association dataset threshold value standardized value protein ubiquitination GO Biological Process Annotations 2023 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBC Pathway Commons Protein-Protein Interactions 1.0 null mantle zone of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29899 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.73991 GTEX-WXYG-0926-SM-3NB2O GTEx Tissue Sample Gene Expression Profiles 1.0 1.08566 UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Postsubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03096 RNF19B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5644 TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Koelliker-Fuse subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21879 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51117 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null c2c12 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.872754 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44568 Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUO-01A-12R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.8757 STAT5A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-2426-SM-3GILL GTEx Tissue Sample Gene Expression Profiles 1.0 0.893319 MEL270 DepMap CRISPR Gene Dependency 1.0 2.22677 RB1_KD_GSE50532_591_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null TE159T CCLE Cell Line Gene Expression Profiles -1.0 -1.50334 JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59479 HPBALL CCLE Cell Line Gene CNV Profiles -1.0 -2.02952 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.66511 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90272 mantle zone of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57986 intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17233 TCF3 ENCODE Transcription Factor Targets 1.0 null Crus II, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.974031 SRF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraterete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13999 metabolic process GO Biological Process Annotations 2015 1.0 null POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null GSE123372,GSE123373_1_v_2_mecp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Zfp809 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 49.6865 H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.604 TMED9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85557 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11386 H3K36me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55566 CADOES1 CCLE Cell Line Gene Expression Profiles -1.0 -2.67712 Her2_OE_GSE43730_683_human_MCF10A cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.587418 GTEX-VUSG-2226-SM-4KKZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.47003 interpeduncular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37501 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.52858 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22022 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.919282 GABPA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.891798 496100532_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 6.22305 FHIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29821 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE193999,GSE194000_1_v_0_atf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null DNAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94586 NCIH660 CCLE Cell Line Gene Expression Profiles -1.0 -1.90631 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.72533 Vdr JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.2261 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lobule II Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0642 Prostate adenocarcinoma_PRAD_TCGA-J4-A67T-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.2166 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00318 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null CL14 CCLE Cell Line Gene CNV Profiles -1.0 -1.34135 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13379 AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40448 PBX3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE199255,GSE199356_6_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24061 MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Zinc finger, SIAH-type InterPro Predicted Protein Domain Annotations 1.0 null H4C11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85171 CNOT3-19339689-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null RBPJ ChEA Transcription Factor Targets 1.0 null GTEX-XMK1-1126-SM-4IHJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.828957 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.77923 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06811 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.42666 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44568 r7 part of spinal trigeminal nucleus, interpolar part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03096 r7 part of the nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 4.42646 OVKATE CCLE Cell Line Gene CNV Profiles 1.0 1.42795 Retrosplenial area, dorsal part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56336 ARID3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-1826-SM-4BOOJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.979266 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Creb3l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.766 MYC_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2 ENCODE Transcription Factor Targets 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2383 HEATR5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19151 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38509 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.837216 CHP134 DepMap CRISPR Gene Dependency 1.0 2.63158 WM1799 CCLE Cell Line Gene Expression Profiles -1.0 -1.45223 U87MG CCLE Cell Line Gene CNV Profiles -1.0 -1.48576 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02775 Inferior frontal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.553 FOXM1 ENCODE Transcription Factor Targets 1.0 null TCF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZSCAN16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15186 A704 CCLE Cell Line Gene CNV Profiles 1.0 1.56378 NCI-H650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18672 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847236 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.86817 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2897-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hepatomegaly CTD Gene-Disease Associations 1.0 1.07022 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTMR12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75577 TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PBX3 ENCODE Transcription Factor Targets 1.0 null 496100407_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.56695 H3K36me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2383 H3K79me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.4957 Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREB1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null ENHO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81647 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PXYLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07376 CTCF_WI38_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAL33 CCLE Cell Line Gene CNV Profiles 1.0 1.4968 MAFK ENCODE Transcription Factor Targets 1.0 null H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.906 Retrosplenial area, lateral agranular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15369 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.28368 seminiferous tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.696989 outer CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03757 NCIH2004RT DepMap CRISPR Gene Dependency 1.0 2.77832 H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CH157MN DepMap CRISPR Gene Dependency 1.0 2.04275 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBE2D2 Pathway Commons Protein-Protein Interactions 1.0 null Detroit-562 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.768 RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.09343 Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COLO205 DepMap CRISPR Gene Dependency 1.0 2.66673 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5727 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937489 Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobules IV-V, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03549 NFKB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03179 LYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29617 FARAGE DepMap CRISPR Gene Dependency 1.0 4.8308 JHOM2B CCLE Cell Line Gene CNV Profiles -1.0 -1.90129 H3K36me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null breast GTEx Tissue Gene Expression Profiles 1.0 1.81356 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KP3 CCLE Cell Line Gene CNV Profiles 1.0 1.51652 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06253 protein modification by small protein conjugation GO Biological Process Annotations 2023 1.0 null CHLA57 DepMap CRISPR Gene Dependency 1.0 2.41679 GATA3-21867929-CD8-MOUSE ChEA Transcription Factor Targets 2022 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.831126 Ventral posterolateral nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38065 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.08564 NCI-H810 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11554 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3 ENCODE Transcription Factor Targets 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.960293 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.937 Cerebrovascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.273 MYC_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null zona incerta Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871034 HSPA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69775 GSE123502,GSE123504_1_v_0_chd4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GATA3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WM88 CCLE Cell Line Gene Expression Profiles -1.0 -1.76521 DMS-114 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostatic Diseases CTD Gene-Disease Associations 1.0 1.1136 Posterior parietal association areas, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71833 BCL3_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HSC39 DepMap CRISPR Gene Dependency 1.0 2.37583 ANTKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47012 ZBTB33_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04692 Nucleus of the lateral lemniscus, horizontal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07798 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 CCLE Cell Line Gene CNV Profiles 1.0 1.70252 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052424 Hypertrophy CTD Gene-Disease Associations 1.0 1.39646 CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-TKQ1-0008-SM-4DXSO GTEx Tissue Sample Gene Expression Profiles 1.0 1.06424 TEAD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r7Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03226 H3K36me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29259 Magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66954 H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39216 POLR2AphosphoS5_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZBTB33_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901649 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2383 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null E2F4-21247883-LYMPHOBLASTOID-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZG-0001-SM-47JYF GTEx Tissue Sample Gene Expression Profiles 1.0 1.06591 ACLY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37287 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bone marrow TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Anteromedial visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.04668 PPP6R2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17179 Liver Diseases CTD Gene-Disease Associations 1.0 1.17464 HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00905 FBXW5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.152 temporotympanic muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17092 GTF2F1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null FAM110A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85716 POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1898 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10714 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.99971 NFYA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIC_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06119 CYREN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89022 GR MotifMap Predicted Transcription Factor Targets 1.0 null COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.968657 Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81M-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4512-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU5F1-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null YTHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42438 Lobule II, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23234 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.870505 UM-UC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.901649 Prostate adenocarcinoma_PRAD_TCGA-CH-5745-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null EGR1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.097218 Perinuclear theca COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.227 ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3669 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.840405 Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.7586 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08982 H3K36me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Puberty, Precocious CTD Gene-Disease Associations 1.0 1.04501 transferase activity GO Molecular Function Annotations 2015 1.0 null GTEX-WFG8-0001-SM-4LVN8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.892371 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.906703 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100390_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33177 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein metabolic process GO Biological Process Annotations 2015 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17358 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25364 JHOS4 CCLE Cell Line Gene CNV Profiles -1.0 -1.33774 Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GARIN5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33132 r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01436 CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 2.08874 periventricular stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65937 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3186 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.623168 POLR2A_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UCMA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89114 developmental process GO Biological Process Annotations 2015 1.0 null ventral striatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08037 subthalamic nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64531 Lung squamous cell carcinoma_LUSC_TCGA-56-A4BY-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055367 SIN3A ENCODE Transcription Factor Targets 1.0 null RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100629_HIP_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.16749 POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTC642 DepMap CRISPR Gene Dependency 1.0 2.03825 YY1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null cellular protein modification process GO Biological Process Annotations 2015 1.0 null Primary somatosensory area, trunk Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30371 EKVX Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00905 MOLT16 CCLE Cell Line Gene Expression Profiles -1.0 -1.4901 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.55431 CAKI2 CCLE Cell Line Gene CNV Profiles 1.0 1.46807 TBP ChEA Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.16064 mRNA_MYC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835822 GSE183994_3_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Primary somatosensory area, lower limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.75872 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.96674 secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.195639 mantle zone of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0642 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUZC-1026-SM-4BOPY GTEx Tissue Sample Gene Expression Profiles 1.0 0.983943 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.6009 SIX5 ENCODE Transcription Factor Targets 1.0 null NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00905 TAF1_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02262 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANKS6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.32524 NR4A2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8326 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH23 CCLE Cell Line Gene Expression Profiles 1.0 1.79551 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1 Rummagene Transcription Factor Associations 2026 1.0 null protein modification process GO Biological Process Annotations 2015 1.0 null PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44993 NCI-H1417 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Tricuspid atresia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.222 PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_Name_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null GSE196671_5_v_0_obox4_mouse RummaGEO Gene Perturbation Signatures -1.0 null dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12043 Retrosplenial area, lateral agranular part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.16665 OE33 DepMap CRISPR Gene Dependency 1.0 2.03414 CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.172626 SARS-CoV_0Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.23871 HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior occipital gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.901062 EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_16494_KD_RBM39_SRP301121 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.7685 Parasubthalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74036 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WL46-0011-R7A-SM-3LK7X GTEx Tissue Sample Gene Expression Profiles 1.0 1.00878 posteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27686 SIMA CCLE Cell Line Gene Expression Profiles -1.0 -1.50996 GSE211286_4_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03484 TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51064 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9554 PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null SRF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.935083 forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.313683 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90272 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CORL24 CCLE Cell Line Gene CNV Profiles -1.0 -1.40803 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847236 superficial stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27823 HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null Nr1h3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.419 PMC12005766-ADVS-12-2413120-s003.xlsx-VENN1-Table_S6_related_to_Figure_S6D_List_of_overlapping_DEGs_with_the_E3_or_DUB_gene_set_from_the_iUUCD_2_0_database_ZUP1 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC31A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23271 NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9209 SRF ENCODE Transcription Factor Targets 1.0 null TTC709 DepMap CRISPR Gene Dependency 1.0 2.61135 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.897306 CREB1 ENCODE Transcription Factor Targets 1.0 null EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null Spermatogenic failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.6 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39712 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13379 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70959 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Male infertility due to globozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.702 GTEX-U4B1-0726-SM-4DXUA GTEx Tissue Sample Gene Expression Profiles 1.0 0.928585 mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15007 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72743 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q8-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26616 MAX_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AARS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50495 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.5431 PYCR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01503 GABRQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99516 Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14938 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of PSPa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.58089 NCIH716 CCLE Cell Line Gene CNV Profiles 1.0 1.41915 GP5D COSMIC Cell Line Gene Mutation Profiles 1.0 null TRAF-like InterPro Predicted Protein Domain Annotations 1.0 null Right atrial isomerism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.406 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.8608 Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08437 SP1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2814 CCLE Cell Line Gene Expression Profiles 1.0 2.30273 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.55977 BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.59532 496100504_TCx_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.01816 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052423 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.76129 CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00905 RT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.78096 H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SAP30 ENCODE Transcription Factor Targets 1.0 null POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.53017 GTEX-X5EB-0004-SM-46MWA GTEx Tissue Sample Gene Expression Profiles 1.0 0.82474 Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null superficial stratum of PHyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.36481 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07518 NFYA_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.8718 r1 part of vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91828 ASPC1 DepMap CRISPR Gene Dependency 1.0 2.34879 H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F1-26619117-HEPATOCYTES-MOUSE-LIVER ChEA Transcription Factor Targets 2022 1.0 null H3K36me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Supplemental somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82986 HCC827GR5 CCLE Cell Line Gene Expression Profiles 1.0 1.4917 HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 TBP-23326641-C3H10T1-2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BCL3 ENCODE Transcription Factor Targets 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HER2_OE_GDS4763_331_human_MCF10A - immortalized breast epithelial cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0299 layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.84197 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11758 Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28008 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3561 Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0468 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15704 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me2_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KAT2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.449 Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0642 ubiquitin-protein transferase activity GO Molecular Function Annotations 2015 1.0 null GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 1.11756 Lung adenocarcinoma_LUAD_TCGA-55-A48X-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, trunk, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35228 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12989 496100396_HIP_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.01695 Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17092 NB4 DepMap CRISPR Gene Dependency 1.0 2.20358 LCLC97TM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.57633 spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.184448 Sarcoma_SARC_TCGA-3B-A9HJ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARS-CoV MA15_Day4-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.38444 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CORL24 CCLE Cell Line Gene Expression Profiles -1.0 -1.72428 TCCPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.40965 Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH2227 CCLE Cell Line Gene Expression Profiles -1.0 -1.52653 Gonocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.196 POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.18395 Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.888 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.98339 arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22443 NANOG ChEA Transcription Factor Targets 1.0 null ELK4 ENCODE Transcription Factor Targets 1.0 null GTEX-SN8G-0226-SM-4DM6B GTEx Tissue Sample Gene Expression Profiles 1.0 0.89006 USF2 ENCODE Transcription Factor Targets 1.0 null POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9574515-mmc2.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular developmental process GO Biological Process Annotations 2015 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-407 COSMIC Cell Line Gene Mutation Profiles 1.0 null HNF4G_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KAT2A ENCODE Transcription Factor Targets 1.0 null USF2 JASPAR Predicted Transcription Factor Targets 1.0 null H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-HS-A5N9-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD4_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null uterus GTEx Tissue Gene Expression Profiles -1.0 -0.849489 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15551 PAX5_OE_GDS4978_548_human_L428-PAX5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GABPA_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.97853 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1817 POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell differentiation GO Biological Process Annotations 2015 1.0 null LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null YAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40189 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17499 GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles 1.0 0.831558 Testis BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.58124 Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112860_3_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null BCL11A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7848 multicellular organismal reproductive process GO Biological Process Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100657_FWM_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.62678 H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8755441-mmc3.xlsx-IRF7-Up-stat1-hela_IRF7 Rummagene Transcription Factor Associations 2026 1.0 null HEC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54739 placenta HPA Tissue Protein Expression Profiles 1.0 1.3325 GSE122425_1_v_0_nsun2_human RummaGEO Gene Perturbation Signatures -1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-110-PROP1_PROP1 Rummagene Transcription Factor Associations 2026 1.0 null GSE102598_1_v_2_nmda_mouse RummaGEO Drug Perturbation Signatures -1.0 null mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11549 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95885 ARHGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55757 Retrosplenial area, dorsal part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62276 H3K36me3_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.73836 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.2989 SKG-IIIA COSMIC Cell Line Gene Mutation Profiles 1.0 null GABPA_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02238 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer II of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.78193 Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03612 H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATF3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100653_PCx_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15332 HDAC6 ENCODE Transcription Factor Targets 1.0 null oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06878 intermediate stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04402 E2F4_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8508-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_7205_KD_U2AF1a/U2AF1b_ERP006200 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.34255 organelle LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-T5JW-0003-SM-3NMAD GTEx Tissue Sample Gene Expression Profiles 1.0 0.844078 Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null transition metal ion binding GO Molecular Function Annotations 2015 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC3 DepMap CRISPR Gene Dependency 1.0 4.64891 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RELA_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02129 Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.964 HMGB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.943 CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3ac_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ubiquitin-like protein transferase activity GO Molecular Function Annotations 2015 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null PECAPJ41CLONED2 CCLE Cell Line Gene Expression Profiles 1.0 1.80823 HCC1143 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.976387 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72963 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.75839 GSE181517_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures 1.0 null superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21609 nucleus of Darkschewitsch, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.7383 H3K79me2_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null VMRCLCD DepMap CRISPR Gene Dependency 1.0 3.13245 periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26553 H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lobules IV-V, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32232 Subthalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71672 H4C16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93741 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null subcallosal cingulate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.935803 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25979 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058516 HCC70 CCLE Cell Line Gene CNV Profiles 1.0 1.35798 TAF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X1-01A-12R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08121 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24994 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null FTCD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71641 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23983 HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22854 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93521 CH157MN CCLE Cell Line Gene Expression Profiles 1.0 1.37044 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.05963 TFAP2E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6281 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCC26 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZBTB33_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ELK1 ENCODE Transcription Factor Targets 1.0 null Anterodorsal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73749 Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.889226 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GMPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85234 posteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43601 H3K36me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.188146 LN428 CCLE Cell Line Gene Expression Profiles 1.0 2.02036 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-A53B-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KBG syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.257 HMEL CCLE Cell Line Gene Expression Profiles 1.0 3.40794 NCIH2405 CCLE Cell Line Gene Expression Profiles -1.0 -2.22678 ZMIZ1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POLR2AphosphoS5_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00302 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE130246_1_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-RNOR-1426-SM-48FDJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.842716 nucleus coeruleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.885498 RARG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.1073 nucleus GO Cellular Component Annotations 2015 1.0 null GSE162575,GSE162609_3_v_2_tfe3_human RummaGEO Gene Perturbation Signatures -1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13237 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0294 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09862 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DEL CCLE Cell Line Gene Expression Profiles -1.0 -1.72143 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles 1.0 0.907828 cell part GO Cellular Component Annotations 2015 1.0 null PML ENCODE Transcription Factor Targets 1.0 null Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04839 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null shell of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04163 Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8817 male gamete generation GO Biological Process Annotations 2015 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.22927 Prostate adenocarcinoma_PRAD_TCGA-V1-A8ML-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05895 GABPA_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H630 COSMIC Cell Line Gene Mutation Profiles 1.0 null superficial stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21472 membrane LOCATE Predicted Protein Localization Annotations 1.0 null AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14938 MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48058 Prostate adenocarcinoma_PRAD_TCGA-KK-A6DY-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC9A3_KO_GDS3323_495_mouse_colon GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36807 SCC4 DepMap CRISPR Gene Dependency 1.0 5.572 H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC Rummagene Transcription Factor Associations 2026 1.0 null Anemia CTD Gene-Disease Associations 1.0 1.01025 NFIC ENCODE Transcription Factor Targets 1.0 null para-abducens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00866 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28024 POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.9443 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8121 Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.21322 RARB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.146 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911303 MYC-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Zinc finger, RING-type, conserved site InterPro Predicted Protein Domain Annotations 1.0 null TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9075 CREB1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UMRC6 CCLE Cell Line Gene Expression Profiles 1.0 2.03535 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null OCIMY7 CCLE Cell Line Gene CNV Profiles -1.0 -1.41967 STAT1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TMED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62243 limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.249006 Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dentate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60971 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE110248_1_v_6_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10798 kidney GTEx Tissue Gene Expression Profiles 1.0 0.99224 OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06253 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04323 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.179 GTEX-SNMC-0926-SM-4DM5U GTEx Tissue Sample Gene Expression Profiles 1.0 1.24326 Heart conduction disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.888 REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HCC827 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835822 r2 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9643 GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.96794 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F4-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ubiquitin-like protein ligase activity GO Molecular Function Annotations 2023 1.0 null H3K27ac_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MIA PACA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90272 Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, mouth, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13389 r8 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33342 496100365_HIP_probable Alzheimer's disease_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.59532 GTEX-RM2N-0926-SM-48FD1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.920356 ventral entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.58089 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.05198 SETD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32074 Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LN215 CCLE Cell Line Gene Expression Profiles 1.0 1.46446 RAB3A_Mutation - D77G point mutation_GDS2482_702_mouse_Cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null Gfi1b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.0318 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null DCAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46887 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.865246 TCF7L2 ENCODE Transcription Factor Targets 1.0 null GTEX-UJHI-1126-SM-4IHLN GTEx Tissue Sample Gene Expression Profiles 1.0 0.84265 Fatty Liver CTD Gene-Disease Associations 1.0 1.37418 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.16774 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IRF1 ENCODE Transcription Factor Targets 1.0 null SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Perturb_11432_OE_OC2_SRP122890 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.32777 GTEX-TML8-0001-SM-3NMAF GTEx Tissue Sample Gene Expression Profiles 1.0 1.31233 ZEB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3065 KMH2 CCLE Cell Line Gene Expression Profiles -1.0 -1.8018 BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gustatory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03685 GSE199606_5_v_4_csf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KNS81 DepMap CRISPR Gene Dependency 1.0 2.24345 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.29688 OPM2 DepMap CRISPR Gene Dependency 1.0 2.26573 Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47316 GSE214382,GSE214383_6_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K36me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5169 H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.05131 GTF2B ENCODE Transcription Factor Targets 1.0 null HS870T CCLE Cell Line Gene Expression Profiles -1.0 -1.69464 BEX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21174 GSE214382,GSE214383_0_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 2.07098 Avian influenza DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.139 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09522 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.909117 PFKL_OE_GDS1980_203_mouse_dermal fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ARID3A ENCODE Transcription Factor Targets 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.77169 GTEX-S4UY-1326-SM-4AD4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.00984 MAX_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67922 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.8084 MAX_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.941225 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42055 lateral (dentate) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56287 intermediate stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5328 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TCF23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6617 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.6593 GTF2B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null parahippocampal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.926332 magnocellular superficial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.36481 HEC50B CCLE Cell Line Gene CNV Profiles 1.0 1.96986 SIAH-type domain InterPro Predicted Protein Domain Annotations 1.0 null BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPD ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T7-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null SNU1077 DepMap CRISPR Gene Dependency 1.0 2.08045 MYC ChEA Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04169 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nkx2-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.8545 upper dorsal perifornical nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00707 VAMP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59693 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07314 NELFE ENCODE Transcription Factor Targets 1.0 null PSS008 DepMap CRISPR Gene Dependency 1.0 3.21635 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40692 ZBTB7A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LNZ308 CCLE Cell Line Gene Expression Profiles 1.0 1.55212 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.49704 Mesothelioma_MESO_TCGA-NQ-A638-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00905 H3K36me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null r2 part of trigeminal sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06616 SIN3A_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE156115_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null APP Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null macromolecule modification GO Biological Process Annotations 2015 1.0 null dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36187 Infralimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08592 GSE211286_4_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1568 COSMIC Cell Line Gene Mutation Profiles 1.0 null ELF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null preoptic region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.913203 CREB1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Orbital area, lateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1879 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TBP_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38259 496100455_FWM_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.15758 REST_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.94505 FOS ENCODE Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23976 TGFBR1_activemutant_291_GSE14523 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.72284 r7 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67322 Posterior parietal association areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12058 PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MAX_WT_TESTES_MAX Rummagene Transcription Factor Associations 2026 1.0 null NFYB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRR19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75418 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32749 MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF3C6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42295 cellular protein metabolic process GO Biological Process Annotations 2015 1.0 null arm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.550106 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.405935 cytoplasm GO Cellular Component Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_860_KO_Tsga8_SRP254760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-SNMC-0826-SM-4DM66 GTEx Tissue Sample Gene Expression Profiles 1.0 0.859 periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38423 peripheral portion of GPi Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.56816 intermediate stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23883 ubiquitin-protein transferase activity GO Molecular Function Annotations 2023 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.55848 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null GSE77007_3_v_1_med23_mouse RummaGEO Gene Perturbation Signatures -1.0 null SKOV3 DepMap CRISPR Gene Dependency 1.0 3.8236 MTA3 ENCODE Transcription Factor Targets 1.0 null ATF3_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCA1_Knock-in_GDS3544_562_mouse_Cerebellum - 12 Weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null midbrain reticular formation Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04793 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Sensory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.859 EWS502 CCLE Cell Line Gene Expression Profiles 1.0 1.65545 GTEX-XGQ4-0426-SM-4AT4I GTEx Tissue Sample Gene Expression Profiles 1.0 0.864516 IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8434-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.015 H3K36me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55C-0826-SM-48FCL GTEx Tissue Sample Gene Expression Profiles 1.0 0.833827 NR2F2 ENCODE Transcription Factor Targets 1.0 null ITPRIPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8571 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40761 OAW42 DepMap CRISPR Gene Dependency 1.0 3.6437 POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null T98G DepMap CRISPR Gene Dependency 1.0 2.42236 ERVK3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50502 ACHN CCLE Cell Line Gene CNV Profiles 1.0 1.7727 GLYR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46262 ETS1 ENCODE Transcription Factor Targets 1.0 null FABP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01692 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null THAP1 ENCODE Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-DX-AB2P-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4G ENCODE Transcription Factor Targets 1.0 null 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.21612 RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Gustatory areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28833 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.924894 PANC0213 CCLE Cell Line Gene CNV Profiles -1.0 -1.54659 r8 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02801 NOS1 DepMap CRISPR Gene Dependency 1.0 5.90637 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Electrocardiogram morphology (amplitude at temporal datapoints) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.769897 SIN3A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5977-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ASCL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.3147 REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NANOG-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CBX3 ENCODE Transcription Factor Targets 1.0 null gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.922123 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRCA1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4127 TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ES-WA7 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.86711 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.70824 Brain disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.273 parvicellular part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96969 ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32224 BFTC-909 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.863529 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP1-21924763-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null protein modification by small protein conjugation GO Biological Process Annotations 2015 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF4 ENCODE Transcription Factor Targets 1.0 null SRF_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCK81 DepMap CRISPR Gene Dependency 1.0 4.39694 COL9A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57669 TMEM44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83848 GSE203308_9_v_3_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TMMY-1226-SM-4DXT6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916925 496100371_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40227 HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.876387 POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PML_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02633 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TestisGermCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.29556 MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZXDC_KD_GDS5070_504_human_U937 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6384 KDELR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21423 HCC1428 CCLE Cell Line Gene Expression Profiles -1.0 -1.61587 GTEX-UPIC-0926-SM-4IHLV GTEx Tissue Sample Gene Expression Profiles 1.0 1.04617 MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOSL2 ENCODE Transcription Factor Targets 1.0 null KMT5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38019 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7384 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CHD2 ENCODE Transcription Factor Targets 1.0 null Peroxisomal importomer complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.375 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.10552 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8757 GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles 1.0 0.904514 Microspike COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.814 RELA_GM10847_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RELA_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.44051 TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1836 DepMap CRISPR Gene Dependency 1.0 2.45574 protein modification by small protein conjugation or removal GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RARB-24833708-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XOTO-0226-SM-4B66H GTEx Tissue Sample Gene Expression Profiles 1.0 0.903067 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC88C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9386 SKRC31 CCLE Cell Line Gene Expression Profiles 1.0 1.76538 GTEX-TKQ1-0126-SM-33HB3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01557 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52141 Prostate adenocarcinoma_PRAD_TCGA-HC-7817-01B-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gamete generation GO Biological Process Annotations 2015 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r5 part of the oral Sp5 subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.408 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYA ENCODE Transcription Factor Targets 1.0 null HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5448 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1622 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PA-TU-8988S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKRC20 CCLE Cell Line Gene Expression Profiles 1.0 1.414 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08121 ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null Primary somatosensory area, trunk, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44163 H3K9me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles 1.0 0.86435 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.848 SRF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JARID1A-20064375-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SDHAF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57387 GTEX-PLZ5-1626-SM-3NB21 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05351 TMEM138 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18894 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null MM485 DepMap CRISPR Gene Dependency 1.0 3.83878 Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.273 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BACH1 ENCODE Transcription Factor Targets 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X585-0002-SM-46MVA GTEx Tissue Sample Gene Expression Profiles 1.0 0.848402 MTA3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.936059 zinc ion binding GO Molecular Function Annotations 2015 1.0 null Anteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57989 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3561 Gigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33993 HELZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55233 H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.94785 GSE235596_0_v_1_pikfyve_mouse RummaGEO Gene Perturbation Signatures -1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052178 MYC-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149264,GSE149267_4_v_5_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.870553 Primary somatosensory area, mouth, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07798 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r1 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65836 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE215086_8_v_6_batf_human RummaGEO Gene Perturbation Signatures 1.0 null Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95732 NCIH2405 CCLE Cell Line Gene CNV Profiles -1.0 -1.44796 intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16328 H3K36me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.95259 SCARB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99134 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00359 OE-33 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.676 KHM-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.847236 MYC_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S33H-1226-SM-4AD69 GTEx Tissue Sample Gene Expression Profiles 1.0 0.97128 NFATC1 ENCODE Transcription Factor Targets 1.0 null SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-A5KL-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null posteromedial visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.06278 Anteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25982 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Zinc finger, TRAF-type InterPro Predicted Protein Domain Annotations 1.0 null TRIM28 ChEA Transcription Factor Targets 1.0 null OC-314 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-8187-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-0011-R7A-SM-4AT5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.04262 Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CR-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null binding GO Molecular Function Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism cellular process GO Biological Process Annotations 2015 1.0 null ChIP_KLF4_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE137177_1_v_0_folic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null PUS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60386 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22707 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31508 NFIC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrosplenial area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27939 H3K4ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2AphosphoS2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.16946 TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SF539 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02522 Acute Myeloid Leukemia_LAML_TCGA-AB-2866-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.51965 Glaucoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.859 Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.316 KDM5A ChEA Transcription Factor Targets 1.0 null POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF468 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24236 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.976335 ZNF384 ENCODE Transcription Factor Targets 1.0 null HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00905 GTEX-Q2AH-0926-SM-48TZK GTEx Tissue Sample Gene Expression Profiles 1.0 0.977972 POU2F2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.091 biological_process GO Biological Process Annotations 2015 1.0 null FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3834 E2F4 ChEA Transcription Factor Targets 1.0 null Perturb_16495_KD_RBM39_SRP301121 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 19.3979 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDM5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40401 EGR1 ENCODE Transcription Factor Targets 1.0 null GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 2.07259 HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE235390_4_v_0_lurbinectedin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.84532 female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057871 BRCA1 ENCODE Transcription Factor Targets 1.0 null KASUMI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.41776 CLOCK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0864 CCNT2 ENCODE Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.8417 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0038 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.25152 Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KNS-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90272 NKX2-4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2023 NCIH82 DepMap CRISPR Gene Dependency 1.0 5.58251 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE233679_5_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null Posterior parietal association areas, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2265 SIN3A_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.94799 NCIH1993 DepMap CRISPR Gene Dependency 1.0 2.53102 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.08482 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.68579 intermediate part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3003 QPCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41321 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.55928 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null heart GTEx Tissue Gene Expression Profiles -1.0 -1.81228 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 0.912996 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hedgehog signaling complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.964 H3K36me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null LHX1_KO_GDS2748_298_mouse_embryonic renal vesicles GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 496100448_TCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.19772 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null SIX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08422 GSE151612_4_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures -1.0 null PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1 Rummagene Transcription Factor Associations 2026 1.0 null FARSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34618 YY1 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.18961 Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31425 anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10333 BECKER CCLE Cell Line Gene CNV Profiles 1.0 1.37338 ATF3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RELA ENCODE Transcription Factor Targets 1.0 null dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCIH1651 CCLE Cell Line Gene CNV Profiles 1.0 1.34753 Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61601 primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.191862 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20935 KARPAS299 CCLE Cell Line Gene CNV Profiles 1.0 2.25999 KIAA1671 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73023 SIN3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PR8(H1N1)_12hour_None_GSE37245 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.8401 SNU349 CCLE Cell Line Gene Expression Profiles 1.0 1.52618 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTLL7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9329 HCC2429 DepMap CRISPR Gene Dependency 1.0 2.26125 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18078 BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3344 NHE3_Deficiency_GDS3323_599_mouse_Colon GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.30649 496100467_FWM_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.34747 Atrophy CTD Gene-Disease Associations 1.0 1.21695 TTC32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89846 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6774-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBC-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10368 BT-474 COSMIC Cell Line Gene Mutation Profiles 1.0 null SIN3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90272 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A541-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsal entopeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12823 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4739-01A-02R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84165 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEKTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02369 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null PML_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07899 Sarcoma_SARC_TCGA-DX-A6YZ-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ChIP_TRIM28_19339689 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null embryoday9.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.878537 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72963 HPAC Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90272 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72743 RASD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37348 MKN45 CCLE Cell Line Gene CNV Profiles -1.0 -1.37596 Zinc finger, RING/FYVE/PHD-type InterPro Predicted Protein Domain Annotations 1.0 null pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.890022 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.01477 HCC1395 DepMap CRISPR Gene Dependency 1.0 2.20531 GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.1666 Atrial fibrillation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.888 TestisSeminiferousTubule BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.12296 CYB5R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18763 Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.26272 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5282 MXI1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.1522 Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LGR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37625 H3K36me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMC18 DepMap CRISPR Gene Dependency 1.0 2.42945 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA ENCODE Transcription Factor Targets 1.0 null OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25285 SPDEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57663 H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061518 H3K79me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 part of descending trigeminal sensory nucleus, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66481 CNOT3-19339689-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null PDP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00675 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08121 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.992468 GSE110178_2_v_6_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.90242 PMC5193459-pone.0168968.s009.xlsx-Dharmacon_OTP_siRNA_Area-Symbol_OTP Rummagene Transcription Factor Associations 2026 1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null MDAMB361 CCLE Cell Line Gene CNV Profiles 1.0 1.65594 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ChIP_NANOG_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835822 MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles 1.0 0.858604 POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100507_FWM_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.30361 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AMO1 DepMap CRISPR Gene Dependency 1.0 5.2741 RUNX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56995 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2354 PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Ensembl_Gene_ID_ZBTB16 Rummagene Transcription Factor Associations 2026 1.0 null TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13925 ATF2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_S7B-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_WT_TESTES_874_GENES_MAX Rummagene Transcription Factor Associations 2026 1.0 null NCIH1105 CCLE Cell Line Gene CNV Profiles -1.0 -1.37738 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.48999 medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11549 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNAI2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5722 SSH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38294 E2F4-21247883-LYMPHOBLASTOID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VMRCRCW CCLE Cell Line Gene CNV Profiles 1.0 1.53492 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02225 FOSL2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null superficial stratum of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39618 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-68-A59I-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C33A DepMap CRISPR Gene Dependency 1.0 2.11012 WWC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78146 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM28-19339689-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_7329_OE_MOV10_SRP120600 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.11569 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1208 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68666 CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33148 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.88361 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7797 STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.14896 periventricular stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07407 Acute Myeloid Leukemia_LAML_TCGA-AB-2868-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.27151 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NANOG-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CNOT3 ChEA Transcription Factor Targets 1.0 null BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POTEE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19958 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835822 Rectal Mucosa Donor 31 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.942003 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66291 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.07418 subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01778 PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2836 CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.885099 GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles 1.0 0.956068 MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal segment of globus pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60382 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-UJMC-1226-SM-4IHLI GTEx Tissue Sample Gene Expression Profiles 1.0 0.871328 NBPF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75641 CREB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RELA_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MOLM13 DepMap CRISPR Gene Dependency 1.0 3.85435 GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles 1.0 0.859491 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.4925 FOS_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 2.27428 Perinuclear region of cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.702 catalytic activity GO Molecular Function Annotations 2015 1.0 null SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.922372 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85406 RELA_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYOD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5348 anterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12536 molecular_function GO Molecular Function Annotations 2015 1.0 null SIN3A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Taenia tecta, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10623 H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE180185_9_v_5_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null MYC_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.837914 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4153-01B-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryoday6.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH446 DepMap CRISPR Gene Dependency 1.0 2.05635 ETS1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Prp19 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.061 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.99657 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.99907 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50J-01A-21R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1201 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9574515-mmc1.xls-THP1_60_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null organic substance metabolic process GO Biological Process Annotations 2015 1.0 null REST ENCODE Transcription Factor Targets 1.0 null lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8963 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE77108_3_v_9_saha_human RummaGEO Drug Perturbation Signatures -1.0 null HS729 CCLE Cell Line Gene Expression Profiles -1.0 -1.45236 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.928159 Primary somatosensory area, lower limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.07252 KLF4-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64531 not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52075 EP300 ENCODE Transcription Factor Targets 1.0 null MYC-19030024-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08121 E2F4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCUM1 DepMap CRISPR Gene Dependency 1.0 2.3845 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null ELK4_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50107 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 Ventral premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43975 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13083 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POU2F2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KLF4 ChEA Transcription Factor Targets 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-SI-A71O-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF4_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.66998 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 2.29049 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE149760_3_v_5_elof1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K36me3_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.868419 WHRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99069 Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 0.892304 Lung squamous cell carcinoma_LUSC_TCGA-60-2725-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE242083,GSE242098_2_v_5_med1_human RummaGEO Gene Perturbation Signatures -1.0 null Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZKSCAN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33004 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37355 DDT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03755 NELFE_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10236 Lung adenocarcinoma_LUAD_TCGA-38-4632-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SUCS-0002-SM-3NMAJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.24627 ESRRA ENCODE Transcription Factor Targets 1.0 null TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35869 Brain Lower Grade Glioma_LGG_TCGA-HT-7879-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100438_PCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.00956 finger TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.607722 r8 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.88675 GTEX-S7SE-0226-SM-2XCD4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.922745 FOXP1-21924763-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-REY6-1426-SM-48FDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.02637 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE196104,GSE196106_2_v_0_vsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.03876 SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH810 CCLE Cell Line Gene CNV Profiles 1.0 2.88415 USF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22182 GSE218907_3_v_2_opa1_mouse RummaGEO Gene Perturbation Signatures 1.0 null r2 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40147 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.914664 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15434 ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX3 ENCODE Transcription Factor Targets 1.0 null periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.56835 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.39139 H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFG8-2326-SM-3GILF GTEx Tissue Sample Gene Expression Profiles 1.0 0.910464 corpus callosum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.8737 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16296 TCF12 ENCODE Transcription Factor Targets 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70644 UMUC9 DepMap CRISPR Gene Dependency 1.0 3.17955 upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.41599 Lung squamous cell carcinoma_LUSC_TCGA-85-8049-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU668 DepMap CRISPR Gene Dependency 1.0 3.22253 GSE199606_5_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures 1.0 null POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lymphoid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.523 JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spermatogenic failure 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.703 ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.39645 496100592_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.17907 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gustatory areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00144 PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PD-70-VS77_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.277294 H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.3693 inferior occipital gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.904559 KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.17886 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1 Rummagene Transcription Factor Associations 2026 1.0 null outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0049 ELF1 ENCODE Transcription Factor Targets 1.0 null CHD2_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7L2_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.08252 r7 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62247 ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MORF4L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82037 CAL148 CCLE Cell Line Gene CNV Profiles 1.0 1.39448 RNF185 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85169 NFYB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937489 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar nuclei of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40974 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.931941 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830208 H3118 DepMap CRISPR Gene Dependency 1.0 2.00955 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R3RS-0726-SM-3GIJR GTEx Tissue Sample Gene Expression Profiles 1.0 0.920255 layer 4 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14149 H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CENPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29852 PML_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TTLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03314 TE5 CCLE Cell Line Gene CNV Profiles 1.0 1.6476 posterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11665 RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.151 Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adams-Oliver syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S341-0126-SM-4AD64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41085 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.83453 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null open-angle glaucoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.859 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3278 HA1E DepMap CRISPR Gene Dependency 1.0 2.73713 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GSE131649_2_v_0_hemin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.036519 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.08121 SNX33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93692 paracentral lobule, posterior part, left, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.94694 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.89785 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null HK2 CCLE Cell Line Gene Expression Profiles 1.0 1.60298 GSE165560_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF770 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9849 TLE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33306 Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063232 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCO2 DepMap CRISPR Gene Dependency 1.0 2.12247 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null L33 DepMap CRISPR Gene Dependency 1.0 2.1861 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ovary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.04942 r6 part of spinal trigeminal nucleus, pars oralis Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68618 H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE229580_2_v_3_creb1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles 1.0 0.836876 single-organism developmental process GO Biological Process Annotations 2015 1.0 null NFYB ENCODE Transcription Factor Targets 1.0 null GTEX-VUSG-2326-SM-4KL1U GTEx Tissue Sample Gene Expression Profiles 1.0 1.07807 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.888 NCIH2066 CCLE Cell Line Gene CNV Profiles -1.0 -2.70788 CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80429 Brain Lower Grade Glioma_LGG_TCGA-WH-A86K-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Interposed nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04254 H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.943995 Ptf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 53.044 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SF-0001-SM-3K2BE GTEx Tissue Sample Gene Expression Profiles 1.0 1.25686 medial part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12823 H3K4me1_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MALME3M CCLE Cell Line Gene CNV Profiles 1.0 2.66354 JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0605 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.76138 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mRNA_AES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ATF3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null OCIAML5 CCLE Cell Line Gene Expression Profiles -1.0 -1.69051 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.97159 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.51527 muscle GTEx Tissue Gene Expression Profiles -1.0 -0.935007 medial geniculate complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05079 NCIH1048 CCLE Cell Line Gene CNV Profiles -1.0 -2.20207 magnocellular diagonal band nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.149 FOXP1 ChEA Transcription Factor Targets 1.0 null IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.67801 HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Eye disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.859 GTEX-NFK9-2026-SM-3LK5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.991789 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.201 superficial stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40147 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WO-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.782 t69-brown-adipose_male_1w MoTrPAC Rat Endurance Exercise Training -1.0 -1.71971 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45236 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MG-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-719 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13241 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_FEM1B_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-8115-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OV7 DepMap CRISPR Gene Dependency 1.0 3.10352 SCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.80168 Lung squamous cell carcinoma_LUSC_TCGA-18-3415-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31025 NCIH508 CCLE Cell Line Gene Expression Profiles 1.0 1.38215 Primary somatosensory area, nose Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58059 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.6505 POLR2A_GM10847_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tretinoin_homo sapiens_gpl6244_gds4180 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hand TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.606916 GTEX-QVJO-0526-SM-447CE GTEx Tissue Sample Gene Expression Profiles 1.0 0.94023 ADAMTS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64832 GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 1.07962 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2584 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31407 Prostate adenocarcinoma_PRAD_TCGA-EJ-7218-01B-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.8022 NANOG-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A77J-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ubiquitin protein ligase activity GO Molecular Function Annotations 2023 1.0 null PEX16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55428 occipito-temporal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14763 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 2.17404 YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null C32 DepMap CRISPR Gene Dependency 1.0 2.61426 Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TARBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57594 PMC9574515-mmc2.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49787 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-1126-SM-48U1P GTEx Tissue Sample Gene Expression Profiles 1.0 0.95422 P2RX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7402 lateral hypothalamic area, tuberal part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30352 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null INSM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.5417 H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferior occipital gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.85079 MZ in retrosplenial cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0103 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZXDC1_KD_GSE45417_686_human_U937 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.07518 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null lateral part of MM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48332 KMS27 CCLE Cell Line Gene CNV Profiles -1.0 -2.76294 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -2.41698 SH3GL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0975 MAFF ENCODE Transcription Factor Targets 1.0 null cation binding GO Molecular Function Annotations 2015 1.0 null shell of SCH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27751 JARID1A-20064375-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null H3K36me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.95885 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF354A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7459 Nr5a1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.2966 SRF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.10073 K2 COSMIC Cell Line Gene Mutation Profiles 1.0 null HDAC2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LU-165 COSMIC Cell Line Gene Mutation Profiles 1.0 null TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0381 NR1D1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0237 IZ in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05604 reticulotegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.84385 RNF182 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38815 zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.20285 SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.25311 NANOG-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null NDUFB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40595 MYBL2 ENCODE Transcription Factor Targets 1.0 null GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.05246 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC39A13_Deficiency_GDS3485_570_mouse_Chondrocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5228 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone marrow HPA Tissue Protein Expression Profiles 1.0 3.27095 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LTBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28221 Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VMRCLCD CCLE Cell Line Gene Expression Profiles 1.0 1.46901 ZNF76 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7625 RCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87317 KPNRTBM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.79226 Central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.273 MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATG2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36048 GTEX-SNMC-1426-SM-2XCFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.01271 Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A89H-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Retrosplenial area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51563 heart muscle HPA Tissue Protein Expression Profiles 1.0 1.3325 ZBTB33_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.55151 GSE195663_7_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4901 Prostate adenocarcinoma_PRAD_TCGA-XJ-A83H-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.921285 BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835822 Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TT2609C02 CCLE Cell Line Gene CNV Profiles -1.0 -1.56604 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93813 layer 4 of CCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14741 Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3329-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.22146 male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.253578 OC316 DepMap CRISPR Gene Dependency 1.0 3.20016 P63-20808887-KERATINOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-XPVG-2526-SM-4B66D GTEx Tissue Sample Gene Expression Profiles 1.0 1.05907 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21864 Perturb_17268_KO_Sox30_SRP139811 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.721441 HCC364 CCLE Cell Line Gene CNV Profiles -1.0 -1.66628 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05175 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.03237 CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5878 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.6858 TMEM230 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.39134 medial part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58128 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5045-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBP-23326641-C3H10T1-2-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20P-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Lung adenocarcinoma_LUAD_TCGA-44-6776-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32633 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.9171 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRICKLE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62038 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 H3K36me3_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47843 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5372 GTEX-XGQ4-0004-SM-4AT5S GTEx Tissue Sample Gene Expression Profiles 1.0 1.21224 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22328 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4869-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vas deferens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.822 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null metal ion binding GO Molecular Function Annotations 2015 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 0.84955 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Culmen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15752 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52006 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.85956 DPM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65991 GTEX-TKQ1-0326-SM-4DXSM GTEx Tissue Sample Gene Expression Profiles 1.0 1.04275 NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.50983 TMEM231 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42097 TAF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.432991 AMIGO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45537 D425 DepMap CRISPR Gene Dependency 1.0 2.29722 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.60734 outer CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.934193 SMC3 ENCODE Transcription Factor Targets 1.0 null CORL47 DepMap CRISPR Gene Dependency 1.0 3.07189 SKNDZ DepMap CRISPR Gene Dependency 1.0 3.7098 superficial stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66481 Lung squamous cell carcinoma_LUSC_TCGA-77-8150-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMEL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78691 MZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843245 PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null POU2F2_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4663 layer 4 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28024 reproductive process GO Biological Process Annotations 2015 1.0 null KIAA1143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43794 SARS-dORF6_60Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.59985 496100487_HIP_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.17593 PMC12648952-12915_2025_2452_MOESM4_ESM.xlsx-S4c-Pseudobulk_AP2_vs_B57-Unnamed_11_GTF3A Rummagene Transcription Factor Associations 2026 1.0 null NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 esophagus HPA Tissue Protein Expression Profiles 1.0 1.3325 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_WT_TESTES_MAX Rummagene Transcription Factor Associations 2026 1.0 null TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0756 ventral premammillary nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02883 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62573 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null horizontal nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73224 ChIP_NANOG_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Sarcoma_SARC_TCGA-X6-A7WD-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.933892 Cortical amygdalar area, anterior part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17225 MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8834 HS821T CCLE Cell Line Gene CNV Profiles 1.0 1.38489 RHJT DepMap CRISPR Gene Dependency 1.0 3.75967 STUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44342 superficial stratum of r5Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.408 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12135 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2722 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.86741 KASUMI1 CCLE Cell Line Gene CNV Profiles -1.0 -1.77852 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.0827 ATF2 ENCODE Transcription Factor Targets 1.0 null SH3BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59085 Heart disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.888 Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.427 TestisLeydigCell BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.09087 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null Magnocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66215 SP1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 0.847682 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835822 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19617 Septofimbrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08732 Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07536 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RR-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.932038 ZBTB21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40322 PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -1.37376 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5099-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34837 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RMGI CCLE Cell Line Gene Expression Profiles 1.0 1.73687 GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12583 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03934 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NFYA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.933 submammillothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19881 DFCI024 CCLE Cell Line Gene Expression Profiles 1.0 2.24189 HS229T CCLE Cell Line Gene Expression Profiles -1.0 -1.58123 GTEX-T8EM-1226-SM-4DM5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.44745 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27887 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE233679_14_v_15_nicotinamide_human RummaGEO Drug Perturbation Signatures 1.0 null EW8 CCLE Cell Line Gene Expression Profiles 1.0 2.1819 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null lateral superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08511 CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12608 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05234 HCFC1 ENCODE Transcription Factor Targets 1.0 null POU5F1 ChEA Transcription Factor Targets 1.0 null MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESRRA_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Z8-0226-SM-4AD5K GTEx Tissue Sample Gene Expression Profiles 1.0 0.918378 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null single organism reproductive process GO Biological Process Annotations 2015 1.0 null ventromedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.864087 superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82025 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null midline nuclear complex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.876555 pituitary GTEx Tissue Gene Expression Profiles 1.0 1.01426 Vascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.273 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null TIA1_KO_GSE54418_260_mouse_cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles 1.0 0.833116 Lung squamous cell carcinoma_LUSC_TCGA-85-8072-01A-31R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02025 TMEM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.678 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null intracellular organelle GO Cellular Component Annotations 2015 1.0 null GTEX-SJXC-2026-SM-4DM6N GTEx Tissue Sample Gene Expression Profiles 1.0 1.16894 H3K36me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_TUBA1A_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null substantia nigra, reticular part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.968824 cell part LOCATE Predicted Protein Localization Annotations 1.0 null inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04648 E2F6 ENCODE Transcription Factor Targets 1.0 null Liver Neoplasms CTD Gene-Disease Associations 1.0 1.11606 RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_NR0B1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.664809 TRIM28-19339689-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null LCLC103H CCLE Cell Line Gene Expression Profiles -1.0 -2.13626 CHD2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0851 laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04116 Ubiquinone biosynthesis complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.087 ECC4 DepMap CRISPR Gene Dependency 1.0 6.04702 Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PL-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PACADD165 DepMap CRISPR Gene Dependency 1.0 2.24477 Zinc finger, RING-type InterPro Predicted Protein Domain Annotations 1.0 null AEN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49807 POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE255680_2_v_0_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null MPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20856 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null dorsolateral part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03226 CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Flagellate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.278 FEZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.0151 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HUH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.94513 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCI-SNU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ChIP_GCN5_20946988 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.11536 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 0.934113 Ebstein anomaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.149 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.04595 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04908 CREB1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0425 internal granular layer of CbVCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05104 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01480 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.962979 accessory entopeduncular nucleus (post-migratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40113 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210885_5_v_6_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59858 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8CE-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVMANA CCLE Cell Line Gene Expression Profiles 1.0 1.42714 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.00525 PLEKHO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92628 RNF135 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71105 Anteromedial visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.18987 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW403 CCLE Cell Line Gene CNV Profiles 1.0 1.38068 MOLM16 CCLE Cell Line Gene CNV Profiles -1.0 -1.43698 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18275 GSE111102,GSE111105_8_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04722 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RN-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cellular metabolism and vesicular transport regulation CM4AI U2OS Cell Map Protein Localization Assemblies 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5006-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB33_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15551 NCIH2347 CCLE Cell Line Gene CNV Profiles -1.0 -1.60694 FAAP20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4165 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TKQ1-0003-SM-3NMAE GTEx Tissue Sample Gene Expression Profiles 1.0 1.11862 Lung adenocarcinoma_LUAD_TCGA-62-A46Y-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13241 ChIP_CNOT3_19339689 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null STAT5A ENCODE Transcription Factor Targets 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null eGFP-HDAC8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH226 DepMap CRISPR Gene Dependency 1.0 2.10308 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7732-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06119 SLR24 CCLE Cell Line Gene Expression Profiles 1.0 2.4569 PUR1 MotifMap Predicted Transcription Factor Targets 1.0 null fusiform gyrus, left, bank of cos Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.836339 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.25609 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null Dextrocardia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.990005 GTEX-XOTO-0011-R5A-SM-4B657 GTEx Tissue Sample Gene Expression Profiles 1.0 1.42299 GTEX-WL46-0426-SM-3TW8J GTEx Tissue Sample Gene Expression Profiles 1.0 0.945637 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC3702285-cddis2013211x6.pdf-355-ZNF35_ZNF35 Rummagene Transcription Factor Associations 2026 1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32661 MCF10F Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.668325 Lung squamous cell carcinoma_LUSC_TCGA-56-8304-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR1I2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4886 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.888 E2F6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SA1-27219007-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-PVOW-0626-SM-2XCF6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.907495 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.71801 H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FAM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0513 HUPT4 CCLE Cell Line Gene CNV Profiles -1.0 -1.48743 RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2 Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17715 496100381_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08967 Gustatory areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50116 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XPVG-0526-SM-4B65N GTEx Tissue Sample Gene Expression Profiles 1.0 1.10361 HUT78 CCLE Cell Line Gene CNV Profiles -1.0 -1.54318 POLR2AphosphoS2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17383 ONCODG1 CCLE Cell Line Gene CNV Profiles 1.0 2.09732 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null klf5_18983969_embryonic_stem_cell_lof_mouse_gpl1261_gds3509 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.829432 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARS-CoV_84Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.38234 GSE199255,GSE199356_4_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null protein ubiquitination GO Biological Process Annotations 2015 1.0 null dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08908 COV318 CCLE Cell Line Gene Expression Profiles 1.0 1.44119 mRNA_MSC_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SLR25 CCLE Cell Line Gene CNV Profiles 1.0 1.86967 KLF4-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null TestisIntersitial BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.97707 SF172 CCLE Cell Line Gene Expression Profiles 1.0 1.61179 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.3493 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOLM14 DepMap CRISPR Gene Dependency 1.0 2.56115 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81751 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76371 CREB1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, lower limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05458 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null GSE203308_14_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SNU840 DepMap CRISPR Gene Dependency 1.0 2.26851 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.85044 T3M3 DepMap CRISPR Gene Dependency 1.0 3.92476 Townes-Brocks syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.197 periventricular stratum of r2Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96272 Retrosplenial area, lateral agranular part, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81151 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.929401 hnf4a_16714383_e18dot5_liver_lof_mouse_gpl1261_gds1916 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.172321 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.245175 Primary somatosensory area, upper limb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16223 GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_ID_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null BCLAF1 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-WY-A85A-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QDVN-0726-SM-4B64L GTEx Tissue Sample Gene Expression Profiles 1.0 0.826808 ACIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91029 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.75198 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00905 GTF2F1 ENCODE Transcription Factor Targets 1.0 null raphe magnus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1564 Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null placenta BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.38992 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20237 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.86978 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SRF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.78642 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21238 mast cells BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.38051 GTEX-T5JC-1526-SM-4DM68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08529 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null TE5 DepMap CRISPR Gene Dependency 1.0 3.14867 CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_766_mouse_Skin - 0 Day GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE109140_0_v_3_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65258 ChIP_JARID1A_20064375 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LN-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RELA_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.782 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IOMMLEE CCLE Cell Line Gene Expression Profiles 1.0 1.85965 ZBTB32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50521 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HELB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56073 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.66361 Dorsal premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16026 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal muscle HPA Tissue Protein Expression Profiles 1.0 1.3325 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100642_PCx_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.06426 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202310_1_v_0_ube3d_mouse RummaGEO Gene Perturbation Signatures 1.0 null gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.099208 GCIY CCLE Cell Line Gene CNV Profiles 1.0 1.41002 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.97219 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.1603 KE-73-XV62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.49124 GTEX-S4UY-1626-SM-4AD55 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1774 RHOXF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4934 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.0187 cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0431 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate (interpositus) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2027 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.835822 GSE112761,GSE112767_2_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BCL3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A845-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55G-0226-SM-48FEI GTEx Tissue Sample Gene Expression Profiles 1.0 1.18939 superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04006 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.672 intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54241 H3K36me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12864 RCC-JF COSMIC Cell Line Gene Mutation Profiles 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.32571 GTEX-WH7G-0002-SM-4LVN9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23835 Sarcoma_SARC_TCGA-DX-A48K-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryoday7.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.94636 MYC_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7QZ-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anteromedial visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.41395 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.52872 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0406 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4755 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XGQ4-2226-SM-4AT4Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.917405 GOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18984 GTEX-QDVN-0526-SM-48TZ4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.876511 H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null ZBTB33 ENCODE Transcription Factor Targets 1.0 null TCF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19773 Spinal nucleus of the trigeminal, oral part, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16156 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAMSAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07204 r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02644 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.937504 spermatogenesis GO Biological Process Annotations 2015 1.0 null POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32158 PBX3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Urogenital Abnormalities CTD Gene-Disease Associations 1.0 1.32132 Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF713 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39699 LOUCY CCLE Cell Line Gene CNV Profiles -1.0 -2.31447 NFYB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3532 EP300_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 C19orf12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77718 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.847546 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OCT4-18692474-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6608 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71524 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.05982 TFAP2A JASPAR Predicted Transcription Factor Targets 1.0 null RBPJ-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null liver BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.46551 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4604-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VCAP CCLE Cell Line Gene CNV Profiles -1.0 -1.53067 Posterior parietal association areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36927 GTEX-UPK5-0003-SM-3NMDI GTEx Tissue Sample Gene Expression Profiles 1.0 1.06608 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, trunk, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42924 GTEX-T5JW-0426-SM-4DM7M GTEx Tissue Sample Gene Expression Profiles 1.0 1.25601 YAE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5319 substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.889584 SCYL1_knockdown_194_GSE57646 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.15067 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47537 GSE239541_11_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures -1.0 null precentral gyrus, left, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.910707 r1 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39439 CXXC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19571 NCIH1793 CCLE Cell Line Gene CNV Profiles -1.0 -1.41967 Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFATC1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.76371 POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00789 ATF1 ENCODE Transcription Factor Targets 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null Perturb_1324_KD_RBM39_SRP301121 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 10.3941 MEAK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67826 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14853 THAP1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE157904_0_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobules IV-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15885 GTEX-OIZH-0126-SM-2HMIS GTEx Tissue Sample Gene Expression Profiles 1.0 1.31162 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HT144SKINFV1 DepMap CRISPR Gene Dependency 1.0 4.25217 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9471 ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100500_PCx_probable Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.67342 MYC_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.12989 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-1226-SM-4GICG GTEx Tissue Sample Gene Expression Profiles 1.0 1.46604 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80592 GTEX-XPVG-2626-SM-4B669 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19858 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053961 GSE210655_3_v_5_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48844 APP_KO_GDS4414_370_mouse_prefrontal cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IB-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-52-7622-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZEB1 ENCODE Transcription Factor Targets 1.0 null THOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11508 abducens motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07484 GSE157904_3_v_1_doxorubicin_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC10214295-mmc4.xlsx-A_-_Human_Islets_ZBTB16_targets-Gene_Name_ZBTB16 Rummagene Transcription Factor Associations 2026 1.0 null TP63 ChEA Transcription Factor Targets 1.0 null RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38363 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.84136 nucleus of the diagonal band, left, horizontal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.945981 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.7995 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15813 PMC9574515-mmc1.xls-THP1_0_min_GM-CSF-Target_Gene_Symbol_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4801-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null