association	dataset	threshold value	standardized value
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.7893
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2642
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.3381
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54228
bone marrow	HPA Tissue Protein Expression Profiles	1.0	0.72428
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.5691
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8939
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78282
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2023	1.0	null
JC-02-ZR15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285164
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4613
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-2.25244
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3382
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.964996
Perturb_307_KD_TPRX1/TPRX2_SRP361145	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.95611
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.657197
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.585421
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5674
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12809
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.233874
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10944
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.59316
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.25244
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1146
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62574
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2531
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44566
Extracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.850151
regulation of viral entry into host cell	GO Biological Process Annotations 2023	1.0	null
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824862
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.323801
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54419
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31414
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850279
Cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.8666
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.72428
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.915969
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.228
496100525_TCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39295
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0203
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99636
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2713
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940695
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6223
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28399
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0942
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.38225
stomach	HPA Tissue Protein Expression Profiles	1.0	0.72428
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.833
Concanavalin A-like lectin/glucanase domain	InterPro Predicted Protein Domain Annotations	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.72428
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275836
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.239995
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6456
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.42459
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1968
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4169
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.0849
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6171
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100360_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52611
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0758
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27373
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3396
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.612883
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8888
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21581
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282319
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.72428
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15873
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24778
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
regulation of cellular localization	GO Biological Process Annotations 2023	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0522
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.443
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.443
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE246660_1_v_0_lmo3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE192771_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5002
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8392
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37592
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9531
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.331159
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.9538
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93548
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.8265
Brain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0294
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25946
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.561752
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.411512
Zinc finger, RING/FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24778
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96933
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.589
Perturb_2126_KO_SUMO1_SRP299611	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5976
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8115
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851269
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1159
GD-46-BU97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2596
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6083
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31414
positive regulation of DNA-binding transcription factor activity	GO Biological Process Annotations 2023	1.0	null
Lymphoid tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3472
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2762
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15873
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2778
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5655
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.72428
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5656
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350214
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5863
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-19q13_43_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
AD-06-OB47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244938
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3877
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5168
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8277
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.7856
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6454
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7488
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.321896
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.737026
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913396
Liver-liver dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	0.606339
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.176
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.64289
adrenal gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.00137
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8222
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.917918
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.522
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MFE-280	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.678473
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6244
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Butyrophylin-like	InterPro Predicted Protein Domain Annotations	1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-A_FUS-DDIT3_vs_both_controls-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68844
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.642761
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30425
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2607
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.725596
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.225569
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9483
regulation of protein localization	GO Biological Process Annotations 2023	1.0	null
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE191022,GSE191031_0_v_1_igf2bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.779048
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228113
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.278414
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2527
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.518102
chr19_55759309_G_C_b38	GTEx eQTL 2025	1.0	1.73838
PMC8120133-supplementarytables_ddab063.xlsx-Table_S2-Table_S2_Differentially_expressed_genes_in_DUX4-fl_and_DUX4-s_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91511
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2875
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02005
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2031
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4683
Immune system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301498
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3499
positive regulation of I-kappaB kinase/NF-kappaB signaling	GO Biological Process Annotations 2023	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.37811
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9011
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859266
QB-42-MC63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.25573
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3038
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30696
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2165
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.473855
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15744
regulation of viral life cycle	GO Biological Process Annotations 2023	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2483
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5861
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20772
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19242
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00449
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93132
Perturb_2138_KO_ASCC3_SRP282634	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4513
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6279
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24668
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1316
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4986
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.378437
Isoamylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.91
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9424
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.99745
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6885
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5576
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.645
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850279
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203084
496100664_HIP_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26941
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.775
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3947
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5244
Digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1315
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.395641
spleen	HPA Tissue Gene Expression Profiles	1.0	1.13988
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2258
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3396
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275572
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0089
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37592
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81767
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4315
protein kinase binding	GO Molecular Function Annotations 2023	1.0	null
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3059
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52979
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2001
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.00137
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.37152
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7486
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9526
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10944
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989458
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2023	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375585
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.76278
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65786
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.566991
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5576
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.123
RDM domain, Ret finger protein-like	InterPro Predicted Protein Domain Annotations	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9876
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22134
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1827
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-848-ENSG00000197483_ZNF628	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20613
colon	HPA Tissue Protein Expression Profiles	-1.0	-0.917918
kinase binding	GO Molecular Function Annotations 2023	1.0	null
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250884
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.712721
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.358333
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223665
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7217
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4065
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0875
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.306958
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4132
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.2757
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.72428
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.585107
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5763
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9477
496100342_PCx_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28842
molecular_function	GO Molecular Function Annotations 2015	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21003
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.572607
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.494384
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934462
modulation by symbiont of entry into host	GO Biological Process Annotations 2023	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE115542_5_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0685
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.850109
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.628303
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24778
positive regulation of NF-kappaB transcription factor activity	GO Biological Process Annotations 2023	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0361
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.425992
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15873
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.03684
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.32066
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.648182
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.364981
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.00168
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30696
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.787203
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9875
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.417673
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4642
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913396
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7372
rectum	HPA Tissue Protein Expression Profiles	1.0	0.72428
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.95234
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.720783
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07279
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.367494
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.553054
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3662
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-1.00137
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6556
GCIY	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21003
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.21291
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8123
B30.2/SPRY domain	InterPro Predicted Protein Domain Annotations	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.396679
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92244
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1177
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.991127
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901463
ubiquitin protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	0.72428
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11325
prostate	HPA Tissue Protein Expression Profiles	1.0	0.72428
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7454
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13427
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4141
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5013
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18687
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.403488
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.39209
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
regulation of autophagy	GO Biological Process Annotations 2023	1.0	null
Extracellular isoamylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.797
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3274
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8396
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2255
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7037
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.372639
SPRY-associated	InterPro Predicted Protein Domain Annotations	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.53591
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298539
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10944
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91255
PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP	Rummagene Transcription Factor Associations 2026	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99636
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.0467
cation binding	GO Molecular Function Annotations 2015	1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.559102
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0483
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9258
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10944
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325925
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0522
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.344
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.304399
496100623_PCx_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21127
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99636
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1835
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859266
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91255
liver	GTEx Tissue Gene Expression Profiles	1.0	1.79896
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.72428
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.788
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18783
protein homodimerization activity	GO Molecular Function Annotations 2023	1.0	null
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.725056
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.385
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1031
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.06629
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914119
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851269
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8804
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9309
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.443
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1803
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4803
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.882791
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
Cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ion binding	GO Molecular Function Annotations 2015	1.0	null
Head	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5231
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.97232
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.021
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.917918
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.412709
PMC11982601-IMM-175-84-s005.xlsx-Fig5D_LPS-Innate_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7254
placenta	HPA Tissue Protein Expression Profiles	1.0	0.72428
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bone marrow	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.375324
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.45591
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.508042
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6045
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1882
GSE138050,GSE148257_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.874532
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.702547
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1352
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0918
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.940695
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31414
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00665
protein polyubiquitination	GO Biological Process Annotations 2023	1.0	null
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	0.72428
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3677
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2783
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0852
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68844
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329513
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.243094
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3829
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913396
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.07
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91255
PMC5446900-NIHMS72240-supplement-Table_S1.xlsx-Table_S1-Table_S1_Genes_differentially_expressed_in_human_primary_myoblasts_upon_ectopic_expression_of_DUX4_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.296853
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7895
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0525
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62798
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.427801
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.531018
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8311
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81698
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839192
protein ubiquitination	GO Biological Process Annotations 2023	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43635
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.551615
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8373
EC-62-OE64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.386655
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08785
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7609
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
Forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
positive regulation of cellular catabolic process	GO Biological Process Annotations 2023	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07629
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26541
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.59
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.934462
Photosensitivity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.101
Zinc finger, RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00128
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.249304
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6141
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2023	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389376
FD-62-ZB67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.282809
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30602
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4598
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9121
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9589
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.252
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6525
SPRY domain	InterPro Predicted Protein Domain Annotations	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297848
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.35
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.29
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0548
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1107
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64545
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4877
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.860102
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.315
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5108
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.347604
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4699
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.8701
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10944
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2039
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308452
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0522
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.416388
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20613
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9971
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9738
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.72428
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2246
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-1.00137
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271439
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.389047
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5839
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5218
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218452
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967125
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20772
positive regulation of autophagy	GO Biological Process Annotations 2023	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.403615
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82029
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36145
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03516
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8575
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99636
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309642
regulation of I-kappaB kinase/NF-kappaB signaling	GO Biological Process Annotations 2023	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31414
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860237
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2607
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.492458
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.447976
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.892547
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9982
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24778
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839192
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12741
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.433885
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.4751
Central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5902
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56969
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3366
NCI-H250	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14188
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15873
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2092
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5021
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-399-ZNF628_ZNF628	Rummagene Transcription Factor Associations 2026	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67611