association dataset threshold value standardized value Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IRF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17794 GTEX-RU72-1126-SM-2TF6H GTEx Tissue Sample Gene Expression Profiles 1.0 1.42279 GTEX-WRHK-1426-SM-3MJF9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08501 PGBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3781 SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.87778 496100417_HIP_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.79915 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null oviduct TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.578816 Ectoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.7 GSE213228_1_v_5_irak2_human RummaGEO Gene Perturbation Signatures 1.0 null EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.5305 rostral presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10545 MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 nucleus GO Cellular Component Annotations 2015 1.0 null MEIS3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9374 HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40471 CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TGIF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.1486 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99353 GTEX-W5X1-2826-SM-3GILM GTEx Tissue Sample Gene Expression Profiles 1.0 1.27881 MAEA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3962 SKMEL1 CCLE Cell Line Gene Expression Profiles 1.0 1.60531 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TE10 CCLE Cell Line Gene Expression Profiles -1.0 -2.05914 GTEX-XYKS-2526-SM-4BOPX GTEx Tissue Sample Gene Expression Profiles 1.0 1.42683 HH CCLE Cell Line Gene Expression Profiles -1.0 -1.5096 NOS1 DepMap CRISPR Gene Dependency 1.0 3.49984 RBM34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18577 SELENOF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24268 GTEX-U3ZM-1526-SM-3DB9D GTEx Tissue Sample Gene Expression Profiles 1.0 1.08351 kill GeneRIF Biological Term Annotations 1.0 null IRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82794 SP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77759 COLO800 CCLE Cell Line Gene Expression Profiles 1.0 2.13446 GTEX-UPK5-0426-SM-3GAEK GTEx Tissue Sample Gene Expression Profiles 1.0 1.38932 salivary gland adenoid cystic carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.752492 Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65575 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.2794 BET1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62185 olfactory tubercle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83413 Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null uterus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074322 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null against GeneRIF Biological Term Annotations 1.0 null posterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.940085 sperm GeneRIF Biological Term Annotations 1.0 null cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22722 MTRF1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47325 ARFGAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4014 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YW-0126-SM-3LK6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.968589 rostral putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08145 Ciliary plasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.262 PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC Rummagene Transcription Factor Associations 2026 1.0 null Calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.039 CERS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57571 SHISAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63327 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16865 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MM383 DepMap CRISPR Gene Dependency 1.0 4.53701 Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null U2AF1L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06644 FOXP1 ChEA Transcription Factor Targets 1.0 null GSE175787_8_v_7_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25796 CAPRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06399 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.896011 regulation of phosphorylation GO Biological Process Annotations 2023 1.0 null inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19072 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.79869 protein binding GO Molecular Function Annotations 2015 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.924802 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044927 PIANP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17717 Primary ciliary dyskinesia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.408 all GWASdb SNP-Phenotype Associations 1.0 0.032401 Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Megagametophyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.061 Prostate adenocarcinoma_PRAD_TCGA-J4-A6M7-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sertoli cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.511 GTEX-XYKS-2726-SM-4E3IC GTEx Tissue Sample Gene Expression Profiles 1.0 0.826934 RFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05043 SJSA1 CCLE Cell Line Gene Expression Profiles -1.0 -1.90187 NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -1.59931 PMC11161988-12906_2024_4523_MOESM3_ESM.pdf-63-FOXD1_FOXD1 Rummagene Transcription Factor Associations 2026 1.0 null mammalian phenotype MPO Gene-Phenotype Associations 1.0 null GTEX-RWS6-1926-SM-47JXY GTEx Tissue Sample Gene Expression Profiles 1.0 1.29167 flagella GeneRIF Biological Term Annotations 1.0 null GSE213588_10_v_5_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Intraciliary transport particle A COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.178 Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.5862 SUM149PT DepMap CRISPR Gene Dependency 1.0 2.57055 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7052 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF Rummagene Transcription Factor Associations 2026 1.0 null FHOD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37771 epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060139 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 CENPQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82082 motile cilium GO Cellular Component Annotations 2023 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.322 TMSB4X CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83614 TUHR10TKB CCLE Cell Line Gene CNV Profiles -1.0 -1.77649 Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.087 hippocampus HPA Tissue Protein Expression Profiles -1.0 -1.03402 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE210655_3_v_5_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null VAMP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52857 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.645 Branch TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.844 TRIM25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19522 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.651299 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.80393 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF451 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63515 principal GeneRIF Biological Term Annotations 1.0 null bone marrow HPA Tissue Gene Expression Profiles -1.0 -0.861535 generate GeneRIF Biological Term Annotations 1.0 null Testicular germ cell cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.123 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.599 EIF2AK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80688 ZNF789 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94978 SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 KYSE180 CCLE Cell Line Gene CNV Profiles 1.0 1.87601 Germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.111 MAFA MotifMap Predicted Transcription Factor Targets 1.0 null MEF2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71949 REST ChEA Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2J2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14048 TRIL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92216 SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940846 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984957 H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null reproductive system phenotype MPO Gene-Phenotype Associations 1.0 null OSBPL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65349 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Oviduct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.26 GTEX-QLQW-0426-SM-447A7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.899471 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 Disorder of sexual development DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.246 GTEX-N7MS-0225-SM-4E3HO GTEx Tissue Sample Gene Expression Profiles 1.0 1.34685 RELB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9158 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HW-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.877218 HCC1419 DepMap CRISPR Gene Dependency 1.0 2.25973 8MGBA DepMap CRISPR Gene Dependency 1.0 2.49418 Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral tuberal nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.942986 HO1U1 DepMap CRISPR Gene Dependency 1.0 3.36418 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.54518 RAB33B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11228 GSE236486_1_v_2_arnt_human RummaGEO Gene Perturbation Signatures 1.0 null BOD1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65882 ERBB2_knockdown_235_GSE8373 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.0128 growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.569663 Gametophyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.017 PKNOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 76.6931 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.902952 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00851 Primary cell wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.839 CRELD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15538 KYSE270 CCLE Cell Line Gene CNV Profiles 1.0 2.24459 Awn TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.393 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.80763 Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RSPO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61179 NCIH747 CCLE Cell Line Gene CNV Profiles 1.0 1.49994 MAL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62474 outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.03629 H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-1226-SM-4GICG GTEx Tissue Sample Gene Expression Profiles 1.0 1.38032 SIN3B-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NRDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15456 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.771 CREB3L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.8764 SNAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1185 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 2.0073 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.53763 inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12067 Cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.768 NCIH1568 CCLE Cell Line Gene Expression Profiles -1.0 -1.79274 abnormal male reproductive system physiology MPO Gene-Phenotype Associations 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053473 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.7231 FES CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86586 MFAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9641 respiratory system disease GWASdb SNP-Disease Associations 1.0 0.203852 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.08232 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Mandibular organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.98 PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94666 GTEX-XUJ4-1826-SM-4BOOU GTEx Tissue Sample Gene Expression Profiles 1.0 0.9215 9+2 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.644 Secretory granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.712 GTEX-XQ8I-0426-SM-4BOPO GTEx Tissue Sample Gene Expression Profiles 1.0 1.14667 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.875115 immunogenicity GeneRIF Biological Term Annotations 1.0 null Ebf4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 41.4965 breast GTEx Tissue Gene Expression Profiles 1.0 1.85305 CYC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16431 Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2429 DepMap CRISPR Gene Dependency 1.0 2.54316 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MELHO CCLE Cell Line Gene Expression Profiles 1.0 1.70795 ZNF883 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78362 mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.2257 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47357 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.611346 PRRC2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43409 Corpus epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.55 Ovum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.107 ZBTB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59567 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 3.3398 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48682 CLPP_KO_GDS4791_537_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MDAMB435S CCLE Cell Line Gene Expression Profiles 1.0 1.61693 HES5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89607 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041086 RCOR3 ChEA Transcription Factor Targets 1.0 null H2AX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96163 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066402 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.942 WM115 DepMap CRISPR Gene Dependency 1.0 3.02746 GSE216043_10_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GSE224479_0_v_1_ino80_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X638-0426-SM-47JY2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17359 GTEX-R3RS-0626-SM-48FE1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16345 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Male infertility due to globozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.652 ZNF98 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70537 FU97 CCLE Cell Line Gene Expression Profiles -1.0 -1.80829 19204204-SupplementaryTable1 GeneSigDB Published Gene Signatures 1.0 null lingual gyrus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13704 496100414_TCx_probable Alzheimer's disease_no TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.35816 TAF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70613 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral ventricle HPA Tissue Protein Expression Profiles -1.0 -1.03402 GTEX-WH7G-2026-SM-3NMBL GTEx Tissue Sample Gene Expression Profiles 1.0 1.13558 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39296 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.991631 sh-sy5y cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.506672 RDES CCLE Cell Line Gene CNV Profiles -1.0 -1.38229 RCOR3-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spermatogonium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.562 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040584 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WXYG-2326-SM-4E3I6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02046 POGLUT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26761 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043641 ADCY7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32875 HGC27 CCLE Cell Line Gene CNV Profiles -1.0 -1.44263 Bacterial Infection_Leukocyte - Monocyte - Macrophage (MMHCC)_GSE6435 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.03196 APH1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46543 Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84825 Chromatoid body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.709 POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAPK13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61472 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cytotoxic GeneRIF Biological Term Annotations 1.0 null PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8II-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Zona pellucida receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.35 Multiple myeloma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.336 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.75912 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861636 DENND4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57904 CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.457 only GeneRIF Biological Term Annotations 1.0 null GTEX-UJMC-1926-SM-3GADS GTEx Tissue Sample Gene Expression Profiles 1.0 1.28945 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.971307 CDX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.2407 GSE230354_0_v_1_rheb_mouse RummaGEO Gene Perturbation Signatures -1.0 null ML1 CCLE Cell Line Gene CNV Profiles -1.0 -1.45718 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22941 DPYSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85741 RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07673 ZNF888 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85427 orbital frontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10056 DDX42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37235 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32305 JUN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43524 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bone marrow disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.253 DRGX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42145 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ITPRIPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07869 A101D CCLE Cell Line Gene Expression Profiles 1.0 1.61491 Ischemic Stroke DisGeNET Gene-Disease Associations 1.0 null Opisthorchiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.618 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ERCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67397 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22761 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.36922 GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 2.03643 male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.03975 PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.92068 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.64035 COA7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0397 outer SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00039 GTEX-U4B1-1126-SM-4DXV3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1057 NDRG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53593 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052657 Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM168B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7005 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.84137 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14709 YAP1-20516196-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null C13orf42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42391 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.461078 RO60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66146 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4467679-12967_2015_546_MOESM3_ESM.csv--TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052004 LU99 DepMap CRISPR Gene Dependency 1.0 2.98498 Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Secondary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.998 titer GeneRIF Biological Term Annotations 1.0 null cilium GO Cellular Component Annotations 2025 1.0 null THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.1582 regulation of protein phosphorylation GO Biological Process Annotations 2025 1.0 null Sperm annulus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.844 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE206516,GSE206518_0_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures 1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28926 HT144SKINFV2 DepMap CRISPR Gene Dependency 1.0 2.34538 hsa-miR-3613-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.98881 Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072778 MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6072 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20026 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4621-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEL270 DepMap CRISPR Gene Dependency 1.0 3.02874 promising GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JS-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.856663 CREB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9077 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Axoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.262 PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null Urethral syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.208 RBM43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28695 Epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.792 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063293 KDM2B-26808549-CHIP-SEQ-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 hosts GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RU72-0626-SM-46MUI GTEx Tissue Sample Gene Expression Profiles 1.0 1.3932 ZNF766 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43293 H3K27me3_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PQ-0126-SM-2S1NM GTEx Tissue Sample Gene Expression Profiles 1.0 0.860757 PLEKHA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3843 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A0VS-01A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU626 CCLE Cell Line Gene CNV Profiles -1.0 -1.358 U-698-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07529 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_Fetal Heart Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.81743 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07848 Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sc TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.791 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.01151 POR_KO_GDS1678_760_mouse_Colon GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null 496100658_FWM_probable Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.39823 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Mdr2_KO_GDS1990_285_mouse_Livers of 3 month old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null spleen HPA Tissue Protein Expression Profiles -1.0 -1.03402 Synaptonemal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.795 KLF16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56818 GTEX-X4EP-2926-SM-3P5YQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.03229 PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC2-SYMBOL_ONECUT2 Rummagene Transcription Factor Associations 2026 1.0 null reduced male fertility MPO Gene-Phenotype Associations 1.0 null CAL33 DepMap CRISPR Gene Dependency 1.0 4.70168 translation GeneRIF Biological Term Annotations 1.0 null ezetimibe_mus musculus_gpl2995_gse39813 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null EFEMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50445 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMZS-0126-SM-3DB9Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.03281 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null HEC1B CCLE Cell Line Gene CNV Profiles 1.0 1.34657 GTEX-VUSG-2326-SM-4KL1U GTEx Tissue Sample Gene Expression Profiles 1.0 1.08696 ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0625 inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2696 GTEX-XUYS-0126-SM-47JWZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.907912 DNASE1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56096 Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-Q2AG-0326-SM-48U1O GTEx Tissue Sample Gene Expression Profiles 1.0 1.32533 GTEX-WHWD-1826-SM-3LK6I GTEx Tissue Sample Gene Expression Profiles 1.0 0.989864 MOPC-315 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.936 SMIM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24732 PMC5830929-supp_gad.301887.117_Supplemental_Table_S3.xlsx-Sheet1-Upregulated_genes_in_CHD7-KD_and_CHARGE_NE_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08066 GTEX-QCQG-1626-SM-48U26 GTEx Tissue Sample Gene Expression Profiles 1.0 0.980809 ZKSCAN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.3286 UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02985 one GeneRIF Biological Term Annotations 1.0 null GTEX-X3Y1-2426-SM-3P5Z7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36163 Digestive cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.548 GTEX-OXRK-1726-SM-3NB16 GTEx Tissue Sample Gene Expression Profiles 1.0 0.901683 skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062304 Heschl's gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16969 ZBED4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86544 normozoospermic GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Seminal vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.134 SMSCTR DepMap CRISPR Gene Dependency 1.0 2.6263 SPI1 ENCODE Transcription Factor Targets 1.0 null NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63914 axoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.519389 inner CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27479 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-1293 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Outer dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.571 H3K27me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null overnutrition GWASdb SNP-Disease Associations 1.0 0.437961 ECE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.62606 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07738 GTEX-U8XE-0326-SM-3DB8P GTEx Tissue Sample Gene Expression Profiles 1.0 0.96948 Perturb_12644_KD_SIRT5_SRP311327 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3236 PPIH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89792 RNF167 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47629 GTEX-WOFL-0126-SM-3MJG2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.963694 deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.870383 small intestine HPA Tissue Protein Expression Profiles 1.0 1.0705 GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null cilium organization GO Biological Process Annotations 2023 1.0 null Megasporangium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.057 central gray of the pons, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01341 TBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.6963 SUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43833 Acrosomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.465 CARNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79548 KDM3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19628 KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X15G-1626-SM-3NMB3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25366 Spermatid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.145 male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 GSE191105_0_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF MotifMap Predicted Transcription Factor Targets 1.0 null 496100652_PCx_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.09409 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26577 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of phosphorylation GO Biological Process Annotations 2025 1.0 null NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5312 GTEX-T8EM-1026-SM-3DB7M GTEx Tissue Sample Gene Expression Profiles 1.0 0.894967 B800-820 antenna complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.615 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-50-5930-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7818 Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07347 EIF4EBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82517 pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.855269 GTEX-WFG7-1526-SM-4LVMG GTEx Tissue Sample Gene Expression Profiles 1.0 1.15289 SSTR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42923 CILP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68263 SARS-BatSRBD_24Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.78904 Varicocele DisGeNET Gene-Disease Associations 1.0 null KLF7_01_342 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.46534 PCGF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87188 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-W5WG-1826-SM-4KL2Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.827255 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.58696 cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.845419 frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.898516 GTEX-T6MO-1626-SM-32QOM GTEx Tissue Sample Gene Expression Profiles 1.0 0.896306 skmel30 HPA Cell Line Gene Expression Profiles 1.0 1.1558 PIWIL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84481 CCDC78 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62649 TP53-20018659-R1E-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.882102 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-2426-SM-4BOO3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.852247 SMARCA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80689 LATS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4429 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.452 ZCCHC8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00722 premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6074 UBR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81305 occipital pole, left, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.40079 SPRYD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11959 obstructive lung disease GWASdb SNP-Phenotype Associations 1.0 0.381963 RMND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51445 Radial spoke head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.483 TCF7 ChEA Transcription Factor Targets 1.0 null male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PHF5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60161 C12orf4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54344 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -1.90252 Female accessory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.881 CYCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50858 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.46902 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SP100_01_82 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.38834 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08731 GTEX-XOTO-0126-SM-4B66N GTEx Tissue Sample Gene Expression Profiles 1.0 0.933218 Perturb_17268_KO_Sox30_SRP139811 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 head of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12795 A673 CCLE Cell Line Gene Expression Profiles -1.0 -3.00103 A4/FUK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.991631 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SF-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.7559 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.942627 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6932 mainolfactoryepithelium.MOE. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.58028 NME3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59519 PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null Myeloid neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.278 EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sperm principal piece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.039 gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29M-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPTXR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2339 SPI1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM83D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54705 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32313 immunotherapy GeneRIF Biological Term Annotations 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.939749 Radial spoke stalk COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.796 MYO1C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85119 Household income GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0 Wt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 73.9241 GSE152246_0_v_1_dihydrotestosterone_human RummaGEO Drug Perturbation Signatures -1.0 null UBB_KO_GDS3906_496_mouse_Testis - 28 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COR-L279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.63914 dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.69872 upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.63481 antigen GeneRIF Biological Term Annotations 1.0 null GTEX-POMQ-2026-SM-2S1OD GTEx Tissue Sample Gene Expression Profiles 1.0 1.23789 dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19786 Hepatic Cirrhosis_Liver_GSE6764 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.67395 Plant ovule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.056 Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF580 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47541 HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XQ3S-1526-SM-4BOOC GTEx Tissue Sample Gene Expression Profiles 1.0 1.05061 Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chaperonin-containing T-complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.738 Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.44792 PPM1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36129 GR MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_5_v_6_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.888486 primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.47514 CLPP_KO_GSE40207_392_mouse_Testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null OVCA 429 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.80317 ZNF586 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13583 TUBA1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.92201 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984957 EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0953 Household income (MTAG) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60924 RHO GTPase Effectors Reactome Pathways 2024 1.0 null GSE143782_3_v_4_calcitriol_human RummaGEO Drug Perturbation Signatures -1.0 null TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4737 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCIH1105 CCLE Cell Line Gene CNV Profiles 1.0 2.17864 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.48932 RBBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77478 GSE191105_2_v_4_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE ChEA Transcription Factor Targets 2022 1.0 null intergenic GeneRIF Biological Term Annotations 1.0 null SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null another GeneRIF Biological Term Annotations 1.0 null domaincontaining GeneRIF Biological Term Annotations 1.0 null Perinuclear region of cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.766 BRI3BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59069 BAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05322 STAT1_01_83 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.64119 LTBR_INHIBITION - 1 Day_GDS2004_733_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NANOG-16518401-CHIP-PET-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE202825_2_v_1_ano1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-W5WG-2426-SM-4LMI6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.904409 AMPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55921 OGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61438 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.7722 KCNA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9602 POLR2A ENCODE Transcription Factor Targets 1.0 null hippocampus (hippocampal formation)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18381 Signaling by Rho GTPases, Miro GTPases and RHOBTB3 Reactome Pathways 2024 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.71256 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.22845 H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELK4 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.57929 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07254 CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null prostate HPA Tissue Protein Expression Profiles -1.0 -1.03402 RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-S7PM-0126-SM-4AD6S GTEx Tissue Sample Gene Expression Profiles 1.0 0.98427 ARHGEF10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9888 ZNF224 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62402 RPS20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51368 GTEX-WHPG-2626-SM-3NMBR GTEx Tissue Sample Gene Expression Profiles 1.0 0.95106 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38607 Uterine Carcinosarcoma_UCS_TCGA-ND-A4WA-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.3933 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.7892 plasma membrane bounded cell projection organization GO Biological Process Annotations 2023 1.0 null GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.09749 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1632 MZT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55249 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.931494 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.766097 parathyroid gland HPA Tissue Protein Expression Profiles -1.0 -1.03402 abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.119383 cilium organization GO Biological Process Annotations 2025 1.0 null GTEX-X4XY-0226-SM-4E3IZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.897748 USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null duodenum HPA Tissue Protein Expression Profiles 1.0 1.0705 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.4073 GSE110268_1_v_3_foxd1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC11464544-41467_2024_52946_MOESM10_ESM.xlsx-p64-markers-Supplementary_Data_7_Marker_genes_for_schwann_cell_subclusters_TCF12 Rummagene Transcription Factor Associations 2026 1.0 null TMEM106B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7075 GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures -1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.52639 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MRPL15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72006 salivary gland carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.251542 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WZTO-0126-SM-3NM95 GTEx Tissue Sample Gene Expression Profiles 1.0 0.954142 GTEX-PLZ5-1126-SM-3P613 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06809 GSE164494_1_v_2_rab22a_mouse RummaGEO Gene Perturbation Signatures -1.0 null Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.0296 mRNA_ID1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7652-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963772 substantia nigra, compact part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896701 KG1 CCLE Cell Line Gene Expression Profiles -1.0 -2.45219 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MIX23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66186 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23157 Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null suggesting GeneRIF Biological Term Annotations 1.0 null gallbladder HPA Tissue Gene Expression Profiles -1.0 -0.861535 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36705 Spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.719 MRPL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32265 Leydig cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.282 Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33094 GTEX-PWO3-1526-SM-48TCM GTEx Tissue Sample Gene Expression Profiles 1.0 0.946414 Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17539 LDHA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70549 496100465_HIP_possible Alzheimer's disease_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.1299 Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDY2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89653 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null asthenozoospermia MPO Gene-Phenotype Associations 1.0 null HCC2185 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.628198 GTEX-XUJ4-2026-SM-4BOOW GTEx Tissue Sample Gene Expression Profiles 1.0 1.11556 Mitochondrial pyruvate dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.199 WM2664 CCLE Cell Line Gene Expression Profiles 1.0 1.68613 CRACR2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02303 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RRP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32243 G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.939749 PNMA6F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66796 mouth TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054782 Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null placenta HPA Tissue Protein Expression Profiles 1.0 1.0705 FXR MotifMap Predicted Transcription Factor Targets 1.0 null SCABER DepMap CRISPR Gene Dependency 1.0 2.64194 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MIR221_KD_GDS4054_455_human_MCF7 breast cancer cells (fulvestrant-resistant) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ZNF550 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28461 EIF3M CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48352 Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55F-0126-SM-48FCK GTEx Tissue Sample Gene Expression Profiles 1.0 1.05763 SKMEL3 CCLE Cell Line Gene Expression Profiles 1.0 1.42844 abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.150721 USF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80094 GSE216043_10_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-RM2N-0926-SM-48FD1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.933883 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37415 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Testicular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.292 TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.2608 inner SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37208 HSFY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17109 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 1.46915 neuroblastoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.30032 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.066 Ankylosing Spondylitides_macrophage_GSE11886 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.39582 TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.9404 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DN-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052672 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null TMEM8B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.42162 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-X4EP-0626-SM-3P621 GTEx Tissue Sample Gene Expression Profiles 1.0 0.83495 496100439_PCx_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.53706 abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.150721 Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-W5X1-0826-SM-3GILN GTEx Tissue Sample Gene Expression Profiles 1.0 0.987983 MAGED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22136 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XGQ4-2626-SM-4AT6B GTEx Tissue Sample Gene Expression Profiles 1.0 1.15807 P300-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984957 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053472 496100334_PCx_probable Alzheimer's disease_no TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.394 ACBD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73878 GTEX-SNOS-1226-SM-4DM5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.914208 GTEX-X3Y1-0426-SM-3P5Z4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.900592 vagina HPA Tissue Protein Expression Profiles -1.0 -1.03402 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.902952 ZNF444 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16484 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 2.76909 GTEX-TMMY-0726-SM-33HBE GTEx Tissue Sample Gene Expression Profiles 1.0 1.198 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049275 UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.874136 Axonemal central apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.206 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26821 ETS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08153 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.84258 MZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.69275 CLPP_KO_GSE40207_378_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Embryonic carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.739 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4701 GTEX-QLQ7-1626-SM-2S1R8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07267 ELOVL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54013 AK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40993 GTEX-WYJK-0526-SM-3NM8Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.15939 GTEX-QLQW-1126-SM-2S1Q8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02281 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78465 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null nucleus GO Cellular Component Annotations 2023 1.0 null Secondary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.852 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12643 GSE224311_3_v_0_chaetocin_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940846 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.8563 cingulate gyrus, parietal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.847676 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.156078 SARS-CoV MA15_Day7-PFU-10^4_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.53075 round GeneRIF Biological Term Annotations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VPS4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39018 CSPG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05001 NFIB-24661679-E16.5 LUNG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BC3C CCLE Cell Line Gene CNV Profiles 1.0 1.52215 H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.79217 SEPTIN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90206 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07738 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC12A9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6073 CEP72 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05569 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26355 Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DIDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77842 primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927101 Sperm cytoplasmic droplet COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.053 SAMD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51969 Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-YA-A8S7-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lack GeneRIF Biological Term Annotations 1.0 null CYB561 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84918 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100659_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.33035 Pelvic varices DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.919 PABPC4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29408 496100401_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.82821 GTEX-QDT8-0626-SM-48TYW GTEx Tissue Sample Gene Expression Profiles 1.0 1.38732 cytoplasm GO Cellular Component Annotations 2015 1.0 null Protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.717 CCAR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66246 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29968 H2BC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.19636 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.825553 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.4692 hippocampus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.85538 HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.885615 GTEX-SSA3-0426-SM-32QPI GTEx Tissue Sample Gene Expression Profiles 1.0 0.85225 PTPRCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33445 Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37816 ZIC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44636 NCIH211 CCLE Cell Line Gene CNV Profiles 1.0 1.36083 KLHDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13088 Septin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.922 DOC2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81097 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.939749 fibrous GeneRIF Biological Term Annotations 1.0 null ADSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29625 Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JRK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72508 HSPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48875 Flagellate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.071 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.21 Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.227 GTEX-S4UY-0726-SM-4AD6X GTEx Tissue Sample Gene Expression Profiles 1.0 0.834029 HUG1N CCLE Cell Line Gene CNV Profiles 1.0 1.99146 Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LCLC-97TM1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17189 TIGAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94669 GTEX-QDVN-2026-SM-3GAEP GTEx Tissue Sample Gene Expression Profiles 1.0 1.07011 NDUFB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63739 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-O5YW-1426-SM-3MJHF GTEx Tissue Sample Gene Expression Profiles 1.0 1.00815 GSDMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02334 ACCMESO1 DepMap CRISPR Gene Dependency 1.0 2.24797 ChIP_RNF2_22325148 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null FHIP2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29821 EZH2 ENCODE Transcription Factor Targets 1.0 null NCI-H1437 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22941 CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051457 uterine endometrium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.144903 CLPP_KO_GSE40207_388_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CEP131 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20703 GNG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02421 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cSARS Bat SRBD_54Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.24381 GSE164494_1_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures -1.0 null FBXO42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52156 NXPE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30472 cell part GO Cellular Component Annotations 2015 1.0 null SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.865361 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039566 GTEX-QEG4-0226-SM-2S1PY GTEx Tissue Sample Gene Expression Profiles 1.0 1.13742 frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.22924 CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 18768393-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null PMC9314667-Table_1.xlsx-Regulons-MITF_MITF Rummagene Transcription Factor Associations 2026 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.55182 Necrosis CTD Gene-Disease Associations 1.0 1.20295 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.969959 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22125 GSE102870_11_v_0_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null OCUB-M COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25477 CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RSPRY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65604 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.37482 Septum pellucidum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.733 GTEX-R55F-1726-SM-2TF4R GTEx Tissue Sample Gene Expression Profiles 1.0 0.999045 SOX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2616 GCDH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9648 CDCA7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61215 ZBTB7C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89965 SS18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.26742 level GeneRIF Biological Term Annotations 1.0 null NANOG-16518401-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-X62O-0126-SM-4E3JN GTEx Tissue Sample Gene Expression Profiles 1.0 1.22343 TRAFD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57853 KDM5A ENCODE Transcription Factor Targets 1.0 null predominantly GeneRIF Biological Term Annotations 1.0 null Zona pellucida TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.888 B3GALNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25098 Synaptonemal structure COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.789 ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.02327 SIPA1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73039 ZSCAN18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1641 STX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20375 GATA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.082 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.862807 JHH6 CCLE Cell Line Gene CNV Profiles -1.0 -1.46591 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.58338 riilike GeneRIF Biological Term Annotations 1.0 null A-CA-04-2009(H1N1)_48Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.00174 ischemic GeneRIF Biological Term Annotations 1.0 null mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26355 E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051847 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.930512 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051187 Intraciliary transport particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.1 SW1783 CCLE Cell Line Gene CNV Profiles -1.0 -1.75405 mRNA_POU5F1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-XQ3S-1426-SM-4BOPR GTEx Tissue Sample Gene Expression Profiles 1.0 0.936827 GTEX-WFON-1926-SM-3LK7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.24198 Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.1693 TRIM22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82309 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043699 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.59792 rostral (anterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.949102 Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKMEL24 CCLE Cell Line Gene Expression Profiles 1.0 1.43573 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82C-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UACC257 CCLE Cell Line Gene Expression Profiles 1.0 1.91881 posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07229 YY1 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RELA_01_80 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.83482 GTEX-UPIC-1626-SM-4IHKT GTEx Tissue Sample Gene Expression Profiles 1.0 0.963029 CLOCK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1025 CBLL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55711 YAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40189 TC71 DepMap CRISPR Gene Dependency 1.0 2.23336 RFX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7108 U87MG DepMap CRISPR Gene Dependency 1.0 2.58689 FOXS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35934 OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043052 BBS10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63317 Semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.409 MDAPCA2B CCLE Cell Line Gene CNV Profiles -1.0 -1.99777 CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LTC4S CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11108 leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065189 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 ZMYM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70065 Seminal vesicle fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.819 ZNF473 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64148 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14004 NCIH596 CCLE Cell Line Gene Expression Profiles -1.0 -1.74404 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACTR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74825 osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.928566 NCIH2196 CCLE Cell Line Gene CNV Profiles 1.0 1.61152 HCC70 CCLE Cell Line Gene CNV Profiles 1.0 1.63505 PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33005 HCC95 CCLE Cell Line Gene CNV Profiles -1.0 -1.41117 PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null GSE169205_3_v_6_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 RXRA ENCODE Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.756 GSE216043_10_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WH7G-2326-SM-3NMBC GTEx Tissue Sample Gene Expression Profiles 1.0 0.836608 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.095529 RS4-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU2F2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88771 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CORL23 CCLE Cell Line Gene CNV Profiles 1.0 1.32882 SQ1 CCLE Cell Line Gene CNV Profiles 1.0 1.6585 RFX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.5304 FTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49873 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 0.82414 PMC6366065-13075_2019_1816_MOESM1_ESM.xlsx-DOD_Skin_imputed_log2_median_ce-Name_PIN1 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spermatids GeneRIF Biological Term Annotations 1.0 null GTEX-T5JC-2126-SM-32PMO GTEx Tissue Sample Gene Expression Profiles 1.0 1.01061 HCC2157 CCLE Cell Line Gene Expression Profiles 1.0 1.53809 MRTFB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94999 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.87492 SKMEL2 CCLE Cell Line Gene Expression Profiles 1.0 1.46701 nucleus GO Cellular Component Annotations 2025 1.0 null Axonemal dynein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.616 CEP76 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53425 PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00928 Tonne-Kalscheuer syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.266 MTA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73974 ATP2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5378 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.365 mRNA_MYBL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-R55E-0126-SM-2TC5Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.08036 SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY ChEA Transcription Factor Targets 2022 1.0 null PMC9314667-Table_1.xlsx-Regulons-SOX10_SOX10 Rummagene Transcription Factor Associations 2026 1.0 null Outer acrosomal membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.146 CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.487 GSU CCLE Cell Line Gene CNV Profiles 1.0 1.87104 GTEX-V955-2026-SM-3GAFA GTEx Tissue Sample Gene Expression Profiles 1.0 0.856677 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SARS-BatSRBD_0Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.56082 H3C4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23516 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.901671 496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03459 Cytoplasmic region COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.887 allelic GeneRIF Biological Term Annotations 1.0 null primary motor cortex (area M1, area 4)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.841865 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE175787_5_v_10_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ZNF76 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7531 Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 37.0942 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.912807 stratum basale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.421529 CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FGFR3_knockdown_173_GSE41035 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.5445 adenoid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.318407 RH41 CCLE Cell Line Gene CNV Profiles -1.0 -1.56002 Supporting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.393 snp GeneRIF Biological Term Annotations 1.0 null MOGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30721 NCIH1648 CCLE Cell Line Gene CNV Profiles 1.0 1.44367 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.2667 heart muscle HPA Tissue Gene Expression Profiles 1.0 0.853755 PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null MKN28 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF322 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42377 primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.20252 akap3 GeneRIF Biological Term Annotations 1.0 null POLR2I CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45068 ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068159 SMAD2/3-21741376-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.74 regulation of protein phosphorylation GO Biological Process Annotations 2023 1.0 null GTEX-Q734-1926-SM-2I5EV GTEx Tissue Sample Gene Expression Profiles 1.0 0.839011 ZNF589 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51569 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spermatogenic failure 9 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.654 dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.919664 GSE214931_1_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null PMC9174176-41467_2022_30924_MOESM5_ESM.xlsx-OC2-SYMBOL_ONECUT2 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PM-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANKRD13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59421 RPMI7951 DepMap CRISPR Gene Dependency 1.0 2.10478 BOLA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19253 NMI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90426 GTEX-OHPM-0126-SM-2YUN9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19407 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F3-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053066 SG in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02042 GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Congenital Abnormalities CTD Gene-Disease Associations 1.0 1.13655 Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MED29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14503 SKMEL5 CCLE Cell Line Gene Expression Profiles 1.0 1.75485 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF790 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54608 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.7761 disease GWASdb SNP-Disease Associations 1.0 0.031018 RHO GTPases Activate Rhotekin and Rhophilins Reactome Pathways 2024 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.63344 PAWR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13426 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cortical layer of collagen and cuticulin-based cuticle extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.034 SNU-423 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 SETBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15779 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.66735 urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SEC22C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14506 retina BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.21197 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19766 NFATC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99758 risk GeneRIF Biological Term Annotations 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.38326 AMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34579 MEL-745A cl. DS19 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.83 RRBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98689 abnormal fertility/fecundity MPO Gene-Phenotype Associations 1.0 null CREM ChEA Transcription Factor Targets 1.0 null GSE198165,GSE198166_0_v_2_zfp266_mouse RummaGEO Gene Perturbation Signatures -1.0 null UOK101 DepMap CRISPR Gene Dependency 1.0 4.1384 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65J-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD1 JASPAR Predicted Transcription Factor Targets 1.0 null class GeneRIF Biological Term Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical mucus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.848 MAJIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71959 GSE213228_2_v_0_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30588 Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MORC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65572 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055441 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRARP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5292 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97628 Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QV44-1926-SM-2S1RF GTEx Tissue Sample Gene Expression Profiles 1.0 1.08974 female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 OTT1_KO_GDS4315_146_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null lateral posterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.84478 UBB_KO_GDS3906_494_mouse_Testis - 21 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Vitelline envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.561 MSN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17213 Male pronucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.583 Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C3orf38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80225 Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RERF-GC-1B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.03005 NFIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 47.5285 GTEX-XUJ4-1926-SM-4BOOV GTEx Tissue Sample Gene Expression Profiles 1.0 1.11388 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984957 supramarginal gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.882178 MYC ENCODE Transcription Factor Targets 1.0 null GTEX-PWN1-1426-SM-48TDF GTEx Tissue Sample Gene Expression Profiles 1.0 0.87846 GTEX-XYKS-0226-SM-4BRW3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11357 LAMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77164 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.620071 MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.6377 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RU72-0326-SM-2TF5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.02575 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-0126-SM-2XCFA GTEx Tissue Sample Gene Expression Profiles 1.0 0.852422 496100410_TCx_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18877 lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.224684 salivary gland GTEx Tissue Gene Expression Profiles 1.0 1.01186 Lung squamous cell carcinoma_LUSC_TCGA-66-2757-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARNT_01_315 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60141 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFE280 CCLE Cell Line Gene CNV Profiles 1.0 1.3972 GTEX-UJHI-1426-SM-3DB9C GTEx Tissue Sample Gene Expression Profiles 1.0 1.26621 Sperm fibrous sheath COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.699 ACOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07038 PMC7338542-41389_2020_247_MOESM6_ESM.xlsx-BRN2_2_of_3_DOWN_48_h-Symbol_POU3F2 Rummagene Transcription Factor Associations 2026 1.0 null igg GeneRIF Biological Term Annotations 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WRHU-2826-SM-3MJG8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.968124 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.31101 MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5091 FASN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17242 ZNF782 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18185 NCIH684 CCLE Cell Line Gene Expression Profiles -1.0 -1.63335 intracellular organelle GO Cellular Component Annotations 2015 1.0 null Vein disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.52 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15647 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.12818 496100377_PCx_no dementia_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.84155 BEND5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51535 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.60572 TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of protein modification process GO Biological Process Annotations 2025 1.0 null Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40446 reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04225 Vas deferens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.279 PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null FOXP1-21924763-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null abnormal reproductive system physiology MPO Gene-Phenotype Associations 1.0 null Sperm midpiece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.802 EPHA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1445 NDUFA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91832 Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN-21703547-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.241 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cAMP-dependent protein kinase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.586 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.917368 HS695T CCLE Cell Line Gene Expression Profiles 1.0 1.50046 breast carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.164571 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00928 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4891-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null men GeneRIF Biological Term Annotations 1.0 null MAD2L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.4586 dorsolateral prefrontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04752 NFIB ChEA Transcription Factor Targets 1.0 null GTEX-UPK5-2326-SM-3P5Z8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879126 CAL51 DepMap CRISPR Gene Dependency 1.0 4.53794 VP229 DepMap CRISPR Gene Dependency 1.0 4.62261 MXI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.24138 LDB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27646 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KNOP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6446 SPI1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cabyr GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5489-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null M059J Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.83298 Varicocele DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.051 FOXH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9401 TP63 ChEA Transcription Factor Targets 1.0 null PMAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90098 somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.347038 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.847652 EGI-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null KLF1 ChEA Transcription Factor Targets 1.0 null NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.6715 sheath GeneRIF Biological Term Annotations 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null GTEX-VUSG-2226-SM-4KKZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.31193 496100323_FWM_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.2949 orbital frontal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.909024 SKMEL28 CCLE Cell Line Gene Expression Profiles 1.0 3.31528 Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GP5D DepMap CRISPR Gene Dependency 1.0 6.03634 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52272 Primary oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.836 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.82087 prion disease GWASdb SNP-Disease Associations 1.0 0.608756 Testicular somatic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.03 Annuli extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.034 GTEX-RM2N-1426-SM-2TF4H GTEx Tissue Sample Gene Expression Profiles 1.0 0.916925 GATA3-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KMS-12-BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.83386 FAM111B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8345 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3481 16643655-1300GenesList GeneSigDB Published Gene Signatures 1.0 null GTEX-OHPM-1426-SM-3TW8Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.861357 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940846 GSE216043_10_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null leukocyte GeneRIF Biological Term Annotations 1.0 null Glycoprotein network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.997 SIN3B-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05431 salivary gland HPA Tissue Gene Expression Profiles 1.0 2.21867 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26355 PMC3721393-bjc2013326x2.xls-Melanoma_SOX10_Gene_Signature-Gene_name_SOX10 Rummagene Transcription Factor Associations 2026 1.0 null CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.11727 NB4 DepMap CRISPR Gene Dependency 1.0 2.71437 SOX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33137 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.20437 SNU466 CCLE Cell Line Gene Expression Profiles 1.0 1.39953 GTEX-XOT4-0726-SM-4GIAW GTEx Tissue Sample Gene Expression Profiles 1.0 1.40127 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.3152 A549 DepMap CRISPR Gene Dependency 1.0 2.94632 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.989298 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050673 TCF3/E2A-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null salivarygland_6b HPA Tissue Sample Gene Expression Profiles 1.0 0.949338 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4701-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE209938_0_v_1_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04379 GSE232218_1_v_0_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null follicle-stimulating hormone complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.606 MBD3L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05735 GTEX-XPVG-1826-SM-4B64X GTEx Tissue Sample Gene Expression Profiles 1.0 0.874812 SNF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08996 EPCAM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40051 endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.49931 ROR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53265 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.66054 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17338 AIM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97073 ZSCAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72208 Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Seminiferous tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.648 HCC1500 CCLE Cell Line Gene CNV Profiles -1.0 -1.59931 genotypic GeneRIF Biological Term Annotations 1.0 null GTEX-WY7C-2126-SM-3NB2R GTEx Tissue Sample Gene Expression Profiles 1.0 1.0324 RAMOS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.24517 MINO CCLE Cell Line Gene CNV Profiles -1.0 -1.64697 cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.072873 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3721393-bjc2013326x2.xls-Breast_Cancer_SOX10_Gene_Sig-Unnamed_1_SOX10 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COLO741 CCLE Cell Line Gene Expression Profiles 1.0 1.76528 chronic obstructive pulmonary disease GWASdb SNP-Disease Associations 1.0 0.72376 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22761 ACAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74478 H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane bounded cell projection organization GO Biological Process Annotations 2025 1.0 null Sperm connecting piece COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.973 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47821 basal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.483986 Vgamma9Vdelta2 T-lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.024 ZNF574 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.8537 striatum_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.899106 PRKCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49644 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 2.048 GTEX-QEG5-0226-SM-2I5GI GTEx Tissue Sample Gene Expression Profiles 1.0 0.867326 primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.47012 MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-1926-SM-47JYP GTEx Tissue Sample Gene Expression Profiles 1.0 0.915603 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.721 AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07741 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Signal Transduction Reactome Pathways 2024 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.84739 CCNA1 MSigDB Cancer Gene Co-expression Modules 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-5395-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.217 DEDD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66932 Testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.122 RTF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21441 EBF1 ENCODE Transcription Factor Targets 1.0 null STAT6_01_85 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 0.76006 testis GeneRIF Biological Term Annotations 1.0 null TBX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68199 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE118077_1_v_8_sprr5_human RummaGEO Gene Perturbation Signatures 1.0 null lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28431 H3K27me3_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ANKFY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74456 LN319 DepMap CRISPR Gene Dependency 1.0 2.44099 SNU398 CCLE Cell Line Gene Expression Profiles -1.0 -1.87023 TTYH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64705 Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null salivarygland BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32305 scaffolding GeneRIF Biological Term Annotations 1.0 null GSE182921_0_v_1_slit2_human RummaGEO Gene Perturbation Signatures 1.0 null BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.338884 protein localization to cilium GO Biological Process Annotations 2025 1.0 null located GeneRIF Biological Term Annotations 1.0 null rara_21299862_mcf7_lof_human__gds4065 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.17315 HCC2218 CCLE Cell Line Gene CNV Profiles -1.0 -2.25885 GTEX-U412-0426-SM-3DB9O GTEx Tissue Sample Gene Expression Profiles 1.0 0.858928 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SK-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHCHD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77288 DANG CCLE Cell Line Gene CNV Profiles 1.0 1.43382 GTEX-SSA3-0526-SM-32QPL GTEx Tissue Sample Gene Expression Profiles 1.0 1.29224 mRNA_WHSC2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null abnormal sperm physiology MPO Gene-Phenotype Associations 1.0 null Testicular vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.605 P53-21459846-SAOS-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.663 Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 Dimerization-anchoring domain of cAMP-dependent protein kinase, regulatory subunit InterPro Predicted Protein Domain Annotations 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 icSARS CoV_54Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.32603 TBKBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15091 GSE229344_1_v_0_cyb5r3_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XXEK-2226-SM-4BRUM GTEx Tissue Sample Gene Expression Profiles 1.0 0.858305 GTEX-OXRL-0126-SM-2YUMP GTEx Tissue Sample Gene Expression Profiles 1.0 1.12996 ARID4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81512 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null RIMOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30658 ACAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06862 496100358_HIP_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.37551 Testicular cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.183 ARL10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90202 CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21211 abnormal sperm motility MPO Gene-Phenotype Associations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DD-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HAUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7184 AKAP3 Pathway Commons Protein-Protein Interactions 1.0 null duodenum HPA Tissue Gene Expression Profiles -1.0 -0.861535 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.789796 IFITM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39771 lymph node HPA Tissue Gene Expression Profiles -1.0 -0.861535 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.57988 YWHAB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78938 dorsolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.929747 ZNF514 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.969 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null PIK3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67045 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.886881 primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18056 end GeneRIF Biological Term Annotations 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Zygotene cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.697 PCBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00989 Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.01605 anterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.956741 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 PSMG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1112 colonrectum_c HPA Tissue Sample Gene Expression Profiles 1.0 0.82838 NP8 DepMap CRISPR Gene Dependency 1.0 2.28946 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.092562 MDA-MB-436 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64237 GSE258991_5_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Ischemia HuGE Navigator Gene-Phenotype Associations 1.0 null CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null region GeneRIF Biological Term Annotations 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06309 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CLPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39461 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GDF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28767 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DOLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31791 FARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87493 anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.974931 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19766 YAP1-20516196-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.247399 Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein localization to organelle GO Biological Process Annotations 2023 1.0 null Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.317 ZNF780B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69953 Spermatic cord torsion DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.104 SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9159 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null form GeneRIF Biological Term Annotations 1.0 null HUH6 DepMap CRISPR Gene Dependency 1.0 4.38212 TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null KCNIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27456 Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.98179 TDRD3-21172665-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ALDH16A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82215 Malignant conjunctival melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.321 GTEX-SUCS-1926-SM-32PM3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.928832 HSFY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84704 primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63221 ZNF318 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63888 molecular_function GO Molecular Function Annotations 2015 1.0 null SARS-CoV MA15_Day1-PFU-10^3_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.59416 JVE127 DepMap CRISPR Gene Dependency 1.0 2.48194 COV504 CCLE Cell Line Gene CNV Profiles 1.0 1.99227 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF24_01_353 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.0058 Six4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1608 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958996 GSE213228_4_v_0_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null organelle organization GO Biological Process Annotations 2025 1.0 null Sertoli cell-only syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.001 Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.405 GTEX-RNOR-0126-SM-2TF57 GTEx Tissue Sample Gene Expression Profiles 1.0 0.925625 ZNF521 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81436 GTEX-SSA3-0126-SM-32QPU GTEx Tissue Sample Gene Expression Profiles 1.0 1.15554 Microfilarial stage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.939 Lung adenocarcinoma_LUAD_TCGA-05-4396-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 ZNF154 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65156 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.3399 PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR Rummagene Transcription Factor Associations 2026 1.0 null Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20548 gh1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.76 Epididymal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.361 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.859629 oral cavity cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.118194 HT-144 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65795 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null icSARS CoV_48Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.39834 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spine apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.826 sk-n-sh cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.1936 NCIH226 CCLE Cell Line Gene CNV Profiles -1.0 -1.96228 ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5404 WM115 CCLE Cell Line Gene Expression Profiles 1.0 1.41514 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 PDF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.46588 NFIB-24661679-LUNG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82319 C32 CCLE Cell Line Gene Expression Profiles 1.0 2.53276 dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.852314 PMC9314667-Table_1.xlsx-Regulons-ELF1_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-V1D1-2026-SM-3GAF4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07406 Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ciliopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.134 CTCF ENCODE Transcription Factor Targets 1.0 null than GeneRIF Biological Term Annotations 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.901671 variants GeneRIF Biological Term Annotations 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.92802 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0334 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08908 MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.665393 Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SALL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82052 PA1 DepMap CRISPR Gene Dependency 1.0 2.35777 JUN-21703547-K562-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.51301 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.83137 Ciliary tip COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.744 ASXL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37188 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.752 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.642 GTEX-XUW1-2326-SM-4BOO5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15668 FOS JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4216 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.80553 MTRFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53975 EIF4E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47933 RAB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21832 Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFATC2IP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62147 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55404 ZNF555 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56455 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YAMATO DepMap CRISPR Gene Dependency 1.0 4.59594 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null KIF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.64892 testis TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 motile cilium GO Cellular Component Annotations 2025 1.0 null motility GeneRIF Biological Term Annotations 1.0 null GTEX-WFG8-2126-SM-3GIKQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.22485 mRNA_SMAD4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF135 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71105 GTEX-P4PP-1426-SM-3NM9L GTEx Tissue Sample Gene Expression Profiles 1.0 1.22153 Axonemal central pair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.22 autologous GeneRIF Biological Term Annotations 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GET4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27982 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52256 SNU16 DepMap CRISPR Gene Dependency 1.0 2.03332 PCSK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98768 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.917368 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.98275 NCIH660 CCLE Cell Line Gene Expression Profiles -1.0 -1.98632 MLF1 MSigDB Cancer Gene Co-expression Modules 1.0 null 496100405_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.41526 MEX3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74251 rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06256 CACNG7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01472 PICK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77277 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.26959 ZNF705D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79553 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Pancreatic adenocarcinoma_PAAD_TCGA-L1-A7W4-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216274,GSE216292_4_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.965745 Peritubular contractile cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.988 ventral lateral nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50601 Intraciliary transport particle B COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.225 BL41 CCLE Cell Line Gene CNV Profiles -1.0 -2.2568 GTEX-QDVJ-1726-SM-2I5FX GTEx Tissue Sample Gene Expression Profiles 1.0 1.07346 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.04874 NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null into GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.2119 Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6982 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.52057 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.48483 CGGBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66713 abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.088249 intracellular membrane-bounded organelle GO Cellular Component Annotations 2025 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOT4-0626-SM-4B66L GTEx Tissue Sample Gene Expression Profiles 1.0 1.26436 TGIF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 72.1387 ZNF562 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44809 Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE191105_0_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF625 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38015 MUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63333 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.58781 GSE140576_0_v_2_plag1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ATMIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79261 SLC39A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34239 CRABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06047 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null CHP212 CCLE Cell Line Gene Expression Profiles -1.0 -1.56228 AKT1_knockdown_43_GSE12291 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.84479 PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B Rummagene Transcription Factor Associations 2026 1.0 null GTEX-TKQ1-1326-SM-4DXU7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.42448 mRNA_ATF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null SPTY2D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78526 MAP3K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22324 inferior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.824786 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.84533 PMC12202500-43018_2025_963_MOESM14_ESM.xlsx-ED_Fig_3i_ref_markergenesetl-Tirosh_MITF_MITF Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.72984 Bulbourethral gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.522 PHF8-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null HT1080 DepMap CRISPR Gene Dependency 1.0 4.55351 ECHDC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1269 GAPVD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42448 GTEX-P4QS-1726-SM-3NB1V GTEx Tissue Sample Gene Expression Profiles 1.0 1.18146 TARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06046 NCI-H460 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940846 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.448 Perturb_354_OE_MITF_SRP298756 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null 496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.94412 ZNF143 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53936 neuroblastoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.082917 HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.01056 NCI-H2196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47357 supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.5823 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19657 GTEX-P4QT-1426-SM-3NMCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.945494 Dynein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.577 FOXP1-21924763-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OPLAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65888 ciliary GeneRIF Biological Term Annotations 1.0 null GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.86742 NANOG ChEA Transcription Factor Targets 1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.77781 Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XXEK-1626-SM-4BRUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.00829 Spermatogenic failure DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.88 Perinuclear theca COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.29 TC-YIK COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TML8-1226-SM-32QON GTEx Tissue Sample Gene Expression Profiles 1.0 1.10526 intracellular part GO Cellular Component Annotations 2015 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68289 GTEX-U3ZN-1926-SM-4DXSG GTEx Tissue Sample Gene Expression Profiles 1.0 1.23804 CHMP4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22219 SNU-387 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.05404 sc11 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.192 NR1H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49554 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61541 metabolic GAD High Level Gene-Disease Associations 1.0 0.305726 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACTR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02221 asthenozoospermic GeneRIF Biological Term Annotations 1.0 null HCC15 CCLE Cell Line Gene CNV Profiles -1.0 -1.45956 CSNK1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52118 GSE198380_0_v_1_phgdh_human RummaGEO Gene Perturbation Signatures -1.0 null myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.106581 RHOT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97539 primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.857922 blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.329361 ZFP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14469 HSC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null nutrition disease GWASdb SNP-Disease Associations 1.0 0.37017 XBP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9206 RUNX2 ChEA Transcription Factor Targets 1.0 null REST-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WK11-2726-SM-3NMAQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.16561 hsa-miR-3115 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GTEX-WQUQ-0426-SM-3MJFU GTEx Tissue Sample Gene Expression Profiles 1.0 0.974779 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF Rummagene Transcription Factor Associations 2026 1.0 null PAXIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18825 paracentral lobule, anterior part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12465 Cilium COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.928626 GTEX-WY7C-2326-SM-3NB2U GTEx Tissue Sample Gene Expression Profiles 1.0 1.0466 leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.203275 PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_GSEA_state_markers-AP1_JUN Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T5JW-2026-SM-4DM63 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32904 GSE213588_10_v_2_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TM31 DepMap CRISPR Gene Dependency 1.0 2.521 Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.318 GTEX-WYVS-1726-SM-3NMAY GTEx Tissue Sample Gene Expression Profiles 1.0 1.40564 pRb_Deficiency_GDS3176_605_mouse_Skin GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.65795 mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.878817 Gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.078 METTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96023 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GSE95386_0_v_1_trim24_human RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMKMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75574 SGF29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3686 GTEX-NFK9-0226-SM-2HMKQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.886685 GSE221386_2_v_0_romidepsin_human RummaGEO Drug Perturbation Signatures -1.0 null IZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1144 GIPC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.29381 SNU-484 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17189 C11orf86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45681 Infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.786 reduced fertility MPO Gene-Phenotype Associations 1.0 null subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.925681 cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.6638 Plasma membrane bounded cell projection cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.208 MDA-PCa-2b cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04072 GTEX-WEY5-2326-SM-3GIKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.05693 CPHXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63257 TMEM186 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29394 LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.232 RCOR3-21632747-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940846 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null TUHR14TKB CCLE Cell Line Gene Expression Profiles -1.0 -1.60696 TTC549 DepMap CRISPR Gene Dependency 1.0 4.79552 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RVH421 CCLE Cell Line Gene Expression Profiles 1.0 2.48692 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 9+0 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.74 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.06 Benign childhood epilepsy with centro-temporal spikes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 EBF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71149 GSE213588_10_v_4_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null HEATR5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19151 GSE218580_1_v_2_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null YAP1 ChEA Transcription Factor Targets 1.0 null CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null decreased litter size MPO Gene-Phenotype Associations 1.0 null JAM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02177 GTEX-XPVG-2126-SM-4B667 GTEx Tissue Sample Gene Expression Profiles 1.0 0.938011 NCIH146 CCLE Cell Line Gene CNV Profiles 1.0 1.52982 GSE213588_10_v_0_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null KMS12BM CCLE Cell Line Gene CNV Profiles -1.0 -1.82648 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050673 CHRD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84434 NKIRAS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79763 GTEX-VJYA-1126-SM-3GIJU GTEx Tissue Sample Gene Expression Profiles 1.0 0.954029 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null irestricted GeneRIF Biological Term Annotations 1.0 null FASTKD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64273 HCC1143 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.23581 GTEX-UPJH-0326-SM-3GADU GTEx Tissue Sample Gene Expression Profiles 1.0 0.836403 GTEX-WXYG-2226-SM-4E3IM GTEx Tissue Sample Gene Expression Profiles 1.0 1.35041 KYM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.53176 Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAKI-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 MDAMB436 CCLE Cell Line Gene CNV Profiles -1.0 -1.42342 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17338 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.005 PTMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26185 TTC709 DepMap CRISPR Gene Dependency 1.0 3.60947 NCIH1734 CCLE Cell Line Gene CNV Profiles -1.0 -2.66887 HCC1569 CCLE Cell Line Gene Expression Profiles 1.0 2.15132 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.45991 Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100555_TCx_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00326 regulation of protein modification process GO Biological Process Annotations 2023 1.0 null 647V DepMap CRISPR Gene Dependency 1.0 3.23721 organelle LOCATE Predicted Protein Localization Annotations 1.0 null mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10928 ZNF606 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19304 MKI67 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72482 LRRC32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52963 GTEX-QVJO-1626-SM-2S1QW GTEx Tissue Sample Gene Expression Profiles 1.0 0.850615 CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null obstructive lung disease GWASdb SNP-Disease Associations 1.0 0.378472 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05701 MALME3M CCLE Cell Line Gene Expression Profiles 1.0 1.90141 TCF4 ChEA Transcription Factor Targets 1.0 null TCF7-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PA-TU-8902 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82697 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05784 VAC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53464 HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.37556 GTEX-XOT4-1126-SM-4B66E GTEx Tissue Sample Gene Expression Profiles 1.0 0.926841 PMC9314667-Table_1.xlsx-Regulons-ETV4_ETV4 Rummagene Transcription Factor Associations 2026 1.0 null KCNE5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28613 myeloid leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.478923 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046782 KMS20 DepMap CRISPR Gene Dependency 1.0 3.44139 GSTK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57886 TEX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40798 VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06378 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.3154 GSE252857_1_v_0_klf15_mouse RummaGEO Gene Perturbation Signatures 1.0 null CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.9621 TEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40646 Alkyl hydroperoxide reductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.944 DB CCLE Cell Line Gene CNV Profiles -1.0 -1.56515 NCI-H2347 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.886428 anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.13425 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984957 CAOV3 CCLE Cell Line Gene CNV Profiles 1.0 1.71087 Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOP-92 COSMIC Cell Line Gene Mutation Profiles 1.0 null IGR37 CCLE Cell Line Gene Expression Profiles 1.0 1.36218 Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TLX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4253 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.66639 SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21916 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null LPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36642 NUDT17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6917 showed GeneRIF Biological Term Annotations 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 7 days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-WRHU-0326-SM-3MJFY GTEx Tissue Sample Gene Expression Profiles 1.0 1.0112 ovary HPA Tissue Gene Expression Profiles -1.0 -0.861535 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -2.06373 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null ONCODG1 CCLE Cell Line Gene CNV Profiles 1.0 2.70817 FOSL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TML8-1326-SM-4DXTO GTEx Tissue Sample Gene Expression Profiles 1.0 0.993211 antibodies GeneRIF Biological Term Annotations 1.0 null Junctional membrane complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.943 NFIC::TLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9375 Seminal plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.479 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.86524 axoneme part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.609086 RGL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10075 Situs inversus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.037 BCL6-25482012-CML-JURL-MK1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null KMH2 CCLE Cell Line Gene CNV Profiles -1.0 -2.83979 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.76379 SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0562 HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.68223 cell property TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.075823 NCIH196 CCLE Cell Line Gene CNV Profiles 1.0 1.74735 GTEX-XYKS-2126-SM-4E3IB GTEx Tissue Sample Gene Expression Profiles 1.0 0.906169 HSF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27201 PJA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30598 male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.466928 salivarygland_6c HPA Tissue Sample Gene Expression Profiles 1.0 0.885906 KYSE-180 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 Etoposide CTD Gene-Chemical Interactions 1.0 null HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Teratozoospermia DisGeNET Gene-Disease Associations 1.0 null Primary spermatocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.129 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.688 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18501 mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073099 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XYKS-1426-SM-4BRUO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09297 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.82848 anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4298 BT-474 COSMIC Cell Line Gene Mutation Profiles 1.0 null SHMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15462 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06475 GTEX-WYBS-0926-SM-3NM94 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41894 ECGI10 DepMap CRISPR Gene Dependency 1.0 2.01592 SLC25A22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72227 HEY1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2852 cuneus, left, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14272 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.168 ZFP57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90916 LY6E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92796 salivarygland_6a HPA Tissue Sample Gene Expression Profiles 1.0 1.02947 Acrosomal vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.273 acute myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.181222 NCIH1693 CCLE Cell Line Gene Expression Profiles -1.0 -1.86506 DNAJB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62685 Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBED-2226-SM-47JYQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.855016 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostomium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.773 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33107 PAIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69747 protein localization to organelle GO Biological Process Annotations 2025 1.0 null Varicose veins DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.732 GTEX-W5X1-2326-SM-3GIL6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23623 GTP-Rho-Rhpn1-Ropn1 complex CORUM Protein Complexes 1.0 null MYF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6323 GFOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21385 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.50135 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Stroke HuGE Navigator Gene-Phenotype Associations 1.0 null ZSWIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57121 GTEX-T5JC-0426-SM-32PLO GTEx Tissue Sample Gene Expression Profiles 1.0 0.906555 Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XUZC-1326-SM-4BRV2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.899842 Conjunctival epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.613 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.91794 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053326 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.055466 GTEX-VJWN-0126-SM-3GIK7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.939948 organelle organization GO Biological Process Annotations 2023 1.0 null GSE102505_4_v_2_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RDH14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32214 ZNF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7403 Implantation fossa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.84 TMEM185A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60615 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.57081 cuneus, right, striate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.64986 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.90167 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80555 GTEX-XBED-1626-SM-47JYN GTEx Tissue Sample Gene Expression Profiles 1.0 0.8246 cell part LOCATE Predicted Protein Localization Annotations 1.0 null CAL62 CCLE Cell Line Gene CNV Profiles 1.0 1.33568 TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -2.25794 H3K27me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SIN3B ChEA Transcription Factor Targets 1.0 null PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_3_AP1_Up_JUN Rummagene Transcription Factor Associations 2026 1.0 null outer CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.73279 CUL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51862 GSE252857_1_v_0_prednisone_mouse RummaGEO Drug Perturbation Signatures 1.0 null CELF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29496 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null ZNF416 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71222 occipito-temporal gyrus, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0914 IFT57 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11949 H2BC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59098 Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cryptorchidism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.585 inner SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.871781 Primary hematopoietic stem cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.70321 19204204-SupplementaryTable5 GeneSigDB Published Gene Signatures 1.0 null myb_16205643_primary_monocytes_gof_human_gpl570_gse2816 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.190747 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.3773 SPA17 Pathway Commons Protein-Protein Interactions 1.0 null CREB3L4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.6172 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.03272 KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-UJHI-1526-SM-3DB99 GTEx Tissue Sample Gene Expression Profiles 1.0 0.842155 GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CHSY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47385 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.047 GSE162892_3_v_1_isox_human RummaGEO Drug Perturbation Signatures -1.0 null GOSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0652 acute myeloid leukemia cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.588431 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB435S CCLE Cell Line Gene CNV Profiles 1.0 1.33755 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1817 GTEX-S341-1526-SM-4AD6K GTEx Tissue Sample Gene Expression Profiles 1.0 1.15975 Leukocyte disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.153 FOSL2 ENCODE Transcription Factor Targets 1.0 null thyroid gland HPA Tissue Protein Expression Profiles 1.0 1.0705 SMIM29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78767 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.032465 GTEX-TKQ1-1026-SM-4GICL GTEx Tissue Sample Gene Expression Profiles 1.0 0.994246 GTEX-T2IS-1526-SM-32QPR GTEx Tissue Sample Gene Expression Profiles 1.0 1.40739 Lung squamous cell carcinoma_LUSC_TCGA-85-7699-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7038 TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46643 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42248 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.849991 H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Accessory sex gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.084 SFMBT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.6442 NCI-H345 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.73265 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57232 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76727 outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33041 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null heart muscle HPA Tissue Protein Expression Profiles 1.0 1.0705 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null FOS_01_99 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.60296 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.457 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.939749 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MB-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BANF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75243 KCNIP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07312 MYC_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null effect GeneRIF Biological Term Annotations 1.0 null CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940846 TPST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56041 testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.36463 F-actin capping protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.733 LN464 CCLE Cell Line Gene Expression Profiles 1.0 2.10329 NIPAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90703 ENSG00000284691 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30719 binding GO Molecular Function Annotations 2015 1.0 null MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22322 SG in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30834 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MR-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FTH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01361 internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42869 ICAM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30406 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 REST-21632747-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null DNAJC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55534 KIFBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42997 GTEX-Q2AG-0126-SM-33HBV GTEx Tissue Sample Gene Expression Profiles 1.0 1.04229 JHOS2 DepMap CRISPR Gene Dependency 1.0 4.22561 dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33508 posterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18172 had GeneRIF Biological Term Annotations 1.0 null GTEX-WFON-1426-SM-4LVMT GTEx Tissue Sample Gene Expression Profiles 1.0 1.11242 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-CA-04-2009(H1N1)_36Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.58632 CREM-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.057 HLA-E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57875 SIRT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1998 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23904 GTEX-VJWN-0726-SM-3GIJ8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22802 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.55415 PGR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65799 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.187 JUN ChEA Transcription Factor Targets 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.7933 NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.939749 Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PCYOX1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83569 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null USF1 ENCODE Transcription Factor Targets 1.0 null Katanin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.632 GFI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07313 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4483 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.103 Conjunctival cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.225 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.84333 CPNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.786 stomach HPA Tissue Protein Expression Profiles 1.0 1.0705 Bone marrow cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.259 orbital frontal cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.962888 testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.56643 Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2172 COSMIC Cell Line Gene Mutation Profiles 1.0 null Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YJ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stolon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.883 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.891808 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.840373 BARX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39229 Perturb_15979_KO_Tsga8_SRP254760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.7798 presence GeneRIF Biological Term Annotations 1.0 null MGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30094 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26355 GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 0.930712 USP45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59588 lower GeneRIF Biological Term Annotations 1.0 null breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048848 cellular_component GO Cellular Component Annotations 2015 1.0 null ZNF774 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71403 blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 P68-20966046-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NI-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lung disease GWASdb SNP-Disease Associations 1.0 0.224684 ZBED2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3971 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041348 GSE188870,GSE188871_1_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null Radial spoke COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.898 GTEX-XUZC-1626-SM-4BRVP GTEx Tissue Sample Gene Expression Profiles 1.0 1.46532 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.970161 PIP4K2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.555 GSE175787_5_v_0_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-POMQ-0326-SM-2I5FO GTEx Tissue Sample Gene Expression Profiles 1.0 0.866033 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33218 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9925 Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.5843 ZNF680 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46246 MZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.825889 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.0814 PRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89043 posteroventral (inferior) parietal cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.76307 Gonadal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 CD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.946 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.36157 GTEX-VUSG-2526-SM-4KL1V GTEx Tissue Sample Gene Expression Profiles 1.0 0.919374 GSE218580_1_v_0_fentanyl_mouse RummaGEO Drug Perturbation Signatures -1.0 null tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.970412 piece GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5976-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54516 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.21403 DPH5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73922 Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.715 ZFP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72907 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-SE5C-1526-SM-4BRWU GTEx Tissue Sample Gene Expression Profiles 1.0 0.888276 KXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37482 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34057 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null orbital frontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34628 DDB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66356 A-CA-04-2009(H1N1)_48Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.99456 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.41786 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null 11823860-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null GSE206226_2_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07738 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12845 Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE200430_1_v_0_sema3d_human RummaGEO Gene Perturbation Signatures -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.846665 FGFR1_drugactivation_149_GSE32316 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.45938 Visceral heterotaxy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XK95-0226-SM-4AT58 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06995 hippocampus (hippocampal formation)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.872968 Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.748 SRSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41528 CLPP_KO_GDS4791_374_mouse_Testies GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-XYKS-1326-SM-4BRUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.42162 EMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05884 Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TF-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal pole, right, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.837734 ACSBG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79752 Pavement epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.705 TGIF2LY JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0876 496100621_TCx_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.35758 TP53 ChEA Transcription Factor Targets 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-SIU8-0126-SM-2XCDT GTEx Tissue Sample Gene Expression Profiles 1.0 0.984132 lymphocytes GeneRIF Biological Term Annotations 1.0 null H3K27me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null K029AX CCLE Cell Line Gene Expression Profiles 1.0 1.91422 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMG8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3805 RNF7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28894 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058864 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MRM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1509 brain disease GWASdb SNP-Disease Associations 1.0 0.146443 COLO679 DepMap CRISPR Gene Dependency 1.0 2.67349 TP53-20018659-R1E-MOUSE ChEA Transcription Factor Targets 2022 1.0 null dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CCNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95316 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE216043_10_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null FOXK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73934 ZSCAN30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46486 SYDE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02221 Pachytene cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.781 Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF735 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03014 PFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72507 MEGF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71248 recurrent viral infections GWASdb SNP-Phenotype Associations 1.0 0.517014 voltage-gated calcium channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.028 Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07806 KCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58748 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14709 FRAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21366 LIN7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22085 A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.91892 AS3MT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76768 GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null JAK2_activemutant_72_GSE21842 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.64029 spermatozoa GeneRIF Biological Term Annotations 1.0 null temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46996 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14709 cilium GO Cellular Component Annotations 2023 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25U-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spermatogenic failure 53 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.461 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral division of VL Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.51709 GSE102870_1_v_0_nr1h4_human RummaGEO Gene Perturbation Signatures -1.0 null temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.14005 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MO-0326-SM-32QOK GTEx Tissue Sample Gene Expression Profiles 1.0 1.22943 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.901671 Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Motile cilium COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WSB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42476 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 2.12567 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32764 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.05858 ACACB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36165 H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12415 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.615099 UGT3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4249 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19415 GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.98774 Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.11419 ZFYVE9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6671 CENPM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29808 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.27855 GTEX-RN64-0126-SM-2TC68 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29602 RXRA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-V1D1-2226-SM-3NMAX GTEx Tissue Sample Gene Expression Profiles 1.0 1.13665 SLC38A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34169 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.991631 FAM120B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85166 ciliary part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.122088 recurrent infections GWASdb SNP-Phenotype Associations 1.0 0.277743 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20X-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.72438 GSE127916_1_v_4_nras_human RummaGEO Gene Perturbation Signatures -1.0 null GOTO COSMIC Cell Line Gene Mutation Profiles 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVCA433 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.75001 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1428 DepMap CRISPR Gene Dependency 1.0 2.09438 OLFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05065 A2BAR_Deficiency_GDS3662_520_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-SE5C-2126-SM-4BRUJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.24001 Eleocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.045 Seminiferous epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.397 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.986041 precuneus, left, inferior lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.90551 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.98499 thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047838 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.903926 H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null vivo GeneRIF Biological Term Annotations 1.0 null CPNE7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23432 GTEX-X5EB-1726-SM-4E3J7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.834224 superficial layers of olfactory entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31149 RHJT DepMap CRISPR Gene Dependency 1.0 2.47216 Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.321 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 2.13683 MME CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75507 protein localization to cilium GO Biological Process Annotations 2023 1.0 null GTEX-UJMC-1326-SM-4IHLS GTEx Tissue Sample Gene Expression Profiles 1.0 0.846846 Lateral hypodermal chord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.467 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.90859 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.901671 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CLPP_KO_GDS4791_104_mouse_testis GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null myoepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.67495 IVD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30347 GTEX-X638-0126-SM-47JZ8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.967656 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7357 leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058288 outer SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04051 PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10 Rummagene Transcription Factor Associations 2026 1.0 null NNMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27544 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IM-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.79718 indusium griseum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12861 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.04793 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Oligoasthenoteratozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.611 GTEX-RU72-0926-SM-2TF6B GTEx Tissue Sample Gene Expression Profiles 1.0 1.00891 GSE181749_0_v_1_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Septin cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.574 NB1 CCLE Cell Line Gene CNV Profiles -1.0 -1.74344 C2BBE1 DepMap CRISPR Gene Dependency 1.0 2.99537 GTEX-OIZG-0726-SM-33HBL GTEx Tissue Sample Gene Expression Profiles 1.0 0.99712 cd8.Tcell BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.947913 SKNAS DepMap CRISPR Gene Dependency 1.0 2.34853 PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.9411 GTEX-SJXC-0126-SM-2XCFF GTEx Tissue Sample Gene Expression Profiles 1.0 1.07999 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.02138 apoplexy; brain ischemia; stroke GAD Gene-Disease Associations 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.38116 male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.32701 GTEX-SIU7-1626-SM-4BRUK GTEx Tissue Sample Gene Expression Profiles 1.0 1.37706 abnormal litter size MPO Gene-Phenotype Associations 1.0 null CEND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14428 Zbtb2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.474 HS944T CCLE Cell Line Gene Expression Profiles 1.0 1.35103 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.68072 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 INSM1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.375 OUMS23 DepMap CRISPR Gene Dependency 1.0 3.89102 Axonemal microtubule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.285 obesity GWASdb SNP-Disease Associations 1.0 0.665868 SNAI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35967 MARK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19005 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984957 significant GeneRIF Biological Term Annotations 1.0 null TCF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42684 Scrotum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.24 Signaling by Rho GTPases Reactome Pathways 2024 1.0 null GSE169205_3_v_2_sirt5_human RummaGEO Gene Perturbation Signatures -1.0 null DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60608 GTEX-S7SE-0126-SM-2XCD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02813 ZNF843 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1833 UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.52368 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08874 RRAGA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36172 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 2.14277 Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.48009 TGIF2LX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.2776 HOP-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-3647-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.632343 NCI-H28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.844987 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4760-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04701 GSE145323,GSE145324_1_v_0_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-Q2AI-0926-SM-48U1F GTEx Tissue Sample Gene Expression Profiles 1.0 1.06764 able GeneRIF Biological Term Annotations 1.0 null DCAF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02689 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null nervous system disease GWASdb SNP-Disease Associations 1.0 0.049503 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALYREF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30908 primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.12657 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.06236 DOHH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53176 HELZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34404 HARA COSMIC Cell Line Gene Mutation Profiles 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42237 PTEN_01_302 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.61009 TAF1 ENCODE Transcription Factor Targets 1.0 null salivary gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.139256 FOXH1-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null chronic obstructive pulmonary disease GWASdb SNP-Phenotype Associations 1.0 0.623659 MXRA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75597 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.76253 Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-1426-SM-4DXSR GTEx Tissue Sample Gene Expression Profiles 1.0 1.21123 MRPL30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55379 496100641_PCx_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.11321 intermediate portion of DFC (area 9/46) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.4658 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0073 embryoday7.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.829009 WM1799 CCLE Cell Line Gene Expression Profiles 1.0 1.53826 Lung adenocarcinoma_LUAD_TCGA-97-8175-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X3Y1-2026-SM-3P5YM GTEx Tissue Sample Gene Expression Profiles 1.0 0.83372 GAS2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91852 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.266 cardiovascular GAD High Level Gene-Disease Associations 1.0 0.293278 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.638 Inner dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.32 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46261 Mesothelioma_MESO_TCGA-MQ-A4LI-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBAK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67965 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27071 NCIH2081 CCLE Cell Line Gene CNV Profiles 1.0 1.75159 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.05153 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -2.10021 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.72315 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 GTEX-T6MN-0726-SM-32PML GTEx Tissue Sample Gene Expression Profiles 1.0 1.02331 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null primary cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.47442 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59818 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.2184 Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.526 SEPHS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78893 CBR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55192 stroke GeneRIF Biological Term Annotations 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF124 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75582 ZDHHC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47365 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.892 DUSP28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48641 STAT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22646 FGFR3_knockdown_34_GDS4454 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.54452 EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984957 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01108 GTEX-U3ZH-2026-SM-3DB78 GTEx Tissue Sample Gene Expression Profiles 1.0 0.863562 GTEX-OXRK-0226-SM-3NB2G GTEx Tissue Sample Gene Expression Profiles 1.0 0.989048 GTEX-S4P3-1326-SM-4AD6V GTEx Tissue Sample Gene Expression Profiles 1.0 1.28252 Collagen and cuticulin-based cuticle extracellular matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.033 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 LDHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84392 PHYH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72682 mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null GSE208634_1_v_0_doxycycline_human RummaGEO Drug Perturbation Signatures -1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE102505_4_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures -1.0 null NDUFB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57415 lingual gyrus, left, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02527 lateral hypothalamic area, mammillary region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29861