line Gene Essentiality Profiles	1.0	2.09912
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867856
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR2_filtered-genes_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00985
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27247
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54368
UACC812	CCLE Cell Line Gene Expression Profiles	1.0	3.40791
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88086
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17382
LY-294002-1007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14702
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
etifenin-2477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K91628074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16574
nitrendipine-3087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nifedipine-335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4755-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39581
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136798
nifedipine-603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nisoxetine-5091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96247
Perturb_10709_KO_Ezh1/Ezh2_SRP133172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.35598
BRD-K88051295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29285
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12685
tanespimycin-5223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	HPA Tissue Protein Expression Profiles	1.0	1.15546
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1155
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31556
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885263
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.58936
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87315
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.1663
tropicamide-4280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-214	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
hsa-miR-3916	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43451
corynanthine-4227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28659
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50215
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58147
amprolium-4241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUPM2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64963
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64549
probucol-4666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
niflumic acid-5490	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921641
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.209
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36944891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06964
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910602
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24392
PMC6345883-41598_2018_37397_MOESM10_ESM.xlsx-AR_D0_VS_D7_W_B29__TRANS-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30533
BRD-K84769529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65011
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.25903
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1111
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39068
BRD-K13309514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36879
H3K36me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2084
BRD-K17133642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09414
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	3.00575
CRCGN015_MCF10A_48H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58035
MCF7_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222058
Perturb_17664_KD_TRAF4_SRP292631	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3153	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96977
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4789-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847773
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18583
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.46995
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824087
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CAPAN1	CCLE Cell Line Gene CNV Profiles	1.0	1.57716
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995099
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06804
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32266
TIMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45018
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05279
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.20105
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lasalocid-3021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HKGZCC	DepMap CRISPR Gene Dependency	1.0	2.53814
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833606
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
quinisocaine-2151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61474
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MUC2	Pathway Commons Protein-Protein Interactions	1.0	null
tretinoin-966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC9	DepMap CRISPR Gene Dependency	1.0	2.66964
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_TAK-901_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124704
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAPACHS77	DepMap CRISPR Gene Dependency	1.0	2.63258
PHA-00745360-3827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09121
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXA1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6614_OE_MATR3_SRP132715	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.22921
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893102
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99001
SPHK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578862
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K36726271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29343
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.867436
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10295
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Perturb_12217_KD_EPRS_SRP073504	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.0969
azlocillin-3468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32596
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68885
HKA1	DepMap CRISPR Gene Dependency	1.0	2.42423
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61354849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18025
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61608
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12107
PDE1C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523579
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LY-294002-318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
OACP4C	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13234_KO_Tfe3_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.70069
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6148
pioglitazone-6898	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:M05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26215
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.989415
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.302
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67522096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03907
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fulvestrant-1043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26644
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5809
hacat	HPA Cell Line Gene Expression Profiles	1.0	1.87484
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8361
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.974065
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02967
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29688
allantoin-5471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K18307373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82862
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.90837
trichostatin A-2523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70354
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894005
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51525
ESO26	DepMap CRISPR Gene Dependency	1.0	3.15118
fulvestrant-6997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PSDG-1326-SM-48TD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07069
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04525
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
ciclosporin-4586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11961801-12672_2025_2262_MOESM2_ESM.xlsx-Sheet_1-WGCNA_AND_DEGs_NOT_CSGs_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.87024
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_16531_KO_Cdk8/Cdk19_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.14896
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monastrol-605	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36243
GSE193993_4_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A616-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ras protein signal transduction	GO Biological Process Annotations 2025	1.0	null
Prestwick-967-4833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93040255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93482
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6155
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38313
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05724
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.94035
BRD-K11700411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11324
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.09511
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44129
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5695_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.41218
BRD-K04631545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70982
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34297
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26849
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23547378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00054
thiamine-7479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14957
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92728
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04232710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00953
hsa-miR-3125	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9105
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.2784
quinisocaine-4207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00105
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.51071
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06301
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02706
fulvestrant-7091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
methyldopa-4677	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22302
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888609
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02901
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12323
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82117061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49469
niclosamide-4018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K96170781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84023
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886072
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17151
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38338
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958629
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900354
BRD-K47951859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50376
BRD-K83183082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33271
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13392
MCF7_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017361
disulfiram-6210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984043
selegiline-2465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939686
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
theophylline-4228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5534
hsa-miR-376b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07455
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18764
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.738
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880759
BRD-K06619604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51032
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20505830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07236
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8367
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07426
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866299
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52185
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4755-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
denatonium benzoate-5480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-VDR-Unnamed_0_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-2276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975045
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39388
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34643
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
gliclazide-5089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51568
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14546
MAX	ENCODE Transcription Factor Targets	1.0	null
SW1116	DepMap CRISPR Gene Dependency	1.0	4.60442
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88359
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19584
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.855118
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54704
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828811
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34038
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04177
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0854
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53764
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03267
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of hydrolase activity	GO Biological Process Annotations 2023	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27316
biological_process	GO Biological Process Annotations 2015	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00952
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12867
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21558
Perturb_14143_KO_Cblif_ERP002279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.53874
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927349
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910143
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10295
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22993
Tongue-basal cell	Tabula Sapiens Gene-Cell Associations	1.0	12.6372
hsa-miR-320c	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
nicotinic acid-3381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3428-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18348
Perturb_15482_OE|KD_ERG|EWSR1_SRP075246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.19279
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08061
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987693
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.05926
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.03379
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886129
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12294
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2951
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8795
Lung adenocarcinoma_LUAD_TCGA-05-5429-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35622
PHGDH_KO_GDS2874_125_mouse_embryonic head tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11719
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6448
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3241
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989575
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22289
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25628
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99001
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW837	DepMap CRISPR Gene Dependency	1.0	2.17655
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19731
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48942
signal transduction	GO Biological Process Annotations 2015	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2951
IBMX	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67654
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD23B	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-302b	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PECAPJ49	DepMap CRISPR Gene Dependency	1.0	2.36023
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pizotifen-5491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hyoscyamine-5524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.917827
SLC25A23	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2544_KO_OVOL2_SRP347819	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841054
BRD-K16331797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01817
BRD-K95129711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3016
H3K36me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45401
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993068
arachidonyltrifluoromethane-594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3191
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76915
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.47888
A204	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16194
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.17145
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02552
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12852376-SupplementaryFile1.xlsx-Supplementary_Table_S4-Analysis_of_the_association_between_QTL_and_iridocyclitis_using_MR_and_SMR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TML8-1526-SM-4DXUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887169
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10236
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39581
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9629
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
decreased susceptibility to bacterial infection	MPO Gene-Phenotype Associations	1.0	null
BRD-K60306319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46855
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94402
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12799
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04894
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3796
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3515
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25205
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.837931
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
methapyrilene-6644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
haloperidol-5638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ASS1	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64651
wortmannin-869	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2_Deficiency_GDS4853_321_human_AZ-521 gastric cancer (GC) cell line - 18 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NDUFS8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169356_2_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26758
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879312
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923304
MATH1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-381	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
PMC12410147-NIHMS2099518-supplement-3.xlsx-z-scores_DEGs_DGATi_LPS_vs_LPS-Z-scores_for_genes_differentially_expressed_when_comparing_DGATi_LPS_treatment_to_LPS_alone_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Meningioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esr1_21713035_mcf7_lof_human_gpl570_gds4061	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.53395
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932983
hsa-miR-302d	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
BRD-K80185984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33257
hsa-miR-125b	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
LIPT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0054184
UBTF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77378
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95302_1_v_4_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
propranolol-6759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40185
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
VCAP	Achilles Cell Line Gene Essentiality Profiles	1.0	1.507
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90159
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74483
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39011
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56138
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25553
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04064
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.896431
Supramolecular polymer	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.562
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1692
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56806
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FW-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16276
protein complex	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855223
GSE81193_3_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.48575
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90035
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2722-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.869375
Ras guanine-nucleotide exchange factors catalytic domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11017
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GSE238116_3_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39079
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
MCF7_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00907435
Prostate adenocarcinoma_PRAD_TCGA-CH-5743-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_PF-3845_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156349
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.66043
19174476-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K11979048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23195
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
butamben-2531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
thalidomide-606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39493
PMC4060771-170289.f1.pdf-677-ASCL2_ASCL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTPase regulator activity	GO Molecular Function Annotations 2023	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2396
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.854234
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.274
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.71512
BRD-K41504921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20807
PMC8497275-41388_2021_1985_MOESM9_ESM.xlsx-ER_targets_ER-SRC3-RAC1_sites-Gene_Name_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
proscillaridin-4404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56895
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53241
LY-294002-6935	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00705
corynanthine-2786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13937
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.863871
IRF7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00458044
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
leflunomide-2539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09208
NCIN87	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14682
prednisolone-265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28513
N6-methyladenosine-2626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01969
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14118
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71225
Guanosine triphosphate	HMDB Metabolites of Enzymes	1.0	null
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31119
BRD-K24292260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2819
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01191
benzathine benzylpenicillin-4022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26926
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824327
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97401
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
ERA-27197147-CHIP-SEQ-ENDOMETRIOID-ADENOCARCINOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51168
lisuride-5028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fulvestrant-6925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39573
inner CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23144
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20666
hsa-miR-4651	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_HSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885026
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47444
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
guanyl-nucleotide exchange factor activity	GO Molecular Function Annotations 2023	1.0	null
fosfosal-4239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.869652
BABAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05347
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03506
AU565	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tamoxifen-375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38946
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68515
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916736
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63988
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064775
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.62422
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01087
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04487
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4441	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.40994
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11584
ethaverine-6737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU81	CCLE Cell Line Gene Expression Profiles	1.0	1.76597
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.62187
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997071
guanethidine-3171	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
NT5C3B	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8497275-41388_2021_1985_MOESM9_ESM.xlsx-ER_targets_ER-SRC3-RAC1_sites-Nearest_Ensembl_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
econazole-7305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K90852412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5633
isotretinoin-7438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00005
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BICR31	CCLE Cell Line Gene Expression Profiles	1.0	1.86551
tanespimycin-6985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96314
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60198
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04592
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04978
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844616
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11167
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HS766T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56641
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gfi1b_OE_GDS4302_425_mouse_AMuLV (pro-B Abelson leukemia virus transformed) cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-A08363225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06721
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7275
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-30c-5p	MiRTarBase microRNA Targets	1.0	null
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41472
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
benperidol-2475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68083867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0197
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DANG	DepMap CRISPR Gene Dependency	1.0	3.36157
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trifluoperazine-910	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hecogenin-7175	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
digoxin-6724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08017
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
fulvestrant-1663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.59781
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75409
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49268
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00005
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00289
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27476515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82689
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12555
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPM-0726-SM-3LK7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46777
BRD-K13076765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28811
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34106082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39893
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
erythromycin-6729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57336
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.854542
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18044
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979461
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09345
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68092
SUZ12	ChEA Transcription Factor Targets	1.0	null
ebselen-3458	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K18519621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08669
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9221
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57218
DK-MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57642
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
3-acetylcoumarin-3044	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01244
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14134
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939912
BRD-K63761383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1631
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845186
ACER3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01246
BRD-K57359365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25982
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63410075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15862
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09102
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68712
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00881
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858424
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23919
cefoxitin-2735	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.8655
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40849
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161846,GSE161849_3_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amiloride-3990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1763
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1967
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal dominant nonsyndromic deafness 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.015
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914173
ATM_KD_GSE54268_661_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NDFIP2	Pathway Commons Protein-Protein Interactions	1.0	null
MLXIP_01_03	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59572
celecoxib-206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0483
Weight Loss	CTD Gene-Disease Associations	1.0	1.08655
isotretinoin-6017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
pyrimethamine-4194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14378
SERPINF1	Pathway Commons Protein-Protein Interactions	1.0	null
testosterone-4676	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K24554824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10157
fusidic acid-6754	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53076
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62101
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34999
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3837
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.991416
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dantrolene-4343	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36686
CUBN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00469725
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW684	GDSC Cell Line Gene Expression Profiles	-1.0	-2.84238
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	5.17446
MCF7_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158449
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00223
TMSB4X	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K59006776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09418
PMC9883165-41375_2022_1744_MOESM3_ESM.xlsx-RNA-Seq_of_CEBPA_specific_genes-RNA-Seq_analysis_of_genes_associated_with_a_DHS_that_has_a_CEBPAx2_specific_Hi-C_interaction_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29193
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
pizotifen-3134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18691
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4319	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prestwick-692-2165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.684
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939037
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8569
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16588
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988861
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920511
BRD-K04544693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02953
BRD-K98537764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00034
BRD-K47716724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28345
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38338
positive regulation of GTPase activity	GO Biological Process Annotations 2023	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.880011
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-0926-SM-3TW8L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850112
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44622
fulvestrant-1076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70207
HGC-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66764
NELFE	ENCODE Transcription Factor Targets	1.0	null
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955371
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053066
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17008
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.891971
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03918
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.80257
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1078-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_16629_KO_Kir4.1_SRP133512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.94767
Prestwick-689-7173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88484
BRD-K55793776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66807
MAPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058634
CRCGN017_MCF10A.WT.HP_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43675
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00623
Perturb_7991_KO_Dnmt3a_ERP107945	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84071
BRD-K17559923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04418
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96239538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68679
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8245
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173411
15831674-Table1	GeneSigDB Published Gene Signatures	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41906
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K19817946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1417
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-520d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.06406
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6231
EMILIN complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6001
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43109
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65938
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.963207
PMC6345883-41598_2018_37397_MOESM10_ESM.xlsx-AR_D0_VS_D14__TRANS-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51970157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89709
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05013
NCIH1184	CCLE Cell Line Gene CNV Profiles	1.0	1.3739
geldanamycin-972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17085
BRD-K10541973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29263
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12508
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989294
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24842
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-106b	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
trihexyphenidyl-4133	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K45893504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16825
alpha-estradiol-403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60701773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06554
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15485
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10973
Prestwick-864-3994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K96596828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07383
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09494
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8391-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7794-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
meprylcaine-6204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.863262
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5623
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sirolimus-6981	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44851
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
small GTPase mediated signal transduction	GO Biological Process Annotations 2023	1.0	null
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.949496
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.753
Lung adenocarcinoma_LUAD_TCGA-78-7152-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29339
D425	DepMap CRISPR Gene Dependency	1.0	2.78867
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.61427
fulvestrant-5202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:C05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07071
TIMM23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01527
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51886
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916838
BRD-K99581286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25355
BRD-K24525269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14402
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76588894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12373
EOMES-21245162-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K12930517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58442
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
azacitidine-4128	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8525
BRD-K08260539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22222
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866843
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02371763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23763
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44015
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982535
GSE236497,GSE236500_1_v_0_pemrametostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pentamidine-639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tetramisole-2489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
eucatropine-3416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.949581
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841277
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853359
GTEX-XV7Q-0626-SM-4BRV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83562
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-8170-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0667
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57231
hsa-miR-3074-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K36me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_U87MG_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4971
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H376	DepMap CRISPR Gene Dependency	1.0	2.24414
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Cardiomyopathy_Myocardial tissue_GSE1869	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66063
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00818
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837481
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
dapsone-5078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52123140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03558
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848135
BRD-K15201964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05477
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02436
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904563
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3124-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-20b	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
DPF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00461928
BICR22	CCLE Cell Line Gene Expression Profiles	1.0	2.21774
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.82543
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13236
suxibuzone-2503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QK-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR2	ChEA Transcription Factor Targets	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7444
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02967
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22993
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06830450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57566
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27245
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	0.88894
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939015
Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.879703
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03661
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DSH1	GDSC Cell Line Gene Expression Profiles	1.0	1.64837
Monocyte percentage of white cells	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.969897
hsa-miR-3115	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Phosphatidylinositol 3-kinase complex, class IB	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2836
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62577212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33943
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06388
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.817962
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11297914-41389_2024_531_MOESM1_ESM.pdf-129-HIVEP2_HIVEP2	Rummagene Transcription Factor Associations 2026	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3593
ChIP_NANOG_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835079
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5009
H1_Derived_Mesenchymal_Stem_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.984768
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30876
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44909
H3118	DepMap CRISPR Gene Dependency	1.0	3.93556
metformin-3	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27591
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842477
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
saquinavir-3549	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36496
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6668
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70921
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-MY-Z	GDSC Cell Line Gene Expression Profiles	-1.0	-1.79809
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85476
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33802
CRCGN017_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64675
clonidine-4478	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
furazolidone-4098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55742134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60628
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864899
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
15-delta prostaglandin J2-1011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESR1-20079471-T-47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE143743_0_v_2_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9298
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00527
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gfi1b_22201127_amulv_gof_mouse_gpl6246_gds4302	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.010486
GSE166004_3_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81456
Rectum adenocarcinoma_READ_TCGA-F5-6864-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	0.952466
fulvestrant-7490	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23316
CRCGN014_HEPG2_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06684
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10364
MFE296	DepMap CRISPR Gene Dependency	1.0	2.42854
Benign meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83614
ioversol-6726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17664
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21601
ESO26	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12624
sirolimus-1646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IST-SL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells -  7 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.843533
hsa-miR-636	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09258
CCNT2	ENCODE Transcription Factor Targets	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856011
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1591
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22299
hsa-miR-1273e	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05966
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCUBM	DepMap CRISPR Gene Dependency	1.0	4.98593
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039786
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
isoxsuprine-4205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8055
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07714
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39559
BRD-K31757099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4718
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00381
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44502
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19664
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835667
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79596
BRD-K53901855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65028
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.931678
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5909
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980095
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47Y-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
dexibuprofen-6712	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03198
CUTA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE129772_2_v_1_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-373	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33679
hsa-miR-4763-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABHD16A	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952863
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K60918542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24798
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.13334
Perturb_7485_OE_Mir489_SRP155560	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.22943
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal immune system physiology	MPO Gene-Phenotype Associations	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16031
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175631
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9916
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22079
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5911
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6691
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941184
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66291
valproic acid-348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0087
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K77144444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23363
levomepromazine-3701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2166
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Guanosine diphosphate	HMDB Metabolites of Enzymes	1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12085
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16118
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17778
PMC11373733-ABR-13-34_Suppl1.pdf-322-PDX1_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
orciprenaline-4248	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74399971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67865
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62663
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fulvestrant-5926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43573
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04177
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16123
emetine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00707
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12591
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54803
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53814
BICR56	CCLE Cell Line Gene Expression Profiles	1.0	1.54969
hsa-miR-873	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4994
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02967
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29875
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33711
indoprofen-4249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3291
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892221
GTEX-OXRN-0226-SM-2I5EJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23189
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chlormezanone-4636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16192
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3527
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32760954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64083
metrizamide-4075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68875
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03968
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36492
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5234
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96451
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971487
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48069
BRD-K32439647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03982
MN-9D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.025
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978565
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42455540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8522
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3439
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94606
GSE244710_3_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23718
TT	CCLE Cell Line Gene Expression Profiles	1.0	2.2276
GSE109530,GSE109531_2_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8794
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.58721
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22025
organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08847
EOMES	ChEA Transcription Factor Targets	1.0	null
GTEX-WH7G-1526-SM-4LVMX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997911
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21564
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888033
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27914
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2848
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35823
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30572
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12152
pivampicillin-5465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3397
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16699
azathioprine-5627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_4431_KO_Tnfrsf1b_SRP052924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.18344
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1299
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894439
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
trimipramine-3004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45868
NCI-H716	COSMIC Cell Line Gene Mutation Profiles	1.0	null
flucloxacillin-5527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25547
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75277
BRD-K08436070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30836
hsa-miR-320b	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31706
BRD-K51522005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05942
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16697
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34606
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87494
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25026
CFPAC1	DepMap CRISPR Gene Dependency	1.0	3.51176
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966762
tioguanine-642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dihydroergotamine-4502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7581777-41419_2020_3029_MOESM6_ESM.xlsx-MNX1_ChIP-Symbol_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC22A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00451526
GSE210885_2_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09028
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.983073
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77603
ATAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34032
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01102
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03709
BRD-K04441230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2888
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU324	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63174
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43832
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880649
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
metronidazole-4023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28265
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83039
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6847
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.98287
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09177
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24424
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26945
BRD-K74811560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45865
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971487
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19881
PAX5	ENCODE Transcription Factor Targets	1.0	null
MCF7_KW-2449_10µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.010559
GSE111247_0_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52285
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825373
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
methylbenzethonium chloride-2190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pyrvinium-3518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH1563	CCLE Cell Line Gene CNV Profiles	1.0	1.81983
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.60855
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997873
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24308
KDM4A	ENCODE Transcription Factor Targets	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11539
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1681
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	1.0	1.0751
APRT	Pathway Commons Protein-Protein Interactions	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23097
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81214
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58643
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZB-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11542230-12985_2024_2548_MOESM4_ESM.xlsx-MR_results-exposure_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918069
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04177
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83463
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tachycardia_Myocardial tissue_GSE7999	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.59152
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851986
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5369
5213008-898	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Disorders of Sex Development	CTD Gene-Disease Associations	1.0	1.01437
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15293
dexamethasone-374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13045_KO_Tmem259_SRP195618	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.79993
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03074
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
LS513	DepMap CRISPR Gene Dependency	1.0	2.96507
hsa-miR-17	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
BRD-K51707293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83026
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25765
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.994803
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827652
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1693	COSMIC Cell Line Gene CNV Profiles	1.0	2.36889
regulation of GTPase activity	GO Biological Process Annotations 2023	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K40558736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38212
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.6193
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895248
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.718083
nifuroxazide-4253	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64572
hsa-miR-3124-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80744
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.7019
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38338
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951265
BACH1	ChEA Transcription Factor Targets	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.890476
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38746
CRCGN017_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4225
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0003
MCF7_Belinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131281
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28279
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1260	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8386
BRD-K95479169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77006
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85051145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15324
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56072
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
vancomycin-2498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.983202
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76266
pre-B cell receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
valproic acid-347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34700473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09176
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6355
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50658
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7399
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05089
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2951
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
monorden-6938	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47997
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11716045-peerj-13-18816-s007.xlsx-Sheet1-KLF9_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mouth	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8656
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-29b	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
OE21	DepMap CRISPR Gene Dependency	1.0	3.10318
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cefotetan-3997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37399
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22869
MCF7_UNC0631_1µM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125772
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73709
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67491
BRD-K77908580_entinostat_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89636
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9009
naproxen-2533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12792
sparteine-2134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.791
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13233
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03794
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.07755
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.921983
hsa-miR-376a	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
BRD-K90562751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25016
PMS2	Pathway Commons Protein-Protein Interactions	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10095
BICR31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78896
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33423
PAPSS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549874
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35715
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23219
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12516
integument	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2951
Perturb_17431_KO_Tcf7_SRP096345	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07582
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5836
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.968532
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2505
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERBB3_knockdown_65_GSE19921	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.81362
TPRG1L	Pathway Commons Protein-Protein Interactions	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.0439
Familial nephrotic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966107
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1235
PK1	CCLE Cell Line Gene CNV Profiles	1.0	1.5051
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	1.41877
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52238
Mitochondrial creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EVSAT	DepMap CRISPR Gene Dependency	1.0	2.4668
BRD-K06550516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55989
BRD-K62707745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02753
aminophylline-3374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
epitiostanol-4204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09037
BRD-K70361311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34724
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934264
Lung adenocarcinoma_LUAD_TCGA-69-8453-01A-12R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH508	CCLE Cell Line Gene Expression Profiles	1.0	1.62425
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12955049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19299
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24455
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4164
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60324
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.875
cefotiam-6762	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01683
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0997
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.997947
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24842
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970628
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11985
tretinoin-3165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MLH1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6578
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92934