association	dataset	threshold value	standardized value
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHHCALL2	CCLE Cell Line Gene Expression Profiles	1.0	1.79971
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87481
HIVEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3356
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2878
CCNT2	ENCODE Transcription Factor Targets	1.0	null
BICR16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63025
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
17178894-Table2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19155
Brain Lower Grade Glioma_LGG_TCGA-HT-7481-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67723
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866687
Gbm cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924346
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.69551
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.50807
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97898
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21259
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_6_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3451
icSARS-Cov_Day7_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04071
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01427
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.03667
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01244
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.35773
Adrenomedullin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.377745
Sm-like protein family complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.382
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.37188
S0-EE-XMXE_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213974
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16871
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30838
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04537
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06602
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleoplasm part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14394
GTEx BloodVessel 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	13.7572
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.89028
GSE147366_3_v_5_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910149
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910037
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06876
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09991
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
poly-pyrimidine tract binding	GO Molecular Function Annotations 2025	1.0	null
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18484
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63553
RBM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9902
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07333
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1547
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98008
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06804
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6499-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246660_1_v_0_lmo3_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904307
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932832
HEC-1-A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1248
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96984
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269097
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-KDM5B-Unnamed_6_KDM5B	Rummagene Transcription Factor Associations 2026	1.0	null
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.903272
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862835
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18563
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67824
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837065
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18645
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7872-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11589140-41416_2024_2881_MOESM1_ESM.pdf-422-RAG1_RAG1	Rummagene Transcription Factor Associations 2026	1.0	null
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03873
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33383
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893304
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59137
mRNA cleavage and polyadenylation specificity factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86051
nucleoplasm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240636
NCI-H1792	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.508846
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19595
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51787
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055755
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85621
VMCUB1	CCLE Cell Line Gene Expression Profiles	1.0	1.3483
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.63108
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08476
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04189
regulation of mrna splicing, via spliceosome	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979415
CALU-6	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042094
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04854
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.067275
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843596
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03114
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE138939_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994589
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03433
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06314
Lung squamous cell carcinoma_LUSC_TCGA-18-3411-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852859
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52666
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.8076
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
cellular_component	GO Cellular Component Annotations 2015	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1775
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25521
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.91819
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991672
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.31698
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950157
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12271
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29588
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09472
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50525
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEx Uterus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.90192
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4619
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54688
GTEx Uterus 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	20.0668
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41A-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6877
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8086
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924068
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852393
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977107
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08055
HMGN3	ENCODE Transcription Factor Targets	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36583
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19618
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82359
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
P4HB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12555
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051289
Brain Lower Grade Glioma_LGG_TCGA-P5-A730-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
22RV1	CCLE Cell Line Gene Expression Profiles	1.0	1.47592
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8501
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08209
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1886
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1281
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980217
tamoxifen_homo sapiens_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16025
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368611
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.855899
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11114
Venom gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	3.46748
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41209
U251MG	DepMap CRISPR Gene Dependency	1.0	4.98356
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05207
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12186
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6023-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11681
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54477
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19025
NCIH1155	CCLE Cell Line Gene Expression Profiles	1.0	1.52338
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.7256
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-370-BNC2_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Glioma stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61266
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Regulation of gene expression and protein modification	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
nt2d1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95899
PATU8988S	CCLE Cell Line Gene CNV Profiles	1.0	1.75311
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33003
PMC3371315-NIHMS350140-supplement-10.xls-MCF7-T47D-SK-453_Down_SK-453_xl-Supplementary_Table_3_ER-negative_FOXA1_signature_Genes_decreased_only_in_MB-453_and_SKBR3_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22255
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59502
hsa-miR-1264	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96815
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16035
cellular response to stress	GO Biological Process Annotations 2015	1.0	null
SRSF7_02_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5911
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2987
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887252
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14563
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57879
RHOXF2	Pathway Commons Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.929953
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1117
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.357965
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859547
Prostate adenocarcinoma_PRAD_TCGA-HC-7080-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00279
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.990994
TAF1	ENCODE Transcription Factor Targets	1.0	null
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32057
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39517
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Endolysosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51208
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0269
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apoptotic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38458
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948008
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825945
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75913
cellular response to chemical stimulus	GO Biological Process Annotations 2015	1.0	null
GSE96777,GSE96778_3_v_2_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_11_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887641
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41739
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86427
NUGC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13913
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41739
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38502
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.14352
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51793
LPS510	DepMap CRISPR Gene Dependency	1.0	9.88625
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25381
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49971
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23539
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14011
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05926
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15626
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25014
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.554117
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58964
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84037
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3544
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853697
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovarian serous carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.408676
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228066
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994164
SARS-BatSRBD_96Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.57229
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46329
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4543
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941981
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25106
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27923
EEF1AKMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03445
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835279
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22887
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00629
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02147
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12369
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	1.67301
ARX_KO_GSE12609_3_mouse_brain (subpallium, Pou3f-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	5.38304
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
diencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TMUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.76253
hsa-miR-4793-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0386
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72136
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870689
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15096
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07767
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996938
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01487
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04503
MYC	ENCODE Transcription Factor Targets	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2122	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39732
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.85981
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1016
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49908
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0911
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	4.83347
MAX	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835177
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rna splicing	GO Biological Process Annotations 2015	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.542
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15935
hsa-miR-4796-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77411
r1 part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05315
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6233
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36634
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18032
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16581_KO_Cited2_SRP321006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.61659
AR_01_278	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.04906
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31942
nuclear speck	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_4_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLK1_druginhibition_181_GSE46856	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.64177
RT-112 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42461
increased eosinophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994747
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00665
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.75959
BEL-7404 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.918868
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATP5ME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23535
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49397
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06544
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1023
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853345
brain	GTEx Tissue Gene Expression Profiles	1.0	0.871399
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9591
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2126	CCLE Cell Line Gene CNV Profiles	1.0	1.7559
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.030962
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15675
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07544
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NUP205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30329
OE21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68806
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8875
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94149
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269657
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1386
TE11	CCLE Cell Line Gene CNV Profiles	1.0	2.53874
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45683
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.868892
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34733
NCIH1693	CCLE Cell Line Gene Expression Profiles	1.0	1.6545
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41809
hsa-miR-3164	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
HCFC1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4658	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BMI1	ChEA Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.849
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861912
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838428
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07803
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24591
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01124
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.608
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
a549	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
Lung squamous cell carcinoma_LUSC_TCGA-66-2769-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945966
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890238
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10367
Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856232
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9571
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63927
EW1	DepMap CRISPR Gene Dependency	1.0	7.39113
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41112
NCI-H1688	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78962
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2798_KD_TRPS1_SRP125141	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.931
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3022
19139136-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989208
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04035
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210665
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01699
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76845
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994933
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920826
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02554
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VM-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-LA-A446-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-2.06108
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904565
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09123
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976622
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.04944
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270909
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.9726
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62018
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61102
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
response to oxidative stress	GO Biological Process Annotations 2015	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2627
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5785
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.104759
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936964
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0842
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.00182
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33859
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66863
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919744
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0134
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857896
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15623
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
16207381-Table1Sb	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33711
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.78118
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.442394
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00842
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nuclear body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.437356
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24708
Lung adenocarcinoma_LUAD_TCGA-55-8207-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.951718
Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13656
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28038
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25521
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
u937	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.24206
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25491
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23847
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BV-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.046
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959037
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8732
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.958193
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12512
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25074
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95815
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2744
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29531
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
EPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82924
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10018
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07385
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-583	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
single-stranded rna binding	GO Molecular Function Annotations 2015	1.0	null
RPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.645
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938269
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19654
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40829
Nuclear stress granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.559
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79992
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99064
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.978893
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42361
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875136
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49732
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334537
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1568
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3173
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
regulation of mRNA splicing, via spliceosome	GO Biological Process Annotations 2023	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83663
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901032
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28779
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0056
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	1.90945
protein homodimerization activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2841
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.894404
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82439
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72678
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55952
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3269
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94019
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958616
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44155
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941823
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04015
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4999
nucleoplasm part	GO Cellular Component Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
PHGDH_KO_GDS2874_125_mouse_embryonic head tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nuclear speck	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74997
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89921
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829905
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983933
rectum	HPA Tissue Protein Expression Profiles	1.0	0.934519
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.454
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07084
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12517
NCIH1694	CCLE Cell Line Gene CNV Profiles	1.0	1.71559
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01095
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63996
SARS-CoV NSP16_Day4_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.5482
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55452
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57841
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43969
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11656
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06342
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
RPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43839
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48164
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09379
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3120-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918487
H3K27me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LYN	Pathway Commons Protein-Protein Interactions	1.0	null
cellular response to oxidative stress	GO Biological Process Annotations 2023	1.0	null
Ewing's sarcoma family tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
recurrent viral infections	GWASdb SNP-Phenotype Associations	1.0	0.590838
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30187
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20189
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03079
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99734
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42955
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4048
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33253
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77143
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_7Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.24363
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4344
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0622
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1487
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.833111
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00296
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04351
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846618
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FL-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944114
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B8-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
FGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16504
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66582
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24548
cellular response to oxidative stress	GO Biological Process Annotations 2015	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6451
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947224
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HQ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17536
Autosomal recessive nonsyndromic deafness 77	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.691426
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23216
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.68451
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.10646
TALL1	CCLE Cell Line Gene CNV Profiles	1.0	2.04953
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03141
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E0-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49557
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993146
Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855354
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4531
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878549
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983719
Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24961
hsa-miR-640	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01529
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949145
Lung squamous cell carcinoma_LUSC_TCGA-18-4086-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67221
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967086
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6948
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881535
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41269
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92475
Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34165
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55836
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07094
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30469
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65685
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92475
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994654
ARH77	DepMap CRISPR Gene Dependency	1.0	5.42156
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17646
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58844
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
single-stranded RNA binding	GO Molecular Function Annotations 2025	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.970422
U1 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.412
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.997011
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
Nuclear exosome targeting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.151
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38003
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
TDOTT	DepMap CRISPR Gene Dependency	1.0	7.55459
cellular response to chemical stress	GO Biological Process Annotations 2023	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38458
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12423
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44782
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975036
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59283
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40858
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43317
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874193
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09273
hsa-miR-556-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05625
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07088
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79042
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0548
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832101
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50313
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866962
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00979
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YX-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1399
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52257
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNA recognition motif domain	InterPro Predicted Protein Domain Annotations	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14838
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5556
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.0446
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881556
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20174
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311437
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15035
H3K4me1_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01929
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87006
ovary	HPA Tissue Gene Expression Profiles	1.0	1.54589
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870782
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57499
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.929306
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.10401
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25938
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06978
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20694
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38161
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74504
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68051
PMC10260402-41588_2023_1399_MOESM4_ESM.xlsx-G_STAT3_x_T21_RNAseq_HSA21-Gene_name_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890519
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63408
PU.1_KD_GDS2411_175_mouse_Preleukemic hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE131649_4_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37056
FIH_Deficiency_GDS3769_511_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.593733
hypothalamus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.639
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09685
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8763317-MO-018-D1MO00236H-s002.xlsx-PHF21A_S0_1-Gene_names_PHF21A	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05883
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
OXSM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65849
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01661
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5656
PMC6441234__F1	PFOCR Pathway Figure Associations 2023	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0854
developmental process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-2053	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18512
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1256
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904565
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26153
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34141
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
F36P	CCLE Cell Line Gene CNV Profiles	1.0	2.69435
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39593
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-146a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NSUN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12914
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BMPR1A_knockout_222_GSE48092	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29543
TYW3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89997
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pontine reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.832453
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_5_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.969916
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868218
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ewing's family tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04268
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943885
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.939484
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78477
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1281
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62445
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of OCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0267
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49539
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16681
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.95822
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6297
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868784
poly(U) RNA binding	GO Molecular Function Annotations 2023	1.0	null
RCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06661
Lung adenocarcinoma_LUAD_TCGA-64-1680-01A-02R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
placenta	HPA Tissue Protein Expression Profiles	1.0	0.934519
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02866
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845541
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.863855
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.04733
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66241
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91804
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08521
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892142
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
gigantocellular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22002
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28666
HDAC2	ENCODE Transcription Factor Targets	1.0	null
regulation of mrna processing	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LTBR_INHIBITION - 3 Days_GDS2005_730_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935198
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.941
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870689
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39084
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13248
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BPH1	DepMap CRISPR Gene Dependency	1.0	2.88525
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3237
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92335
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6683
ZEB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845401
poly(u) rna binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31064
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926838
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00567
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19903
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01942
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4407
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.61052
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89157
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98021
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79814
TE5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60318
u87	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33274
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-656	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18559
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.994164
H3K4me1_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91477
PMC9314667-Table_1.xlsx-Regulons-TFAP2A_TFAP2A	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80287
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22959
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.80388
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05738
A375	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50992
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01332
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H1-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0397
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.125
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
C3A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.02924
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47089
BEN	CCLE Cell Line Gene CNV Profiles	1.0	1.69965
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962071
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36636
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059213
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00309
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19682
Perturb_13180_Mut_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.76183
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3936	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999597
nucleus	GO Cellular Component Annotations 2025	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.955677
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
PCI30	DepMap CRISPR Gene Dependency	1.0	2.94792
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.386941
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919743
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10919
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
hsa-miR-135a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24884
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-633	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0466
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.828112
disease	GWASdb SNP-Disease Associations	1.0	0.028575
Lung adenocarcinoma_LUAD_TCGA-55-A48Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.49834
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06561
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04152
ACYP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20052
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29124
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35096
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04899
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08478
SOD2_KO_GDS1080_128_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.48145
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31652
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08009
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08224
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35748
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10064
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.279204
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2441
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1281
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.986367
PMC8755441-mmc3.xlsx-IRF7-Up-IRF7Del246-647_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06805
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864023
Epithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50813
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02615
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01321
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840859
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133516_0_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
CDK2_knockdown_132_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.46709
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
hsa-miR-487a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
brain disease	GWASdb SNP-Disease Associations	1.0	0.158521
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17084
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17425
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12912
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54665
HDAC3_KO_GDS4886_29_mouse_heart - 6 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NTRK3_drugactivation_67_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.800142
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891698
GSE142210_4_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91156
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921091
DA-35-DU85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.592743
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1789
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36405
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15465
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27182
REST	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988706
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
vorinostat_homo sapiens_gpl6947_gse41504	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12302463-12935_2025_3917_MOESM6_ESM.xls-MR-5086-MR_analysis_results_of_ieu-b-5086_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15746
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEL	CCLE Cell Line Gene Expression Profiles	1.0	1.36788
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.215
HS766T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44503
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.766919
occipital cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0267
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	2.21251
LTBR_INHIBITION - 27 Day_GDS2005_731_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50601
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29011
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4242
OB-65-AI50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.24833
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11815
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TC71	CCLE Cell Line Gene Expression Profiles	1.0	1.90628
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0541
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.927263
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61755
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955906
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08799
GBM-8401 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23165
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10472
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
mantle zone of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0258
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878165
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18796
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stereocilium tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01153
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.034413
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.934519
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76845
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901772
Small nuclear ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39989
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86301
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02563
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15462
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.960493
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946486
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17574
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12958
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08454
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47107
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
LTBR_INHIBITION - 35 Day_GDS2005_732_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041539
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16795
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.54886
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	2.74674
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.907702
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QD-01A-32R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Perturb_16734_KO_Tnfrsf11a_SRP103818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.98838
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31169
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944251
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19361
exon-exon junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	0.956064
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03694
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17673
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20698
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.86752
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17013
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-621	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22634
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.89309
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5715
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980918
HEL9217	CCLE Cell Line Gene Expression Profiles	1.0	1.55643
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.1808
testis	HPA Tissue Protein Expression Profiles	1.0	0.934519
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61284
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82167
neuropeptide-S nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43854
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54739
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49357
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06703
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55111
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30005
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906898
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
intermediate gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24892
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08355
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32868
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.573
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13948
Olfactory tubercle, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15408
suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.058681
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01765
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18798
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44571
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
response to chemical	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21822
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79452
BEN	CCLE Cell Line Gene Expression Profiles	1.0	1.69845
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	2.92081
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC9A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05086
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872702
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0809
SARS-CoV_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78406
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267591
RBMX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40668
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87612
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4401
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
LN443	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64283
Diencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-140-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
valproic acid_homo sapiens_gpl6244_gse23909	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37637
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.83714
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38422
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442962
RT112	CCLE Cell Line Gene CNV Profiles	1.0	1.42352
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27602
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44035
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77481
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12363
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28329
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.19829
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.183541
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1753
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05734
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular response to chemical stress	GO Biological Process Annotations 2025	1.0	null
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08832
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53051
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74496
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MF-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51844
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93175
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12696
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02147
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859961
ZFX_KO_GDS2718_151_mouse_hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860501
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SP-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2644
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00184
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.32635
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21188
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0647
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3746
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19805
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00144
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45179
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.33668
HCC1954	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45956
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19903
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_4_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47628
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23857
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31318
ZNF385C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14723
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40724
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58634
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990436
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05195
NCIH2106	CCLE Cell Line Gene CNV Profiles	1.0	1.4333
Rhabdomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6246
Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20387
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
DHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37424
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02264
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXO27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.179
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09876
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.63638
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.47189
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20116
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
recurrent infections	GWASdb SNP-Phenotype Associations	1.0	0.29441
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09817
nuclear part	GO Cellular Component Annotations 2015	1.0	null
PDXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57125
JUND	ENCODE Transcription Factor Targets	1.0	null
CALU6	CCLE Cell Line Gene CNV Profiles	-1.0	-3.19293
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
rna binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3813
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F0-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.60913
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876725
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904565
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-CA-04-2009(H1N1)_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.90136
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05527
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.75453
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.899737
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09226
Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47105
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22985
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991672
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0249
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15382
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.980453
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3140-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
mrna processing	GO Biological Process Annotations 2015	1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
nuclear speck	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.782326
Perturb_542_OE_EWSFLI_SRP168621	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.457749
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6293
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.38105
NCIH1666	CCLE Cell Line Gene CNV Profiles	1.0	1.41312
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1748
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25886
colliculus superior	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78477
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268939
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.387098
mRNA_SOX2_17515932	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34762
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979995
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.4024
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21025
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85066
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1473
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKRC20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66636
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16829_KO_Ras/Apc_SRP306767	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.05867
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45746
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16657
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45987
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07109
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05843
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.031011
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44698
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19833
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207108
Complete Trisomy 21 Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1428	CCLE Cell Line Gene Expression Profiles	1.0	1.53257
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.04487
response to stress	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59098
SNU423	DepMap CRISPR Gene Dependency	1.0	2.17322
Perturb_8633_KO_Sh3gl1/Sh3gl2_SRP082219	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.83498
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H196	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282343
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31593
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983329
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXD9_01_70	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.47071
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35914
H3K9me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2055
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00955
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.874109
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50562
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71162
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874122
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.944463
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947659
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20928
KYAE1	DepMap CRISPR Gene Dependency	1.0	11.248
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34459
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36787
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05615
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial gray layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.8451
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13555
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16854
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ewing's sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.312
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.046
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04222
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919819
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.841324
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01471
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907813
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03261
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40445
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94996
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0525
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.068
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00698
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826777
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043394
HDAC3_KO_GDS4886_66_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861218
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15644
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12206
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18171
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880612
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192362_1_v_0_erastin_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18796
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
single-stranded RNA binding	GO Molecular Function Annotations 2023	1.0	null
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52666
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37944
Spliceosomal tri-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
E4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43669
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.849073
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24404
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60998
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03624
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824546
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4971
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Spliceosomal snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.494
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2848
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.902756
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A705-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10073
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45797
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11479675-NIHMS2019542-supplement-5.xlsx-B_HIF1A_score_vs_chr21-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32519
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.969089
WM88	CCLE Cell Line Gene CNV Profiles	1.0	1.50367
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18346
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDAMB435S	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75312
Perturb_540_OE_EWS/FLI_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.18058
SKNMC	CCLE Cell Line Gene Expression Profiles	1.0	1.84966
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892219
endometrium_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.927759
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
MAZ	ENCODE Transcription Factor Targets	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946486
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42224
BE2-M17	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909599
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31524
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33161
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38656
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23455
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1143
rna processing	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-18-GQ83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.349005
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3119	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05668
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14859
Spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.78
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60219
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46089
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.986684
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873469
TET2_KO_GDS4287_431_mouse_GMP - bone marrow progenitor population	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4435
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11985
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_14-Supplementary_Table_14_ETV6-activated_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30057
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91999
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896815
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2214
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11976
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
CTCF	ENCODE Transcription Factor Targets	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.49124
GSE213588_9_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2385
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888122
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26857
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.934519
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00852
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861218
TMCO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60371
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.945889
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46706
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22208
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.209546
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1256
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906262
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868071
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1335
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11201
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24788
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.969057
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52846
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1598
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844447
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2377
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08894
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8391-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4703-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53793
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0667
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4412
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16416
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_541_OE_EWS/FLI_SRP168620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.56686
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2926
hsa-miR-3659	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0347
layer 2 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60818
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943509
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59584
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15643
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02904
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1662
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.04376
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872708
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.966001
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.91494
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19034
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840859
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15746
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00804
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0922
hsa-miR-3185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54F-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24928
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918299
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1843
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.825799
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0111
Enterovirus 71_8Hour_None_GSE15323	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.2422
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867432
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977436
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74303
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7333
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.878333
KDM4A	ENCODE Transcription Factor Targets	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78177
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26277
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25421
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930663
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825945
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259738
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185872_0_v_1_methotrexate_human	RummaGEO Drug Perturbation Signatures	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.298
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06123
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22399
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51519
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3995
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69741
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72082
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61497
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11201
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCE4	DepMap CRISPR Gene Dependency	1.0	6.98538
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15644
H3K27me3_iPS-15b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEx Ovary 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	10.5463
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PATU8988T	CCLE Cell Line Gene CNV Profiles	1.0	1.67951
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
Neuroepithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
nucleoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21681
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06187
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cell part	GO Cellular Component Annotations 2015	1.0	null
MZ1-PC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8188
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2267
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	1.52655
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00065
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95242
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27436
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5909
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05133
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of alternative mrna splicing, via spliceosome	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5555
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44865
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.205575
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64842
C2CD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05427
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.995914
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94087
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1138
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3124-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34733
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18045
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59415
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0992
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
DDX39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2289
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A896-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65188
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895184
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12503_KD_ESR1_ERP130561	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.58027
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828443
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.215
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08751
regulation of mRNA splicing, via spliceosome	GO Biological Process Annotations 2025	1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7749
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.85482
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07473
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917511
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49781
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13414
nuclear body	GO Cellular Component Annotations 2015	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10675
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33162
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10431
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0065
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.34955
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855546
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34519
SKES1	CCLE Cell Line Gene Expression Profiles	1.0	2.53008
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08762
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71122
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17122
Perturb_13186_Mut_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8216-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0686
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73Q-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44O-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11956
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11224
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95866
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2871
RDES	CCLE Cell Line Gene Expression Profiles	1.0	2.45144
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27386
SNU-475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870299
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
E2F1-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04206
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864023
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.324095
Sarcoma_SARC_TCGA-SG-A6Z7-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2356
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08799
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96023
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126219_0_v_1_haloperidol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44087
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1942
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050182
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54487
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5978-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34389
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49327
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56912
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17601
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52725
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15815
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21141
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202283
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0008-SM-48U2F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04169
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0214
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2514
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00657
GSE120612_4_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97615
response to stimulus	GO Biological Process Annotations 2015	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.945085
PMC5325343-oncotarget-07-63003-s002.xlsx-Supplementary_Table_1-Supplementary_Table_1_Genes_upregulated_by_EWS-FLI1_in_the_Gordon_et_al_data_set_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of rna splicing	GO Biological Process Annotations 2015	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TC-32 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45333
PMC6441234__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976549
down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.780251
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08982
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28603
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC8635809-Table_2.xls-LPS-downregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72059
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12909
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90905
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16393
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.09888
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48282
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	3.62568
MAFK_02_183	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.66253
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99115
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10684
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mrna metabolic process	GO Biological Process Annotations 2015	1.0	null
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3902
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.47379
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spastic ataxia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42742
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13352
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2905
NCI-H2342	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8091-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051145
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15965
Perturb_1341_KD_RAC3_SRP368300	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.61446
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49552
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71037
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.985501
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3200-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Prostate adenocarcinoma_PRAD_TCGA-V1-A8ML-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09537
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MJ-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933754
GSE148692,GSE148695_7_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6417
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.829108
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MHHCALL2	CCLE Cell Line Gene CNV Profiles	1.0	1.37157
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908666
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16305
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262987
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8394-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17536
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54088
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4588
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64476
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	6.6714
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83787
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55377
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19381
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01366
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17972
FAM133B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55176
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07859
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968303
PMC8763317-MO-018-D1MO00236H-s002.xlsx-PHF21A_S0_2-Gene_names_PHF21A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05186
post-spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of mrna metabolic process	GO Biological Process Annotations 2015	1.0	null
MAMLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23621
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21907
A-673 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10105
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86531
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YD8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5535
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GF-81-MU70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263615
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1897
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927959
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CMK	CCLE Cell Line Gene CNV Profiles	1.0	1.61847
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.898733
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
poly-pyrimidine tract binding	GO Molecular Function Annotations 2015	1.0	null
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04305
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81043
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
A-CA-04-2009(H1N1)_12Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.50265
GSE130676_0_v_1_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3994
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21671
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CL-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTEN_01_302	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59893
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06172
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93418
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15003
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.987401
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05017
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.76146
hsa-miR-4795-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249323
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE208350_0_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.966907
nucleoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3316
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.7031
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02584
SARS-ddORF6_72Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69717
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13472
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062457
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07101
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-371-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2399
PMC11297914-41389_2024_531_MOESM1_ESM.pdf-169-E2F8_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01244
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.466076
Prostate adenocarcinoma_PRAD_TCGA-EJ-8470-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01649
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A673	CCLE Cell Line Gene Expression Profiles	1.0	2.21794
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49999
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851873
Asthma_Epithelial Cell_GSE4302	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.63375
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988697
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936627
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.38863
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.934519
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07449
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06696
nucleus of Barrington	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39395
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14329
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06199
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37373
nuclear speck	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30459
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42717
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28917
Posterior parietal association areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24892
Perirenal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11884
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13292
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17536
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86968
GSE147876,GSE147877_4_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57879
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29332
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04113
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02147
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F3-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IB-94-WM88_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212986
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910685
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6417
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET2	CCLE Cell Line Gene Expression Profiles	1.0	1.37722
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17133
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4763
Lung squamous cell carcinoma_LUSC_TCGA-43-A475-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
poly(U) RNA binding	GO Molecular Function Annotations 2025	1.0	null
GSE211262,GSE211263_3_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79465
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845473
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46715
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNA binding	GO Molecular Function Annotations 2023	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04776
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843301
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09123
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981997
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20964
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7502-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
regulation of alternative mRNA splicing, via spliceosome	GO Biological Process Annotations 2023	1.0	null
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05433
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63088
thin ventricular wall	IMPC Knockout Mouse Phenotypes	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_4_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP6R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17179
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33404
BRCA1_DEPLETION_GDS3791_502_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940983
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838905
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16637
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26441
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64388
KMS28BM	CCLE Cell Line Gene CNV Profiles	1.0	2.5245
optic fiber layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95294
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RWDD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33902
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40975
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25396
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6008
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60309
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1102
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3272
ELF1	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830422
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
SK-GT-2	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
SP1	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOK	DepMap CRISPR Gene Dependency	1.0	5.28661
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.327351
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3364
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5195
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2355
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840994
U2 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.183
LUDLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00449
EA-40-KQ08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.353125
E2F1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-603	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Plant cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW8	CCLE Cell Line Gene Expression Profiles	1.0	2.18445
STAT1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06182
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6611
GSE247764_3_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHHES1	CCLE Cell Line Gene Expression Profiles	1.0	3.40789
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837409
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	2.02364
AR_01_323	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.21145
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00772
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38897
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.67457
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2511
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.181
GSE190316,GSE190324_0_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HPAC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64895
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66776
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9203
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32857
PMC12371027-42003_2025_8373_MOESM7_ESM.xlsx-Sheet_1-DYRK3_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Nucleotide-binding alpha-beta plait domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brachydactyly type B2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
NCIH716	DepMap CRISPR Gene Dependency	1.0	2.45269
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.9499
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09729
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0355
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7844-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00279
hsa-miR-365	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3509
LTBR_INHIBITION - 1 Day_GDS2005_728_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01181
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5462
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64067
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949301
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Venom apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
SLC25A46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52181
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62555
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10018
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-2.5954
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66042
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60083
Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2779
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.50846
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10824
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27577
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9563
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25197
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46727
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30729
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205332_1_v_0_queuine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976581
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0693
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.16284
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98089
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.953544
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10229
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31239
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17203
PMC3348545-NIHMS263168-supplement-3.pdf-15-ZGPAT_ZGPAT	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101239_5_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lp1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
SETDB1	ENCODE Transcription Factor Targets	1.0	null
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054254
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041255
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ewing's sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.997008
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057761
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43148
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	2.8683
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.513312
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
mRNA processing(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954376
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74653
testosterone_mus musculus_gpl1261_gse17553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41223
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51983
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00583
SNU-387	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25396
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.880295
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62364
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EZH2	ENCODE Transcription Factor Targets	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.817516
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.20085
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33812
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
hsa-miR-3925-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1144
KLE	DepMap CRISPR Gene Dependency	1.0	3.36182
GSE239844_8_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUDHL10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57852
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44122
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04461
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00455
KC-99-BS89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220606
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01848
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synovial sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.637
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07062
Lung adenocarcinoma_LUAD_TCGA-38-6178-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7668
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133516_5_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04368
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05431
OVKATE	CCLE Cell Line Gene Expression Profiles	1.0	1.51933
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6308
SURF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24453
GSE140284_0_v_1_hhex_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2023	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06312
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21777
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01953
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07545
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887841
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09439
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12777
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.87552
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14403
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.906961
hsa-miR-4280	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
AE-85-LR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206852
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1071-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1_02_181	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61264
KMRC1	DepMap CRISPR Gene Dependency	1.0	3.03499
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904565
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.42457
OC316	CCLE Cell Line Gene Expression Profiles	1.0	1.38608
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3728595-srep02327-s1.pdf-1629-ZNF181_ZNF181	Rummagene Transcription Factor Associations 2026	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
POU5F1	MotifMap Predicted Transcription Factor Targets	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.97615
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879336
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.096465
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08265
Lung adenocarcinoma_LUAD_TCGA-49-4505-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26026
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	1.0	1.48663
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78227
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91731
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13233
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918865
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid_5d	HPA Tissue Sample Gene Expression Profiles	1.0	1.14185
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52173
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	8.17059
VSNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48381
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
16818636-TableS3	GeneSigDB Published Gene Signatures	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54619
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.975675
Lung adenocarcinoma_LUAD_TCGA-95-8039-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24926
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
Cytosolic creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60058
PMC10199266-mmc2.xlsx-RUNX1-DEGs-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
nucleus	GO Cellular Component Annotations 2023	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE181821_1_v_3_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1229
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08946
KCIMOH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45928
TGBC1TKB	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
Hypothalamus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
17724462-TableS2	GeneSigDB Published Gene Signatures	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36935
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.735546
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923619
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16579
hsa-miR-4758-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58537
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB7_01_169	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.7279
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33016
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2025	1.0	null
SARS-BatSRBD_96Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32413
posterior part of anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24617
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48803
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00518
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46K-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3893
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
DAZAP2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1172
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10824
BACH1	ENCODE Transcription Factor Targets	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.68266
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS698T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67965
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841221
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62682
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954751
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867376
HGC27	CCLE Cell Line Gene Expression Profiles	1.0	1.41838
Perturb_11459_KO_Ezh2/Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.0042
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22959
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74389
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37481
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10078
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32878
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01107
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.967156
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26738
SK-N-MC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.998604
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04415
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0062
PMC6347712-pnas.1812449116.sd04.xlsx-Differential_IRF7_to_GFP-ID_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58584
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
E2F1-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
increased basophil cell number	IMPC Knockout Mouse Phenotypes	1.0	null
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29141
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
prion disease	GWASdb SNP-Disease Associations	1.0	0.689083
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34733
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13826
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3336
hsa-miR-103b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6664
NCIH1838	CCLE Cell Line Gene CNV Profiles	1.0	1.32835
CERS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79413
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1998
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.05
KYSE520	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90167
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22983
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08096
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2065
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92475
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30268
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832916
PMC10330983-ab-22-0432-Supplementary-Table-11.pdf-67-RARB_RARB	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2984
KYO1	CCLE Cell Line Gene CNV Profiles	1.0	2.04576
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.17715
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33361
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843897
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15135
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13142
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241438
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06798
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27296
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01394
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
GSE98898_7_v_2_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01416
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.636
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.052807
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36573
LRRC75B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.308
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0103
regulation of alternative mRNA splicing, via spliceosome	GO Biological Process Annotations 2025	1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4458
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04428
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48852
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pancreatic serous cystic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	0.928472
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953351
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
PMC10534007-Table_2.xlsx-S3_unique_up_MSC_V-817_elements_included_exclusively_in_VM-CUB1_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86256
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25714
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1138
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12858
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856361
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14082
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.799892
U4/U6 x U5 tri-snRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Astrocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26264
SHP-77	COSMIC Cell Line Gene CNV Profiles	-1.0	-2.91268
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93202
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.244
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17465
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09982
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.934519
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88955
PMC12508431-44319_2025_552_MOESM1_ESM.xlsx-Table_EV1-Table_EV1_EWS_FLI1_sensitive_gene_targets_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00865
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7906
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25246
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3356
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20926
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IR-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.49541
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06195
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870262
E2F4	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gigantocellular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968059
OSC19	DepMap CRISPR Gene Dependency	1.0	16.1368
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855488
PMC9374162-mmc4.xls-KD_gene_list_heatmap_235_genes-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14344
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41959
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12602
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BY-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.971181
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16354
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913699
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACADVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09014
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43059
MYC-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03491
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
core of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00898
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08029
Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00542
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30322
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE156033_1_v_2_sparc_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57879
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.574994
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36737
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70986
superficial stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99143
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99612
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01966
Hodgkin lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73936
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4IJ-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1092
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
RERFGC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39398
SNRNP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07268
Down Syndrome	DisGeNET Gene-Disease Associations	1.0	null
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57596
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Olfactory tubercle	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00629
TCF3_01_116	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63337
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892123
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.925596
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B_SEnh-Genes_containing_RING1B_EWSR1-FLI1_superenhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.5586
chr21_13979932_A_C_b38	GTEx eQTL 2025	1.0	2.62512
cell differentiation	GO Biological Process Annotations 2015	1.0	null
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7241
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33383
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1065
RFX5	ENCODE Transcription Factor Targets	1.0	null
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19361
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37297
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38096
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920255
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18555
LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
alar plate of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.268
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94034
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93217
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	1.39672
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90789
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38968
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.683765
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1567
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00549
GSE161864,GSE161866_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
VDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04586
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00455
NTRK2_drugactivation_66_GSE20358	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.800142
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MPDZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51073
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98883
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22959
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841408
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838103
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981058
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.934519
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11258
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80287
U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00798
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-69-VJ68_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204357
HIV_Infected-mDC_None_GSE42058	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.15912
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02672
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282455
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32383
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2355
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.34688
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31832
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888529
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.976658
hsa-miR-513a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64652
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55331
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21225
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2715
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Prostate adenocarcinoma_PRAD_TCGA-2A-A8W1-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BJ-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiomyopathy, Dilated_Myocardial tissue_GSE3586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.40039
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09402
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LH-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7482-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10105
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17725
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2294
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0639
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02156
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8156
multicellular organismal development	GO Biological Process Annotations 2015	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89675
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.059373
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5415
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80287
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5928
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1309
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37466
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942397
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7608835-aba3058_Table_S5.xlsx-RING1B_EWS-FLI1_ACTIVATED-RING1B_EWSR1-FLI1_activated_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33434
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
DNAJC2	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4699-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921182
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04186
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61884
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36281
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950639
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04198
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10343
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37894
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42712
TC32	CCLE Cell Line Gene Expression Profiles	1.0	2.0483
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9403
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.438635
ONCODG1	CCLE Cell Line Gene Expression Profiles	1.0	1.34855
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88258
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69004
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1322	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33302
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JA-79-II25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226031
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11136
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49552
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.10145
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039439
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15432
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05129
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1499
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
PDE10A_KO_GDS4542_292_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852854
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03149
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
Embryonic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83458
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0857
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1008
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35783
MCM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2945
biological_process	GO Biological Process Annotations 2015	1.0	null
COLO320	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4193
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41739
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55756
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular response to oxidative stress	GO Biological Process Annotations 2025	1.0	null
BUB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62777
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6522
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OC-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16494
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48803
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17837
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21021
dorsolateral part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46586
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82197
MEG-01	COSMIC Cell Line Gene CNV Profiles	1.0	2.15726
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
collicular (rostral) midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25022
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.837207
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01968
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11037
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41904
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM111B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05928
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27729
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glioblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx AdiposeTissue 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	5.13158
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9299
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
Oc cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10253
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
19377508-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.918868
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1635
Lung adenocarcinoma_LUAD_TCGA-86-A456-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.40252
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34125
hsa-miR-146b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00193
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3146	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
organelle	GO Cellular Component Annotations 2015	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27574
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902879
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78673
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05349
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18997
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1584
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17335
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66299
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2594
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
P63_DEPLETION_GDS2534_63_human_ME180 cervical carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23888
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946028
Regulation of gene expression and signal transduction	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
KARPAS-1106P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88143
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74378
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.74428
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311679
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9611
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.121
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608124
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36768
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18675
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22151
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06511
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16305
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69594
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22242
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLI3T_Lipofectamine transfection_GDS4346_616_human_Panc-1 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33116
SAP30	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19242
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15232
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	1.0	1.7477
bortezomib_homo sapiens_gpl10558_gds4089	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831447
poly-pyrimidine tract binding	GO Molecular Function Annotations 2023	1.0	null
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200901
PMC10558344-mmc1.docx-3-ZNF670_ZNF670	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6347
KDM5B	ENCODE Transcription Factor Targets	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27299
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986864
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33859
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3853
JHUEM3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32097
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IFIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09851
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.8072
SLC2A4RG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84013
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15258
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941227
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23002
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34666
Nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CLDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09872
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01316
DNAAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36234
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8530322-pone.0258316.s002.xlsx-GG_776_TH17-AA_776_TH17-Symbol_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
USP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89891
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.97498
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37973
H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WM-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32744
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44266
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null