association	dataset	threshold value	standardized value
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967649
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	2.9864
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5325
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5725
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53384
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32212
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44602
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0679
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.25803
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43415
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65563
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43588
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0801
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24175
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01894
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1764
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961646
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4415
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869379
CLTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37858
Perturb_5050_KO_Pcgf6_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.1766
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.103
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979851
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8449
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2909
TDOTT	DepMap CRISPR Gene Dependency	1.0	3.05483
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50584
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983695
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78376
Late recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.461
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.103
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33617
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.221
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6329
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983695
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11092
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1602
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0763
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13098
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80288
SKN3	DepMap CRISPR Gene Dependency	1.0	3.67988
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.04119
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22333
GSE179002_3_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17594
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.932205
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869379
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915466
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
KM12	DepMap CRISPR Gene Dependency	1.0	2.55942
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1909
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.304
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.13599
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66259
DOID:7061	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.954
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein modification by small protein conjugation	GO Biological Process Annotations 2023	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974437
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21251
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2211
496100537_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18006
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
TBX2-35687133-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5509
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910902
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29146
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9106
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4603
NCIH226	DepMap CRISPR Gene Dependency	1.0	3.21028
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.648
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.73017
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8554
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.987552
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
SUM1315MO2	DepMap CRISPR Gene Dependency	1.0	2.14024
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.94237
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23425
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83187
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55374
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918419
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20407
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21924
Perturb_2837_KD_CDK12_SRP073459	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PLXNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75611
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3459
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12007
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8923
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93817
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4897_KD_U2AF1_SRP160510	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.37181
C75	DepMap CRISPR Gene Dependency	1.0	2.02501
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	302.314
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33697
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29729
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31623
NRDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29573
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26028
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03387
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20379
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58693
GSE198165,GSE198166_5_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7905
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10193
Acute leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76206
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33699
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.0991
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33013
CORL279	DepMap CRISPR Gene Dependency	1.0	2.24723
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04361
TE4	DepMap CRISPR Gene Dependency	1.0	4.62153
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
PABPC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24669
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9163
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06904
WARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27963
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
GSE181749_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0422
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8198
Perturb_5093_KO_Mga_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.8182
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843238
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.8704
homologous chromosome pairing at meiosis	GO Biological Process Annotations 2023	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.66
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37518
OBSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0099
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58074
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33414
Perturb_14873_KO_H11_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.05962
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
ion binding	GO Molecular Function Annotations 2015	1.0	null
homologous chromosome pairing at meiosis	GO Biological Process Annotations 2025	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9142
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30506
ABCB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12989
homologous chromosome segregation	GO Biological Process Annotations 2025	1.0	null
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05442
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00916
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	2.18987
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18473
Tetrad of microspores	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.952
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38437
GSE198228,GSE198245_0_v_2_apoe_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0714
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2912
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877318
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.331
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0858
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97547
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9294
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05294
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.224
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18872
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.95053
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.13203
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43835
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12027
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48914
Zinc finger, RING-type	InterPro Predicted Protein Domain Annotations	1.0	null
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	2.44621
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18473
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49293
Perturb_10418_KD_Nuak1_ERP105467	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.66676
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0968
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998986
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84713
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63573
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59646
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SHPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5222
NBEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.044
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08371
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2302
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66534
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878359
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5193
binding	GO Molecular Function Annotations 2015	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.222
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911055
MutSgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.442
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42171
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7533
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0106
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.676
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41124
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1049
Nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.483
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18909
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.5
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7388
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCIMY5	DepMap CRISPR Gene Dependency	1.0	2.10461
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15849
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.663
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41177
Perturb_2442_KD_DDX5/DDX17_SRP098687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.15105
SUMO transferase activity	GO Molecular Function Annotations 2023	1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04046
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06297
GSE148888_0_v_1_fstl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18618
Perturb_14879_KO_H14_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.51944
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.2076
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9225
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ubiquitin-like protein transferase activity	GO Molecular Function Annotations 2023	1.0	null
Perturb_16464_OE_Zfp36_SRP255505	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.73986
Lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08956
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3538
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.926856
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18473
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Kidney_GSE9493_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2606
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1517
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14992
CAOV4	DepMap CRISPR Gene Dependency	1.0	3.97918
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.553
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45211
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.52367
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44258
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54822
protein sumoylation	GO Biological Process Annotations 2023	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02777
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
PCI4B	DepMap CRISPR Gene Dependency	1.0	2.91278
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.884
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7184
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05066
Perturb_9108_KD_STAT3_SRP363695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.1795
Perturb_10270_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.65636
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6485
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.901413
Synaptonemal structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6113
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53553
Perturb_13390_OE_NSD2_SRP199225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.14435
Condensed chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.869975
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0078
ANKRD61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83333
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18618
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0943
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
Perturb_7780_KD_NUDT21_SRP017305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.96848
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11359
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5394
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9779
CDC37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55512
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01881
MPRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38063
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11951
OSC20	DepMap CRISPR Gene Dependency	1.0	2.58695
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-1.18262
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14518
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24863
HO1U1	DepMap CRISPR Gene Dependency	1.0	2.11493
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14992
protein ubiquitination	GO Biological Process Annotations 2025	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32971
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
MSTO211H	DepMap CRISPR Gene Dependency	1.0	2.1465
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998986
Perturb_5623_KD_SOX2_SRP307776	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.74949
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.9158
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9577
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997798
Fanconi anemia complementation group F	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.458
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6371
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4615
GSE155530_1_v_0_ace2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4376
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.601
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33984
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12211
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46951
DOK	DepMap CRISPR Gene Dependency	1.0	4.3363
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16248
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Condensed nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26195
HCC827	DepMap CRISPR Gene Dependency	1.0	2.34665
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73528
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04871
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56636
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.978474
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.22
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81865
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.13895
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40794
molecular_function	GO Molecular Function Annotations 2015	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09882
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908324
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13165
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970787
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47914
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23875
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18896
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36598
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1443
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983695
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26626
Germarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
496100342_PCx_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23867
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08323
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14992
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862811
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.808
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1563
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29826
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7951
stomach	GTEx Tissue Gene Expression Profiles	1.0	0.879816
Perturb_8479_KD_CSDE1_SRP117243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.47403
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.25
Perturb_15983_KO_Larp7_SRP189392	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.72643
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2149
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0824
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00747
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
Acute lymphoblastic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.852729
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31824
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983695
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12008
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.09786
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887645
Nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.980197
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15188
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.87207
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01149
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.936882
GSE136591_0_v_1_akap11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02241
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39218
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7685
LS180	DepMap CRISPR Gene Dependency	1.0	2.50879
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03468
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23706
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52383
Synaptonemal complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4512
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927722
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16646
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30098
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SELENOF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45529
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7487
EIF3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6001
XRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81356
GSE225218_0_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKUT1	DepMap CRISPR Gene Dependency	1.0	2.54489
Perturb_14687_KO_Pax6_ERP022747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.02874
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54159
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
UACC893	DepMap CRISPR Gene Dependency	1.0	4.62076
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06608
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1071
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.64
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84975
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15976
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875717
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15624
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	3.82869
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-FL_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9178
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8578
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955286
SOX13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51385
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977692
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.832092
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4485
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53351
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0764
NIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27742
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90636
GSE150688_2_v_0_ursolic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51002
GSE115363_3_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9512
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.484
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54531
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85218
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7987
GSE199204,GSE211619_4_v_7_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
protein modification by small protein conjugation	GO Biological Process Annotations 2025	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09882
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.07013
SNU478	DepMap CRISPR Gene Dependency	1.0	2.27157
GSE233679_6_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22394
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07401
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5295
CKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98422
FBXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11464
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7797
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7631
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927722
Endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.267
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79763
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6224
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90732
LSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25088
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17961
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2787
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.019
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4085
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14992
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984493
GSE196117_6_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22492
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17253
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09475
TMK1	DepMap CRISPR Gene Dependency	1.0	4.48185
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45373
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3014
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7945
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.52
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31901
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18473
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2683
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836338
NCIH1373	DepMap CRISPR Gene Dependency	1.0	3.18191
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.98172
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28149
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20816
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31442
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.907
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.28901
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5006
Perturb_9855_KD_MSI2_SRP096137	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.03699
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PSS008	DepMap CRISPR Gene Dependency	1.0	2.43596
YBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23273
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.103
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910902
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869379
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26144
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.53112
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.034
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7685
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90072
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.017
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861805
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7295
ZNF232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29725
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26195
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16781
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00856
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938735
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8377
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20787
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.103
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.058
LPS141	DepMap CRISPR Gene Dependency	1.0	4.04942
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984493
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28025
tonsil	HPA Tissue Protein Expression Profiles	1.0	0.90172
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0321
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00776
GSE148066,GSE157787_3_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.574
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66076
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.106
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.6582
Perturb_16497_KO_MESP2_SRP153048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.97627
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03871
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94634
POLR2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08992
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97084
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12149
IM95	DepMap CRISPR Gene Dependency	1.0	3.09455
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991985
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2801
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05491
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OSC19	DepMap CRISPR Gene Dependency	1.0	4.27297
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04008
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.527
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9898
GSE221386_2_v_0_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08005
MYBBP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29082
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1673
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49697
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3608
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6918
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19681
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44976
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20379
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.863285
SKNSH	DepMap CRISPR Gene Dependency	1.0	2.2766
Zinc finger, RING-type, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.103
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12254
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65368
cation binding	GO Molecular Function Annotations 2015	1.0	null
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53034
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8221
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61014
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8199
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8674
Perturb_5059_KD_Usp7_SRP235595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.49526
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6376
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07345
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3684
Perturb_12681_KD_MYCL_SRP109645	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.64045
SUDHL5	DepMap CRISPR Gene Dependency	1.0	2.23323
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79814
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09915
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10478
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.228
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04243
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0623
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.37584
PEO4	DepMap CRISPR Gene Dependency	1.0	2.00561
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3574
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.865
Perturb_7527_KO_EED_SRP239128	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8265
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
GSE181749_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AU565	DepMap CRISPR Gene Dependency	1.0	3.4014
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28205
Xeroderma pigmentosum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24863
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64595
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3154
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22647
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26195
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25004
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4546
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8714
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5466
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3196
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22598
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.76148
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44257
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25715
ubiquitin protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1012
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957211
Leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04641
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2664
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43835
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825745
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00939
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2455
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.621
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28188
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9163
GSE201239_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998986
GSE146865,GSE146866_1_v_0_saracatinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1926
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01003
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03387
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6803
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03468
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7845
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46241
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42023
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29214
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07981
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.18235
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11972
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5047
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1135
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.8794
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853159
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6882
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.003
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9374
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.31851
UMUC11	DepMap CRISPR Gene Dependency	1.0	2.74254
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05464
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07841
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4576
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28645
MutLgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.361
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33864
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.06937
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04008
USP48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55642
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40709
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08371
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1944
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61561
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67138
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33361
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8544
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1325
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1248
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3282
ELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01012
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4943
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1578
WDR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18842
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8352
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03468
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9602
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43869
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28044
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYD88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09916
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9062
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22446
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.18519
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7241
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74363
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90678
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79814
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869379
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61952
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.604
Perturb_9889_KD_FIP1L1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.01388
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26195
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3844
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10487
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.08746
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.877
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03526
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4341
Linear element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57374
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76572
Perturb_12997_KO_rs2431697_ERP121303	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.54067
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40013
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.677
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.955661
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45566
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ovariole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7504
Antler	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94725
ES4	DepMap CRISPR Gene Dependency	1.0	4.04418
kidney	HPA Tissue Gene Expression Profiles	1.0	1.96109
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25059
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06719
TE9	DepMap CRISPR Gene Dependency	1.0	2.17555
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50404
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9169
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
ubiquitin-like protein ligase activity	GO Molecular Function Annotations 2025	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861805
GSE148066,GSE157787_11_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7736
SUMO transferase activity	GO Molecular Function Annotations 2025	1.0	null
ubiquitin-protein transferase activity	GO Molecular Function Annotations 2025	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916904
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22782
Triglyceride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3639
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36089
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
homologous chromosome segregation	GO Biological Process Annotations 2023	1.0	null
Perturb_5092_KO_Max_SRP078684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.70648
Perturb_9920_KD_NELFE_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.8686
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2013
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843238
GSE226115,GSE226116_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34818
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74786
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2055
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
peptidyl-lysine modification	GO Biological Process Annotations 2023	1.0	null
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0577
MEX3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67507
SMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90931
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.89881
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982931
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869379
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44703
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02144
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9565
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07559
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7496
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.24732
H4C9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06256
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16664
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225218_9_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44283
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05826
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27846
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862822
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.682
HCC461	DepMap CRISPR Gene Dependency	1.0	2.07353
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54136
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55