association	dataset	threshold value	standardized value
MEWO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79788
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TI-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848649
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.62734
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00784
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20774
GEM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00558183
BRD-K41604824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17582
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10791
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863308
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45175
BRD-K34106082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03481
VDR-23401126-LCL-AND-THP1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IST-MEL1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K61831307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3353
BRD-K62597218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28326
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K06203116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48298
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20957
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	2.78386
EMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87587
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98209
single-organism transport	GO Biological Process Annotations 2015	1.0	null
QDPR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527203
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926285
BRD-K29441085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02687
BRD-K13089873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13689
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00722521
BRD-K72437469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95251
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05019
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59046
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01964
CRCGN015_MCF10A_48H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.31165
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07034
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07411
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09363
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918755
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9848
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icSARS CoV_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6138
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.898216
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82562
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59114
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30015
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.20183
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22713
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956813
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-A08191729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51983
NDOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70715
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.03859
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HBL-100 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84481
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06081
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
flumetasone-4272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCEAL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51415
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A4U2-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65547
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49395
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18396
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32771
cell projection	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5356
BRCA1_DEPLETION_GDS3791_38_human_Hela	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-4112-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49233
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40155
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02235
BRD-K25868508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98883
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
CP66-MEL	GDSC Cell Line Gene Expression Profiles	1.0	1.58368
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83104
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3466
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33799
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
OR52N4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573139
BRD-K43170571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26103
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64862162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32014
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33104513	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54748
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22419
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89648
BRD-K72501910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17626
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73519
SIGMAR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00515502
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15206
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS746T	CCLE Cell Line Gene CNV Profiles	1.0	1.39548
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.975276
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54994
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53148
NU-1025-313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52152
BRD-K36237864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16435
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04517
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95871937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81683
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994431
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.03859
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
gamete generation	GO Biological Process Annotations 2015	1.0	null
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
chr3_126044692_G_A_b38	GTEx eQTL 2025	1.0	1.8261
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.28845
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
heart_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.830443
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K91548063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01611
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.208
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0355
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27913
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27676
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85669
BRD-K44298652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4805
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51445
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0459
SPI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K39244231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5503
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
TARDBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60271
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MINO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6819
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
FCGR1BP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453104
fat_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
BRD-K30895360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15137
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16061
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1021
C33A	DepMap CRISPR Gene Dependency	1.0	3.24255
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K75710031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38478
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91911
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96832
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85334
Sarcoma_SARC_TCGA-X6-A7WD-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28932578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36206
CRCGN015_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.029
acrosome reaction	GO Biological Process Annotations 2015	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97326
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.273
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Y-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLA-DQB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483058
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5269
ONECUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07625
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32542
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52896
MKI67	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72482
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
BRD-K03662481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77609
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K12077693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22525
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13061
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.826186
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00667
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968607
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07299
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1061
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00334772
SP100_01_82	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.20708
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73248
LINGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02378
BRD-K31716785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.81789
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19988
DUSP26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56904
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99473
BRD-K54507743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28725
BRD-K29246335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02137
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77875023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22171
Intracellular anatomical structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
BRD-K09434518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42518
BRD-K38118226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71901
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06207
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67931
GTEX-XXEK-0826-SM-4BRWG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
EMTOKA	DepMap CRISPR Gene Dependency	1.0	4.57396
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.034
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1538
BRD-K74056311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26742
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65436
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537034
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05491
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17553
BRD-K32185628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51937
Tonsil cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
NR2F2	ENCODE Transcription Factor Targets	1.0	null
ICC10	DepMap CRISPR Gene Dependency	1.0	4.92666
URB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.061
BC3C	CCLE Cell Line Gene CNV Profiles	1.0	1.42853
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23395
Ras protein signal transduction	GO Biological Process Annotations 2023	1.0	null
fludrocortisone-282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mdamb157	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
NADK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00537459
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03949
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-MEL-3	GDSC Cell Line Gene Expression Profiles	1.0	1.73359
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SE5C-1026-SM-4BRUG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K69775722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50212
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
STK36	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620594
BRD-K61414850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00542
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855007
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948654
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7416
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K44103530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92487
BRD-K01734019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74245
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.40562
BRD-K33710385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46539
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.988428
NFKB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0123697
BRD-K21296995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10594
CASKI	DepMap CRISPR Gene Dependency	1.0	2.62975
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12184916_NVP-BEZ235_MCF7_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15483
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4IJ-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02951
BRD-A19037878_trichostatin A_SKMEL28_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K87176777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29567
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63317
TEAD4_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF552	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68176
BRD-K71592817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95124
TAFAZZIN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608116
SPINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3235
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19502817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02458
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49739
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837133
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53749
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941682
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03262
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF780B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69953
VDR	ChEA Transcription Factor Targets	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06753
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54088
GLUD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00549528
BRD-K34808207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39939
CORL23	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2726
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839784
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K00685640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88873
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UJHI-1426-SM-3DB9C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1339
TRPC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541647
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2065
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02092
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0819
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02874
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1963
CS-2123B (SRC)	NURSA Protein Complexes	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27012
BRD-K77987907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07303
ARL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05959
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3354
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11811
BRD-K49307935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46069
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
cingulate gyrus, parietal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842012
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81793
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922908
FOXRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79371
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SL-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03071
SLC25A24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65729
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3434-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6808
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62934
ANKRD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06158
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94191869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78442
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0531
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0459
MMP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43359
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959784
regulation of phosphorylation	GO Biological Process Annotations 2025	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57571
BRD-K48260102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00124
regulation of protein phosphorylation	GO Biological Process Annotations 2025	1.0	null
CRCGN011_HEPG2_24H:I04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2758
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adenoid cystic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
PDE4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00581872
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13974
JUND_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76713298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13949
BRD-K54956860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05418
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1112
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1291
BRD-A94698726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51187
motile cilium	GO Cellular Component Annotations 2015	1.0	null
UROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81978
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84919
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33049
PRKDC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00606236
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10791
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38993
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73706189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25222
SERPINE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41446
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.898216
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.80037
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28463
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.6589
PBX1	ChEA Transcription Factor Targets	1.0	null
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99589
Lung squamous cell carcinoma_LUSC_TCGA-85-7699-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70625
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.831642
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K24512597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01297
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K55606442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58789
BRD-K19103580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1573
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CST7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00418286
GATA3_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831704
HAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00335576
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8791
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.77328
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07308
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21709
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37838
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37009
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60683
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54173
BRD-K59159285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14143
GTEX-XUW1-0526-SM-4BOP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
BRD-K61555339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05264
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78236
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.898216
single-organism membrane fusion	GO Biological Process Annotations 2015	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20271744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38375
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
FOSL2	ENCODE Transcription Factor Targets	1.0	null
COMMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52471
BRD-K83815133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14364
BRD-K49401787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50814
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38509
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F3-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PABIR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78785
TUBB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88885
BRD-K76640951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12809
AKR1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08115
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49789
PARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23991
TAS1R2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473811
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
BRD-K55160477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65301
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84161
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04674
BRD-K32071534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06829
FOSL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90892
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
STK35	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607809
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92536
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838899
A2M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00451791
HSFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07638
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4023
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826159
SLC1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00345964
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01582
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9936
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9235
HOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12742
MEC1	DepMap CRISPR Gene Dependency	1.0	3.7551
BRD-K92613860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.06476
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.966924
ACN	GDSC Cell Line Gene Expression Profiles	1.0	1.84775
PLCG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507618
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
AMIGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07751
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09058
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88613
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRSK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00591225
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83985
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875432
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46843
SKMEL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97415
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958143
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
organelle organization	GO Biological Process Annotations 2025	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
BRD-K08939002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32501
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.48842
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.953888
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72007
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33087
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	3.23212
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17772
BRD-K66734120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03467
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45512
hsa-miR-4695-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
felodipine-337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27842
CA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540266
Organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876151
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18353
nifedipine-335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MPZL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00497295
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89408
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24166
P63_DEPLETION_GDS2534_63_human_ME180 cervical carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VSIG2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0043615
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.902912
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96336
BRD-K66541877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0098
PAX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86071
GPR137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9252
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14098
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6431_KD_ADAR_SRP268834	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.60268
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
single-organism membrane organization	GO Biological Process Annotations 2015	1.0	null
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853135
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30842998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56451
Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A704	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6769
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Rho protein signal transduction	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA4-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
fusion of sperm to egg plasma membrane	GO Biological Process Annotations 2015	1.0	null
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59957369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02918
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26778
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5888
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55456
Lung squamous cell carcinoma_LUSC_TCGA-77-8133-01A-12R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94652
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05002
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.02798
structural molecule activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-X62O-0126-SM-4E3JN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23297
BRD-K73357447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74981
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
BRD-K96057608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65533
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4555
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Sperm fibrous sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.498
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21231
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.53816
AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48473
FASTK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00824501
BRD-K08811598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19119
CSNK1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52118
Placenta	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5654
BRD-K41006887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05702
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99782
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15505
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7033
BRD-K12710356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29742
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14531
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45773
GTEX-S4P3-1526-SM-3K2AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5429
BRD-K74855272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60021
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.51606
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853816
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19022
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.79788
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K44521151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38959
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52119965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69528
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6995
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4P0-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K58193973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63388
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08748
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06239
SK-MEL-5	GDSC Cell Line Gene Expression Profiles	1.0	1.76206
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
cilium	GO Cellular Component Annotations 2015	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07267
biological adhesion	GO Biological Process Annotations 2015	1.0	null
BRD-A48228341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96773
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4493
EYA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91784
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
BRD-K65725294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25004
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92667
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81018
BRD-K39016838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1454
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849957
BRD-K75426080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33531
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
SP3_01_290	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60838
UACC-62	GDSC Cell Line Gene Expression Profiles	1.0	1.78428
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19618
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58705
MRE11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00636021
cell part	GO Cellular Component Annotations 2015	1.0	null
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
GTEX-WFJO-1126-SM-4LVLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K11804865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35509
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ATRIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536583
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17048
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15469
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K44576681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51383
FAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97908
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08454
reduced male fertility	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3977
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17886
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0189
PMC9314667-Table_1.xlsx-Regulons-SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
CLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01237
LANCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17634
BRD-K99097591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00968
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96501
RPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48794
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01218
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24545
Lung squamous cell carcinoma_LUSC_TCGA-77-6843-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV44-0926-SM-2S1RH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66886
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28552
BRD-K13110695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18182
BRD-K31059261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64688
HCC1500	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63666
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21325
UBAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0070673
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838888
GTEX-T2IS-0226-SM-32QPH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37614
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45632
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9216
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-Q2AG-0326-SM-48U1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11538
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73387
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.788
thorax	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.53012
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94722
PDE1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00853816
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
18438415-SuppData	GeneSigDB Published Gene Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44971
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29M-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95765
OCIMY7	DepMap CRISPR Gene Dependency	1.0	3.55142
ZR75_1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.943325
CDCA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38089
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32437
appendices_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
BRD-K45631723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72836
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09559
BRD-K37698302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01931
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.46938
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05088
RNFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1135
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.99192
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92509
BRD-K23166347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02425
male gamete generation	GO Biological Process Annotations 2015	1.0	null
BRD-K97395479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1256
GTEX-OXRL-0226-SM-3NB18	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K23782109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14608
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.7176
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CASTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01382
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87133
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57691
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.4023
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215086_5_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.524
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54227
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
Prostate adenocarcinoma_PRAD_TCGA-HC-8259-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76563
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1838
CA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84846
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97326
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ZNF467	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65467
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21706
DNMT3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450955
protein localization to cilium	GO Biological Process Annotations 2025	1.0	null
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88468
PMC9822887-41598_2022_27261_MOESM10_ESM.xlsx-HCT116_overlap_TCF7L2_CTNNB1_lo-Unnamed_1_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4R-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42604
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
BRD-K08650286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97699
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17102
Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	2.0154
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DOTC24510	DepMap CRISPR Gene Dependency	1.0	2.42883
regulation of protein modification process	GO Biological Process Annotations 2023	1.0	null
GTEX-QDT8-0626-SM-48TYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18596
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3281
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06391
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4847
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96271
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ASAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02362
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0613
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7536
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MPDU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16912
SEMA3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737026
JOSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00043
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855704
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73818
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896801
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0623
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of phosphorylation	GO Biological Process Annotations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04426746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49887
BRD-K46015322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74205
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
LTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08412
BRD-K31218318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38972
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
IDI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00558403
POLR2A	ENCODE Transcription Factor Targets	1.0	null
KANK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00621821
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A541-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93308
BRD-K22137463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25491
BRD-K45974539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07512
BRD-K98545272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44861
BRD-K25675728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18051
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Zona pellucida receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.453
FOXA1	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25827
BRD-K73669270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54648
Rho protein signal transduction	GO Biological Process Annotations 2023	1.0	null
Perturb_13927_OE_ESRRG_SRP363188	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.84153
cSARS Bat SRBD_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.18811
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03924
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91135
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73654
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60063
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19672
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
BRD-K60517939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26558
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39872
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87546
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
VDR-23401126-LCL-AND-THP1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5038
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.89391
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
HTATIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8938
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4732
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87113
BRD-K79604175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41904
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
wortmannin-404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1199
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10278
BRD-K64536135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87043
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.835481
superior parietal lobule, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20418
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15227
NCO2	DepMap CRISPR Gene Dependency	1.0	3.79862
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06152
OLIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13044
PFKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0040535
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01919
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12819
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42102
BRD-K60946512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11565
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.0165
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04599
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50138
skin	HPA Tissue Gene Expression Profiles	1.0	1.02188
BRD-K06111088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01596
MEL290	DepMap CRISPR Gene Dependency	1.0	3.03999
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11469
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.8938
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.93385
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44233
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14801
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K08753635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.15029
GTEX-P4QS-0726-SM-3NMCZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11337
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76691746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14956
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.103
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25827
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94657
BRD-K33438042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42303
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Lung squamous cell carcinoma_LUSC_TCGA-85-A512-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dg3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.7547
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59642
SCAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1554
16115903-TableS1	GeneSigDB Published Gene Signatures	1.0	null
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58494
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07237
BRD-K37387086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31845
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55204
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
RUNX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519279
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48413
TP53I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10307
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7338542-41389_2020_247_MOESM6_ESM.xlsx-BRN2_2_of_3_DOWN_48_h-Symbol_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6382
LOUCY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
protein heterodimerization activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95375
PNPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94019
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
BRD-K33997327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15331
BRD-K56405136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43721
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56295
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.72
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11259
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SF3B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38846
16491124-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K45307863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20878
C21orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30445
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07207
RELA_01_80	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.70935
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85587
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
CHK2_KD_GSE54268_668_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K47001624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46783
BRD-K43889095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94366
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09086
single-organism localization	GO Biological Process Annotations 2015	1.0	null
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.74947
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64596
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.898216
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950563
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.789209
EFO21	DepMap CRISPR Gene Dependency	1.0	3.00463
cell motility	GO Biological Process Annotations 2015	1.0	null
TPH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687174
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44341
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
BRD-K11874023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45053
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K20895937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55419
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951666
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24133
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04288
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928223
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
plasma membrane bounded cell projection organization	GO Biological Process Annotations 2025	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K09395335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08724
cilium	GO Cellular Component Annotations 2023	1.0	null
CHEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88769
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81085
Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K61661017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12176
BRD-K15028515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8953
SW1783	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78734
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44003
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85195
YARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00693557
CRCGN014_HEPG2_24H:C09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18995
FBXO27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90672
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55234
FABP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00417866
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CARNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70561
MDAPCA2B	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14663
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39461
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06204
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87615
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
TCF7L2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39417
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1779
Transitional cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
Prostate adenocarcinoma_PRAD_TCGA-G9-6354-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMAC-SF	GDSC Cell Line Gene Expression Profiles	1.0	1.65622
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08648
BRD-K02473319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42827
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.14024
BRD-K50271780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69611
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.51239
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5562
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11682
HSPA12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69252
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5981
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K17705318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60725
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38932
SLC9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23935
precentral gyrus, left, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.951997
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.834376
BRD-K40612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04857
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6782
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	2.05798
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
18955564-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
SQSTM1_OE_GDS2653_651_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2933
DMS-273	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47109
EDNRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00636016
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CELA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00751043
BRD-A40010674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20399
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GSE152441,GSE152442_1_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04924
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75096
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC4729482-pone.0146505.s001.xlsx-Sheet1-chRCC_positively_associated_with_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KBTBD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49344
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3021
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85987
SDHD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00594572
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50122
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MGAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00697844
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93395
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.76794
TCF12_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU601	DepMap CRISPR Gene Dependency	1.0	2.6
BRD-K72253829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25262
DB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858821
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
locomotion	GO Biological Process Annotations 2015	1.0	null
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30121
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49955
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.452
HEY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26964
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910706
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892571
RVH-421	GDSC Cell Line Gene Expression Profiles	1.0	2.03783
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45662
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3031
BRD-K73394628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8207
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72068
BL41	CCLE Cell Line Gene CNV Profiles	-1.0	-2.52706
transport	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74653
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10657
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82507
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34548
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28908
VPS4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39018
BRD-K99971319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14789
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2358
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4938
BRD-K55187425_ON-01910_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2BC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55219
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969315
reproductive process	GO Biological Process Annotations 2015	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07957
TIMM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2015
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93119
receptor signaling complex scaffold activity	GO Molecular Function Annotations 2015	1.0	null
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.11516
IL17RE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0064841
Breast	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2787-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MANBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98959
Myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73556
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07194
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0052
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.099
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.43966
CDK11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00454213
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K99847716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75908
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K66907139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22303
BRD-K24308170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75396
ALOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85915
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K83270677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73335
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65522
OVCA433	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29394
PMC3721393-bjc2013326x2.xls-Breast_Cancer_SOX10_Gene_Sig-Unnamed_1_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2905
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95575699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36553
BRD-K59356638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4713
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
THY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610477
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15664
BRD-K03147246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34446
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
BRD-K16305571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11579
NAA35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52684
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31437
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K74515526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05026
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81594
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32604
CRCGN014_HEPG2_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51294
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-PHOX2B-toNode_PHOX2B	Rummagene Transcription Factor Associations 2026	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DYNLRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00404487
SLC30A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10886
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77188
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC6487024-13148_2019_658_MOESM2_ESM.xlsx-S10-Pr_intrc_ADNP-1-Unnamed_1_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.431
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14174
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857538
BRD-K22069962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50884
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E6-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96508
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858534
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920053
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12864
ARH-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
COLO-800	GDSC Cell Line Gene Expression Profiles	1.0	2.64864
NCCMPNST1C1	DepMap CRISPR Gene Dependency	1.0	5.64922
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19302
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12712
BRD-K86102179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21464
PGC1alpha_DEPLETION_GDS4989_283_human_A375P melanoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K76951235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34731
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2194
single organismal cell-cell adhesion	GO Biological Process Annotations 2015	1.0	null
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
acetylsalicylic acid-315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K02403042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23008
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07683
GTEX-RU72-0626-SM-46MUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20173
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900364
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-A04975445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37322
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80644
BRD-K50479239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45298
BRD-K23957028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8712
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
BRD-K51295743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29877
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07327
ras protein signal transduction	GO Biological Process Annotations 2015	1.0	null
CRCGN012_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.48248
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77188
BRD-K40143134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58349
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43729
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16502
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85564
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3894
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.938129
Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
BRD-K11345845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22325
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32174
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K83122599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22237
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
chr3_125973305_G_A_b38	GTEx eQTL 2025	1.0	2.66958
GSE239768,GSE239769_1_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
GSE193993_1_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76437403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17943
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7295
EFR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93849
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62707
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914372
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9745
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09561
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1459
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50887
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K59709341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86133
CDC37L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68259
L33	CCLE Cell Line Gene CNV Profiles	1.0	1.68962
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08899466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4071
BRD-K12702054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45244
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996029
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Viral cardiomyopathy_Myocardial tissue_GSE4172	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.24819
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A496-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15664
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.808838
calcium ion-dependent exocytosis	GO Biological Process Annotations 2015	1.0	null
SH3GL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0975
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90057
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37879
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93812
PIGU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48871
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
OE33	DepMap CRISPR Gene Dependency	1.0	2.46125
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.898216
BRD-K44908610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73644
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8651
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8506
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09483
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34563
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21551
Odontoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
CHSA0011	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980732
ADRB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.004007
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
BRD-K28565184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03222
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.082
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853816
DAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00485444
HNF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99249
PTAFR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0066835
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0667
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74226
protein heterodimerization activity	GO Molecular Function Annotations 2025	1.0	null
EOMES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51252
PANC0327	CCLE Cell Line Gene CNV Profiles	1.0	1.44924
heart muscle	HPA Tissue Gene Expression Profiles	1.0	1.01869
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83024
FEM1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21318
BRD-K03884263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29454
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75338
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SIN3A	ENCODE Transcription Factor Targets	1.0	null
LRP6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557508
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
BRD-K97934318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28882
AMPD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00667548
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838899
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
GSE252958_1_v_0_znf469_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAP3K13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556811
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1926-SM-4DXSG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11174
Dimerization-anchoring domain of cAMP-dependent protein kinase, regulatory subunit	InterPro Predicted Protein Domain Annotations	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K81647247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49342
NPIPB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31099
BRD-K90736603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4284
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32278
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70176
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.583
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
HSP90B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737426
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.07122
C2CD4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32719
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68634
ZFP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91196
placenta	HPA Tissue Protein Expression Profiles	1.0	1.03859
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16051
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07952
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3299
Female accessory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25625
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25761
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4753
PIK3R6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00622742
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15112
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61061
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17388
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23031
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K07013504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10326
JOSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17368
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.0032
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.818
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83739
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A7U0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ICC108	DepMap CRISPR Gene Dependency	1.0	2.35725
NUDT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32856
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29493
GSE215086_1_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74211805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01566
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88117
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50492
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
JUND	ENCODE Transcription Factor Targets	1.0	null
protein heterodimerization activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09663
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SUMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46197
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46691
ASB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80041
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51711
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K54067431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02126
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832702
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839784
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-TFAP4_TFAP4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83768
Basal-Like Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
skmel30	HPA Cell Line Gene Expression Profiles	1.0	1.50916
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21672
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974469
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11735
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911459
BRD-K19603900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15017
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68945
ri1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9373
AS3MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76768
BRD-K80888628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27891
BRD-K09560946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32594
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01833
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39977
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863042
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17869
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26646
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03041
BRD-K78315404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18652
GPATCH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586013
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02697
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
NDUFAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65994
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93546
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39559
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARFRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00371942
GLRB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544429
BRD-K31836496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60545
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876259
NCOA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68929
BRD-K20829034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58339
BRD-K56976888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.2697
TMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2984
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
STAT3	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-A4VK-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33200274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2844
BRD-K07982814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1017
BRD-K14695950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0479
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.00214
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.772
BRD-K48171978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93924
COLGALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62948
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10952
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936801
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5102
EPN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490809
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81685
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996597
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3271
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10516
BRD-K69984954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21133
breast	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACSS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530251
EHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14153
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
BRCA1_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
FASTKD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487558
BRD-K11054415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53701
cSARS Bat SRBD_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.20112
KCNK7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00478033
Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1876
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42102
SYT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00753233
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38294
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.56067
BRD-K10684867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44374
TBX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55736
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
HCC2157	GDSC Cell Line Gene Expression Profiles	1.0	1.81191
GTEX-XYKS-1326-SM-4BRUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05547
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65555
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28475
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3505
Spermatogenic failure 53	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.138
BRD-K31490008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05591
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K87191742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55657
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06366
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81489
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63246
ERCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60649
CCF-STTG1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.01062
BRD-K39206254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.11206
asthenozoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K33098168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32109
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.13987
CRCGN016_MCF10A.TP53.M_24H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03321
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70M-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THEMIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26901
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.05947
BRD-K89532826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35478
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
wm115	HPA Cell Line Gene Expression Profiles	1.0	1.11328
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84678
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52374
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41088
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44261
BRD-K16633334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44854
EP300	ENCODE Transcription Factor Targets	1.0	null
EXD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495447
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07577
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64292
BRD-K52139780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77859
single organism cell adhesion	GO Biological Process Annotations 2015	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.29558
RTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35405
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28544
IFI27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00464799
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44357
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70836
motile cilium	GO Cellular Component Annotations 2025	1.0	null
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03509
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
TMEM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77881
CRCGN009_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.47437
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNKP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00812022
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59429
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2665
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870968
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8902
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37696
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33931
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27412
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93862
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49323
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.791644
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.6238
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-RM2N-0626-SM-48FD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PMC3721393-bjc2013326x2.xls-Melanoma_SOX10_Gene_Signature-Gene_name_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.125
movement of cell or subcellular component	GO Biological Process Annotations 2015	1.0	null
PMC9314667-Table_1.xlsx-Regulons-SOX6_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01103048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0176
breast	GTEx Tissue Gene Expression Profiles	1.0	1.19677
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03039
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03039
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50295
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89617
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19966
SARS-ddORF6_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.69544
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PRDM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11937
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28908
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859668
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K88977610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62793
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16315
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31218
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
CDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48134
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
FANCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32228
HSD17B6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00644069
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XB-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13221
hsa-miR-3115	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
CRCGN009_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11023
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.05299
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18305
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.1641
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73210450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6672
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1473
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67775
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03838
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74346
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974469
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66764
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42029
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47137
BRD-K77713205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34869
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00691
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881605
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26019
BRD-K24494475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02696
SK-MEL-2	GDSC Cell Line Gene Expression Profiles	1.0	1.59955
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
regulation of protein modification process	GO Biological Process Annotations 2025	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65J-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GCKR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00511327
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94459
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888955
BRD-K49635910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2376
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74040368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0756
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29233
TP53_01_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0246
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95111937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11022
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91158
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8646
SKMEL2	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21165
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16021
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78244
BRD-K60127720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14419
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20694
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65737790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.047
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855541
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	1.0	null
secretion by cell	GO Biological Process Annotations 2015	1.0	null
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998169
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20335
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.974
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59842
mammary gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38429
KCTD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490618
BRD-K46639367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7104
cilium organization	GO Biological Process Annotations 2023	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12439337-thnov15p9091s1.pdf-75-ENSG00000124766_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31602570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.29408
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K64704925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04454
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853816
fat_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
BRD-K13817284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39854
ZNF696	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.339
BRD-K49472569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04552
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965448
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22983
SKMEL30	DepMap CRISPR Gene Dependency	1.0	3.96843
BRD-K74916896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20241
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.889
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952774
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.767081
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.812
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04707
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60958
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04308
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43868
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17039
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
BRD-K45112293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15281
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SMIM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11463
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15826
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52852
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08743
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PHF5A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00435647
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9386
spermatogenesis	GO Biological Process Annotations 2015	1.0	null
GYPE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00411127
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1034
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5429
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3466
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CRCGN015_MCF10A.TP53.M_24H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03655
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08964
NCIH196	CCLE Cell Line Gene CNV Profiles	1.0	1.64943
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21367
BRD-K98169006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29264
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A6GG-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Prostate adenocarcinoma_PRAD_TCGA-J4-A6M7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gallbladder	HPA Tissue Gene Expression Profiles	-1.0	-1.17142
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50668
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93348
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99675
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70618
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16545
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23433
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76148
PGAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.01265
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11775
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92682
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0925
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974469
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00702
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42776
STK31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2712
BRD-K00363054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71018
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.856955
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K07414059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97712
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909302
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.34171
MAP3K11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00688263
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17213
BRD-K04468899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29381
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K23432132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19148
STPG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37937
BRD-K62892366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7598
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
PMC9314667-Table_1.xlsx-Regulons-ELF1_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
IMPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71657
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.898216
decreased litter size	MGI Mouse Phenotype Associations 2023	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44943
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873376
BRD-K15343038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1763
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
SLC49A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20887
PPP1R12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
QTRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87103
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16003
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99512
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63246
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0102
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF843	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1833
BRD-K59960811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79242
CELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29496
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K76426411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49489
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13289
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18152
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33453
signaling receptor complex adaptor activity	GO Molecular Function Annotations 2023	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16344
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BLOC1S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74497
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83589
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88726
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26778
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LPS27	DepMap CRISPR Gene Dependency	1.0	2.77292
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.923522
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RDH14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496809
BRD-K04791118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20311
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PDGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10115
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52616
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.861515
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.952128
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JA-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39499927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92243
BRD-K24263752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.8319
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
BCL9L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00388057
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71389
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.203
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE2779	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.92534
BRD-K42457027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91021
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38576
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974469
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84277
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54043
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.841964
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14406
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1474
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21016
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49518
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76693
SNU5	DepMap CRISPR Gene Dependency	1.0	2.38494
ATR_KD_GSE54268_664_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
BRD-K81932943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24187
Oropharynx cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.87861
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.001
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1771
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.41986
EP300_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT144	DepMap CRISPR Gene Dependency	1.0	2.40177
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19219
sperm motility	GO Biological Process Annotations 2015	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.898216
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
BRD-K14306031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.64963
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.39673
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1071
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3214
BRD-K73092207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38593
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.30841
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21284
CENPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17561
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833611
EFO27	DepMap CRISPR Gene Dependency	1.0	2.11656
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3757
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.29516
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940142
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0726-SM-4AD6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980199
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21555
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16255
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85933
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45807
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Mammary luminal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06504
NBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36612
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51484
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3717
MEL-745A cl. DS19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMYD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22957
FUT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487527
BRD-K64797043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58118
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20958
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.747
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78783
BRD-K60444040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07142
BRD-K30038014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15536
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
M14	BioGPS Cell Line Gene Expression Profiles	1.0	0.982142
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97326
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56638
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4711
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26896
BRD-K49040541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23062
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19254
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100283_PCx_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11642
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15826
NCAPG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00398366
KLHL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22185
small GTPase-mediated signal transduction	GO Biological Process Annotations 2025	1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893177
BRD-K93148720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19534
BRD-K94301203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09364
ELF1	ENCODE Transcription Factor Targets	1.0	null
membrane organization	GO Biological Process Annotations 2015	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.954602
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919003
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.49503
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04493
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12712
signaling receptor complex adaptor activity	GO Molecular Function Annotations 2025	1.0	null
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00391
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949207
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853816
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35724
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07474
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839278
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27172
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01829
chlormezanone-5697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNB75	BioGPS Cell Line Gene Expression Profiles	1.0	0.857093
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
BRD-K12784613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20105
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68956
MRPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72006
BRD-K46291400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54705
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PLA2G4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23469
BRD-K98805845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0846
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55352
BRD-K44309337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01276
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.249
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03453
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60142
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24957
signal transduction	GO Biological Process Annotations 2015	1.0	null
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
BRD-K87889654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61866
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54046
Empty sella syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
ASMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44095
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96275
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K41306114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75229
PMC13138062-mmc7.xlsx-DUGs_E2F1_targets-DUGs_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
cellular process	GO Biological Process Annotations 2015	1.0	null
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.886135
plasma membrane fusion	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
secretion	GO Biological Process Annotations 2015	1.0	null
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8984
BRD-K05286676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17656
BRD-K50434315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80998
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
BRD-K89524688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41917
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36128
fludrocortisone-281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56124
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78541
H1-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45873
BRD-K46298074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83123
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6252
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26786
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
LPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601826
PDE6H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00684388
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56319
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08968
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63158
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0222
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02557
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40257
LI7	DepMap CRISPR Gene Dependency	1.0	3.12828
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21955
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3027
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7075
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K22537050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09139
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
STAT5A_02_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K56131419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81353
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09443
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytokinesis	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05043
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3023
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.32087
organelle organization	GO Biological Process Annotations 2023	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38496
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06026
TMEM107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78639
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846926
GATA6-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
17389037-Tab3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K72609445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5021
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
BRD-K27226238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05882
GTEX-T6MO-0326-SM-32QOK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10457
BRD-K84439371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23531
PEX11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57562
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27643
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979048
CRCGN011_HEPG2_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20315
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82006
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858726
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5721
PCCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00644956
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98382
GCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53504
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K88472400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36382
OCIC4P	DepMap CRISPR Gene Dependency	1.0	2.10036
NMB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00510435
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
protein localization to cilium	GO Biological Process Annotations 2023	1.0	null
UBALD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87046
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71403
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21884
FOXRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00843
BRD-K78659596_MLN2238_SKMEL28_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18551
COR-L23	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85387
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07431
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56951
KPNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10501
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46596
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01904
regulation of protein phosphorylation	GO Biological Process Annotations 2023	1.0	null
GSE220629_0_v_1_foxp3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11867
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8667
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928529
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.41693
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66674
BRD-K47754225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01592
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0925
BRD-K13130949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41702
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.39875
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18321
SNU182	DepMap CRISPR Gene Dependency	1.0	2.3022
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3414
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36396
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60143
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.87089
BRD-K54132860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22701
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891908
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
phenacemide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.188
BRD-K76937233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09528
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93961
TCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00663257
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SK-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DTHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00530863
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
MEWO	CCLE Cell Line Gene CNV Profiles	1.0	2.23323
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BL342 (MEN1)	NURSA Protein Complexes	1.0	null
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20694
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39323
BRD-K75041866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86592
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
AKAP3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01891
OCI-M1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-11/NTKO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.648
GTEX-SE5C-0326-SM-4BRWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38667
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898211
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.74395
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88087
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27091
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K67665252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89706
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85391
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91606
hsa-miR-3591-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
SF295	DepMap CRISPR Gene Dependency	1.0	3.32853
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IST-MEL1	GDSC Cell Line Gene Expression Profiles	1.0	1.66414
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ODC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34512
CAL-72	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
BRD-K37912617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34949
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14146
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.35748
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881935
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
dihydroergotamine-4502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
C1orf216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04149
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48425
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K45057266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09572
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32001
BRD-K50272743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2198
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45774
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42084582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3007
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A101D	GDSC Cell Line Gene Expression Profiles	1.0	1.43213
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32177
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62541003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80235
SU-DHL-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46913
BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910929
BRD-K97318603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15578
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
BRD-K20028734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.19411
smallintestine_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86685
BRD-A01717111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1887
ACIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91029
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41998
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762867
Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950247
BRD-K24178822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0154
SERTAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64899
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.921322
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3536
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79796
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49621
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.28517
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11092
RASL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13551
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52136059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04835
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.782732
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31037
BRD-K67817697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60922
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86038
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95653
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.146
GBP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0038899
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5636
BRD-K83752863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04751
TSPAN33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03293
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.32426
FDFT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00354521
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10657
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
ZNF839	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6601
BRD-K97393725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51987
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K33653343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47653
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50364
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.27939
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K01039605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79708
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85352
FAM47E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44114
BRD-K77935284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25185
protein localization to organelle	GO Biological Process Annotations 2025	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GIMAP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508535
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947595
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39933
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03881
LS180	DepMap CRISPR Gene Dependency	1.0	4.44059
IFNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00630212
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926443
BRD-K02208014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14781
NDFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07413
Prostate adenocarcinoma_PRAD_TCGA-EJ-5521-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70972
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09197
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8055
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8717
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3466
BRD-K20520611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06027
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826781
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29626
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91306
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
BRD-K91397206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68446
BRD-K11504463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13643
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52713598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11855
ZNF217	ENCODE Transcription Factor Targets	1.0	null
BRD-K59263278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18228
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90128
quercetin-283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873294
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935538
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8012
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05207
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990555
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88474
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0255
BRD-K46588240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.813
hsa-miR-629	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38284
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.03859
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22077
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15254
BRD-K72314068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12457
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
NF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86499
BRD-K72591075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28307
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90626
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11204
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19758
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930388
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.68438
2-iodomelatonin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12437
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.152
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17012
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79531
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55457
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49502
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949796
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell adhesion	GO Biological Process Annotations 2015	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2466
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51484
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DJM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57256
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08698
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05186
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4195
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948018
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80399
GTEX-XV7Q-1726-SM-4BRUU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96722
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33298
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973851
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46846
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TEAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17686
ZNF322	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47478
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
BRD-K52391588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2898
BRD-K03440991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32466
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45512
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994518
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90768
plasma membrane bounded cell projection organization	GO Biological Process Annotations 2023	1.0	null
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51178
BRD-K27331198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19232
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13875
ERCC6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68397
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1794
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75641
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3041
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24133768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.10118
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95509
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923639
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26685
TMOD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497568
CRCGN008_HEPG2_24H:D06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3952
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65416
BRD-A40504327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24192
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43794
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29816
Pancreas	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K11477112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47062
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1057
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54736
DMS53	DepMap CRISPR Gene Dependency	1.0	3.68375
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-RTLS-0226-SM-2TF5E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75205131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20596
BRD-K73451279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11188
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02729
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K09227140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09382
GTEX-S4P3-1326-SM-4AD6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28645
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
rho protein signal transduction	GO Biological Process Annotations 2015	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.831728
chr3_125967918_T_A_b38	GTEx eQTL 2025	1.0	1.07096
BRD-K48861177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18798
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.6245
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84269
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12307
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23198
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71812
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879979
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13995
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.186
DCUN1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76639
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1561
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47658
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.63422
MAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10201
BRD-K65633211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44789
BRD-K26957826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02438
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
localization	GO Biological Process Annotations 2015	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57176
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17246
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03785
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8971
GTEX-TMMY-0726-SM-33HBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03406
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ATP1A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00850098
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874096
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUSD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00590537
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BTBD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83057
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.20767
TMEM203	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2204
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946649
GATA3	ENCODE Transcription Factor Targets	1.0	null
APH1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475676
BRD-K90644597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73139
UACC257	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
RANBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57626
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K06611347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.53761
BRD-K02241673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84162
BRD-K03304013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27752
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82562
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46588
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7851
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87372
BRD-K21479004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10844
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.95815
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33751
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58548
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
FCRLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00552886
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03772
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46128
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0552
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69134
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52405
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824436
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31406
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0672
motile cilium	GO Cellular Component Annotations 2023	1.0	null
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.13151
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K86104966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6789
chloroxylenol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75156
Seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
BRD-K56381552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22088
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23845
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79545
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77258
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.622
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81051
ZIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13596
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60593
RXRA	ENCODE Transcription Factor Targets	1.0	null
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93431
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0451
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35856
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6071
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39208
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
BRD-K83783925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25754
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.5025
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06994
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
16636340-Table2	GeneSigDB Published Gene Signatures	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
ELAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
MBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10047
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5902
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39201
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0643
PCCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44838
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86204
HCC1395	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3202
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5747
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94135
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5353
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86119
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0555
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
BRD-K34710061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02622
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4656
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.39151
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57733
Adrenocortical carcinoma_ACC_TCGA-OR-A5KO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02703
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933616
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46467
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
RBFOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79902
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
TOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80321
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869669
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
GATA3_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31679
BRD-K34604755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.779
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9632
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59134
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DIDO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00651583
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K90048234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48176
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2312
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851439
BRD-K60794504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16291
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96201
EZH2_DEPLETION_GDS2445_117_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CYTH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25375
BRD-K42247636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07516
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.916768
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
BRD-K63803358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71244
BRD-K53552465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47105
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9214
BRD-K51579714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20627
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGR-1	GDSC Cell Line Gene Expression Profiles	1.0	1.50143
cellular process involved in reproduction in multicellular organism	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC39A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03733
BRD-K83963101_MLN-8054_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12271
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex scaffold	GO Molecular Function Annotations 2015	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09277
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NO-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69772
HCC1187	DepMap CRISPR Gene Dependency	1.0	6.23841
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.849562
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	1.62097
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
BRD-K24170552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07536
Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05335635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35119
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K40532221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05489
CRO-AP2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48331
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
small gtpase mediated signal transduction	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16391
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9518
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86692
ARFGEF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0057879
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68454
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25452
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236939
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.91138
BRD-K16570418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.68293
TAF1	ENCODE Transcription Factor Targets	1.0	null
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3182
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K06284373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40551
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48278
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60321
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47064511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07575
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42102
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83881
BRD-K98611274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16899
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.05387
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46753
BRD-K82785545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10636
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936999
BRD-K73200916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03814
BRD-K42557763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31398
ING4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573514
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K88964321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21909
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0983
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857245
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30294
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SOAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484861
FOXN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00643505
membrane fusion	GO Biological Process Annotations 2015	1.0	null
A375SKINCJ3	DepMap CRISPR Gene Dependency	1.0	11.9592
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
TP53BP1_KD_GSE54268_669_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K34445019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13853
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
multicellular organismal reproductive process	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31157
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
CRCGN014_HEPG2_24H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04973
NR1I3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00438915
UBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23788
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2656
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.963574
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25919
BRD-K42805893_HG-14-8-02_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89232
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974469
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
WM-115	GDSC Cell Line Gene Expression Profiles	1.0	1.46414
establishment of localization	GO Biological Process Annotations 2015	1.0	null
BFSP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00769402
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.855782
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97326
MAP2K4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546085
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34771
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06445
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
A361	BioGPS Cell Line Gene Expression Profiles	1.0	0.915343
BRD-K96254487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4152
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12826
17910759-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75618633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21848
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80225
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21418
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A449-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17494
496100607_TCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50596
Lobular carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.875
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
BRD-K06226868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43984
UBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47445
PMC6366065-13075_2019_1816_MOESM1_ESM.xlsx-DOD_Skin_imputed_log2_median_ce-Name_PIN1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869586
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Eye-melanocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.141643
chr3_125970584_T_A_b38	GTEx eQTL 2025	1.0	1.00152
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4054
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.872
MDAMB415	DepMap CRISPR Gene Dependency	1.0	3.19961
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.55293
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.01538
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19266588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17943
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16419
Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43214
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975025
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42287
BRD-K17180926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3906
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2516
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37209
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92097
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
DNASE1L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538873
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37255
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938488
LRRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472901
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87887
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09834
BRD-K27914478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41439
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.03859
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2156
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33064
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42133
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3466
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1544
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00988
GCG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00620556
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83335
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71306
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891863
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.55566
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.07358
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01284
BRD-K56893290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44383
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67433
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37631
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Rectum adenocarcinoma_READ_TCGA-AH-6544-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970903
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16754
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
MAP3K9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00436551
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
CCN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00427238
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830986
CDHR3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00758674
Myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
BRD-A12372458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07587
cilium	GO Cellular Component Annotations 2025	1.0	null
ventral lateral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01813
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7757
BRD-K41946683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09469
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91577886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47477
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68580555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01416
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.2602
CDCA7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61215
BRD-K06320746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41347
RDES	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41831
SLC35F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10008
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7612
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
BRD-K53936012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58053
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88456
DK-MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.64884
ovary	HPA Tissue Gene Expression Profiles	-1.0	-1.17142
chr3_125987169_G_A_b38	GTEx eQTL 2025	1.0	1.83184
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54416
ALKBH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09161
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19716
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01598
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.03859
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OGFOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14849
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21469
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1593
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57886
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858604
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59904
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.146
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24505
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36761
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
SLC5A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38869
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71864
SK-MEL-28	GDSC Cell Line Gene Expression Profiles	1.0	1.52707
BRD-K47794327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52376
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TSHZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83656
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95441
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3475
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18522
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72359187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87227
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K69387464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51839
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927241
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19754
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11766
PPFIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92597
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
cell cycle process	GO Biological Process Annotations 2015	1.0	null
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21284
SOBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00573957
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06124
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00343
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849761
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.977188
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.86152
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73739802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22678
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63055
protein binding	GO Molecular Function Annotations 2015	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
c32	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
VDR-24763502-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cytoskeleton-dependent cytokinesis	GO Biological Process Annotations 2025	1.0	null
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04199
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21294
Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.03859
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.921187
STX11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00648482
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09076
CTCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23693
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82559
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47518
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64904523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87372
CRCGN017_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91355
FBXO33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
WDFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36178
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.201
SW948	DepMap CRISPR Gene Dependency	1.0	6.39928
MAMDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3081
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84879982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07456
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53019
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11C-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K79157816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13234
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41408
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39794
BRD-K92241728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22428
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83396
BCAP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89928
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25U-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97232
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98126
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08854
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32195
GSE183113_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOLH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067802
TCF12	ENCODE Transcription Factor Targets	1.0	null
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62788
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970368
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85926
CCKBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48358
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51246
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
VDAC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00605267
GTEX-XUJ4-1926-SM-4BOOV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981297
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68648
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
C84	DepMap CRISPR Gene Dependency	1.0	3.64692
BRD-K62692910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61634
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
hsa-miR-3613-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K45628030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18901
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08188
BRD-K83994491	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34937
SPAG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38639
BRD-K72379955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09997
BRD-K25013674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.62694
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96574
GPR171	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00541974
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40629
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03039
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04511
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K86884344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21973
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74393
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02947
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
PMC13138062-mmc7.xlsx-DUGs_ESR1_targets-DUGs_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81151
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.111
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00257
BRD-K31510624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28498
LPS141	DepMap CRISPR Gene Dependency	1.0	2.43161
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64818
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21587
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72752
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.934551
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.901597
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K40816903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86017
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07526
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4637
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18587
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K60076175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63808
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27891
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.146
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64144
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06137
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7-Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903398
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867692
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27576
496100359_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29777
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20694
BRD-K81931105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36796
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39165
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CC2D1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63004
MACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08599
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10459972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48405
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03811
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.878
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82524
BRD-K35035851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5197
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3047
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
TMEM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36752
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850539
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0377
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45187
single-organism process	GO Biological Process Annotations 2015	1.0	null
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
BRD-K68562280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10161
Megalocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17774
GTEX-X4EP-2926-SM-3P5YQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847699
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.870377
HCE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9721
NCIH2081	CCLE Cell Line Gene CNV Profiles	1.0	1.65366
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50124
ZDHHC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62019
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93229
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0748
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24371
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83865
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07182
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
PEPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86401
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882527
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87021
KCNE4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00518411
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06315
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900592
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08017
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96452
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
biological regulation	GO Biological Process Annotations 2015	1.0	null
BRD-K22957824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76571
BRD-K71345532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08821
TBRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5025
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
ADSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74564
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.8913
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05002
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K55018894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15856
MLNR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529131
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868319
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0515
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1023
BRD-K68984041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35054
SW962	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33286
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12468
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9368
UACC62	BioGPS Cell Line Gene Expression Profiles	1.0	1.0603
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938488
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43341819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22074
EZH2	ENCODE Transcription Factor Targets	1.0	null
U-87-MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63007
BRD-K61259788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30558
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
GTEX-SE5C-2126-SM-4BRUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978085
BRD-K14070721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04862
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43594798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58009
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40945
DANG	CCLE Cell Line Gene CNV Profiles	1.0	1.36091
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
Cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
small intestine	HPA Tissue Gene Expression Profiles	-1.0	-1.17142
MAGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63785
BRD-K22377875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11728
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44238
CRCGN015_MCF10A.TP53.M_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.33333
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39013
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93611
GTEX-XV7Q-2626-SM-4BRVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864866
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
UACC-257	GDSC Cell Line Gene Expression Profiles	1.0	1.66585
PPARD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00342942
BRD-K37865854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14024
RIPK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35865
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28839
salivary gland	HPA Tissue Gene Expression Profiles	1.0	2.24445
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.896999
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31214
NCIH520	CCLE Cell Line Gene CNV Profiles	1.0	1.38165
Mammary gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZDHHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96565
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0466
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94385157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32539
BRD-K25710391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13885
CRCGN013_HEPG2_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10366
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89271
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bulbourethral gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3729
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.534
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
BRD-K74842791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30043
BRD-K53901855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7638
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.845
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19472
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0731
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974469
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04425
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
GTEX-R55E-0326-SM-48FD2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.86507
protein localization to organelle	GO Biological Process Annotations 2023	1.0	null
BRD-K68985225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32762
RBM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21769
BRD-K68008192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81059
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56966
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42631
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
SORD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76714
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53019
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
c2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52843
Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77052
LB2518-MEL	GDSC Cell Line Gene Expression Profiles	1.0	1.63307
PDXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5207
KMH2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.93187
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06314
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4368
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00478
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50002
CCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61385
OSR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6921
COQ8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42339
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86407
SIGLEC9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626436
BRD-K04192407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21447
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCC-JW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19199
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43075
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.64478
NICN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00635058
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
exocytosis	GO Biological Process Annotations 2015	1.0	null
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30897
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.83368
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46258
ZNF454	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.36
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K16698502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11125
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DXO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00940042
BRD-K62698674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03705
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35213218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18538
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944482
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
WM88	DepMap CRISPR Gene Dependency	1.0	2.19854
SLC6A12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596994
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.012
BRD-A01643550_PREDNISOLONE ACETATE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE140651,GSE140653_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84517
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1894
TOMM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7393
BRD-K01749472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35548
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1602
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01177
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12902
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97326
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12712
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.81515
FHIP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048561
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03127
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.47724
WDR83OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94333
SLC22A31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08684
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25459
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86174
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3229
cilium organization	GO Biological Process Annotations 2025	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G402	DepMap CRISPR Gene Dependency	1.0	2.49494
BRD-K34024207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45846
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3463
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00479
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850713
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62097
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1279
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14033
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08322
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPHK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00598331
BRD-K53308430_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.944627
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	0.904366
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3895
cytoskeleton-dependent cytokinesis	GO Biological Process Annotations 2023	1.0	null
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905635
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70621