association	dataset	threshold value	standardized value
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08179
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05592
5447_NADSYN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.510235
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101546_2_v_1_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128333_2_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21502
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28496
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58567
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SOTALOL	DGIdb Drug Targets 2026	1.0	1.65412
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257079
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.21423
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-BCL6_target_genes_in_N1-PEF1_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09066
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19668
2925_FAM50A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.506107
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66252
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
3986_HSPE1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.504724
OTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12204
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112860_9_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197948_2_v_0_atp7b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6795_PRPF38B_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.30951
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7627_S100P_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.583356
DA-19-JA87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205947
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F4_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13596
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01645
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
2622_EMG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515425
AB-84-PK04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212133
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31051
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22842
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-KOPN-8_-_MLL-ENL-Non-spreading_targets_gene_names_1358_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21582
GSE138945,GSE138947_0_v_1_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22626
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18023
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33474
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.793564
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
MB-46-BT89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231867
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF736	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0644
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24722
GSE250534_0_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248858_4_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FE-64-KC49_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268231
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79487
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5302
ZNF557	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56706
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_down-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
5791_NR2E1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.647722
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217309
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157049,GSE157051_6_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
Preribosome	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
PMC5692555-pnas.1708341114.sd04.xlsx-3TFs_no_GATA2-gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30715
RNAse mitochondrial RNA processing (MRP) complex	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202151
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07827
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67569
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44602
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37006
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01621
GSE258991_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12113
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
FUBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02897
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288592
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35097
GSE124471,GSE124488_1_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44166
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43077
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46265
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.835225
10478_ZNF585A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.709777
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71534
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9910_XRN1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.676238
4951_MED28_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.22791
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19022
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68505
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.68745
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16634
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04491
chr18_35968086_TC_T_b38	GTEx eQTL 2025	1.0	1.03033
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-SEM_wt_MLL-Gene_name_1614_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28118
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99761
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08515
PPIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80539
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15108
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72662
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE218060_2_v_6_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60334
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16958
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25131
GSE158834_12_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31644
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14522
GSE233679_6_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PCNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1374
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2398
SKIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31651
GSE217982,GSE217983_2_v_3_hgfac_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9753996-jci-132-160767-s182.xlsx-IRF4_assciated-ABCA7_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16187
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102757_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165560_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4389
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11959
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
OB-06-WW76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262423
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00397
CENPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12943
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60739
MEPCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19329
DCTN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02465
343_ANKRD52_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.801814
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246139
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-600-ZNF174_ZNF174	Rummagene Transcription Factor Associations 2026	1.0	null
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03758
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02341
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02478
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52021
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
8853_TFIP11_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.638418
POP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15294
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S5_Miz-1_KD_gene_exp_chan-Genes_up-regulated_in_Miz-1_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44707
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243063
PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP	Rummagene Transcription Factor Associations 2026	1.0	null
DPYSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14091
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5776
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
QA-50-YO37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221272
PMC4224449-pone.0112193.s009.xlsx-PPI_MODULES_CLEAN_MAP_merg_OUT-Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07867
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE96641_3_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26921
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113952,GSE113953_1_v_0_chtop_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
7516_RPS27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.701522
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66569
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7611259-EMS114661-supplement-Supplementary_Tables.xlsx-ST18-Unnamed_10_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186660_2_v_1_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BTN3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53277
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25034
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00002
ERI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07165
8157_SMC3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.621577
PMC11193738-41467_2024_48647_MOESM8_ESM.xlsx-Data_S5-Data_S5_HNF4A-bound_gene_targets_identified_from_ChIP-Seq_in_hepatic_cells_D8_Hep_and_HepG2_cells_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10394
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195663_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.58896
6652_PPP1R10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.501419
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77991
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
DCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6856
GSE242199_2_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.36555
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
H1-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58966
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11314
GSE242199_2_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
LPCAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40184
CE-15-YU05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220414
KCNK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00439
GE-34-TW62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280674
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271939
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.7019
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40484
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10114
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
6889_PSPH_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.514642
IBUTILIDE	DGIdb Drug Targets 2026	1.0	4.411
DOFETILIDE	DGIdb Drug Targets 2026	1.0	1.89043
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
7569_RRS1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.625376
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11934
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	1.0	null
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.664712
PMC7611259-EMS114661-supplement-Supplementary_Tables.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200237
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51987
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Unnamed_5_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09118
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
7455_RPL27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.541274
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6552_POLR2K_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.673411
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44555
PMC9314667-Table_1.xlsx-Regulons-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33101
GSE166317_2_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17054
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172295_3_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF404	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13758
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06024
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.540982
PCDHB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23506
GSE183271_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S3.xlsx-Table_S3F-Supplemental_Table_S3F_ZFX_binding_pattern_clustering_information_for_genes_with_promoters_bound_by_ZFX_related_to_Figure_2I_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02654
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80245
4593_LIN52_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.513389
PMC9746818-jciinsight-7-152886-s077.pdf-29-ENSG00000159216_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1223
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
4349_PRORP_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.63168
GSE189859,GSE189861_1_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01682
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01756
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE108614,GSE108615_0_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130620_1_v_0_kdm4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.500593
PMC12047497-mmc5.xlsx-Sheet1-GSE20754_WT_VS_TCF1_KO_MEMORY_CD8_TCELL_UP_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06636
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
INA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72567
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
RPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36934
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.518109
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04549
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02544
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258479
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.60201
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180641_0_v_1_zfp503_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GOLGA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5806
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50481
PMC3117129-mp2010119x6.xls-CRS_Hpc-Unnamed_5_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleoli	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-HVC_612_gene_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02648
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-MV4_11_-_MLL-AF4-Non-spreading_targets_gene_names_1985_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20071
GPR25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33755
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05278
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19089
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19043
2291_DNAJC17_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.631827
GSE158834_12_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
3557_GSTCD_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.550438
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
10123_ZIC5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.572075
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
SNRPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91388
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37358
PMC6080909-JEM_20171312_TableS1.xlsx-Each_THP1_Pulldown_Expt_Targets-Unnamed_1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9746818-jciinsight-7-152886-s077.pdf-29-RUNX1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126219_0_v_1_haloperidol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.94719
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12963
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22691
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16749
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10867
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
8594_SUPT16H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.5802
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36091
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10351
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.487871
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1937
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239747_2_v_3_lrp6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
7536_RPS6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.549332
GSE192689_0_v_1_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
QUINIDINE	DGIdb Drug Targets 2026	1.0	1.26029
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62894
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00666
GSE192362_1_v_0_erastin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31075
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11359
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.596457
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null