association	dataset	threshold value	standardized value
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84628
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55188
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.892489
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99742
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15083
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7067-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21015
VKORC1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27408
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41785
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74292
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96735
Lung adenocarcinoma_LUAD_TCGA-MP-A4T7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33441
biological_process	GO Biological Process Annotations 2015	1.0	null
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28315
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.46345
Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2122	CCLE Cell Line Gene CNV Profiles	1.0	1.50922
Perturb_13015_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.80995
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78592
Brain Lower Grade Glioma_LGG_TCGA-W9-A837-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.694
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27366
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1574
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63281
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14358
KDM5A	ENCODE Transcription Factor Targets	1.0	null
20035825-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
abnormal immunoglobulin level	GWASdb SNP-Phenotype Associations	1.0	0.942765
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08556
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18785
internal globus pallidus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36907
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14313
MXI1	ENCODE Transcription Factor Targets	1.0	null
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85307
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02617
Lymphoid cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14859
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04799
Perturb_6561_KO_Stxbp5l_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.683
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62564
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862374
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15483
SNAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34312
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W7-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82639
WSUDLCL2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49957
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47516
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.12246
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03854
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7416
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843053
JADE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2078
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Site of DNA damage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59945
t30-blood-rna_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.92323
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6036
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_POU5F1_16518401	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37285
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.822
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.83975
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9791
MutSgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.057
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.731
CEBPB	ENCODE Transcription Factor Targets	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased male germ cell number	MGI Mouse Phenotype Associations 2023	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3269
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28146
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23384
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22606
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40218
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29502
Brain Lower Grade Glioma_LGG_TCGA-DH-A66F-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pairing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.976
Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2953
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40898
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03138
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	0.808534
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9441
female gamete generation	GO Biological Process Annotations 2025	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LLPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47196
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33711
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.54867
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Sperm cytoplasmic droplet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47348
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45486
Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW22	DepMap CRISPR Gene Dependency	1.0	2.51273
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3256
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08286
PCI30	DepMap CRISPR Gene Dependency	1.0	2.34418
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51311
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y5-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89885
Secondary motor area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33434
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
FAM236B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47945
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79943
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0413
MYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87699
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29502
Null cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
PRNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37635
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92719
ZC3H11A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.216
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC16A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34759
Perturb_4346_KO_Tln1_SRP378238	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.24108
Spermatoproteasome complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
t69-brown-adipose_female_4w	MoTrPAC Rat Endurance Exercise Training	1.0	4.71672
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6696
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4518
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22392
GSE183271_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell cycle	GO Biological Process Annotations 2015	1.0	null
GSE129465_3_v_2_phf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6716
Swi5-Sfr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
Brain Lower Grade Glioma_LGG_TCGA-RY-A840-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.89572
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.58223
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.20774
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11144_KO_Klf14_ERP010756	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.94507
UGT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13217
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	0.205052
Chlamydia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54573
r3 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51137
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.072301
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
mood disorder	GWASdb SNP-Disease Associations	1.0	0.283976
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58926
HSFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68872
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35239
Perturb_16746_KO_Ly6e_SRP250973	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35985
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.54368
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1763
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Myelencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.626
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8149
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03262
Lung adenocarcinoma_LUAD_TCGA-MP-A5C7-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34509
TXNDC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78441
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09036
RELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32824
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Subcortical maternal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
abnormal male meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ARRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57688
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51817
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
Perturb_11792_KO_Ctdspl_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86264
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4155
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79843
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.47698
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
Elementary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04766
Perturb_7329_OE_MOV10_SRP120600	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.89345
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67051
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54994
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14925_OE_HsATXN3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4547
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47812
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS27	DepMap CRISPR Gene Dependency	1.0	2.50755
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87021
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
synucleinopathy	GWASdb SNP-Disease Associations	1.0	0.918934
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.99609
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843053
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04839
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16955
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77658
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE184133,GSE184137_2_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WL-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14923_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.76406
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06981
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10910_KO_Thbs1_SRP276889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06961
prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
intermediate stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56703
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r4 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01239
intermediate stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28025
Nurse cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.027
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27733
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	0.808534
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.072
BE2M17	DepMap CRISPR Gene Dependency	1.0	2.34649
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13088
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9988
NCIH1944	CCLE Cell Line Gene Expression Profiles	1.0	1.93802
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72389
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.014
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33972
Trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.18
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SUMO-targeted ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
Perturb_15236_KO_Scl/Tal1/Lyl1_SRP179031	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.60365
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08429
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31089
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
RAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12917
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26547
Perturb_5294_KO_Dgcr8_SRP137730	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.71048
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.8914
disease	GWASdb SNP-Disease Associations	1.0	0.039866
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15628
Epithalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
TERF2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60615
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00772
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10499
erg_19359602_huvec_lof_human_gpl570_gds3557	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.527642
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11281
WM2664	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46515
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43335
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24767
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.352
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36192
Perturb_13631_KO_Runx3_SRP133503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.3299
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53969
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01131
Perturb_4730_Mut_Tardbp_SRP133158	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55023
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.66001
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07858
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Protein phosphatase 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.263
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-A7CR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74553
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.27
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9351
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69205
Egg coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.314662
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8197
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.615
DNA polymerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.977
RecQ family helicase-topoisomerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.341
Fanconi anaemia nuclear complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.677
Perturb_5868_KD_Cpsf6_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5926
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3978
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.835064
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70972
ZNF280D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14466
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36093
CCIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85855
male infertility	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_5867_KD_Cpsf6_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
decreased secondary ovarian follicle number	MGI Mouse Phenotype Associations 2023	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE183474_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_EBF1-Unnamed_6_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9765_KO_Ikbkb/Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.17624
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30027
DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.593
Nucleus lentiformis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10672
Parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31784
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.463519
abnormal female meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77803
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.151764
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98092
anterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45185
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997182
mantle zone of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16183
UT7	CCLE Cell Line Gene Expression Profiles	1.0	1.51087
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20094
CTXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03674
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	1.92203
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9635
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43934
Caudate nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.679
chromosome	GO Cellular Component Annotations 2025	1.0	null
Distal arthrogryposis type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUN-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11740_KO_Trp53_SRP221563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.89993
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95443
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0852
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37573
TE6	CCLE Cell Line Gene CNV Profiles	1.0	1.69567
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VAC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53464
Lung adenocarcinoma_LUAD_TCGA-55-8085-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3297
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78047
GSE163052,GSE163198_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7196
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54754
CDC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.933029
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25803
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78682
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97245
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28063
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35491
SAOS2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7473
FN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82375
MAGEE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26807
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995427
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
TTC549	DepMap CRISPR Gene Dependency	1.0	2.83081
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.036
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2726
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15364
Perturb_13017_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.49261
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
20035825-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97798
P4HA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73074
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67399
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53699
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4765-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-2.38967
abnormal seminiferous tubule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
LMO2	ChEA Transcription Factor Targets	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6316
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7177
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.6333
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.182
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00499
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
Turner syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
BRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79091
hematologic cancer	GWASdb SNP-Disease Associations	1.0	1.07599
KANSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
meiotic DNA double-strand break formation	GO Biological Process Annotations 2025	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16408
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.260616
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03051
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24344
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYP2U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20452
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82878
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.1626
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22511
small seminiferous tubules	MGI Mouse Phenotype Associations 2023	1.0	null
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POU2F1-35413990-HUMAN-ARNEGCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923118
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.122
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pararubral nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27785
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21551
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4775-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63499
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.042717
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12986
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02532
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9759
DNA polymerase III, clamp loader complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
STK33_NOMO	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25941
ELF1	ENCODE Transcription Factor Targets	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66435
cellular process	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM253	DepMap CRISPR Gene Dependency	1.0	4.49745
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45583
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40051
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CFLAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37876
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12991
ZNF879	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26692
Perturb_13009_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.65981
Perturb_10972_KO_Ctdspl_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84539
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15712
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	1.20411
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52349
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76376
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.61938
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.178
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.43752
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.046711
Ovariole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
Perturb_17440_Mut_Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.1115
nuc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843053
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28218
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62361
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.97216
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4798
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89232
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
depression	GWASdb SNP-Phenotype Associations	1.0	0.354404
GATA2	ChEA Transcription Factor Targets	1.0	null
POU2AF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30304
Perturb_12791_KO_Trem2_SRP124787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.2875
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.97695
NCIN87	DepMap CRISPR Gene Dependency	1.0	4.90544
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63267
TAL1	ChEA Transcription Factor Targets	1.0	null
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73023
Sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
IM95	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3627
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74282
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51884
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60456
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.40725
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.155226
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96438
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2856
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90178
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55188
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8963
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9113
LC1SQSF	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47602
Cerebral peduncle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.507
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14199
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.89791
PRR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50507
ERICH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29963
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94019
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5505
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31376
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16156
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.913
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of humoral immunity	GWASdb SNP-Phenotype Associations	1.0	0.332291
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31205
GSE148066,GSE157787_2_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01335
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2346
MCC142	DepMap CRISPR Gene Dependency	1.0	2.36874
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69592
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863221
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dna metabolic process	GO Biological Process Annotations 2015	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3887
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73161
pallidum (globus pallidus complex)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16138
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19809
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80699
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59664
Cold medicine-related Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) with severe ocular complications	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20698
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	0.808534
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10078
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65482
Perturb_10960_KO_Apof_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.40815
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25798
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPMI8226	CCLE Cell Line Gene CNV Profiles	1.0	1.60929
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.095
COX6B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26079
bone disease	GWASdb SNP-Disease Associations	1.0	0.105848
Perturb_2231_KO_Irs1_SRP125007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.28278
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19014
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9293_KD_Stat1|Stat1_SRP254967	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84874
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PTPN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98953
Cerebrovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
METTL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3989
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23325
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5808
Perturb_10962_KO_Arl10_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.64984
Perturb_10979_KO_Dusp13_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.13421
arthritis	GWASdb SNP-Disease Associations	1.0	0.234457
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58897
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28921
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53564
Perturb_10848_KO_Pparg_SRP289705	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.14642
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G6-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11145_KO_1810027O10Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.99774
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98532
Perturb_4695_KD_Srsf3_SRP059321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.49147
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00515
Perturb_1014_KO_Egfr_SRP247491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34389
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10561
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-3615-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55813
TAF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79062
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32313
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1155
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
HT-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.601
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Complete Hydatidiform Mole	DisGeNET Gene-Disease Associations	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_14920_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.81806
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99017
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.1031
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33169
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02584
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LC1SQ	DepMap CRISPR Gene Dependency	1.0	4.58014
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88841
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90333
mRNA_NANOG_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68324
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8816
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.861
Lung squamous cell carcinoma_LUSC_TCGA-34-5232-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32764
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72533
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.092747
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.90972
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50377
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.081178
RNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68672
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85307
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0898
bone	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09446
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.5031
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
me96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.049
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5999
GGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02932
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7485
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17892
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7414-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMK1	DepMap CRISPR Gene Dependency	1.0	6.02616
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.036
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Z-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2952
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8546
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31784
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
SIMA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48538
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39137
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04966
DYNC2I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05314
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
MRPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04831
NCIH2196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47459
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58128
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53588
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.353
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
18787207-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
abnormality of b cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.408206
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50091
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09276
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	8.66242
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81232
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.223
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61827
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962196
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20458
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4739-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.05
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8122
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10782
Brain Lower Grade Glioma_LGG_TCGA-QH-A6X5-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0853
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Marrow cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17109
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905571
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160246_2_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34972
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHRAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34202
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14354
Perturb_11780_KO_Apof_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.51569
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20109
LOUNH91	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58955
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77155
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55377
Prostate adenocarcinoma_PRAD_TCGA-HC-7750-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large granular lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
free-living state	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.39413
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53186
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.272
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
ASTRA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
MM160113	DepMap CRISPR Gene Dependency	1.0	6.5203
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7645-01A-22R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MC116	CCLE Cell Line Gene Expression Profiles	1.0	1.6529
Heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.036
Perturb_10874_OE_LIPA_SRP328944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.54045
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4604
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4491
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91428
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65873
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34197
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.558
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
ZCCHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47826
Mitotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.379
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25692
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00048
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06072
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68762
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4IJ-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.484
Perturb_14515_KO_Esrrg_SRP331239	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.138
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24869
PECAPJ15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96142
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40207
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
decreased testis weight	MGI Mouse Phenotype Associations 2023	1.0	null
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61628
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.03
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03219
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.4
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09789
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07136
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11989
NR3C1	ChEA Transcription Factor Targets	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
dna recombination	GO Biological Process Annotations 2015	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6236
U937	CCLE Cell Line Gene CNV Profiles	1.0	1.50329
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02292
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
KLF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86836
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7093
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03104
ZNF669	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35288
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85201
Perturb_5292_KO_Dgcr8_SRP137730	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.15616
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38738
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52181
Central element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.814
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15355
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38511
Brain Lower Grade Glioma_LGG_TCGA-DB-A64W-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Midbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.507
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04808
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.833
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.77926
Embryonic brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.549
CBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15143
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.545
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04219
SUDHL4	CCLE Cell Line Gene Expression Profiles	1.0	1.6867
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58862
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.402
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10801
TCEA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2598
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ONECUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6369
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30338
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.19648
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0188
nucleus of the stria medullaris (prethalamic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04602
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00955
YY1	ChEA Transcription Factor Targets	1.0	null
ENSG00000170846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69918
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55642
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15628
Perturb_13121_OE_Kras_ERP109041	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45435
Condensin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99694
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5296
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100377_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0944
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13414
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83903
RBMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59716
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.095
ZFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57356
CHD2	ENCODE Transcription Factor Targets	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02269
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.1296
intermediate stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60437
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02915
all	GWASdb SNP-Phenotype Associations	1.0	0.03485
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07652
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66668
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.581
MED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45973
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0857
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36019
Nijmegen breakage syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27015
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	1.53372
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40092
decreased primordial ovarian follicle number	MGI Mouse Phenotype Associations 2023	1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66669
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4041
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2811
ABCC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71318
Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863221
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
GSE154246_2_v_3_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65129
Cerebral gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.614
Pons	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.351
internal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17892
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15483
Perturb_16957_KO_Drp1_SRP173900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.92516
Natural killer cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VSIG10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35089
Set1C/COMPASS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.695
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63913
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EW-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125007,GSE125008_3_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08904
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00989
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60793
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972946
Perturb_16679_KO_SiglecE_SRP350344	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.32817
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80059
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.98368
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13257_KO_Pcgf3_SRP115638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.69423
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.095
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11421
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08851
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.7601
Late recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.195
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06775
limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.818
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51813
Corpus striatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.679
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19618
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
OCIAML3	DepMap CRISPR Gene Dependency	1.0	2.55411
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2542
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6052
SMAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87791
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
CST complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27165
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7873
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.95193
Perturb_13509_OE_Cd79b_SRP234708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.70458
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19573
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.222
PRKACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33848
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12611_Mut_Jak2_SRP075921	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.80495
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13282
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24941
avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.38527
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13273
EEIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10966
r4 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05594
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843053
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5783
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08236
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.03
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96284
NOS1	DepMap CRISPR Gene Dependency	1.0	6.93068
PPARG	ChEA Transcription Factor Targets	1.0	null
basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
NCIH2029	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32493
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.181233
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10158
Perturb_12785_KO_C5ar1_SRP097094	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.29799
intermediate stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50782
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60437
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3461-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24866
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56703
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.036
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02125
brl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
Parabrachial nucleus, lateral division, superior lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11194
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09067
CD59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878609
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
PMC4521181-oncsis201520x8.pdf-50-CSRNP1_CSRNP1	Rummagene Transcription Factor Associations 2026	1.0	null
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54407
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.608
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.632
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58907
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.555
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73249
mantle zone of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10649
SOX10	JASPAR Predicted Transcription Factor Targets	1.0	null
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.859
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94916
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-LI-A67I-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vitellarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-2.85343
LAMTOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54701
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9782_KD_Esrrb_SRP321923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.74994
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Condensed chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.277
Rhp55-Rhp57 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	2.55576
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09246
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1029
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8197
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.581
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01949
alpha-heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.342
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.049962
Lung adenocarcinoma_LUAD_TCGA-78-7160-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-889	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20021
DNA gyrase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.597
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7632
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31646
IFNAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26155
Monocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	1.624
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24594
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11447
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32893
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26628
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.041876
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.42656
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44862
prethalamic eminence	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04602
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
ZNF264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26948
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.405
Linear element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.038
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01478
Exodeoxyribonuclease VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.837
Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10933
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Medulla oblongata	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.626
HCFC1	ENCODE Transcription Factor Targets	1.0	null
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34952
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F7-01A-11R-A084-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPZOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2274
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.56149
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63233
L1236	DepMap CRISPR Gene Dependency	1.0	3.10205
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J3-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13251_KO_Dux_SRP098643	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.585
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90112
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.046508
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	2.00415
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t69-brown-adipose_female_1w	MoTrPAC Rat Endurance Exercise Training	1.0	9.30633
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84775
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81045
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.40387
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02292
FRMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37724
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86726
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46D-01A-21R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
JHU022	DepMap CRISPR Gene Dependency	1.0	4.24024
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00515
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29251
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.016
Chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.802
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85795
NCIH650	DepMap CRISPR Gene Dependency	1.0	6.82087
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
MORCPR	CCLE Cell Line Gene CNV Profiles	1.0	1.7928
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34959
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90649
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3402
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67825
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.327
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47495
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21474
Cdc73/Paf1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Spleen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.178
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.283
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66668
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8206
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29334
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.504
Subthalamic nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.554
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1497
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HeLa-229 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
ZNF621	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24017
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
Lung squamous cell carcinoma_LUSC_TCGA-98-8023-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90178
Endocrine pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27455
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08787
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9795
Brain Lower Grade Glioma_LGG_TCGA-P5-A5ET-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49469
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5864
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13213_KO_Yap1_SRP059253	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.74621
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900833
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdala	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
VAMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82427
RMUGS	CCLE Cell Line Gene CNV Profiles	1.0	2.12351
Brain Lower Grade Glioma_LGG_TCGA-DH-A7US-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03999
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38598
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.547
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50363
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13284
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10158
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1701
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27401
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69719
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92109
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13102
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12991
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.309
YH13	CCLE Cell Line Gene CNV Profiles	1.0	1.84873
Perturb_15669_KD_Hnrnpf_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.40807
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78244
GSE134191_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41531
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37117
abnormal double-strand DNA break repair	MGI Mouse Phenotype Associations 2023	1.0	null
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20018
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38311
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61I-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6084
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	2.05456
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862374
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18964
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.39453
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43471
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.554
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30679
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47003
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.329
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26498
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45262
Zeta DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
NCIH1155	CCLE Cell Line Gene Expression Profiles	-1.0	-2.66546
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59839
KP4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36958
mRNA_ESRRB_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57229
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2321
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.35853
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034942
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25078
CAPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74154
dorsal part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0413
Atrial fibrillation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6699
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51884
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.554
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5317
ZNF100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91008
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00008
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15235_KO_Scl/Tal1_SRP179031	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69561
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86942
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	4.22055
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25322
Endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37215
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
Granuloma inguinale	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31489
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1743
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79411
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22015
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.97695
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843053
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48751
Early recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.285
mantle zone of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44535
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08152
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06207
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60628
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25997
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.062
Bronchial epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.405
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
KP2	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18625
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30909
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.222
Perturb_1109_KO_Nkx2_SRP032537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.2441
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7837-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15675_KD_Hnrnpf_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.81312
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22635
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34493
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mononuclear phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02904
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.864454
Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2297
KIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30369
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17242
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10649
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
S117	DepMap CRISPR Gene Dependency	1.0	2.11933
NCIH1155	DepMap CRISPR Gene Dependency	1.0	3.33121
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mre11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.19
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64948
RPMI8226	DepMap CRISPR Gene Dependency	1.0	4.22224
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04857
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.1626
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996474
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15979
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9509
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1202
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
cb95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.087
COV434	CCLE Cell Line Gene Expression Profiles	1.0	1.58946
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61709
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.127458
abnormal ovary morphology	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11914
NDUFA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89741
NUMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49858
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7743
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0228
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13273
Brain Lower Grade Glioma_LGG_TCGA-DB-A64U-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epithelium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.405
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66236
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50749
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28638
mantle zone of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04602
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33215
HCC1599	CCLE Cell Line Gene Expression Profiles	1.0	3.40787
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.05895
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.55752
COLO741	CCLE Cell Line Gene CNV Profiles	1.0	1.98764
single-organism process	GO Biological Process Annotations 2015	1.0	null
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84591
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33399
SNU899	CCLE Cell Line Gene Expression Profiles	1.0	1.40948
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95577
Perturb_9294_KD_Stat1|Stat1_SRP254967	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.42682
46 XX gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
ZNF684	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20179
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43891
Perturb_17316_KO_Tardbp_SRP321767	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.21957
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6733
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.60173
SEC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22397
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38326
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ADPGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16777
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86967
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.858
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
Lung adenocarcinoma_LUAD_TCGA-78-7148-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863221
DNA packaging complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.943
Germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16122
striatum (corpus striatum)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10517
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57556
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94303
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98233
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart	GTEx Tissue Gene Expression Profiles	1.0	2.18089
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9223
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59339
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Childhood germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06624
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.08286
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20544
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00231
meiotic cell cycle	GO Biological Process Annotations 2015	1.0	null
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4049_KO_Pde1b_SRP260102	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52805
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80869
NCIH1385	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80759
Dendritic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.178
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12651
Meiotic recombination protein REC114-like	InterPro Predicted Protein Domain Annotations	1.0	null
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22587
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42376
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.91889
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Kidney Chromophobe_KICH_TCGA-KN-8435-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.060002
Perturb_6177_KO_Bmal1_ERP113681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.82303
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27036
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS229T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5688
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06921
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25931
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68268
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.409
OVMIU	DepMap CRISPR Gene Dependency	1.0	6.51177
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.608
Annulate lamellae	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43249
LN428	CCLE Cell Line Gene Expression Profiles	1.0	1.4525
NCIH647	DepMap CRISPR Gene Dependency	1.0	4.92004
Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Perturb_3402_KO_Cbfb_SRP214434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.98026
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5883
Prostate adenocarcinoma_PRAD_TCGA-EJ-5515-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.795
abnormal meiosis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE134191_6_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43934
Perturb_4163_KO_Aki2_SRP325507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.45222
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30027
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23473
Bronchial epithelial cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.405
Perturb_3403_KO_Cbfb_SRP214434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.54307
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4756
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3965
SYK_druginhibition_285_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.32876
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77771
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1513
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MutS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.272
hsa-miR-4266	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45547
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14358
rheumatoid arthritis	GWASdb SNP-Phenotype Associations	1.0	0.444551
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.176
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61897
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02515
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2477
DDX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23791
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.508
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18371
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27165
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31316
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45627
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
XY body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.126
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63297
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46813
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10825
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.25
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PCDHB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23506
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.155
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.9253
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5185
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	4.26426
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0845
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43063
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84045
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.895
Brain Lower Grade Glioma_LGG_TCGA-DB-A75K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GI1	DepMap CRISPR Gene Dependency	1.0	2.05938
ZNF454	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15637
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
Nuclear meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.065
Sporulating cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18473
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.5682
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64737
MAX	ENCODE Transcription Factor Targets	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25739
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5007
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67508
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1261	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Endodeoxyribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.188
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53418
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64948
Perturb_10963_KO_Asb15_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.73678
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04935
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22298
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17758
Perturb_1895_KO_Trem2_SRP173901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.236
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71114
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	2.11538
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47465
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5639-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal spermatogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00172
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59074
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.73511
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32036
PMC7846764-41598_2021_81773_MOESM2_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32092
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13965
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30582
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.657
CAS1	DepMap CRISPR Gene Dependency	1.0	2.28772
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.668
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35162
hsa-miR-369-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
mRNA_SALL4_19060217	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.166
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94571
abnormal oogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3053
Leukocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
YY1-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CD320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99887
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-7966-11A-01R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78285
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12142
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57564
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C5-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4264
NCIH2081	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57288
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62092
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12916_KO_Cbfb_SRP214434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.61364
Polytene chromosome chromocenter	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
Perturb_3366_KO_Tet2/Tet3_SRP056118	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.21618
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5293_KO_Dgcr8_SRP137730	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8953
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79286
Kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.277
NCIH226	CCLE Cell Line Gene Expression Profiles	1.0	2.12859
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBE2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98259
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20206
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10283
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2496
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51868
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40841
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26021
PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-5143-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14924_KO_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.48596
Phosphoribosylaminoimidazole carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9077
OCUM1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5206
Reticulate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.195
Perturb_11812_KO_Mcam_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.87518
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07278
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
NO11	DepMap CRISPR Gene Dependency	1.0	5.40075
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0881
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_1812_KO_N4bp1_SRP255180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.475
NCIH1755	DepMap CRISPR Gene Dependency	1.0	4.44331
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
Perturb_17442_OE|Mut_Tal1|Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.07213
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29572
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14447
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86335
Medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02904
Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00426
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73011
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0044
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CORL279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48206
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16557
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
USF2	ENCODE Transcription Factor Targets	1.0	null
Perturb_10957_KO_Adig_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.87216
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.608
Germarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
Site of double-strand break	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
Perturb_2025_KO_Runx1c_SRP058396	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.47907
496100360_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26471
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.97695
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99468
STK33	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
t69-brown-adipose_female_8w	MoTrPAC Rat Endurance Exercise Training	1.0	4.44591
Perturb_13108_KO_Mbnl1/Mbnl2_SRP045573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.41589
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0915
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843053
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCM8-MCM9 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
r5 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18518
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28218
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77403
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.20774
Lung adenocarcinoma_LUAD_TCGA-62-A470-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.926
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08038
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.127458
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24391
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68621
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34202
abnormality of lymphocytes	GWASdb SNP-Phenotype Associations	1.0	0.36461
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
immune system disease	GWASdb SNP-Disease Associations	1.0	0.066651
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843053
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.60173
Cingulate gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.614
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.05074
abnormality of cell physiology	GWASdb SNP-Phenotype Associations	1.0	0.332291
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4017
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1836	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9297
Meiotic recombination initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.621
Brain Lower Grade Glioma_LGG_TCGA-TM-A84M-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1463	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34729
UMUC1	DepMap CRISPR Gene Dependency	1.0	2.19323
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06087
Distal arthrogryposis type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26473
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9628
C19orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0522
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91491
Peripheral blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.178
Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15684
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
IL2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72936
TEN	DepMap CRISPR Gene Dependency	1.0	2.13424
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22273
mantle zone of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1458
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15543
YH13	CCLE Cell Line Gene Expression Profiles	1.0	2.2537
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900833
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2487
Commensal bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Perturb_14921_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.55543
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29502
liminal part of r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44859
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
LNZTA3WT4	DepMap CRISPR Gene Dependency	1.0	2.07169
Hereditary nonpolyposis colorectal cancer type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.55
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77732
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6133
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0877
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19014
t30-blood-rna_male_8w	MoTrPAC Rat Endurance Exercise Training	1.0	1.4331
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
FPGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10902
ZER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41512
t69-brown-adipose_female_2w	MoTrPAC Rat Endurance Exercise Training	1.0	6.3691
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.992
CUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53573
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64748
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35988
GSE183271_5_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.796
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17633
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE8	CCLE Cell Line Gene CNV Profiles	1.0	1.56393
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7389-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5172_KO|KD_Sirt1|Otx2_SRP075247	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Holliday junction resolvase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70929
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.087982
Hematopoietic cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
atf1-pcr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.689
PRDM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49608
metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39958
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38256
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.83935
NDUFS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38609
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61919
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30922
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0365
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44779
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32706
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863221
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3503
EPHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30507
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40961
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.845
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15483
496100343_TCx_possible Alzheimer's disease_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02132
KCNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92972
ZNF717	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52355
abnormal chromosomal synapsis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8829
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	5.1949
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33202
Karyomegalic interstitial nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66528
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18245
Perturb_10949_KO_18O10Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06922
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0118
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24209
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-322-ZNF48_ZNF48	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SH-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3967
16705683-table2	GeneSigDB Published Gene Signatures	1.0	null
GSE154246_2_v_0_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11834_KO_Rilp_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.35124
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75638
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WP-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.484
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36245
MARCHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38745
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95183
NP8	DepMap CRISPR Gene Dependency	1.0	2.27658
Perturb_16850_KO_Hnrnph1_SRP068520	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.77852
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	1.0	1.36088
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	1.53746
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.27271
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stevens-Johnson syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.581
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37903
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	1.8023
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94393
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46862
E2F6	ENCODE Transcription Factor Targets	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22631
LinE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95502
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17686
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40182
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36719
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.84042
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5304
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92596
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13102
Shu complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30071
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33711
KKU100	DepMap CRISPR Gene Dependency	1.0	4.21588
Tourette syndrome	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5434-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3921
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
EFE184	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58012
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.041215
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.2466
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96215
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.036
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
Koelliker-Fuse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52636
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Slx1-Slx4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33183
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PROSER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10554
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78685
Perturb_5871_KD_Nudt21_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.74967
CIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30734
Perturb_13021_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86454
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
HILPDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39002
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900833
Cingulate cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.614
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11989
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.65
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7588-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85231
SEM	DepMap CRISPR Gene Dependency	1.0	5.15252
Parabrachial nucleus, lateral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36865
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59988
PANC0213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01588
Parenchyma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.088
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
abnormal synaptonemal complex	MGI Mouse Phenotype Associations 2023	1.0	null
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	2.23244
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47563
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962196
Perturb_18563_KO_Tal1_SRP117185	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69561
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09055
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.60727
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.074
Perturb_2237_KO_Malat1_SRP193997	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.52302
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79982
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.058923
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.954179
rheumatoid arthritis	GWASdb SNP-Disease Associations	1.0	0.52115
RAD21	ENCODE Transcription Factor Targets	1.0	null
decreased primary ovarian follicle number	MGI Mouse Phenotype Associations 2023	1.0	null
Lymphogranuloma venereum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
oogenesis	GO Biological Process Annotations 2025	1.0	null
ACSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10026
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15628
Perturb_12697_KO_Ezh2_SRP222765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.58437
MALME3M	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61056
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82611
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.782
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4167
Perturb_6953_KD_Rbm20_ERP122940	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99248
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26122
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93333
Adrenocortical carcinoma_ACC_TCGA-OR-A5KY-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77204
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46621
female infertility	MGI Mouse Phenotype Associations 2023	1.0	null
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87887
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6508-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.47276
Perturb_10988_KO_Gnpda2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.69561
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96849
NCIH1568	CCLE Cell Line Gene CNV Profiles	1.0	1.7825
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8461
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27595
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5440-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9426
MIS12/MIND type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_13258_KO_Pcgf3/Pcgf5_SRP115638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.22391
Perturb_1882_KO_Nelfb_SRP132312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33918
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6883
beta-heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Phagocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23794
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2047
EZH2	ENCODE Transcription Factor Targets	1.0	null
SLR25	CCLE Cell Line Gene Expression Profiles	1.0	2.40709
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5080-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4884
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.064088
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14441
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17983
abnormal testis morphology	MGI Mouse Phenotype Associations 2023	1.0	null
mania	GWASdb SNP-Phenotype Associations	1.0	0.463519
Mitotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.405
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6958
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59958
dorsal periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1458
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.815
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
immune system cancer	GWASdb SNP-Disease Associations	1.0	0.147944
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12696
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.97216
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.282
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	1.07599
NRBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37216
ZNF749	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50837
parkinson's disease	GWASdb SNP-Disease Associations	1.0	0.918934
Acute Myeloid Leukemia_LAML_TCGA-AB-2912-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932529
Avian pallium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.095
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98661
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8587
CEP131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20703
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.072
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2965
PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
PSS131R	DepMap CRISPR Gene Dependency	1.0	2.03565
intermediate stratum of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04602
Stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.117329
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.065273
KYSE410	DepMap CRISPR Gene Dependency	1.0	2.19066
Mononuclear cell	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.367
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7415-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94613
UMUC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40963
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3316-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70295
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
liminal part of the r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14828
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91181
Somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.704
Lung function (FEV1/FVC)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.91549
abnormality of b cells	GWASdb SNP-Phenotype Associations	1.0	0.408206
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11172
SMAD4	ChEA Transcription Factor Targets	1.0	null
DNA metabolic process	GO Biological Process Annotations 2025	1.0	null
C12orf4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54344
Neostriatum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.679
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23325
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10229
Nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.538
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
RGPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2167
GSE217132_0_v_1_pfkfb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54187
Pineal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.18
em2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79922
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39853
MutLbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
H2BW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51563
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
ATP5PO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59853
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2467
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78681
SMUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31954
Pericentric heterochromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
MutLgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.812
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
Globus pallidus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.299
Lung squamous cell carcinoma_LUSC_TCGA-98-A53A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05604
Perturb_10984_KO_Fam20a_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.88452
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5802
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cancer	GWASdb SNP-Disease Associations	1.0	0.047292
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0998
TBP	ENCODE Transcription Factor Targets	1.0	null
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37874
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3629
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.34495
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1228
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNMT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5498
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06213
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63129
RAJI	CCLE Cell Line Gene Expression Profiles	1.0	1.50937
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.229
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.0329
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22302
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4078-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.669
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Pancreatic islet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.135
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.90178
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Fibre tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.507
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6581
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00217
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52072
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91491
PEO4	DepMap CRISPR Gene Dependency	1.0	4.65437
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.615
SMC3	ENCODE Transcription Factor Targets	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57456
abnormal spermatocyte morphology	MGI Mouse Phenotype Associations 2023	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4446
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13102
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.58178
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75641
Atrial fibrillation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.036
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3382
Sporophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
HNF1B	JASPAR Predicted Transcription Factor Targets	1.0	null
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20608
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0845
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1122
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18384
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36528
LRP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15112
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46798
SUZ12	ENCODE Transcription Factor Targets	1.0	null
SNU1033	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83288
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24209
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08197
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6716
Perturb_18562_KO_Lyl1/Tal1_SRP117185	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.60365
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16547_KO_Dusp6_SRP322434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56141
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45V-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null