association	dataset	threshold value	standardized value
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
attenuation of retinal blood vessels	HPO Gene-Disease Associations	1.0	null
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55489
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840894
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.909304
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60362
C2BBE1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900646
Perturb_13072_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.48242
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
Microphthalmos	DisGeNET Gene-Disease Associations	1.0	null
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.69451
neuron degeneration	MPO Gene-Phenotype Associations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72018
GB1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22472
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.134712
SNU-449	GDSC Cell Line Gene Expression Profiles	1.0	1.43536
GTEX-N7MS-0326-SM-4E3K2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04266
positional foot deformity	HPO Gene-Disease Associations	1.0	null
Perturb_15651_OE_Ccnj_DRP008918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.54477
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853967
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838729
BRD-K67591072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39693
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15578
glaucoma	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08657
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933956
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.075887
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54889
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09083
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.1792
hereditary retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0109
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54269
ZNF761	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23663
Pancreatic Cyst	DisGeNET Gene-Disease Associations	1.0	null
Retinitis pigmentosa 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.339
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85696
TFE3	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fourth ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250301
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21724
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70597
abnormal photoreceptor inner segment morphology	MPO Gene-Phenotype Associations	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.086632
abnormal somatic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5276-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU81	CCLE Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39332
abnormality of the thumb	HPO Gene-Disease Associations	1.0	null
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.602912
BRD-K39419290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07413
Perturb_17281_KO_Gja1_SRP247546	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.78862
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	1.42912
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Neural tube defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Seckel syndrome 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.20429
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.947765
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.09136
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Reduced Visual Acuity	DisGeNET Gene-Phenotype Associations	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4877
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871319
Superior temporal sulcus banks volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27024
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6783
BRD-K13130949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70623
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18535
response to stimulus	GO Biological Process Annotations 2015	1.0	null
hypertelorism	HPO Gene-Disease Associations	1.0	null
Photoreceptor Degeneration	DisGeNET Gene-Disease Associations	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10556
Congenital Cerebral Hernia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K12642652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1804
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
Macular holes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23712
BRD-K29726765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0305
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978607
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69441
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0047
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	2.20037
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05940224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16724
Perturb_1812_KO_N4bp1_SRP255180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.1478
KP3	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
SNU840	DepMap CRISPR Gene Dependency	1.0	3.98074
BRD-K97045804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09514
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K76628522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12541
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831557
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07408
BRD-K87191742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34058
abnormality of the 5th toe	HPO Gene-Disease Associations	1.0	null
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935433
Fibrosis Of Pancreas	DisGeNET Gene-Disease Associations	1.0	null
Cone dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.87
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04337
preaxial hand polydactyly	HPO Gene-Disease Associations	1.0	null
Perturb_1685_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.78755
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.100056
Ulnar Polydactyly Of Fingers	DisGeNET Gene-Disease Associations	1.0	null
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
DAUDI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33334
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73619
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1233
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76929
BRD-K13411423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52405
Perturb_5253_KD_Snd1_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.321545
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33193
BRD-K91490997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02395
short photoreceptor inner segment	MGI Mouse Phenotype Associations 2023	1.0	null
Retinitis Pigmentosa	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93936
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04013
abnormality of the cerebral white matter	HPO Gene-Disease Associations	1.0	null
abnormality of the hard palate	HPO Gene-Disease Associations	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49086
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86371
Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174361
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.48048
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4716_KD_Hnrnpu_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.63673
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
NCI-H1299	GDSC Cell Line Gene Expression Profiles	-1.0	-1.97457
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11329
Trichocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
anencephaly	HPO Gene-Disease Associations	1.0	null
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36043
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2892
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73689413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.363
DHX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13618
MYC	ChEA Transcription Factor Targets	1.0	null
Perturb_15662_KD_Hnrnpk_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.63122
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3276
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51997
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22166
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.07812
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K64376499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47869
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.172
SUDHL5	CCLE Cell Line Gene Mutation Profiles	1.0	null
Perturb_1756_KO_Ripk3_SRP226420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97692
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34714
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63203
Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70717477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06361
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24038
Perturb_1740_KO_Usp15_SRP290189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.00849
Prostate adenocarcinoma_PRAD_TCGA-Y6-A8TL-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
neuron development	GO Biological Process Annotations 2015	1.0	null
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0813
BRD-K49584663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31902
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K72435943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27901
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0164
PF382	CCLE Cell Line Gene Mutation Profiles	1.0	null
Growth Disorders	CTD Gene-Disease Associations	1.0	1.15729
retina	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00476
Abscission zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09517
Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2592
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Cranioectodermal dysplasia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984273
Low Tension Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_17824_KO_Kansl3_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.26755
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05232
Abnormality Of Retinal Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
BMPR2	MSigDB Cancer Gene Co-expression Modules	1.0	null
Leber congenital amaurosis 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.555
Pathologic nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.975
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13186
ciliary part	GO Cellular Component Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16276539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12488
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_macaque_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
17483317-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863444
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Choroidal sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848066
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4075
abnormal rod and cone electroretinograms	HPO Gene-Disease Associations	1.0	null
BRD-K29707171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06251
hydroquinine-2767	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
retinal rod cell development	GO Biological Process Annotations 2025	1.0	null
Perturb_11062_KO_Jup/Ctnnb1_SRP304535	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.188
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36666
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8667
DMS79	CCLE Cell Line Gene CNV Profiles	1.0	1.51618
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbit lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
Ciliary necklace	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.699
developments	GeneRIF Biological Term Annotations	1.0	null
Obsolete Rod-Cone Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00255
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.914531
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07308
Liver Diseases	CTD Gene-Disease Associations	1.0	1.33612
disease	GWASdb SNP-Disease Associations	1.0	0.024451
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.871984
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ciliary basal body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.539
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1412
Abnormality Of The Optic Disc	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_14868_KO_PU.1_SRP166067	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.58604
BRD-K66973998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19617
GSE190235_1_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.053
GSE110178_5_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45049
KASUMI6	CCLE Cell Line Gene Mutation Profiles	1.0	null
mIMCD-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.332
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02045
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.0569
Stargardt disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.416
BRD-K32881384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70433
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32711
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05425
distributed	GeneRIF Biological Term Annotations	1.0	null
consanguineous	GeneRIF Biological Term Annotations	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.38562
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53323
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85942
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.51386
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05791
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78822
BRD-K65633211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78005
Perturb_20_OE_Smarca5_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.1496
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041636
Talipes	DisGeNET Gene-Disease Associations	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89749
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.087475
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958509
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
achromatopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.487788
Retinoschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.145
abnormality of the face	HPO Gene-Disease Associations	1.0	null
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05863
HT55	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.31936
decade	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5488
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.63317
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01118
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.826
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.71205
PRKAG3_Mutation (R225Q)_GSE4067_390_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2376_KD_Cdk8_SRP292215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.39743
20630075-AF-3	GeneSigDB Published Gene Signatures	1.0	null
Orbital Separation Excessive	DisGeNET Gene-Phenotype Associations	1.0	null
angle-closure glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.459751
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pigmented paravenous chorioretinal atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.4
susceptibility	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22954
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89985
photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.447259
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Height	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
CTCF	ENCODE Transcription Factor Targets	1.0	null
abnormality of the forehead	HPO Gene-Disease Associations	1.0	null
BRD-K85559506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01812
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43549
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74724
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878313
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848797
BRD-K52872067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28512
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.985314
GTEX-XV7Q-1626-SM-4BRWC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888269
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23885
u87	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
abnormality of the 5th finger	HPO Gene-Disease Associations	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SMAD1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07559
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.493
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.703
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25611
BRD-K37592272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12278
CAV1_KO_GDS3551_366_mouse_mouse heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21716
SLC22A31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08684
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.62508
situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.409787
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30533903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03768
EPHA7	MSigDB Cancer Gene Co-expression Modules	1.0	null
changes	GeneRIF Biological Term Annotations	1.0	null
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15919
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924484
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62168
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19325
congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.43753
MKN1	CCLE Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3325-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44629
Perturb_1382_KO_Sdc1_SRP286584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.52303
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16855
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_4810_KO_Atp2b4_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.96539
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920192
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03225
Perturb_5252_KO_Klf2/Snd1_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.990779
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51408
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882785
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05458
diphenylpyraline-3640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_7910_KO_CLP1_SRP367036	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358546
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31306
Nephronophthisis 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
BRD-K74712962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13286
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865479
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB3A	MSigDB Cancer Gene Co-expression Modules	1.0	null
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2183
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1699
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.188
Perturb_12881_KO_Mof_SRP073926	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.65543
PMC4920181__F5	PFOCR Pathway Figure Associations 2024	1.0	null
microtubule organizing center part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.490539
BRD-K74834319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39915
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.593
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16196
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426872
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52015
CDH4-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
abolished electroretinogram (erg)	HPO Gene-Disease Associations	1.0	null
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12618
BRD-K76492619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5469
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946996
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12776
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0379
Leber congenital amaurosis 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.823
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42294
Perturb_15630_KD_Ctnnb1_SRP130920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45817
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03425
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06385
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19841
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.187
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31124
dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404039
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5353
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20647
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842422
globe disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05050615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75663
Retinoblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
BRD-K78252315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44104
Mpk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83654
cleft palate	HPO Gene-Disease Associations	1.0	null
various	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TY-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64546
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.044
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3147
Perturb_2020_KO_Parp2_SRP243891	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.69121
Dementia, Vascular	DisGeNET Gene-Disease Associations	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3375
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65796
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27614
dilazep-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58986
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868363
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38623
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FW-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21612
Perturb_5140_KO_Rn7sk_ERP002405	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38478
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48715
Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17339_KO_Plag1_SRP095348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.46534
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96278
Perturb_3089_KO_Fkbp5_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.9287
Perturb_17514_KO_Sh3gl1_SRP315284	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.56258
breast	HPA Tissue Protein Expression Profiles	-1.0	-0.796587
Perturb_1743_KO_U2af1_SRP297129	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Prostate adenocarcinoma_PRAD_TCGA-M7-A725-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16084_KO_Nfya_SRP270915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.45667
phenotype	GeneRIF Biological Term Annotations	1.0	null
PMC12486367-Supplementary_Data2.pdf-68-ZNF766_ZNF766	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0343
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14058
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.887927
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.796587
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974202
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.444
STAT3_01_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59143
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.9793
ML1	CCLE Cell Line Gene CNV Profiles	1.0	1.78905
Lens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.509
abnormality of the nasal dorsum	HPO Gene-Disease Associations	1.0	null
769P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56944
KO52	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Shoot tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.851
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44292
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11617
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.275
BRD-K40248932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42446
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Hereditary choroidal atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
CEBPA	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46319
Anencephaly	DisGeNET Gene-Disease Associations	1.0	null
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52771
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	1.55765
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53538
abnormality of the corpus callosum	HPO Gene-Disease Associations	1.0	null
GSE163052,GSE163198_4_v_7_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.835
abnormality of the retinal pigment epithelium	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3867
Perturb_13218_KO_Dres1_SRP127601	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.71833
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-8601-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.37801
Perturb_3416_KO_Cdx2/Apc_SRP093647	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3825
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5141_KO_Rn7sk_ERP002405	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43629
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.27814
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884725
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMCD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.359
BRD-K30632097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76274
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6917696-41467_2019_12917_MOESM9_ESM.xlsx-Leber_congenital_amaurosis-CRX_CRX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88699
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14267
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TYKNU	DepMap CRISPR Gene Dependency	1.0	2.82764
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.857574
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86692
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.80319
BRD-K76960042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13641
PMC4823079-oncotarget-07-2889-s002.xls-Feuil3-Supplementary_table_1_DEK_and_WT1-dependent_AEUs_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
vivo	GeneRIF Biological Term Annotations	1.0	null
COLO-205	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2484
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67774
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33336
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07207
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
Perturb_12012_KO_B2_Mm2_SRP374407	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.20361
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29756
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03541
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845967
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rod-Cone Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventromedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29173
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33527
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50875
gucy2d	GeneRIF Biological Term Annotations	1.0	null
BRD-K12034365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78101
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11421
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.75075
CHD1	ChEA Transcription Factor Targets	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.7439
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.097029
nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.27955
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30052
hearing impairment	HPO Gene-Disease Associations	1.0	null
Cone-Rod Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.98683
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5075-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48949
abnormality of the iris	HPO Gene-Disease Associations	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23742
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.962
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08346
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2457
BRD-K77417197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39236
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02622
spleen_3b	HPA Tissue Sample Gene Expression Profiles	1.0	0.940846
BRD-K38211037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07895
molecular	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09878
Amaurosis	DisGeNET Gene-Disease Associations	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.920432
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26249
abnormality of corneal thickness	HPO Gene-Disease Associations	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.74368
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.28548
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0327
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65396
PMC9669639-mmc3.xlsx-NRLonly-degs-207-Single_cell_RNA-seq_differentially_expressed_genes_between_control_versus_USH1B_NRL_cells_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.97511
ATIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59339
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Situs Inversus Totalis	DisGeNET Gene-Disease Associations	1.0	null
an3ca	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
Lung adenocarcinoma_LUAD_TCGA-78-7143-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.022
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5897
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04399953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82192
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987722
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06143
Wes	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
MAPK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25449
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17405
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30733
Unidirectional Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
laurence-moon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.18496
Blue cone monochromacy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
HKA1	DepMap CRISPR Gene Dependency	1.0	2.15838
BRD-K81925504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46462
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11479
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9066
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.853613
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.36179
optic atrophy	HPO Gene-Disease Associations	1.0	null
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
Inflammation	CTD Gene-Disease Associations	1.0	1.28395
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848066
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.99028
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838824
Cornea plana	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45307
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25103
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32005
Mesothelioma_MESO_TCGA-TS-A7OY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A704	CCLE Cell Line Gene Mutation Profiles	1.0	null
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5186
BRD-K74978191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23138
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89918
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30473
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.830468
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38931
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1239
GTEX-NPJ7-1326-SM-3MJHO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933251
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05821
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41332
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.53628
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Asphyxiating thoracic dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.945
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-2.37698
cone-rod dystrophy 13	OMIM Gene-Disease Associations	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.127
mantle zone of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05519
genetic	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71154829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26325
cell projection part	GO Cellular Component Annotations 2015	1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-2.72363
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02717
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00737
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72007
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.02659
rpgr	GeneRIF Biological Term Annotations	1.0	null
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01681
Bowing Of The Long Bones	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_15776_OE_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45698
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46571
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42058
LN319	Achilles Cell Line Gene Essentiality Profiles	1.0	1.6253
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02045
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923619
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06918
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
dextrocardia	HPO Gene-Disease Associations	1.0	null
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926206
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_CHD1_19587682	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920992
Cone-rod dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
Perturb_5813_Mut_U2af1_SRP266807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.10525
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938385
HUP-T3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67089
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060374
THP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.741
decreased central vision	HPO Gene-Disease Associations	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046986
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15114
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pbmc cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175689
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01834
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16964
aplasia/hypoplasia affecting the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889888
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10536
Perturb_14566_KO_Got2_SRP348541	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.6908
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20335
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25266
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961863
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0625
HCC1954	DepMap CRISPR Gene Dependency	1.0	6.30888
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02828
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30646
Perturb_218_KO_Uba6_SRP389127	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.60352
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
Low tension glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839468
Meckel syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.198
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67958
PDCD6IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30557
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05793
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952165
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893589
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Conjugate Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.78354
Ocular albinism 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
COLO792	CCLE Cell Line Gene Mutation Profiles	1.0	null
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.869
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85016
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6916
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7649-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98356
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952165
BRD-K12239796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74594
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37687
abnormality of the vasculature	HPO Gene-Disease Associations	1.0	null
abnormal rod electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
Root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.434
cerebellar vermis hypoplasia	HPO Gene-Disease Associations	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960077
Sclerocornea	DisGeNET Gene-Disease Associations	1.0	null
BRD-K29935988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36796
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4201_KO_Scn1a_SRP133962	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.16646
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17272
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69296
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12306
Aplasia/Hypoplasia Of The Tongue	DisGeNET Gene-Phenotype Associations	1.0	null
bovine	GeneRIF Biological Term Annotations	1.0	null
BRD-K53717076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01162
OCUBM	DepMap CRISPR Gene Dependency	1.0	2.74322
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.174424
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09993
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958509
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44639
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_5_CXCL10-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85523
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33173
KLK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19431
red-green color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87792
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53975
MET_knockout_264_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.61328
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56923
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4076-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17062413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04705
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89351
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.574
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03324
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16797
studies	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50338
Perturb_13263_KO_chr7_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.7816
GSE188599_1_v_10_resolvin e1_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916261
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28146
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.73205
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meckel syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
Fundus albipunctatus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.087
dandy-walker malformation	HPO Gene-Disease Associations	1.0	null
BRD-K95943192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2745
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Leber congenital amaurosis	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
BRD-K86004174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22306
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01197
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48949
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12378
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24201
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06997
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZR-75-30 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1366
GTEX-RU72-2226-SM-46MUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01831
GTEX-S341-2026-SM-2XCAA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Anophthalmos	DisGeNET Gene-Disease Associations	1.0	null
Respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.46465
Retinitis pigmentosa 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
hsa-miR-4760-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.717
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
PLEKHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08718
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53031
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2172
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
peripheral blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110229
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02238
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19641
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.860506
JHH7	CCLE Cell Line Gene Mutation Profiles	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94789
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27558
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42958
PPAR-26484153-CHIP-SEQ-NCI-H1993-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SK-GT-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826084
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00733
Perturb_5795_KO_Stat3_ERP105170	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_5542_KO|KD_Fh1|Foxa2_ERP138019	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.00529
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A81407814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33
aplasia/hypoplasia of the mandible	HPO Gene-Disease Associations	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2872
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23438
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21684
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	1.54467
CHD1-19587682-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU1040	CCLE Cell Line Gene Mutation Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35072
CRCGN012_HEPG2_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02649
delay	GeneRIF Biological Term Annotations	1.0	null
CRX_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19567
Peripheral retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
Retinitis pigmentosa 54	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
NEDD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
SYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16502
Holzgreve-Wagner-Rehder Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
Perturb_13080_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.58024
abnormal cone electrophysiology	MPO Gene-Phenotype Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56293
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
BRD-K11172604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02497
CRCGN013_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13574
retinal rod cell differentiation	GO Biological Process Annotations 2025	1.0	null
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46313713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52533
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893436
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26373
Amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
Perturb_2229_KO_Rela_ERP122918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.42043
CRCGN015_MCF10A_48H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0195
microcephaly	HPO Gene-Disease Associations	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21273
Weight Loss	CTD Gene-Disease Associations	1.0	1.24935
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36202
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
abnormality of the metencephalon	HPO Gene-Disease Associations	1.0	null
Low Vision	DisGeNET Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0222
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11212
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86634
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18123
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0103
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890617
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.819
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64896
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.3595
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59037
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4898
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Perturb_13330_KD_Nfat5_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.37422
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83T-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79302
AARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86946
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.951659
GSE176118_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.966605
ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
abnormality of the macula	HPO Gene-Disease Associations	1.0	null
Perturb_3727_OE_Fut4_SRP242022	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80906
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.49
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
treatment	GeneRIF Biological Term Annotations	1.0	null
BRD-K76833108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40423
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.969
MAP3K14	MSigDB Cancer Gene Co-expression Modules	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.4506
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41945
Bietti crystalline corneoretinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.541
Congenital Absence Of Spleen	DisGeNET Gene-Disease Associations	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52836
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05553
BRD-K74665927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09164
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_1446_KO_Tmem173_SRP221603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.26533
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02873
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947068
retinal diseases	GAD Gene-Disease Associations	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33744
abnormality of hindbrain morphology	HPO Gene-Disease Associations	1.0	null
abnormal retinal outer nuclear layer thickness	MPO Gene-Phenotype Associations	1.0	null
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42054
sclerocornea	HPO Gene-Disease Associations	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20517
BRD-K35964249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13976
Perturb_17_OE_Carhsp1_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.64912
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01197
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.81605
BRD-K17885598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1113
GTEX-XMD3-2326-SM-4AT5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20755
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
Leber congenital amaurosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	1.39713
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18177
testis	HPA Tissue Protein Expression Profiles	1.0	0.858082
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.9997
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89383
Lung	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49584
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EPCAM_OE_GDS4887_343_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Dmbx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.655
HSD17B12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21308
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
SKGT4	DepMap CRISPR Gene Dependency	1.0	2.10857
BRD-K63111122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26744
Joubert syndrome 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44759
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1137
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857616
BRD-K65446780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29268
CILK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8984
Lung adenocarcinoma_LUAD_TCGA-80-5611-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39011
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.923136
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	198.215
FANCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03926
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90911
abnormal anatomic location of the heart	HPO Gene-Disease Associations	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052581
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900868
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366754
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16873
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25817
Leber congenital amaurosis 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.568
Perturb_5042_Mut_Adnp_SRP313259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.99609
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954096
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79327
glaucoma	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78525
canine	GeneRIF Biological Term Annotations	1.0	null
abnormality of color vision	HPO Gene-Disease Associations	1.0	null
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23978
GCT	CCLE Cell Line Gene Mutation Profiles	1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46074
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88864
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73962
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50136
Cohen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
severe	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10574
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.59355
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54889
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.212743
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137144_4_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVCAR-4	GDSC Cell Line Gene Expression Profiles	1.0	1.62015
BRD-K02717912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.94239
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834659
catecholaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422673
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5964-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thin retinal outer nuclear layer	MPO Gene-Phenotype Associations	1.0	null
NPHP4	Pathway Commons Protein-Protein Interactions	1.0	null
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68777
BRD-K32516224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24228
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pericentral	GeneRIF Biological Term Annotations	1.0	null
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
mice	GeneRIF Biological Term Annotations	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17374
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.489
Cystic Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.70775
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74266
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.15795
Hs-578-T	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46094
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893862
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06689
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
Anterior olfactory nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13896
vitro	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33257
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852703
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43543
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80062
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.67141
MEWO	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15287
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34596
C3A	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48817
Perturb_15184_KD_SREBP_SRP190161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.07264
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04591
DB	GDSC Cell Line Gene Expression Profiles	1.0	1.57575
organelle	GO Cellular Component Annotations 2015	1.0	null
Perturb_1267_KD_Prmt7_SRP279352	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.42195
NCIH2170	DepMap CRISPR Gene Dependency	1.0	3.22913
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13312
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.878
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
NCIH2342	CCLE Cell Line Gene Expression Profiles	1.0	1.36713
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.7379
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03691
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6025
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
oligohydramnios	HPO Gene-Disease Associations	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23296
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
abnormality of the pancreas	HPO Gene-Disease Associations	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Leber congenital amaurosis 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.24
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67954
NCI-H441	GDSC Cell Line Gene Expression Profiles	1.0	1.8817
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31898
AM38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73158
GTEX-WH7G-0926-SM-4LVMJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858142
abnormality of the lens	HPO Gene-Disease Associations	1.0	null
Perturb_15615_Mut_Dmd_SRP329695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.48168
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8108-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865347
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07608
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14266
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856919
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371619
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Leiomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17682
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56513
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.56577
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49196
Adventitious root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96824
fabry disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199033
holoprosencephaly	HPO Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847355
Kidney Chromophobe_KICH_TCGA-KN-8429-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18554_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.21892
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66601
eye photoreceptor cell development	GO Biological Process Annotations 2015	1.0	null
Meckel-Gruber Syndrome	DisGeNET Gene-Disease Associations	1.0	null
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.009
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955627
BRD-K38955287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11657
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of long bone morphology	HPO Gene-Disease Associations	1.0	null
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39329
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46353
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10154
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04722
PA-1	GDSC Cell Line Gene Expression Profiles	1.0	2.12578
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13077_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.38966
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.9726
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61941
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21229
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6286
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8971
abnormality of the lower limb	HPO Gene-Disease Associations	1.0	null
BRD-K88802328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28257
Phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2554
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54604
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.988641
non-motile cilium assembly	GO Biological Process Annotations 2023	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	3.04592
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5499
Ca9-22	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84252
GTEX-WYJK-1326-SM-3NB2T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27146
CRCGN009_HEPG2_24H:I08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19725
BRD-K18523456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45397
Ciliopathies	DisGeNET Gene-Disease Associations	1.0	null
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5184
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2177
Perturb_3222_KO_Nhe1_SRP366933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.03705
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
BRD-K79954583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02499
implications	GeneRIF Biological Term Annotations	1.0	null
BRD-K54604127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16468
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42276
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03353
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.815
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13015
Apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.886
PR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50372
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19522
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.55366
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6158
CRCGN012_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2839
IKZF1_01_138	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.88726
Hyalocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
harmalol-5495	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863444
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78731
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.036
Micrognathism	DisGeNET Gene-Disease Associations	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Perturb_12890_KD_Tet1_SRP151818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.49861
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00295
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.398
retinal photoreceptor degeneration	MPO Gene-Phenotype Associations	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040898
KYSE-510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25665
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887221
cone-rod dystrophy 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.803
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0627
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12739
HCC1395	DepMap CRISPR Gene Dependency	1.0	2.19804
GSE62843,GSE64371_2_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52029
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00517
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925361
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56563145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55761
werirb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
Postaxial Foot Polydactyly	DisGeNET Gene-Disease Associations	1.0	null
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55893
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.669
Photophobia	DisGeNET Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NL-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aplasia/hypoplasia of the iris	HPO Gene-Disease Associations	1.0	null
COACH syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.919
TOV21G	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAOV4	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.64589
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91047
GSE151829,GSE151831_1_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2021
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68167
Infertility, Female	CTD Gene-Disease Associations	1.0	1.01587
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842167
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
gamma-tubulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.549
abnormal ocular fundus morphology	MPO Gene-Phenotype Associations	1.0	null
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.53838
Joubert syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.757
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51708
Perturb_13788_KO_Mcph1_SRP233207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58411
Perturb_2164_KD_Chd8_SRP062904	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52273
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89653
retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28087
Retinal Dystrophies	CTD Gene-Disease Associations	1.0	2.88009
TPRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83407
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11045
BRD-K68383485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66173
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
hepatic fibrosis	HPO Gene-Disease Associations	1.0	null
abnormality of the vasculature of the eye	HPO Gene-Disease Associations	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Oculoauricular syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Body mass index (age>50)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	9.7
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838092
Usher syndrome type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
Hereditary spherocytosis type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Arciform density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.20317
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53968
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16591
Perturb_14925_OE_HsATXN3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.72101
Perturb_4682_KO_Mll2_SRP189864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.17499
X-linked juvenile retinoschisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.076
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01388
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18048
strategy	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fissured Tongue	DisGeNET Gene-Disease Associations	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.44166
BRD-K67442425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36918
cilium assembly	GO Biological Process Annotations 2023	1.0	null
JHOC5	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29543
abnormal muscle tone	HPO Gene-Disease Associations	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
aipl1	GeneRIF Biological Term Annotations	1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08971
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.01025
Perturb_14485_OE_Tp73_SRP134969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.03891
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RI1	CCLE Cell Line Gene Expression Profiles	1.0	1.68185
LOUNH91	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42616
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03704
duplication of hand bones	HPO Gene-Disease Associations	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980295
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912163
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC4	CCLE Cell Line Gene Mutation Profiles	1.0	null
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39386
NALOXONAZINE-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35397
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41096
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993163
BRD-K07501326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25941
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838092
emirati	GeneRIF Biological Term Annotations	1.0	null
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52209
multicystic kidney dysplasia	HPO Gene-Disease Associations	1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.591
best	GeneRIF Biological Term Annotations	1.0	null
CAL-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.21501
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Perturb_8512_KO_Bmal1_ERP009958	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.79102
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967579
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
nonmotile primary cilium	GO Cellular Component Annotations 2015	1.0	null
GTEX-PLZ6-1626-SM-3NB23	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832791
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1294
GNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86045
Perturb_4516_Mut_Ep400_SRP081300	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.69143
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.947037
SNU2535	DepMap CRISPR Gene Dependency	1.0	2.81787
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
betamethasone-dipropionate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50923
BRD-K04272258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58142
talipes	HPO Gene-Disease Associations	1.0	null
BRD-K26026745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09252
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH2087	DepMap CRISPR Gene Dependency	1.0	5.7314
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.89256
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3867
HT1197	DepMap CRISPR Gene Dependency	1.0	2.04624
hacat	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36013
angle-closure glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
Kartagener syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09345
night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.282225
BRD-K60517939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40781
abnormality of granulocytes	GWASdb SNP-Phenotype Associations	1.0	0.294564
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7224
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64453
MDA-MB-330	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCCSUP	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05904
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858671
SNU738	DepMap CRISPR Gene Dependency	1.0	2.02188
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08758
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835268
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
k22	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6258
GTEX-RUSQ-0926-SM-47JWU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936992
SNU601	DepMap CRISPR Gene Dependency	1.0	5.9884
BRD-K67817697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06665
MAP3K21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58816
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864467
abnormality of the mandible	HPO Gene-Disease Associations	1.0	null
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.335046
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.84526
hemiplegia/hemiparesis	HPO Gene-Disease Associations	1.0	null
CCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03048
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1129
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34148
Nystagmus, Pathologic	CTD Gene-Disease Associations	1.0	2.88009
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867008
Dissociated Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7888
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CIITA-25753668-RAJI-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	2.57844
amaurosis	GeneRIF Biological Term Annotations	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8611
SNUC5	DepMap CRISPR Gene Dependency	1.0	4.5195
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
COPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26588
understanding	GeneRIF Biological Term Annotations	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_15827_OE_Nrf2_SRP291724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.50226
abnormal electroretinogram waveform feature	MGI Mouse Phenotype Associations 2023	1.0	null
JHUEM7	CCLE Cell Line Gene Mutation Profiles	1.0	null
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868803
retinal rod cell differentiation	GO Biological Process Annotations 2023	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.23191
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71568
BRD-K13225050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41437
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0225
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IB-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV MA15_Day4-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0324
Perturb_13271_KO_Msl2_SRP192624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50606
BRD-K07695007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07236
Perturb_11975_KO_Star_SRP302975	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97109
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07918
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43068
Visual Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
diseases	GeneRIF Biological Term Annotations	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866985
nonmotile primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.50566
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46537
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.845
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20644
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93Y-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15245
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.29453
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981567
Joubert syndrome 24	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.957
BRD-K15863674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61716
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25545
GSE154464_0_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6818
NCIH520	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2273
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Protein of unknown function DUF3250	InterPro Predicted Protein Domain Annotations	1.0	null
abnormal retinal neuronal layer morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_2377_KD_Cdk8_SRP292215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.4251
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.055
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8452
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.796587
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14899
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56674
Rod photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03434
PMC4920181__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57579
Periodic Alternating Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
photoreceptor cell development	GO Biological Process Annotations 2015	1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.01174
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.713
SW837	COSMIC Cell Line Gene Mutation Profiles	1.0	null
poor	GeneRIF Biological Term Annotations	1.0	null
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.4056
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839056
BRD-K40923781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08578
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.435
visual perception	GO Biological Process Annotations 2015	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40303
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28415
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.928857
Root apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.081
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
homozygous	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.83027
BRD-K12555854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52196
Perturb_1016_KO_Nt5e_SRP404924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.86316
GSE151829,GSE151831_1_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.1309
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30855
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.751
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02498
Perturb_5305_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP101434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.08427
BRD-K61978712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00999
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
pigmentosa	GeneRIF Biological Term Annotations	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38593
BRD-K62625902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98618
microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170888
photoreceptors	GeneRIF Biological Term Annotations	1.0	null
SNU1105	Achilles Cell Line Gene Essentiality Profiles	1.0	2.6624
centrosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.39471
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58964
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32493
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35
IL9	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K45860594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09596
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02021
organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13491
cone-rod dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
cell projection	GO Cellular Component Annotations 2015	1.0	null
all	HPO Gene-Disease Associations	1.0	null
renal cyst	HPO Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09317
Retinitis pigmentosa 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
Perturb_17597_KO_Il25_SRP247658	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.13779
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43519
abnormality of the abdominal organs	HPO Gene-Disease Associations	1.0	null
Perturb_5128_KD_Med4_SRP325525	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.29179
CPCN	CCLE Cell Line Gene Mutation Profiles	1.0	null
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15184
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7635
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54733
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01196
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4706
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56459
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09745
Fatigable Positional Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4314
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358546
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12235
Ciliary vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.759
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27881
variants	GeneRIF Biological Term Annotations	1.0	null
Perturb_18558_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.69519
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990424
Polycystic Liver Disease	DisGeNET Gene-Disease Associations	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.5964
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052228
prostanoid receptor binding	GO Molecular Function Annotations 2023	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22595044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45685
Electroretinogram	DisGeNET Gene-Phenotype Associations	1.0	null
SARS-BatSRBD_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.84149
abnormality of prenatal development or birth	HPO Gene-Disease Associations	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05385
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31849
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
GSE160017,GSE160022_1_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Non-Fatigable Positional Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-3.83493
BRD-K14431723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3294
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.572
NCIH82	CCLE Cell Line Gene Expression Profiles	1.0	2.40744
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06453
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A898-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.53606
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053292
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.914788
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44103
decreased b-wave amplitude	MGI Mouse Phenotype Associations 2023	1.0	null
cilium assembly	GO Biological Process Annotations 2025	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.434
Ciliopathies	WikiPathways Pathways 2024	1.0	null
Nephronophthisis 19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_24hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16611_KO_Np95_SRP311865	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40936
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nystagmus	HPO Gene-Disease Associations	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33381
preoptic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01704
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59365
EZH2	ENCODE Transcription Factor Targets	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12284
Nephronophthisis 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06295
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Perturb_3101_KO_Mid2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.77622
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23831
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33447
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	1.0	1.57682
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.791495
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39306
abnormal sensory neuron morphology	MPO Gene-Phenotype Associations	1.0	null
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.068
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39636
SLC16A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51562
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43774
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63481
Pseudopapilledema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75905
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.83476
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895795
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.166
Retinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
Perturb_4811_KO_Mapk1_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84589
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40238
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65086352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89267
NOP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5078
LCAT	MSigDB Cancer Gene Co-expression Modules	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03769
keratoconus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215992
keratoconus	HPO Gene-Disease Associations	1.0	null
abnormal neutrophil cell number	GWASdb SNP-Phenotype Associations	1.0	0.592045
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6822
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851666
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963036
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53967
primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.29166
thromboxane A2 receptor binding	GO Molecular Function Annotations 2023	1.0	null
Scotoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.014
VCB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
retina spots	MGI Mouse Phenotype Associations 2023	1.0	null
DPCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88457
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05914
LNCAPCLONEFGC	CCLE Cell Line Gene Mutation Profiles	1.0	null
lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060982
A-CA-04-2009(H1N1)_7Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.18742
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.991061
all	GWASdb SNP-Phenotype Associations	1.0	0.032179
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMM1	CCLE Cell Line Gene Expression Profiles	1.0	2.04681
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71868
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52517
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
BRD-K22471908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63154
CHRNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12726
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82639
Perturb_13989_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.3646
Cleft Palate	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05021
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60448
Perturb_5206_KO_Dgcr8_SRP137729	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.22119
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93937
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932115
Macular retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
photoreceptor connecting cilium	GO Cellular Component Annotations 2015	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00984
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05369
ADAMTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01037
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
full cheeks	HPO Gene-Disease Associations	1.0	null
highlight	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984273
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GM133	BioGPS Cell Line Gene Expression Profiles	1.0	1.20701
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30279
duplication involving bones of the feet	HPO Gene-Disease Associations	1.0	null
foot polydactyly	HPO Gene-Disease Associations	1.0	null
axoneme	GO Cellular Component Annotations 2015	1.0	null
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858178
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052809
CW2	CCLE Cell Line Gene Mutation Profiles	1.0	null
Meckel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44935
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58964
FRK	MSigDB Cancer Gene Co-expression Modules	1.0	null
abnormal electroretinogram	HPO Gene-Disease Associations	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11204
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38042
SARS-CoV_48Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88659
intermediate stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10603
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927823
outer	GeneRIF Biological Term Annotations	1.0	null
BRD-K43159427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89719
PMC4823079-oncotarget-07-2889-s002.xls-Feuil1-Supplementary_table_1_AEU_events_shared_by_DEK_and_WT1-expressing_cells_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
TEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03614
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.406798
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21716
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001527
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58797
BRD-K20028734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32664
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.42128
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17939
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948494
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8979
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
Perturb_14915_KD_Mof_SRP060636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.3716
retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.75641
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
family	GeneRIF Biological Term Annotations	1.0	null
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0617
network	GeneRIF Biological Term Annotations	1.0	null
ciliadependent	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Leber congenital amaurosis 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.279
GSE122711_1_v_0_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
due	GeneRIF Biological Term Annotations	1.0	null
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08395
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956388
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.858
Multidirectional Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IQCE	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32269
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.0363
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62368
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865479
ractopamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49883
Leber congenital amaurosis 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.646
Root tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.779
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67782
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.1036
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21924
strictly	GeneRIF Biological Term Annotations	1.0	null
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central	GeneRIF Biological Term Annotations	1.0	null
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0854
abnormality of the foot	HPO Gene-Disease Associations	1.0	null
ciliary part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.002908
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886424
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
TSPAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45958
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
Hereditary spherocytosis type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Perturb_1690_KD_Kdm4c_ERP009549	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.51542
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33507
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OAW42	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32107
sensory perception of light stimulus	GO Biological Process Annotations 2015	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46074
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02835
Perturb_5126_KD_Med30_SRP325525	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.8082
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838577
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33698
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01149
retina photoreceptor degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
documented	GeneRIF Biological Term Annotations	1.0	null
GSE111035,GSE111040_8_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02772
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39844
SNUC5	CCLE Cell Line Gene Mutation Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.38011
Leber congenital amaurosis 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.543
Perturb_12336_KD_BRD4_SRP219026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.88269
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049173
Perturb_9544_KO_Ucp1_SRP187003	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.91769
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0686
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54674
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945272
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36123
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21336
layer 1 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31111
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83346
BRD-K60653414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49685
Renal medulla cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.161
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05005
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen	GTEx Tissue Gene Expression Profiles	1.0	1.58091
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO704	CCLE Cell Line Gene Expression Profiles	1.0	1.65584
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K83013052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4532
Perturb_5695_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.26754
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16684
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9415
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5102
Genetic Diseases, X-Linked	HuGE Navigator Gene-Phenotype Associations	1.0	null
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27306
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04336022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8287
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23L-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duplication of phalanx of hand	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46434
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.81634
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894398
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.943
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7999
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.607319
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06906
RPLP0	Hub Proteins Protein-Protein Interactions	1.0	null
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
15860665-Table1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_5112_KD_Med10_SRP325525	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	1.60112
furrowed tongue	HPO Gene-Disease Associations	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.8512
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21525
Perturb_1681_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.12326
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051741
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994335
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2295
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4562
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27531
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.199
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20802
abnormality of the liver	HPO Gene-Disease Associations	1.0	null
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23966
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852999
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.902786
aplasia/hypoplasia involving bones of the skull	HPO Gene-Disease Associations	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15392
PMC11257629-media-9.xls-METTL3_KD_upregulated_Genes-METTL3KD_UPregulated_Genes_1694_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24207
JM1	CCLE Cell Line Gene Expression Profiles	1.0	1.76205
Perturb_17440_Mut_Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.74769
abnormal vitreous body morphology	MPO Gene-Phenotype Associations	1.0	null
MTFMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13955
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
Respiratory Tract Infections	CTD Gene-Disease Associations	1.0	1.05015
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30578
Congenital Amaurosis Of Retinal Origin	DisGeNET Gene-Disease Associations	1.0	null
NCIH2291	CCLE Cell Line Gene Mutation Profiles	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12235
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17701
BRD-K66641352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05094
NP5	DepMap CRISPR Gene Dependency	1.0	4.32901
RETREG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51505
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Jalili syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921283
abnormal retinal pigmentation	HPO Gene-Disease Associations	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K50058129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20354
BRD-A28219573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01855
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21747
Vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.091
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01432
HCC1395	CCLE Cell Line Gene Mutation Profiles	1.0	null
Perturb_14924_KO_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.76447
BRD-K81120201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43616
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17058
UACC-893	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K69668461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33081
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	2.07484
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11081
CMLT1	CCLE Cell Line Gene Mutation Profiles	1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
Alstrom syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.754
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.59
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4337
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.7719
cryptorchidism	HPO Gene-Disease Associations	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947068
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
SNU8	CCLE Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881442
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00457
PLOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26536
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.41917
GSE120595_0_v_1_arid2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07929
leukopenia	GWASdb SNP-Disease Associations	1.0	0.373929
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
CRCGN010_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45012
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
COLO201	CCLE Cell Line Gene Mutation Profiles	1.0	null
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67092
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53898
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01971
GTEX-S4UY-0726-SM-4AD6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974338
BRD-K62152527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1098
EWSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
ChIP_TIP60_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29645
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Leber congenital amaurosis 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.49174
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.67638
BRD-K68298468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24759
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.41
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09114
BRD-K18211442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04063
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1388
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemiplegia	DisGeNET Gene-Disease Associations	1.0	null
Perturb_13071_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.63817
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826529
Low Tension Glaucoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2872
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of toe	HPO Gene-Disease Associations	1.0	null
DMS-79	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K69408624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06931
Carpenter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85696
TOV-21G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	1.2085
vision	GAD High Level Gene-Disease Associations	1.0	0.293278
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_2876_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cone-rod dystrophy 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
AN3CA	CCLE Cell Line Gene Mutation Profiles	1.0	null
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
GSE196117_6_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0333
Nephronophthisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
colocalized	GeneRIF Biological Term Annotations	1.0	null
SU-DHL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.51726
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHOM1	CCLE Cell Line Gene CNV Profiles	1.0	1.79036
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10739
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910929
abnormal rod electrophysiology	MPO Gene-Phenotype Associations	1.0	null
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01301
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23345
Physical disorder	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39875
BRD-K70923850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50482
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890616
Nonpigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33527
Perturb_10988_KO_Gnpda2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.60176
posterior (caudal) superior temporal cortex (area 22c)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07763
CRO-AP2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52758
chorioretinal abnormality	HPO Gene-Disease Associations	1.0	null
BRD-K65598127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16548
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901121
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26011
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62707
MED13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46571
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941409
Perturb_1263_KO_Mll3_SRP352738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.73643
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
retina development in camera-type eye	GO Biological Process Annotations 2015	1.0	null
abnormality of the fourth ventricle	HPO Gene-Disease Associations	1.0	null
they	GeneRIF Biological Term Annotations	1.0	null
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
Rectum adenocarcinoma_READ_TCGA-G5-6233-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.30067
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
rod	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1809
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00146
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03199
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46551
Perturb_13255_KD_Paf1_SRP083772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.551425
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
Perturb_11228_KO_Srf_SRP050501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64716
GSE110178_4_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.35211
Leber Congenital Amaurosis	CTD Gene-Disease Associations	1.0	2.88009
Perturb_17415_OE_Gata3_SRP150425	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.08998
hand polydactyly	HPO Gene-Disease Associations	1.0	null
Perturb_13212_KO_Lima1_ERP128082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.54764
Distal portion of axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.459
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7322
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9574
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950614
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.8997
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48761
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04207
eye disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15803
BRD-K71521842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71687
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83617
Aland Island eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.49182
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
COQ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31537
Lung adenocarcinoma_LUAD_TCGA-50-8457-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881072
Rind	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
L428	DepMap CRISPR Gene Dependency	1.0	3.04556
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21526
BRD-K27320944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84055
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990156
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6223-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985683
protein binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_14920_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.91375
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28134
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.982545
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.718125
nonmotile primary cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
abnormality of the posterior segment of the eye	HPO Gene-Disease Associations	1.0	null
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72946
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17619
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12892
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06468
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51131
tissue development	GO Biological Process Annotations 2015	1.0	null
Perturb_4940_KO_Cbfa2t2_SRP061948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.81914
Gyrate atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.569
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07825
agranulocytosis	GWASdb SNP-Disease Associations	1.0	0.690343
degeneration	GeneRIF Biological Term Annotations	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5046
BRD-K40494117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18927
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62171
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.846
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850138
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.49182
Perturb_1614_KO_Prkcd_SRP386893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.27759
HIPK2_defectivemutant_29_GDS4233	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.58452
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75669
Perturb_12013_KO_B2_Mm2_SRP374407	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.7329
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39428
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10552
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857378
Leber congenital amaurosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.827
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
Root quiescent center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
primary cilium	GO Cellular Component Annotations 2015	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52157
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.9579
COLO205	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_macaque_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Body mass index x sex x age interaction (4df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11212
Abnormal Color Vision	DisGeNET Gene-Phenotype Associations	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16338
most	GeneRIF Biological Term Annotations	1.0	null
GSE217685_0_v_1_ddx20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HRT18	CCLE Cell Line Gene Mutation Profiles	1.0	null
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.479
BRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25229
PMC12756533-mmc1.pdf-8-FOXO3_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.478
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48365
GSE126777_3_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4R-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the lymphatic system	HPO Gene-Disease Associations	1.0	null
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74824
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824085
retrosplenial cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32051
Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85352
BRD-K75821161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50069
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900368
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72877
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7D0-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996208
low-set ears	HPO Gene-Disease Associations	1.0	null
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24542
GSE190235_3_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966221
Periciliary membrane compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
BRD-K30566330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99934
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9357
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48806
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82731
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31267
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K23598860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85632
spleen_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.00194
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952165
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.92314
BRD-K83815133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49185
X-linked atrophic macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30121969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22879
Perturb_7101_KO_Irs1_SRP201874	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.19985
Aplasia/Hypoplasia Of The Cerebellar Vermis	DisGeNET Gene-Phenotype Associations	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.51386
Perturb_12606_KO_Lin28a/Lin28b_SRP300815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
Rhabdomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68651
BRD-K93900188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11055
GSE104022_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74103290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01474
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46739
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
chr14_21308432_G_A_b38	GTEx eQTL 2025	1.0	1.95108
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25374
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12516
BRD-K95951626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28002
Unilateral retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04139
MAPK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49047
lateral preoptic nucleus, PO2 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10536
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.891308
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.82272
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29059
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31423
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03407
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23604
Prostate adenocarcinoma_PRAD_TCGA-HC-8261-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15752_KO_Ezh2_SRP096837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19945
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.7311
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35627
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.76596
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5523
BRD-K74382273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22382
Leber congenital amaurosis 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.813
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2458
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.615
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44132
Perturb_5104_KO_Ythdc1/Dux_SRP251747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.50525
EW8	DepMap CRISPR Gene Dependency	1.0	2.61348
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.715
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11537
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10431
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54276
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.74903
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67767
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12154
IGF1R_druginhibition_47_GSE14024	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.06962
Vitelliform macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40029
retina	GeneRIF Biological Term Annotations	1.0	null
ciliary cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.829089
PMC8020666-pnas.2015855118.sd05.xlsx-LPS_4_ape-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62783
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21814
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040887
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCND1	ChEA Transcription Factor Targets	1.0	null
depressed nasal ridge	HPO Gene-Disease Associations	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.657
EXOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12998
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37829
BRD-K63859730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00497
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8203
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03545
CRCGN013_HEPG2_24H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05194
Perturb_1942_KO_Nelfb_SRP132312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.88896
Perturb_5183_KD_Ssrp1_SRP094584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16381
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
NCI-H1048	GDSC Cell Line Gene Expression Profiles	1.0	1.4982
Perturb_9742_KO_Fxr_SRP241086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.10318
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904005
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	1.52001
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6418
some	GeneRIF Biological Term Annotations	1.0	null
retina degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
NCIH1435	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28378
absent photoreceptor outer segment	MPO Gene-Phenotype Associations	1.0	null
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
sf-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.246124
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61124142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02117
GTEX-XXEK-1826-SM-4BRVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834845
Photoreceptor connecting cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.995053
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05919
PL4	DepMap CRISPR Gene Dependency	1.0	2.04114
COMMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55875
Taproot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5675
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of skull size	HPO Gene-Disease Associations	1.0	null
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rpgrip1	GeneRIF Biological Term Annotations	1.0	null
mdamb415	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936247
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17503
Perturb_13507_KD_Rnaseh2c_SRP197098	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.49081
Double Ureter	DisGeNET Gene-Disease Associations	1.0	null
vitreal fibroplasia	MPO Gene-Phenotype Associations	1.0	null
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.93359
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843611
DMS79	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-NB4-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_NB4_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
EID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75348
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8085
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72884
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64488
Perturb_6163_KO_Sh3gl1_SRP315284	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.88961
SRP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41333
A172	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28768
Glaucoma, Open-Angle	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21253
IMR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57946
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.488
CRCGN016_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87022
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.456449
Perturb_5307_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP101434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.30978
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054342
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.51386
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16712_KO_Ppbp_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.4674
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.954941
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.399363
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4192
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.69951
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2218	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834373
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880735
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62447
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941418
OCI-AML3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70176
CRCGN015_MCF10A.TP53.M_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20915
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94305
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11835
Perturb_1657_KO_Prkcd_SRP386893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.63529
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904616
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93511
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13696
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.299
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of the skull base	HPO Gene-Disease Associations	1.0	null
micrognathia	HPO Gene-Disease Associations	1.0	null
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2463
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14443
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3576
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16433
Retinoid acid signaling-responsive fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
16611997-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
LEUTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04965
LB2518-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MM1S	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50953
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.796587
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10099
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2651
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superficial layers of olfactory entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06098
abnormal eye electrophysiology	MPO Gene-Phenotype Associations	1.0	null
Neuronal ceroid lipofuscinosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
Lung transplant rejection_Trachea_GSE3418	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.07401
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.882474
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01251
Perturb_13256_KD_Phf5a_SRP083772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16049
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76905
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47332
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846884
MS (Multiple Sclerosis)_B Cell Lymphocyte_GSE10064	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53437
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49C-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.174424
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A7r5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
HEC251	CCLE Cell Line Gene Mutation Profiles	1.0	null
interacts	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.78488
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.2146
NO11	DepMap CRISPR Gene Dependency	1.0	10.1637
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5176
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976098
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91502
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0589
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.95709
BZW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62848
MZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02844
NCI-H1395	GDSC Cell Line Gene Expression Profiles	1.0	1.8742
T3M3	DepMap CRISPR Gene Dependency	1.0	3.29951
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.191
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0688
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67881
Cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
pancreatic fibrosis	HPO Gene-Disease Associations	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38175
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06468
cone-rod dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.06
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21364
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32912
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925325
bardet-biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.606543
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
aplasia/hypoplasia of the cerebrum	HPO Gene-Disease Associations	1.0	null
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06315
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24004
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.05136
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919505
Microcornea	DisGeNET Gene-Disease Associations	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16695
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6497090-tvst-08-02-12_s02.xlsx-FINAL-AD-AR-XL-ONE-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MKN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.4746
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.87653
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38899
RB1_KD_GSE50532_660_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1792	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42478
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31676
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.998927
NCIH1781	CCLE Cell Line Gene CNV Profiles	1.0	1.40082
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.968121
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01794
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895545
PL21	CCLE Cell Line Gene Mutation Profiles	1.0	null
GSE73381,GSE73382_0_v_1_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18588
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41404
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3455
mode of inheritance	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901719
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00735
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
NUTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23342
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29906
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
abnormal cone electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Abnormality of the eye	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE202284,GSE202289_1_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.982909
GSE129244_0_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36309
YD38	CCLE Cell Line Gene Mutation Profiles	1.0	null
corneal opacity	HPO Gene-Disease Associations	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.34645
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6916
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00669
Keratoconus	DisGeNET Gene-Disease Associations	1.0	null
Pericentriolar material	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.259
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0562
Perturb_4446_KD_Fbl_DRP007972	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.23353
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
abnormality of the posterior cranial fossa	HPO Gene-Disease Associations	1.0	null
vitreal fibroplasia	MGI Mouse Phenotype Associations 2023	1.0	null
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Perturb_12694_KO_p75_SRP327861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50566
neutropenia	GWASdb SNP-Phenotype Associations	1.0	0.592045
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH441	CCLE Cell Line Gene Expression Profiles	1.0	1.84635
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.966
ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.42082
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392686
Perturb_13761_KO_Hotair_SRP026100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.60431
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.337072
short photoreceptor inner segment	MPO Gene-Phenotype Associations	1.0	null
BRD-K87743988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.067
SNU-423	COSMIC Cell Line Gene Mutation Profiles	1.0	null
peripheral	GeneRIF Biological Term Annotations	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850897
Abnormality Of The Eye	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_16651_KD_Fus_SRP179634	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.5714
TE9	DepMap CRISPR Gene Dependency	1.0	2.22899
Perturb_3379_KO_Pgd_SRP309436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988316
Perturb_14921_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.00887
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35565
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7549
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.95996
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862675
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26492
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6506
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11212
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
aplasia/hypoplasia involving the skeleton	HPO Gene-Disease Associations	1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19415
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
Perturb_5540_KO_Fh1_ERP138019	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.89603
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6047740__F6	PFOCR Pathway Figure Associations 2023	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84953
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0506
intracranial cystic lesion	HPO Gene-Disease Associations	1.0	null
Perturb_13122_OE_MYC/Kras_ERP109041	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34134
BRD-K78612514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2693
GTEX-S341-1526-SM-4AD6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902282
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93185
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12221
EMILIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36449
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.078504
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
pancreatic cysts	HPO Gene-Disease Associations	1.0	null
sign	GeneRIF Biological Term Annotations	1.0	null
retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316951
Morgagni cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
HGC27	CCLE Cell Line Gene Mutation Profiles	1.0	null
Cystoid macular edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7416
cell-cell adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.328708
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.339
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8687
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882696
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52908
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30423
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.103716
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1683_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.5739
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87709
BRD-K33891642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46989
Multicystic Dysplastic Kidney	DisGeNET Gene-Disease Associations	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82937
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8462
Perturb_13152_KO_Yme1l_SRP293109	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.13409
PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67695
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
Leber hereditary optic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
CRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29215
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24812
BRD-U07653185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26193
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54862
abnormality of the retinal vasculature	HPO Gene-Disease Associations	1.0	null
AP1S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88305
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23438
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
SU-DHL-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146074_10_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997732
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57886
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.702928
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910808
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
SMAD1	ChEA Transcription Factor Targets	1.0	null
bewo	HPA Cell Line Gene Expression Profiles	1.0	0.957676
Retinitis pigmentosa 55	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02945
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35338
abnormality of the tongue	HPO Gene-Disease Associations	1.0	null
Perturb_4806_KO_Stat5b_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.98685
TUHR4TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71339
Perturb_13240_KO_Lamtor1_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.88681
aplasia/hypoplasia affecting the eye	HPO Gene-Disease Associations	1.0	null
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07778
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.7866
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51843685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43445
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24741
Joubert syndrome 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
SAP30	ENCODE Transcription Factor Targets	1.0	null
BRD-K12710356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32004
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12699
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15472
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.874944
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.023
Septum pellucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05559
BRD-K09767767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26475
BRD-K40221630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02012
Seizures	DisGeNET Gene-Phenotype Associations	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.34984
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72945
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.49182
photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.943059
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886215
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47392
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52656
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
NCI-H520	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.537
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88258
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.05972
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.843956
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1307
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42348
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52368
BRD-K11826883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18663
KMS28BM	CCLE Cell Line Gene Mutation Profiles	1.0	null
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.228
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41335
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989656
Bmi1_Deficiency_GDS4816_323_mouse_Primary lung cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91897
assembly	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29427
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.882
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34148
NCIH2023	CCLE Cell Line Gene Mutation Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.832
BRD-A89575866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40406
FOXP2	ChEA Transcription Factor Targets	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95839
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6693
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45372
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36606
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052365
NCIH23	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.21078
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68344
HCC2218	COSMIC Cell Line Gene Mutation Profiles	1.0	null
prepontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21734
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893088
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25028
intermediate stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1366
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08509
TOV112D	CCLE Cell Line Gene CNV Profiles	1.0	2.16068
BRD-K69543414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43222
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9738
Perturb_4709_KO_Hesx1_ERP023509	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13422
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.111969
seizures	HPO Gene-Disease Associations	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1999
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45943
ZMYND11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25011
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050596
Perturb_13265_KO_chr3_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.997
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0168
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
widened posterior fossa	HPO Gene-Disease Associations	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4754
cone-rod dystrophy 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.171
NCIH2066	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53395
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81959
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20973
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50382
BRD-K20284960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04241
Iminoglycinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17568
Electrocardiogram morphology (amplitude at temporal datapoints)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.33957
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
abnormality of the cerebral subcortex	HPO Gene-Disease Associations	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1648
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841668
Neuronal ceroid lipofuscinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.84908
usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.595233
report	GeneRIF Biological Term Annotations	1.0	null
Perturb_15674_KD_Hnrnpu_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86863
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.33415
RCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45623
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
MZT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48517
Perturb_17311_KO_Rhox10_SRP302924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.6098
NCIH1568	CCLE Cell Line Gene Mutation Profiles	1.0	null
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584422
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.42321
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cone-rod dystrophy 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09725
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993881
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vertical Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
abnormality of the uvea	HPO Gene-Disease Associations	1.0	null
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.80463
BRD-A78125048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87977
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Ciliary transition zone	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
abnormality of refraction	HPO Gene-Disease Associations	1.0	null
BRD-K89121101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03737
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23301
PTPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09767
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19517
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04787
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
TN2	DepMap CRISPR Gene Dependency	1.0	2.21361
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91573
Eye cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
retinal rod cell development	GO Biological Process Annotations 2023	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08837
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32912
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4QS-0326-SM-2I3EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33094
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85159
Perturb_6746_KO|KD_UPF3B|UPF3A_SRP327782	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33093
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24883
cerebellar malformation	HPO Gene-Disease Associations	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.40288
TP53	ChEA Transcription Factor Targets	1.0	null
UBE2N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1854
Accessory Spleen	DisGeNET Gene-Disease Associations	1.0	null
NB69	DepMap CRISPR Gene Dependency	1.0	2.2898
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal leukocyte count	GWASdb SNP-Phenotype Associations	1.0	0.378764
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.883
neutropenia	GWASdb SNP-Disease Associations	1.0	0.690343
late-onset retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40667
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055843
Ellis-Van Creveld syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
duplication of bones involving the upper extremities	HPO Gene-Disease Associations	1.0	null
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
Perturb_4767_KO_Kap1_SRP065215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.20528
Retinal telangiectasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
Ciliary transition fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.291
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49545
peripheral blood mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.164352
Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0141
visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330094
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16219
cingulate gyrus, parietal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.967229
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07925
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03592
Leber Congenital Amaurosis	DisGeNET Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888509
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.887981
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.796587
Dandy-Walker Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Dentate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90746
rpgrip	GeneRIF Biological Term Annotations	1.0	null
L363	Achilles Cell Line Gene Essentiality Profiles	1.0	1.49492
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-3.35802
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824882
Cone-Rod Dystrophy 13	CTD Gene-Disease Associations	1.0	2.88009
Glaucoma	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.375
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6878
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043981
BRD-K18562194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01145
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03751
DDT1-MF-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.895082
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058034
Galactose epimerase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53334
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886215
Cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25622
Perturb_5251_KO_Klf2_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Plant crown	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.12
Leber congenital amaurosis 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18524
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QT-1526-SM-3NMCT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19751
BRD-K49313348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32616
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861682
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testosterone_mus musculus_gpl1261_gse17553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.943265
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.47308
Retinoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859685
Temporary Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360036
BRD-K84775364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08267
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30559
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4381
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.38954
Autosomal dominant vitreoretinochoroidopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
spleen	HPA Tissue Gene Expression Profiles	1.0	1.66748
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal retinal photoreceptor morphology	MPO Gene-Phenotype Associations	1.0	null
neurodevelopmental	GeneRIF Biological Term Annotations	1.0	null
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.681
Perturb_5288_KD_Rpl10a_SRP064202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.51608
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968994
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995899
GTEX-Q2AH-1026-SM-48TZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02232
Perturb_5026_KO_4930500J02Rik_SRP072189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.62584
CHAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84205
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29649
KYSE70	CCLE Cell Line Gene Mutation Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4509
Perturb_3097_KO_Lama4_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.46289
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hTERT-RPE1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37365
BRD-K81956993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03426
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32241
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K08142337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38504
Lateral root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.777
Acute Myeloid Leukemia_LAML_TCGA-AB-2981-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09065
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24655
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00033
abnormal location of ears	HPO Gene-Disease Associations	1.0	null
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1509
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.51386
non-motile cilium assembly	GO Biological Process Annotations 2025	1.0	null
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.167
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.084902
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YX-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.08968
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.301
locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.562042
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897534
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
16964388-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-PW2O-0126-SM-48TC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844773
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22794
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
decreased corneal thickness	HPO Gene-Disease Associations	1.0	null
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56187
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19317
Aplasia/Hypoplasia Of The Iris	DisGeNET Gene-Disease Associations	1.0	null
absent rod-and cone-mediated responses on erg	HPO Gene-Disease Associations	1.0	null
Retinitis pigmentosa 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.134
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252261
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81378
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72322
throughout	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66X-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.64552
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23627
NCI-H524	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KU1919	DepMap CRISPR Gene Dependency	1.0	4.44622
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
photoreceptor	GeneRIF Biological Term Annotations	1.0	null
bae1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
GSE146074_6_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984273
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14623
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.895552
BRD-K29128208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16802
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07675
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027071
Congenital stationary night blindness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900957
abnormal eye morphology	MPO Gene-Phenotype Associations	1.0	null
Acquired night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.943163
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00563
hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.274021
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5383
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Low-Set, Posteriorly Rotated Ears	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_4713_KO_Hnrnpu_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.51328
DU145	DepMap CRISPR Gene Dependency	1.0	4.44077
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8014
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22304
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4758
Perturb_15116_KD_Rtn4_SRP278924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20607
SW1116	GDSC Cell Line Gene Expression Profiles	1.0	1.56582
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069651
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1447
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948673
Lung adenocarcinoma_LUAD_TCGA-L4-A4E5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04911
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26196
Retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04041
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.20787
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46098
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24401
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4798-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
nek4	GeneRIF Biological Term Annotations	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13011
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859733
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
congenital hepatic fibrosis	HPO Gene-Disease Associations	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.44052
retinopathies	GeneRIF Biological Term Annotations	1.0	null
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
BRD-K94011376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24889
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13843_KD_Fgfr1_SRP371980	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.70993
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30812
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
crosstalk	GeneRIF Biological Term Annotations	1.0	null
leukopenia	GWASdb SNP-Phenotype Associations	1.0	0.592045
BRD-K70558234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49526
BRD-K28455914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66685
GSE133927_1_v_0_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cephalocele	HPO Gene-Disease Associations	1.0	null
BRD-K86838462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31317
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.00098
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82735
Perturb_1917_KO_Arhgef2_SRP186268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.14846
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
wm115	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
NCI-H2135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04135
LU-65	GDSC Cell Line Gene Expression Profiles	1.0	1.82995
SKNEP1	DepMap CRISPR Gene Dependency	1.0	2.21273
Perturb_16713_KO_Prkab1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.9747
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0481
LOUNH91	DepMap CRISPR Gene Dependency	1.0	2.35031
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30638
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26301
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6808
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29732
ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.932658
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846951
LY-294002-328	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K78015598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12297
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13276
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35833
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35863275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20369
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48916
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59363
BRD-K82379643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20025
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0009
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03418
BRD-K73769678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34462
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965121
HCC2935	CCLE Cell Line Gene Expression Profiles	1.0	1.46794
GSE217201_1_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
rMC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
NZM3	DepMap CRISPR Gene Dependency	1.0	2.41531
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124516
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.945
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479702
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.351
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85696
ZNF823	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08804
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81461
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36425
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
Urethral Atresia	DisGeNET Gene-Disease Associations	1.0	null
abnormal photoreceptor outer segment morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Depressed Nasal Ridge	DisGeNET Gene-Phenotype Associations	1.0	null
isoforms	GeneRIF Biological Term Annotations	1.0	null
Perturb_12127_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
far	GeneRIF Biological Term Annotations	1.0	null
low tension glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.429266
levonorgestrel-3606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12468
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46855
Leber congenital amaurosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.524
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.83352
BRD-K10055064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79045
Perturb_10360_KO_Arid5a_SRP288358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.86467
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947068
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957094
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23022
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998831
WNT1	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Cone matrix sheath	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.555
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.741
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.87276
SKMEL30	CCLE Cell Line Gene Mutation Profiles	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
BRD-K71755682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50881
Root hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.853
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05791
Perturb_12062_KO|KO_Stat5a|Stat5b_SRP012574	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_11153_KO_Kap1_SRP065215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.9264
Perturb_4488_KO_Rnu11_SRP309496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.71036
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07021
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_2145_KO_Mertk_SRP377624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35509
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73939
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.733
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00866
life	GeneRIF Biological Term Annotations	1.0	null
retinitis	GeneRIF Biological Term Annotations	1.0	null
Esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12235
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8429
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.47755
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050565
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10336
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1486
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
661W cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11752
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.792
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984273
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80452
abnormality of the amniotic fluid	HPO Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02912
glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.111745
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68268
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06192
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29925
TOV-112D	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
cerebellar nuclei of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15816
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86972
NUDT15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91859
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888978
postaxial polydactyly	HPO Gene-Disease Associations	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11617
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26809097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04677
seckel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.522273
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07784
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.35904
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.969746
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.962775
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.3638
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97918
ventriculomegaly	HPO Gene-Disease Associations	1.0	null
foci	GeneRIF Biological Term Annotations	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23438
Simpson-Golabi-Behmel syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
BRD-K22475995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0446
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.589
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0759
GSE146074_9_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Oculocutaneous albinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28111
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.03325
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11969
Perturb_6383_KO_Mettl14_SRP344542	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.43003
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3687
cilium	GO Cellular Component Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23373
Perturb_9415_KD_Mecom_SRP356893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.59678
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.888512
abnormal retinal outer nuclear layer morphology	MPO Gene-Phenotype Associations	1.0	null
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28346
BRD-K87815532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15237
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33848
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924484
abnormality of the optic disc	HPO Gene-Disease Associations	1.0	null
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.436
Perturb_4962_KO_Dot1l_SRP214101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.66124
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.528
GSE110178_2_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41771
eye photoreceptor cell development	GO Biological Process Annotations 2023	1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23753
BRD-K36697652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18746
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
HS571T	CCLE Cell Line Gene CNV Profiles	1.0	2.38207
Orofaciodigital syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.892
postaxial hand polydactyly	HPO Gene-Disease Associations	1.0	null
Hyperopia	DisGeNET Gene-Phenotype Associations	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29344
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02399
HNF4, COUP	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_13231_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
literature	GeneRIF Biological Term Annotations	1.0	null
aplasia/hypoplasia of the corpus callosum	HPO Gene-Disease Associations	1.0	null
BRD-K41690760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0165
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.519
SK-NEP-1	GDSC Cell Line Gene Expression Profiles	1.0	1.51081
Perturb_13267_KO_chr2_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.8902
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13985
COPD - Chronic obstructive pulmonary disease_Bronchial epithelium_GSE3320	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.34027
CRCGN016_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00925
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.764
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
forms	GeneRIF Biological Term Annotations	1.0	null
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.987834
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44351
HCC366	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7673
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3126
Bradyopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT474	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.67467
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
Perturb_3007_KD_Satb1_SRP068358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.00179
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3081_KO_Dock11_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.69436
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06341
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21164
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.475423
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14436
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01119
Nephronophthisis	DisGeNET Gene-Disease Associations	1.0	null
PMC11665559-jciinsight-9-183889-s131.xlsx-Fig2DiffBind_MYB_TR-PLEvsNTC-WT-Gene_Name_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63391
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58283
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911923
Polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.309
BNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4093
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10805
Perturb_1679_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.14823
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.198
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
retinal	GeneRIF Biological Term Annotations	1.0	null
Perturb_3481_KO_Ccn1_SRP304010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.93733
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1176
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2617
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2555
abnormality of finger	HPO Gene-Disease Associations	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058125
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
KMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32389
BRD-K75130046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10208
abnormality of vision	HPO Gene-Disease Associations	1.0	null
Hedgehog signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	3.12388
abnormality of the cerebral ventricles	HPO Gene-Disease Associations	1.0	null
Leber congenital amaurosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1231
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878696
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2673
POU5F1	ChEA Transcription Factor Targets	1.0	null
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
GSE171837_0_v_3_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.71205
GTEX-RWS6-0726-SM-47JXI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04698
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85696
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0566
GSE250518_0_v_2_trpm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17442_OE|Mut_Tal1|Akt_SRP366791	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.1219
situs inversus totalis	HPO Gene-Disease Associations	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22146
Muscle Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K77987907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12027
BSG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49871
Perturb_16_KO_Mga_SRP314000	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64037
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6839
FKBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59126
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895143
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48615
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_5061_KD_Cnot10_SRP251834	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.668
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03801
BRD-K13122423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36457
Perturb_15115_KD_Rtn4_SRP278924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.21745
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2313287	CCLE Cell Line Gene Mutation Profiles	1.0	null
aplasia/hypoplasia affecting the uvea	HPO Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1702
UBLC1	CCLE Cell Line Gene Mutation Profiles	1.0	null
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07412
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87413
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68475
BRD-K50066702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12851
ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.776384
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22063
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958509
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08871
inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358174
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912163
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85763
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04129
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01882
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82866
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K55196996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87264
Oligohydramnios	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K18334106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36087
KAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02651
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62989
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.645287
amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.958585
BRD-K41726296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02839
OCIAML3	CCLE Cell Line Gene Mutation Profiles	1.0	null
nephrocystin4	GeneRIF Biological Term Annotations	1.0	null
BRD-K23091373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30212
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16893
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49456
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
Malformations Of Cortical Development	DisGeNET Gene-Disease Associations	1.0	null
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACADM_KO_GDS4546_512_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37122
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13783
abnormality of phalanx of finger	HPO Gene-Disease Associations	1.0	null
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU1197	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9956
Hereditary retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.136
BRD-K31110422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33404
Kinesin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.781
BRD-K07160568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2057
Sarcoma_SARC_TCGA-UE-A6QT-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61527
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.0741
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.874
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.582019
Perturb_17574_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.92685
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47385
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36985
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15871
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10056
Vitreous disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
Perturb_4669_OE_Wdr5/Trp53|Wdr5_SRP324834	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_1127_KO_Myc_SRP168941	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.35483
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64129
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.741
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11969
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4353
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	1.4856
X-linked cone-rod dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
CRCGN017_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0973
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00866
Eye degenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841078
Perturb_13254_KD_Ncaph2_SRP073037	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.01636
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988131
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.11775
HN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41041
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.82126
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.399363
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06736
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44526
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.727052
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57633
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26876
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K58253880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47331
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00432
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14438
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.234
Mueller cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
UBE2V2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42295
Perturb_2875_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_1684_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.63562
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051289
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29186
HCaRG_OE_GDS1411_72_human_HEK293 embryonal kidney cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.815
Perturb_5201_KD_Wdr43_SRP132494	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.33369
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06977
CHD1-19587682-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.388
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43372
BRD-K20525312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62518
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56373
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50284
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6953-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836792
KYM1	DepMap CRISPR Gene Dependency	1.0	2.9161
BRD-K75869048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64865
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.666
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61156
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43782
recessive	GeneRIF Biological Term Annotations	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
Congenital stationary night blindness autosomal dominant 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
cilia	GeneRIF Biological Term Annotations	1.0	null
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Orofaciodigital syndrome IX	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	2.56126
BRD-K67087027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21539
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7Q1-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	5.63097
BRD-K35080107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2227
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the lower urinary tract	HPO Gene-Disease Associations	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977292
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
NCIH2171	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
florfenicol-3083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887017
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
Perturb_15663_KD_Hnrnpu_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.04113
Perturb_16721_KO_Brca1_SRP094855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.16291
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119798
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Perturb_5158_KD_Zic3_SRP046299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.8574
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79934
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0078
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931986
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947068
PMC8196557__F6	PFOCR Pathway Figure Associations 2024	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
children	GeneRIF Biological Term Annotations	1.0	null
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8935
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2791
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03828
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01119
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29835
Retinal detachment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
aplasia/hypoplasia affecting bones of the axial skeleton	HPO Gene-Disease Associations	1.0	null
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83714
Perturb_2232_KO_Rela_ERP122918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal retinal layer morphology	MPO Gene-Phenotype Associations	1.0	null
cSARS Bat SRBD_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.82943
Usher syndrome type 2C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20411
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87374
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07763
PLEKHH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55571
GTEX-XXEK-2026-SM-4BRVE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10199
BRD-K33283629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09093
BRD-K84935293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10609
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.26794
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42248
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07309
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MZ7-mel	GDSC Cell Line Gene Expression Profiles	-1.0	-1.75778
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00857
aplasia/hypoplasia of the cerebellum	HPO Gene-Disease Associations	1.0	null
ATP6V0B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40172
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12468
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.0054
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25598
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886215
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
microtubule cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-6216-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35236
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6012
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16527
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00988
biological_process	GO Biological Process Annotations 2015	1.0	null
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27827
GSE180200,GSE180201_3_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COV434	Achilles Cell Line Gene Essentiality Profiles	1.0	1.84711
eye photoreceptor cell development	GO Biological Process Annotations 2025	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6657
BRD-K59957369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12205
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0659
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr14_21310429_G_A_b38	GTEx eQTL 2025	1.0	1.90681
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19135
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59223
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41465
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.948673
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.255
RPGR	Pathway Commons Protein-Protein Interactions	1.0	null
Retinitis pigmentosa 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.814
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5841
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29505
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.256
spina bifida	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185612
layer 4 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17476
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1255
abnormality of globe location	HPO Gene-Disease Associations	1.0	null
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.929654
BRD-K68485855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80726
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04298
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67767
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55257
BRD-K30198800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.759
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Age Related Macular Degeneration	DisGeNET Gene-Disease Associations	1.0	null
GID complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
BRD-K00119817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62324
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.41
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67348226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08964
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68542
bodies	GeneRIF Biological Term Annotations	1.0	null
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37951
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_16443_KO_Kdm5b_SRP291684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.06638
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95591629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11545
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	0.870174
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08555
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15661_KD_Hnrnpc_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.02321
Cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.509
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4678
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31687
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	1.89067
Joubert syndrome 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908398
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51126
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
Anteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24532
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	1.56513
occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245175
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95626
Red color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49177
Eye-eye photoreceptor cell	Tabula Sapiens Gene-Cell Associations	1.0	9.73743
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858949
Sperm principal piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
Centriolar subdistal appendage	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.805
perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.209169
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
Perturb_15611_KO_Nampt_SRP065603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.59613
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.746
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94151
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
Perturb_13358_KD_Irf1_SRP234803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.40437
steroid-induced glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
BRD-K78828094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60267
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.7724
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03892
alteration	GeneRIF Biological Term Annotations	1.0	null
abnormal spatial orientation of the cardiac segments	HPO Gene-Disease Associations	1.0	null
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03892
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31907
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6863
fixation	GeneRIF Biological Term Annotations	1.0	null
knowledge	GeneRIF Biological Term Annotations	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997732
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09755
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.22342
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998035
BRD-K08650286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00668
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04521
Retinitis pigmentosa 87	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46551
heterozygous	GeneRIF Biological Term Annotations	1.0	null
Perturb_5700_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.92685
Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Secondary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6012
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916185
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6859
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040755
cerebellar cyst	HPO Gene-Disease Associations	1.0	null
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
sensory perception	GO Biological Process Annotations 2015	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21229
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18205
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40285
rpe65	GeneRIF Biological Term Annotations	1.0	null
Perturb_3122_KO_Slc6a14_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.14928
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.52855
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4326_KO_Zcchc8_SRP187429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.50748
Retinitis pigmentosa 32	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95626
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A113-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07218
BRD-K21200579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08918
sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08019
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964216
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07312
TAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07576
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32539
abnormality of the cerebellar vermis	HPO Gene-Disease Associations	1.0	null
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25164
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15714
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0149
LCLC-103H	GDSC Cell Line Gene Expression Profiles	-1.0	-2.38452
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40564
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60946512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39488
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78691
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nicotine addiction_Ganglioneuroblastoma_GSE11208	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.17782
GSE88819_0_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02611
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170114
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08836
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49272
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860275
cause	GeneRIF Biological Term Annotations	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.879252
NCI-H2171	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.47698
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4491
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910808
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3985
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Perturb_203_KD_Id1/ld3_SRP193147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.87501
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Proximal portion of axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.141
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49824
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67897
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850865
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942933
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.513
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1575
Perturb_13305_KD_Zfp207_SRP308674	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.45765
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13524
Lung adenocarcinoma_LUAD_TCGA-55-6979-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polydactyly	DisGeNET Gene-Disease Associations	1.0	null
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890159
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06609
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928205
GSE211963_0_v_3_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11321995-41556_2024_1460_MOESM2_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Unique_genes_with_exons_significantly_correlated_with_OTX2_expression_in_Group_3_and_Group_4_MB_tumors_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914292
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3347-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Fatty Liver	CTD Gene-Disease Associations	1.0	1.23265
HUPT4	DepMap CRISPR Gene Dependency	1.0	3.51248
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.902
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47718
Perturb_1678_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.85874
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32856
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.544
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953061
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.088
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
cone-rod dystrophy 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
weakness due to upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
cilium	GeneRIF Biological Term Annotations	1.0	null
GSE58724_3_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0613
Infantile Refsum disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K27092365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36055
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09013
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7554
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856112
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85696
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18505
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10158
BRD-K50965411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02421
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27011
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3322
Perturb_10361_KO_Arid5a_SRP288358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CAV3_Deficiency_GDS3552_558_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81412
Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
BRD-K50092006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23962
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cone-rod dystrophy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
Color Vision Defect	DisGeNET Gene-Phenotype Associations	1.0	null
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72431
preaxial polydactyly	HPO Gene-Disease Associations	1.0	null
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
BRD-K54945117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76411
Retinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.06104
Cataract	DisGeNET Gene-Disease Associations	1.0	null
TE10	DepMap CRISPR Gene Dependency	1.0	3.22813
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03691
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59291
abnormal photoreceptor outer segment morphology	MPO Gene-Phenotype Associations	1.0	null
Presubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15342
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23318
BRD-K22564762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24709
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.125062
BRD-K15380626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12668
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.70415
Brain Lower Grade Glioma_LGG_TCGA-CS-6290-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
HCC1500	CCLE Cell Line Gene Mutation Profiles	1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2379
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Perturb_16832_OE_Myc_SRP250081	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.18315
ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.364139
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2296
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K66838288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.707
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44635
KATOIII	CCLE Cell Line Gene Mutation Profiles	1.0	null
Perturb_13004_KO_Upf2_SRP309261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.31072
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Interphotoreceptor matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.39
PMC10204296-13578_2023_1034_MOESM16_ESM.xlsx-Black-ZNF671_ZNF671	Rummagene Transcription Factor Associations 2026	1.0	null
Adventitious root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
BRD-K50330857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.445
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.822
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.106088
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958509
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
rt4	HPA Cell Line Gene Expression Profiles	1.0	1.85171
Primary open angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.734
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
Perturb_5711_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-SNOS-0926-SM-4DM7A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02132
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
recessive cone-rod dystrophy	GAD Gene-Disease Associations	1.0	null
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10911
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838079
Perturb_13847_KO_Mov10_SRP091426	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.89897
Perturb_5043_KO_Adnp_SRP313259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.7714
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049553
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3818
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875196
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.61856
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4363
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.586
Perturb_943_KO_Sftpa1_SRP246320	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.81597
Perturb_3232_KO_Pou2af1_SRP293293	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.8449
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11212
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17397
abnormality of the urethra	HPO Gene-Disease Associations	1.0	null
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.358
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905532
involves	GeneRIF Biological Term Annotations	1.0	null
leber congenital amaurosis 6	OMIM Gene-Disease Associations	1.0	null
SW48	CCLE Cell Line Gene Mutation Profiles	1.0	null
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06458
ChIP_SMAD1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14188
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5365
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37748
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082683
Nanophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pentolinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0949
developmental process	GO Biological Process Annotations 2015	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33107
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70102
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C3-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41831
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.28
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.37221
Exudative vitreoretinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13238_KO_Flcn_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.68635
RMUGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.03821
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15252
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.3577
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894667
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.724
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55374
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28155
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02895
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87792
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72479
Perturb_13266_KO_chr3_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.2218
GSE126402_2_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.05013
aclarubicin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39544
Congenital Blindness	DisGeNET Gene-Disease Associations	1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16442
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
sloping forehead	HPO Gene-Disease Associations	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11752
BRD-K85802892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75825
Perturb_12568_KD_Sufu_SRP194252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843575
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06594
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.477
Perturb_15275_OE_Foxa1_SRP189075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04219
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.19298
Perturb_4711_KO_Sox9_ERP109172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.86043
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Eye disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92986
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53052
Perturb_5124_KD_Med28_SRP325525	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.94204
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5314
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.195383
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5222_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.5037
Lung adenocarcinoma_LUAD_TCGA-69-7974-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interact	GeneRIF Biological Term Annotations	1.0	null
juvenile	GeneRIF Biological Term Annotations	1.0	null
Attenuation Of Retinal Blood Vessels	DisGeNET Gene-Phenotype Associations	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K76680796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21662
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47402
Spinocerebellar ataxia type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23702
axoneme part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.458803
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
Retinal macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79302
isoform	GeneRIF Biological Term Annotations	1.0	null
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.89436
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04386
HUNS1	DepMap CRISPR Gene Dependency	1.0	2.66291
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12506
precuneus, left, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.908257
BRD-K14989228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79216
Perturb_13569_KD_Crebl2_SRP214575	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54123
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50099
Medullary collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33804
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41798816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65049
LI7	CCLE Cell Line Gene Mutation Profiles	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13099
absent photoreceptor outer segment	MGI Mouse Phenotype Associations 2023	1.0	null
ES4	DepMap CRISPR Gene Dependency	1.0	4.39151
BRD-K87927290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47313
posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
Retinitis Pigmentosa	CTD Gene-Disease Associations	1.0	2.88009
BRD-K23162004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02276
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
neurodegeneration	MPO Gene-Phenotype Associations	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061538
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85696
BRD-K32051704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0893
BRD-K77252933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20411
emerges	GeneRIF Biological Term Annotations	1.0	null
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
16740760-TableS1	GeneSigDB Published Gene Signatures	1.0	null
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-2.09482
Familial Aplasia Of The Vermis	DisGeNET Gene-Disease Associations	1.0	null
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
Chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
abnormality of the spleen	HPO Gene-Disease Associations	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75637
leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.62156
SPTAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10078
Autosomal recessive polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832165
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.454
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47524
Rebound Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.88445
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nonsynonymous	GeneRIF Biological Term Annotations	1.0	null
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85696
L33	CCLE Cell Line Gene Mutation Profiles	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.89634
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2888-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3728_OE_Fut9_SRP242022	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.79924
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892078
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965863
Leber congenital amaurosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.473
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-0.873941
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44261
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.878696
color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133801
cilium	GO Cellular Component Annotations 2025	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21273
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1826
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29579
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09597
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22121
immune system disease	GWASdb SNP-Disease Associations	1.0	0.053646
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826703
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61338
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25622
abnormality of the cerebrospinal fluid	HPO Gene-Disease Associations	1.0	null
Bardet-Biedl syndrome 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
Perturb_4987_KO_Mettl3_SRP212677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.77448
FAAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40091
FOXA2	ChEA Transcription Factor Targets	1.0	null
cone-rod dystrophy	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48272
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01458
CRCGN015_MCF10A.TP53.M_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04218
CCK81	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831423
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88029
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98312
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.328
BRD-K49328983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52106
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865479
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1385	CCLE Cell Line Gene Mutation Profiles	1.0	null
16166618-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
BRD-K43282617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2966
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01003
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.426186
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64642
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01539
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
Brain Lower Grade Glioma_LGG_TCGA-HT-7473-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diabetic Neuropathy_Sciatic Nerve_GSE11343	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53204
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.29007
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chromosome 3q13.31 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
decreased a-wave amplitude	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_3238_KO_Bach2_SRP359277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.51356
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03787
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58841
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6459
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.814
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	2.1119
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66595
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35104
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07185
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38126
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COV644	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21627
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01186
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839106
Perturb_3418_KO_Satb2_SRP256439	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.41731
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03287
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948168
centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.527569
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83W-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.07625
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13497
Perturb_12128_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958509
Photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49552
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59162
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
Full Cheeks	DisGeNET Gene-Phenotype Associations	1.0	null
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22073
ALG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52304
abnormal somatic sensory system morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K47098496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63937
Perturb_11511_KD_Fbxo22_SRP170074	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.7167
BRD-K97468369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5594
abnormality of the orbital region	HPO Gene-Disease Associations	1.0	null
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.206
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04745
Photoreceptor cell cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34148
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089155
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30807
abnormal retinal photoreceptor layer morphology	MPO Gene-Phenotype Associations	1.0	null
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60652
Permanent Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
Perturb_16697_KO_70L02Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.28234
Leber congenital amaurosis 6	ClinVar Gene-Phenotype Associations	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7907-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aplasia/hypoplasia of the  cerebellar vermis	HPO Gene-Disease Associations	1.0	null
Exoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
HNRNPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88249
PMC12158781-41586_2025_8915_MOESM5_ESM.xlsx-THP1_synergy_up-Gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IS-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08654
Perturb_9545_KO_Ucp1_SRP187003	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.81251
cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K24109044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16206
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
BRD-K92891227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61598
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92277
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03787
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.614
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38199
neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16233
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15673_KD_Hnrnpk_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.89963
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2902
Necrosis	CTD Gene-Disease Associations	1.0	1.08797
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87792
BRD-K62942008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48221
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58509
roles	GeneRIF Biological Term Annotations	1.0	null
Perturb_3083_KO_Elmo3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.60837
BRD-K78500251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74376
abnormality of the choroid	HPO Gene-Disease Associations	1.0	null
TFEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12426
axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.829089
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39274
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47547
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
postaxial foot polydactyly	HPO Gene-Disease Associations	1.0	null
Perturb_15769_KO_Uxt_SRP240277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.5008
Perturb_12007_KO_B2_Mm2_SRP374407	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.88537
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.76825
Retinal Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE136233,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10911
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904145
D423MG	DepMap CRISPR Gene Dependency	1.0	9.22257
Male Pseudohermaphroditism	DisGeNET Gene-Disease Associations	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18064
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23512
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29543
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1699
photophobia	HPO Gene-Disease Associations	1.0	null
STAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17348
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41149
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
STX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33263
abnormality of the cheeks	HPO Gene-Disease Associations	1.0	null
Retraction Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K76748254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20134
feature	GeneRIF Biological Term Annotations	1.0	null
Perturb_13579_KD_Fem1b/Keap1_SRP274135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.56013
corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054013
visual impairment	HPO Gene-Disease Associations	1.0	null
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2588
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03426
SIN3A	ChEA Transcription Factor Targets	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09599
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72633
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cone-rod dystrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.256
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.57281
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spontaneous Ocular Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4597
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990354
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4078
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18993
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849577
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46944
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78224
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
MDAMB175VII	CCLE Cell Line Gene Expression Profiles	1.0	1.36302
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50954
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4528
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
HCC1395	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.82395
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976098
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.956
BRD-K76088420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02881
cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.78004
JAR	DepMap CRISPR Gene Dependency	1.0	2.06888
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32618
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.41206
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16978
Joubert syndrome 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86663
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinitis pigmentosa 86	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0389
Aplasia/Hypoplasia Of The Corpus Callosum	DisGeNET Gene-Phenotype Associations	1.0	null
rpgrip1l	GeneRIF Biological Term Annotations	1.0	null
Extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
Meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.877
TE14	CCLE Cell Line Gene CNV Profiles	1.0	2.14972
other	GAD High Level Gene-Disease Associations	1.0	0.293278
RUNX1	ChEA Transcription Factor Targets	1.0	null
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.21623
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.90518
CPC-N	GDSC Cell Line Gene Expression Profiles	1.0	1.8874
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23542
hypermetropia	HPO Gene-Disease Associations	1.0	null
GSE217441,GSE217443_1_v_0_ivosidenib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43605
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88934376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03377
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4758
BRD-K83935370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17694
BRD-K74632893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14598
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17805
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04639
abnormality of the external nose	HPO Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91703
Cranioectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
macular degeneration	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08922
HS 839.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27229
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88115
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13823
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01628
Perturb_14923_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.48003
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41945
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4816-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01251
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27237
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06158
BRD-K02839126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10586
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83135
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895692
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pseudoretinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
been	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.8705
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.488923
Microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.207
SW837	CCLE Cell Line Gene Mutation Profiles	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.0134
Node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
Perturb_15901_KD_Jun_SRP361315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.18562
Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85649
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
severe visual impairment	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.65975
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01792
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43266
Bardet-Biedl syndrome 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
CRCGN016_MCF10A.WT.HP_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57115
SNU478	DepMap CRISPR Gene Dependency	1.0	2.28512
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999771
abnormality of the fundus	HPO Gene-Disease Associations	1.0	null
abnormality of the curvature of the cornea	HPO Gene-Disease Associations	1.0	null
PMC7515907__F3	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_13268_KO_chr2_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.34123
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64648
SNU1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48449
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16342
SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.33533
pgrinteracting	GeneRIF Biological Term Annotations	1.0	null
Perturb_12008_KO_B2_Mm2_SRP374407	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.20648
muscular hypotonia	HPO Gene-Disease Associations	1.0	null
defined	GeneRIF Biological Term Annotations	1.0	null
Collecting duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.921394
Retinitis pigmentosa 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59017
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
Nyctalopia	DisGeNET Gene-Disease Associations	1.0	null
increase	GeneRIF Biological Term Annotations	1.0	null
BRD-K34695725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23979
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.485
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25885
ANAPC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03596
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9275
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23512
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4602_KO_Mst_SRP246200	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.14701
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
high-grade hypermetropia	HPO Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUS-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13796
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02626
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.25337
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11715
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14944_KD_Nmnat1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.21565
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04559
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YK-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.895828
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05553
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.549
intermediate stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21843
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48747
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93937
BRD-K67896259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62668
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06252
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
abnormality of neutrophils	GWASdb SNP-Phenotype Associations	1.0	0.378764
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20556
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8209
polydactyly	HPO Gene-Disease Associations	1.0	null
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
basal	GeneRIF Biological Term Annotations	1.0	null
succinylcholine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.08796
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03059
abnormality of the retina	HPO Gene-Disease Associations	1.0	null
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.451
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2825
colocalizes	GeneRIF Biological Term Annotations	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050866
PREPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49161
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21893
amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.477151
Achromatopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.636
leber	GeneRIF Biological Term Annotations	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0405
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.1476
segments	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6559_KO_Rabl2_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Pendular Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5342
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12468
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.879097
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24405
BRD-K03116744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02061
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.084902
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972461
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
hydrocephalus	HPO Gene-Disease Associations	1.0	null
placenta_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.884747
disorganized photoreceptor outer segment	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_13230_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.3751
Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68507
dactinomycin_mus musculus_gpl1261_wild type_gds2456	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984656
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40115967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49741
Perturb_8509_KO_Bmal1_ERP009958	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.67461
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0405
Perturb_5114_KD_Med12_SRP325525	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.86735
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2105
male pseudohermaphroditism	HPO Gene-Disease Associations	1.0	null
retinal spots	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	2.19404
Horizontal Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	0.974446
periphery	GeneRIF Biological Term Annotations	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.08975
BRD-K02624724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99039
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43293
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26036
Perturb_3130_KO_Thpo_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.56659
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0939
BRD-K51791049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12431
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875629
series	GeneRIF Biological Term Annotations	1.0	null
ZNF839	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41876
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07305
Perturb_8015_KD_Crebl2_SRP214573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34222
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89835
D-283MED	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.5282
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.032
nucleocytoplasmic	GeneRIF Biological Term Annotations	1.0	null
BRD-K16539011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63264
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.198991
Perturb_15737_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.0937
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.2924
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.02447
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
Ciliary pocket membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
ZR7530	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.3016
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13099
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944303
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1486
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03297
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6878
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59597
Mesothelioma_MESO_TCGA-SH-A7BC-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2892
COGN278	DepMap CRISPR Gene Dependency	1.0	2.71184
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6307
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06975
K562	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19287
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.129673
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.483273
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988166
C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02035
cognitive impairment	HPO Gene-Disease Associations	1.0	null
Perturb_5261_KO|KD_Mir290a/Mir290b/Mir291a/Mir292/Mir292/Mir291b/Mir293/Mir294/Mir295|Tfap4_SRP326984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.51016
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orf15	GeneRIF Biological Term Annotations	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2578
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4631
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.20287
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19658
SKBR3	CCLE Cell Line Gene Expression Profiles	1.0	2.02666
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.98118
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09535
abnormal posterior eye segment morphology	MPO Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12806_OE_miR106b_ERP132601	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55133
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cone-rod dystrophy 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.082
Perturb_13273_KO_Spen_SRP198728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.0799
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094575
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23975
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10836
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
Hepatic Fibrosis, Congenital	DisGeNET Gene-Disease Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21368
Kidney Chromophobe_KICH_TCGA-KN-8424-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.18173
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.859
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94789
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81814
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08228
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051843
Hypoglossal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09861
BRD-K38970027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04415
strongly	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03882
CRCGN011_HEPG2_24H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2763
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.65145
Perturb_216_KO_Gpd2_SRP361070	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.24523
SNU423	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59463
microcornea	HPO Gene-Disease Associations	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14376
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.03825
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7896
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48242
nucleus subceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.86672
SKMEL24	CCLE Cell Line Gene Mutation Profiles	1.0	null
Severe acute respiratory syndrome (SARS)_Peripheral blood mononuclear cell_GSE1739	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.27428
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
placenta	HPA Tissue Gene Expression Profiles	1.0	1.16771
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059995
senior-loken syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.833968
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.96286
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.049
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.848288
BRD-K90697691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63954
BRD-A26583774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73816
9+0 non-motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Bestrophinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
CRCGN017_MCF10A.TP53.M_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0358
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10623
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99393
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07057
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95201
intracellular part	GO Cellular Component Annotations 2015	1.0	null
increased corneal curvature	HPO Gene-Disease Associations	1.0	null
Usher syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
NB7	DepMap CRISPR Gene Dependency	1.0	2.85574
BRD-K67217705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02822
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41702
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97415
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40493
PMC6047740__F6	PFOCR Pathway Figure Associations 2024	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02717
dilated fourth ventricle	HPO Gene-Disease Associations	1.0	null
Partial central choroid dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
Renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943087
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.09348
abnormality of digit	HPO Gene-Disease Associations	1.0	null
BRD-K65824451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08916
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89201
abnormality of neuronal migration	HPO Gene-Disease Associations	1.0	null
recent	GeneRIF Biological Term Annotations	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95626
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846249
HCC2935	CCLE Cell Line Gene CNV Profiles	1.0	1.37509
congenital	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4937
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09061
MCAD_KO_GDS4546_423_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03858
Symptomatic Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.087
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.66057
Perturb_11806_KO_H1foo_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.99083
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39332
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98089
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Centrosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.162
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22005
visual loss	HPO Gene-Disease Associations	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.348
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
D283MED	CCLE Cell Line Gene Expression Profiles	1.0	3.40786
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
BRD-K50432649	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42649
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
Perturb_15828_OE_Nrf2_SRP291726	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.20539
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70751
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.100912
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GS-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary rootlet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.115
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00407
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5278
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01057
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06403
icSARS-Cov_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.30483
Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X-linked cone-rod dystrophy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42348
leukocyte disease	GWASdb SNP-Disease Associations	1.0	0.32375
Choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.25
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991312
abnormal eye physiology	MPO Gene-Phenotype Associations	1.0	null
BC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.032
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43223
IGROV1	CCLE Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.8429
HSFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29153
Optic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.80849
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07608
restricted	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.03159
BRD-K61072684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18703
GTEX-S3XE-0326-SM-4AD6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906983
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25352
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77953
BRD-K26734305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04074
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33507
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.966
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08107
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01509
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.898
HEC6	CCLE Cell Line Gene Mutation Profiles	1.0	null
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
Perturb_13264_KO_chr7_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.7922
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.815
HSC-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.244
Perturb_10350_KD_Zbtb17_ERP119985	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.08195
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7888619-pgen.1009309.s032.xlsx-S9_Table-S9_Table_Predicted_target_genes_of_POU3F2_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01999
Heterotrimeric G-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.929
postcentral gyrus, left, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05238
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17481
abnormality of the optic nerve	HPO Gene-Disease Associations	1.0	null
HER2_KO_GDS4056_567_human_breast biopsies	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5621
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39332
nucleophosmin	GeneRIF Biological Term Annotations	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69369
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4973
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
Centriolar satellite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.561
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
model	GeneRIF Biological Term Annotations	1.0	null
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pramocaine-4368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36948
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35795
BRD-K85216683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28533
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43437
Acute Myeloid Leukemia_LAML_TCGA-AB-2815-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913237
anomaly of the limb diaphyses	HPO Gene-Disease Associations	1.0	null
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00392
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.926752
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0279
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
GTEX-WWYW-0426-SM-3NB31	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21094
Cytoplasmic ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47786
Kidney Chromophobe_KICH_TCGA-KN-8425-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-70-6723-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.69905
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-XS-A8TJ-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.65
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18677
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923854
Abnormal Chorioretinal Morphology	DisGeNET Gene-Disease Associations	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07052
octreotide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-6.0524
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2512
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.50023
low-set, posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
cystic liver disease	HPO Gene-Disease Associations	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23627
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.924947
non-motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39621
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52738
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Usher syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
Blindness	HuGE Navigator Gene-Phenotype Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0259
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0554
Ventromedial hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47384
BRD-K21936026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41758
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89201
GTEX-SIU7-0226-SM-4BRX2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872479
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94799
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69529
microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.352522
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04607
BRD-K13320013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29986
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825486
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.862543
SK-HEP-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.45986
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.85948
Convergence Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K62294866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31711
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	1.0	2.26967
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.233183
ambiguous genitalia	HPO Gene-Disease Associations	1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887179
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
encephalocele	HPO Gene-Disease Associations	1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89865
often	GeneRIF Biological Term Annotations	1.0	null
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.960303
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05119
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69486
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72924
CTIP_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
sf-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192224
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1758
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75102
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03722
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42416
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052392
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174635
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RN-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pericycle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.653
Senior-Loken syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.839
H2595	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.095
BRD-K92826631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43294
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.442
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11697
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03787
dorsolateral part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57689
SK-MG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DB-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23491
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.551425
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66159
area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387781
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32658
described	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the cerebellum	HPO Gene-Disease Associations	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050365
mt-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61175
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.821
Embryonic neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.262
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.667
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7611
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961818
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17177
BRD-K45908502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2465
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02872
BRD-K76005262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34756
BRD-K04108962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19214
BRD-K22661969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42936
patient	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4824-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09413
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57652
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6869
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5159
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18008
Casparian strip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Lung Injury_Lung Tissue_GSE1541	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48358
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05281
Perturb_10241_KO_Crat_SRP394715	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.42482
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye and adnexa disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2649
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23438
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.961
bowing of the long bones	HPO Gene-Disease Associations	1.0	null
BRD-K82021299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35341
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09678
BB30HNC	DepMap CRISPR Gene Dependency	1.0	2.1983
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00254
causing	GeneRIF Biological Term Annotations	1.0	null
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29506
Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23604
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863543
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18908
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47545
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28072
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828981
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.431435
GTEX-OHPL-0426-SM-3TW8X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.871867
Meckel syndrome 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.668
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07207
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.48539
BRD-K13542161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13917
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.05274
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83845
Lobar Holoprosencephaly	DisGeNET Gene-Disease Associations	1.0	null
GTEX-VJYA-1226-SM-3GIJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834042
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.56701
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
HCC1195	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
McKusick-Kaufman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.857
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36757
crb1	GeneRIF Biological Term Annotations	1.0	null
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
thin retina outer nuclear layer	MGI Mouse Phenotype Associations 2023	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83611
BRD-K32472782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42952
ZNF10	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25878
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Bleb	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
GSE88819_11_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
cell development	GO Biological Process Annotations 2015	1.0	null
See-Saw Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862456
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95473
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31804
Fer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K52492854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72952
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95323
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.958839
Retinitis pigmentosa 37	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
cell part	GO Cellular Component Annotations 2015	1.0	null
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07497
Perturb_18555_KD_miR466c_SRP319883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.96985
Perturb_13067_KO_Ube3d_SRP373803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.2004
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04932
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05791
BRD-K95114614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02302
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04712
Optic disk drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
CRCGN015_MCF10A_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21345
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23512
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Occult macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
SCYL1_knockdown_194_GSE57646	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.20035
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.56915
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16403_KO_Grpel1_SRP363877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.50791
TSHZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17186
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal diaphysis morphology	HPO Gene-Disease Associations	1.0	null
PMC7515907__F3	PFOCR Pathway Figure Associations 2024	1.0	null
abnormal retina morphology	MPO Gene-Phenotype Associations	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923041
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43054
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28817
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105059
cloperastine-3608	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0969
SW1710	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46897
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6208
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.15
fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.94501
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054421
leber congenital amaurosis	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH2	DepMap CRISPR Gene Dependency	1.0	2.47218
MBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95527
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03787
True Hermaphroditism (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56505
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
replacement	GeneRIF Biological Term Annotations	1.0	null
open-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.139648
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
BRD-K12177722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00898
Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
GSE126777_0_v_1_otub1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27938
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.17177
Sloping Forehead	DisGeNET Gene-Phenotype Associations	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.8171
lca	GeneRIF Biological Term Annotations	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10574
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.891643
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.4151
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
NCIH838	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42213
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00183
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
clinically	GeneRIF Biological Term Annotations	1.0	null
18625725-TableS1	GeneSigDB Published Gene Signatures	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_4day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74598
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	1.37843
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LN340	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35555
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K62263376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15354
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.8715
SK-MEL-24	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14739
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU738	CCLE Cell Line Gene Expression Profiles	1.0	2.05829
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27939
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinitis pigmentosa 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
RBPJ	ChEA Transcription Factor Targets	1.0	null
Nephronophthisis 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.042
Vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49715
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4165
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2323
NCIH1793	CCLE Cell Line Gene Expression Profiles	1.0	1.44623
HAUS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70929
HEC108	CCLE Cell Line Gene Mutation Profiles	1.0	null
targeted	GeneRIF Biological Term Annotations	1.0	null
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65603
ACHN	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66339
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73291
Congenital nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51112
MS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.40924
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.804
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
evident	GeneRIF Biological Term Annotations	1.0	null
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15671
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.41465
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13303
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14064
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.38113
BRD-K19310540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06881
abnormality of the palate	HPO Gene-Disease Associations	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cone-rod dystrophy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4514
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.68712
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299242
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4176-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
first (dorsal) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05519
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.56175
Joubert syndrome with orofaciodigital defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.821
BT474	CCLE Cell Line Gene CNV Profiles	1.0	1.61099
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PDX1_KO_GDS4348_360_mouse_Proximal small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972396
Rotary Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
oral cleft	HPO Gene-Disease Associations	1.0	null
BRD-K53198140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24975
abnormality of the head	HPO Gene-Disease Associations	1.0	null
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42085
Color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.606
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45888106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50841
GAS2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39798
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
aplasia/hypoplasia of the tongue	HPO Gene-Disease Associations	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5185
Retinitis pigmentosa 45	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
SYDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75144
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.9992
zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.405193
Perturb_4836_KO_Chd8_SRP306703	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93618
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14674
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37304
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K80880506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73958
Perturb_16086_KO_Bap1_SRP270239	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.96495
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75755
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.931392
abnormality of the midface	HPO Gene-Disease Associations	1.0	null
Electroretinogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMM1	DepMap CRISPR Gene Dependency	1.0	4.00733
GTEX-Q2AG-0326-SM-48U1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01187
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.071848
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907131
Perturb_12569_KD_Sufu_SRP194252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868154
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.46316
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.843903
BRD-K45941986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32928
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.5536
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4817-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Sporophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
Neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.14
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10138
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05129
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_12hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938498
colocalize	GeneRIF Biological Term Annotations	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4974
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05659
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950377
OV7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05325
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230409
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2983
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
GSE223334_1_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cataract	HPO Gene-Disease Associations	1.0	null
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52278
Interphotoreceptor matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.916
BRD-K05474024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25422
PANC-08-13	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
NUGC3	CCLE Cell Line Gene Mutation Profiles	1.0	null
CAV1_Deficiency_GDS3551_559_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.403
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SF268	DepMap CRISPR Gene Dependency	1.0	2.11761
BRD-K09943620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09494
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.927958
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55197
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.4687
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11665559-jciinsight-9-183889-s131.xlsx-Fig2DiffBind_MYB_TR-PLEvsNTC-WT-Nearest_Ensembl_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Joubert syndrome 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.628
Hypertrophy	CTD Gene-Disease Associations	1.0	1.58374
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07931
conerod	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840628
night blindness	HPO Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00974
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22655
abnormality of lower limb bone	HPO Gene-Disease Associations	1.0	null
Jerk Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25443
BRD-K38633800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13379
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
C2BBE1	CCLE Cell Line Gene Mutation Profiles	1.0	null
true hermaphroditism	HPO Gene-Disease Associations	1.0	null
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36282
Lung adenocarcinoma_LUAD_TCGA-62-8394-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02563170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16605
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834567
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.313
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12063
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26297
Lateral root primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.461
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.84578
ARHGEF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30083
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72263
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58645
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30473
DCC	MSigDB Cancer Gene Co-expression Modules	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	2.27793
Enhanced S-cone syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13963
Perturb_11031_KO_Slc45a3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.35292
Retinitis pigmentosa	ClinVar Gene-Phenotype Associations 2025	1.0	null
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pendular nystagmus	HPO Gene-Disease Associations	1.0	null
GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
abnormality of pancreas morphology	HPO Gene-Disease Associations	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.253
abnormality of corneal size	HPO Gene-Disease Associations	1.0	null
retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38042
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SMAD1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.766
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.041