association dataset threshold value standardized value MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01525 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.956689 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PTPN6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25968 Scoliosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 GTEX-QDVJ-0626-SM-48U1T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.907652 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LT-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.736471 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DKMG CCLE Cell Line Gene CNV Profiles -1.0 -2.12265 BB-79-AG41_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.808267 eGFP-JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 2 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36252 SRF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BAT3 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.378 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DHX33 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4612 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3627 STAT3 ENCODE Transcription Factor Targets 1.0 null 15474998-tableS1c GeneSigDB Published Gene Signatures 1.0 null GTEX-S4UY-0526-SM-3K2AN GTEx Tissue Sample Gene Expression Profiles 1.0 1.69595 GSE166315_1_v_4_docetaxel_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WFG8-0008-SM-4LVN6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04993 u138mg HPA Cell Line Gene Expression Profiles -1.0 -1.75797 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null Colon - Sigmoid GTEx Tissue Gene Expression Profiles 2023 1.0 5.48526 GTEX-XMK1-2526-SM-4B666 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12641 S0-EE-YEKU_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.303452 supraoptic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.869661 CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40268 GSE139455_2_v_3_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WL46-0626-SM-3LK7R GTEx Tissue Sample Gene Expression Profiles 1.0 1.82143 Lateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07802 PD-70-VS77_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.4495 EF-74-KW12_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -5.47466 CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMEL31 CCLE Cell Line Gene Expression Profiles -1.0 -1.60402 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZN-2126-SM-4DXU1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.832137 SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.929137 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04155 GSE205332_1_v_0_queuine_human RummaGEO Drug Perturbation Signatures 1.0 null outer SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.986176 a549 HPA Cell Line Gene Expression Profiles 1.0 1.25177 KLF13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.4488 PMC11947124-41419_2025_7562_MOESM1_ESM.docx-348-ENSG00000066827_ZFAT Rummagene Transcription Factor Associations 2026 1.0 null r9 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63205 GSE86507,GSE86509_7_v_8_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null GPR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38277 DC-23-UM36_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.736673 SIRT6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HC-92-HE59_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.789315 SRF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null S0-EE-Y4UM_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.43531 Perturb_6031_KD_LOXL1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 intermediate stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28945 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.32058 AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5WG-1926-SM-4KKZK GTEx Tissue Sample Gene Expression Profiles 1.0 2.7509 H3K9ac_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34229 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.65449 GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.866863 GTEX-P44H-0326-SM-2XCES GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846434 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4EP-0826-SM-3P5YK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1538 GSE213588_10_v_0_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-105 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE231891_1_v_0_cdk8_human RummaGEO Gene Perturbation Signatures 1.0 null SLC25A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19187 H3K36me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64726 GSE211151_1_v_0_progesterone_human RummaGEO Drug Perturbation Signatures 1.0 null upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.91304 CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LD-39-FL02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.219386 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null ND-15-RC31_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.339727 r9 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25664 2793_EXOSC6_P1P2 Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures 1.0 1.03559 mantle zone of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2117 GTEX-OHPM-1626-SM-2HMK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.49789 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.866578 GSE193258,GSE193259_9_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures -1.0 null H3K79me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null liminal part of the r7 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23044 7671_SBNO2_P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.566696 EIF2B4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69131 GTEX-RTLS-0008-SM-48FET GTEx Tissue Sample Gene Expression Profiles 1.0 0.877992 POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleic acid binding GO Molecular Function Annotations 2015 1.0 null primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.10676 PC-62-AQ92_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.626818 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.35633 GSE158320,GSE183351_0_v_3_lin28b_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-R55G-2326-SM-2TC61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.85947 H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-0426-SM-2I5F5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08386 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27806 Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AF-67-LZ82_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.642239 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles 1.0 1.46111 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.838144 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25815 Grm TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.621 dorsal terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04907 POLR2A_K562_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles 1.0 2.01861 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17732 superficial stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24532 GTEX-TKQ1-1226-SM-4GICJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.859807 U138MG CCLE Cell Line Gene Expression Profiles -1.0 -1.70093 ATF2 ENCODE Transcription Factor Targets 1.0 null PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC Rummagene Transcription Factor Associations 2026 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null 496100651_FWM_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.58548 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79864 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55456 H3K79me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.43981 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NRF1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-2467-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25664 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.45919 TYK2_knockdown_176_GSE44652 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.97569 Adipose - Subcutaneous GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.746306 Cardiovascular system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.8 Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49835 BE-81-QL64_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.92456 8666_TAF5_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.71647 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49622 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A642-01A-12R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EB-67-WB79_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.565176 Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null NCIH1651 CCLE Cell Line Gene CNV Profiles 1.0 2.14943 GSE167546_1_v_2_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CF-87-AS90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.94981 E2F6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TFAP2A-35110662-HEPM-HUMAN-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null EE-03-SG02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.228568 KDM1A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Jiyoye TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.175 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Primary B cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.56499 r10 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18918 MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.42204 GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19833 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00247 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GNL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16021 SCC9 CCLE Cell Line Gene Expression Profiles 1.0 2.94117 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE159678_4_v_3_chloroquine_human RummaGEO Drug Perturbation Signatures 1.0 null FD-62-ZB67_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.887696 MDAMB361 CCLE Cell Line Gene CNV Profiles 1.0 1.90621 RD-90-OY66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.53791 TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE109140_0_v_3_valproic acid_human RummaGEO Drug Perturbation Signatures -1.0 null CB-99-OG76_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.948591 POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE139455_0_v_3_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null mantle zone of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88903 H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WFON-0526-SM-4LVLY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.89649 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.83658 5888_NUP155_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.633126 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRCA1 ENCODE Transcription Factor Targets 1.0 null GTEX-SIU8-0426-SM-4BRUE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22558 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.28642 ER membrane insertion complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.165 UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 TAF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NF-21-HQ00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.32853 NCI-H1573 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.96834 CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null blood vessel GTEx Tissue Gene Expression Profiles -1.0 -1.98079 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.6367 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.868905 GTEX-X5EB-1826-SM-4E3K8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19163 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61687 GTEX-OXRN-1326-SM-3LK5V GTEx Tissue Sample Gene Expression Profiles 1.0 1.92928 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15916 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-QV44-0526-SM-2S1RE GTEx Tissue Sample Gene Expression Profiles 1.0 0.985076 G-361 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.662 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.977337 C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.2842 AA-22-UI44_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.600352 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 H3K36me3_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.852014 FOXM1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU5 CCLE Cell Line Gene CNV Profiles -1.0 -1.78671 6870_PSMD2_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.511695 Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0426-SM-4B66A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14764 FA-63-WI26_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.20235 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NELFE_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 449_ARFGEF2_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.619593 GTEX-T8EM-0326-SM-3DB7F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.874319 endoribonuclease complex GO Cellular Component Annotations 2023 1.0 null ARC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17186 LUDLU1 CCLE Cell Line Gene Expression Profiles 1.0 2.54951 H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NFIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8197 HC-01-FD24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.219753 AE-13-CX28_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.27791 5659_NGDN_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.530791 TTC21B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05233 LMO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40003 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE166004_7_v_0_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE206270_2_v_0_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles 1.0 0.879336 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE160077,GSE160084_2_v_0_bin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null DA-35-DU85_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.656521 BA-84-WN26_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.18085 GTEX-OHPN-0011-R3A-SM-2I5FC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.862597 LUDLU1 CCLE Cell Line Gene CNV Profiles 1.0 2.59792 H3K27ac_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100422_TCx_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.08713 FOXA1_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12866_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GLMN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58443 SMG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02036 EA-18-FP00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.856283 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67538 GSE226439,GSE226441_6_v_2_hnf4g_human RummaGEO Gene Perturbation Signatures -1.0 null GSE208350_4_v_1_fgfr1_human RummaGEO Gene Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 8691_TARBP2_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.542119 HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null 3537_GRINA_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 1.25553 medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01553 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-0626-SM-3NMA6 GTEx Tissue Sample Gene Expression Profiles 1.0 2.57535 GTEX-XYKS-2426-SM-4AT43 GTEx Tissue Sample Gene Expression Profiles 1.0 1.96691 ZBTB32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30896 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EL-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE206270_1_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKCO1 CCLE Cell Line Gene CNV Profiles 1.0 1.33274 NCIH854 CCLE Cell Line Gene Expression Profiles 1.0 1.70974 Lung squamous cell carcinoma_LUSC_TCGA-37-4135-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ECGI10 CCLE Cell Line Gene CNV Profiles 1.0 1.35152 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH889 CCLE Cell Line Gene CNV Profiles 1.0 1.35062 primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.83204 stratum pyramidale of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.936228 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TML8-1326-SM-4DXTO GTEx Tissue Sample Gene Expression Profiles 1.0 1.0958 Malpighian tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.518 TUBE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8325 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.63065 KP-1N Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.79489 GTEX-SN8G-0126-SM-32PLI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829802 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SP1 ENCODE Transcription Factor Targets 1.0 null GTEX-OIZH-0926-SM-48TBR GTEx Tissue Sample Gene Expression Profiles 1.0 0.845868 PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Viral cardiomyopathy_Myocardial tissue_GSE4172 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.53426 GTEX-UJHI-1726-SM-3DB9B GTEx Tissue Sample Gene Expression Profiles 1.0 2.15446 GSE157383_6_v_1_abemaciclib_human RummaGEO Drug Perturbation Signatures -1.0 null MYC_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TYK2_knockdown_35_GDS4754 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.97569 membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.850161 Duodenum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.182 PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_6021_KD_HNRNPA2B1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 6581_POT1_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures -1.0 -0.571158 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles 1.0 1.81515 GTEX-PW2O-1926-SM-2S1OB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44416 JJ012 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.884034 POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25815 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR Rummagene Transcription Factor Associations 2026 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.36997 FA-36-VA24_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.728384 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPD_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null sin3a_22783022_mcf7_lof_human_gpl570_gds4388 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.624862 TCF7 ChEA Transcription Factor Targets 1.0 null SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null poly(a) rna binding GO Molecular Function Annotations 2015 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE216043_7_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RUSQ-1926-SM-2TF6K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06665 AE-39-DG66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.713529 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Culmen Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02132 H3K9ac_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.93361 GSE150055_0_v_1_melphalan_human RummaGEO Drug Perturbation Signatures 1.0 null u251mg HPA Cell Line Gene Expression Profiles -1.0 -0.982924 Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.61667 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.896471 VA-48-RJ44_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.893099 MYC-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Atrophy CTD Gene-Disease Associations 1.0 1.08266 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.865633 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GB-57-XV52_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.685667 POLR2A_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.92664 SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.81391 DF-00-BU08_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.320098 Nucleoli CM4AI U2OS Cell Map Protein Localization Assemblies 1.0 null cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.87747 CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.89568 GTEX-UPJH-0526-SM-4IHK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.41461 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSB-1826-SM-3TW8M GTEx Tissue Sample Gene Expression Profiles 1.0 0.961257 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.88938 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13709 CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles 1.0 1.18144 KLRG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14366 GTEX-R55E-1126-SM-48FDZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13413 RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BB-20-UU03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.925505 H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ChIP_H3K36me3_18692474_mouseESC ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WOFM-1726-SM-3MJFA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5646 GTEX-XQ3S-0926-SM-4BOPI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.956682 GTEX-XQ3S-1126-SM-4BOPK GTEx Tissue Sample Gene Expression Profiles 1.0 0.869515 PROX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1721 internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93582 FOS ENCODE Transcription Factor Targets 1.0 null PMC11109217-41420_2024_2017_MOESM3_ESM.xlsx-Fig_4H_TAF2-bound_genes-Tag_dentsity_of_TBP_ChIP-seq_signal_for_TAF2-bound_genes_in_Fig_4H_TBP Rummagene Transcription Factor Associations 2026 1.0 null SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849129 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25815 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4308 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 dorsal cochlear nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.846162 cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5605 primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839707 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 organelle LOCATE Predicted Protein Localization Annotations 1.0 null EC-62-OE64_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.63489 CEBPD ENCODE Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HB-06-WU12_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.61756 CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NE-94-VE83_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.47304 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.70122 QE-79-XO29_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.443636 H3K4me1_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UNC5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.83447 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.67463 GTEX-QVUS-0008-SM-447AY GTEx Tissue Sample Gene Expression Profiles 1.0 0.996023 GSE148252_5_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NE-34-OZ69_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.274458 GTEx Breast 20-29 vs 60-69 GTEx Tissue-Specific Aging Signatures -1.0 -3.95995 GSE139455_4_v_5_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null Subthalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3489 r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2395 SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KATOIII_STOMACH CCLE Cell Line Proteomics 1.0 6.29107 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null STAT1 ENCODE Transcription Factor Targets 1.0 null muscle GTEx Tissue Gene Expression Profiles 1.0 2.18427 CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TFAP2A ENCODE Transcription Factor Targets 1.0 null CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12848_KO_Kdm4a_SRP192379 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.66744 Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26274 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.825091 GSE154219_0_v_2_cholestyramine_mouse RummaGEO Drug Perturbation Signatures 1.0 null CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.83367 intermediate stratum of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68868 CTCFL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.948 medial part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36614 orbital frontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.975487 BC-15-EL49_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.584906 superficial stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20762 HS 294T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00518 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CREB3L4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6339 trochlear nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.0889 P3H4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.73438 Lung adenocarcinoma_LUAD_TCGA-49-4506-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196540,GSE196542_2_v_5_dnmt3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null inner CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.884256 AA-23-FM46_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.392269 PLAGL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10313 SKM1 CCLE Cell Line Gene Expression Profiles 1.0 1.41664 H3K27ac_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KA-29-AB08_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.69645 Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.6126 GSE142430_2_v_1_prmt5_human RummaGEO Gene Perturbation Signatures -1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.3335 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.92794 GSE133213_11_v_3_znrf3_mouse RummaGEO Gene Perturbation Signatures 1.0 null WC-16-IR43_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.291343 RPLP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24216 GTEX-U8T8-0326-SM-3DB93 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42588 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null gdm1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.072 TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC Rummagene Transcription Factor Associations 2026 1.0 null RNAse mitochondrial RNA processing (MRP) complex CM4AI U2OS Cell Map Protein Localization Assemblies 1.0 null GTEX-WYBS-0426-SM-3NM9M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65715 TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFATC1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Rheumatoid arthritis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 AD-16-HL96_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.31324 H3K79me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AB-18-YN11_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.46829 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4756-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 HD-51-KD29_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.25299 H3K36me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOT4-0426-SM-4B66T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09371 RAD21_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BC-14-CG34_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.681433 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KARPAS-1106P Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21153 parahippocampal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.980688 SRP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22266 ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969178 TBP_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCFL ENCODE Transcription Factor Targets 1.0 null H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE216274,GSE216292_4_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mono-Mac-6 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.554 MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null WB-48-EF24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.672519 CTCF_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FE-10-KQ78_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.227942 cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.54425 molecular_function GO Molecular Function Annotations 2015 1.0 null GSE127790_10_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null CD4_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.02035 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE227592_8_v_1_adar_human RummaGEO Gene Perturbation Signatures 1.0 null lateral part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69131 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88368 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45383 GTEX-P44H-0226-SM-2XCEU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14346 ME-31-RM40_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.890918 H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bone structure disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 H3K4me1_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PBX3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-1326-SM-4LVN3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879192 hek293 HPA Cell Line Gene Expression Profiles 1.0 1.01856 superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49279 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04083 Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01286 PML_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AD-18-XC14_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.873898 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5O9-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA-68-KG29_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.82087 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11982_KD_E2F1_SRP109107 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.31418 H3K36me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65356 EFM-192C Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.47888 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5258 GB-57-XV52_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.340619 AA-58-FJ71_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.69123 LXF-289 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877261 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.25731 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850031 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XUW1-0726-SM-4BOP5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49272 MYC-19079543-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRO-0011-R9A-SM-3NB1X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.134 TCF7L2_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.903089 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles 1.0 0.845428 Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FB-66-UU47_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.255516 CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5903287-NIHMS956886-supplement-Table_2.xls-THP1_THP2_cds_exp_down-gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null HCT-116 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.73964 PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null BB-20-UU03_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.429935 GSE232714_0_v_1_raver1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QCQG-0226-SM-48U28 GTEx Tissue Sample Gene Expression Profiles 1.0 0.849578 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZG-0326-SM-47JXN GTEx Tissue Sample Gene Expression Profiles 1.0 2.1262 REST_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE226285_3_v_0_glutathione_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K79me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RUNX2-24655370-MC3T3E1-MOUSE-BONE ChEA Transcription Factor Targets 2022 1.0 null POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null AC-74-ZA35_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.873775 superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17692 GTEX-R3RS-0008-SM-48FF1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18818 cellular_component GO Cellular Component Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20819 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31367 lymphnode_5b HPA Tissue Sample Gene Expression Profiles 1.0 0.861606 inner SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.877663 H4K5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CC-03-PW00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.415251 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.14763 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A1-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mammillary body, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.41346 JD-62-HR05_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.39042 H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null AA-62-HP31_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.316568 Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65044 GTEX-V955-2626-SM-3NM9F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13642 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9771 GF-57-LR72_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.203701 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5881-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTPBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29837 TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AC-31-PL89_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.301173 Brain - Cerebellar Hemisphere GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.899337 BCL3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IA-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of ZIC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05429 Lung squamous cell carcinoma_LUSC_TCGA-66-2794-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62246 H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CE-96-GH46_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.569995 BB-86-BE19_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.88084 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70672 CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PB-09-OE00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.337165 TF-04-RX73_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.719883 SPI1-20176806-THIOMACROPHAGE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHOS-3 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -6.69209 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.979758 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3451-01A-02R-1188-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15636 CTCF_WI38_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HC-74-HM63_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.474822 H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE149264,GSE149267_4_v_5_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null KLE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01323 OE-31-YC41_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.940047 parasolitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04878 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWN1-1626-SM-2S1OL GTEx Tissue Sample Gene Expression Profiles 1.0 0.862378 GTEX-N7MS-0426-SM-2YUN6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31326 GTEX-XUJ4-0326-SM-4BOP9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38245 chr9_34615803_A_G_b38 GTEx eQTL 2025 1.0 4.39324 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.851121 GSE200673,GSE200691_1_v_3_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null EXOSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27838 PD-70-VS77_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.665853 TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 NCI-H69 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -1.97408 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53964 H3K36me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00632 GTEX-T5JW-0008-SM-4DM5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.22823 GA-59-RW04_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.16683 rna binding GO Molecular Function Annotations 2015 1.0 null MTF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11138 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.937809 GSE200673,GSE200691_1_v_0_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null 5470_NAT10_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.574184 NCI-H1651 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.13213 r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62133 YY1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE62843,GSE64371_2_v_3_furan_mouse RummaGEO Drug Perturbation Signatures -1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08389 KLF4 JASPAR Predicted Transcription Factor Targets 1.0 null COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.18288 SCLC-21H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.56512 11235_NON-TARGETING_NON-TARGETING Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.532735 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.22774 dorsal subdivision of VLC Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23263 GTEX-OHPN-2726-SM-2I5H4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27321 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SCC9 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.954296 SP4 ENCODE Transcription Factor Targets 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22049 REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16121 SKNAS_AUTONOMIC_GANGLIA CCLE Cell Line Proteomics 1.0 3.441 Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE206093,GSE206094_1_v_3_isl1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RAD21_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20653 Lung adenocarcinoma_LUAD_TCGA-05-4389-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE142210_3_v_7_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles 1.0 1.72319 Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.48708 496100507_FWM_dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.30164 KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE224131_3_v_1_mafb_human RummaGEO Gene Perturbation Signatures 1.0 null GTF2F1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE167886_3_v_1_chd7_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null medial intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.894756 zona incerta complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05363 CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE127790_6_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RU1J-0326-SM-46MUM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19163 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5238 RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12865_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PML ENCODE Transcription Factor Targets 1.0 null IRS2_KO_GDS1219_304_mouse_brown preadipocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-0526-SM-2XCBC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23006 Spinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 FD-62-ZB67_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.85771 hsa-miR-1321 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 4371_KIAA1958_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.500581 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles 1.0 1.96705 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPVG-2526-SM-4B66D GTEx Tissue Sample Gene Expression Profiles 1.0 2.45404 SPSB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07346 RELA_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PVOW-0726-SM-2XCF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -3.24409 CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 5657_NFYB_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.539335 CTCF_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Z8-2026-SM-3K2A9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14605 heart muscle HPA Tissue Gene Expression Profiles 1.0 1.1315 WM-115 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.605 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AE-13-CX28_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.752477 CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18059 POLR2A_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0426-SM-3GIJI GTEx Tissue Sample Gene Expression Profiles 1.0 1.08248 SMAD1-26771354-MESC-MOUSE-STEM ChEA Transcription Factor Targets 2022 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5892_KD_CBX1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.1157 H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4758-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 hsa-miR-129-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.670641 SRF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NE-94-VE83_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.823331 GSE57871_1_v_10_vorinostat_human RummaGEO Drug Perturbation Signatures -1.0 null membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 FOXA2_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34986 GSE146982_7_v_1_gpd1_human RummaGEO Gene Perturbation Signatures 1.0 null TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58752 Nucleolus COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.545 GSE148252_1_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null KLF1 ChEA Transcription Factor Targets 1.0 null doxorubicin_homo sapiens_gpl10558_gse42531 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null FE-29-XM40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.36284 NUMBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18853 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null E2F6_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.02555 intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.899471 Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05936 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.965244 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832158 GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16226 GTEX-TKQ1-1426-SM-4GICK GTEx Tissue Sample Gene Expression Profiles 1.0 1.47608 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45256 H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06568 GTEX-XXEK-0726-SM-4BRWF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14927 1536_CFL1_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 1.02445 CAL-39 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.77896 GTEX-P4QT-1526-SM-3NMCT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.868849 GSE125782_0_v_1_glutamine_mouse RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE218879_1_v_2_acetaminophen_mouse RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.34239 GTEX-WXYG-2526-SM-3NB3F GTEx Tissue Sample Gene Expression Profiles 1.0 2.57369 GSE226249_5_v_3_pirfenidone_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40153 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.917043 NCIH2347 CCLE Cell Line Gene CNV Profiles -1.0 -1.33404 GSE221327_6_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null VEZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8658 Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Corpus cardiacum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.994457 H2AFZ ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01514 POLR2A_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07566 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70402 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.943799 PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 22RV1 CCLE Cell Line Gene Expression Profiles 1.0 1.62041 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EGR1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HC-74-HM63_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.80323 Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02787 layer 4 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0105 Prostate adenocarcinoma_PRAD_TCGA-G9-6369-01A-21R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211286_1_v_5_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S95S-0008-SM-4AT5M GTEx Tissue Sample Gene Expression Profiles 1.0 0.930377 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.91771 superficial stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31439 POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC3371315-NIHMS350140-supplement-12.xls-MCF7-T47D-SK-453_Down_Common_xl-Supplementary_Table_5_Luminal_Signature_Genes_decreased_in_all_four_cell_lines_MCF7_T47D_MB-453_SKBR3_with_knockdown_of_FOXA1_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71376 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82461 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Proboscis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.56 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TD-29-IN36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.46074 GSE203308_14_v_0_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 SW948_LARGE_INTESTINE CCLE Cell Line Proteomics 1.0 2.46493 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BA-68-FJ41_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.402068 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.5659 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.11453 Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GE-53-SM76_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.26995 primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.90115 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.04875 GTEX-RU72-1226-SM-2TF6N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.903317 GSE165548_2_v_1_gemcitabine_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null vomeralnasalorgan.VMO. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.00874 lateral part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06497 GTEX-SN8G-0526-SM-32PLE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59052 HCC1897 CCLE Cell Line Gene CNV Profiles 1.0 1.42507 cell part GO Cellular Component Annotations 2015 1.0 null GSE81803,GSE81912_0_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null DD-65-SA37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -5.85038 GSE148252_5_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_11654_KD_MCFP_SRP113334 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.73629 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32932 CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA ChEA Transcription Factor Targets 2022 1.0 null CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12955 r9 part of the lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15916 REST_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6653 r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63697 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36685 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QCQG-2126-SM-2S1P8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07105 Perturb_13802_KO_Mettl14_SRP286301 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20685 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null GSE104022_1_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null CXXC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05005 cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85844 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNA polymerase III complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.536 PMC4944136-srep28995-s2.xls-DPRX-gene_DPRX Rummagene Transcription Factor Associations 2026 1.0 null r5 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04353 BACH1 ENCODE Transcription Factor Targets 1.0 null NCIH716 CCLE Cell Line Gene Expression Profiles 1.0 1.87698 H3K79me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null outer SZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88354 GTEX-OOBK-0008-SM-3NB27 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17059 GTEX-PLZ5-0326-SM-3P614 GTEx Tissue Sample Gene Expression Profiles 1.0 0.882011 MDA-MB-361 COSMIC Cell Line Gene CNV Profiles 1.0 2.59653 OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21153 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67538 H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30408 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE197555_0_v_2_trametinib_human RummaGEO Drug Perturbation Signatures -1.0 null Ovariole TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.526 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32973 JA-79-II25_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.251451 tegmental field of p3 (Forel's field) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54246 GTEX-VUSG-2826-SM-4KKZM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.86766 lateral part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43247 Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE150215_1_v_2_etl4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE219195_1_v_2_rbm12_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UPJH-0926-SM-4IHKA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.985542 Perturb_6014_KD_FUS_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 6555_POLR3A_P1P2 Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures 1.0 1.02187 H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PIP4K2C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1106 RAD21_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12 ENCODE Transcription Factor Targets 1.0 null RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1162 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.975735 PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE146687_2_v_0_eribulin_human RummaGEO Drug Perturbation Signatures -1.0 null Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73363 FE-56-PV35_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.2575 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47T-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BB-79-AG41_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.02779 EB-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null nucleus of the central acoustic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09157 PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35714 TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7585942-mmc4.xlsx-RBM10_KD-Unnamed_3_AR Rummagene Transcription Factor Associations 2026 1.0 null JC-06-ED36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.69527 PML_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU886 CCLE Cell Line Gene Expression Profiles -1.0 -1.89665 DE-48-HZ49_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.212999 Right_Atrium Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.85564 RET_druginhibition_184_GSE49414 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.03146 LC1SQSF CCLE Cell Line Gene CNV Profiles 1.0 1.54132 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.917 DA-07-LL18_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.264288 USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.36051 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.10282 CTCF_WI38_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.907031 Perturb_3486_KO_Mettl3_SRP273291 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85695 ctv1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.925 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63314 HS-SULTAN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04283 Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79647 GTEX-U8XE-1026-SM-4E3HM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955093 PB-09-OE00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.289291 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null r8 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16836 AA-22-UI44_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.738273 GSE234340_1_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_6072_KD_SUMO2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE138945,GSE138947_0_v_1_mboat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null 496100347_PCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.16807 MORCPR CCLE Cell Line Gene Expression Profiles 1.0 1.68863 LB373-MEL-D Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.20758 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Idiopathic scoliosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.34 TFAP2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 144.991 PLAG1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 97.4444 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QXCU-0006-SM-2TC5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43452 hMPV_48Hour_18234263_GSE8961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.40085 GTEX-RWSA-0126-SM-2XCBB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25926 H3K9ac_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PCBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.46584 CBX3 ENCODE Transcription Factor Targets 1.0 null CDK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.14294 GTEX-PSDG-0426-SM-2S1OF GTEx Tissue Sample Gene Expression Profiles 1.0 0.919845 Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.78759 GTEX-T6MN-0008-SM-4DM7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.960993 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.70772 SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.86087 GTEX-TKQ2-1026-SM-33HB7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67399 EIF2AK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03987 GSE157594_6_v_7_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null PAX6 ChEA Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.33593 GTEX-PLZ6-0008-SM-48TD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.3903 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.68534 CTCF_A549_hg19_10 ENCODE Transcription Factor Binding Site Profiles 1.0 null JURLMK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.38085 SKMEL1 CCLE Cell Line Gene Expression Profiles -1.0 -1.73436 hsa-miR-1470 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-Q2AI-0926-SM-48U1F GTEx Tissue Sample Gene Expression Profiles 1.0 0.957068 ELK1-22589737-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CUX1 ChEA Transcription Factor Targets 1.0 null H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WRHK-1726-SM-3MJFK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20168 TSPYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12386 MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN74 CCLE Cell Line Gene Expression Profiles 1.0 1.4211 GSE146982_7_v_6_gpd1_human RummaGEO Gene Perturbation Signatures 1.0 null nicotine_myzus persicae_gpl9470_gse18658 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-T8EM-1626-SM-3DB7K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00497 prostate HPA Tissue Protein Expression Profiles 1.0 0.776627 GSE149264,GSE149267_4_v_3_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ND-39-PO34_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.52396 GTEX-U4B1-0226-SM-4DXU8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03258 CEBPB ENCODE Transcription Factor Targets 1.0 null GSE112761,GSE112767_2_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures 1.0 null A704 CCLE Cell Line Gene CNV Profiles -1.0 -1.39952 Lymph node TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.1 BC-54-ON71_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.207893 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTF2E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2398 GSE148252_7_v_6_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QV44-0008-SM-447AX GTEx Tissue Sample Gene Expression Profiles 1.0 1.0232 Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHK1_KD_GSE54268_666_human_MCF-10A GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.973245 CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS2_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-1126-SM-3NM93 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22883 CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null AE-95-UU45_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.605202 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02434 CF-24-KQ98_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.21005 MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-46-3768-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.57342 CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWN1-0008-SM-48TEA GTEx Tissue Sample Gene Expression Profiles 1.0 0.965967 MARVELD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.95215 inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01362 GTEX-WFG7-2326-SM-3GIKV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14317 GSE160077,GSE160084_3_v_0_bin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AP5B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.004 Htk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.794 ZNF75D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7794 LF-94-HB11_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.364455 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.6333 YY1 ENCODE Transcription Factor Targets 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.902822 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WK11-2526-SM-3NM9Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.11564 GTEX-PVOW-0008-SM-48TE8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06948 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46741 ficolin-1-rich granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.013 ZNF343 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.8999 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CL-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.865171 GSE213228_1_v_5_irak2_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UJHI-1126-SM-4IHLN GTEx Tissue Sample Gene Expression Profiles 1.0 1.17982 H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TT Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.71377 GSE168797_4_v_6_cannabidiol_human RummaGEO Drug Perturbation Signatures -1.0 null WM793B Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -4.06233 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OXRL-1626-SM-2YUMU GTEx Tissue Sample Gene Expression Profiles 1.0 1.98766 GSE213588_10_v_6_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null USPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86245 GTEX-P4QS-1626-SM-2S1NH GTEx Tissue Sample Gene Expression Profiles 1.0 1.41295 GTEX-POYW-0526-SM-2XCEY GTEx Tissue Sample Gene Expression Profiles 1.0 1.25385 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BE-31-XV38_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.634823 Lung adenocarcinoma_LUAD_TCGA-50-5068-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MTRFR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05816 GTEX-O5YT-0926-SM-48TDG GTEx Tissue Sample Gene Expression Profiles 1.0 0.905733 Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80013 GSE114883_0_v_2_romidepsin_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43224 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.932357 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.1752 NUDHL1 CCLE Cell Line Gene CNV Profiles 1.0 1.4567 CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO3 ChEA Transcription Factor Targets 1.0 null H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE203329_0_v_1_mettl5_human RummaGEO Gene Perturbation Signatures -1.0 null GSE167004_0_v_3_thpo_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PX3G-1626-SM-2S1PT GTEx Tissue Sample Gene Expression Profiles 1.0 1.27421 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.979174 CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEG-01 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.535 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16453 Perturb_5169_KO_Ddx5_SRP068412 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.85231 POU2F2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial parabrachial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.11434 GTEX-SNOS-1726-SM-32PLN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.78432 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null AE-39-DG66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.281955 ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null subcuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11649 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QCQG-1926-SM-2S1PI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.937688 AD-16-HL96_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.523494 TAF1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.973774 CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 2313_DNM2_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.522164 mantle zone of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06497 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.827136 GSE227592_6_v_1_adar_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Leaf vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.834 GTEX-RVPU-2426-SM-2XCAR GTEx Tissue Sample Gene Expression Profiles 1.0 1.24056 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17739 STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles 1.0 1.28877 QE-79-XO29_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.889386 superficial stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99129 HES7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.0579 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01372 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25815 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.03103 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18524 GSE184902_4_v_1_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.975411 GTEX-QXCU-0626-SM-2TC69 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.84648 GTEX-TKQ1-0008-SM-4DXSO GTEx Tissue Sample Gene Expression Profiles 1.0 0.998369 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.825091 H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE44157,GSE44163_1_v_0_nr6a1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SNU-175 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.8809 Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1854 pancreas_6a HPA Tissue Sample Gene Expression Profiles -1.0 -0.824798 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01480 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.02481 GSE239688_2_v_1_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null FE-10-KQ78_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.976491 SIRT6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH684 CCLE Cell Line Gene Expression Profiles 1.0 1.42251 GB-73-QS80_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.271995 TA-34-CK62_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.99756 hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.21018 Artery disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.8 JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.04875 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42795 principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17418 skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles 1.0 1.58383 GTEX-TMMY-1026-SM-4DXTI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13026 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.865379 GNG4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60507 SIN3A_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6032_KD_LOXL2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-R55F-1526-SM-2TF4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.60301 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25106 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GF-35-IT27_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.396742 Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0916 TAF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EC-82-LV30_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.244701 olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.877714 RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940993 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles 1.0 1.77534 GTEX-QEG4-0526-SM-48TZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39058 GTEX-S4Z8-1826-SM-3K2BH GTEx Tissue Sample Gene Expression Profiles 1.0 1.10758 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC70 CCLE Cell Line Gene CNV Profiles 1.0 1.73127 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BC-62-RZ55_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.55913 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.61393 Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5K8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TUHR10TKB CCLE Cell Line Gene Expression Profiles -1.0 -1.60276 HCC366 CCLE Cell Line Gene Expression Profiles -1.0 -1.51569 Lateral reticular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2821 TD-48-XJ84_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.977512 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34919 ES-I3 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.2822 H3K9me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6831-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NALM-6 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.7998 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r7 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23492 NCIH854 CCLE Cell Line Gene CNV Profiles 1.0 2.02124 GTEX-U8T8-1226-SM-4E3IH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26049 KM-12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.41236 AC-55-XA97_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.275119 GSE84922,GSE84924_0_v_1_sall4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K79me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF ChEA Transcription Factor Targets 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.3998 GTEX-S4Q7-1326-SM-4AD74 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904954 motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.947007 H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC56 CCLE Cell Line Gene Expression Profiles 1.0 1.56903 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC1 ENCODE Transcription Factor Targets 1.0 null HS852T CCLE Cell Line Gene Expression Profiles -1.0 -2.59237 H3K27ac_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877261 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.96224 GTEX-S7SF-0008-SM-3NM8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.1902 IGR39_SKIN CCLE Cell Line Proteomics 1.0 2.97461 KICSTOR complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.766 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC12364684-DataSheet1.pdf-22-ENSG00000130522_JUND Rummagene Transcription Factor Associations 2026 1.0 null vorinostat_homo sapiens_gpl10558_gse35242 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.47193 Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72138 JB-23-ZE86_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.408662 MHHCALL3 CCLE Cell Line Gene CNV Profiles -1.0 -1.60209 Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_11_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null RD-92-QT24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.357954 ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.932661 GSE111881_0_v_1_znf768_human RummaGEO Gene Perturbation Signatures 1.0 null SCYL1_knockdown_194_GSE57646 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.37408 CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE239688_2_v_5_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07357 stomach HPA Tissue Protein Expression Profiles 1.0 0.776627 CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJHI-0626-SM-3DB8T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.900309 molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72404 embryoday6.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.906904 bone marrow HPA Tissue Gene Expression Profiles -1.0 -2.05869 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15123 POLR2A_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE179002_0_v_7_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE152055_0_v_1_mpc1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ELF1 ChEA Transcription Factor Targets 1.0 null TCF12_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MS-0626-SM-2YUN7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56106 H3K4me3_Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NUGC4 CCLE Cell Line Gene Expression Profiles 1.0 1.65252 RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.883165 POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40358 Lung adenocarcinoma_LUAD_TCGA-38-4629-01A-02R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.61987 ABL1_knockdown_137_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.0889 GTEX-SNMC-1426-SM-2XCFM GTEx Tissue Sample Gene Expression Profiles 1.0 2.11753 Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_9812_KD_CNOT3_SRP117693 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.22564 Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC103 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04596 ChIP_CTCF_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null C32 CCLE Cell Line Gene CNV Profiles -1.0 -1.83607 CTCF_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEL4-0626-SM-3GIJM GTEx Tissue Sample Gene Expression Profiles 1.0 1.04804 CTCF_GM20000_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86606 RCC4 CCLE Cell Line Gene CNV Profiles -1.0 -1.34065 CTCF_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null Oropharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.926 Perturb_6101_KD_ZNF638_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25815 heart muscle HPA Tissue Protein Expression Profiles 1.0 0.776627 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SA-31-VB03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.277241 A-431 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.950702 H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null IRF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.4529 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Arthritis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null diethylstilbestrol_mus musculus_gpl6887_gse37969 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.01199 SPI1 ChEA Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUJ4-0008-SM-4BOQI GTEx Tissue Sample Gene Expression Profiles 1.0 1.00843 Corpus allatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.727 H3K36me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0726-SM-3DB8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50953 hsa-miR-2682 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GTEX-X5EB-2626-SM-4E3HZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30171 Lobules IV-V, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03407 GTEX-T6MO-0008-SM-4DM6T GTEx Tissue Sample Gene Expression Profiles 1.0 1.05671 MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44413 DNA recombinase mediator complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.849 NALM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.61835 CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4909989-ncomms11840-s3.xlsx-Sheet1-The_overlapped_genes_regulated_by_YAP_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.887586 HMGN3 ENCODE Transcription Factor Targets 1.0 null U118MG CCLE Cell Line Gene Expression Profiles -1.0 -2.06465 GSE227592_2_v_1_adar_human RummaGEO Gene Perturbation Signatures 1.0 null AF-99-HA02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -6.64381 H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.855711 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.09543 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LEF1-29337183-MESC-MOUSE-STEM ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM5B ENCODE Transcription Factor Targets 1.0 null KAT2A ENCODE Transcription Factor Targets 1.0 null GSE171572_5_v_2_tp53_human RummaGEO Gene Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.04885 AIRE_KO_GDS2274_245_mouse_Medullary thymic epithelial cells (with low CD80 expression) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.74975 BD-66-QO48_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.216992 S0-EE-WJKI_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.609616 Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 8288_SOX2_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.623725 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H1-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3412 SKMEL3 CCLE Cell Line Gene CNV Profiles -1.0 -1.37275 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.5909 GSE111247_2_v_6_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.62024 HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03501 DD-75-HY40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.40597 E2F6 ENCODE Transcription Factor Targets 1.0 null PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.940534 MYOG_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EGFR_drugactivation_20_GDS2146 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.573 PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-12_names_TP53 Rummagene Transcription Factor Associations 2026 1.0 null endoribonuclease complex GO Cellular Component Annotations 2025 1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -2.49647 POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.931315 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPM-0526-SM-2YUMJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0204 POLR2A_GM10847_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sirolimus_mus musculus_gpl1261_gse5332 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PC-18-VX23_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.494117 AC-30-XU83_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.381637 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.52087 TMEM39A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5118 HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.922431 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null skeletal muscle HPA Tissue Gene Expression Profiles 1.0 2.24623 nb4 HPA Cell Line Gene Expression Profiles 1.0 1.62486 short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.903081 H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYBS-0626-SM-3NMAS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873026 789_BCCIP_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.554912 ARID3A ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.906339 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUW1-0826-SM-4BOP6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54219 TGDS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04026 Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE221327_8_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null ZBTB24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.4988 H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null tRNA 5'-leader removal GO Biological Process Annotations 2023 1.0 null Subesophageal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.837 PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3998 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZM-1226-SM-3DB9G GTEx Tissue Sample Gene Expression Profiles 1.0 1.0243 ZNF491 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73073 HEP3B217 CCLE Cell Line Gene Expression Profiles -1.0 -1.53564 GSE89154_1_v_0_proscillaridin_human RummaGEO Drug Perturbation Signatures -1.0 null QA-07-KC40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.432381 GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53622 intracellular membrane-bounded organelle GO Cellular Component Annotations 2015 1.0 null intermediate part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15776 H3K36me3_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100359_PCx_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.14365 GTEX-R45C-0008-SM-48FF2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.943907 RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17692 SET2 CCLE Cell Line Gene CNV Profiles -1.0 -1.3922 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955057 amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.42648 RNF126 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10368 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 15120961-Figure6 GeneSigDB Published Gene Signatures 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE203158_0_v_13_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE124375_13_v_12_chd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null skeletalmuscle_c HPA Tissue Sample Gene Expression Profiles 1.0 1.62469 r6 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06061 outer SZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.920104 CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypertension DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.8 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.26457 GTEX-OXRK-1726-SM-3NB16 GTEx Tissue Sample Gene Expression Profiles 1.0 0.947912 intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Ribonuclease P complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.91 GTEX-RWS6-2326-SM-2XCB4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.81863 TFAP2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF12_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.991954 WM983B CCLE Cell Line Gene CNV Profiles -1.0 -3.19633 Breast_Myoepithelial_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.878869 TAF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HAX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.06686 Necrosis CTD Gene-Disease Associations 1.0 1.23806 valproic acid_homo sapiens_gpl6883_gse26940 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null mantle zone of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05873 PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D1_1591_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.10794 ChIP_MYC_19079543 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-OOBK-1626-SM-2HMKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.38034 mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65229 GSE165122_0_v_1_metformin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1076 CCLE Cell Line Gene Expression Profiles 1.0 1.88875 496100419_TCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.1252 GTEX-QEG4-0626-SM-2S1OY GTEx Tissue Sample Gene Expression Profiles 1.0 0.972251 GTEX-R55D-0626-SM-3GAD5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.77494 superficial stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.51397 GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles 1.0 0.883369 GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.942784 TAF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21833 RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.986108 RA-42-CM42_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.233887 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DC-47-KV62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.213351 Nuclear exosome targeting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.607 GSE48812_2_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null H3K36me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T8EM-1326-SM-3DB7G GTEx Tissue Sample Gene Expression Profiles 1.0 0.981551 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3458-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IFNLR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38576 POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YV-1626-SM-2YUNJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.976308 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.78847 NFATC1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-4766-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 NFIC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16552 H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.82202 MZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.840745 CTCF_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.99191 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.904569 CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7PM-0426-SM-3NM91 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.05831 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KA-75-LP02_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.235154 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.11736 GTEX-QEG5-0926-SM-2TC64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00873 AB-33-EM56_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.54437 STAT5A ENCODE Transcription Factor Targets 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77502 RUNX3 ENCODE Transcription Factor Targets 1.0 null H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.6092 DNA/RNA-binding protein Alba-like InterPro Predicted Protein Domain Annotations 1.0 null CE-96-GH46_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.00974 BC-94-GN01_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.241742 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YA-78-MS95_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.428824 CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRP-0126-SM-3NB32 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.990557 PCDHB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61382 H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YW-3026-SM-3MJHI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845678 Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYOG ENCODE Transcription Factor Targets 1.0 null GTEX-QDVN-0008-SM-48U2D GTEx Tissue Sample Gene Expression Profiles 1.0 1.09605 GTEX-OIZH-3026-SM-3NB1G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24493 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTDK-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.59 H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.53521 SIN3A ENCODE Transcription Factor Targets 1.0 null MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.992877 GSE160083,GSE160084_1_v_0_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null CB-44-RT90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.740671 CDK8_knockdown_130_GSE30816 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.01058 CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ3S-0626-SM-4BOOB GTEx Tissue Sample Gene Expression Profiles 1.0 1.36053 GSE239541_11_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE255680_2_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null EFO27 CCLE Cell Line Gene CNV Profiles -1.0 -1.39805 H3K36me3_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anauxetic dysplasia 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.038 outer SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835926 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE57871_1_v_9_vorinostat_human RummaGEO Drug Perturbation Signatures -1.0 null E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CD-05-PU90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -5.1601 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-605 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01197 Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2674 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05052 blastocysts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.951971 SCLC21H CCLE Cell Line Gene Expression Profiles -1.0 -2.2318 GTEX-PWCY-2226-SM-2S1OP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65724 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE200673,GSE200691_2_v_4_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GA-47-MH68_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.742959 TAF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.53843 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.28173 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5998_KD_CBX1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 RAD21_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null ELK1 ChEA Transcription Factor Targets 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE193258,GSE193259_5_v_14_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58813 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.42422 CTCF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null stratum pyramidale of caudal CA3 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08496 CTCF_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEG4-0426-SM-33HC3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.887672 mantle zone of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.31869 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.983865 SMC3 ENCODE Transcription Factor Targets 1.0 null GSE142210_3_v_8_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.62419 GTEX-X4XY-0326-SM-46MVZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17945 PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18 Rummagene Transcription Factor Associations 2026 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 0.776627 JHUEM3 CCLE Cell Line Gene Expression Profiles -1.0 -1.83188 GSE179002_4_v_7_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4016 superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07802 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.957532 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null rectum HPA Tissue Protein Expression Profiles 1.0 0.776627 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972616 GTEX-PLZ5-1726-SM-2I5F6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.75109 6071_PARK7_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures -1.0 -0.512922 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.45534 GTEX-SJXC-0426-SM-2XCFH GTEx Tissue Sample Gene Expression Profiles -1.0 -2.06174 Retrocerebral complex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.672 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.832694 ANP32D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11712 RAD21_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WE-48-PP43_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.52226 MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2BK12ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null WC-09-GD62_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.55186 Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09438 DC-70-EK34_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.2849 CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UACC-893 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.95222 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.53998 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null RNA binding GO Molecular Function Annotations 2023 1.0 null KC-48-OO62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.17251 H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30218 SCN1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09537 inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.975497 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00399 GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3313 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P4PP-1026-SM-3NM9O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0002 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42962 CTCF_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BC-10-SB73_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.38339 16872506-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null GSE112763,GSE112767_4_v_5_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.983409 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.85398 r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15071 RELA JASPAR Predicted Transcription Factor Targets 1.0 null AP-2rep MotifMap Predicted Transcription Factor Targets 1.0 null ATF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DONSON CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28175 CD24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55745 YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DA-81-VY50_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.429613 GTEX-PLZ6-1626-SM-3NB23 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20752 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 3.24385 7489_RPP25L_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures -1.0 -0.52444 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21153 YA-78-MS95_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.277698 Perturb_6085_KD_WDR46_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PD-05-HV36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.700477 TRIM28_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-0426-SM-2TF4U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06473 Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AC-84-QG99_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.43876 GTEX-XQ3S-0126-SM-4BOO9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20714 PMC6109294-13045_2018_650_MOESM1_ESM.xlsx-ST12_KEGG_JURKAT-Unnamed_11_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47638 FBXO7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56893 MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AC-56-ZV05_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.271645 deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60225 AC-36-TL21_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.371859 496100652_PCx_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.17436 GB-46-CK08_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.652313 cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Prdm15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.3509 pc3 HPA Cell Line Gene Expression Profiles 1.0 1.22691 HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.55919 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HELA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17655 GTEX-WFG7-0626-SM-4LMK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.869574 TRIM39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39821 TAL1 ENCODE Transcription Factor Targets 1.0 null GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02667 RAJI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.61054 Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AB-18-YN11_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.95171 SETDB1-19884255-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FF-86-NH56_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.366244 U-251MG cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.816 IRF1 ENCODE Transcription Factor Targets 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.897258 H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 174.649 CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE239541_5_v_7_bmal1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Posterolateral visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02327 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03501 SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.65129 H3K79me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE165548_2_v_13_gemcitabine_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_GM12801_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE244730_0_v_1_erlotinib_human RummaGEO Drug Perturbation Signatures 1.0 null FF-28-ES17_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.84796 GTEX-OXRL-1826-SM-2YUMV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.895856 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81195 GTEX-PVOW-1026-SM-2XCF9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03365 WHSC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43343 RAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04162 VDR ChEA Transcription Factor Targets 1.0 null MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06326 LU-65 COSMIC Cell Line Gene CNV Profiles 1.0 2.59653 heart_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.914839 Dense fibrillar component COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.64 POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1 ENCODE Transcription Factor Targets 1.0 null GSE206870,GSE206872_1_v_5_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92278 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4114-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUYS-0326-SM-47JX2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.93388 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of r7Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23416 Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3545 BB-44-SX65_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.589752 GA-28-SS67_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.521685 GSE142210_2_v_8_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.31559 claustrum, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.985736 RAD21_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AI-0008-SM-48U2H GTEx Tissue Sample Gene Expression Profiles 1.0 1.64597 PMC7782698-41467_2020_20367_MOESM9_ESM.xlsx-Student_s_t-test_BP1_ILK_GFP-Gene_names_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.903764 Lung adenocarcinoma_LUAD_TCGA-35-3615-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Main olfactory bulb, inner plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0223 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0011-R9A-SM-2HMJ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.835956 ISTMES1 CCLE Cell Line Gene Expression Profiles -1.0 -1.52345 3086_FIP1L1_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.50726 H3K36me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13175 H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5365_KO_Mettl14_SRP297324 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.77877 SP1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles 1.0 1.2478 RAD21_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.28867 mantle zone of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68868 Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23744 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6003_KD_CCDC86_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-XQ8I-1726-SM-4BOQB GTEx Tissue Sample Gene Expression Profiles 1.0 0.849829 GTEX-QV31-1626-SM-2S1QC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00605 TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CF-65-GU65_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.30653 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MN-0426-SM-32PMF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27546 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18626 RA-27-ST16_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.854927 GTEX-XUJ4-2026-SM-4BOOW GTEx Tissue Sample Gene Expression Profiles 1.0 1.20105 C170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.907775 CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25106 r7 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28945 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.968247 H3K36me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BT-20 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.91136 ED-02-CL76_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.724287 TAL1_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.93361 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7068-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04764 PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WOFM-1326-SM-3MJFR GTEx Tissue Sample Gene Expression Profiles 1.0 1.44047 OCI-AML2 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.622 GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles 1.0 1.45402 GSE146982_7_v_6_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.13337 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43525 CD4_Memory_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.13025 GTEX-SN8G-0008-SM-4DM4X GTEx Tissue Sample Gene Expression Profiles 1.0 1.13078 GSE239578_0_v_4_cxadr_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F2_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_7198_KD_ICE1_SRP164752 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 alpha,alpha-trehalose-phosphate synthase complex (UDP-forming) COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.879 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33546 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FU97 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.4963 Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57032 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-O5YV-2026-SM-2D7VS GTEx Tissue Sample Gene Expression Profiles 1.0 1.21078 GSE213588_8_v_6_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KC-32-GO33_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.579534 Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.95286 Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary auditory cortex (core)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.852972 H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.1373 DC-23-UM36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.298211 H3K79me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-1226-SM-3NMA5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05884 Dendritic lamellar body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.931 CHP126 CCLE Cell Line Gene Expression Profiles -1.0 -3.56329 intermediate stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09032 A-Vietnam-1203-2004(H5N1)_24Hour_21865398_GSE28166 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.41464 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-0526-SM-2S1PW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77482 inner CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.911356 PC-87-OG75_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.252418 GSE149854_1_v_0_batf_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QCQG-0008-SM-48U2G GTEx Tissue Sample Gene Expression Profiles 1.0 1.54023 UBC Pathway Commons Protein-Protein Interactions 1.0 null PA-75-VL17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.79298 Endoribonuclease complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.394 SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.16032 GTEX-VUSG-0526-SM-4KL22 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902177 TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null BD-49-MD69_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -8.18344 Edinger-Westphal nucleus (accessory oculomotor nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.6955 AA-62-HP31_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.755385 Root primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.779 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.859488 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KE-24-RZ94_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.229209 GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14334 E2F4 ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAOV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.07343 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81947 GSE225218_8_v_3_abcb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MYC ChEA Transcription Factor Targets 1.0 null CTCF_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null OF-05-CB18_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.6029 MT-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10488 EE-03-SG02_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.719768 FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14002_KD_Dek_SRP376103 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.79785 POLR2A_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null xth2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.119 inner SZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.856218 Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.86022 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QT-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.764158 GTEX-OXRL-0008-SM-3NB29 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33552 CF-24-KQ98_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.202701 hsa-miR-423-3p MiRTarBase microRNA Targets 1.0 null NFKB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9313 cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 SARS-dORF6_48Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.71381 GTEX-RU72-0226-SM-46MUD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00069 H3K36me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r1 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5289 GSE169356_0_v_1_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44337 H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCIH2110 CCLE Cell Line Gene Expression Profiles -1.0 -1.45773 POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GAK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31893 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sno(s)RNA-containing ribonucleoprotein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.752 SF-67-CJ22_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.381995 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null Granulosa cell_Fetal gonad_Human CellMarker Gene-Cell Type Associations 1.0 null GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles 1.0 1.10196 LA-42-ER00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.05071 BD-96-HO33_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.19908 ficolin-1-rich granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.84 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F6_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20645 Perturb_12002_KD_E2F1_SRP109107 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.50683 EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medial geniculate complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25114 H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-0011-R9A-SM-2TF67 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01822 MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874665 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles 1.0 2.30822 GSE184884_4_v_1_gps2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Autoimmune disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 STAT5A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.52397 GTEX-VUSG-0926-SM-3GIK6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06081 H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6034_KD_MATR3_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.1966 PMC11073998-41375_2024_2235_MOESM9_ESM.xlsx-THP1_phosphoproteome-Unnamed_2_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IF-87-AU84_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.207956 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67R-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBM22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36586 H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null AD-16-HL96_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.607803 ventrolateral periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44919 GSE162892_4_v_5_isox_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08945 deep layers of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37503 OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.08286 SAP30 ENCODE Transcription Factor Targets 1.0 null GTEX-TKQ1-0226-SM-33HB5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847101 skeletalmuscle_e HPA Tissue Sample Gene Expression Profiles 1.0 2.29608 IB-33-TE51_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.70534 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AF-99-HA02_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.786931 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.864868 Nuclear lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.545 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948727 GSE86507,GSE86509_0_v_8_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27552 cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70618 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.996961 GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.45017 YY1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4949 GTEX-QVJO-0526-SM-447CE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861188 skin TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48894 PMC8986528-41586_2022_4598_MOESM6_ESM.xlsx-Fig_4h-LAS1L_KD_upreg_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X638-0326-SM-47JY1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.59352 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868158 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -2.24103 GTEX-WFON-2326-SM-3LK7M GTEx Tissue Sample Gene Expression Profiles 1.0 1.77799 USF1 ENCODE Transcription Factor Targets 1.0 null CTBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.00858 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43602 GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles 1.0 1.40343 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33556 IRF1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-CA-04-2009(H1N1)_12Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.47771 GTEX-OXRO-1926-SM-2S1O3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0087 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.95588 NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.76089 Anterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00903 GTEX-S33H-1826-SM-4AD65 GTEx Tissue Sample Gene Expression Profiles 1.0 0.864176 PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-D-Enh_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.973713 H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MC-40-IP75_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.291264 GSE152050,GSE152052_1_v_0_arid1a_mouse RummaGEO Gene Perturbation Signatures 1.0 null CEBPB_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r5BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15635 Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06042 ZNF416 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39816 GTEX-XGQ4-2426-SM-4AT55 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8825 S0-EE-YC7H_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.881058 GTEX-S7PM-0526-SM-3NM92 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962563 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04812 Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.998327 H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fetal_Brain_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.20723 POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE184902_4_v_1_adipor1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WL46-0526-SM-3LK7W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39784 GB-46-CK08_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.98954 GTEX-WHPG-2326-SM-3NMBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09251 9226_TRAF2_P1 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.515337 bonemarrow_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.59404 GTEX-XBEW-0008-SM-4AT3Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.950046 GSE193282_2_v_0_cd44_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61958 RBBP5 ENCODE Transcription Factor Targets 1.0 null H3K36me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM1A ENCODE Transcription Factor Targets 1.0 null intermedioposterior nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01439 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.841022 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T5JW-0126-SM-4DM6K GTEx Tissue Sample Gene Expression Profiles 1.0 0.864368 KB-46-EJ60_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -5.02064 HDAC2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49279 GTEX-S7SE-0526-SM-2XCD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40993 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DE-98-FC24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.529772 GTEX-PLZ6-1526-SM-2S1OC GTEx Tissue Sample Gene Expression Profiles 1.0 1.53932 NUGC4 CCLE Cell Line Gene CNV Profiles 1.0 1.38025 hsa-miR-4747-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 DLGAP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18556 posteroventral (inferior) parietal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01024 CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RSAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.24051 KA-71-CQ35_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.366395 GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.8739 Perturb_13511_OE_Nfkbiz_SRP234708 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.23076 H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE186633_2_v_0_chd1_human RummaGEO Gene Perturbation Signatures -1.0 null MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MT-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACTR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42476 BD-69-GX17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.75261 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17695 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null WC-82-YS26_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.546654 tRNA 5'-leader removal GO Biological Process Annotations 2025 1.0 null H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autoimmune disease of musculoskeletal system DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07142 WC-09-GD62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.343224 GTEX-V1D1-2426-SM-3GAER GTEx Tissue Sample Gene Expression Profiles 1.0 0.842083 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.920641 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles 1.0 2.26378 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01433 GTEX-WHSE-1126-SM-3NMBU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.70097 Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null small intestine HPA Tissue Protein Expression Profiles 1.0 0.776627 superior periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22443 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22105 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FA-63-WI26_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.885547 GTEX-SNMC-0926-SM-4DM5U GTEx Tissue Sample Gene Expression Profiles 1.0 0.904853 BE-79-QU25_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.666175 SJSA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.69106 GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.30452 GTEX-UJHI-1926-SM-3DB8Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.988447 HSC-39 COSMIC Cell Line Gene CNV Profiles 1.0 2.59653 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.831843 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03159 H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7254 gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.134578 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.4597 FF-06-MO73_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.204499 Paragigantocellular reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36614 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.947981 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.963524 H3K36me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GE-77-FY84_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.349154 HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09576 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.19566 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE244072_10_v_8_tfeb_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0726-SM-2TF4M GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20291 CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-1126-SM-2XCAZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.9594 8651_TAF10_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.586351 POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WWYW-0526-SM-3NB2W GTEx Tissue Sample Gene Expression Profiles 1.0 1.81053 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.406 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Ribonuclease MRP complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.71 YY1_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126463_4_v_2_arid2_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0008-SM-48U2K GTEx Tissue Sample Gene Expression Profiles 1.0 1.77782 SN12C Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.31149 AD-51-SS86_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.32613 EP300 ENCODE Transcription Factor Targets 1.0 null PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1 Rummagene Transcription Factor Associations 2026 1.0 null Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YD-49-HM53_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -9.02196 PBX3 ENCODE Transcription Factor Targets 1.0 null SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-0826-SM-4BOOE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.882457 GSE256181_1_v_3_etv2_human RummaGEO Gene Perturbation Signatures -1.0 null ELF5 JASPAR Predicted Transcription Factor Targets 1.0 null BB-62-SZ35_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.646812 H3K4me1_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Creb3l2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.7695 H3K27ac_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69267 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bone inflammation disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 GTEX-T5JC-0226-SM-32PMA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42678 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles 1.0 1.7775 H3K79me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MEWO CCLE Cell Line Gene CNV Profiles -1.0 -2.136 GSE231745_1_v_0_venetoclax_human RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PANC0213 CCLE Cell Line Gene CNV Profiles 1.0 1.38218 GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11532 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42795 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92278 EBF1 ENCODE Transcription Factor Targets 1.0 null RAD21_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MTA3 ENCODE Transcription Factor Targets 1.0 null GTEX-QESD-0008-SM-447B2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.901401 TAF1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17491 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XE-01A-12R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE178907_5_v_3_fkrp_human RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRF_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null AE-56-SL06_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.348972 GTEX-WZTO-1326-SM-3NM8X GTEx Tissue Sample Gene Expression Profiles 1.0 1.14741 PSMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40359 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239688_2_v_3_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null 496100495_FWM_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.29848 POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SUZ12 ENCODE Transcription Factor Targets 1.0 null JD-44-KF86_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.31615 GTEX-T6MN-0926-SM-32PLX GTEx Tissue Sample Gene Expression Profiles 1.0 0.981967 SARS-dORF6_0Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -3.13578 POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211286_4_v_6_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null TAF7_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6007_KD_CUX1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NCIH2106 CCLE Cell Line Gene Expression Profiles -1.0 -2.91727 GTEX-X62O-0008-SM-46MU5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08844 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.896855 MXI1 ENCODE Transcription Factor Targets 1.0 null PBX3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPL-0426-SM-3TW8X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19556 HK2 CCLE Cell Line Gene Expression Profiles -1.0 -1.86898 CTCF_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-1526-SM-2XCFN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58165 GB-57-XV52_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.547992 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-0008-SM-447AV GTEx Tissue Sample Gene Expression Profiles 1.0 0.921118 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SW1116 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.60584 Renal clear cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.695 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.827027 superficial stratum of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.31869 H3K36me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1666 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.824272 CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EKLF-21900194-ERYTHROCYTE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null ESR1-26153859-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06326 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.879806 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09794 MYC-19030024-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Urinary bladder TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.127 CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EJM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07142 RPMI-7951 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.11938 PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE180200,GSE180201_2_v_0_qpctl_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.839 ROCK_INHIBITION_GDS3944_461_mouse_Forebrain astrocytes - 2 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TIMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86372 SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.70145 Synpolydactyly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68937 GSE206516,GSE206518_0_v_7_ptdss2_human RummaGEO Gene Perturbation Signatures -1.0 null 9172_TONSL_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.534139 CW-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null RAD21_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FF-28-ES17_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.55911 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.873034 Ribosome biogenesis in eukaryotes KEGG Pathways 2026 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22288 POLRMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12485 PMC8755726-42003_2021_2958_MOESM6_ESM.xlsx-489_corr_genes_TWIST1_signature-Gene_name_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null CF-50-QK79_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.328985 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FD-91-OK66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -6.17923 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.16949 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877261 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.36637 GA-88-CF36_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.56157 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6082_KD_TRA2B_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SUPHD1 CCLE Cell Line Gene Expression Profiles 1.0 1.99153 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AD-18-XC14_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.49899 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13073 lateral part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89055 GSE236454,GSE236456_0_v_1_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures 1.0 null AD-66-NV75_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.203613 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1485 CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE133683_1_v_5_doxorubicin_mouse RummaGEO Drug Perturbation Signatures 1.0 null TAF7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3 ENCODE Transcription Factor Targets 1.0 null EA-18-FP00_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.228788 GSE186647,GSE217287_1_v_3_hnrnpc_human RummaGEO Gene Perturbation Signatures 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDK2_knockdown_132_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.78901 CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JD-81-YX02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.1301 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral reticular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29769 SRF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V1D1-1926-SM-4JBGX GTEx Tissue Sample Gene Expression Profiles 1.0 1.1819 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.73743 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-0008-SM-4DM6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.24883 E2F1 ChEA Transcription Factor Targets 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_Panc1_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NELFE ENCODE Transcription Factor Targets 1.0 null Perturb_6052_KD_PRDM15_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.96856 CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.863815 LC-12-VN85_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.267255 H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZH-1926-SM-4DXTR GTEx Tissue Sample Gene Expression Profiles 1.0 1.28511 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.883428 BA-84-WN26_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.22348 PF-59-CY33_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.411932 intermediate stratum of p3B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15209 H3K79me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46549 496100666_HIP_probable Alzheimer's disease_TBI_83_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.1637 GTEX-U3ZH-0626-SM-4DXT3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43334 CE-69-HJ13_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.289323 CTCFL_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AH-2026-SM-2S1PX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25735 Plantlet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.014 PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1c-List_of_1682_genes_differentially_regulated_by_GLI1_FDR_0_1_GLI1 Rummagene Transcription Factor Associations 2026 1.0 null BC-54-ON71_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.287517 primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.831998 UACC62_SKIN CCLE Cell Line Proteomics 1.0 13.3555 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.14379 outer SZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.907151 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.37534 PBX1 ChEA Transcription Factor Targets 1.0 null central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00429 TCF7-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE132408_1_v_3_tet2_human RummaGEO Gene Perturbation Signatures -1.0 null CB-62-TB77_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.237211 Spermatheca TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.57 POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPP2R5C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1114 r6 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44218 skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07055 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PB-18-HD85_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.234833 17638893-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.880871 GTEX-TML8-1826-SM-32QOR GTEx Tissue Sample Gene Expression Profiles 1.0 1.59593 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.08373 r10 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69265 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.49702 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62361 H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GRPEL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6885 GSE222758_0_v_3_clofazimine_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE211286_7_v_5_tcf12_mouse RummaGEO Gene Perturbation Signatures -1.0 null TBL1XR1 ENCODE Transcription Factor Targets 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.29657 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHPG-2226-SM-3NMBO GTEx Tissue Sample Gene Expression Profiles 1.0 0.954344 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19236 MELJUSO_SKIN CCLE Cell Line Proteomics 1.0 2.13439 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1526 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.874806 thyroid gland HPA Tissue Protein Expression Profiles 1.0 0.776627 PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1 Rummagene Transcription Factor Associations 2026 1.0 null ME-31-RM40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.66101 LA-42-ER00_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.261098 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XOTO-0526-SM-4B662 GTEx Tissue Sample Gene Expression Profiles 1.0 1.55022 ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.9936 POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.16058 hsa-miR-3690 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 medial part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21241 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07142 Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S7SF-2226-SM-3K2BG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52458 DA-66-OE69_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.03017 TCF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE164757,GSE164759_4_v_2_trametinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null colo704 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.446 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null transverse gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.915166 RAD21_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GC-04-UF36_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.251679 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.996795 YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-LY-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.825091 GSE140651,GSE140653_5_v_7_med1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S3XE-0326-SM-4AD6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77184 subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86139 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.84042 GTEX-VJYA-1126-SM-3GIJU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.917203 Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-1026-SM-32QP1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32153 Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_DEPLETION_GDS3294_97_mouse_germinal vesicle (GV) oocytes GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null NFIC ENCODE Transcription Factor Targets 1.0 null tRNA-splicing ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.155 CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.807 POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AA-56-JY17_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.369624 H3K36me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPI1-23547873-NB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FOXP2 ENCODE Transcription Factor Targets 1.0 null POLR2A_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE206270_2_v_3_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WYJK-0005-SM-3NMA1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45517 Lung squamous cell carcinoma_LUSC_TCGA-37-3792-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPN-0011-R2A-SM-2I5FB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.999951 Perturb_6089_KD_YBX3_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q2AG-1026-SM-33HBW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.1498 H3K4me1_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_14-Supplementary_Table_14_ETV6-activated_genes_defined_by_dTAG_at_72_hours_ETV6 Rummagene Transcription Factor Associations 2026 1.0 null Perturb_6096_KD_ZNF326_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null AB-74-VK99_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.309362 GTEX-PSDG-0926-SM-2I5FP GTEx Tissue Sample Gene Expression Profiles 1.0 0.971785 HD-51-KD29_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -7.20556 POLR2A_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 3436_RACK1_P1P2 Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures 1.0 1.15339 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UJMC-0626-SM-4IHJQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.85585 GSE199899_4_v_0_diethylnitrosamine_mouse RummaGEO Drug Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26181 GSE77178_2_v_3_ccnd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21-21589869-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69709 rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.527511 GSE184356_3_v_0_tfam_human RummaGEO Gene Perturbation Signatures 1.0 null GSE132369,GSE132371_5_v_0_cccp_human RummaGEO Drug Perturbation Signatures 1.0 null H3K36me3_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852341 BA-56-QV45_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.15194 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879914 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BE-79-QU25_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.941123 GTEX-XQ8I-0126-SM-4BOPL GTEx Tissue Sample Gene Expression Profiles 1.0 1.00254 VZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.889779 CTCF_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63772 FC-85-OX77_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.65362 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63615 GSE186660_2_v_1_nicotine_mouse RummaGEO Drug Perturbation Signatures -1.0 null Intraciliary transport particle B COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.108 LU65 CCLE Cell Line Gene Expression Profiles 1.0 1.93248 H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.842723 H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Dehydration_Hypothalamus_GSE3110 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.51728 GTEX-RWSA-0926-SM-47JXW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25042 GTEX-P4PQ-1626-SM-2HMKK GTEx Tissue Sample Gene Expression Profiles 1.0 4.21211 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-5141-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DD-36-YH76_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.9791 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.9576 HA-22-CY42_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.378102 LD-69-ZV56_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.373086 POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB468 CCLE Cell Line Gene CNV Profiles 1.0 1.65773 AC-47-YZ27_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.92179 GTEX-U8T8-0008-SM-4DXSP GTEx Tissue Sample Gene Expression Profiles 1.0 0.853938 r9 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.90781 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.72817 A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.38201 H3K9ac_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE142210_9_v_5_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.24415 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NCIH1437_LUNG CCLE Cell Line Proteomics 1.0 2.18625 POLR2A_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral part of the lateral habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07896 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NFK9-0326-SM-3MJGV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856766 GTEX-N7MS-0926-SM-2HMIZ GTEx Tissue Sample Gene Expression Profiles -1.0 -3.22345 7505_RPS16_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.683352 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EIF3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38959 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09576 H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE87144_3_v_1_rorc_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.23545 MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDK4_knockdown_133_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.76183 H4K5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EC-62-OE64_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.485557 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SUCS-1626-SM-32PLS GTEx Tissue Sample Gene Expression Profiles 1.0 1.0508 H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 2551_EIF3G_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.536382 GSE155031_5_v_0_dextran_human RummaGEO Drug Perturbation Signatures 1.0 null GC-04-UF36_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.90716 POU5F1-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null NB4 CCLE Cell Line Gene CNV Profiles 1.0 1.62309 PD-70-VS77_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.623752 PMC12364684-DataSheet1.pdf-22-JUND_JUND Rummagene Transcription Factor Associations 2026 1.0 null YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.923313 H3K18ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null DB-54-GQ68_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.24635 HD-29-LW24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.92025 HCC630 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97653 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.828694 GTEX-W5WG-0008-SM-4KL25 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09529 ZIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10301 CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UF-27-HS98_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.76411 Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CD-01A-21R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Medullary reticular nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22594 CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XOTO-0011-R9A-SM-4GICI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21483 GTEX-U8XE-1226-SM-4E3HN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37251 ZC3H11A ENCODE Transcription Factor Targets 1.0 null AR ChEA Transcription Factor Targets 1.0 null Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56819 GSE138841_0_v_1_trim6_human RummaGEO Gene Perturbation Signatures -1.0 null GSE73628_8_v_2_igf1_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_6024_KD_HP1BP3_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39069 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8496 Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55644 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles 1.0 1.65987 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1248 CHMP4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56646 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E16_vs_D3_1784_AR-DEGS-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DC-51-WE27_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.439441 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14342 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null DOR 13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.919171 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null WM115 CCLE Cell Line Gene CNV Profiles 1.0 1.70232 MAX_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.67033 NCI-H211 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.51741 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62304 H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K79me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-O5YT-1826-SM-32PK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.97212 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.867306 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CYP2A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14475 thyroid BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.02136 Lung squamous cell carcinoma_LUSC_TCGA-66-2765-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03682 NUDHL1 CCLE Cell Line Gene Expression Profiles 1.0 2.1815 TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.932693 POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUPT11 CCLE Cell Line Gene CNV Profiles -1.0 -1.33404 GSE183335,GSE183351_1_v_2_lin28b_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4650-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-449c TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 CE-15-YU05_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.404492 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CEBPB_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.13671 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Choanomastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.92 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.852471 Kidney - Cortex GTEx Tissue Gene Expression Profiles 2023 1.0 0.9833 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.85677 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null VZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.862474 JHH2 CCLE Cell Line Gene Expression Profiles -1.0 -1.62767 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 intracellular organelle GO Cellular Component Annotations 2015 1.0 null SRF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE179002_2_v_7_caprin1_mouse RummaGEO Gene Perturbation Signatures -1.0 null LD-69-ZV56_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.753157 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0126-SM-3GIK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22894 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE160083,GSE160084_1_v_3_tamoxifen_mouse RummaGEO Drug Perturbation Signatures 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E20-D3_1775_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26696 Perturb_6057_KD_RBM12B_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03501 AD-18-XC14_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.35392 496100457_TCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.4213 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AKT1_knockdown_135_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.48042 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8T8-1426-SM-3DB9H GTEx Tissue Sample Gene Expression Profiles 1.0 1.18779 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TFAP2C ENCODE Transcription Factor Targets 1.0 null SRF JASPAR Predicted Transcription Factor Targets 1.0 null RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9233 ChIP_SETDB1_19884255 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-PWOO-0008-SM-48TDU GTEx Tissue Sample Gene Expression Profiles 1.0 0.835339 Main olfactory bulb, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08741 POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 2977_FASTKD2_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.541504 TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null 3572_GTF2F2_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.511233 CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE203158_5_v_15_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DA-85-SU90_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.721292 ECGI10 CCLE Cell Line Gene Expression Profiles 1.0 1.85299 Cancer of Colon_Intestine - Large Intestine - Colon (MMHCC)_GSE4107 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.31023 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.867803 GTEX-XGQ4-0008-SM-4AT3Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.531 GSE120612_6_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null skeletalmuscle_d HPA Tissue Sample Gene Expression Profiles 1.0 1.65272 PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3 Rummagene Transcription Factor Associations 2026 1.0 null ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UF-27-HS98_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.97916 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO3-22982991-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE198826,GSE198911_1_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures -1.0 null CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null oxandrolone_homo sapiens_gpl97_gds1334 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.07474 AC-05-MR83_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.01019 H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mantle zone of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36705 YA-92-YO01_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.638432 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null TAF1_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EEF1G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 9.33216 RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78M-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null LP1 CCLE Cell Line Gene Expression Profiles 1.0 1.49689 H3K36me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-1826-SM-2TF5B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889615 lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46535 GTEX-OHPK-1626-SM-2YUN3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.5531 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18836 primary motor-sensory cortex (samples)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.40144 RORB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.8391 Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U412-0326-SM-3DB9L GTEx Tissue Sample Gene Expression Profiles 1.0 1.57464 PML_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCNT2 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRP-0226-SM-3NB14 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06228 VZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3655 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 15120961-Figure4 GeneSigDB Published Gene Signatures 1.0 null hsa-miR-938 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 TMEM68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07144 WDR86 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87302 GSE220058,GSE220059_0_v_1_prrc2b_human RummaGEO Gene Perturbation Signatures 1.0 null VZ in caudal cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.985819 Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.76231 GTEX-S4UY-0008-SM-3NM8H GTEx Tissue Sample Gene Expression Profiles 1.0 1.21339 mantle zone of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80757 DC-78-CM38_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.239133 GTEX-R55E-1026-SM-2TC5S GTEx Tissue Sample Gene Expression Profiles 1.0 0.969894 H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.59029 CC-03-PW00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.625626 SET2 CCLE Cell Line Gene Expression Profiles -1.0 -1.94358 NR2F2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.19164 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC ChEA Transcription Factor Targets 2022 1.0 null WHSC1 ENCODE Transcription Factor Targets 1.0 null XF-42-ES96_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.25043 CHD1 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRK-1826-SM-2HMJE GTEx Tissue Sample Gene Expression Profiles 1.0 2.29601 RAD21_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955057 GSE180200,GSE180201_15_v_1_qpctl_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4XY-0526-SM-46MW1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21749 Vascular disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.8 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cells - EBV-transformed lymphocytes GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.41181 AC-36-TL21_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.219413 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-27a-3p MiRTarBase microRNA Targets 1.0 null GSE135514_2_v_9_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null W chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.726 EA-18-FP00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.833046 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Posterior midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.673 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFJO-0008-SM-4LVN7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.966909 hsa-miR-3908 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 DD-42-PC65_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.39476 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.856551 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.825753 GSE100528_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null 6652_PPP1R10_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.846623 Posterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17335 CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14025 GTEX-WWYW-0426-SM-3NB31 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28025 GTEX-RWS6-0426-SM-47JXH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23684 Bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15397 GSE147893,GSE147897_2_v_1_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.877261 CTCF_GM12869_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RD-90-OY66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.318061 DB-54-GQ68_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.271656 Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IE-38-FB31_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.201932 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12827 FF-86-NH56_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.890693 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCFL_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE237426_0_v_1_eif4a1_mouse RummaGEO Gene Perturbation Signatures -1.0 null r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15635 ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-0326-SM-33HBO GTEx Tissue Sample Gene Expression Profiles 1.0 1.1098 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_astrocyte of the cerebellum_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF354A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06205 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8 Rummagene Transcription Factor Associations 2026 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EBNA2-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-S95S-1626-SM-2XCDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916194 CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null AB-18-YN11_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.926902 H3K79me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.75484 WE-43-PZ45_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.13364 Lung squamous cell carcinoma_LUSC_TCGA-77-8009-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.85767 Endodeoxyribonuclease complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.737 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PSDG-0526-SM-2S1OH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09654 Musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 BE-31-XV38_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.221038 Primary somatosensory area, unassigned, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39381 CA-75-HA22_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.26917 MAFF ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A262-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51391 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45125 H3K36me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIRT6 ENCODE Transcription Factor Targets 1.0 null Perturb_12250_KD_TRA2A/TRA2B_SRP044265 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 18.2441 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.980755 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01163 CTCF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6002_KD_CCDC59_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-T5JW-1126-SM-4DM5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.867129 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.353 GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.33247 CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20658 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.60127 H3K36me3_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S3XE-1826-SM-3K2B4 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.45908 IC-28-HS37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.17106 intermediate stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52669 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.09206 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.953786 H3K36me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCIAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06112 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.991981 Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles 1.0 2.77653 VDR-23849224-CD4+-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE205070_1_v_5_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WYJK-1026-SM-3NM8W GTEx Tissue Sample Gene Expression Profiles 1.0 0.999866 8505C_THYROID CCLE Cell Line Proteomics 1.0 2.13439 BF-22-EP86_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.32655 heart_5b HPA Tissue Sample Gene Expression Profiles 1.0 0.918623 CA-75-HA22_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.09459 dorsal periolivary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19558 trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.56986 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null YY1_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE120612_4_v_0_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null GSE232558_0_v_2_fbxl12_human RummaGEO Gene Perturbation Signatures -1.0 null GSE186483_1_v_4_lrrk2_mouse RummaGEO Gene Perturbation Signatures -1.0 null T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955057 GSE139455_4_v_6_stat3_human RummaGEO Gene Perturbation Signatures 1.0 null AC-30-XU83_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.33725 LA-42-ER00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.56521 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null CD8_Naive_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.11091 BB-11-JI42_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.29555 H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null LNCAP Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.25009 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Plagl1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.958 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00795 FA-36-VA24_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -5.28285 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6050_KD_PPAN_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08132 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18008 cetuximab_homo sapiens_gpl570_gse21483 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Holliday junction resolvase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.826 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29857 BFTC-905 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.933431 MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0826-SM-3MJFN GTEx Tissue Sample Gene Expression Profiles 1.0 0.981506 CUL3 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC3342315-pone.0036054.s011.xlsx-overlap_PBX1_ChIP_siRNA-Unnamed_5_PBX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-UPK5-0008-SM-4IHJD GTEx Tissue Sample Gene Expression Profiles 1.0 0.912368 H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XV7Q-2126-SM-4BRVX GTEx Tissue Sample Gene Expression Profiles 1.0 0.857456 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.32368 CTCF_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20571 BC-63-DM76_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.396236 POLR2AphosphoS5_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE180185_7_v_1_setbp1_human RummaGEO Gene Perturbation Signatures 1.0 null lateral superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25347 HD-89-HC56_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.410194 CTCF-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A622-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH226 CCLE Cell Line Gene CNV Profiles -1.0 -1.49508 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null retrosplenial cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17624 H3K9ac_Rectal Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-U8XE-0626-SM-3DB8U GTEx Tissue Sample Gene Expression Profiles -1.0 -2.26218 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4UY-0426-SM-3K2AF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32794 FAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07407 POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LB2241-RCC COSMIC Cell Line Gene CNV Profiles 1.0 2.59653 GSE128099,GSE128159_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures -1.0 null Paragigantocellular reticular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49275 CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCARF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06489 GTEX-SE5C-0008-SM-4B64J GTEx Tissue Sample Gene Expression Profiles 1.0 1.16081 H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RELA_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-0008-SM-48TDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.47696 GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08006 H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.9721 ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GA-28-SS67_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.521664 GTEX-QXCU-1926-SM-48FE4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898284 GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles 1.0 1.06491 GP2D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null BC-25-VR48_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.94843 WC-09-GD62_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.72673 GTEX-OXRP-2426-SM-2S1NR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62338 2791_EXOSC4_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.589507 SUZ12_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lobules IV-V, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00364 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE130383_1_v_3_gps2_mouse RummaGEO Gene Perturbation Signatures -1.0 null membrane-enclosed lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.545 GTEX-VUSG-0008-SM-4KL24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46774 POLR2AphosphoS2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE133691_1_v_3_lgr5_mouse RummaGEO Gene Perturbation Signatures -1.0 null WM983B CCLE Cell Line Gene Expression Profiles -1.0 -2.43572 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SIU8-0008-SM-4BRUC GTEx Tissue Sample Gene Expression Profiles 1.0 1.04815 CD-13-QZ32_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.254604 H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF172 CCLE Cell Line Gene CNV Profiles -1.0 -1.65577 ChIP_REST_21632747 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50402 Rectum adenocarcinoma_READ_TCGA-DC-5337-01A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RN64-0526-SM-2TC5P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.888393 496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.04618 FD-62-ZB67_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.56169 CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MO-1926-SM-32QOJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.87863 Perturb_6018_KD_GLTSCR2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.855622 cytoplasmic part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 VA-06-DB75_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.322994 WM-266-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10767 Perturb_6090_KD_YLPM1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 H3K36me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955057 GTEX-S4P3-1826-SM-3K2AL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.976988 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.40515 CEBPB_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VUSG-0626-SM-4KL1Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889279 vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Perturb_6023_KD_HNRNPL_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE126463_4_v_2_pomalidomide_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AB-09-EA37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.673084 POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57122 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64056 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LN-18 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.92 pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.94225 USF2 ENCODE Transcription Factor Targets 1.0 null POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NB-80-IM48_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.63868 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4739 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13318 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null HDAC6 ENCODE Transcription Factor Targets 1.0 null VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13049 H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23401 cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.854186 GMEB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.52414 6611_PPAT_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 1.28782 PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11 Rummagene Transcription Factor Associations 2026 1.0 null anterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.861771 POLR2A_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17642 RAD21_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Q734-1126-SM-48TZY GTEx Tissue Sample Gene Expression Profiles 1.0 1.02446 layer 1 of RSC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43411 SMC3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DB-21-FY75_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.84113 Acute Myeloid Leukemia_LAML_TCGA-AB-2856-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AB-97-BI36_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.246821 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1255 GTEX-QMRM-0008-SM-447B1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04864 JD-44-KF86_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.68557 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spleen GTEx Tissue Gene Expression Profiles 1.0 0.952779 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.37043 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-0011-R9A-SM-4AT45 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12251 FD-91-OK66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -8.2794 GTEX-X88G-0326-SM-47JZ4 GTEx Tissue Sample Gene Expression Profiles 1.0 3.38253 CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null nucleus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27602 NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.15109 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AC-84-QG99_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.206631 DC-51-WE27_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -8.82903 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.929891 JJ012 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.849129 MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.19962 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TPP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61437 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.04083 PBX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.94028 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00846 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1485 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.2373 GTEX-S7PM-0008-SM-3NM9Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.02929 GTEX-XOT4-1426-SM-4B65T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80891 HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.1614 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intracellular organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.545 GTEX-RTLS-0526-SM-2TF64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05144 BB-79-AG41_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.373159 SPI1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null UACC893 CCLE Cell Line Gene CNV Profiles 1.0 1.50955 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.921019 COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.16831 Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNOS-0008-SM-4DM6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.09695 GTEX-UJHI-0226-SM-4IHJL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873971 OF-05-CB18_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.22212 inner SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.920879 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-0426-SM-4DXSE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20099 Perturb_6037_KD_MBNL1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE184892_4_v_1_trehalose_human RummaGEO Drug Perturbation Signatures 1.0 null Organelle lumen COMPARTMENTS Experimental Protein Localization Evidence Scores 2025 1.0 1.545 H3K79me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE183271_4_v_3_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null TPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10315 GTEX-U8XE-0226-SM-4E3J3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.876033 POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2758-01A-02R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.824272 GSE240027,GSE240030_1_v_0_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null BA-84-TD72_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.594333 MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18584 intermediate stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5597 Lung squamous cell carcinoma_LUSC_TCGA-66-2781-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCUM1_STOMACH CCLE Cell Line Proteomics 1.0 2.24917 Ectorhinal area/Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02861 GTEX-OXRP-0526-SM-2I3EW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.936099 GTEX-POMQ-0008-SM-48TE7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.74714 GTEX-OXRL-0326-SM-2I3F2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02087 Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7398 PPP1R3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43475 H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null XE-18-BC97_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.267145 PD-70-VS77_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.881421 KYSE450 CCLE Cell Line Gene Expression Profiles 1.0 1.93603 ID-00-IC14_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.566629 H3K36me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3_OE_GDS3444_576_mouse_Cultured embryonic stem (ES) cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Intraciliary transport particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.982 HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null DD-71-LY65_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.789638 SPI1_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.17468 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.62614 GD-66-XE49_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.362866 EC-82-LV30_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.546909 GSE197850_4_v_3_glucagon_human RummaGEO Drug Perturbation Signatures -1.0 null Mitochondrial ribonuclease P complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.803 CE-15-YU05_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.4101 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYBL2 ENCODE Transcription Factor Targets 1.0 null BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytosol COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 PMC10635891-mmc2.docx-36-KLF3_KLF3 Rummagene Transcription Factor Associations 2026 1.0 null CAPZA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10384 MKN45 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.41337 retrotrapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99129 H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null placenta BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.7253 S0-EE-Y7IR_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.11255 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P44H-1126-SM-48TBU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35276 H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE123638,GSE123639_3_v_1_bortezomib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OIZH-1826-SM-2YUNP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42805 H2BK15ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mediodorsal nucleus of thalamus_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.1946 GSE130246_2_v_3_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null LU65 CCLE Cell Line Gene CNV Profiles 1.0 1.76942 AB-21-VE32_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.304898 AA-62-HP31_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.853512 GTEX-V955-2426-SM-3GAEF GTEx Tissue Sample Gene Expression Profiles 1.0 0.847969 GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40745 Psoas_Muscle Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.07433 GTEX-S33H-2426-SM-2XCB2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03599 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.950174 SETDB1 ChEA Transcription Factor Targets 1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.55403 EF-74-KW12_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.408589 SP in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.962069 GSE154936_3_v_4_remdesivir_human RummaGEO Drug Perturbation Signatures -1.0 null GSE115395_2_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.971563 GTEX-NPJ8-0011-R1a-SM-33HCB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01645 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.90812 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OB-61-XZ91_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.390217 CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PC-62-AQ92_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.25261 PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AA-68-OJ16_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.607438 GSE89154_1_v_3_proscillaridin_human RummaGEO Drug Perturbation Signatures -1.0 null rostral zona incerta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05492 GTEX-P4QR-0726-SM-2I5GO GTEx Tissue Sample Gene Expression Profiles 1.0 1.47455 erg_19359602_huvec_lof_human_gpl570_gds3557 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.039292 BB-86-BE19_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.37203 PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-E18-D3_2440_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE244233_1_v_0_quercetin_human RummaGEO Drug Perturbation Signatures 1.0 null H4K20me1_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null p1 part of the pararubral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0288 BT-474 COSMIC Cell Line Gene CNV Profiles 1.0 2.59653 MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Diffuse large B-cell lymphoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.149 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.45851 GD-79-TW34_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.519205 CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09559 GSE146982_7_v_1_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-371-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 KA-81-AG66_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -4.04896 GTEX-RUSQ-0326-SM-47JWS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34226 NFE2 ENCODE Transcription Factor Targets 1.0 null POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KM12 CCLE Cell Line Gene Expression Profiles 1.0 1.51224 17660535-TableS4a GeneSigDB Published Gene Signatures 1.0 null head of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.95003 MYC ENCODE Transcription Factor Targets 1.0 null SOD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61845 PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_HSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15593 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.957532 AC-30-XU83_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.459358 NCI-H1734 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GTEX-XBED-0726-SM-4GIAR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930729 FU97 CCLE Cell Line Gene CNV Profiles -1.0 -2.03118 CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEWO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.74018 MA-43-MR37_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.700987 CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE120612_4_v_1_etoposide_human RummaGEO Drug Perturbation Signatures 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42962 GTEX-NPJ8-1626-SM-2HMIY GTEx Tissue Sample Gene Expression Profiles 1.0 0.966718 H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49535 dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05424 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.876992 Temporal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15507 GTEX-QDVN-2426-SM-2S1Q4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.939432 Perturb_6071_KD_SLTM_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 CTCF_GM12870_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4_KO_Pabpn1l_SRP226170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.41399 AB-33-EM56_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.14224 GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30115 TP73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29155 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.857542 BD-61-OO16_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.392487 subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01012 GTEX-S7SF-1826-SM-3K2AD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.108 7164_RBM22_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures -1.0 -0.637177 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE127790_4_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-U4B1-1926-SM-3DB9E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.87385 Organum vasculosum laminae terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.649 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.939596 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUW1-0008-SM-4BOQH GTEx Tissue Sample Gene Expression Profiles 1.0 1.00026 GSE131887_1_v_0_doxycycline_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-SNOS-1526-SM-32PLW GTEx Tissue Sample Gene Expression Profiles 1.0 1.20859 TFAP2C_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K79me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TSE9-0426-SM-3DB81 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.833215 E2F1-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08964 Parasubiculum, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.30961 posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.836234 Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG7-0008-SM-4LMKB GTEx Tissue Sample Gene Expression Profiles 1.0 0.892948 Ribonuclease MRP complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 4651_LRP8_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.601078 GSE77108_8_v_2_saha_human RummaGEO Drug Perturbation Signatures -1.0 null CHD1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null skeletal muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE222758_0_v_4_clofazimine_human RummaGEO Drug Perturbation Signatures -1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ERMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16766 H3K36me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cartilage-hair hypoplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.171 tRNA 5'-end processing GO Biological Process Annotations 2025 1.0 null PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XUZC-1426-SM-4BRV3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.994815 H3K79me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.78834 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.4602 Mesothelioma_MESO_TCGA-MQ-A6BN-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT5A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.00027 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K36me3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QCQG-1726-SM-3GIJ9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0814 10623_ZNF774_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures -1.0 -0.566512 KF-18-RY71_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.80554 protein binding GO Molecular Function Annotations 2015 1.0 null Glyoxysome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.931 MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AC-30-XU83_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.265881 bonemarrow_6c HPA Tissue Sample Gene Expression Profiles -1.0 -1.3903 Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.20639 Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HC-01-FD24_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.295827 KA-29-AB08_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.218198 VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37337 GTEX-X4EO-0326-SM-3P5YO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841109 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAP2K4_knockdown_62_GSE19091 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -0.965153 GTEX-W5WG-2226-SM-4LMI3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.99417 GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles 1.0 1.18658 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.93361 POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-0826-SM-32PM4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67687 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.903934 GSE161055,GSE161056_1_v_0_hira_mouse RummaGEO Gene Perturbation Signatures -1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.0576 TCF7L2 ENCODE Transcription Factor Targets 1.0 null GSE159446,GSE159449_1_v_0_tunicamycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XUJ4-2626-SM-4BOQ3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.77788 yy1_20215434_hela_lof_human_gpl570_gds3788 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.08699 BA-95-YU85_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.471355 CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-1538 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 496100336_TCx_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.14135 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-0326-SM-2TF5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29 GSE77108_0_v_2_saha_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-UTHO-2426-SM-4JBHD GTEx Tissue Sample Gene Expression Profiles 1.0 0.874047 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17284 GTEX-WZTO-0426-SM-3NM99 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.09857 dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.08806 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE130396_1_v_6_neratinib_human RummaGEO Drug Perturbation Signatures 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RTLS-0926-SM-2TF5X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.897131 GTEX-WYJK-1726-SM-3NM9U GTEx Tissue Sample Gene Expression Profiles 1.0 1.13931 Anterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20606 FB-49-NW04_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.17403 mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70618 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.936119 basomedial nucleus (accessory basal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.934745 EBF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4274 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 BT474 CCLE Cell Line Gene CNV Profiles 1.0 2.01741 H3K79me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.65415 FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0826-SM-3NM8Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.50233 SUPHD1 CCLE Cell Line Gene CNV Profiles 1.0 1.62364 H3K9ac_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.35616 Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MELK_knockdown_150_GSE32873 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.58254 AA-23-FM46_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.765868 CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LS 174T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23213 hsa-miR-3927 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GE-34-TW62_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.351161 ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WRHU-0226-SM-3MJFV GTEx Tissue Sample Gene Expression Profiles -1.0 -2.11907 skeletalmuscle_b HPA Tissue Sample Gene Expression Profiles 1.0 1.16736 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9933 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5868 GSE231648_0_v_2_lsm14b_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K36me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBED-0008-SM-47JWO GTEx Tissue Sample Gene Expression Profiles 1.0 0.964772 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.885202 POLR2AphosphoS5_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4A-19761587-HUMAN INTESTINAL CELL LINE CACO-2-human ChEA Transcription Factor Binding Site Profiles 1.0 null HDAC2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RN64-0326-SM-2TC5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.4823 superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46331 H3K4me1_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Testis GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.929588 GSE239373_0_v_1_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null 2233_DIS3_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 0.626354 GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.888575 TA-34-CK62_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.50287 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.3919 POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOT4-0526-SM-4B66O GTEx Tissue Sample Gene Expression Profiles 1.0 1.39869 H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-LMS-1 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.72786 nucleus GO Cellular Component Annotations 2015 1.0 null GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles 1.0 2.87587 GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.41658 ELK1 ENCODE Transcription Factor Targets 1.0 null CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01323 PMC11947124-41419_2025_7562_MOESM1_ESM.docx-348-ZFAT_ZFAT Rummagene Transcription Factor Associations 2026 1.0 null Amastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.883 PF-59-CY33_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.818313 YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BA-84-TD72_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.726593 GSE148252_1_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE232786_1_v_0_otud1_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09576 MCM2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46929 CTCF_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22832 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE178714_5_v_7_smad2_human RummaGEO Gene Perturbation Signatures -1.0 null HCC1897 CCLE Cell Line Gene Expression Profiles 1.0 1.60405 NFE2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1 ENCODE Transcription Factor Targets 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972204 Peripheral_Blood_Mononuclear_Primary_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.39348 ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53984 MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1184 SIMA Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.42384 BD-49-MD69_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -9.72389 SARS-dORF6_12Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.10927 QF-71-QI30_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.08303 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-WFON-2526-SM-3LK7P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.866049 intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE147664_0_v_1_arid1b_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null EA-39-YN88_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.256213 MYC_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPL23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04831 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCL2L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11503 SKM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.990266 JD-58-MV19_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.721656 Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r5 part of A5 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51128 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-1626-SM-2TF5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.1338 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.868158 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYJK-0426-SM-3NM9G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63658 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07142 BB-11-JI42_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.383585 GA-88-CF36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.248575 DC-47-KV62_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.268106 BA-84-WN26_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.79285 GA-28-SS67_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.36013 HCC2157 CCLE Cell Line Gene CNV Profiles 1.0 1.57305 AB-33-EM56_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.64072 AC-55-XA97_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.80423 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.838557 r6 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06123 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.71462 DB-21-FY75_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -6.04784 medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.1516 PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-D-Enh_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles 1.0 1.31295 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.85641 H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EE-03-SG02_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.18374 GTEX-QDT8-0526-SM-3NMD8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46975 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21996 CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEC1A CCLE Cell Line Gene CNV Profiles -1.0 -1.32196 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KA-81-AG66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -7.19432 MB-15-ZF03_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.744442 SRF ENCODE Transcription Factor Targets 1.0 null Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16763 WC-16-IR43_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.641981 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.983711 FA-80-DR66_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.30636 H3K36me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.80466 outer SZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.907824 GTEX-QEG4-0008-SM-48TYZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.20712 Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09667 posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.83103 GTEX-SN8G-0001-SM-3NM8L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23352 IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.87967 organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-XV7Q-0126-SM-4BRVK GTEx Tissue Sample Gene Expression Profiles 1.0 0.82833 ribonuclease MRP complex GO Cellular Component Annotations 2023 1.0 null MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PSDG-0226-SM-33HC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909731 NCI-H2347 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.922788 Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SA-03-IQ14_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.273075 caudal zona incerta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07127 PMC6151027-12864_2018_5080_MOESM3_ESM.xlsx-Embryo-Hatchling_1272_AR-DEGs-Symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F4_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.529 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4EO-0926-SM-3P5Z2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2576 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06452 GTEX-U412-0008-SM-4DXTE GTEx Tissue Sample Gene Expression Profiles 1.0 0.867508 GTEX-OXRK-0526-SM-3NB2F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12699 Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-33576154-HUMAN-LIVER-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null FF-86-NH56_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.421455 RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE231891_5_v_4_cdk8_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-1126-SM-4DM71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28916 LP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.21171 BC-54-ON71_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.645375 POU2F2 ENCODE Transcription Factor Targets 1.0 null ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null accessory entopeduncular nucleus (post-migratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5447 wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -1.07234 GTEX-UTHO-0726-SM-3GAEN GTEx Tissue Sample Gene Expression Profiles 1.0 0.985832 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.19885 GTEX-RU1J-1926-SM-2TF6S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36643 GTEX-QLQ7-0008-SM-447AW GTEx Tissue Sample Gene Expression Profiles 1.0 1.00193 SLC30A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1265 FOXA1_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QXCU-0926-SM-48FEP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33723 ventrolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.982919 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10183 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.877022 H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09446 GTEX-V955-0926-SM-4JBJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06469 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.03367 doxorubicin_homo sapiens_gpl570_gse46493 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53859 H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE188570,GSE188571_3_v_1_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF675 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1673 BCLAF1 ENCODE Transcription Factor Targets 1.0 null GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles 1.0 0.948475 DC-51-WE27_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.53237 H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R53T-2026-SM-3GIJF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30486 MAZ_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DC-51-WE27_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.32258 H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PSDG-1126-SM-2S1ON GTEx Tissue Sample Gene Expression Profiles -1.0 -0.905112 7754_SEC62_P1P2 Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures 1.0 1.40066 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23977 ZNF384 ENCODE Transcription Factor Targets 1.0 null GTEX-S4Z8-0626-SM-4AD6J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961503 H3K4me1_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CTCF_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SF-1626-SM-3K2AY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.90772 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874665 GSE182179_0_v_4_kdsr_human RummaGEO Gene Perturbation Signatures -1.0 null GSE219274,GSE219276_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40153 ABHD16B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40664 H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null KB-92-MK13_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.431976 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.991424 intermediate stratum of r6Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00121 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3304 GSE112763,GSE112767_4_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null HCC1500 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.79502 CDK7_knockdown_138_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -3.18196 endometrium_8b HPA Tissue Sample Gene Expression Profiles -1.0 -1.73671 H3K36me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZH-1626-SM-2HMKI GTEx Tissue Sample Gene Expression Profiles 1.0 0.930232 NOMO-1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.594 CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06236 GSE186287_1_v_3_ufm1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-QEG5-1126-SM-33HC2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.865966 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null sno(s)RNA-containing ribonucleoprotein complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 CHEK1_knockdown_136_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.25431 GSE57871_11_v_12_vorinostat_human RummaGEO Drug Perturbation Signatures -1.0 null EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NARF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21043 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.13335 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YD-49-HM53_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.235 Metabolite levels GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.522185 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.93861 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null smoothmuscle_8b HPA Tissue Sample Gene Expression Profiles -1.0 -0.908909 Mono-Mac-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.944 CC-68-YZ44_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.430568 outer SZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01683 CC-17-JL38_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -7.75281 H3K36me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEL4-0526-SM-3GIJ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28709 GSE146074_10_v_3_ly6e_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CD-35-BD44_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.567812 RASSF8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.04097 POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_K562_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null rhombomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41157 Brain Lower Grade Glioma_LGG_TCGA-CS-4944-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MXI1_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null Z chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.636 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CA-68-KG29_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.945471 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null ATP6V1D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12517 Abscission zone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.147 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE254517_1_v_0_irf7_mouse RummaGEO Gene Perturbation Signatures 1.0 null KNS-62 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.71139 amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11433 MRPS5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4796 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.864858 GTEX-UJMC-1826-SM-3GADT GTEx Tissue Sample Gene Expression Profiles 1.0 1.61488 GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles 1.0 0.881797 anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25272 H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X8HC-0226-SM-4E3K1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.927438 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CA-68-KG29_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.348588 GTEX-RNOR-0526-SM-2TF4O GTEx Tissue Sample Gene Expression Profiles 1.0 1.01294 GTEX-PWOO-2426-SM-2S1OV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10061 CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33314 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0115 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K36me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ED-05-LQ40_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.02021 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45426 INO80E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03699 496100330_PCx_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03094 GTEX-RU1J-0426-SM-46MUK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00443 H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null SKHEP1 CCLE Cell Line Gene Expression Profiles -1.0 -1.49426 mantle zone of r7Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23194 H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100613_TCx_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.48787 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.914507 2932_RIPOR1_P1 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.735259 GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles 1.0 2.03004 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LY-01A-31R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE124410_2_v_4_stk40_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner SZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825856 Artery - Aorta GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.03102 GTEX-NFK9-0626-SM-2HMIV GTEx Tissue Sample Gene Expression Profiles 1.0 1.9163 RAD21 ChEA Transcription Factor Targets 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE186620_0_v_1_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_SK-N-SH_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null KA-29-AB08_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -5.02579 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZN-0008-SM-4DXTL GTEx Tissue Sample Gene Expression Profiles 1.0 0.929864 JE-72-KV75_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.83234 16203795-Table2 GeneSigDB Published Gene Signatures 1.0 null H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null LAMA-84 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.684 H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12892_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCFC1 ENCODE Transcription Factor Targets 1.0 null CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03513 GTEX-WFG7-2226-SM-3GIKP GTEx Tissue Sample Gene Expression Profiles 1.0 1.94001 Female accessory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.592 hsa-miR-3714 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 FE-82-WB22_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.83109 GSE227127_1_v_0_diclofenac_human RummaGEO Drug Perturbation Signatures -1.0 null fasciola cinerea Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.31777 NCIH23 CCLE Cell Line Gene CNV Profiles 1.0 1.51105 TK-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58681 Perturb_6041_KD_MYBBP1A_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 r8 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16412 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXP2_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SCC-9 COSMIC Cell Line Gene CNV Profiles 1.0 2.59653 GTEX-U3ZH-1726-SM-3DB79 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.07357 Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55E-0526-SM-2TC6B GTEx Tissue Sample Gene Expression Profiles 1.0 1.42509 H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH1693_LUNG CCLE Cell Line Proteomics 1.0 2.24335 Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32687 FOXO3-22982991-MACROPHAGES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null salivary gland HPA Tissue Protein Expression Profiles 1.0 0.776627 posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.862548 tRNA 5'-end processing GO Biological Process Annotations 2023 1.0 null organelle GO Cellular Component Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1 ENCODE Transcription Factor Targets 1.0 null GSE205976,GSE205978_1_v_4_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07779 BB-20-UU03_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.36584 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58805 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 7516_RPS27A_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.722319 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14956 GSE165704_0_v_1_rif1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K36me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC11239565-uxae032_suppl_supplementary_data_s1.pdf-5-ZNF76_ZNF76 Rummagene Transcription Factor Associations 2026 1.0 null shsy5y HPA Cell Line Gene Expression Profiles -1.0 -1.60596 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.842211 Lung squamous cell carcinoma_LUSC_TCGA-37-4133-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ribonuclease MRP complex GO Cellular Component Annotations 2025 1.0 null SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QV44-2026-SM-2S1RD GTEx Tissue Sample Gene Expression Profiles 1.0 1.42175 DB-54-GQ68_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.17279 GTEX-X4XY-0011-R8A-SM-46MVC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20579 H3K23ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37673 Lung adenocarcinoma_LUAD_TCGA-50-5066-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE57871_1_v_2_vorinostat_human RummaGEO Drug Perturbation Signatures -1.0 null dorsolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.869434 H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null XPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46646 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QV31-0008-SM-447AT GTEx Tissue Sample Gene Expression Profiles 1.0 0.966643 496100412_FWM_possible Alzheimer's disease_TBI_87_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.07106 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.861795 Perturb_6030_KD_LLPH_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null rostral ventrolateral reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.13671 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XC-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BA-59-EN38_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.29807 EGR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.980244 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99276 Lung squamous cell carcinoma_LUSC_TCGA-77-8128-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R3RS-0526-SM-3GADG GTEx Tissue Sample Gene Expression Profiles 1.0 0.960256 JD-44-KF86_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.433181 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NOP53 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.5078 primary motor cortex (area M1, area 4)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.86594 SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XPT6-2226-SM-4B66R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850266 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Mesothelioma_MESO_TCGA-SH-A7BD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 2140_DEDD2_P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.523494 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57073 Ventral posterolateral nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23044 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE255432_7_v_0_imeglimin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE220520_6_v_9_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JB-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QXCU-1726-SM-2TC6L GTEx Tissue Sample Gene Expression Profiles 1.0 1.18768 MET_knockout_252_GSE30651 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.63061 POLR2AphosphoS5_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BC-40-TU13_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -2.52585 AA-86-YY62_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.279356 Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHWD-2426-SM-3LK6S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95552 GTEX-NPJ7-0006-SM-3GACR GTEx Tissue Sample Gene Expression Profiles 1.0 0.845511 TBP ENCODE Transcription Factor Targets 1.0 null KA-75-LP02_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -6.47627 GSE148200_0_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures -1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.27157 RELA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.0 pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.611185 USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35798 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.00605 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCL3 ENCODE Transcription Factor Targets 1.0 null 7522_RPS2_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.527101 GSE222758_0_v_1_clofazimine_human RummaGEO Drug Perturbation Signatures -1.0 null PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.874665 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00887 POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anauxetic dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.327 CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE208096_1_v_0_progesterone_mouse RummaGEO Drug Perturbation Signatures 1.0 null UM-UC-3 Sanger Dependency Map Cancer Cell Line Proteomics 1.0 1.57272 Glycosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.642 H3K27ac_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2279 CCLE Cell Line Gene CNV Profiles -1.0 -2.12044 Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BA-95-YU85_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.617477 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE166783_8_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FC-20-EQ58_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.641119 mRNA_SOX17_20123909 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null HNF4A ChEA Transcription Factor Targets 1.0 null Endoribonuclease complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 H3K79me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null BA-68-FJ41_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.38606 G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.92353 HCC1419 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.902822 medial parabrachial nucleus,right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.911456 POLR2A_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SPACA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57738 cerebellar cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.43679 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35745 HDQ-P1 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -3.2775 SNU886 CCLE Cell Line Gene CNV Profiles -1.0 -2.24742 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.46365 GSE166317_3_v_0_j147_mouse RummaGEO Drug Perturbation Signatures -1.0 null FOXA1 ENCODE Transcription Factor Targets 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 12036940-Table2 GeneSigDB Published Gene Signatures 1.0 null GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Brain - Cerebellum GTEx Tissue Gene Expression Profiles 2023 -1.0 -1.26412 YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.929367 YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null binding GO Molecular Function Annotations 2015 1.0 null TAF7 ENCODE Transcription Factor Targets 1.0 null IC-76-JU42_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.246805 trim28_23493425_cd71pluster119plus_sorted_from_bone_marrow_lof_mouse_gpl6887_gse44063 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.978706 GC-04-UF36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.365649 GTEX-QDVN-1326-SM-48TZ3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.832458 FERD3L JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.7684 H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null bonemarrow_5a HPA Tissue Sample Gene Expression Profiles -1.0 -2.58333 OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19118 mantle zone of ZIC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05363 hsa-miR-124-3p MiRTarBase microRNA Targets 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null GSE135514_2_v_3_dasatinib_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-Q2AI-1126-SM-48U19 GTEx Tissue Sample Gene Expression Profiles 1.0 0.870599 BT-474 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.43305 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles 1.0 1.73549 NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.56252 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DA-40-HO94_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.239837 UTP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90841 intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46844 hsa-miR-4745-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 AA-68-OJ16_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.41251 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.996667 GTEX-WFG8-2426-SM-3GILL GTEx Tissue Sample Gene Expression Profiles 1.0 1.15658 H3K27ac_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE195568_3_v_7_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6954 MZ in posterodorsal (superior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15162 FAM221A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4969 JAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.16874 WRNIP1 ENCODE Transcription Factor Targets 1.0 null COR-L23 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.2935 GE-47-OO30_0.01uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.69761 Perturb_6062_KD_RELA_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 NUBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15462 TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null GSE197564,GSE198513_2_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.863784 GSE112763,GSE112767_4_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234340_4_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-U4B1-1626-SM-3DB8N GTEx Tissue Sample Gene Expression Profiles 1.0 0.933296 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null SGCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16559 CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypopharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.698 DKMG CCLE Cell Line Gene Expression Profiles -1.0 -2.13897 ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSE235516_0_v_1_zdhhc2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE142210_9_v_8_panobinostat_human RummaGEO Drug Perturbation Signatures -1.0 null CB-31-UO16_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.40385 intermediate stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04353 CTCF_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09576 CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03501 GNAI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29715 WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.473 PMC10117100-msphere.00056-23-s0008.xlsx-2B-Supplementary_Table_S2B_mRNAseq_analysis_genes_significantely_downregulated_upon_E2F4-5_knockdown_in_38HK_E2F4 Rummagene Transcription Factor Associations 2026 1.0 null MAP2K1_knockdown_134_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.95053 HS852T CCLE Cell Line Gene CNV Profiles -1.0 -1.78114 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FD-62-ZB67_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.66905 r9 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5597 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.912514 H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.8526 SHSY5Y CCLE Cell Line Gene Expression Profiles -1.0 -1.81691 GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.01136 TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FF-28-ES17_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.361872 ELF1-20517297-JURKAT-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Mouth floor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.59 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53955 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null JE-55-OJ53_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.339996 Perturb_6075_KD_SUV39H2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE48812_3_v_1_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null GSE158853_0_v_1_hmgcs2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WYVS-2326-SM-3NMAI GTEx Tissue Sample Gene Expression Profiles 1.0 1.33918 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Ribonucleoprotein complex COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 NCIH2452 CCLE Cell Line Gene Expression Profiles -1.0 -1.53594 H3K36me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.8156 CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r8 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36614 liminal part of the r6 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80468 primary auditory cortex (core)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.52031 RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE95077_5_v_3_amiloride_human RummaGEO Drug Perturbation Signatures -1.0 null HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.878052 POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null DB-21-FY75_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.262388 H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GPX7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31464 UBTF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE105173,GSE105175_1_v_0_dhx36_human RummaGEO Gene Perturbation Signatures -1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null GTEX-OIZF-1526-SM-3MJGY GTEx Tissue Sample Gene Expression Profiles 1.0 0.95901 CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2452 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.35336 Lobules IV-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02082 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A51X-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09274 GSE48812_11_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE121198,GSE129779_3_v_2_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null JA-23-QE71_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.444123 GABPA ENCODE Transcription Factor Targets 1.0 null GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.61858 GSE201239_3_v_4_fmr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR Rummagene Transcription Factor Associations 2026 1.0 null placenta HPA Tissue Protein Expression Profiles 1.0 0.776627 BD-49-MD69_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -1.92903 PB-09-OE00_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.908465 FA-89-PW29_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.39126 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null VD-88-MW70_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.70499 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.991576 EGR1 ENCODE Transcription Factor Targets 1.0 null GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16389 Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09898 PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XUZC-2026-SM-4BRW9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12503 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.90112 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22455 H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55C-1826-SM-3GADI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71783 Adult_Liver Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.23104 JIYOYE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.38426 Lung squamous cell carcinoma_LUSC_TCGA-92-8064-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU5F1 ChEA Transcription Factor Targets 1.0 null DA-07-LL18_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 1.07232 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39Z-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null esophagus HPA Tissue Protein Expression Profiles 1.0 0.776627 Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTGIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25968 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.925202 GSE48812_2_v_10_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFM19 CCLE Cell Line Gene CNV Profiles 1.0 1.56429 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2579 pancreas BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.64136 GTEX-RTLS-0426-SM-2TF5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08002 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00285 GTEX-OIZI-0626-SM-2XCEH GTEx Tissue Sample Gene Expression Profiles 1.0 1.04888 CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-188-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE191037_0_v_1_itraconazole_human RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00631 KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.955057 TPRKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01131 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XBEC-0326-SM-4AT4M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08479 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7870-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB10 Sanger Dependency Map Cancer Cell Line Proteomics -1.0 -2.65857 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27602 H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null REL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.0 ZNF320 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 182.187 FOXA2 ENCODE Transcription Factor Targets 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18414 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GI-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-1426-SM-3DB8Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.965004 GSE57871_1_v_12_vorinostat_human RummaGEO Drug Perturbation Signatures -1.0 null 10455_ZNF567_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures 1.0 0.608111 SNU1076 CCLE Cell Line Gene CNV Profiles 1.0 2.35361 CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ANLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45478 AD-06-OB47_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.4424 MAPK1_knockdown_131_GSE31534 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.88056 Spleen Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.949597 GSE159893_2_v_0_genistein_human RummaGEO Drug Perturbation Signatures 1.0 null RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXM1 ENCODE Transcription Factor Targets 1.0 null GTEX-WRHK-1626-SM-3MJFH GTEx Tissue Sample Gene Expression Profiles 1.0 1.26723 Entorhinal area, medial part, dorsal zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05471 primary auditory cortex (core)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14574 CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.894747 TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02879 CC-61-HH09_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.221823 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NE-20-WM78_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -3.46843 Cement gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.811 GSE143212_0_v_3_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-OOBJ-1626-SM-2I3F7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61759 periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55897 Rad51B-Rad51C-Rad51D-XRCC2 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.528 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67F-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE221327_10_v_9_clpp_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RNOR-0826-SM-2TF5C GTEx Tissue Sample Gene Expression Profiles 1.0 0.833332 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null JC-06-ED36_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.286694 GTEX-OOBJ-0008-SM-3NB26 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31445 RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 7608_RUVBL2_P1P2 Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures -1.0 -0.500005 Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16763 DA-35-DU85_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.976999 Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE154940_1_v_0_nbdy_mouse RummaGEO Gene Perturbation Signatures 1.0 null HE-16-PO98_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.245099 Uterine Carcinosarcoma_UCS_TCGA-N8-A4PM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_CD4 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.27598 BRAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.85504 superficial stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41499 REST ENCODE Transcription Factor Targets 1.0 null Root quiescent center TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.827 SARS-BatSRBD_0Hour_23935999_GSE47960 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.84453 RELA ENCODE Transcription Factor Targets 1.0 null DA-35-DU85_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.731724 principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.913097 KBM-7 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.018 Perturb_4320_KO_Fmn2_SRP109283 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.67171 Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE240027,GSE240030_5_v_2_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles 1.0 0.836183 JUND ENCODE Transcription Factor Targets 1.0 null YY1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYOG_myocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-0426-SM-447A7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09079 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.92353 Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6084_KD_UTP3_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GSE200673,GSE200691_1_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-S3XE-0226-SM-4AD6I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.85273 GTEX-PWCY-0008-SM-48TE9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.979542 GSE199255,GSE199356_4_v_1_pds5a_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X62O-1626-SM-46MW9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22238 H3K36me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HE-80-BQ08_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.776358 Rootlet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.237 TAL1_megakaryocyte_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.901013 primary auditory cortex (core)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.834809 POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null H3K79me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-A539-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06123 Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.789 transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.825119 Subfornical organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.101 POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.37683 AB-74-VK99_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles 1.0 0.211052