association	dataset	threshold value	standardized value
Autosomal dominant hypocalcemia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36204
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5371
Lung squamous cell carcinoma_LUSC_TCGA-77-8146-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.041
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027697
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.2964
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5397
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60045
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02305
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
hsa-miR-133b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
EEIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86131
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7758
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0127
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85821
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59265
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43601
TC32	DepMap CRISPR Gene Dependency	1.0	5.08964
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2707
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9751
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1007
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CY-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	82.25
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73998
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microtubule plus-end	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
TKKK	DepMap CRISPR Gene Dependency	1.0	2.02939
Neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03693
Usher syndrome type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3517
VBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55819
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84273
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.846
Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A66B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99633
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8171
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18255
Prostate adenocarcinoma_PRAD_TCGA-EJ-5495-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.712
normocytic anemia	GWASdb SNP-Disease Associations	1.0	0.822323
congenital hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.822323
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02422
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	11.0567
S117	DepMap CRISPR Gene Dependency	1.0	3.99671
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9467
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.8276
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51827
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68864
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947075
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
RBE	DepMap CRISPR Gene Dependency	1.0	2.17388
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
ASXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37188
Lip epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41673
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28714
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
Heterotrimeric G-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.979
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17772
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5252
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46566
G alpha (i) signalling events	Reactome Pathways 2024	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12556_KO_Sirt6_SRP302465	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.49473
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.792
wc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4165
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5902
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6351-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60427
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24992
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.61
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1043
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16409
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889312
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8438
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997875
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33491
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5209
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8211
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17355
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3854
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
PMC3368389-fphys-03-00095.nxml--RGS_protein_PITX2	Rummagene Transcription Factor Associations 2026	1.0	null
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.259062
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868463
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899467
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.37597
NCIH2009	CCLE Cell Line Gene CNV Profiles	1.0	1.69636
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0386
Site of polarized growth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.35
Dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.783
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82434
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873352
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
Stoma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11716
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4147
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90858
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A781-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D22B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93785
UBTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1852
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72965
ERBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67811
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16409
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
Elaioplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
CTCF	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Y-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8055
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07903
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.993
FSCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83757
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
positive regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
GTPase activity	GO Molecular Function Annotations 2023	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.557
TTC709	DepMap CRISPR Gene Dependency	1.0	4.26801
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16409
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FP-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0741
ETS2_KD_GDS5040_9_human_H441 lung cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50149
Cryptococcosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.526
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
SF-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9904
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6674
TSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62746
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8483
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99486
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1936
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3093
RRAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3991
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1835
Opiate dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.071
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
Aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47929
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4523
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62485
dh14	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Post bronchodilator FEV1	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
JMSU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8796
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96044
HT1197	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93179
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47677
TMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32482
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80724
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06732
IKZF1	ENCODE Transcription Factor Targets	1.0	null
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.226454
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AE-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96961
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0975
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8919
KYAE1	DepMap CRISPR Gene Dependency	1.0	5.9628
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
SLC22A31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08684
496100395_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6373
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I9-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
MUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63333
Corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.735
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98161
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75242
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5331
membrane	GO Cellular Component Annotations 2015	1.0	null
Root quiescent center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825929
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
HUO9	DepMap CRISPR Gene Dependency	1.0	3.45203
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.65582
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31643
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4005
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21242
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
Congenital stationary night blindness 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20616
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JJN3	DepMap CRISPR Gene Dependency	1.0	2.19717
Asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.485
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.23185
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3602
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.943
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895018
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
C32	COSMIC Cell Line Gene CNV Profiles	1.0	2.12931
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.61299
hsa-miR-7	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ANTKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47012
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26179
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58983
Contractile actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
negative regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.239293
hsa-miR-129-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Perturb_16518_KD_Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
SJRH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86872
inner SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01248
ACY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54119
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.239293
MIS12/MIND type complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
PMC10247733-41408_2023_863_MOESM2_ESM.pdf-424-RFX8_RFX8	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiac Purkinje fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6185
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0785
FOXA1_OE_GDS4957_10_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Autosomal recessive spinocerebellar ataxia 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50084
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-5630-01A-01R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
NCIH526	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6861
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5376
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8095
PC-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.14331
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.832
hsa-miR-4803	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	2.20187
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
G alpha (i) signalling events	Reactome Pathways 2014	1.0	null
hsa-miR-1238	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
RNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15428
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6364
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49264
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17687
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14579
hsa-miR-190	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25253
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7982
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1094
MAP3K9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66065
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4571
Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.047
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83189
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.96215
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	2.89117
WM88	CCLE Cell Line Gene CNV Profiles	1.0	1.33668
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6649
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
STARD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
Myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864201
hsa-miR-3675-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
Essential hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
Prostate adenocarcinoma_PRAD_TCGA-EJ-A6RA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9648
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3951
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6047
fg86	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
ZNF441	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54866
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.057628
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3695
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.763
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
PMC7572916-mmc5.xlsx-1_Prevalence-RGS_PITX2	Rummagene Transcription Factor Associations 2026	1.0	null
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19078
EYA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91784
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9575
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.626113
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59085
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
SLC1A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9803
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12654
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
ubiquitously	GeneRIF Biological Term Annotations	1.0	null
TRAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69222
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A615-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67345
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.59419
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39932
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.63212
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2524
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.498241
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9134
X-linked juvenile retinoschisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
Perturb_17412_KO_Kat7_SRP346205	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CCC5	DepMap CRISPR Gene Dependency	1.0	6.88519
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03702
Craniosynostosis	DisGeNET Gene-Disease Associations	1.0	null
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.537527
NR1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78131
hsa-miR-4436b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-52-7622-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4239
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.51412
hsa-miR-105	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23141
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923372
hsa-miR-1267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-3908	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Striatonigral neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.037566
hsa-miR-4448	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
negative regulation of signaling	GO Biological Process Annotations 2015	1.0	null
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01127
Anterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0822
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24321
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37368
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.133488
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50397
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34445
SLX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8874
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-374a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ETS2_KD_GDS5040_129_human_H441	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66409
SLAIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69929
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76895
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
roles	GeneRIF Biological Term Annotations	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12348
RHBDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29851
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
MAFK	ENCODE Transcription Factor Targets	1.0	null
Right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
COMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88808
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5092
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.45692
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76748
transduction	GeneRIF Biological Term Annotations	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22061
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.8275
LP1	CCLE Cell Line Gene CNV Profiles	1.0	2.26558
LNCAPCLONEFGC	DepMap CRISPR Gene Dependency	1.0	3.16786
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32056
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05607
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94448
ASCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43215
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4836
FKBP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73471
physiological	GeneRIF Biological Term Annotations	1.0	null
TBX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91282
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
taste	GeneRIF Biological Term Annotations	1.0	null
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
RAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64977
Lung adenocarcinoma_LUAD_TCGA-75-7030-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881683
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57224
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.33
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LP-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.12931
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.274895
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0777
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.64946
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.37
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1824
Xylanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918744
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.891
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
Lung squamous cell carcinoma_LUSC_TCGA-85-8287-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
CHP134	DepMap CRISPR Gene Dependency	1.0	4.64062
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28714
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825929
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.87226
PAX3	ChEA Transcription Factor Targets	1.0	null
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62591
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28626
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87266
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
Celiac disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4024
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0975
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24547
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39893
examined	GeneRIF Biological Term Annotations	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26066
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16601
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CHP-100 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.899
PARP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41533
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56861
ETS2_KD_GSE43459_687_human_H441 lung cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
bitter	GeneRIF Biological Term Annotations	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4559
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06491
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
GJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81416
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.822
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43868
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7109
PC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5966
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.848105
VGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67957
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0326
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9837
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6236
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
KLHL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33318
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95193
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.866569
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48258
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47124
Hemolymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.51352
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6668
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84473
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3991
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96044
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SLC31A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70004
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.80127
Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6949
COLO704	CCLE Cell Line Gene CNV Profiles	1.0	1.38019
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
C6orf89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44367
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31055
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.33502
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
ZNF467	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65467
HSFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84704
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4528	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04781
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0531
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51131
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.656
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8469
Blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.97234
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
hsa-miR-4799-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.713
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31248
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8847
abnormal salty taste sensitivity	MGI Mouse Phenotype Associations 2023	1.0	null
C-81 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4655
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5712
MTA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73974
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	74.19
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884596
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8
signal	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8342-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COMMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15553
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1966
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5729
ZNF678	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34909
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A8YN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4341
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues	GeneRIF Biological Term Annotations	1.0	null
MJ	DepMap CRISPR Gene Dependency	1.0	6.91054
Axillary bud meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5354
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2511
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.55055
Mitotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
Cardiofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8608
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Capitate projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.619
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
RGS, subdomain 1	InterPro Predicted Protein Domain Annotations	1.0	null
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
general	GeneRIF Biological Term Annotations	1.0	null
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9215
Morphine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1028
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LIN37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35285
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43096
Neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.99713
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8581
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9949
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
KLE	DepMap CRISPR Gene Dependency	1.0	2.2486
GNA11	Pathway Commons Protein-Protein Interactions	1.0	null
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.026
hsa-miR-570	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GNAQ	Pathway Commons Protein-Protein Interactions	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910386
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DESI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30613
inner CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33136
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1327	DepMap CRISPR Gene Dependency	1.0	2.21815
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.62686
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-7756-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU6	DepMap CRISPR Gene Dependency	1.0	2.02465
Leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intellectual developmental disorder with cardiac arrhythmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
Cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.973
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971825
hsa-miR-527	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.195
FOXJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30651
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.372
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
Septin collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
Kidney Chromophobe_KICH_TCGA-KL-8324-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFCAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27801
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
Sarcoma_SARC_TCGA-DX-A3LY-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal umami taste sensitivity	MGI Mouse Phenotype Associations 2023	1.0	null
nucleoside-triphosphatase regulator activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9925
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
DHX40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22128
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
TC32	CCLE Cell Line Gene CNV Profiles	1.0	1.38771
histamine-gated chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46728
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5146
ZFPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51232
C1QTNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76628
KLF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
ABCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95994
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27757
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
PMC12582692-medi-104-e45093-s001.xlsx-Table_S1-Table_S1_Genetic_instruments_of_plasma_proteins_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
Opportunistic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37262
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25566
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.978
hsa-miR-4727-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.869
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86138
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
GSE230263,GSE230265_6_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8054
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4313
Uveal melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
hsa-miR-361-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
SNU324	CCLE Cell Line Gene CNV Profiles	1.0	1.36527
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4426
p190	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.458433
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58437
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6772
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1408
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37521
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
ABL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3512
NCIH1299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59809
SOX17_01_300	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.16336
Invasive aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
Mitotic septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84531
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7837
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.462
PRRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03932
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100464_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03665
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2349
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.889312
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
CJM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42522
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01492
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.723
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857922
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.681
FOXA1_OE_GDS4957_144_human_LNCaP prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7470-01A-12R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95901
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.994315
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44033
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6847
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7002
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4619
nucleus-vacuole junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1903
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21547
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phellogen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
termination of signal transduction	GO Biological Process Annotations 2015	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2679
PMC5963017__F8	PFOCR Pathway Figure Associations 2023	1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71696
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7038
SNUC1	DepMap CRISPR Gene Dependency	1.0	5.15498
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Aspergillosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
Woronin body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5329
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
Postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.487
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.941388
REPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65866
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.74922
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GNAI2	Pathway Commons Protein-Protein Interactions	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4999
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3764
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0455
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61791
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14813
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08373
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5291
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.72757
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4589
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.425389
METTL21EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6985
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08368
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17772
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5875
hsa-miR-409-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11318
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
NPIPB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31099
Lung adenocarcinoma_LUAD_TCGA-55-8619-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09831
gtpase activator activity	GO Molecular Function Annotations 2015	1.0	null
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514
Retinoschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.7985
Tassel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
OVCAR5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8831
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2678
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26123
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2388
LbetaT2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
stomach	HPA Tissue Protein Expression Profiles	1.0	1.45692
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82067
modulates	GeneRIF Biological Term Annotations	1.0	null
abnormal sweet taste sensitivity	MGI Mouse Phenotype Associations 2023	1.0	null
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35451
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916664
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0595
Systemic vasculitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54919
Telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97547
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50384
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-659	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02554
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Extrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.796
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68674
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882828
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956948
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4262
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
hsa-miR-586	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Brain Lower Grade Glioma_LGG_TCGA-DH-5140-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6495
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF623	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54483
Perturb_16515_KD_Pou2af3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.3279
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26431
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5495
IZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36997
Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.901568
negative regulation of g-protein coupled receptor protein signaling pathway	GO Biological Process Annotations 2015	1.0	null
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9442
ISCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38008
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33954
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88669
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4263	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7455
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27757
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.633
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.678
Postsynaptic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.489
GNA15	Pathway Commons Protein-Protein Interactions	1.0	null
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.934
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4352
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10557
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0633
G protein-coupled receptor heterodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29694
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9286
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827189
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.93908
CHD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36837
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4361
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16409
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.056739
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Acute Myeloid Leukemia_LAML_TCGA-AB-2946-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12465
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
253J-BV cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2721
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.860777
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0706
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1871
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34241
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99115
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2575
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6528
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.043855
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
DU4475	CCLE Cell Line Gene CNV Profiles	1.0	1.82337
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
GATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97155
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00879
MIN-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72482
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
Sarcoma_SARC_TCGA-LI-A67I-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	1.60757
Perturb_16516_KD_Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.699
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
MXI1	ENCODE Transcription Factor Targets	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.84753
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5106
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37495
CHLA90	DepMap CRISPR Gene Dependency	1.0	2.90828
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93308
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10088
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3783
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.847386
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06924
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.930966
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
Bradyopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
MHHES1	CCLE Cell Line Gene CNV Profiles	1.0	1.3376
GNAI1	Pathway Commons Protein-Protein Interactions	1.0	null
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59131
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4900-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
FOXE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18518
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8503
Tail muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
Contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67743
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17591
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40706
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80658
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98082
negative regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
HSC4	DepMap CRISPR Gene Dependency	1.0	2.1194
placenta	HPA Tissue Protein Expression Profiles	1.0	0.872029
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9195
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2764
RPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97466
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13459
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5791
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923372
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
laminin-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9102
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857699
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.778
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0385
hsa-miR-4684-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
alpha,alpha-trehalose-phosphate synthase complex (UDP-forming)	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
RB1_KD_GSE50532_659_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3934
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98484
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69448
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9915
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70325
SNU407	CCLE Cell Line Gene CNV Profiles	1.0	1.64573
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29424
IKZF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02616
hsa-miR-513a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3723
Prostate adenocarcinoma_PRAD_TCGA-VP-A875-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MIEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40394
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56968
ITPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34052
Multiple sclerosis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.23979
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24526
Phospholamban complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.43325
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9778
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854555
CHP212	DepMap CRISPR Gene Dependency	1.0	2.13147
hsa-miR-19b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6319
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.836
C19orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3997
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7121
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
Polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.229
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4652
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
HCC1187	CCLE Cell Line Gene CNV Profiles	1.0	1.84195
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2587
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.523
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22257
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89341
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
PMC5963017__F8	PFOCR Pathway Figure Associations 2024	1.0	null
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0618
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55038
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47655
Mesocorticolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
TMEM141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04239
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
Carcinosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.672
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
JUN	ChEA Transcription Factor Targets	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Rto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0649
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66Y-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
LRIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11967
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1858
JM1	CCLE Cell Line Gene CNV Profiles	1.0	1.34469
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
SMC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24677
Cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.968
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993727
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856767
WM3772F	DepMap CRISPR Gene Dependency	1.0	6.84185
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.2975
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959618
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60578
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7425
hemoglobinopathy	GWASdb SNP-Disease Associations	1.0	0.822323
termination of g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.4164
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34633
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2132
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.204
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
Extrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.668
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890433
hsa-miR-1244	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Retromer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17972
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2323
HG3	DepMap CRISPR Gene Dependency	1.0	4.43024
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.274895
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02422
Sturge-Weber syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Hi-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71337
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72265
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3
non-Hodgkin lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
negative regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
COPS7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43988
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6524
H2AC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12369
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70678
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886788
Sinoatrial node disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73208
Food addiction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
FSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95183
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6886
NB12	COSMIC Cell Line Gene CNV Profiles	1.0	2.12931
Pancreatic acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.09001
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1355	DepMap CRISPR Gene Dependency	1.0	5.86856
SW-1573/S1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
ZNF562	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44809
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6874
Autosomal recessive spinocerebellar ataxia 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
TAL1_01_217	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.70032
BICR10	DepMap CRISPR Gene Dependency	1.0	5.64106
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72689
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.56248
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8944
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6752
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97056
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	2.04561
496100467_FWM_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.50611
c1195	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4076
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48706
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1545
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4009
fungal-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0523
Prostate adenocarcinoma_PRAD_TCGA-HC-7742-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19E-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95203
LBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52327
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61691
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5727
BHY	DepMap CRISPR Gene Dependency	1.0	2.0755
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68375
SET2	DepMap CRISPR Gene Dependency	1.0	4.35539
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5985
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78325
Sarcoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.247
FEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52078
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4495
Ileum smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
ZNF785	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27319
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8669-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1_01_47	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.89417
gtpase regulator activity	GO Molecular Function Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844709
SKRC31	CCLE Cell Line Gene CNV Profiles	1.0	1.44662
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837813
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
hsa-miR-19a	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18244
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
Actin cortical patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909503
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24597
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28714
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4291
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	2.06249
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.5413
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41679
GSE182382_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A5XV-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0989
anemia	GWASdb SNP-Disease Associations	1.0	0.391692
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.050146
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
Familial adult myoclonic epilepsy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
Late endosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.561
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75209
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8397
NAGLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24471
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.228
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02422
Sick sinus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.908
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
GTPase activity	GO Molecular Function Annotations 2025	1.0	null
hsa-miR-4682	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
LP1	DepMap CRISPR Gene Dependency	1.0	5.04563
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3218
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85999
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
GNAI3	Pathway Commons Protein-Protein Interactions	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30477
Lung adenocarcinoma_LUAD_TCGA-50-5944-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF235	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43123
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22942
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.281861
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3171
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42252
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4964-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JVE015	DepMap CRISPR Gene Dependency	1.0	2.74399
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOP92	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62739
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0353
Signal Transduction	Reactome Pathways 2014	1.0	null
Polarisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0898
Brush cell (Tuft cell)_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0136
KS-IMM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8925
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14784
Basolateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZQ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27262
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
Actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.427
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93165
Immunodeficiency 51	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
Cellulose synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
KCTD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91449
HCT116	DepMap CRISPR Gene Dependency	1.0	2.06227
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.1536
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Endocytic patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
FYTTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66816
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825929
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8119
BL2751 (SNW1)	NURSA Protein Complexes	1.0	null
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78149
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7185
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4835
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.065
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65147
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3644
LS123	DepMap CRISPR Gene Dependency	1.0	3.19381
enzyme activator activity	GO Molecular Function Annotations 2015	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5911
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.3146
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
RGS domain	InterPro Predicted Protein Domain Annotations	1.0	null
DIABLO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2478
KYSE270	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48169
NCI-H2052	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.14331
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.1195
TP63	ChEA Transcription Factor Targets	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0974
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43279
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18141
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.47702
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51E-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7125
brl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
Nuclear MIS12/MIND complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.812
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.08592
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0418
HNF4, COUP	MotifMap Predicted Transcription Factor Targets	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09838
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56723
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Systemic mycosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4919
Umbilical smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
GNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93607
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78616
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7115
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1025
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22453
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.82323
hsa-miR-4679	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
SUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43833
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.72227
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1034
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
Medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5609
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6849
HS695T	DepMap CRISPR Gene Dependency	1.0	2.30292
CBF3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
beta-catenin destruction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
Mating projection tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
TSC22D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62066
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.069799
Perforation plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3046
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	2.88556
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6094
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
MED13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47573
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.689
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76436
TP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37498
Prostate adenocarcinoma_PRAD_TCGA-CH-5746-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.167694
ZCCHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21933
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56694
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5335
GSE205540_2_v_0_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Marginal zone lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28752
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2456
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31342
SPO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12058
BACH1	ENCODE Transcription Factor Targets	1.0	null
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80961
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986423
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.438
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75913
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9222
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2283
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
hsa-miR-4691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34589
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4683	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79576
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.082131
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26018
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75984
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93472
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3256
PDCD6IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34597
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04699
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.665
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7228
la96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.081
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.74159
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
KLHL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94564
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	2.15986
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9155
G alpha (q) signalling events	Reactome Pathways 2014	1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0034
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17851
Stress fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.435
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_10_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2071
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00234
GSE62843,GSE64370_0_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal taste sensitivity	MGI Mouse Phenotype Associations 2023	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12906
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0683
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76884
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43476
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6702
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.989
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6709
KMRC3	DepMap CRISPR Gene Dependency	1.0	3.82184
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3317-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal hemoglobin	GWASdb SNP-Phenotype Associations	1.0	0.717572
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55615
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.36501
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00775
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88123
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.484
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12047
PMC7572916-mmc5.xlsx-1000_Genomes-RGS_PITX2	Rummagene Transcription Factor Associations 2026	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9294
hsa-miR-568	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.45692
FAM43B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.451
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7771
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30589
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60359
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7789
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32276
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
LMNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41803
NB1	CCLE Cell Line Gene CNV Profiles	1.0	1.59355
Rectum adenocarcinoma_READ_TCGA-AG-3742-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5655
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38546
CST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85033
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.729
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.184422
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE150	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56782
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5246
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.649
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuron to neuron synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.481
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
Cdc42 GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
TSA cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6895
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842873
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11516
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2071
CASKIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69487
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6656
ZNF689	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1316
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
ZFX_KD_GSE43021_130_human_NOMO1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.20311
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71391
AtT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.097
U2-type catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.886
T3M5	DepMap CRISPR Gene Dependency	1.0	6.18251
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50468
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.976
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
NCIH2009	DepMap CRISPR Gene Dependency	1.0	2.25119
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.031923
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53438
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.54994
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
COS-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17375
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9436
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
implying	GeneRIF Biological Term Annotations	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-62-ZNF648_ZNF648	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-374b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7998
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
dbtrg.05mg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.639
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42755
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5511
RNF187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70543
Cerebrovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19146
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70724
hsa-miR-1322	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
IRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51212
Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.079542
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4073
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89416
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56579
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heroin dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.115133
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
Puncta adhaerentia	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67207
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1527
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-i-Classification_of_camel_SON_basal_genes_-_other_targets_IUPHAR_SON	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.764
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.312
hsa-miR-136	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZNF33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01079
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6879
Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of g-protein coupled receptor protein signaling pathway	GO Biological Process Annotations 2015	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5006-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0989
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09711
Pleated septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
Familial adult myoclonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33278
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0744
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.486
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6965
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858714
Jansen's metaphyseal chondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04293
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.84423
CMTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01934
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
GNA14	Pathway Commons Protein-Protein Interactions	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HG-A2PA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B-cell lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5932
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8826
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7576
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0435
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.157
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
hsa-miR-512-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4295
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.942404
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9394
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.919
Lung adenocarcinoma_LUAD_TCGA-55-7903-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hemolytic anemia	GWASdb SNP-Disease Associations	1.0	0.822323
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TP-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2169
G alpha (q) signalling events	Reactome Pathways 2024	1.0	null
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89918
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8589
DHTKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67471
RMND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16076
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.38
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4464
NCIH2052	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38639
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92905
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859764
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-133a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
bladder	GTEx Tissue Gene Expression Profiles	1.0	1.1024
BTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08804
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55465
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
Gastrin-CREB signalling pathway via PKC and MAPK	Reactome Pathways 2014	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17905
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5413
Lung adenocarcinoma_LUAD_TCGA-86-8278-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.7504
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824583
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4463
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
DTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61969
Multiple synapse bouton, contacting multiple dendrites	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1293
Sarcoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.215
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	1.39542
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72717
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.9
SH3GL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0975
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.05476
hsa-miR-485-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SW48	DepMap CRISPR Gene Dependency	1.0	2.41737
MDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86016
Cell pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.308
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
QGP1	CCLE Cell Line Gene CNV Profiles	1.0	1.64644
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QF-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27615
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.971822
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75133
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
hsa-miR-499-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.037
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76846
abnormal gustatory system physiology	MGI Mouse Phenotype Associations 2023	1.0	null
CAOV-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890212
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.667637
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.1559
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81921
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844517
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.42467
disease	GWASdb SNP-Disease Associations	1.0	0.030106
abnormal bitter taste sensitivity	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-576-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56982
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q4-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24277
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5316
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86474
Exocrine acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
UMR-106 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1298
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3919
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.45692
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.225421
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2198
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2569
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97829
hsa-miR-190b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23779
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921795
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3691
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.041
Signaling by GPCR	Reactome Pathways 2014	1.0	null
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92881
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64871
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36855
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76293
Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5986
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5175
Signaling by GPCR	Reactome Pathways 2024	1.0	null
APMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.248
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14954
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1971
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
Spitzenkorper	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20393
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
NLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51904
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59339
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0802
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
U2AF1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06644
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
NG-108-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45561
ETCC016	DepMap CRISPR Gene Dependency	1.0	2.20853
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.040143
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3581
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of gtpase activity	GO Biological Process Annotations 2015	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.916122
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60441
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
hsa-miR-4753-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24625
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36111
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1292
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5796
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1953
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.10332
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9933
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Striatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2548
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7194
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23141
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
CEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6056
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.918
Brain Lower Grade Glioma_LGG_TCGA-DU-8164-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946581
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13596
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911177
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9856
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
GSE100102_4_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of gtpase activity	GO Biological Process Annotations 2015	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0308
MM127	DepMap CRISPR Gene Dependency	1.0	3.15794
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.193
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6801
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05928
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841423
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE173201_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KPNSI9S	CCLE Cell Line Gene CNV Profiles	1.0	1.59635
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8115
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1896
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
Cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
Huelle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.592
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00057
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8529
TTLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64014
all	GWASdb SNP-Phenotype Associations	1.0	0.031865
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.259
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUW-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	85.8185
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4962-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50243
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4972-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9397
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1024
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44O-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.749
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.93
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.796
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1911
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9767
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52041
UNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75456
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83191
SAP30	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3646	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08017
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02835
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03377
KYM1	DepMap CRISPR Gene Dependency	1.0	4.31586