association	dataset	threshold value	standardized value
BRD-K23923189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4419
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08778
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
TOP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4518
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.07312
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.729474
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35935439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45253
doxazosin-4988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65156
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30907
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886587
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936127
Actin cortical patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.026
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
Retinitis pigmentosa 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89775
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66343
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bergenin-5870	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.356
carbachol-5342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.30282
vision	GAD High Level Gene-Disease Associations	1.0	0.293278
PMC12347849-mmc1.pdf-34-ENSG00000152284_TCF7L1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15417
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
isoniazid-2246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32532
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28952
ALG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52304
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07852
Perturb_2615_Mut_SF3B1_SRP249914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.0395
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.095
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928082
families	GeneRIF Biological Term Annotations	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2015_KO_Slamf9_SRP199215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.2636
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
hsa-miR-4796-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K08142337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27677
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863747
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46072
SLC20A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15825
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.799
DCLRE1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63493
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.04685
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52111
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.752
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85116
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE211128_7_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16502
Rhoptry	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.743
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59373
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GARIN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07281
MITF	ChEA Transcription Factor Targets	1.0	null
Retinitis pigmentosa 59	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25647
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254792
horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69125
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03324
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ivermectin-7206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001917
RBPJ	ChEA Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974072
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08056
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OE33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48739
BRD-K18519876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58744
GOLGA6L9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26668
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846704
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
RXRA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
Scotoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.954
Attenuation Of Retinal Blood Vessels	DisGeNET Gene-Phenotype Associations	1.0	null
POR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65324
TENM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.724
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15809
rosette	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.220673
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cone-rod dystrophy 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39768
MTF2	ChEA Transcription Factor Targets	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K03512847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61621
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35983
TE5	CCLE Cell Line Gene CNV Profiles	1.0	2.39902
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	2.62679
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin-melanocyte	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.894589
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
Orofaciodigital syndrome IX	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043249
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Photoreceptor cell_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34474
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03168
estriol-7220	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37198
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30581
BRD-K11700411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20693
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17152
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal Recessive Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16191
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74728
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09495
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72494
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32436
cataract	HPO Gene-Disease Associations	1.0	null
trimipramine-3342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21446
retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.86232
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.178
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197562_2_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06251362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10801
TMEM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26421
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9759
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924555
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393819
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06105
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88414
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal cone dystrophy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173873_12_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	1.0	0.852436
Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE229914_1_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
C5orf34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39426
COL8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47628
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87795
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.506672
Perturb_16970_KD_AJUBA_SRP253076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.67504
CRCGN015_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82862
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.959581
amikacin-5314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
flutamide-3885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065212
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835823
COLO704	CCLE Cell Line Gene Expression Profiles	1.0	2.19906
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.13248
GSE249544,GSE249637_6_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDC14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63896
LN340	CCLE Cell Line Gene Expression Profiles	1.0	3.40798
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fendiline-3190	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98438
Perturb_13012_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_NFIA-Logfold_change_threshold_1_0_1_NFIA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7479515-mmc4.xlsx-ST-RELA-variable-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27236794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53394
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72402
sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129505
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36282
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.196
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.826794
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867243
Retinitis pigmentosa 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5854
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1046
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00172
Tetraspanin, EC2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K03599607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44203
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.65539
YY1	ChEA Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34757
trichlormethiazide-4783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin-cd8-positive, alpha-beta cytotoxic t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_ID_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
dipivefrine-6766	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ovary	HPA Tissue Gene Expression Profiles	1.0	1.19004
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59016
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.45567
GSE215086_0_v_1_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60342
TDRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1566
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42521
GSE204929_0_v_1_ywhag_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blastocysts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16673
SCC-4	GDSC Cell Line Gene Expression Profiles	1.0	1.59457
JEKO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997083
external genital hypoplasia	HPO Gene-Disease Associations	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873587
VMRCRCW	DepMap CRISPR Gene Dependency	1.0	2.99112
C17orf107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27304
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
proteasome accessory complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174911
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.048
NR2F2	ENCODE Transcription Factor Targets	1.0	null
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61438
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3215
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.994
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.27813
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13511_OE_Nfkbiz_SRP234708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881874
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VM-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049965
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03386
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53841
demeclocycline-3604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
SLC7A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15065
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911189
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33884
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71774
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90506
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.902995
abnormality of the penis	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zomepirac-3454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95327
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33474
BRD-K18245187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15783
ketanserin-4995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70273
BRD-K31393518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0728
zona incerta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.845969
SATB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5345
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07872
layer 3 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5374
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Bestrophinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
EBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75615
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inner SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04386
NFE2	ENCODE Transcription Factor Targets	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.76343
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.141
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1113
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07163
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11187
MMACHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42631
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66591
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57734337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2057
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63081
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0662
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
retinal vascular occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212608
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormal retinal photoreceptor layer morphology	MPO Gene-Phenotype Associations	1.0	null
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_7752_KD_YTHDF2_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.65582
Eye cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85385
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874281
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33615
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944499
glaucoma	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dihydroergocristine-7034	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73686
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.776454
BRD-K05802716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07561
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33997
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22989
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PNN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61289
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.863327
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.997743
BRD-K64404450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14356
INA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81016
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Chronic Low Back Pain	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846125
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.986777
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.044
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90982
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
BRD-K45398957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5049
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
chorioretinal abnormality	HPO Gene-Disease Associations	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03672
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.913141
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120958
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of connective tissue	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2724-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11101
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850707
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.734217
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
CRCGN008_HEPG2_24H:C11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15285
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6003
STAT3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12813
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
LRRC41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47236
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89792
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89049
Perturb_13016_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6522
BRD-K36804307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71478
DOK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40569
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31577
wortmannin-1243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
short-rib thoracic dysplasia 10 with or without polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YX-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tongue-endothelial cell of artery	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
Lung squamous cell carcinoma_LUSC_TCGA-68-7757-01B-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
methotrexate-6318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21285405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19792
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43989
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880972
Usher syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52877
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4974
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33662
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93933
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.3161
OE21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50303
TE6	DepMap CRISPR Gene Dependency	1.0	5.24834
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37965
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
irf1_17409403_nih3t3_gof_mouse_gpl81_gds2752	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.227512
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16174
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01014
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856475
Outer membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
BRD-K51760683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30083
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8224
cone-rod dystrophy 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
midbrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Salivary_Gland-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
Membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1826
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202303
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33365
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958229
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35561
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tongue-tongue muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839278
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85403
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53998
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03466
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00827
visual perception	GO Biological Process Annotations 2023	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80436
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.264
LAN2	DepMap CRISPR Gene Dependency	1.0	4.3426
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24681
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2567
BRD-K93357133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66758
GTEX-REY6-1126-SM-48FDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888734
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72544
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
C1orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93747
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89004
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.6306
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7845
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.641
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426109
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44648
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.35
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18185
Eye degenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02272
GTEX-QVUS-0426-SM-48FE3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833663
Lung adenocarcinoma_LUAD_TCGA-97-A4M6-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19575490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42068
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937728
Toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10373
PMC1847380__F15	PFOCR Pathway Figure Associations 2024	1.0	null
LIVF001-025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67791
becker muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.22937
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40101
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.888
photoreceptor outer segment	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12693
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88522
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4234
BRD-K07588901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35081
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung-mesothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0865011
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal ocular fundus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.898324
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872653
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.00102
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071101
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7561
BRD-K05841284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88652
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82024
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00617
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.95015
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85145
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.138848
Lung squamous cell carcinoma_LUSC_TCGA-58-A46K-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31371
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.105616
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07787
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32115
CRCGN014_HEPG2_24H:N12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42706
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.99697
ELF1	ENCODE Transcription Factor Targets	1.0	null
Cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.518
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bardet-Biedl syndrome 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
PMC6739476__F7	PFOCR Pathway Figure Associations 2024	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40448
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05278
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.8683
abnormal eye electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
retina rod cell degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hESC_Derived_CD56+_Mesoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.841567
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05593
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19913
Bae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
bucladesine-5886	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19775
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.976707
Shoulder Pain	DisGeNET Gene-Phenotype Associations	1.0	null
COX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07343
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09112411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05694
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044246
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182542
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04598
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.494918
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001996
Stargardt disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.468
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5334
oxprenolol-3568	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37102
5194442-6558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70148
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.87438
CRCGN016_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61444
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4693
pioglitazone-5925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238108
MYOG	ENCODE Transcription Factor Targets	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.769
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01692
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75851
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845682
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11531_KD_THOR_SRP121007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.101
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00049
fenbufen-3721	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86192
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of carbohydrate metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
mitral valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.138642
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
non-growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83403
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30449
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.758
SUZ12	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.95135
cellular process	GO Biological Process Annotations 2015	1.0	null
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05517
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01831
KMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96041
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02931
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94282
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K05220907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14213
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968661
Meiotic spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.214
MYC	ENCODE Transcription Factor Targets	1.0	null
Exudative vitreoretinopathy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28706
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0185
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91608
PANX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52951
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831793
Perturb_1212_KO_Zfp580/Sp1_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.7119
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75348
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.363
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974281
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.842677
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828958
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.740515
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1353
EXTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01755
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38856
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.164
Hypnozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36093
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7403583-41598_2020_69884_MOESM2_ESM.xlsx-Sheet1-Supplementary_Table_1_Differentially_Expressed_Genes_FDR_q_0_05_in_U2932_ROCK2_KD_vs_Scrambled_shRNA_Constrols_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4650-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09092
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09468
hsa-miR-124-3p	MiRTarBase microRNA Targets	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52492
YY1	ENCODE Transcription Factor Targets	1.0	null
abnormal eye physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K17232330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71081
ZSCAN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72328
BRD-K78748401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14183
BRD-K75730049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32584
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.08881
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23303
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71475
MRPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4381
hypoplasia of penis	HPO Gene-Disease Associations	1.0	null
BRD-K18573205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63328
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65759
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21519
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56062
PMC3675946__F6	PFOCR Pathway Figure Associations 2023	1.0	null
TAL1_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PGM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01231
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4827
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31256
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927141
BRD-K87131514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36275
AB-18-YN11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273362
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.41156
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86179
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73472
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32633
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
4star	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.70308
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.015
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05113
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058949
facioscapulohumeral muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.328834
BNC1_KD_GDS1978_70_mouse_oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418861
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clenbuterol-4671	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K10343715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20624
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045908
PR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8849
BRD-K15499806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57891
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.688
luteolin-5004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.3
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0614
MKS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.073
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.50533
strophanthidin-7182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1171
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE113221,GSE113968_6_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13374_KD_L54E2_SRP225936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.7959
doxorubicin_homo sapiens_gpl550_gse1647	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22651517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23928
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44431
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55887
abnormality of the endocrine system	HPO Gene-Disease Associations	1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.66196
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56627
PMC3241422__F10	PFOCR Pathway Figure Associations 2023	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.842
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33066
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58017
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05466
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75397
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63645840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01487
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02272
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36204977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27758
cell adhesion	GO Biological Process Annotations 2015	1.0	null
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07882
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70678
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94542
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
BRD-K24930745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2294
BRD-K28108927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21538
abnormal retinal rod cell outer segment morphology	MPO Gene-Phenotype Associations	1.0	null
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8464
SNU201	CCLE Cell Line Gene Expression Profiles	1.0	1.82847
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-29	GDSC Cell Line Gene Expression Profiles	1.0	1.52397
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53555
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990628
oxprenolol-5871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01956
retinal rod cell degeneration	MPO Gene-Phenotype Associations	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16858
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.951
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K23ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358174
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34694
Tongue-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
hmc1	HPA Cell Line Gene Expression Profiles	-1.0	-1.27801
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60812
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
paclitaxel-1542	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.973283
Retinitis pigmentosa 56	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.04988
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleotide-excision repair factor 3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
15790403-Table1	GeneSigDB Published Gene Signatures	1.0	null
RNF170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.41373
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1627
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73481
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10898
abnormal retinal pigmentation	HPO Gene-Disease Associations	1.0	null
Midgut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2271
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP5Z1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323144
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.725465
Thymus-mature nk t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71785
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14143
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinal Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831318
BRD-K05734090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35163
abnormal somatic sensory system morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K93567937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00271
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36642
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07081
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6657
MEF2A	ENCODE Transcription Factor Targets	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67255
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GINM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.453
BRD-K65392908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01567
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11418
BRD-K19118372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04398
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99017
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.962688
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15964
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59005
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.157596
H357	DepMap CRISPR Gene Dependency	1.0	2.16085
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23899
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32094
WM1799	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49815
Large_Intestine-intestinal enteroendocrine cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.21293
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74607
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30644
Degenerative Polyarthritis	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04475
nuclear chromosome part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054892
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01454
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retinal artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.559062
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945576
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8754
BPH1	DepMap CRISPR Gene Dependency	1.0	3.91458
GTF2IRD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03906
Neovascular inflammatory vitreoretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K03352392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47287
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229701
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.626
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73707
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22646
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39326
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60205
Thymus-mesothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0875897
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.65085
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59088
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08447
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837659
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92287
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40145790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30272
BRD-K77824583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06149
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19198
Cystoid macular edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
abnormality of the optic disc	HPO Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31925
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35524
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MC-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203158_12_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00167
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tanespimycin-998	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38231
Retinitis pigmentosa 71	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
abamectin-2519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K96505704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70844
Melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
bicuculline-2796	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08763
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44244
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72964
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92033
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982419
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879785
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LN319	CCLE Cell Line Gene Expression Profiles	1.0	1.38271
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
cell projection part	GO Cellular Component Annotations 2015	1.0	null
retinitis pigmentosa	HPO Gene-Disease Associations	1.0	null
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04181
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224398
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3044
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.52729
Eye-b cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73812
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TAL1_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Compound leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
RPUSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4682
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24636
RELB-30642670-CTB1-HUMAN-PLACENTA-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	2.03049
BRD-K97485863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29753
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye-retinal ganglion cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
DIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19186
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DTWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71355
l-5178-y cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.506672
PMC13137955-ijbsv22p4243s2.xlsx-Sheet1-hTFtarget_E2F3_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97133
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tolazoline-4844	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10942
Leber congenital amaurosis 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Marshall syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85473
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13763
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824176
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20974
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25285
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903079
BRD-A59995060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06705
Retinitis pigmentosa 85	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
BRD-K36807301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31839
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20596
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5566
BRD-K13289658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0371
BRD-K95740363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82246
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69444
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
amoxapine-1513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
Retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.672
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978588
Lung squamous cell carcinoma_LUSC_TCGA-60-2720-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
isoconazole-7211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18705
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24545
RELA_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bed nucleus of the external capsule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0291
Developmental delay and seizures with or without movement abnormalities	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
BRD-K43484052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41016
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47367
Retinitis pigmentosa 84	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12140_KD_PRPF8_SRP093921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rotator Cuff Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Medial cortical node	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17812
Perturb_72_KD_DNTM3B_SRP315598	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.64081
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7
Mononeme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.723
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02457
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21218
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Achromatopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.967
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67357
HNRNPUL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00588
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924733
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89677
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	1.44332
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.01814
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.939742
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
KMT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86755
BRD-K55044152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37843
BL70	DepMap CRISPR Gene Dependency	1.0	2.26246
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94729
Perturb_17320_KO_miR106b~25_ERP121195	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.98616
BRD-K58534227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48517
BRD-K00974016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02844
BRD-K66463856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12119
Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06109
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32542
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88596
GSE203072_2_v_3_rpl3l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monorden-4443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39932
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09732051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27628
ZNRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50761
primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27495
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.73338
aciclovir-4683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tetrahydroalstonine-2748	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
amiodarone-3296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4071
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.34855
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Large_Intestine-gut endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0897669
hsa-miR-2115	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862492
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221793
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22933
BNC1_KD_GDS1978_738_mouse_Oocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916419
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053661
Retinitis pigmentosa 46	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53493
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1339
mefloquine-2210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
U343	CCLE Cell Line Gene Expression Profiles	1.0	2.41619
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.751357
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77453
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.334
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11624
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3025
fluvastatin-3370	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2585
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17656
YPEL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53863
DSH1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2388
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80389
BEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00846
SNU1066	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63488
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37099
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64996
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53408
ZNF566	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39785
SP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977772
BRD-K12267335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11519
SEKI	DepMap CRISPR Gene Dependency	1.0	2.28543
NRL_Deficiency_GDS1693_237_mouse_Photoreceptors cells of retinas at P6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61321
KLF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10532
BRD-K51364219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52698
BRD-K00566460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8319
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9161
colecalciferol-3298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249977
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00321
trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187558
INSIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9587
BRD-K16255400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35457
NUSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80935
KG1C	CCLE Cell Line Gene Expression Profiles	1.0	1.37671
Bardet-Biedl syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Perturb_6707_KD_ELOA_SRP314942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.4896
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13J-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.615
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12959
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
BRD-K32723442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00532
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26945
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K61733751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47194
visual perception	GO Biological Process Annotations 2025	1.0	null
BRD-K78288885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07989
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.209918
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormality of vision	HPO Gene-Disease Associations	1.0	null
Lung-adventitial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
schistosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133148
BRD-K54732353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39793
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53086
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of light stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.78944
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08472
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18929
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
brain	HPA Tissue Gene Expression Profiles	1.0	1.75552
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
benzthiazide-4952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.44075
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.68405
Vitreous detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53915
abnormal retina morphology	MPO Gene-Phenotype Associations	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46377
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
lidocaine-1499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25865
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.913111
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory perception of light stimulus	GO Biological Process Annotations 2023	1.0	null
Retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24447
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88671
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.708
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.963
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117634
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
Patterned macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
CRCGN009_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01165
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24723
BRD-K08974502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32222
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91573
RELCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2816
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063988
ENOSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64729
OC-314	GDSC Cell Line Gene Expression Profiles	-1.0	-2.43249
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.080514
Photoreceptor Degeneration	DisGeNET Gene-Disease Associations	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.048
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0632
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967973
BRD-K49864183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26495
Red color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38927
STAT1	ENCODE Transcription Factor Targets	1.0	null
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198709
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34655
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clozapine-4670	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92532
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35671498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21727
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5594
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11101
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4541
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.464
RAD21	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914725
BRD-K51104732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07267
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08759542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07334
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0336
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Rhoptry neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.201
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91856
membrane part	GO Cellular Component Annotations 2015	1.0	null
Mucopolysaccharidosis type IVB	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
Lung-respiratory mucous cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
BRD-K74176533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07262
BRD-K39237487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23718
SNRPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13258
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03857
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of A5 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07384
BRD-K15269548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33968
CRCGN012_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79038
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.234
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.021
TAL1_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18892
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43495
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	181.373
g.8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06947
nitrofurantoin-3674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998996
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31629
S100A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30582
amiloride-4109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2403
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07429
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859577
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48039
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45745
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74183
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34548
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00193
BRD-K79370456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40921
BRD-K56536241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67872
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19595
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07076
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-CA-04-2009(H1N1)_18hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.33984
Muscle-tendon cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0897669
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.7922
CRELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15901
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11377
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8204
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Contracture	DisGeNET Gene-Disease Associations	1.0	null
retina degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
Ebl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
GSE213219_0_v_1_st3gal3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0395
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30305
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73327
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20477
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.60813
Acute Myeloid Leukemia_LAML_TCGA-AB-2830-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09001
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4027
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0346
Blood-cd4-positive, alpha-beta memory t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
Coronary Microvascular Disease	DisGeNET Gene-Disease Associations	1.0	null
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1668
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918846
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.56758
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11294
Choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.761
H1_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.844298
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35872
BRD-K37433647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52474
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06939
BRD-K05605336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93312
BRD-K09454191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03867
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01918
BRD-K21384875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04254
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59268
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3842
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.24874
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52331
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04418
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5524
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00728
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12203
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal Dominant Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.380368
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.632
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15238
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60463
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67721
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62716
short photoreceptor outer segment	MPO Gene-Phenotype Associations	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05671817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02322
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.029
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99783492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47002
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0145
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75784
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71391
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829416
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.0134
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25654
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34233
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76481
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7L-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K10416099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82673
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0825
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	2.14105
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87068
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10323
BRD-K07813434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24943
nonmotile primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.72369
brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73494
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3751
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063484
Metabolic Syndrome X	DisGeNET Gene-Disease Associations	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68442
serotonin-3311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K81160595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.024
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38099
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48991
GSE179031_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84577
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22017
SLFN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98406
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885249
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01454
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77059
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76489
MAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70969
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.711603
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19133
intestinal schistosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.348981
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22135
NCIH1437	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42778
Piriform area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18514
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02299
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058413
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957288
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07448
BRD-K05479183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85931
BRD-K22478004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12208
BRD-K03383196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37581
abnormal eye electrophysiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K76558091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14676
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59399
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02667
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26694226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65518
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928856
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1_KD_GDS2720_478_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cyclic adenosine monophosphate-5108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HUT78	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5005
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092231
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7009
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86359
intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16235
LPS510	DepMap CRISPR Gene Dependency	1.0	6.98298
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K08929846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50071
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16584_KO_Mir2182_ERP130060	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.35142
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acquired Hallux Valgus	DisGeNET Gene-Disease Associations	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119823
lymphoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064953
Choroidal sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.662
BRD-K85532500	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44608
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13044
Bardet-Biedl syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16554464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06032
CHD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic Obstructive Airway Disease	DisGeNET Gene-Disease Associations	1.0	null
flumequine-5529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66254
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD4	ENCODE Transcription Factor Targets	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	1.0	1.01147
Usher syndrome type 1D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.333
UBE2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80705
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Polarisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22967
Edema	CTD Gene-Disease Associations	1.0	1.06808
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58408512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38351
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.21251
CRCGN012_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01189
SKMEL2	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.859955
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30766
CBX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K06418332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56389
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.951628
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64626
Fetal Death	CTD Gene-Disease Associations	1.0	1.50801
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24293
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61607
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.791
Sarcoma_SARC_TCGA-DX-A48P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06431
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833185
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65005022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34388
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53311
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93913
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.956764
BRD-K75136523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13293
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246535
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64366
GSE183316,GSE183317_1_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151119_3_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965506
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87188
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAF1_02_81	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60613
Retinitis pigmentosa 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43279
BRD-K31778735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47088
Bradyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.511
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
retinal photoreceptor degeneration	MPO Gene-Phenotype Associations	1.0	null
FASTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2174
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09116
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898079
GSE164463_4_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3241422__F8	PFOCR Pathway Figure Associations 2024	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39795
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58696904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36185
Retinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.619
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19573
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881033
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54253
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056817
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995034
BRD-K21933068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05588
Joint Stiffness	DisGeNET Gene-Phenotype Associations	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.21
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57202
protoveratrine A-2800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.086
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40876
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22011492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60601
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04321
retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CRCGN014_HEPG2_24H:L05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80489
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36609
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9303
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3592
Perturb_15901_KD_Jun_SRP361315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3318
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1702
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Heart-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13604
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39764
CLDN19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29956
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
system development	GO Biological Process Annotations 2015	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881672
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_348_KO_KDM2B_SRP250460	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.76799
BRD-K02301426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78707
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.419623
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18537
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992888
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.21402
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3558
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K40220562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19674
Apical plasma membrane urothelial plaque	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.115
Endocytic patch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07084
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nicotine_myzus persicae_gpl9470_gse18658	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20888
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
suloctidil-6675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Autosomal dominant nonsyndromic deafness 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
661W cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
PFKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02034
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.52956
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73438
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19815
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5474
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8396
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41097
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941652
BRD-K15282144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35228
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06312
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.083
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20862
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3835
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8408
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.740965
adipose tissue	HPA Tissue Gene Expression Profiles	1.0	0.894891
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10944
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22817
cone-rod dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
Eye-retinal blood vessel endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20145
BRD-K02392990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45415
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laudanosine-2890	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K44807762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09523
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052674
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	12.499
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20424
moroxydine-1527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.694946
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72033
RERFLCAD2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48676
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ciliary membrane	GO Cellular Component Annotations 2015	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3044
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0197
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44324
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04762
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17069
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lordosis	DisGeNET Gene-Phenotype Associations	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69895
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891682
GATA2_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital Dysplasia Of The Hip	DisGeNET Gene-Disease Associations	1.0	null
Microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.331
Retinoschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
ChIP_MYCN_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
hyoscyamine-5099	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K71919612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37544
Hereditary choroidal atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.701
Contracture Of Elbow	DisGeNET Gene-Phenotype Associations	1.0	null
sulfamethoxazole-4690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08021
Perturb_16895_KI_Htt_SRP250656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.00564
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.715458
neuron differentiation	GO Biological Process Annotations 2015	1.0	null
17683608-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89892
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.115
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32341
glibenclamide-5849	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28056
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Rod photoreceptor disc lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.131
BRAF_druginhibition_175_GSE42872	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.43785
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5956
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25113
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064607
ENPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26821
retina	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15502
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.976764
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.771819
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNASEH2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11713
BRD-K04667232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.15745
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48144
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01057
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.095
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92339
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22318
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27304
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22838
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCCSUP	DepMap CRISPR Gene Dependency	1.0	2.37087
ZNF281	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42152
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Atypical Scarring Of Skin	DisGeNET Gene-Phenotype Associations	1.0	null
furazolidone-3358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39639
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40181
pindolol-6834	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24461
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78076
metaraminol-3669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K50287215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10808
X- Linked Recessive	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39084
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13421
TRIM28	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2455
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15508005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.6019
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18264
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85473
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinitis Punctata Albescens (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.913
BRD-K88974575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4267
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34177
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96901
pentoxyverine-4649	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09658
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50253
degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182375
GTEX-TSE9-0011-R7A-SM-3DB7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10457
Tetraspanin/Peripherin	InterPro Predicted Protein Domain Annotations	1.0	null
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22263
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27396
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.677
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885973
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05565
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069682
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE134615_1_v_0_lats1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12866
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14487
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929018
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0576
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
FUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71531
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50575
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114538
trichostatin A-6874	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05545
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262375
nomifensine-7217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NPJ8-0526-SM-3MJHN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08699
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28434
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56968
CRCGN009_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01132
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.89738
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21875
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15741_KO_Nr2e3_SRP086591	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.8932
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0145
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03352
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
Retinoblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.52424
BRD-K76942055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41399
UBTF	ENCODE Transcription Factor Targets	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4604
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
type iii intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.23922
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051831
macular	GeneRIF Biological Term Annotations	1.0	null
Perturb_9646_KO_LFNG_SRP153047	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.62863
meclozine-4646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5831804__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Partial central choroid dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.701
CRCGN013_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87233
Cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
ARHGDIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99349
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.058
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859552
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.702
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850181
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52911
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07244
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN443	CCLE Cell Line Gene Expression Profiles	1.0	1.59085
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52813
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92033
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61401
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25753
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32289
RNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37225
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2696
Trichocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61628
Protein storage vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47914
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Congenital Spondylolisthesis	DisGeNET Gene-Disease Associations	1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26109
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99977
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fat_8a	HPA Tissue Sample Gene Expression Profiles	1.0	0.933658
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A44S-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K74486924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69454
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9726
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44813
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.80427
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	0.835689
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16743
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
p3u1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
ARMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18335
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30696
Liver-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.284
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906944
eye photoreceptor cell differentiation	GO Biological Process Annotations 2015	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872919
CTIP_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
debrisoquine-3207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K83229680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31879
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_14495_KO_Tcfl5_SRP322934	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.15787
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00893
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DGKZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98087
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3411
hsa-miR-361-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.25647
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80735
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.908482
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65923
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29209
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03867
tretinoin-6971	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Retinitis pigmentosa	ClinVar Gene-Phenotype Associations 2025	1.0	null
Hereditary Macular Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:I16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12845
Hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14197
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97472
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.27237
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09279
BRD-K15992638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31159
SLC35A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4217
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31305
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08271
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.047
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus-5975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1061
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.10434
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Middle ear cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
Perturb_13014_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.4089
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33843
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991912
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92033
Lung squamous cell carcinoma_LUSC_TCGA-58-8391-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97784715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12034
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09472
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney-cd4-positive helper t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31718
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retinal macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.09053
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57542
NCI H322M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01935
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.827254
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55118
dorsalrootganglion	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.869149
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal posterior eye segment morphology	MPO Gene-Phenotype Associations	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01454
HEC59	DepMap CRISPR Gene Dependency	1.0	8.21117
alter	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02927
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04336
BRD-K51275565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14539
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51N-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_7106_OE_Erbb2_SRP245626	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.199
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the retinal vasculature	HPO Gene-Disease Associations	1.0	null
PIGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23041
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48563
Eye-ciliary body	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.85976
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.57567
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2339
BC3C	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66341
GOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05009
Medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
Congenital muscular dystrophy-dystroglycanopathy type A5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
Microneme membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.188
TAF7L-23326641-C3H10T1-2-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43295
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.856658
BRD-K07798964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02917
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55992
gallamine triethiodide-2221	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	3.95247
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	2.08084
GSE123638,GSE123639_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058044
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.05255
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68468
X-linked juvenile retinoschisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
vermiform appendix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
BMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90655
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910372
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.01056
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87791
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hyperinsulinemia	HPO Gene-Disease Associations	1.0	null
ANAPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15227
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183316,GSE183317_3_v_5_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3076323-pone.0018064.s016.xls-MYCN_targets_Marson_GSE6007-Unnamed_1_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
LRRC10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37977
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24234
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964689
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78608
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39571
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
u87	HPA Cell Line Gene Expression Profiles	1.0	0.92539
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
EW-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56894
CRCGN011_HEPG2_24H:C17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10985
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15001
PMC6664756-12915_2019_679_MOESM2_ESM.xls-Table_S7_DRGs_in_ELF1-DOX-Gene_Name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4786
haloperidol-1539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.24619
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3039
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29717
CRCGN010_HEPG2_24H:B05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07469
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C2orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9282
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16782
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76422
BRD-K35208671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49755
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
TMEM131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17539
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09279
Perturb_9853_KD_LUC7L2_ERP124746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83379
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24114
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69266
Obesity	DisGeNET Gene-Disease Associations	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84492
BRD-K98757606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48743
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20256
disorganized photoreceptor outer segment	MGI Mouse Phenotype Associations 2023	1.0	null
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN428	CCLE Cell Line Gene Expression Profiles	1.0	1.95877
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.451
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory perception of light stimulus	GO Biological Process Annotations 2025	1.0	null
Perturb_15776_OE_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.97306
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11548
BRD-K50423606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36353
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.43519
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05393
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31284
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.50184
retinitis pigmentosa	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NCI-H378	GDSC Cell Line Gene Expression Profiles	1.0	1.52827
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87557
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23691
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	3.16304
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65215
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.217
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
COLO205	DepMap CRISPR Gene Dependency	1.0	3.52957
BRD-K16673836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51554
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05319
mo-b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01856
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98589
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.912372
Cone dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.468
Mental Disorders	CTD Gene-Disease Associations	1.0	1.13552
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02011
Perturb_16770_KO_Lrch1_SRP261798	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.41446
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.678
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46488
BRD-K70428675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28608
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
ozagrel-3503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2198
sulfafurazole-4661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STARD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59099
BRD-K26187220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13302
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00658
Muscle-mesothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
Telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73547
Nasal Bridge Wide	DisGeNET Gene-Phenotype Associations	1.0	null
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
BRD-K54538111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16301
SMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28917
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11157
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22081
doxazosin-6642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33316
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836682
midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224398
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35691
NCIH522	DepMap CRISPR Gene Dependency	1.0	2.65415
BRD-K10148216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08643
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20076
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gyrate atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.339
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ciliary membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.008736
CRCGN014_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42424
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12915
TTC642	DepMap CRISPR Gene Dependency	1.0	8.19281
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69141
GSE166914_1_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221577_4_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26126
cotinine-4650	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
PMC7571286-tvst-9-11-16_s004.xlsx-MaxQuant_-_SRF-Unnamed_209_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
Neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.112
BRD-K81515704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43693
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K76738405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3205
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05138
valproic acid-5569	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14457
nisoxetine-3117	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06264
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22379
abnormal retina morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.22566
Uterus-immune cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
Macular Edema, Cystoid	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.50964
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73945
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15148
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05457
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058861
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19608
hyoscyamine-5524	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64923
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060795
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.89736
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1176
BRD-K52441396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09267
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41912
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985083
BRD-K07348252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23491
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45287
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.425
BRD-K99939085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25178
Enhanced S-cone syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.169
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
plasma membrane region	GO Cellular Component Annotations 2015	1.0	null
abnormality of the nasal bridge	HPO Gene-Disease Associations	1.0	null
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35208
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00051
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084007
PRECLH	CCLE Cell Line Gene Expression Profiles	1.0	1.43677
Rod-Cone Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0239
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71037
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45025
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218165
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34813
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964931
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.562
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8444
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8315
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998333
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
plague	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.275801
they	GeneRIF Biological Term Annotations	1.0	null
wide nasal bridge	HPO Gene-Disease Associations	1.0	null
BRD-K08416880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09355
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24603
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70048
BRD-K56253099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53655
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29259
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67255
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K48113764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32084
Cdr2 medial cortical node complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13587
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13596
RUNX3	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877806
AJM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83821
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of corneal thickness	HPO Gene-Disease Associations	1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64536
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53493
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1427
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.49026
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-1426-SM-3LK5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02408
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.55837
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03138
Leaflet of membrane bilayer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.244
hearing impairment	HPO Gene-Disease Associations	1.0	null
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96502
neurological system process	GO Biological Process Annotations 2015	1.0	null
GSE224311_3_v_1_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV318	CCLE Cell Line Gene CNV Profiles	1.0	2.73742
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05286
loxapine-1516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22087
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K02053819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59095
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24713
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
red-green color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.196459
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884743
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09467
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50441
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995684
TAL1	ChEA Transcription Factor Targets	1.0	null
BRD-K10176883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08313
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59809
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81758
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.11843
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27946
Hypertrophy	CTD Gene-Disease Associations	1.0	1.55995
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.887
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.953078
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-ddORF6_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59118
hsa-miR-4267	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.918152
pelvic inflammatory disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.302698
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050646
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24518
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10447
single-organism process	GO Biological Process Annotations 2015	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064237
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30652
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.9235
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36171
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.73839
EYA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72288
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
meropenem-3564	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882981
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88792
indapamide-2322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82102
MOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30584
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970284
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10942
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K62358627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14542
exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.72322
VMCUB1	CCLE Cell Line Gene CNV Profiles	1.0	2.73677
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.53833
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059503
SBF transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08623
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01687
abnormality of the retina	HPO Gene-Disease Associations	1.0	null
Leber congenital amaurosis 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
GA-87-BR97_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241608
etanidazole-2510	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal retina blood vessel morphology	MGI Mouse Phenotype Associations 2023	1.0	null
additional	GeneRIF Biological Term Annotations	1.0	null
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Retinitis pigmentosa 72	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
quinpirole-3539	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cone matrix sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.521
baclofen-1536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061861
Lymph_Node-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
CRCGN015_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62475
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32322
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99742
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61734
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.92694
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487106
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06925
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48435
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65797
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
BRD-K15373812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.00788
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.33133
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893248
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
optic atrophy	HPO Gene-Disease Associations	1.0	null
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97539
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2259
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
pigmentary retinal degeneration	HPO Gene-Disease Associations	1.0	null
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98627
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01019
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930222
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-2.7105
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63141
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sleeplessness	DisGeNET Gene-Phenotype Associations	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38128
sulfabenzamide-4979	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959257
Early Awakening	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43569
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18723
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF708	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64904
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.606916
Perturb_6985_OE_Ppp3cc_SRP321708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3133
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60895802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93488
novobiocin-2990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51573
Substantia nigra	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Endopiriform nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25991
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1151
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K82578220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61283
ASXL1	ChEA Transcription Factor Targets	1.0	null
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61972
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TK10	BioGPS Cell Line Gene Expression Profiles	1.0	1.13766
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08716
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828692
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5125
Peripheral retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0145
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3	ENCODE Transcription Factor Targets	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.632
tiabendazole-4579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09117810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50907
Ciliary necklace	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.186
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60024
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062039
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04755
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81752
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63519
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81703
CALU6	DepMap CRISPR Gene Dependency	1.0	2.25286
ELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
Peripherin/rom-1	InterPro Predicted Protein Domain Annotations	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880678
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2052	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62243
BRD-K33272704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02516
Abnormality Of Fundus Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12849
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07545
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97309
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K14139166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58267
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6576
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCV JFH-1_48Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.39999
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.54362
visual impairment	HPO Gene-Disease Associations	1.0	null
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69131
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K74656131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87382
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0765
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS37D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95311
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2249
MRPL53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39334
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87957
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20312
TAL1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71942
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042698
Photoreceptor outer segment membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
functional abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854235
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06214
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20397
membrane	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33954
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.42682
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840143
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
Muscle Spasticity	DisGeNET Gene-Phenotype Associations	1.0	null
primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.48814
BRD-K63987422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07823
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61544
18277965-Table4b	GeneSigDB Published Gene Signatures	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.39896
Spleen-regulatory t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044942
KIF26A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1466
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.68828
cone-rod dystrophy 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22508
PRPH2	Pathway Commons Protein-Protein Interactions	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.268332
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17964
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.911
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K63616423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20819
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19644
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29843
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892015
IRF1	ENCODE Transcription Factor Targets	1.0	null
GSE173873_12_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27535
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43X-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73373
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19984
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824208
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66361
nafcillin-3323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1109
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.250695
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12571111-qiaf131_supplementary_data.xlsx-ST2-Supplementary_Table_2_Results_of_the_two-sample_MR_analysis_on_the_causal_role_of_CD4_T_cell_expression_profiles_on_CRC_development_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896461
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Centriolar subdistal appendage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.434523
Lung-bronchial smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8935
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1575
TEAD4	ENCODE Transcription Factor Targets	1.0	null
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4556_KD_Ncor2_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.77961
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RDES	CCLE Cell Line Gene CNV Profiles	1.0	1.47346
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12137
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00633
BRD-K09607752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84753
BRD-K81322049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04551
FAM120A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0513
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.874875
BRD-K56654013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03962
anabasine-6074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_572_KO_Plod1_SRP321648	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.71537
TINAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46008
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t-lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132414
Oguchi disease-2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
PEDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65268
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
CRCGN013_HEPG2_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71311
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12123
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13425292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.78279
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
LN235	DepMap CRISPR Gene Dependency	1.0	2.73895
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27152
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
eye disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5137
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92925
BRD-K04470135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.84096
HEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39283
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5485-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
acebutolol-4976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11085
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.323
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rom1	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04593
plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00547
ELK1	ENCODE Transcription Factor Targets	1.0	null
Spondylolisthesis	DisGeNET Gene-Disease Associations	1.0	null
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
PHETA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96446
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LN235	CCLE Cell Line Gene Expression Profiles	1.0	1.81875
PHF8	ENCODE Transcription Factor Targets	1.0	null
PMC7002344__F10	PFOCR Pathway Figure Associations 2024	1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
cos-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24744
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24559
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.49848
GSE206516,GSE206518_2_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3767
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81369
BRD-K15928912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41339
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
fluspirilene-3086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NRL_Deficiency_GDS2936_629_mouse_Retinas - 2 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20535
FOS	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825693
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02745
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.2662
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
CRCGN013_HEPG2_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10961
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56575
Congenital Hallux Valgus	DisGeNET Gene-Disease Associations	1.0	null
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64735
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63409
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.62605
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45107
brinzolamide-6670	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TWIST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31556
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.882512
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72413
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74018
USP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23107
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2735
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4765
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95972
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.196175
kanamycin-3224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57597
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.37885
BRD-K91202220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10705
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00867
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC3241422__F10	PFOCR Pathway Figure Associations 2024	1.0	null
AIRE_KO_GDS2015_33_mouse_thymic epithelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58926
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23152
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.898
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27488
Prestwick-664-3715	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1743
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.076
EFEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81305
Aural Atresia, Congenital	DisGeNET Gene-Disease Associations	1.0	null
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48182
GTEX-U8XE-1026-SM-4E3HM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866512
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1019
abca4	GeneRIF Biological Term Annotations	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917813
decreased corneal thickness	HPO Gene-Disease Associations	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gabapentin-3472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66503
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77746
abnormal retinal blood vessel morphology	MPO Gene-Phenotype Associations	1.0	null
ovary_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.08166
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.21862
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834611
caused	GeneRIF Biological Term Annotations	1.0	null
hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.960312
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.537
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00335
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230911
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
liothyronine-3324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73567
Retinitis pigmentosa 66	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18998
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1981
biotin-6689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MUTZ5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35113
hsa-miR-499a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other	GAD High Level Gene-Disease Associations	1.0	0.293278
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197562_0_v_3_nox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4394
meticrane-1671	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Retinitis pigmentosa 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
North Carolina macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50024
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
pioglitazone-5972	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40254
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14347
CCKBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48358
PCGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90308
PMC5486049__F5	PFOCR Pathway Figure Associations 2024	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48514
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23805
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.729
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42441
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3546
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.53056
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23123
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37356
SUDHL8	DepMap CRISPR Gene Dependency	1.0	2.97635
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10245
HT-1376	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:D06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09455
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40334
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13481
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.88764
Perturb_5632_KD_JQ1_SRP142503	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34764
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11377
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87093
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
GSE93309_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cefamandole-3436	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05449
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47261
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12003101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58926
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	190.776
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56667
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062133
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.59655
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70087673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35581
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11296
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14866
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55665
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77795_2_v_1_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bendroflumethiazide-3840	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21609
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
Acute Myeloid Leukemia_LAML_TCGA-AB-2820-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75E-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063528
Perturb_7180_KO_TrEx_SRP163035	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.14892
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.63485
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.667655
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35291
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.476201
BRD-K44371786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35741
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55816
rhein	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03828
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49974
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19567
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940737
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07411
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16081
GSE173282_1_v_0_marchf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912027
Vital Capacity	DisGeNET Gene-Phenotype Associations	1.0	null
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61631
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92033
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1013
boldine-4122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42842
16284748-TableS4	GeneSigDB Published Gene Signatures	1.0	null
16885382-Table2	GeneSigDB Published Gene Signatures	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C1-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907627
CRCGN008_HEPG2_24H:L15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84945
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37589
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Aland Island eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.835065
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1478
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Joubert syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54572
BRD-K65245206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64185
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276495
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47305
Perturb_6502_KO_SOCS3_SRP168556	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.43718
TAF7L	ChEA Transcription Factor Targets	1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45657
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49688
RNASET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35287
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-7173-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dacarbazine-4480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cone-rod dystrophy 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825187
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.873135
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dropropizine-5531	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20437
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33565
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03188
etidronic acid-4564	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0442
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3419
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75301
Fundus albipunctatus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.29
SMAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.62336
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.45849
sensory peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180652
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Blood-cd8-positive, alpha-beta cytokine secreting effector t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130715_1_v_0_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
NCIH2122	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96822
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909498
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.55182
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40008
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08109
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.361977
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484376
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51568355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80456
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01485
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48183
Orofaciodigital syndrome X	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K27228812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33182
cone-rod dystrophy 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
GTEX-RVPV-0011-R5A-SM-2TF69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13458
gentamicin-7237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62891
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Eye-eye photoreceptor cell	Tabula Sapiens Gene-Cell Associations	1.0	17.956
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98497
Retinitis pigmentosa 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.389
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24606
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
ZEB1	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.877806
culture fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278603
glipizide-4991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.31476
LPS6	DepMap CRISPR Gene Dependency	1.0	5.99999
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43083
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85252
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0327
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2803	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853817
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.080218
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.66038
SKMEL28	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.995037
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15792
CRCGN012_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72463
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fungal-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95176
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02337
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58844095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16157
Retinitis pigmentosa 69	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
5253409-961	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sulfanilamide-6810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.911623
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42551
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52517
BRD-K18599462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93116
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29895
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03376048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57503
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842797
isocorydine-6843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22328
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
AKT1_knockdown_43_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.74218
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38826
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07084
CRCGN015_HEPG2_48H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81503
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE441T	CCLE Cell Line Gene CNV Profiles	1.0	1.66594
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15776
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
MELHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54372
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93553
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-74-PJ26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214015
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.936831
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11286
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069245
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04578
COS-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
Retinitis pigmentosa 89	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.5024
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4504
Leber congenital amaurosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870733
cinchonine-4107	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09468
LTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19775
H3K18ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07579
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
pheneticillin-6105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PLZ5-0426-SM-3P612	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962623
MAFF	ENCODE Transcription Factor Targets	1.0	null
abnormal blood vessel morphology	MPO Gene-Phenotype Associations	1.0	null
thin retinal outer nuclear layer	MPO Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
Loss Of Cervical Lordosis	DisGeNET Gene-Disease Associations	1.0	null
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.984919
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7804
GART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49183
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23628938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20584
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09785
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.02336
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16743
Craniometaphyseal Dysplasia, Autosomal Dominant	DisGeNET Gene-Disease Associations	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32047
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.4447
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9474
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.74348
Sarcoma_SARC_TCGA-FX-A3NJ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52862
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254447
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.856312
Congenital Hypoplasia Of Penis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K44722555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28603
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.17
Perturb_9934_KD_AKAP8L_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.21876
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
Perturb_2743_OE_NTN4_SRP361955	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Iris dilator muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92376
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0752
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40883
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921897
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852241
Perturb_12884_KO_Ccnk_SRP127682	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.74418
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.744122
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
THUMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46398
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
BEN	CCLE Cell Line Gene Expression Profiles	1.0	1.47248
BRD-K05350978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.00624
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69802
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55187
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15219
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.43184
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57363
Abnormality Of Retinal Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1586
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44115
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28247
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983068
inner CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906066
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.06442
macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.897461
BRD-K04092807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54615
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41486
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.74195
SFXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54421
chloropyramine-4414	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.997335
GTF3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42295
sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20804
VILL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3517
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65267
DNAJB1	Hub Proteins Protein-Protein Interactions	1.0	null
Bardet-Biedl syndrome 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
BRD-K49849398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35186
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal retina rod cell outer segment morphology	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	232.713
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3452
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66149
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8794
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.989731
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922963
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.938
PHF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27086
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14112
abnormal retinal neuronal layer morphology	MPO Gene-Phenotype Associations	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928218
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.0065
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.913461
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09722
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03484
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.976695
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92208
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
EPN1	Pathway Commons Protein-Protein Interactions	1.0	null
Decompression Sickness	DisGeNET Gene-Disease Associations	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gamma-tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.135
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21315
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46513
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1724
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4532
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16494
should	GeneRIF Biological Term Annotations	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202284,GSE202289_1_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hereditary spastic paraplegia 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.46
BRD-K11643336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25769
Perturb_11694_KD_XPO7_SRP270635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.86913
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950822
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53208
BRD-K19325444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.09784
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50943
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07236
levopropoxyphene-3543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02920459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19927
CEBPD	ENCODE Transcription Factor Targets	1.0	null
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15712
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995128
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834611
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06387
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	3.00949
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SLITRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73152
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105545
chr11_62598982_G_A_b38	GTEx eQTL 2025	1.0	1.41906
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09467
MTA3	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32921
GSE173873_1_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K18944654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19361
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7072_OE_hMYL2_SRP182648	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93086
C4I	DepMap CRISPR Gene Dependency	1.0	3.1591
KYSE-140	GDSC Cell Line Gene Expression Profiles	-1.0	-1.81714
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82131
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.368
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1878
Prestwick-674-3614	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
obesity	HPO Gene-Disease Associations	1.0	null
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATXN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25783
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00049
abnormality of the nasal alae	HPO Gene-Disease Associations	1.0	null
butyl hydroxybenzoate-4647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.90224
Peripherin/rom-1, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
increased body weight	HPO Gene-Disease Associations	1.0	null
BRD-K17609687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47117
prilocaine-2314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39159284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91011
CRCGN017_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58303
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5468
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
Hereditary retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19319
metamizole sodium-3929	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66146
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36304
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17482
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02603
GSE130396_8_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-876-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21217
brain	GTEx Tissue Gene Expression Profiles	1.0	1.88742
MIEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59307
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915236
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21415
BRD-K88448214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85434
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3622_KO_SMARCC2_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.52686
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39786
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11832
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86821
FOXP2	ENCODE Transcription Factor Targets	1.0	null
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
hydralazine-3724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K52473839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47281
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81457
CP in rostral hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4306
PMC3675946__F6	PFOCR Pathway Figure Associations 2024	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.45739
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.150598
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1742
ZFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18849
BRD-K74114857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18929
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12341
Eye-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.658553
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16743
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37716
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.315
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28941
dystrophy	GeneRIF Biological Term Annotations	1.0	null
hydrocortisone_homo sapiens_gpl201_gse21909	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Exoerythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73562260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25239
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.931498
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74538
Eye-muller cell	Tabula Sapiens Gene-Cell Associations	1.0	2.22786
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.07713
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
BRD-K10276373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43903
GSE180951_1_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Progressive Night Blindness	DisGeNET Gene-Phenotype Associations	1.0	null
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86333
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834329
Retinitis pigmentosa 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Pancreas-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0255
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22651
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02148
BRD-K38170103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22614
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5978
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26288
Face	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.96312
Neck Pain	DisGeNET Gene-Phenotype Associations	1.0	null
Stress, Psychological	DisGeNET Gene-Disease Associations	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30472
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09413
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867881
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6544
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6448
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02965
LN215	CCLE Cell Line Gene Expression Profiles	1.0	1.43386
hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191841
SMC3	ENCODE Transcription Factor Targets	1.0	null
PMC1847380__F15	PFOCR Pathway Figure Associations 2023	1.0	null
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08189
BRD-K15188108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00178
CRCGN012_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10362
BRD-K35462787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09365
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70216
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PancreaticIslet	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9319
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2314
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17095
Autosomal recessive nonsyndromic deafness 18B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.766
FOSL2	ENCODE Transcription Factor Targets	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0826
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0604
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23859
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.15
rimexolone-5092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7971
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31465
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9446
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35937
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal somatic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K28598371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06623
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36187
GINS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22724
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
lumbar spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251279
CLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1645
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05491
Retinitis pigmentosa 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17099
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881578
night blindness	HPO Gene-Disease Associations	1.0	null
PMC5486049__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99625
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867713
ADSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78001
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7109
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02354
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34105
nefopam-4752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23394
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01454
BRAF_druginhibition_38_GDS5085	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.43785
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92057
GATA2	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976313
Lymph_Node-endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0897669
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57361
TNIK_knockdown_297_GSE17623	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.65949
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	0.980854
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.56371
Drug Resistant Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adult-Onset Night Blindness	DisGeNET Gene-Disease Associations	1.0	null
Perturb_13020_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
scarring	HPO Gene-Disease Associations	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mexiletine-2324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935533
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21277
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054753
Perturb_9957_KD_SNRNP200_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.13293
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormality of the choroid	HPO Gene-Disease Associations	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69839
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66564
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.77809
GSE114992,GSE114993_9_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01857
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
Perturb_15775_OE_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.7902
PMC5831804__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893363
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464174
BRD-K18173053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.20049
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79762
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866069
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79339
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2806
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01927
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57806
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59963
photoreceptor outer segment membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
C19orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05957
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84742
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
naloxone-4645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.06008
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.121
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.0681
Perturb_7751_KD_RPP20_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.34915
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33522
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60294
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435289
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.45
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.50635
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973201
KHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22058
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1129
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91521
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38978
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02549
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7521
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.09471
retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
diltiazem-5309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846085
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EGLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70663
efo21	HPA Cell Line Gene Expression Profiles	1.0	1.2253
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.53
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cefalexin-4654	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K66909712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61791
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.106
BRD-K42877297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01247
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44548010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15285
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10219
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Respiratory Distress Syndrome, Newborn	DisGeNET Gene-Disease Associations	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.7364
membrane region	GO Cellular Component Annotations 2015	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6485
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.953015
hydroxyachillin-2812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K60865324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1061
Lung adenocarcinoma_LUAD_TCGA-44-A47A-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLYWCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98809
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.64398
Color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.047
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13663
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06898
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44334
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91026
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46374
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40278
BRD-K30326216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56016
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833029
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal sensory neuron morphology	MPO Gene-Phenotype Associations	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23011
r8 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13291
BT16	DepMap CRISPR Gene Dependency	1.0	5.80818
uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.136296
Huelle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16959
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
juvenile spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.719654
sertaconazole-3550	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81795
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08441
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57771
abnormality of the vasculature	HPO Gene-Disease Associations	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.06231
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08207
SLC17A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45532
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08629159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02826
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948923
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
levothyroxine sodium-3249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830487
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838801
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.663
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26914
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38846
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04508
Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27488
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE166914_1_v_0_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88215
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86427
DEF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17436
bupropion-3180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72314
thiamazole-3898	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09092
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP1R3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76875
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rod photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.761
FC-20-EQ58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.374321
Anteverted Nostril	DisGeNET Gene-Phenotype Associations	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6356
Perturb_9973_KD_CSTF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76225
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00026
KAT2A	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01101
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.05573
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.269648
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14974
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11089
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66179
GSE173873_2_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COL9A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57669
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pregnancy Associated Hypertension	DisGeNET Gene-Phenotype Associations	1.0	null
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
pioglitazone-7523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB33_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971127
BRD-K02691653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11716
adenosine phosphate-3237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44913
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26007
NCI-H322M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal retinal photoreceptor morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K63858518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.719
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.911514
hycanthone-3229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.11722
KAT2B	ENCODE Transcription Factor Targets	1.0	null
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.996279
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	0.91623
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75226
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small_Intestine-gut endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
BRD-K47572485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09213
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060459
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31473
STAMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16019
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075348
nystatin-2500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45063
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32803
HL60	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05553
BRD-K64434200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0397
cognitive impairment	HPO Gene-Disease Associations	1.0	null
BRD-K40985311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07858
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45266
Macular retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.7677
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40501
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19212
egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236332
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062253
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.844
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.448346
Electroretinogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K94540403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6222
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26265
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6167
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11936_KD_SMARCD1_ERP132117	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.36794
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04906
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6773
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Serum bilirubin levels in metabolic syndrome	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Trachea-serous cell of epithelium of trachea	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51342
Retinal cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
Retinitis pigmentosa 88	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.828871
calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413532
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31216
BRD-K82202634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14926
Pyogenic Arthritis Of Hip	DisGeNET Gene-Disease Associations	1.0	null
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53727
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15529
HS936T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44829
NCIH2081	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6455
khellin-4987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93882
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88783
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12539
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal retinal outer nuclear layer thickness	MPO Gene-Phenotype Associations	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11671824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.125
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.51251
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19133474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99035
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
monorden-6938	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
gelsemine-4097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mitral valve prolapse	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.385193
Leber congenital amaurosis_Retina_GSE3249	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.54799
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98168
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06726
Retinitis pigmentosa 47	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03356
Interphotoreceptor matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.56
knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221291
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894148
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074772
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24782
Kidney Chromophobe_KICH_TCGA-KN-8422-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78477
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10255
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980141
BRD-K73859343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26221
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77085
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26228
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Chronic interstitial cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17957
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.889
ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.232386
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.108
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.9805
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76941
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03497
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12294
BRD-K87670244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12828
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.04314
PBX3	ENCODE Transcription Factor Targets	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01488
BRD-K16331797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14768
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90357
visual perception	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30891
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055674
glipizide-1508	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15335
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
talampicillin-3515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYCN-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
phthalylsulfathiazole-4653	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K72519622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33646
BRD-K31783246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43377
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43495
FN3KRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43573
isoetharine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74483
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38635
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
ABHD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44875
BRD-K56801250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06907
CFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35467
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02989
COMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14193598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58122
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K70819166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9642
RERFLCAI	DepMap CRISPR Gene Dependency	1.0	2.31373
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06277
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34767
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	1.5812
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89744
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986847
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93121
FOXP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90057
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50787
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5185
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.642406
CRCGN017_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68275
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98254
Perturb_7064_KO_Eed_SRP092655	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.81931
BRD-K02921955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.48208
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.691
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26034
Bone_Marrow-macrophage	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
BRD-K81810589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3759
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X5EB-0526-SM-46MVP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865053
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066073
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02097
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
riboflavin-2760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal glucose homeostasis	HPO Gene-Disease Associations	1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64684
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.209763
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5425
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912228
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873369
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861712
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849896
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64697
Perturb_10026_KD_TRIM56_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.09645
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.639
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
5279552-843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EP-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.145
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0426-SM-3MJHD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880799
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51492
RGS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97119
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09468
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859409
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29872
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00962
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90812
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860629
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942885
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
E2F4	ENCODE Transcription Factor Targets	1.0	null
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47179
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Phloem parenchyma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
chromosomal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047137
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0478
PMC7002344__F10	PFOCR Pathway Figure Associations 2023	1.0	null
neuron part	GO Cellular Component Annotations 2015	1.0	null
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Perturb_9982_KD_SF3B4_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.0876
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.52908
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.962635
GYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51791
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26951
abnormal ocular fundus morphology	MPO Gene-Phenotype Associations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M040416	DepMap CRISPR Gene Dependency	1.0	10.6513
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.40605
abnormality of the uvea	HPO Gene-Disease Associations	1.0	null
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09754
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40092
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92922
Muscle-t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
Photophobia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
Mating projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6085
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6883
PMC10896338-media-3.xlsx-GSEQ_TF_AP1_UP_DOWN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11665
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10282
placenta	HPA Tissue Gene Expression Profiles	-1.0	-0.893147
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14279
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1294
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RAB3A_KO_GDS2482_706_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047368
Vitelliform Macular Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
DC-47-KV62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201864
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63695
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
HSF1_KD_GDS1733_753_human_HeLa cells - 4 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Exudative vitreoretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.923497
Generalized Osteoarthritis	DisGeNET Gene-Disease Associations	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	66.4279
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cefepime-5761	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834611
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1259
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20339
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13071
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.007
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92285
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.02243
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.934
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4	GDSC Cell Line Gene Expression Profiles	1.0	1.93359
hsa-miR-1470	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K93800933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57894
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98222
ampicillin-1530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32284
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09851
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054332
BRD-K45185240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27209
alclometasone-5752	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26572
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22171
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995283
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4585
SLR20	DepMap CRISPR Gene Dependency	1.0	2.13394
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29376
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849383
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00532
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27947
abnormal nasal morphology	HPO Gene-Disease Associations	1.0	null
BRD-K98343273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72923
Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18217
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943653
RAB3A_Mutation - D77G point mutation_GDS2482_704_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	1.0	1.09786
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35666
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1692
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28848179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06958
PHA-00767505E-6596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21124
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0212
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93496
ciliary part	GO Cellular Component Annotations 2015	1.0	null
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95495
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19151
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.972272
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08284
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.171937
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.43758
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.745929
Vitelliform macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.423
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02001
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15998
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40295
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96008
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20179
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45314
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09595
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8839
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20857
NSUN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02265
ARID3A	ENCODE Transcription Factor Targets	1.0	null
Retinal detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825669
Blue color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053733
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.685
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064967
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50225
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2317
CRCGN010_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5767
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28682
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69355
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46569
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01967
ATXN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86719
lymphoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065682
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02677
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2348
GID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47758
LRAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39744
Nyctalopia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879653
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42509
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94366
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21054
GSE176310_1_v_0_c1qbp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.55
CHD2	ENCODE Transcription Factor Targets	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15292
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29803
JHUEM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45694
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dioxybenzone-3101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
metitepine-3231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52723
BRD-K31297909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63328
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06247
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperinsulinism	DisGeNET Gene-Disease Associations	1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.972063
PPP1CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5798
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42635
acacetin-4324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8462
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
bcor_22012066_cn_aml_lof_human_gpl570_gds4280	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.005206
TIA1_KO_GSE54418_260_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45092
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27823
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87173
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
adrenosterone-3107	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93849
vasculature development	GO Biological Process Annotations 2015	1.0	null
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.52864
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19063
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.25846
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
NRL_Deficiency_GDS1693_236_mouse_Photoreceptors cells of retinas at P2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
atypical scarring of skin	HPO Gene-Disease Associations	1.0	null
ioxaglic acid-2966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH23	DepMap CRISPR Gene Dependency	1.0	2.02992
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43721
EP300	ENCODE Transcription Factor Targets	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.83322
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38104
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94589
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.90926
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.6177
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5400-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SF295	BioGPS Cell Line Gene Expression Profiles	1.0	0.824944
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Senior-Loken syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.563
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101433
Ophthalmoplegia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K69580972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16317
Eye-retina horizontal cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0298939
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04732
sensory perception	GO Biological Process Annotations 2015	1.0	null
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72717
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91714
benperidol-4196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01198
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98016
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990628
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Keratoconus	DisGeNET Gene-Disease Associations	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tiapride-7362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998053
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye-erythroid lineage cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15219
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62708569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91507
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210718_1_v_0_shmt2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Vasculature-epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0603747
Vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13661
retinitis pigmentosa.	GAD Gene-Disease Associations	1.0	null
Small_Intestine-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834308
TP53-32428506-HUMAN-LIVER-HEPTOMA	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
late-onset retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal electroretinogram	HPO Gene-Disease Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.747
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45293
BRD-K45893504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72966
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9844
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00255
GSE249544,GSE249637_6_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Asphyxiating thoracic dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99801
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
Chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32177
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840086
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97091
SW1783	CCLE Cell Line Gene Expression Profiles	1.0	1.76627
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25727
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896847
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
variable	GeneRIF Biological Term Annotations	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48615268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05485
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH650	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51438
dapsone-5498	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K14442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91007
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834611
BRD-K13196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4415
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16919
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13056
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.76753
BRD-K25075258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28803
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.24365
CREBBP	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91215
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21233
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954024
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10901
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.825922
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16207
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
U4/U6 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046361
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50260295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11557
Lung squamous cell carcinoma_LUSC_TCGA-39-5036-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.80573
Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP2K4_knockdown_62_GSE19091	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.999056
Perturb_13008_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92319
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.866707
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36662
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13018_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.560449
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
visual field defect	HPO Gene-Disease Associations	1.0	null
Brain stem	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58739
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53921
Spinocerebellar ataxia type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
Neuronal ceroid lipofuscinosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
PF-00562151-00-5959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85074
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
GPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64885
procyclidine-4817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936526
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.62655
epicondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.685491
496100483_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.23129
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.951609
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
piromidic acid-4575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
apomorphine-1505	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45109
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12955049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55068
harmine-5855	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab5_KDM5C-KD-down_genes-Table_5_Down_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
carbamoyl phosphate synthetase i deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.17078
ATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51082
Centriolar satellite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92033
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4456	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83934572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12857
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450271
BRD-K62935726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13837
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44441
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.74013
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40134
YEATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78897
5182598-976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the nares	HPO Gene-Disease Associations	1.0	null
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
hsa-miR-1245b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-1.10247
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
DUSP26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56904
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75528
BRD-K37595074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29246
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840711
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0133
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05944
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0024
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.96
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36184
BRD-K74879991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08016
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.6907
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.48929
Pelvic Obliquity	DisGeNET Gene-Phenotype Associations	1.0	null
retinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.237706
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75177817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04123
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
rosiglitazone-1013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.284224
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67093
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26951
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053092
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.7004
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nimodipine-3103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906522
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.031
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K40228963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09729
BRD-K91810283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90077
BRD-K53720386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1781
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02006
BRD-K14098658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97018
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.00385
fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.25297
Lung adenocarcinoma_LUAD_TCGA-44-8119-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.750452
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1294	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.873
CREB1	ENCODE Transcription Factor Targets	1.0	null
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228234
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24263
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99563
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47305
MRPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87542
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Schizozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06916
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92033
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03475
GSE183316,GSE183317_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03161
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83138
LC-1F	GDSC Cell Line Gene Expression Profiles	1.0	1.42452
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36483
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88339
prazosin-5416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81175414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35123
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17181
bethanechol-3537	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye-limbal stromal cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19495
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835823
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
tested	GeneRIF Biological Term Annotations	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97129
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6651
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2072
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99836
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062901
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.7324
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Expression Profiles	-1.0	-2.44081
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84041
abnormal retinal layer morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870918
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54878
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21937
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.68888
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33984
oxprenolol-7225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48628
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54115
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80107
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18198
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840592
Perturb_2394_KD_PRKDC_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.88146
Perturb_13518_KD_ILF2_SRP077068	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.73123
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuron degeneration	MPO Gene-Phenotype Associations	1.0	null
Perturb_15983_KO_Larp7_SRP189392	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.2353
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the head	HPO Gene-Disease Associations	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30598
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02667
mode of inheritance	HPO Gene-Disease Associations	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN	DepMap CRISPR Gene Dependency	1.0	2.8703
GK_KO_GDS1555_127_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.681
BRD-K84932026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4226
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ASXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23051
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95975
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4495
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal eye morphology	MPO Gene-Phenotype Associations	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62319
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170715
BRD-K44675576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43579
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46713
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.25124
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56149
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998305
BRD-K01888220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.67536
sp1_22099172_dental_follicle_cell_gof_human_gpl11532_gse31628	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.038191
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.268
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21177
peripheral visual field loss	HPO Gene-Disease Associations	1.0	null
PMC10165825-13046_2023_2674_MOESM1_ESM.xlsx-Supplementary_Table_S7-Supplementary_Table_S7_Differential_expression_results_for_the_TEAD-TP63_directly_regulated_genes_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26951
GTEX-X261-0011-R5A-SM-3NMB4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24158
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00853706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36197
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918846
GSE165122_0_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
MTRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6867
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
GTEX-OOBK-0425-SM-3LK5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849955
CRCGN009_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24383
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymph_Node-stromal cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0854125
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28845
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0464
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0962
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046028
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.987892
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
BRD-K23333192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20778
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56735
Subpellicular microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24052
prph2	GeneRIF Biological Term Annotations	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105545
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874759
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
PHF8-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9641
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
BRD-K78365192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07899
GSE218500_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GATAD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84167
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
famotidine-5011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57094
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2119
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	2.90746
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41143
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837765
Retinitis pigmentosa	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K69453266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00235
BRD-K37975989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03729
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
retina vasculature development in camera-type eye	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17555
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68734
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946088
VEGF_A_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
TESMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89093
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02258
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.72
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC4-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.17138
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906536
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18962
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.827
BRD-K24711162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41027
Blindness	DisGeNET Gene-Phenotype Associations	1.0	null
kinetin-6813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61821
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79171
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96516
bewo	HPA Cell Line Gene Expression Profiles	-1.0	-1.66474
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARS CoV_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.07792
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.68573
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3546
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.57527
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1094
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
Hyperextension	DisGeNET Gene-Phenotype Associations	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944183
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cetirizine-2829	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.38845
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NELFE	ENCODE Transcription Factor Targets	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.96462
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
Macular Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Food vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07244
spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142909
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38382
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
ciclosporin-3267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
disorganized photoreceptor outer segment	MPO Gene-Phenotype Associations	1.0	null
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78071
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039519
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-X6-A8C5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109357
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79106
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09992
BRD-K89501960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43538
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
IGROV1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.18018
vitreous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160021
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961828
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96236
Somatotropin Deficiency	DisGeNET Gene-Disease Associations	1.0	null
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05437
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45164
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07084
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60458
BRD-K12281552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21344
Retinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40921
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.85134
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
NFYA	ENCODE Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21959
CCR4-NOT core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.116804
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9881
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58171
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90451
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
epirizole-5995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
alpha dna polymerase:primase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.503506
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858598
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77268
quinidine-5793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.215
CIAO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04757
BRD-K88962898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00277
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
Perturb_8123_KD_U2AF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.92316
BRD-K45495792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93839
ophthalmoparesis	HPO Gene-Disease Associations	1.0	null
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8585
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43579
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14547
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung-cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0897669
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52392
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methyl-salicylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78188
(+)-isoprenaline-6663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	4.45699
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07091
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21643
Type 1 diabetes mellitus_Myocardial tissue_GSE4616	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.57181
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.121
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43307
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73726
Muscular Stiffness	DisGeNET Gene-Phenotype Associations	1.0	null
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	2.18669
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5322
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97815
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14464
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23037
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6701
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.806
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esculin-3052	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K25322276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2062
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48771
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33858
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05474024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16285
Perturb_970_OE_SRSF1_SRP174924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.38361
Exoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.501
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87653
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13476
BRD-K93295557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53335
ATF2	ENCODE Transcription Factor Targets	1.0	null
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868516
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.079913
Perturb_15689_KO_Rela_SRP075924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.17488
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.27191
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28035
Prestwick-642-4594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056657
BEN	GDSC Cell Line Gene Expression Profiles	1.0	1.67244
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992376
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096886
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43991
Myalgia	DisGeNET Gene-Phenotype Associations	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.36839
biological adhesion	GO Biological Process Annotations 2015	1.0	null
GSE60367_2_v_1_cxcr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
harpagoside-4981	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0307
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.894
abnormal rod electrophysiology	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
thin retina outer nuclear layer	MGI Mouse Phenotype Associations 2023	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29754
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20279
CRCGN014_HEPG2_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22387
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61154
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97445906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06087
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38376
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56283
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90577
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29844
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7A-Table_S7A_Hippocampal_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K04544693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.55062
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912228
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4421
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04336
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.137
Perturb_13022_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18946
Conoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69191
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830337
Cataract	DisGeNET Gene-Disease Associations	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_8955_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.4567
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63663
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	3.76981
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6478
germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.081735
inner CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957766
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K73523821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62563
motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.274835
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961946
TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
Perturb_6335_KO_MLL4SET_SRP221512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.56465
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2786
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00581
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29428
PMC6664756-12915_2019_679_MOESM2_ESM.xls-Table_S7_DRGs_in_ELF1-DOX-Ensembl_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Catalytic step 1 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.57305
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
CRCGN009_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36077
abnormal retinal outer nuclear layer morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K14799424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07941
vitelliform macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.24819
Y-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
BRD-K07888312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03832
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861332
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07889
Retinitis pigmentosa 54	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.861
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05753543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59233
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
POGLUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80085
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30725
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1444
TE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.78122
GATA2_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07035171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15351
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21887
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35813
CRCGN015_MCF10A_48H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08441
BRD-K04785821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39107
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92848
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.72918
BRD-K90887068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3712
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01491
SB-202190-7054	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91864
BRD-K79627231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19176
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29555
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40452322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22911
abamectin-7218	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adult-onset night blindness	HPO Gene-Disease Associations	1.0	null
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9213
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11883
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15013
Bothnia retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.763494
BRD-K14414396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15082
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58716
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCFL	ENCODE Transcription Factor Targets	1.0	null
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-2.85645
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the fundus	HPO Gene-Disease Associations	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuron part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00253
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19995
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64859
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.505944
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.138
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71292
GTEX-X4XX-0011-R5A-SM-46MWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43901
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57781
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-2.171
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15089
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
photophobia	HPO Gene-Disease Associations	1.0	null
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13277
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26779
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.994911
substantia nigra	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
WM3211	DepMap CRISPR Gene Dependency	1.0	2.37745
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10232513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.11172
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34326
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2066
CRCGN016_MCF10A.WT.HP_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.61637
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74611
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.230245
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.376
BRD-K39978929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08262
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55315
LB771HNC	DepMap CRISPR Gene Dependency	1.0	4.21848
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43074
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143643,GSE143644_2_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phthalylsulfathiazole-3371	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLXNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41489
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thiethylperazine-5756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
leptospirosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.282582
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26632
COL4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48606
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4620-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3797
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40467
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	1.3451
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.864148
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K17063694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06141
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.7011
BRD-K37203382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0932
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.79146
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal rod electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50011
coralyne-2652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
Fhm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.07092
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20615
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31424
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950323
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478923
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5605
icSARS CoV_48Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.67396
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11386
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20201
BRD-K70979181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4661
Actin fusion focus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prestwick-664-4737	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K19100834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00605
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12752
RFX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K06177900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14311
BRD-K03542527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31346
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.91572
BRD-K25284184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47901
HCC1395	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46087
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880322
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14251637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47431
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884059
JUND	ENCODE Transcription Factor Targets	1.0	null
cyclopenthiazide-4813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02963
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87991
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.082561
josamycin-1534	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33736
growth abnormality	HPO Gene-Disease Associations	1.0	null
abnormality of the external nose	HPO Gene-Disease Associations	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834611
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6693
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14864
Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Usher syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5375
Cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
HCC70	DepMap CRISPR Gene Dependency	1.0	2.30587
Placenta	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1343
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424963
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-720	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.44037
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33896
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78403457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01992
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50377
inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227707
BRD-K04143388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70846
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.795
17683608-TableS4	GeneSigDB Published Gene Signatures	1.0	null
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48765
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
Embryonic neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.757
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62892
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.54483
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05381
tribenoside-3507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12928
BRD-K74500173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95518
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.11094
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14577
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CJM	CCLE Cell Line Gene CNV Profiles	1.0	1.43121
Oguchi disease-1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
peripheral retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.26211
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15238
SLC29A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44546
PNU-0230031-3735	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
MYC_KD_GSE22139_685_human_medulloblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KNS42	CCLE Cell Line Gene Expression Profiles	1.0	1.86045
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	168.855
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	14.7846
peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.113861
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942135
BRD-K05699155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38512
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33456
Hernia	DisGeNET Gene-Phenotype Associations	1.0	null
Macular dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.177154
BRD-K29083370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4694
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055359
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03070790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.12249
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77853
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGIF2LY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75684
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21572
GSE130401_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2834
nonmotile primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18959
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060003
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.912938
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75207
mimosine-2638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.50964
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH727	CCLE Cell Line Gene Expression Profiles	1.0	1.6907
Integrin alpha3-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
pentolonium-3676	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861276
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34215
BRD-K02204058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16417
Eye-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Idiopathic Pulmonary Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-YF-AA3L-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325701
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3447
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16856
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3724
BRD-A26165232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1438
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
probucol-4666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K66649343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35284
NCIH1836	DepMap CRISPR Gene Dependency	1.0	3.03949
COS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
GTEX-R55G-0626-SM-48FDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07256
KYM1	DepMap CRISPR Gene Dependency	1.0	3.76519
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pseudoretinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
ZNF691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4846
ASIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07602
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079213
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung-alveolar fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0799695
Occult macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
CACTIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15517
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24709
lasalocid-4985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
survival motor neuron spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.612401
HOTHC	DepMap CRISPR Gene Dependency	1.0	2.50007
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92059157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75566
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.916537
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849242
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01723566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20386
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2702
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44546
BRD-K06935782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94403
JJN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ambroxol-5319	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61599
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.617
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29234
promazine-3927	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
icSARS CoV_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.22979
MAFK	ENCODE Transcription Factor Targets	1.0	null
RBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78688
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55246
nafcillin-4103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43S-01A-21R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
BRD-K97732674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2901
PAX5	ENCODE Transcription Factor Targets	1.0	null
BRD-K36347292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12145
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9641
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2023
noscapine-7204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of the posterior segment of the eye	HPO Gene-Disease Associations	1.0	null
mitochondrial myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.195183
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.629506
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12368
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825111
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.763
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.31262
NB4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66258
camera-type eye photoreceptor cell differentiation	GO Biological Process Annotations 2015	1.0	null
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27058
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.944965
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33043
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
BRD-K25185158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36763
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39744
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63224
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07084
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65152352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24242
BRD-K57938735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05333
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046828
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14479
Photoreceptor inner segment membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.018
outer SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8438
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18474
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47213
BRD-K64860662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55576
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Eye-t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0886783
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47843
cell part	GO Cellular Component Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18511_KD_UHRF1_SRP217518	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.8421
HEMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0104
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26693
IGROV-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02895
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	3.644
Malignant mesothelioma of pleura_Pleura_GSE2549	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.38129
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69252
Nanophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
SNU489	CCLE Cell Line Gene Expression Profiles	1.0	1.45727
Polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72476
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16331
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36795
Perturb_5713_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.99642
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75002
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51913
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865361
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.639
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920464
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0383
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31586
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62968
ovary_8a	HPA Tissue Sample Gene Expression Profiles	1.0	1.23015
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11360_OE_MED19_SRP292182	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.98207
velnacrine-3292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21126
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33461
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.116804
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02913
NRBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36633
intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16286
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83443
ciprofloxacin-6700	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
flavoxate-5427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95974
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12537
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cefepime-3581	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980715
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94123
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16873
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828836
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066251
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab9_KDM5C-KD-down-DKD-rescued-Table_9_Down-regluted_genes_in_KDM5C-KD_and_rescued_genes_in_DKD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052831
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484766
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinitis pigmentosa 26	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
PMC5575985-mp2016192x4.xlsx-ST18-Unnamed_5_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18625
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994506
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
conductive hearing impairment	HPO Gene-Disease Associations	1.0	null
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11851
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68968009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44435
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26951
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68898
ZNF518B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64979
Perturb_15834_KO_Per1/Per2_SRP315583	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.7354
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77467
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04005
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97056
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17737
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF7_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
cell projection membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.003377
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920998
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4419
calcium pantothenate-4775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28203
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225395
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83676
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
Norrie disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843056
LY-294002-5213	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.05
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17429
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eye and adnexa disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36931
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37949
BRD-K04969760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09063
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05978
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839556
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28431
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.32774
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5715
photoreceptor outer segment membrane	GO Cellular Component Annotations 2015	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	3.02367
night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.626103
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77309
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865665
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54441
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03484
Perturb_16697_KO_70L02Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.34853
Midbrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Optic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
TMEM203	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3124
debrisoquine-6688	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MGH-U4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
lansoprazole-3529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26743
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.905996
CRCGN013_HEPG2_24H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27283
Erythrocytic stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886179
Retinitis pigmentosa 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13655
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00927
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.295
nortriptyline-6003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 6 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0146
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01579
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02881560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64573
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858739
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.91775
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065474
SPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48728
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86661
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22974051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04281
CRCGN012_HEPG2_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04107
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36505
BRD-K60772078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36813
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5923
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53493
RABL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25272
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8968
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.13563
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
BRD-K16207499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40219
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11389666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.1928
BRD-K71204648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05939
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.94606
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08751619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5712
Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02233
Perturb_6127_KO_NEUROD1_SRP170936	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.92218
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911168
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nemaline myopathy 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
type ii diabetes mellitus	HPO Gene-Disease Associations	1.0	null
fluphenazine-6996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC44	DepMap CRISPR Gene Dependency	1.0	2.27796
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71427
Perturb_2760_KD_CBX3_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.79003
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10191
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03627
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837358
U-118-MG	GDSC Cell Line Gene Expression Profiles	1.0	1.56742
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68804
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71341
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.769
BRD-A01717918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2928
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081964
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68025
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10896
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.76375
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.30455
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23699
eGFP-FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17536501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.31838
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01453
motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.128614
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18962
neurodegeneration	MPO Gene-Phenotype Associations	1.0	null
GSE114992,GSE114993_4_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRL_Deficiency_GDS2936_631_mouse_Retinas - 2 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50792
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14243
valproic acid-5237	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
deferoxamine-3936	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.32239
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6485
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
Retinitis pigmentosa 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.068
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89831
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86595
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63420290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82887
ZNF623	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38292
BRD-K38073091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03988
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE179031_3_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
Leber congenital amaurosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47219
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46867
DAGLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70395
SP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K49443464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64735
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967993
Lung-cd4-positive alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0897669
UQCRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9447
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79317
BRD-K47123716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13083
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936721
Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19229
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853714
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1393
Perturb_13763_KO_Uqcrq_SRP284268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.17385
Endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17286
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76493
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GSE152055_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1526-SM-4JBJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996475
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25524
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.678
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Osteoarthritis	DisGeNET Gene-Disease Associations	1.0	null
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
TAF1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5444
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20245
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102148
HCC1897	CCLE Cell Line Gene Expression Profiles	1.0	1.64538
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847062
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40883
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
TRIM21	Hub Proteins Protein-Protein Interactions	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919158
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58101
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09186
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.9864
2-aminobenzenesulfonamide-5422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1302
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18903
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02233
HNRNPA0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79512
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17178
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85387
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927141
hearing abnormality	HPO Gene-Disease Associations	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971404
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27199
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16276
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844605
ETV5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05633
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12422
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13544
Prestwick-692-4599	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cinchonidine-5833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903106
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68186
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79252
betulin-3513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.745929
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83351
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086674
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.35624
GTEX-T5JW-0226-SM-4DM7I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991681
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43256
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K93159873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21701
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41647
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.935072
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039705
clemizole-3672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40883
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2556
ZNF267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	3.33008
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37638
BRD-K34489277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28622
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56868
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.844624
abnormal retinal vasculature morphology	MPO Gene-Phenotype Associations	1.0	null
Ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04137
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54516
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24782
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83135
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86947
Perturb_15807_KO_Chop_SRP350242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bietti crystalline corneoretinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
clenbuterol-3228	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80881
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Glaucoma_Retina_GSE3554	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.24473
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.52134
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63441
EGR1	ChEA Transcription Factor Targets	1.0	null
neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.365633
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065174
BRD-K45010872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44084
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970264
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.79191
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.182
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67055
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.135
hsa-miR-3074-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19444
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
Hyalocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67954
BRD-K36045097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33386
BRD-K41492504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48122
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29676
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948588
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26721
propidium iodide-6104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68926
C1orf116	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82576
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10823
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.2895
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.946125
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57666
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49891
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LN18	CCLE Cell Line Gene Expression Profiles	1.0	1.70997
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06107
CRCGN010_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29392
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055655
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.827254
PGAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98235
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.717655
TCF3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37585
Mammary-pericyte cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
photoreceptor cell differentiation	GO Biological Process Annotations 2015	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.85162
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20802
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52646
15297395-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47229
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74963
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92617
BRD-K14383477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32095
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6995
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.916
Perturb_9955_KD_SF1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.0123
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04723
GLB1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09775
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17918
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88723
GSE178714_1_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14896_KO_H13_ERP118037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.43623
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79081
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969268
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24608
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26913
TOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3018
retinal degeneration	MPO Gene-Phenotype Associations	1.0	null
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PCBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15761
BRD-K18142082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24039
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6051
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46575
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28549
abnormality of the retinal pigment epithelium	HPO Gene-Disease Associations	1.0	null
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
Agnosia	DisGeNET Gene-Disease Associations	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mammary-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
Distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.637
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5868
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dextromethorphan-5401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40295
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.159268
BRD-K97052218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24206
BRD-K50596260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19894
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1138
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072407
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08885
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4073
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65311
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40295
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	2.05459
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell projection membrane	GO Cellular Component Annotations 2015	1.0	null
thioproperazine-6265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Seckel syndrome 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51008
phenotype	GeneRIF Biological Term Annotations	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.4045
ZCCHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21933
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900616
Perturb_11534_KD_THOR_SRP121007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.96941
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08037
KDM5B	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYCN	ChEA Transcription Factor Targets	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85785
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acquired color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
short photoreceptor outer segment	MGI Mouse Phenotype Associations 2023	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.354355
trimipramine-4163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07003
ethotoin-3809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KATNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04134
E2F6	JASPAR Predicted Transcription Factor Targets	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.514
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22931
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846737
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11914
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02349
C16orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05009
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097317
MYCN-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05595
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62328
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
fluvastatin-6691	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0806
Campomelic Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06458
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09155
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4926
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9012
Rhabdomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dinoprostone-6586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSU	DepMap CRISPR Gene Dependency	1.0	4.05219
showing	GeneRIF Biological Term Annotations	1.0	null
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59844
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86322
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26463
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889843
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kinesin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.447
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alstrom syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Lung squamous cell carcinoma_LUSC_TCGA-66-2773-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Interphotoreceptor matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.983
BRD-K21059010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22026
PTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91041
CHAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96183
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22498
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KINGS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.72806
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82456
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942264
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of circulating hormone level	HPO Gene-Disease Associations	1.0	null
flunisolide-6023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9003
organelle part	GO Cellular Component Annotations 2015	1.0	null
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.15884
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9135
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61215
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.612
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33661
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11871
MAZ	ENCODE Transcription Factor Targets	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33039
BCB000038-7516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
CD177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56563
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06481
Membrane stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.397
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
mecamylamine-7023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0922
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.37545
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29525414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4879
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27058632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01847
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98339
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7035
hypoplastic male external genitalia	HPO Gene-Disease Associations	1.0	null
BSPRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82643
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32114
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3429
anteverted nares	HPO Gene-Disease Associations	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
FLAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56376
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.908781
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77026
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860344
ANKRD16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85327
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981406
BRD-K01991250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77046
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nalidixic acid-3668	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21624
Idiopathic Osteoarthritis	DisGeNET Gene-Disease Associations	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Type III intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.145
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20973
abnormal photoreceptor outer segment morphology	MPO Gene-Phenotype Associations	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157282_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP4B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83632
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31003
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00416
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.201962
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3739
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49417
GSE249544,GSE249637_6_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03179
hsa-miR-627	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77099
Retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.533
Coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22988
photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.745025
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36357
minaprine-4814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.033
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.08319
photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.389296
dipyridamole-4656	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K26351062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24573
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62684
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	163.389
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867881
BRD-K17144037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49584
sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARNT::HIF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2212
CMTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39448
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.13866
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80069
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56947
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42955
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
Vitreous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7537
PMC120784__F8	PFOCR Pathway Figure Associations 2024	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19128
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20657
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04017
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27691
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27907
BRD-K44613656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35721
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.231911
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
BRD-K29662535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59192
flupentixol-2643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9998
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58135
nystagmus	HPO Gene-Disease Associations	1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39456
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-00-IL62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223071
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	1.87415
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
BRD-K68758594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02793
Zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
Congenital stationary night blindness autosomal dominant 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab7_TRIM11-KD-down_genes-Table_7_Down-regulated_genes_in_TRIM11-KD_TRIM11-KD1_Control_overlap_TRIM11-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92887
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841341
BRD-K17239874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24035
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Perturb_7179_KO_TrEx_SRP163035	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.45829
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34167
BRD-K43719900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24203
Perturb_7065_OE|KO_Hdac|Eed_SRP092655	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64586
NABP1	Hub Proteins Protein-Protein Interactions	1.0	null
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11225
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52071
all	HPO Gene-Disease Associations	1.0	null
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
Holoprosencephaly 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.507
BRD-K01311880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77346
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
ANXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05329
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53993775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13518
GSE99187_1_v_0_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858796
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.51945
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02965
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60394
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.28849
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.805
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78893
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.003506
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21054
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33967062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38121
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1202
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259473
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40295
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847152
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19147
E2F6	ENCODE Transcription Factor Targets	1.0	null
BRD-K52157065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42357
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16357
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34553
Kidney Chromophobe_KICH_TCGA-KO-8415-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.5319
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63317
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4721
Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06459
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66539236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43172
abnormality of the vasculature of the eye	HPO Gene-Disease Associations	1.0	null
TAL1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18609
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell differentiation	GO Biological Process Annotations 2015	1.0	null
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00617
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8948659-ADVS-9-2104491-s013.xlsx-Sheet1-Supplemental_Table_9_related_to_Figure_7_Differential_genes_highly_correlated_with_TP53_deletion_in_H929_cells_by_RNA-seq_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.316406
NDUFB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32546
Perturb_2584_KD_CEBPD_SRP059191	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6155
diclofenac-2756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SB-202190-6887	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NFE2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GW-8510-7080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46659
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PELI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58757
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17617_KO_TIP60_SRP386872	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.18081
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0511
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828003
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.1658
Flexion Contracture - Elbow	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07084
retinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.80563
estradiol-7000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K04143779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.69802
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.007
BRD-K31325635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13032
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15979
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.893328
BRD-K00414849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25725
BRD-K35860167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35247
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60628
gyrate atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00879
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94904
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061664
hyperreflexia	HPO Gene-Disease Associations	1.0	null
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.404
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08094
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.39254
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4862
Retinitis pigmentosa 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.436
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6334985__F7	PFOCR Pathway Figure Associations 2024	1.0	null
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47611
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
oxolamine-3344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
ga88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08779
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62226454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02872
ZBTB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35796
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28531276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14042
Perturb_11973_KO_Soat1_SRP235547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.94478
Retinitis pigmentosa 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2196	GDSC Cell Line Gene Expression Profiles	1.0	1.97007
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23979
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24671
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30055
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54109
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.26899
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17058
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55736
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828089
JURKAT	DepMap CRISPR Gene Dependency	1.0	4.99646
BRD-K73025852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04417
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13698
ZMYND19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99101
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11342
system process	GO Biological Process Annotations 2015	1.0	null
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05018
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14245
ITSN1	Pathway Commons Protein-Protein Interactions	1.0	null
GMCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81351
Eye disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
BRD-K39809702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53309
azaperone-6151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26587
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36338
MKNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905754
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04648
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203604
SHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18303
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33386
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80963
Ocular albinism 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
H6PD_KO_GDS3195_603_mouse_Skeletal muscle - Tibialis anterior	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K33151492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09996
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59741
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.53811
Brain Lower Grade Glioma_LGG_TCGA-TM-A84F-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31416
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
trichostatin A-3332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K38719699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07963
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33607
MOLP8	CCLE Cell Line Gene CNV Profiles	1.0	1.50343
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09392
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_2079_KD_ZFC3H1_SRP322699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.55526
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19469
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14313
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81725
piperacillin-3420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
Lymph_Node-cd141-positive myeloid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
GSE77795_0_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71769
GTPBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21053
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32782
abnormal retinal rod cell morphology	MPO Gene-Phenotype Associations	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
BRD-K18409585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34837
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88590066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81559
diphemanil metilsulfate-4591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978257
PPP1R16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64018
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.02641
GPR107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25223
Elbow Stiff	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28107
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retinal diseases	GAD Gene-Disease Associations	1.0	null
Optic atrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	2.14841
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.161
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70171
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Visual Field Constriction	DisGeNET Gene-Phenotype Associations	1.0	null
TYW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20929
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
Perturb_9185_OE_ZNF593AS_SRP298754	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.08679
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.21145
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23411
tretinoin-6931	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
0316684-0000-7052	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40883
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888374
Lung-pulmonary ionocyte	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
CRCGN014_HEPG2_3H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32235
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89568
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9645_KO_HES7_SRP153047	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.65005
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95112
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00869
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33456
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14013
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21515
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
Rosette	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14942405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53004
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Autosomal dominant vitreoretinochoroidopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18943
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thiamazole-3432	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09394
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04948
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.914116
PMC8322331-41598_2021_94805_MOESM3_ESM.xlsx-b_STAT3_UP_assoc_transcripts-Gene_Name_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43007
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07852
MKN45	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52591
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51468
CRCGN015_MCF10A_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.90795
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.51399
age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.192031
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33587
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0695
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36214
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exudative vitreoretinopathy 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.072
Esophagus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.90137
Perturb_13010_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN014_HEPG2_3H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.562
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinitis pigmentosa 87	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16136897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95338
abnormality of the optic nerve	HPO Gene-Disease Associations	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1437
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4665
GSE237040_0_v_3_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50557
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.509813
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906092
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
kinetin-4477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39562
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18005
levobunolol-3354	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21344
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113639
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32101
branch retinal artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.926279
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28477
PNU-0230031-3732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882553
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50853
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.323075
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.967626
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K36397874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6619
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98876
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10-methoxyharmalan-2893	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
eye	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Fever	DisGeNET Gene-Phenotype Associations	1.0	null
CAL-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62029
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07294
ZNF143	ENCODE Transcription Factor Targets	1.0	null
BRD-K18332967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26847
NRBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37288
Thymus-immature natural killer cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971579
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79497
BRD-A17831693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28986
PMC6334985__F7	PFOCR Pathway Figure Associations 2023	1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78849
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.79204
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53339
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14927
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41306
HSC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.79762
ZNF525	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59809
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.853535
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the lens	HPO Gene-Disease Associations	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24356
ciliary part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.42575
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.475
BRD-K44133102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6176
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838184
Perturb_13452_KO_Coro1_SRP168748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.21247
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47O-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67604
indoprofen-4249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26185
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39067
Perturb_13736_OE_MYCL_SRP277794	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.16092
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6349
Perturb_9_OE_ERG/MYC_SRP069177	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.44494
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.163
Tongue-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0886783
METTL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41421
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21922
core part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14166
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04683
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838973
SR-95639A-3272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VMRCLCD	CCLE Cell Line Gene Expression Profiles	1.0	2.08184
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.4316
SRF	ENCODE Transcription Factor Targets	1.0	null
Hallux Valgus	DisGeNET Gene-Disease Associations	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01856
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dirithromycin-2863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.266
retinitis pigmentosa 7, digenic	OMIM Gene-Disease Associations	1.0	null
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
HUES64_Cell_Line	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03573
BRD-K23164928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11168
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925563
ZNF782	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18185
picotamide-6787	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39494
bumetanide-5542	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854963
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13299
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.84286
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13238
CORO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09353
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.00977
17555561-Table1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K88812688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46638
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ifosfamide-6279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K37657049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05096
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0425
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.5914
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72289
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62942
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86285
BRD-K24453679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47813
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935257
TAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80961
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
CAPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06757
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877477
TRAPPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45967
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76047
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D-423MG	GDSC Cell Line Gene Expression Profiles	-1.0	-2.13775
CRCGN013_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57153
KNS-42	GDSC Cell Line Gene Expression Profiles	1.0	1.99817
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28311
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65526
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065701
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01454
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413532
DA-33-BM26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267547
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2976
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
micronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157943
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926502
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.96272
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42339
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61844
SBK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78336
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EO-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93334
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01332
GATA1_G1E-ER4_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sirolimus-6180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0691
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.373
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3851
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92023
KLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35138
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.387
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.19481
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.216
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88097
BRD-K16496880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47045
PTGES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83307
Charcot-Marie-Tooth Disease	DisGeNET Gene-Disease Associations	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.4522
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15104
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.14664
Retinitis pigmentosa 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5097
Leaf epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.579
Lateral cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28362
Capitate projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07777
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72822
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80899
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.65889
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07929
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052044
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064041
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
APPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87836
KGN cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
globe disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.572162
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.822
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.18939
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63887881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9145
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
fulvestrant-5926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.36727
BRD-K49664555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11797
diabetes mellitus	HPO Gene-Disease Associations	1.0	null
GSE186647,GSE217288_1_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.987411
X-linked atrophic macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
BSX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07084
BRD-K05877335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14615
cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.370121
GSE221577_1_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K04195898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50222
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42307
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTA3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47709
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849971
death-inducing signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
CD320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99887
fusaric acid-4105	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37336973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11328
Perturb_6428_KD_ADAR1_SRP009659	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12086
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24071
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910958
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25772
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949983
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71427
BRD-K88190816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31188
Bilirubin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9054
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059747
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910461
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171286
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68897
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64823
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63481
WWC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67985
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0726-SM-4DXUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840616
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4941
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53949
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_HEPG2_48H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63571
FOSL2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61137
Leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
BRD-K72709319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12694
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24272
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33896
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15255
photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.256197
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1196
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14837
Vasculature-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0919441
vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
GABPA	ENCODE Transcription Factor Targets	1.0	null
cone-rod dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83528
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83546
Perturb_2762_KD_BRG1_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.65177
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7866
Perturb_2035_KO_Pth1r_SRP341470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.3778
HCFC1	ENCODE Transcription Factor Targets	1.0	null
LB831-BLC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.59135
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44594
MEF2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952094
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SF539	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32466
Blood-naive thymus-derived cd4-positive, alpha-beta t cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0908555
NB13	DepMap CRISPR Gene Dependency	1.0	3.91637
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696