association	dataset	threshold value	standardized value
PMC6928094-395_2019_765_MOESM6_ESM.xlsx-DEGs_AR11_vs_AR1-List_of_differentially_expressed_genes_in_AR11_vs_AR1_Negative_value_means_down-regulation_in_AR11_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
Perturb_16099_KO_Eed_SRP125082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.45806
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metoclopramide-3625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92599
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K93357133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37811
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993321
hsa-miR-499a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
orphenadrine-2318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93797
BRD-K43159427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56709
Weight Loss	CTD Gene-Disease Associations	1.0	1.03122
transporter activity	GO Molecular Function Annotations 2015	1.0	null
REST_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01735
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.56926
lisinopril-7403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.716
betamethasone-valerate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15243
BRD-K60287130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.471
BRD-K93993174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17931
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
dantrolene-3978	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915873
BRD-K74096348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33324
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51298794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61042
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.625
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.33711
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.623
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901029
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8257
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57476
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861558
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92525
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8503
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72833997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06558
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62703
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843466
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42117
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46196
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908863
BRD-K74116035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54597
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.10458
cholinergic	GeneRIF Biological Term Annotations	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.699853
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.8663
BRD-K35945596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0113
SK-MEL-28	GDSC Cell Line Gene Expression Profiles	1.0	2.09365
BRD-K08996393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40647
BRD-K50726251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02212
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2249
Fraser syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.371
Lymphatic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.975938
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81323
rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.556344
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36951
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.31307
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP3	DepMap CRISPR Gene Dependency	1.0	2.91579
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44238
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nigrostriatal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
Lung squamous cell carcinoma_LUSC_TCGA-18-4083-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132948,GSE132949_4_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79867
BRD-K34258713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48882
BRD-K81175414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20524
BRD-K14671528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31461
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11698
loss	GeneRIF Biological Term Annotations	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34183
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.92916
Perturb_13802_KO_Mettl14_SRP286301	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-626	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.18813
Lymphoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044737
Central nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
halcinonide-6040	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79484
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-2.18476
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91148
BRD-K86073842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0262
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.053947
RAB27B	Pathway Commons Protein-Protein Interactions	1.0	null
vancomycin-4423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02456
BRD-K80225716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00958
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
synapse part	LOCATE Curated Protein Localization Annotations	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60358
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K49681465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38489
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049951
GABPA	ENCODE Transcription Factor Targets	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lipid binding	GO Molecular Function Annotations 2015	1.0	null
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEMF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94669
RBFOX2_02_139	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63863
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844615
Neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.996
COPII vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09468
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.634838
Secretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.673
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40961
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17862
BRD-K66643401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09031
SETD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10903
rna	Phosphosite Textmining Biological Term Annotations	1.0	null
phosphatidylinositol binding	GO Molecular Function Annotations 2025	1.0	null
trans-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.529
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S3-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mouth disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.313
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72153
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33708
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.6
AKTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22066
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
PCM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7994
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Spleen volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.40969
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47849
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14201
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67059
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16281
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32555
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
KMM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5082
Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3412
Presynaptic active zone membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12222
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22726
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13203
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15981
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13129
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K96096022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11806
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2025	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85164
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052148
BRD-K70594121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25334
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91646
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69879
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Monogenic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
BRD-K40126748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40869
Tetanus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.29922
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95688447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48451
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04534
phosphatidylinositol binding	GO Molecular Function Annotations 2023	1.0	null
alcohol binding	GO Molecular Function Annotations 2015	1.0	null
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.752473
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30919
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.677238
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58844
Hypersensitivity reaction type IV disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860534
Inflammatory spondylopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
BRD-K39499927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14017
impaired	GeneRIF Biological Term Annotations	1.0	null
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02802
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.267
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K28764680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24971
BRD-K70530990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44382
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64328
Perturb_10302_KO_Col4a3_SRP048893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.8196
hsa-miR-1273g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amoxapine-4996	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB8A	Pathway Commons Protein-Protein Interactions	1.0	null
Physical disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.313
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22804
Cholesterol, LDL	dbGAP Gene-Trait Associations	1.0	0.101082
BRD-K98938484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27407
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43891
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3325
GSE100217_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88671309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45813
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29831
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829763
BRD-K97276563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24815
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_4_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dementia	GeneRIF Biological Term Annotations	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Dyskinetic Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Coronary Heart Disease	DisGeNET Gene-Disease Associations	1.0	null
PMC11588066-pnas.2410331121.sapp.pdf-98-GTF2IRD1_GTF2IRD1	Rummagene Transcription Factor Associations 2026	1.0	null
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91767
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12264
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77053
SAOS2	DepMap CRISPR Gene Dependency	1.0	2.19341
transition metal ion binding	GO Molecular Function Annotations 2023	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
correlated	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:N19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0967
BRD-K96284156	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15576
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42262
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58895
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046377
vesicle fusion	GO Biological Process Annotations 2015	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.071241
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.1475
protein complex	GO Cellular Component Annotations 2015	1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089431
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913824
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11234
hsa-miR-3155b	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2543
18223198-TableS3	GeneSigDB Published Gene Signatures	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the kidney	GWASdb SNP-Phenotype Associations	1.0	0.126983
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41985
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49628
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02088
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0504
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.79321
GSE131377_4_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CILK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55314
rabphilin	GeneRIF Biological Term Annotations	1.0	null
BRD-K21139023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.117
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09887
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6317
NB1	CCLE Cell Line Gene Expression Profiles	1.0	1.41329
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
BRD-K93391478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69867
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neurohypophyseal diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.634
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983453
phosphatidylinositol phosphate binding	GO Molecular Function Annotations 2023	1.0	null
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22555
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87141
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916659
BRD-K57724551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08788
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61398
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33941
BRD-A55063801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17099
BRD-A09988375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22637
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66145389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31601
22RV1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00557
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14304
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65269
BRD-K04680784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29559
Pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.17
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33458
BRD-K73669270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80282
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843466
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02643
Lung adenocarcinoma_LUAD_TCGA-44-6144-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10684867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25941
TEAD4	ENCODE Transcription Factor Targets	1.0	null
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45131
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.01345
tetryzoline-6069	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71259
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
GSE103003_1_v_0_zeb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46695
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853616
Prestwick-967-2925	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
bretylium tosilate-3394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sulfinpyrazone-3192	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.877522
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
Serum uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
BRD-K48407262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34825
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7706
diprophylline-1811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06500446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59547
BRD-K45044525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33939
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of granulocytes	GWASdb SNP-Phenotype Associations	1.0	0.291848
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65085
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04967
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54767
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66671
REST	MotifMap Predicted Transcription Factor Targets	1.0	null
KAT2B	ENCODE Transcription Factor Targets	1.0	null
BRD-K18768055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13694
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11532
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
BRD-K96834095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25659
hydralazine-4746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919205
stomach_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
MOLM-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05155
Perturb_6258_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-A81615860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00982
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cingulate cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.297
PIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75997
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
neuroblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068001
Postsynaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K21610715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22258
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.146931
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054496
BRD-K79562803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16744
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3488
nucleotide	GeneRIF Biological Term Annotations	1.0	null
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074463
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
BRD-K26251149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02807
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30564
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51197
CRCGN008_HEPG2_24H:I02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6789
Basal ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.07
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49547
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08159
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5353
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ACVR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53834
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K44861255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19557
BRD-K02403042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.54883
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.722
GSE142684_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE254155_1_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76215709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13864
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_12546_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.62599
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
clathrin binding	GO Molecular Function Annotations 2015	1.0	null
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29153
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80138
BRD-K04771555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11396
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47494
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.94072
BRD-K73149920	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76287
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
12037678-Table2	GeneSigDB Published Gene Signatures	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02575
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AGS	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32292
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22918
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7407
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949274
Nephrocyte diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922317
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25855
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05776
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093207
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92188
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12555
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27036
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01135
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15216
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32068
cortex	Phosphosite Textmining Biological Term Annotations	1.0	null
abnormality of the urinary system physiology	GWASdb SNP-Phenotype Associations	1.0	0.209089
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72825
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55608
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854466
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76871
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16943_OE_Mir181a1_SRP359086	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.34544
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.537812
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.1279
YH13	CCLE Cell Line Gene Expression Profiles	-1.0	-2.15413
reduction	GeneRIF Biological Term Annotations	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39968
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89828
ZNF133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41584
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88516
NCIH2030	DepMap CRISPR Gene Dependency	1.0	6.81399
vesicle-mediated transport	GO Biological Process Annotations 2023	1.0	null
BRD-K67572910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75537
Perturb_15804_KO_Atf3_SRP350242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CAMK2A	KEA Substrates of Kinases	1.0	null
Nephrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
plastid part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051487
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3155	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NY-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.849
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.60932
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.712
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE96991,GSE97117_3_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15243
coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52625
regulation of cellular localization	GO Biological Process Annotations 2015	1.0	null
BRD-K05086663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04682
suggestive	GeneRIF Biological Term Annotations	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870662
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63393
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SH2D2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39917
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Epilepsy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.15124
brain	Phosphosite Textmining Biological Term Annotations	1.0	null
phosphatidylinositol phosphate binding	GO Molecular Function Annotations 2025	1.0	null
CAL-51	GDSC Cell Line Gene Expression Profiles	-1.0	-2.4772
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67041
cerebellar	Phosphosite Textmining Biological Term Annotations	1.0	null
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990606
cancer	GWASdb SNP-Disease Associations	1.0	1.26936
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92344227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02399
SK-MEL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059693
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic lymphocytic leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
HS819T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25108
golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.192746
transmission	Phosphosite Textmining Biological Term Annotations	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nuclear outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.048
PCDHGC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49595
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.05872
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arciform density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.269
diphemanil metilsulfate-4416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91715
thiamine_rattus norvegicus_gpl2896_gse19292	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01472
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67706
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Gestational diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
Perturb_16097_KO_Eed_SRP125082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.10663
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.878173
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.50946
BRD-K36324810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17544
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62654
Triglycerides Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE131377_4_v_2_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
forskolin	Phosphosite Textmining Biological Term Annotations	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18738
BRD-K17570530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51525
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62320774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23737
oxprenolol-6145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.976
BRD-K40649636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09115
Perturb_1692_KO_Prmt5_SRP059561	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.6009
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6807
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fusiform vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.385
glimepiride-2809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC5303304-13073_2017_407_MOESM4_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S3_Genes_differentially_expressed_by_24h_RA_and_48h_Dox_co-treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08455
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CY-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
plasticity	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66717
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952408
SAP30	ENCODE Transcription Factor Targets	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.052002
LRF	MotifMap Predicted Transcription Factor Targets	1.0	null
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00296
intracellular protein transport	GO Biological Process Annotations 2015	1.0	null
h4s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
MATH1	MotifMap Predicted Transcription Factor Targets	1.0	null
Dentate gyrus mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.426
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02954
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51681402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86233
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.987684
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50837
valinomycin-5957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-940	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
BRD-K57443386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37216
GSE217363_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02555
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-1.25992
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01872
BRD-K44787496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3041
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
endometrium_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Synaptotagmin	InterPro Predicted Protein Domain Annotations	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_14003_OE_Kcna2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.3172
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K30326216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04732
CIDEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46264
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	126.916
Piebaldism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0592
neuronal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130539
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86765
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33047
cytoskeletal	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-A12372458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16857
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Subthalamic nucleus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.07
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826502
SIN3A	ChEA Transcription Factor Targets	1.0	null
BRD-K03141963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06355
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48281
melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.393936
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53353
ethisterone-3975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19186
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83057
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47427
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54767
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81757081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28271
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35516
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1437	DepMap CRISPR Gene Dependency	1.0	7.68218
CAOV4	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.64039
ACOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07038
BRD-K89377615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09476
BRD-K58193973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00917
Extrinsic component of organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RAB3C	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.592
CRCGN016_MCF10A.WT.HP_24H:B18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45969
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
zinc ion binding	GO Molecular Function Annotations 2023	1.0	null
recycling	GeneRIF Biological Term Annotations	1.0	null
BRD-A69110668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26132
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K13091682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18523
LDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7699
SK-MM-2	GDSC Cell Line Gene Expression Profiles	1.0	1.81395
Granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
Neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.599
calcium	Phosphosite Textmining Biological Term Annotations	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K95963125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50911
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66803
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15889
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.09482
BRD-K19040998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18498
POMGNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18728
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Coronary Artery Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95307
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64917
human immunodeficiency virus infectious disease	GWASdb SNP-Disease Associations	1.0	0.669037
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348519
Huntington Disease	DisGeNET Gene-Disease Associations	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A64523751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1641
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Pituitary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844615
BRD-K04426746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53009
Diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.36
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.327
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81649
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11196
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.41811
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
rab3a	GeneRIF Biological Term Annotations	1.0	null
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.2415
YWHAB	Hub Proteins Protein-Protein Interactions	1.0	null
APOD_OE_GDS3913_489_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
regulation of exocytosis	GO Biological Process Annotations 2015	1.0	null
Perturb_15775_OE_Nmnat1_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.32393
BRD-K13715646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52772
BRD-K50575036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35553
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74537
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6171
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69802
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31834
intracellular part	GO Cellular Component Annotations 2015	1.0	null
macromolecule localization	GO Biological Process Annotations 2015	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6285
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diabetic Nephropathy_Renal Tissue_GSE1009	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.571145
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830025
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043384
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.01182
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15135
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17008
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.093
BOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15897
Y-shaped link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
Hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68117
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.039
CRCGN017_MCF10A.WT.HP_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04155
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EBC1	DepMap CRISPR Gene Dependency	1.0	2.40564
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3120-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37925
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29896
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
BRD-K44759088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27342
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Panhypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.485
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44825
BRD-K04714488	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45859
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17547
organelle outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.115281
CRCGN017_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36767
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.902745
domains	GeneRIF Biological Term Annotations	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065042
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.823968
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
release	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29912
BRD-K12099407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30671
hsa-miR-4300	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cytosol	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-222	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9839
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97537859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62879
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11678
since	GeneRIF Biological Term Annotations	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.766804
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	2.23577
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839667
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.839
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25091
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
establishment of localization	GO Biological Process Annotations 2015	1.0	null
HEC6	DepMap CRISPR Gene Dependency	1.0	4.62112
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88958
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
MRPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
BRD-K14383477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35265
BRD-A36774080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49484
COA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01353
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00326
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substance abuse	GWASdb SNP-Disease Associations	1.0	0.373216
phosphate ion binding	GO Molecular Function Annotations 2025	1.0	null
abnormality of the level of lipoprotein cholesterol	GWASdb SNP-Phenotype Associations	1.0	0.628991
Muscle tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54028
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73759
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03243
hsa-miR-4466	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059844
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99497
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12569
protein-transport	Phosphosite Textmining Biological Term Annotations	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Low density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2301
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1734
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705173
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45633
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
hsa-miR-96	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12222
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157594_3_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:I20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04925
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CASK	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38798
TCFCP2L1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05461
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14972
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
into	GeneRIF Biological Term Annotations	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55623
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26462
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5303304-13073_2017_407_MOESM3_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S2_Genes_differentially_expressed_by_24h_RA_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27476975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31888
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.971552
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.737196
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.258
membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K16502264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0876
BRD-K48634117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45728
YWHAH	Pathway Commons Protein-Protein Interactions	1.0	null
spontaneous synaptic transmission	GO Biological Process Annotations 2023	1.0	null
BRD-K86817746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26349
Perturb_13057_Mut_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.82365
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18502
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.82465
regulation of regulated secretory pathway	GO Biological Process Annotations 2023	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15364
GSE87615_0_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.16782
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Edema	CTD Gene-Disease Associations	1.0	1.04501
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13894
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876883
BRD-K81522184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41064
CRCGN011_HEPG2_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13535
BRD-K37803976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03215
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01005
GSE137653_2_v_3_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.022
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-182	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
BRD-K71824916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38445
Prestwick-1080-3796	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61276
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69080049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39831
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94483
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14727
BRD-K63568016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04918
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55203
Perturb_12547_KO_Shank2_SRP309197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.13175
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50677
BRD-K67998155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70064
KMS-12-BM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14097
lithocholic acid-3816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39987
Perturb_4323_OE_Fos_SRP075838	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.992
Perturb_6501_KD_circSMO_SRP277579	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.3907
leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.36741
BRD-K68497273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33902
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K61595867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3547
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17744
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.706
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066363
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.938378
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6228
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44004
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07071
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10657376-41467_2023_43213_MOESM7_ESM.xlsx-DaNs_EBF1-Unnamed_6_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.09083
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44458
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14805
Deregulation of Rab and Rab effector genes in bladder cancer	WikiPathways Pathways 2024	1.0	null
BRD-K10180613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05465
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26729
vesicle organization	GO Biological Process Annotations 2015	1.0	null
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.884468
vesicles	GeneRIF Biological Term Annotations	1.0	null
DMRT1	ChEA Transcription Factor Targets	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95837
NZOV9	DepMap CRISPR Gene Dependency	1.0	2.4769
synaptic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887818
NCIH1693	DepMap CRISPR Gene Dependency	1.0	3.91332
Cardiac tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
Clathrin coat of coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03901
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Extrinsic component of mitochondrial outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.769
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.988
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55128
BRD-K96120749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82411
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23929
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1857
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33752
Perturb_15120_KD_LSD1_SRP331013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.27982
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_UPREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.736913
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37900095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08493
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31915
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94913508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.84181
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34876
nuclear outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170888
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0677
organic substance transport	GO Biological Process Annotations 2015	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
ZC4H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15633
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.774558
Clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
myosin	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K58955712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59733
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.428
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22874
dihydroergotamine-6840	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HIT-T15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3016
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-467-SP8_SP8	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.345754
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prestwick-1084-3546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.888925
some	GeneRIF Biological Term Annotations	1.0	null
BRD-A28153253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92699
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827067
A673	CCLE Cell Line Gene Expression Profiles	1.0	1.50206
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.08954
BRD-K16247913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32999
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heart_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.05337
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056758
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0988
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59359
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28915
ELK4-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K75724196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17244
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
BRD-K79402882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00949
Endocrine organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENTPD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54299
KYSE-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4510	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89631
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.919
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.532295
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2492
neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348889
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3114
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06433
BRD-A35323217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32761
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.43871
BRD-K55612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70566
BRD-K25917968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09536
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35801
BRD-K98089885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15596
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06383
ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.199325
hsa-miR-2681	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K47887272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39094
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-1.2464
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
BRD-A69950438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42507
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
0317956-0000-3969	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75319
BRD-K89325755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35322
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16281
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6822
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-KLF5_targets-target_gene_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
neurotransmitter secretion	GO Biological Process Annotations 2015	1.0	null
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6881
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5237
BRD-A20731954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47542
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57449
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23929
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	2.20634
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39878
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14201
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5876
present	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.42975
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45181
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72847
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11678
BRD-K66416915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6813
Scd1_DELETION_GDS4910_309_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_13975_KO_H3f3a_ERP109384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.20501
NOS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K10459843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31405
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.6261
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2025	1.0	null
forebrain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060173
BRD-K30013451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23317
Early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.483
Medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
Platelet Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66565
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844615
BRD-K64264170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51187
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61098
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82111
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
zinc ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K73841784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23991
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.129309
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68397
diseasehd	GeneRIF Biological Term Annotations	1.0	null
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Gata-4_KO_GDS4782_329_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5758
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256568
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943505
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63569
cholesterol, ldl	GAD Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16784
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04902
Zinc finger, RING/FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99134
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurons	Phosphosite Textmining Biological Term Annotations	1.0	null
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0679
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.379232
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55773
TEAD4	ChEA Transcription Factor Targets	1.0	null
extrinsic component of synaptic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31602570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38963
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9029
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855241
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78622
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826145
BRD-K98953112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43103
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
ciclacillin-3800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01888
S-propranolol-5444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.38298
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900151
D542MG	DepMap CRISPR Gene Dependency	1.0	2.04976
BRD-K20829034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05317
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12779
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5401
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
Urate levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06383
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
synaptic vesicle exocytosis	GO Biological Process Annotations 2015	1.0	null
BRD-K77417197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04375
Bone_Marrow-nampt neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	5.44898
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
NB7	DepMap CRISPR Gene Dependency	1.0	8.81339
Porosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42633
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0466
OPM2	DepMap CRISPR Gene Dependency	1.0	2.48579
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH446	CCLE Cell Line Gene Expression Profiles	1.0	1.75361
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61555339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10837
BRD-K29420358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68258
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03023
cellular process	GO Biological Process Annotations 2015	1.0	null
chromaffin granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.266408
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918517
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41016
HIF-2alpha_DEPLETION_GDS2760_643_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
zinc ion binding	GO Molecular Function Annotations 2025	1.0	null
frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Postsynaptic endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
synaptic vesicle	GO Cellular Component Annotations 2015	1.0	null
SLC35D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22101
hsa-miR-4642	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
fenbufen-2308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22292
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JW-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42403
TAL1	ENCODE Transcription Factor Targets	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
BRD-K02637547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53826
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7563
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A07214340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99971
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892768
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68512873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10929
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31791
AP-2 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
Integral component of postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04996
BRD-K73929798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37243
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.887
THRA	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-A84941884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27966
KP-N-YN	GDSC Cell Line Gene Expression Profiles	1.0	1.78803
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2481
ADD2	Pathway Commons Protein-Protein Interactions	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29153
pattern	GeneRIF Biological Term Annotations	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44825
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05884
cyclic-amp-dependent-protein-kinases	Phosphosite Textmining Biological Term Annotations	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16397
BRD-K56381552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72375
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.195353
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832691
Intracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.441
syntaxin binding	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A23345137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18367
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76646
Cell trailing edge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.0
Podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32182
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.60407
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
CRCGN017_MCF10A.TP53.M_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43845
NB10	DepMap CRISPR Gene Dependency	1.0	4.92498
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9589
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.692516
CAL120	DepMap CRISPR Gene Dependency	1.0	2.41229
ITPRIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6762
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98327
Alcohol consumption (max-drinks)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39964
BRD-K59272984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5138
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41544
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5591
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48448
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K54814515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11877
C7orf50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12608
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15882
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80336
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.884468
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_human_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142755
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37087
BRD-K77713205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37945
metabolic	GAD High Level Gene-Disease Associations	1.0	0.295739
colorectal	GeneRIF Biological Term Annotations	1.0	null
gtpase binding	GO Molecular Function Annotations 2015	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0929
exocytosis	GO Biological Process Annotations 2015	1.0	null
BRD-K56889360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53815
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	3.48839
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15747
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
organelle membrane fusion	GO Biological Process Annotations 2015	1.0	null
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40803
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.48325
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.2922
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86357
Clathrin coat of endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFO27	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.1581
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53187
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9097
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01003
GSE224157_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dorsal nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
SIN3A	ENCODE Transcription Factor Targets	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Griscelli syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.029
ca2	GeneRIF Biological Term Annotations	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3882
SCABER	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0647
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18478
BRD-K13873561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26035
chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.2708
rabphillin3alike	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8053
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.901147
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.904032
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.9552
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39071
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972097
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
gtpase	Phosphosite Textmining Biological Term Annotations	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03551
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365095
12747878-Table3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K98537764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18711
SKRC20	Achilles Cell Line Gene Essentiality Profiles	1.0	1.08019
ZCCHC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82731
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22599
LC1SQ	DepMap CRISPR Gene Dependency	1.0	5.01587
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
GMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30122
structural	GeneRIF Biological Term Annotations	1.0	null
EARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.988
decamethonium bromide-4174	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trans-synaptic protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31928
hand	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.848745
Synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.455
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ERBB2_knockdown_231_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66317
BRD-K43628610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49192
GSE211744_2_v_0_gdf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transition metal ion binding	GO Molecular Function Annotations 2025	1.0	null
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.138539
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98196
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0518
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
BRD-K27374902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29292
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Chloride Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40863
presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175188
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
establishment of synaptic vesicle localization	GO Biological Process Annotations 2015	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lipid traits (pleiotropy) (HIPO component 1)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24373
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61692
Neuronal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
BRD-K26026745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25396
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24335
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
VPS72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0063
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1003
Prestwick-685-6043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K54576503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69233
Craniopharyngioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.613
bacampicillin-4417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Rabphilin-3A	InterPro Predicted Protein Domain Annotations	1.0	null
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69734
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.866
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Myositis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
BRD-K90673570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50697
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K89320330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51915
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.146931
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3712
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7227
GSE249544,GSE249637_6_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28656917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04383
ZNF384	ENCODE Transcription Factor Targets	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60837711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11322
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0964
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12024
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.08701
orphenadrine-3801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
F36P	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47876
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
beta-escin-3807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2662-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08122
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6314
alcohol dependence	GWASdb SNP-Disease Associations	1.0	1.079
BRD-K88472400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22651
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1992
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02659
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942396
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89321
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
SLC66A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20206
Yolk granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coelomic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047483
GTF2F1_02_157	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.80735
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862212
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09523
SU-DHL-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BPH1	DepMap CRISPR Gene Dependency	1.0	4.20305
HUPT3	DepMap CRISPR Gene Dependency	1.0	3.40944
BRD-K22874335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75497
Nephrotic syndrome type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
POLR2J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49903
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.945112
single-organism membrane fusion	GO Biological Process Annotations 2015	1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.085563
MHH-NB-11	GDSC Cell Line Gene Expression Profiles	1.0	1.67436
BRD-K02050740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19453
EW-13	GDSC Cell Line Gene Expression Profiles	1.0	2.11054
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22132
TIMM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48042
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.976394
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33373
BRD-K70322385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22529
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905839
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12702
SKMEL28	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24224
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8425-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977814
NR2C2	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-501-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
BRD-K71419092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74774
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30823
SF1	MotifMap Predicted Transcription Factor Targets	1.0	null
extrinsic component of synaptic vesicle membrane	SynGO Synaptic Gene Annotations	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13715
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02673
calcium ion binding	GO Molecular Function Annotations 2023	1.0	null
PMC3271860__F3	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71419
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62703
SGS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07870648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64324
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984705
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51651
MAPKAPK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.45641
lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.648533
17761679-Table1	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A69648159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52601
hsa-miR-4725-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
neurotransmitter	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ER to Golgi transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.927
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0916
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14785
synaptic	Phosphosite Textmining Biological Term Annotations	1.0	null
Postsynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.843
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3014
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3407
BRD-K44167510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93039
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18405
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03214
BRD-K30643363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05992
BRD-K50058129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53423
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TU-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23115
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.657
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56851
BRD-K56354139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07506
single-organism process	GO Biological Process Annotations 2015	1.0	null
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4143
KELLY	CCLE Cell Line Gene Expression Profiles	1.0	1.89619
region	GeneRIF Biological Term Annotations	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31119
BRD-K43224838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12435
BRD-K67022703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06362
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43267
exocytic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956168
BRD-K93460493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24872
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42961
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2498
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05149
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.901816
tolmetin-4167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.899499
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
prasterone-6673	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44584
HDAC1	ENCODE Transcription Factor Targets	1.0	null
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC22A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12338
cation binding	GO Molecular Function Annotations 2015	1.0	null
Lewy body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
BRD-K07600484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36406
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20622
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.3292
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05784
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39237
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34049
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.963168
RAB27A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K52731958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.513
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94467
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21203
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
BRD-K16554464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31343
SLAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.287
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46569
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.849287
hsa-miR-4688	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K51461946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6028
non-syndromic X-linked intellectual disability 90	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.341
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
CAL120	Achilles Cell Line Gene Essentiality Profiles	1.0	1.27221
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
hsa-miR-3974	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO783	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.8293
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.43982
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14723
harman-2806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03212
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.63996
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4136_KD_Grin1_SRP106749	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.32356
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39372
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909423
Escherichia coli infection of the central nervous system_CNS - Brain (MMHCC)_GSE3253	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43239
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K20495487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03482
pi45p2	GeneRIF Biological Term Annotations	1.0	null
deficient	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9829
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53647
PTSD - Post-traumatic stress disorder_Peripheral blood mononuclear cell_GSE860	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.54432
CRCGN015_MCF10A_48H:G08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9255
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIVF001-028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3699
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.111649
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.18026
ChIP_TCFCP2L1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myasthenic Syndrome	DisGeNET Gene-Disease Associations	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45639
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28501
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19559
CRCGN011_HEPG2_24H:G17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3364
BRD-K31716785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2794
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20162
membrane part	GO Cellular Component Annotations 2015	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.3412
anion binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4700-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14221
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22353
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69961
cefotiam-2458	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67042874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45394
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10739
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
b-50 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487106
BRD-K32893898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.85815
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16265
chrysin-5505	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	2.18415
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61485947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19824
Germinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.015
motor	Phosphosite Textmining Biological Term Annotations	1.0	null
Autosomal dominant distal hereditary motor neuronopathy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.37
Serum Total Cholesterol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GCH1	Pathway Commons Protein-Protein Interactions	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29285
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.710909
boldine-2804	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18405
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CYP2U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05524
single-organism membrane organization	GO Biological Process Annotations 2015	1.0	null
trans-golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.169859
JUND	ENCODE Transcription Factor Targets	1.0	null
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31881
SF539	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.387
BRD-A16119053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94136
organelle part	GO Cellular Component Annotations 2015	1.0	null
Perturb_13976_KO_H3f3a/H3f3b_ERP109384	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.2979
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.673
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1363
BRD-K02334683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17615
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6978
camp	Phosphosite Textmining Biological Term Annotations	1.0	null
CAMK2A	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K78889331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20132
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00192
Congenital myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
extrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93736
GSE226249_5_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03452
CRCGN016_MCF10A.WT.HP_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48632
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal renal physiology	GWASdb SNP-Phenotype Associations	1.0	0.229355
synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
body	GeneRIF Biological Term Annotations	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.520041
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36988
Extrinsic component of organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.779
BRD-K57894545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19519
Adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.025
hsa-miR-630	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
grade	GeneRIF Biological Term Annotations	1.0	null
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09014
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20863
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
phosphatidylinositol phosphate binding	GO Molecular Function Annotations 2015	1.0	null
SSB_02_164	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
ZM-226600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52058
ZFHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40006
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13812
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K55286508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44887
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.99682
BRD-A08191729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39208
localization	GO Biological Process Annotations 2015	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39392
not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76058
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25121
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
etynodiol-6678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
plasma	Phosphosite Textmining Biological Term Annotations	1.0	null
Parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
COLO792	DepMap CRISPR Gene Dependency	1.0	2.29281
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11395
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03532
dacarbazine-4480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.91099
BRD-K93472147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15487
along	GeneRIF Biological Term Annotations	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3587
GSE195743_3_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12717
VPS4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
Chloride levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H11A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synaptic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SUB1_02_117	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.24793
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
BRD-A63704386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89394
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
COLO-792	GDSC Cell Line Gene Expression Profiles	1.0	3.1974
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59839
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
ETS1	ENCODE Transcription Factor Targets	1.0	null
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7174
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31482
BRD-K44121468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25501
C15orf40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.092
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.9201
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13359
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40564
skin	HPA Tissue Gene Expression Profiles	-1.0	-0.832797
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05461
BRD-K29903249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02634
hsa-miR-4747-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
Perturb_13054_OE_HDAC4_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306083
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CALM1	Hub Proteins Protein-Protein Interactions	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46055
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20207
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dantrolene-2369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4441	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K08927194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11821
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90295
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71026
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8447
Integral component of presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
BRD-K29218981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71021
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45584
BRD-K13164804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88592
BRD-K23535862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39133
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48035
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05015
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878801
PMC10311050-mmc2.pdf-43-PHOX2B_PHOX2B	Rummagene Transcription Factor Associations 2026	1.0	null
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21837
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neuron projection	GO Cellular Component Annotations 2015	1.0	null
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06141
BRD-K05050615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02652
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.0865
Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38621
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.50532
Movement Disorders	CTD Gene-Disease Associations	1.0	1.02708
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08455
hsa-miR-4738-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K37379978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3376
PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10011427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46766
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K51743001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56754
Brain germinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.602
BRD-K37961770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16681
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54781
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63007
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K59865704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04072
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A5W8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lbd	GeneRIF Biological Term Annotations	1.0	null
BRD-K81450614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01737
Ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.711
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.866384
concentrations	GeneRIF Biological Term Annotations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H5-01B-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
T-bar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.8
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
BRD-K12359218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48968
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.638434
BRD-K17259076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9357
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65005
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76829
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27608
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.878319
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.944634
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.673728
clathrin-coated endocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
BRD-A23980907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10891
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.112562
Abducens nerve palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35282
SIN3B	ChEA Transcription Factor Targets	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056137
hsa-miR-4419a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142755
HOS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13727
RNF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72687
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04321
GSE124410_3_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.203
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE108614,GSE108615_3_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20626
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12616242-can-24-3452_supplementary_table_s6_suppst6.xlsx-EWSR1FLI1-KDM6A-targets_down-EWSR1_FLI1-KDM6A_downregulated_targets_upon_KDM6A_knockout_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
OE19	CCLE Cell Line Gene CNV Profiles	1.0	1.35863
BRD-K82729862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3701
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
hsa-miR-502-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04557
Ovarian follicular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
Asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.67
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
BRD-A85216385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09275
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.890167
CRCGN009_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03826
Albuminuria	dbGAP Gene-Trait Associations	1.0	0.105922
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9282
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.960774
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11202
Chromaffin granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.528
MPP89	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9661
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.175992
Histiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
hit-t15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05985
GLIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64396
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99014
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
RAB3A	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65269
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12702
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.67658
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
MM1S	CCLE Cell Line Gene CNV Profiles	-1.0	-2.39853
primidone-3402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
GDF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86365
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
phosphate ion binding	GO Molecular Function Annotations 2023	1.0	null
PROB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65775
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70838
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypotonia-cystinuria syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29153
BRD-K82578220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83413
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.923279
Ionotropic glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.546
BRD-K41206520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1223
EFNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19332
kaempferol-3579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22607
RAB15	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of synaptic vesicle fusion to presynaptic active zone membrane	GO Biological Process Annotations 2025	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Platelet count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929676
SELENOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28984
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052329
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
calcium-dependent activation of synaptic vesicle fusion	GO Biological Process Annotations 2025	1.0	null
progesterone-6646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.01929
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.017
POLR2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45794
C8-MEF cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
Medial amygdalar nucleus, posterodorsal part, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03728
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10624
BRD-K71247208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22382
PMC12686523-41421_2025_842_MOESM6_ESM.xlsx-Table_S5-Supplementary_Table_S5_-_Target_genes_of_FOXG1_in_GBM_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20733942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11187
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37362
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.669037
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81053
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45488
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88638
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
bone marrow	HPA Tissue Gene Expression Profiles	1.0	0.983876
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36896
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60565
HCC-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
adaptor-proteins-vesicular-transport	Phosphosite Textmining Biological Term Annotations	1.0	null
rolitetracycline-5331	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69827
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16281
BRD-K90311252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37223
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03357
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1438
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054196
ipratropium bromide-5823	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8928
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.47717
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825193
telencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
OV7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.55262
Zinc finger, FYVE-related	InterPro Predicted Protein Domain Annotations	1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3807
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A77181042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10642
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907908
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
organelle fusion	GO Biological Process Annotations 2015	1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10550956-41467_2023_41912_MOESM4_ESM.xlsx-Supplementary_Data_8-Supplementary_Data_8_MR_and_colocalization_analysis_for_gene_expression_in_whole_blood_and_COVID-19_outcomes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Melanotroph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
H3K36me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANC0813	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22896
HHV8_72Hour-BEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.753
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PG-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955777
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	2.27172
embryonic	Phosphosite Textmining Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1977
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06724
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kinesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
iii	GeneRIF Biological Term Annotations	1.0	null
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2024
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27429
serotonin-5268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82264
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37303
synaptotagmin	GeneRIF Biological Term Annotations	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.923
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07721
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	2.17572
BRD-K73802986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07119
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934455
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.58661
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC6326667__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Spleen-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	1.77559
16728981-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.921199
alclometasone-6094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06278
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43714
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97037
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
metoclopramide-3728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
growth-&-development	Phosphosite Textmining Biological Term Annotations	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990357
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3023
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82094
TRMT112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26412
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.36011
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Psychoses, Substance-Induced	CTD Gene-Disease Associations	1.0	1.08091
BRD-K57096799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39544
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19211
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuron part	GO Cellular Component Annotations 2015	1.0	null
secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.922055
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09076
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	1.81004
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845824
SIRT6	ENCODE Transcription Factor Targets	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11892
BRD-K48782834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53963
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.80763
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.15089
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.63322
hsa-miR-675	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93927
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.43049
endomembrane system	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.400916
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
CRCGN014_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02432
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947717
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24362
SKNBE2	CCLE Cell Line Gene Expression Profiles	1.0	1.71424
BRD-K21982562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10826
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K55142307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06615
neurotransmitters	GeneRIF Biological Term Annotations	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.45521
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22275
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU61	DepMap CRISPR Gene Dependency	1.0	3.01202
CRCGN016_MCF10A.WT.HP_24H:K16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77582
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20359
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07333
chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.669657
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
HL60	Achilles Cell Line Gene Essentiality Profiles	1.0	3.1833
isopropamide iodide-2720	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAOV3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50205
melan-a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
BRD-K78009480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27014
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57599
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49446
exocytosis	GO Biological Process Annotations 2023	1.0	null
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4823
buspirone-5343	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K31030467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03963
GSE102269_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.258745
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21509
EZH2	ENCODE Transcription Factor Targets	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47351
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19183
BRD-K23196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96274
Perturb_16642_OE_Chmp2b_SRP238748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.77824
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26345
UBE3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27857
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.284371
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.153
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Early phagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.832797
KE97	CCLE Cell Line Gene CNV Profiles	1.0	1.34046
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41658
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
nefopam-3627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
synapse	GO Cellular Component Annotations 2015	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1996
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94467
parabigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH226	DepMap CRISPR Gene Dependency	1.0	2.04163
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2849
hsa-miR-4675	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.32488
spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37687
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.05721
GSE149035_7_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64949
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6804
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-2.54871
suggested	GeneRIF Biological Term Annotations	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.06223
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.191845
BRD-K90475322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77004
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9062
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13203
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959318
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
selenium binding	GO Molecular Function Annotations 2015	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885423
positive regulation of regulated secretory pathway	GO Biological Process Annotations 2025	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39991
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17245631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49198
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7487
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06391
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29951
secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.458006
BRD-K17176016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30089
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.13475
AR	ChEA Transcription Factor Targets	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18918
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97707
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76841
BRD-K31521981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42914
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17195
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LY75	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061047
Perturb_14667_KO_Sirt3_SRP277814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K87261428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03435
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9342
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.09401
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
clathrin-coated pit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
Neuromuscular junction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
cerebellum	Phosphosite Textmining Biological Term Annotations	1.0	null
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03098
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
Edema	CTD Gene-Disease Associations	1.0	1.35676
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885423
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45903
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7256
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PHA-00851261E-3776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
butirosin-6080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.656
biosynthesis	Phosphosite Textmining Biological Term Annotations	1.0	null
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67466
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Postsynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.4217
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.188292
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0442
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69827
BRD-K37780492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30455
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40171
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_10297_Mut|KO_Pkd1_SRP385932	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.3779
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2
BRD-K76166595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73172
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13048
GSE137653_4_v_0_siglecf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11563
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216126
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838524
NCIN87	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02247
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.86738
GI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32521
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Synaptic membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-A99687212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10166
Anteromedial nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47075
BRD-K53343197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68151
Neural lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
Rab-protein geranylgeranyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
TBP	ENCODE Transcription Factor Targets	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
BRD-K14207150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28582
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35385
Coated membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.574
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24761
Duodenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.37717
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.733319
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5557-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2613
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.857561
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886416
MLPH	Pathway Commons Protein-Protein Interactions	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
BRD-K90255725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19064
BRD-K33037101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41511
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49352
VAL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19733
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16549
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05677
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-5398-01A-02R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
capillary	GeneRIF Biological Term Annotations	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02057
BRD-K02783902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28245
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19487
BRD-K99971319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17548
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914578
PRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89043
BRD-K17751525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28478
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081616
snare binding	GO Molecular Function Annotations 2015	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
COQ10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36329
prostate_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0509
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15426
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48575
BRD-K25822126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16115
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03449
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042611
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92176
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
BRD-K39244231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7391
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5308
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84492
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of neutrophils	GWASdb SNP-Phenotype Associations	1.0	0.573037
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.675
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899906
COS-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
BRD-K44520987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.182
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
developmental	Phosphosite Textmining Biological Term Annotations	1.0	null
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
Dense core granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.977
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.840564
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04504
CTCF	ENCODE Transcription Factor Targets	1.0	null
Integral component of postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25098
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.582
BRD-K45010872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17396
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6875
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09468
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05461
aconitine-6797	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.91308
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.89194
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96699
insulin	Phosphosite Textmining Biological Term Annotations	1.0	null
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01882
subcellular	Phosphosite Textmining Biological Term Annotations	1.0	null
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56162
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00698
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40154
nitrofurantoin-2341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Peripheral artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
Synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Rab-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043856
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2247
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
hsa-miR-4650-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Parkinsonism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
neurotransmitter transport	GO Biological Process Annotations 2015	1.0	null
BRD-K76600600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32892
protein localization	GO Biological Process Annotations 2015	1.0	null
CCDC66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14681
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100102_0_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59041191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03069
secretion	Phosphosite Textmining Biological Term Annotations	1.0	null
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118125
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09303
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12023
CRCGN016_MCF10A.TP53.M_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72155
BRD-K09560946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6974
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899292
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Late endosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
BRD-K02337960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02053
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.9245
Dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
High Density Lipoprotein Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21503
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51255
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874712
diflorasone-4158	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	1.11189
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6176
BRD-K48994888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3597
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75102
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2519
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4811
RAB3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6547
sirolimus-362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K08141534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30981
BRD-K18211442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24973
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE249544,GSE249637_6_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.078712
neuronal	Phosphosite Textmining Biological Term Annotations	1.0	null
metal ion binding	GO Molecular Function Annotations 2025	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32933
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30772
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06292
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03076
BRD-K98841583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34588
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19136
BRD-K92650579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04432
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90761
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49881
Lung adenocarcinoma_LUAD_TCGA-44-2665-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medulla oblongata	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.074
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.854
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH23	DepMap CRISPR Gene Dependency	1.0	5.22651
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.88984
BRD-K54956860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0772
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071722
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919358
PMC11801220-NIHMS2038999-supplement-14.xlsx-Exc-MAF-gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27182
NCIH2291	DepMap CRISPR Gene Dependency	1.0	3.38653
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63539
Microvillus inclusion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955179
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18405
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868596
BRD-A64957606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11429
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.4986
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PDE6G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0047285
BRD-K27823380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69075
vesicles	Phosphosite Textmining Biological Term Annotations	1.0	null
Perturb_472_KD_ARAF_SRP259289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.6209
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93762
BRD-K90360779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22497
Synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4455
KAT2A	ENCODE Transcription Factor Targets	1.0	null
golgi apparatus	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94483
BRD-K74862734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0814
TP63	ChEA Transcription Factor Targets	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52377
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Extrinsic component of synaptic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K46805838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01987
BRD-K75576005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06343
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07227
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85923
difenidol-2374	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925821
phosphatidylinositol-4,5-bisphosphate binding	GO Molecular Function Annotations 2025	1.0	null
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02024
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13257
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9126
duodenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.871905
danazol-5315	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38755
BRD-K58336011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15845
Perturb_6177_KO_Bmal1_ERP113681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.5105
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844615
meclofenoxate-3707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-920	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4748
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22347
YWHAH	Hub Proteins Protein-Protein Interactions	1.0	null
Viral assembly intermediate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
HMOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22241
SFTPC_KO_GDS4876_476_mouse_Lung Type II cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Griscelli syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Neutrophils	dbGAP Gene-Trait Associations	1.0	0.05784
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21657
ADAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40509
single	GeneRIF Biological Term Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8001-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54616
Perturb_4321_KD_Cck_SRP220728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.27235
SubthalamicNucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.20512
SKMEL28	CCLE Cell Line Gene Expression Profiles	1.0	2.40509
hsa-miR-3184	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
synaptic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine system disease	GWASdb SNP-Disease Associations	1.0	0.152376
albuminuria	GAD Gene-Disease Associations	1.0	null
Cleft lip	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.313
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885423
PANC0504	DepMap CRISPR Gene Dependency	1.0	2.11622
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16171
MAPKAPK5	Kinase Library Serine Threonine Kinome Atlas	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31136
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16807
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.035
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921393
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
CRCGN016_MCF10A.WT.HP_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2028
BRD-K74040368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.05473
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.052805
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98117
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.683
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041691
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054664
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.621
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anterior group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15887
CRCGN015_MCF10A_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2365
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91456
Type IC spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
BRD-K88135858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83255
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59943
BRD-K89174739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27602
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.16339
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03503
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68202226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51436
BRD-K55638368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81144
BCPAP	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98485
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
CRCGN008_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0024
Necrosis	CTD Gene-Disease Associations	1.0	1.63832
EW-24	GDSC Cell Line Gene Expression Profiles	1.0	1.85085
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70905
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24839
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81446
Myosin VIII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
CHTF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76378
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.8245
BRD-K76654183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1456
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14764
BRD-K01182779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47157
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49126
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82967
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06482
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
F5	DepMap CRISPR Gene Dependency	1.0	2.14727
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55421
PHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03024
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
CRCGN017_MCF10A.TP53.M_24H:P07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24783
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844615
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26557
Perturb_14973_KO_Creb_SRP156780	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.36828
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11189
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22792
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00809
Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.52008
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996601
BRD-K44103530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53455
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
CEBPB	ENCODE Transcription Factor Targets	1.0	null
BRD-K05154886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15547
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864058
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05461
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37042
RS11846	BioGPS Cell Line Gene Expression Profiles	1.0	0.889932
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A5W6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A07195938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17487
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904491
cSARS Bat SRBD_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.40143
PIFO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8569
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
(-)-MK-801-6657	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874657
BRD-K06355852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14708
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839688
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.68756
Congenital disorder of glycosylation Ij	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70838
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4478
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0956
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876624
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8304
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32393
FAM219A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10645
BRD-K63188051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15374
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.662742
BRD-K16093370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58203
polymorphism	GeneRIF Biological Term Annotations	1.0	null
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.6
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65753
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11498
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053233
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuron projection	GO Cellular Component Annotations 2025	1.0	null
membrane fusion	GO Biological Process Annotations 2015	1.0	null
PRKACA	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K68257399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43661
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88002
hsa-miR-4668-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
SFTPC_KO_GSE35989_48_mouse_lung (type II cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
fluspirilene-3086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-gene_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bone_Marrow-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	1.55918
ANGMCSS	DepMap CRISPR Gene Dependency	1.0	2.82495
Terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.618
vesicle	GeneRIF Biological Term Annotations	1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K97487406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27759
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84144
BRD-K73330516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57911
Perturb_15081_KD_Crebbp_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.7055
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
kidney disease	GWASdb SNP-Disease Associations	1.0	0.735995
staining	GeneRIF Biological Term Annotations	1.0	null
fenoprofen-3714	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
blood	GTEx Tissue Gene Expression Profiles	1.0	1.20397
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
Adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.218
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60188481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46085
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24338
BRD-K40985311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18954
PMC6326667__F5	PFOCR Pathway Figure Associations 2023	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
secretion	GO Biological Process Annotations 2015	1.0	null
Systemic scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.892648
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.666402
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949274
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215341
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05461
GSE160293_2_v_4_celf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	0.920697
cytoplasmic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-V9-A7HT-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K17609687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30681
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HS742T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81053
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.3637
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41332
pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358546
BRD-K19161227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7883
BRD-K86232198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52988
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1992
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.907
hsa-miR-129-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
exocytosis	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-BNC2-gene_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36201
cell part	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4741	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02816
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.176024
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976223
NCIH2126	DepMap CRISPR Gene Dependency	1.0	5.49736
Amyotrophic lateral sclerosis type 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
Respiratory Function Tests	dbGAP Gene-Trait Associations	1.0	0.423158
Central diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.713
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Scleroderma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02659
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38417
hsa-miR-4719	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
positive regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2025	1.0	null
Cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03572
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31077
MZT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74508
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32828
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20558
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845566
regulation of transport	GO Biological Process Annotations 2015	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
cerebral hemisphere	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.400527
BRD-K63614330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1255
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969764
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067676
BRD-K19608763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38026
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61702
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Presynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7115
single-organism localization	GO Biological Process Annotations 2015	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950704
MAFK	ENCODE Transcription Factor Targets	1.0	null
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
phi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02659
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972725
Retinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.646145
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06262
PMC3271860__F3	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K11504077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50183
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
rab gtpase binding	GO Molecular Function Annotations 2015	1.0	null
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4909395-elife-13964-supp1.xlsx-Sheet1-Supplementary_file_1_shRNA_screen_hits_selective_to_ERG-positive_prostate_cancer_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40334
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
underlie	GeneRIF Biological Term Annotations	1.0	null
BRD-K35132745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32723
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918995
Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00909602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16747
CRCGN010_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01978
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.76041
BRD-K06611347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24117
Perturb_15225_KD_lncRNALFAR1_SRP101771	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Granulomatosis with polyangiitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
establishment of vesicle localization	GO Biological Process Annotations 2015	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15115
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13700_KD_HEPACAM2_SRP257754	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.27644
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17385
HSG	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.86452
regulation of neurotransmitter levels	GO Biological Process Annotations 2015	1.0	null
SHCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82966
nuclear membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.129444
FAM168B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6805
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27249
BRD-K53388755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29343
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8333
enzyme binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K31121304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15191
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35733
HIV encephalitis_frontal cortex_GSE3489	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.60239
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02822
medrysone-3603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055647
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
organelle organization	GO Biological Process Annotations 2015	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.1097
fibers	Phosphosite Textmining Biological Term Annotations	1.0	null
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.101188
hsa-miR-4726-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K34277236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26874
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.124
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31834
A673	GDSC Cell Line Gene Expression Profiles	1.0	1.58384
GSE149035_7_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88447
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
Pancreatic adenocarcinoma_PAAD_TCGA-F2-6880-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08172
BRD-K90356496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43598
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06966
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95709431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03722
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09495
BRD-K50829918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01349
Lymphoid leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
MMAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23527
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39717
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.293711
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23929
BRD-K63912037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06687
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9427
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18998
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27429
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	2.7439
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860117
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.653
regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
calcium- and calmodulin-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.162
exclusively	GeneRIF Biological Term Annotations	1.0	null
spontaneous neurotransmitter secretion	GO Biological Process Annotations 2023	1.0	null
IgG4-related disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
BRD-K88538240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10884
Parietal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
sulmazole-4127	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.895
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56468
substance dependence	GWASdb SNP-Disease Associations	1.0	0.301394
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78697404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56691
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
Prestwick-689-6076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4c-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03815
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960413
REST_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.495
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
oxedrine-6798	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23929
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53636
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93579
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2351
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K04462989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09085
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.698
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88542
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.014
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4043
BRD-K86966177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57633
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuron projection	GO Cellular Component Annotations 2023	1.0	null
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75051
colecalciferol-5002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.970686
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832539
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.832057
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Thalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.017
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23772
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58827489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00226
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081584
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16245
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843466
ID1_01_118	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59129
ELF5	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31194
BRD-K25426017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24364
naproxen-6096	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24562
Zymogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
BRD-A42536341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24124
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27352
modes	GeneRIF Biological Term Annotations	1.0	null
signal release	GO Biological Process Annotations 2015	1.0	null
FU-OV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3142
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77655
REST_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12554_Mut_Atxn1_SRP148491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43559
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16421
BRD-K95147720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39545
BRD-K20071915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32438
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73713
cone-rod dystrophy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1084
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4489
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854553
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.099358
neuroblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06976
BRD-K07762528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29355
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.63088
Nerve Growth Factor Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60485
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04695
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01888
positivity	GeneRIF Biological Term Annotations	1.0	null
BRD-K77797840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30073
Lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49826
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41943
A204	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48657
pheochromocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328262
Posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
BRD-K36104357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42877
HMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19741
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thiocolchicoside-5520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.94851
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12702
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0808
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.686
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11478
BRD-A40010674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75855
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97582
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25154
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0177
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93104
BRD-K04409515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01463
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27074
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
mouse	GeneRIF Biological Term Annotations	1.0	null
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K04918285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03311
Capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49992772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15557
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4493
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53439
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55097
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03036
hsa-miR-221	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17612
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.100672
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11202
flunixin-3713	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67178
Endolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4656	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3123
TE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10762
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6437
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37305
BRD-K24877937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48365
PMC7940623-41467_2021_21725_MOESM11_ESM.xlsx-Extended_data_table_9_regulons-POU4F1_extended_POU4F1	Rummagene Transcription Factor Associations 2026	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
hsa-miR-4640-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29738
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.191
BRD-K82784817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44706
BRD-K42964952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12125
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Syndromic X-linked intellectual disability Najm type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03439
fluocinonide-3933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01735
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07372
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96878
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SR	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67161
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.457
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872783
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50091
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
BRD-K91548063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98251
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30808
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81997160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20026
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.04735
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.26177
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06533
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62068620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70998
TPSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4343
cefmetazole-6086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.214
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66071
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.050421
immunology	Phosphosite Textmining Biological Term Annotations	1.0	null
hsa-miR-1910	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426109
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16549
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32418
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26680822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41986
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
transport	GO Biological Process Annotations 2015	1.0	null
BRD-K04562748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42756
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.57862
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61318
6-benzylaminopurine-3623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908189
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06278
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.891798
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.54901
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.41308
BRD-K15742845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61249
HOXC9	ChEA Transcription Factor Targets	1.0	null
BRD-K17175263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06209
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5933-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59258
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89819
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00409
huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.685891
atherosclerosis	GWASdb SNP-Disease Associations	1.0	0.729592
adenocarcinoma	GeneRIF Biological Term Annotations	1.0	null
Type II spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Muscular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41219
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	1.24612
CHD7	ENCODE Transcription Factor Targets	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phosphate ion binding	GO Molecular Function Annotations 2015	1.0	null
Adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.777
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DNM1	MSigDB Cancer Gene Co-expression Modules	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37305
BRD-K06451913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56382
SMC3	ENCODE Transcription Factor Targets	1.0	null
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23717
levonorgestrel-3606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anion binding	GO Molecular Function Annotations 2025	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1564
Langerhans-cell histiocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.633
PCSK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09343
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
calcium ion-dependent exocytosis of neurotransmitter	GO Biological Process Annotations 2015	1.0	null
BRD-K67905771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06832
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29121
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
glomerular	GeneRIF Biological Term Annotations	1.0	null
BRD-K50315405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10273
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0645
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09303
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hematopoietic system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.968503
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.54
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
P3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49542
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99894
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	2.03881
NCIH1869	DepMap CRISPR Gene Dependency	1.0	2.46892
Anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.768
UBB_KO_GDS3906_494_mouse_Testis -  21 Days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42883
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02416
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06462
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2802
RNF187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70543
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00662
Orofacial cleft	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.313
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827848
BRD-K79829201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27721
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12222
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.811891
ZR-75-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVISE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16245
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18503
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
BRD-A13082766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15761
NB14	GDSC Cell Line Gene Expression Profiles	1.0	2.2378
BRD-K25791914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36091
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
Syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.313
hydrocotarnine-2765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
BRD-K51163606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95761
respiratory function tests	GAD Gene-Disease Associations	1.0	null
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08388
brains	GeneRIF Biological Term Annotations	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.29599
BRD-K45361857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05014
TUBGCP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17338
BRD-K28349636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53115
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76235
MAZ	ENCODE Transcription Factor Targets	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K25081075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38794
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22792
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44026
Dentate granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
cimetidine-4063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K31852848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25351
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58161
BRD-K47028303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38117
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61494
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	1.0	1.31186
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00861
monastrol-311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67261
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29547381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14048
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56788
Perturb_15080_KD_Chd8_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.4338
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myopathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.861571
etacrynic acid-3181	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	2.18624
Vesicle tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.405
BRD-K07460436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08926
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23929
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
synaptic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
A4-FUK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30709
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.25853
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54537
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39987
ZNF263	ENCODE Transcription Factor Targets	1.0	null
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091608
GSE180951_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
REST_Panc1_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81660107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09997
Immune system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053342
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78311779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.61846
Thorny excrescence	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
BRD-K55852567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70764
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0851
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80553
small gtpase binding	GO Molecular Function Annotations 2015	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0255
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
insights	GeneRIF Biological Term Annotations	1.0	null
GSE111138,GSE111149_1_v_0_runx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB26	Pathway Commons Protein-Protein Interactions	1.0	null
secretion by cell	GO Biological Process Annotations 2015	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01735
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SUPT3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95663
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03025
RTRAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86635
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911162
NANOG-16518401-CHIP-PET-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ganglion	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.07
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.728836
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47094
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83704
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5224
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1734
LPS141	DepMap CRISPR Gene Dependency	1.0	2.81923
AMPA glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.448
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20558
JVM3	CCLE Cell Line Gene CNV Profiles	1.0	1.51514
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.886221
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fat-neutrophil	Tabula Sapiens Gene-Cell Associations	1.0	0.815622
BRD-K49847771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35359
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45825
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0625
Perturb_14796_OE_Mycn_SRP094656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.00108
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02004
BRD-K33151492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31596
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.261273
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G3-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217974
establishment of organelle localization	GO Biological Process Annotations 2015	1.0	null
abnormality of lipid metabolism	GWASdb SNP-Phenotype Associations	1.0	0.216234
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78083
Lewy Body Disease	DisGeNET Gene-Disease Associations	1.0	null
BRD-K40509138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34794
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.271
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03546
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.37708
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.817158
CRCGN016_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56023
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.371
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K87875370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56631
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58161
Acetolactate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
PC-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.162
chlorambucil-4345	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4c-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.3532
hsa-miR-1271	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_0_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1977
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.190495
BRD-K83189379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04397
Fertilization envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28547
NO10	DepMap CRISPR Gene Dependency	1.0	2.28996
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61364
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.424765
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952548
OVCAR4	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
MES-SA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1872
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.974473
EGI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.68144
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09509
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K80923834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22562
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959947
Perturb_8944_KO_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.10283
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02004
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833453
CRCGN016_MCF10A.TP53.M_24H:M14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67614
propidium iodide-6277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
clone9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
BRD-K47238978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05801
membrane organization	GO Biological Process Annotations 2015	1.0	null
Precerebellar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
Lymphocytic Neurohypophysitis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K42333498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64617
CRCGN011_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06345
SNU213	DepMap CRISPR Gene Dependency	1.0	2.02293
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4085
3-acetylcoumarin-5624	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88645
hsa-miR-423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07314
KANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17938
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	1.0	1.84447
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18235
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13203
Perturb_820_OE_Rspo1_SRP325709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ChIP_RCOR2_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K00620786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32022
remoxipride-3124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K72609445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34877
Griscelli syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52707
RNF113A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65834
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Contractile vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.609
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K60952519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47902
SUZ12	ChEA Transcription Factor Targets	1.0	null
Macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21882
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51608
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0948
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
symptoms	GeneRIF Biological Term Annotations	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383509
Lung adenocarcinoma_LUAD_TCGA-50-6595-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Membrane coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.58
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
Low Density Lipoprotein Cholesterol Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Coelomocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
Clathrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.52
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5675
BRD-K11571815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72544
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0509
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52889
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04877
BLK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646276
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18979
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.985
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
synaptic vesicle transport	GO Biological Process Annotations 2015	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.46906
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39421
Garland cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.935
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.483
Prestwick-1080-3878	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	3.47605
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949274
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98752
CACTIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05613
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40013
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
antibody-specificity	Phosphosite Textmining Biological Term Annotations	1.0	null
hsa-miR-4271	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
BRD-K94115999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60159
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.602
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39392
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054413
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.34155
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.835911
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.434985
GSS	DepMap CRISPR Gene Dependency	1.0	2.29998
Deregulation of Rab and Rab Effector Genes in Bladder Cancer(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
BRD-K86677819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1491
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
HUH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03901
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10243
nialamide-3790	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64736
Vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.405
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.945118
BRD-K84099887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02539
CRCGN015_MCF10A.WT.HP_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01819
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38621
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.48867
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00484
etilefrine-4415	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Presynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.94484
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09303
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Extrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
YAP1	ChEA Transcription Factor Targets	1.0	null
tyloxapol-4611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Integral component of synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0501
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893221
CRCGN015_HEPG2_48H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04295
roxarsone-5470	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050552
HCMV_TB40E_24Hour_19951172_GSE14816	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.22134
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2866
KURAMOCHI	GDSC Cell Line Gene Expression Profiles	-1.0	-2.16807
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12083
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60675
MYC	ENCODE Transcription Factor Targets	1.0	null
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44551
tinidazole-3813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18272
MG-63	GDSC Cell Line Gene Expression Profiles	-1.0	-2.39083
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
Ciliary necklace	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12702
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
synapse part	GO Cellular Component Annotations 2015	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01573
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227186
pc-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4827
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40137
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045201
Learning Disorders	CTD Gene-Disease Associations	1.0	1.53531
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86646
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845443
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.24619
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27618
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
BRD-K20798215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06644
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33467
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11208
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.383
BRD-K35124958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15898
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27429
chr12_112887655_T_C_b38	GTEx eQTL 2025	1.0	2.93035
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88189
prochlorperazine-6664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46378
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49004
Tetralogy Of Fallot	DisGeNET Gene-Disease Associations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MESP1_cust_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
NRSE	MotifMap Predicted Transcription Factor Targets	1.0	null
Idiosyncratic drug effect_Hepatic Tissue_GSE2825	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.25036
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10550956-41467_2023_41912_MOESM4_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_MR_and_colocalization_analysis_for_gene_expression_in_lung_and_COVID-19_outcomes_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058195
BRD-K46298577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40227
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35649
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.11098
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14201
SW-1088 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66079
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098885
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01273
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20691
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	1.05535
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06599
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07717
BRD-K98408574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70137
BRD-K69348766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09782
signal	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K01660763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11015
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14074
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7898
hsa-miR-338-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06887
flumethasone-pivalate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16372
secretory	Phosphosite Textmining Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49254
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1217
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2015	1.0	null
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166884
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892077
Cingulate gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.297
MCRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0649
NB6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27423
synaptic vesicle priming	SynGO Synaptic Gene Annotations	1.0	null
synaptic	GeneRIF Biological Term Annotations	1.0	null
BRD-K57969360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62532
Prestwick-691-4092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.293711
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone_mus musculus_gpl1261_gse11343	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
clonidine-6814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967322
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35666
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23187
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.345754
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.784
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular transport	GO Biological Process Annotations 2015	1.0	null
BRD-K70940767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00031
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84604
adrenal gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25882
BRD-K45537529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32602
Buccal mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
BRD-K43654313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26475
Perturb_13876_OE_ABCC1_SRP301382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_AD1-STAT3_target_genes_predicted_by_CHIP-seq_overlap_with_genes_in_AD_M1_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172845
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852445
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42803
enzyme-inhibitors	Phosphosite Textmining Biological Term Annotations	1.0	null
Disruption of postsynaptic signaling by CNV	WikiPathways Pathways 2024	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORVET complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50443
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38621
protein transport	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02405
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060778
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.593
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59841546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19555
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRCGN017_MCF10A.TP53.M_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26043
TNFRSF25	MSigDB Cancer Gene Co-expression Modules	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7167-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41498330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24966
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20463
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.624
Type 2 diabetes mellitus_Muscle tissue_GSE12643	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66126
Perturb_6500_KD_circSMO_SRP277579	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CRCGN017_MCF10A.WT.HP_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1266
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21522
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50901
female	Phosphosite Textmining Biological Term Annotations	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054504
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CAS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72002
PMC11554977-40199_2024_523_MOESM2_ESM.xlsx-Sheet1-Supplement_2_Metformin_Drug_Sensitivity_and_Damaging_Mutation_by_using_PRISM_Repurposing_Primary_Screen_and_Damaging_Mutation_in_DepMap_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0023
Albumen gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
SKNAS	CCLE Cell Line Gene CNV Profiles	1.0	1.73712
Weibel-Palade body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.067
BRD-K22584556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16664
protein binding	GO Molecular Function Annotations 2015	1.0	null
SW872	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00474
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	1.47556
MYC	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07823
BRD-K47410882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56393
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.27687
BRD-K63858518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32367
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916196
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13439
DIFI	DepMap CRISPR Gene Dependency	1.0	2.67464
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1986
Autosomal genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
STAT3	ChEA Transcription Factor Targets	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214765
BRD-K73830970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32584
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32247
arm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.78938
COLO677	CCLE Cell Line Gene Expression Profiles	1.0	1.5222
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARS CoV_54Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.31114
NCIH520	CCLE Cell Line Gene Expression Profiles	-1.0	-2.48996
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
secretory granule	GO Cellular Component Annotations 2015	1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5769
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78465
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.11604
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64422
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13882
OCUM1	DepMap CRISPR Gene Dependency	1.0	3.3368
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85437
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04634
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17947
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7975
B-50 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36171309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93121
15750623-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
BRD-K15280583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05064
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06208
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06192
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
Intrinsic component of postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
Field CA2, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16772
BRD-K87023633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08277
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01314849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99854
ketoprofen-4286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MELHO	CCLE Cell Line Gene Expression Profiles	1.0	1.43459
EW-3	GDSC Cell Line Gene Expression Profiles	1.0	1.79383
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17217
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08998
Golgi apparatus subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.513
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
suloctidil-6675	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.833
BRD-K96733881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13781
MM1S	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.61627
betaamyloid	GeneRIF Biological Term Annotations	1.0	null
OC314	DepMap CRISPR Gene Dependency	1.0	4.78286
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5794192-ppat.1006868.s001.xlsx-S1B_Table-S1B_Table_Differentially_expressed_genes_between_IRF8-sg2_and_NC_cell_lines_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
Pulmonary Edema	CTD Gene-Disease Associations	1.0	1.12634
BRD-K07982814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01091
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29812
pancreatic	Phosphosite Textmining Biological Term Annotations	1.0	null
KARPAS-45	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58187
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH889	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56613
calcium ion binding	GO Molecular Function Annotations 2025	1.0	null
BRD-K17675523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31178
Poisoning	CTD Gene-Disease Associations	1.0	1.29348
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53770426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01842
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
zoxazolamine-6290	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lewy	GeneRIF Biological Term Annotations	1.0	null
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60485
BRD-K82019575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1878
Primary motor area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04504
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985371
regulation of vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2023	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10928
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41836
Uropod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.018
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42344
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MHHES1	CCLE Cell Line Gene Expression Profiles	1.0	1.44746
Presynaptic periactive zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Eye degenerative disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
MIN-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
JHESOAD1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.3487
Granum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.357
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29606
Dynactin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85088
PMC12041165-401_2025_2886_MOESM1_ESM.xlsx-Meta_CAA_vs_AD-Genes_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52129
STAT1	ENCODE Transcription Factor Targets	1.0	null
transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.381969
SETDB1	ChEA Transcription Factor Targets	1.0	null
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.635572
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866377
PMC12184553-JAH3-14-e039451-s001.pdf-28-ZNF184_ZNF184	Rummagene Transcription Factor Associations 2026	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-0.832797
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69827
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.34424
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.145
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.446439
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.89
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41668
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.934227
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0925
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97992
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0758
hsa-miR-1182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
0179445-0000-3733	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6998
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.756
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83425
synaptic vesicle exocytosis	GO Biological Process Annotations 2025	1.0	null
COMMD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02276
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F4-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.35
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4733
Neuromuscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0679
pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47896
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89326
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1694	CCLE Cell Line Gene Expression Profiles	1.0	2.94515
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959983
Leukemia	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
BRD-K35422614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04629
Prefrontal cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.467
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99134
GSE96991,GSE97117_3_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.92447
ca2+	Phosphosite Textmining Biological Term Annotations	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.826104
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259929
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07158
BRD-K60052521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0373
BRD-K45519638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23935
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.301394
BRD-K65441343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26334
Acute Myeloid Leukemia_LAML_TCGA-AB-2813-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
Glutamatergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.376
abnormality of the upper urinary tract	GWASdb SNP-Phenotype Associations	1.0	0.126983
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.649
Perturb_100_KD_Pabpn1_SRP318863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.58214
orlistat-6383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LRP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22642
GSE116492,GSE116495_3_v_1_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
exocytosis	GeneRIF Biological Term Annotations	1.0	null
phosphatidylinositol bisphosphate binding	GO Molecular Function Annotations 2015	1.0	null
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83054
GAL3ST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25309
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041378
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50219
LRP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03564
RCC10RGB	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.03932
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920059
Cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.44
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3524
BRD-K84541452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82831
Degeneration of macula and posterior pole	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
ciclopirox-6677	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12702
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23937
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.711
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
hsa-miR-4667-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.833
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05605
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10437
ZNF578	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29749
BRD-K26273412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11485
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.851
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.75501
Presynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.554
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06733
BRD-K19526797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16901
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32366
trichostatin A-364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08159
CRCGN010_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11184
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-106a-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873739
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.11675
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06966
BRD-K29898553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16932
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12553
Cerebral gyrus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.297
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05864
Low HDL-cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
Perturb_4056_KO_Rest_SRP260102	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.96232
NH-12	GDSC Cell Line Gene Expression Profiles	1.0	2.25982
BRD-K26461918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61326
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2481
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2023	1.0	null
Glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.281
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.07267
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052491
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04123
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13036
cellular component organization	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981627
SOX2	ChEA Transcription Factor Targets	1.0	null
hormone	Phosphosite Textmining Biological Term Annotations	1.0	null
exisulind-314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0929
melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.661208
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12222
cattle	Phosphosite Textmining Biological Term Annotations	1.0	null
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.906364
sgs cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.791044
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.59114
BRD-K45342423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43657
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19192
PRKD1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
CRCGN013_HEPG2_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06209
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.734323
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39246
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ADNP_Deficiency - NULL MUTATION_GDS2540_691_mouse_E9 embryos - Heterozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
carbachol-3380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.42429
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75145
BRD-K09720842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35341
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20558
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86594
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060774
Neuronal dense core vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.943
BRD-K13267677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26096
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.887133
phosphatidylinositol bisphosphate binding	GO Molecular Function Annotations 2025	1.0	null
Rheumatic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
Distal axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.723
COLO792	CCLE Cell Line Gene Expression Profiles	1.0	1.65416
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
alphasynuclein	GeneRIF Biological Term Annotations	1.0	null
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10243
Perturb_14122_KD_Tcf4_SRP061034	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCD_KO_GSE24243_46_mouse_Skin (8-9 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
rat	GeneRIF Biological Term Annotations	1.0	null
BRD-K60936953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30457
alcohol abuse	GWASdb SNP-Disease Associations	1.0	1.079
sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09402
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.313
synapses	Phosphosite Textmining Biological Term Annotations	1.0	null
BRD-K19225848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35776
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09128
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.053045
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55928
neutrophils	GAD Gene-Disease Associations	1.0	null
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20319
effector	Phosphosite Textmining Biological Term Annotations	1.0	null
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20947
CRCGN016_MCF10A.TP53.M_24H:N24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17103
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1568	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
presynaptic	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Endoplasmic reticulum exit site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
BRD-K64567246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77199
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990763
aging	Phosphosite Textmining Biological Term Annotations	1.0	null
PA-TU-8988T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02659
docking	GeneRIF Biological Term Annotations	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06595
Hypothalamic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.860117
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydroxyzine-6660	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56702
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08238
Brain Diseases	CTD Gene-Disease Associations	1.0	1.22727
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80135
BRD-A92357389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36937
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10354
PRKACA	KEA Substrates of Kinases	1.0	null
Lymphatic system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15528
KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79556
BRD-A63590986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53341
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Clathrin coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.551
Autosomal dominant disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14206
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985445
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
Warburg micro syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39313
pka	Phosphosite Textmining Biological Term Annotations	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27415
BRD-K04701596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14108
2-PMDQ	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11025
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045489
hsa-miR-3153	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Mild cognitive impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052712
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40906
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.51669
BRD-K27719710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29603
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02395
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
KDM5B	ENCODE Transcription Factor Targets	1.0	null
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34168
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EEF2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55683
Age related macular degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.884
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876851
BRD-K73688688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02135
Pheochromocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-DAY1_SOX17_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61437
NCIH2122	DepMap CRISPR Gene Dependency	1.0	3.55039
BRD-K89194869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13949
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15123
wall	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900901
Perturb_6393_KO_Ngr1_SRP098816	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.55392
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.35
Martsolf syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.931
dense core granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.28409
methoxsalen-6661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K54495109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7538
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98354
nefopam-3730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10401
Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Apolipoprotein B levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
CSTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19146
parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13796
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cerebral cortex	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01772
Exocytic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
TC71	CCLE Cell Line Gene CNV Profiles	-1.0	-2.47204
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32762
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67218
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.591
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
GCHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46432
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1905
BRD-K39688447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75962
BRD-K83919473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18688
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10657707-jad-96-jad230559-s005.xlsx-Sheet1-degree_of_nodes_in_PPI_network_for_MI_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27147269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03898
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28175
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BH-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6199_KO_Elp3_SRP065804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.41199
KELLY	DepMap CRISPR Gene Dependency	1.0	2.73659
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23569
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16245
BRD-K75688032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0987
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058886
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
BRD-K14875480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20944
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90028
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76871
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064565
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0088
TFCP2L1	ChEA Transcription Factor Targets	1.0	null
BRD-K22510845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73595
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47197
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920787
propylthiouracil-4076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26637
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
mt3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
Postsynaptic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.673
prostate_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
MedullaOblongata	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06705
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947079
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11272
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72317
phosphatidylinositol binding	GO Molecular Function Annotations 2015	1.0	null
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76988
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20622
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inositol 1,4,5 trisphosphate binding	GO Molecular Function Annotations 2025	1.0	null
BRD-K60127720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43536
BRD-K41829399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43171
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30382953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22697
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMS10	CCLE Cell Line Gene CNV Profiles	1.0	3.26414
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8863
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.983594
podocyte	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87686
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15634
PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835324
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09538
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824849
Neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
PMC12700546-jci-135-197583-s034.xlsx-ST18-Unnamed_2_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K90806964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51138
Hematologic cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K29143088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29085
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.42214
phosphatidylinositol bisphosphate binding	GO Molecular Function Annotations 2023	1.0	null
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
hsa-miR-499-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
ACTR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16943
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917402
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.39921
timolol-5645	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
neurotransmitter secretion	GO Biological Process Annotations 2023	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.214714
COLO320	DepMap CRISPR Gene Dependency	1.0	4.17358
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88365
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.37389
neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.42922
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27435
sk-n-sh cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24804
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04836
BRD-K58534227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29223
Central Diabetes Insipidus	DisGeNET Gene-Disease Associations	1.0	null
LRRK2_mutant_32_GDS4400	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.74716
REST	ENCODE Transcription Factor Targets	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.27292
SW837	GDSC Cell Line Gene Expression Profiles	-1.0	-1.73686
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K22069962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1268
Lip disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.313
synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.195025
Neuron to neuron synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.666
OVCAR3	BioGPS Cell Line Gene Expression Profiles	1.0	0.856851
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.095746
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93496
LOUCY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	1.39101
hsa-miR-1266	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29694
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874046
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056776
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pituitary cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11938
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2835
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100762
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94687
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14554
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.76849
A-CA-04-2009(H1N1)_Day1_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.71352
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3057
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12523
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
regulation of secretion	GO Biological Process Annotations 2015	1.0	null
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93589
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00319
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08524
all	GWASdb SNP-Phenotype Associations	1.0	0.053591
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56803
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843466
rats-sprague-dawley	Phosphosite Textmining Biological Term Annotations	1.0	null
NB1643	DepMap CRISPR Gene Dependency	1.0	3.67444
renal insufficiency	GWASdb SNP-Phenotype Associations	1.0	0.562717
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916659
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hippocampal mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.598
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.736913
hsa-miR-484	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
synaptic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
BCL3	ChEA Transcription Factor Targets	1.0	null
thiamazole-3815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
phosphatidylinositol-4,5-bisphosphate binding	GO Molecular Function Annotations 2015	1.0	null
H2AK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
extrinsic component of synaptic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
ras gtpase binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88096
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38487
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40354
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14403
fusion	GeneRIF Biological Term Annotations	1.0	null
SNUC1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.48565
NCI-H441	GDSC Cell Line Gene Expression Profiles	-1.0	-2.29568
transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.968884
PMC8945049__F4	PFOCR Pathway Figure Associations 2024	1.0	null
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5052
BRD-K50603336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94968
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.555
RUNX2	ChEA Transcription Factor Targets	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56749
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21271
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
finger	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.849585
transmitter	GeneRIF Biological Term Annotations	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05004
MIAPACA2	DepMap CRISPR Gene Dependency	1.0	2.23952
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916659
SW756	DepMap CRISPR Gene Dependency	1.0	2.1611
BRD-K11589884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15896
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
phenelzine-3802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
ciclacillin-4358	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	1.35119
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68B-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol-2701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
propoxycaine-3583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
procarbazine-3533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59943
ramipril-3572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4455
BRD-K90003650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10203
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34846
Acute Myeloid Leukemia_LAML_TCGA-AB-2916-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPARC_Deficiency_GDS3636_524_mouse_Lens epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75866
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
potassium	Phosphosite Textmining Biological Term Annotations	1.0	null
Myelencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.074
myosmine-4759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.46891
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28298
BRD-K32063762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05728
artery disease	GWASdb SNP-Disease Associations	1.0	0.333049
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867007
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886416
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37252
inositol 1,4,5 trisphosphate binding	GO Molecular Function Annotations 2015	1.0	null
Transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RAB3D	Pathway Commons Protein-Protein Interactions	1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38782
BRD-K18562847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7505
BRD-K78119702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62548
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32031
BRD-K37062347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11878
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.631598
CRCGN015_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80289
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8666
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44584
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.889
BRD-K19089958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03398
pargyline-7016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30424
ADD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08307
organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K72519034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28941
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24235529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13024
Pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50325
BRD-K34423419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35171
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17532
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03051
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF154	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0998
CRCGN015_MCF10A.TP53.M_24H:M24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06925
PMC12205070-41467_2025_61222_MOESM5_ESM.xlsx-DE_markers_TAL1_scenic_reductio-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85554
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12238
Perturb_13928_OE_DLG2_ERP119345	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BRD-K17979415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91523
BRD-K68605096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12996
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20209
temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K09711841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89648
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991775
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70412800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1504
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77965
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20863
adaptor-proteins-signal-transducing	Phosphosite Textmining Biological Term Annotations	1.0	null
erbB-2_OE_GDS1925_164_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
kidneys	GeneRIF Biological Term Annotations	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915757
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01064
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.046
Huntington's Disease_Brain_GSE3621	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.55127
CRCGN015_MCF10A.TP53.M_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03319
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15011
BRD-K55927371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1717
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886574
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7128-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19515
BRD-K30312557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19028
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9088
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cam	Phosphosite Textmining Biological Term Annotations	1.0	null
exocytic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.348
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11892
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01872
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11128
NCIH716	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12216
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56929
Brain Lower Grade Glioma_LGG_TCGA-DB-5270-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16421
TRIM46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16939
BRD-K55392659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05011
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
proxyphylline-5993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6047
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1734
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06383
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.82993
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856106
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08126
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60717
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8264
COPII-coated ER to Golgi transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.954
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71635
ZNF219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82668
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24775
imidurea-5481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
calcium-calmodulin-dependent-protein-kinases	Phosphosite Textmining Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29879
untranslated	GeneRIF Biological Term Annotations	1.0	null
PIK3CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506183
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32897
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058128
disease	GWASdb SNP-Disease Associations	1.0	0.068973
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PAX7	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K06398048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15788
BRD-A67787745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80267
huntington	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-2278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15698
BRD-K32195266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58376
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2031
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60065
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2543
OCUM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K57388326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50891
BRD-K77343050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08044
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06007
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.539417
SNU1272	CCLE Cell Line Gene Expression Profiles	-1.0	-2.80977
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.870217
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7918
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
Hypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.652
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.258064
respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177576
Axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.693
Oligospermia	CTD Gene-Disease Associations	1.0	1.27813
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07647
BRD-K25328765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70223
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03484
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.00399
TN2	DepMap CRISPR Gene Dependency	1.0	2.15148
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29735
BRD-K18268126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9957
BRD-K38788176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00865
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48301
nerve-tissue-proteins	Phosphosite Textmining Biological Term Annotations	1.0	null
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01872
KP-N-YS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53731
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29359
FREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10327
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09616
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2346
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9927
immune	GAD High Level Gene-Disease Associations	1.0	0.293278
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16925
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46257
Prestwick-691-4172	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K75772626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01291
BRD-K80109782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1429
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2258
Exocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38461
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06964
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
progesterone-2426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K07534805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18382
altizide-4491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-REST_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16938
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Growth cone filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.04036
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.903665
cortical granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.677673
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18427
BRD-K99807388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20986
hypertension	GWASdb SNP-Disease Associations	1.0	1.4233
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	1.92749
Perturb_15747_KO_Cnga1_SRP327351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.1901
PCI-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Contractile vacuole complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Fasciolar gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067143
BRD-K73095160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16779
BRD-A26165232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99343
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00256
suramin sodium-7496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.905105
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12634
mebeverine-3193	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KP2	DepMap CRISPR Gene Dependency	1.0	3.90201
entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227186
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05658
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838141
SKMEL2	CCLE Cell Line Gene Expression Profiles	1.0	1.37292
BRD-K02809100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13274
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9091
RCOR3	ChEA Transcription Factor Targets	1.0	null
thyroid gland disease	GWASdb SNP-Disease Associations	1.0	0.735995
UTP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11912
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell projection	GO Cellular Component Annotations 2015	1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
NR2F2_01_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59401
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28775
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6752
Lambert-Eaton myasthenic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
CRCGN015_MCF10A.WT.HP_24H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93482
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8196
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.099358
CRCGN017_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19685
hsa-miR-4724-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34918
riboflavin-2760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trimethadione-4165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14446
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
SKNSH	CCLE Cell Line Gene Expression Profiles	1.0	1.6611
BRD-K61432982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45634
PodNet: protein-protein interactions in the podocyte(Mus musculus)	WikiPathways Pathways 2014	1.0	null
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56209
Cortical granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.849
NCI-H345	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51285
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52377
cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81052
SNU46	CCLE Cell Line Gene Expression Profiles	-1.0	-2.4759
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60687
DMAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0292
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887302
Uric Acid Measurement (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A20182314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66775
TMEM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37538
BRD-K27476515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04625
SRSF4_02_154	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.90689
BRD-A78085235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33511
Neurotransmitter receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.577
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97215
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.405305
FOXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74386
BRD-K37219127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0562
Sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06767
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68315
Intrinsic component of synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.74102
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.2752
chloroplast part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066338
Perturb_13059_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.2596
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
BRD-K47620421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60266
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03302
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
TCFCP2L1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
BRD-K51608472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31831
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10825
inositol 1,4,5 trisphosphate binding	GO Molecular Function Annotations 2023	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851127
Synaptic vesicle, recycling pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LHX1_LHX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07540687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14127
LAN2	DepMap CRISPR Gene Dependency	1.0	4.73456
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67163
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
2,6-dimethylpiperidine-3889	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
participates	GeneRIF Biological Term Annotations	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44868
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10085
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95344
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19802
Agranular insular area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14201
BRD-K70289438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35129
XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus)	WikiPathways Pathways 2014	1.0	null
lovastatin-2854	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191539
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
REST_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00707
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55885
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65692
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52184
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A_48H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10052
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22427
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0504
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99134
ethaverine-3375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
INS-1E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24609
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1185
phosphatidylinositol-4,5-bisphosphate binding	GO Molecular Function Annotations 2023	1.0	null
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19807
SMG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55098
abnormality of cholesterol metabolism	GWASdb SNP-Phenotype Associations	1.0	0.382498
BRD-K53199675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68417
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6585_KO_Clpp_SRP114840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.26072
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11202
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06364
vidarabine-2706	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35015
glucose	Phosphosite Textmining Biological Term Annotations	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23929
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59943
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58483
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zinc finger, FYVE/PHD-type	InterPro Predicted Protein Domain Annotations	1.0	null
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241132
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464948
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41561
CRCGN015_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90835
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22792
BRD-K09699976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50726
BRD-A97759891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38247
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_15224_KD_lncRNALFAR1_SRP101771	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K54198678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62222
PTCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36076
BRD-K82683018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22021
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81019
NRSF	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01735
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6175
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05678
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REST_Panc1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amphotericin B-6303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057798
BRD-A06578049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0569
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00256
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47542
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7372
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990046
regulation of localization	GO Biological Process Annotations 2015	1.0	null
KP2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.85762
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00567
JUN	ENCODE Transcription Factor Targets	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56468
BRD-K46970272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73333
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21051792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22336
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22001
UACC257	CCLE Cell Line Gene CNV Profiles	1.0	2.19354
KM12	CCLE Cell Line Gene CNV Profiles	1.0	1.47152
coronary artery disease	GWASdb SNP-Disease Associations	1.0	1.20667
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.963
AKIRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23497
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43137
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.0177
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886416
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39987
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
EW-18	GDSC Cell Line Gene Expression Profiles	1.0	1.50318
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182375
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58138
severity	GeneRIF Biological Term Annotations	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74569
capsaicin-3372	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tetracaine-7473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02149
HT29	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.40657
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16811
drofenine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51143
viral infectious disease	GWASdb SNP-Disease Associations	1.0	0.217537
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6526
MPZL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66267
BRD-K69453385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13957
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K97236134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45884
BRD-K03015524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16663
LAN-6	GDSC Cell Line Gene Expression Profiles	1.0	1.51708
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.193162
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.36252
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K57251296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09588
BRD-K75821161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06062
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862887
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
transition metal ion binding	GO Molecular Function Annotations 2015	1.0	null
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.319619
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.936
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37718
ERR2 (ESRRB)	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04109
BRD-K10189430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25086
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26441
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01455
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.946626
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.367
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45358
cyclothiazide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36531
Perturb_8943_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.7712
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3518
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52329
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95941120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22007
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal degeneration	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.972
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC11263679-41598_2024_66946_MOESM1_ESM.pdf-101-ZNF281_ZNF281	Rummagene Transcription Factor Associations 2026	1.0	null
EPHB2_drugactivation_228_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.71711
BRD-K89719122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42676
Perturb_6636_KO_SATB1_ERP024525	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.9884
SKMEL2	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
NCIH1836	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71903
TET1	ChEA Transcription Factor Targets	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830897
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K40276277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51425