association	dataset	threshold value	standardized value
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11131
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.850245
SARS-BatSRBD_84Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.2991
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1702
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LC-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8862
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2303
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1325
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_symbol_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.069
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3704
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA6-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18385
adipose tissue phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Eye cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16872
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.906576
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.46289
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04439
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.972457
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93292
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02283
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.6618
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5152
PMC4219345-1471-2121-14-52-S4.xlsx-BORIS_6dN-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
posttranscriptional	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.907408
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00625
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SYK_druginhibition_155_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.14062
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27692
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.764
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86161
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.894199
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051586
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5655
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF3	ChEA Transcription Factor Targets	1.0	null
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75246
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075385
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
IL4	MSigDB Cancer Gene Co-expression Modules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sodium channel regulator activity	GO Molecular Function Annotations 2023	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70568
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47356
Lung adenocarcinoma_LUAD_TCGA-91-6848-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054003
GSE253579_1_v_0_sectm1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151782_2_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1650	GDSC Cell Line Gene Expression Profiles	1.0	2.07867
Osmotic diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Lung squamous cell carcinoma_LUSC_TCGA-33-4532-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	2.45425
PMC10199266-mmc2.xlsx-RUNX1-DEGs-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.536
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7402
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.763
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913438
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13772
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.239
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.891
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.4129
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2944
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7454
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25993
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9789
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3711
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.397
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865996
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.1361
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4742-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58372
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30472
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5469
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
EZH2	ENCODE Transcription Factor Targets	1.0	null
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1526
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7399
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8133
Lung squamous cell carcinoma_LUSC_TCGA-85-7843-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59945
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8679
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3002
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39948
GSE198036,GSE198041_0_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916223
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47663
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27502
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15276
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5048
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36191
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1522
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2339
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65465
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.826202
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.23106
KNS42	DepMap CRISPR Gene Dependency	1.0	2.12171
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	1.93424
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.882882
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169617_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86171
HT	GDSC Cell Line Gene Expression Profiles	1.0	1.585
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KPNRTBM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61274
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11394
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21598
Portal Hypertension	DisGeNET Gene-Disease Associations	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51042
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888431
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23833
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Atypical Rett syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JY-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991691
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23889
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04404
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25294
Retinoblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.368
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04235
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.936677
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2218
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.55549
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918717
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04994
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73366
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.839197
SUPT3H	MSigDB Cancer Gene Co-expression Modules	1.0	null
regulation of Golgi to plasma membrane protein transport	GO Biological Process Annotations 2023	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0876
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51667
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1523
sensory organ development	GO Biological Process Annotations 2025	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17366
CHP212	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96458
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927966
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23214
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4226
PMC6122955-elife-33947-supp2.xlsx-NY8_v_NY15_DE_Bru-seq-HNF1A-regulated_genes_Bru-seq_after_shRNA_in_NY8_or_NY15_cells_-_related_to_Figure_7A_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE85302_4_v_1_kat6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	4.02079
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10397
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.191097
FSHR	MSigDB Cancer Gene Co-expression Modules	1.0	null
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08894
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43932
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15254
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.3288
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19692
NCIH1563	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5419
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27403
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05688
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25063
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4507
Sarcoma_SARC_TCGA-DX-A6YV-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19393
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.54428
EFE184	CCLE Cell Line Gene CNV Profiles	1.0	1.61442
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.985389
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04689
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07814
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4971
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
release	GeneRIF Biological Term Annotations	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947194
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965381
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35532
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45208
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.26397
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.152
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18494
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08352
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14601
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061984
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20639
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22211
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06818
NFYB-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3382-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7323
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HQ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03543
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65165
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8608
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0693
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865903
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04689
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSB	MSigDB Cancer Gene Co-expression Modules	1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.94983
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.37494
GSE220520_1_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.69107
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
abnormal sterol level	MPO Gene-Phenotype Associations	1.0	null
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967742
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45295
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3059
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2766
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3331-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
A3-KAW	GDSC Cell Line Gene Expression Profiles	1.0	2.63239
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1437
GSE183316,GSE183317_4_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58306
NOS2	MSigDB Cancer Gene Co-expression Modules	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHP126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79105
protein-kinase-c	Phosphosite Textmining Biological Term Annotations	1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
Prostate adenocarcinoma_PRAD_TCGA-HC-7748-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39488
H3K36me3_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4502
Rectum adenocarcinoma_READ_TCGA-F5-6571-01A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.4292
GSE183316,GSE183317_3_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE201042_6_v_0_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13914
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83702
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894787
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01926
hoct2	GeneRIF Biological Term Annotations	1.0	null
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4139
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.951702
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.36834
Brain Lower Grade Glioma_LGG_TCGA-DU-7298-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Golgi apparatus subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.734
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28421
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00079
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5593
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08278
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.00312
negative regulation of Golgi to plasma membrane protein transport	GO Biological Process Annotations 2023	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7922-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060131
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37797
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840943
EGI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.954685
GSE133213_9_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
12036939-Table3	GeneSigDB Published Gene Signatures	1.0	null
H3K36me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18092
increased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37768
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6619
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967742
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9926
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5618
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.960916
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4354
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888431
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22761
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.53946
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DMPK	MSigDB Cancer Gene Co-expression Modules	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Lobule II, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60997
hrs1	GeneRIF Biological Term Annotations	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052516
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23181
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0401
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0678
CRCGN009_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80538
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33861
GSE174383_4_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6028
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6221
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4634
Prostate adenocarcinoma_PRAD_TCGA-HC-7212-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2321
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
obese	MGI Mouse Phenotype Associations 2023	1.0	null
increased body size	MPO Gene-Phenotype Associations	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.78587
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	7.17909
Foxf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2483
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04439
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8133
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2617
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.4747
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.847557
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48154
Tapetum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.573
CBX2-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7144
8-MG-BA	GDSC Cell Line Gene Expression Profiles	1.0	1.59805
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067681
Epileptic encephalopathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.583
oocytes	GeneRIF Biological Term Annotations	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.9647
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Paragigantocellular reticular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15916
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
caco-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295655
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.9806
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-SKI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3289
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.99501
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33955
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.07911
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24066
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.98148
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SLVL	DepMap CRISPR Gene Dependency	1.0	7.51845
regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345928
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1759
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02716
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17499
sf-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.543359
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953652
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5902
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.869724
GSE144231_3_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74818
negative regulation of transport	GO Biological Process Annotations 2025	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39741
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.478
abnormal energy homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.591
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9942
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5277-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7611259-EMS114661-supplement-Supplementary_Tables.xlsx-ST18-Unnamed_9_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10115638-41591_2023_2255_MOESM4_ESM.xlsx-CNS_NB_FOXR2_deletions-Unnamed_2_FOXR2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN012_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13287
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00738
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20008
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PCGF4-22325352-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4872
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.866842
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7594-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4897
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4134
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6435
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35734
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5143
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.6457
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23881
increased fat cell size	MGI Mouse Phenotype Associations 2023	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
cellular process	GO Biological Process Annotations 2015	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88859
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71523
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4698
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
17952126-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0227
EM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49728
GSE174383_4_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7053
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.857806
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06246
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44755
Nonpigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
PMC12522211-NIHMS2104691-supplement-MMC1.xlsx-SRCAP_DE_genes-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06978
Lung squamous cell carcinoma_LUSC_TCGA-90-7766-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135784
NCIH23	DepMap CRISPR Gene Dependency	1.0	2.77667
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75214
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
increased percent body fat/body weight	MGI Mouse Phenotype Associations 2023	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48935
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8787
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26297
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08173
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02228
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4725-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8713
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.56224
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887489
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3385
SNU81	DepMap CRISPR Gene Dependency	1.0	3.16284
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00054
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18406
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051799
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055607
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827828
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0939
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.239
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0843
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2012
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3096
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3645
BALL-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47676
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703536
dexamethasone_mus musculus_gpl6105_gse44208	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	3.18885
pkc	Phosphosite Textmining Biological Term Annotations	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.9737
MAZ_02_199	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58798
Epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05663
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22211
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4263
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8276
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.3609
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838417
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1645
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4336
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10157
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866137
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC11	DepMap CRISPR Gene Dependency	1.0	4.76
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.0024
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95244
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.582
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0636
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42076
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28414
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.671
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5861
Interstitial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8584
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873501
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910161
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
neuron to neuron synapse	GO Cellular Component Annotations 2025	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7789
GSK3A_KD_GDS4305_178_human_HL-60 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
aromatic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32181
SIMA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70989
Intestinal hexose absorption	Reactome Pathways 2024	1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2959
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33473
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12434
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44686
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Angelman syndrome-like	ClinVar Gene-Phenotype Associations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7368-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041436
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.74
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927966
metabolic process	GO Biological Process Annotations 2015	1.0	null
GSK3B_KD_GDS4305_179_human_HL-60 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
West syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04038
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49266
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1873
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8586
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	1.7569
increased body weight	MPO Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.956762
Alcoholic chronic pancreatitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.752288
HH	CCLE Cell Line Gene CNV Profiles	1.0	1.43459
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
negative regulation of Golgi to plasma membrane protein transport	GO Biological Process Annotations 2025	1.0	null
Alcoholic pancreatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
liver	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
abnormal water content	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2696-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4615
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Down_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235066_4_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5745
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.58595
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999233
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25865
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal food intake	MPO Gene-Phenotype Associations	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80706
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.265
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49091
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16693
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11356
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.50829
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32177
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Photoreceptor inner segment membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.683
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97129
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05395
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868365
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1419	DepMap CRISPR Gene Dependency	1.0	2.18286
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976357
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25213
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82727
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5806
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Interphotoreceptor matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37301
IGR-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57973
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074736
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Supplementary_Table_2C_Contrast_ATF4-def_DMSO_8h_vs_HCT116_DMSO_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45236
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.23391
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3915
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119808
GSE160817_4_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.07348
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6258
increased circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10521
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.517
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
negative regulation of protein localization to membrane	GO Biological Process Annotations 2025	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23928
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0469
abnormal digestive system physiology	MPO Gene-Phenotype Associations	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.21286
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85045
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13165
glucosedependent	GeneRIF Biological Term Annotations	1.0	null
Liver epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4098
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05127
SNUC1	DepMap CRISPR Gene Dependency	1.0	2.55231
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23641
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56718
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33991
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.939313
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8647
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45976
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44O-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01352
SK-MEL-28	GDSC Cell Line Gene Expression Profiles	1.0	1.62838
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.228
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878632
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03031
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10945
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73D-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
KDM5A	ENCODE Transcription Factor Targets	1.0	null
NOS-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.858253
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.731
regulation of localization	GO Biological Process Annotations 2015	1.0	null
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1948
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07785
Cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G6-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12146
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6873
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196505,GSE196507_3_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13091
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30508
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79244
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of nucleoside transport	GO Biological Process Annotations 2025	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999933
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50587
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.878365
golgi	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.566
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068675
GSE242199_2_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9021
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1935
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055841
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-144	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85647
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.339282
Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3858
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.189
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4729482-pone.0146505.s004.xlsx-Sheet1-AR_associated_genes_identified_in_ccRCC_not_pRCC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2747
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8642
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4232
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63928
increased circulating cholesterol level	MGI Mouse Phenotype Associations 2023	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9018
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061634
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053951
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.089835
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43968
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34397
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00407
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045401
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	1.37313
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33866
prostate	HPA Tissue Protein Expression Profiles	1.0	1.69107
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1948
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07783
MLLT10	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2609
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.6766
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.20668
Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	GO Cellular Component Annotations 2015	1.0	null
CRCGN013_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64752
golgi apparatus	GO Cellular Component Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10386
SNU16	DepMap CRISPR Gene Dependency	1.0	9.81709
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	77.3562
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.00312
GATA6-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54164
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.941718
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.951588
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5763
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.111
Photoreceptor inner segment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7059
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041815
tRNA-intron endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3587
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6239
Arciform density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.736571
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24953
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.076
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22211
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052412
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16693
SOX4-29892750-EML-MOUSE-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
Jejunal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Side of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
SESN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93288
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.71717
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34176
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993919
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.3711
Lobule III	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70132
shuttling	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37318
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.436
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.102
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7897
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3994
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9613
foxa1_23539448_lncap_lof_human_gpl10558_gse37314	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.585887
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0155
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13975
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06739
GSE241036_4_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45582
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.38809
H3K36me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8062
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062205
ZNF229	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4337
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985431
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7DS-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01215
LXF-289	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44023
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5347
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2964
SK-CO-1	GDSC Cell Line Gene Expression Profiles	-1.0	-3.53652
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
abnormal percent body fat	MPO Gene-Phenotype Associations	1.0	null
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7667
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2389
abnormal carbohydrate absorption	MPO Gene-Phenotype Associations	1.0	null
IMR32	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07001
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.0941
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08332
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A185-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SR	GDSC Cell Line Gene Expression Profiles	-1.0	-2.33072
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.4635
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38206
TCF3-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.874
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3036
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20288
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56418
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.628
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.902505
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-1.28365
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09311
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.93608
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222224
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42617
organic cyclic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.27205
MYB-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5252
HEC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.57009
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42702
negative regulation of transmembrane transport	GO Biological Process Annotations 2025	1.0	null
GSE123836_2_v_0_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cornea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.667
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77397
Photoreceptor outer segment membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.023
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927966
Brain Lower Grade Glioma_LGG_TCGA-HT-8106-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34216
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877572
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1563
MC-CAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069759
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76893
GSE151782_4_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977216
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06466
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.990945
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0172
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10392
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.82123
increased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.19431
ATF2	MSigDB Cancer Gene Co-expression Modules	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9466
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78641
Liver Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.50221
KPNSI9S	CCLE Cell Line Gene CNV Profiles	-1.0	-3.19765
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.827018
GSE220287_2_v_1_mef2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75635
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.347
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5207
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06975
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918717
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829693
negative regulation of nucleoside transport	GO Biological Process Annotations 2023	1.0	null
membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
u87	HPA Cell Line Gene Expression Profiles	-1.0	-0.923521
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2526
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00681
Lung adenocarcinoma_LUAD_TCGA-78-7155-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inhibiting	GeneRIF Biological Term Annotations	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.29201
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047132
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-7848-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7964-01A-21R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.18123
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040952
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04649
PANC1	DepMap CRISPR Gene Dependency	1.0	2.34371
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.9223
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051514
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0531
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3048
cycle-dependent	Phosphosite Textmining Biological Term Annotations	1.0	null
SNU626	DepMap CRISPR Gene Dependency	1.0	2.17873
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_downregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal	Phosphosite Textmining Biological Term Annotations	1.0	null
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.556
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.589
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44Q-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVSAT	CCLE Cell Line Gene CNV Profiles	1.0	1.39874
H3K36me3_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ca2+	Phosphosite Textmining Biological Term Annotations	1.0	null
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Digestion and absorption	Reactome Pathways 2024	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9397
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12954
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49505
Small intestine cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
H3K36me3_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4581
H3K36me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
p95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96023
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96371
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1944	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57885
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62644
RAD51D	MSigDB Cancer Gene Co-expression Modules	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
swine	Phosphosite Textmining Biological Term Annotations	1.0	null
MET_knockout_250_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.97051
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899764
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048637
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37542
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.775
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.84634
trans-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.76
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7357
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89039
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27064
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.03345
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.49
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.452
protein complex oligomerization	GO Biological Process Annotations 2025	1.0	null
negative regulation of protein localization to plasma membrane	GO Biological Process Annotations 2025	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased intestinal glucose absorption	MGI Mouse Phenotype Associations 2023	1.0	null
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal food intake	MGI Mouse Phenotype Associations 2023	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3392
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15022
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.888164
HNFA-21074721-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64189
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967596
NOS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.78461
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.8408
H3K36me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lobule III, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68684
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE166767_1_v_2_ctcfl_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31485
NOMO-1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61893
H3K36me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Presynaptic periactive zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
H3K36me3_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocycle biosynthetic process	GO Biological Process Annotations 2015	1.0	null
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877217
Frontal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.58
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4637
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal hormone level	MPO Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.56462
hsglt1	GeneRIF Biological Term Annotations	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03062
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048833
negative regulation of protein localization to cell periphery	GO Biological Process Annotations 2023	1.0	null
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4371
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.8497
Prostate adenocarcinoma_PRAD_TCGA-EJ-5530-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0496
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	2.13535
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15189
abnormal energy homeostasis	MPO Gene-Phenotype Associations	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-6178-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862745
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2537
SSR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39625
negative regulation of transport	GO Biological Process Annotations 2015	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927966
abnormal cholesterol homeostasis	MPO Gene-Phenotype Associations	1.0	null
16151515-TableS6	GeneSigDB Published Gene Signatures	1.0	null
ZNF180_02_177	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.88296
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.0626
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80784
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28714
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73359
Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EVSAT	DepMap CRISPR Gene Dependency	1.0	2.36036
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14834
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52528
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83659
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931681
SOX2	ChEA Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04112
negative regulation of glucose transmembrane transport	GO Biological Process Annotations 2023	1.0	null
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3539
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE242199_6_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26397
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAGEA8	MSigDB Cancer Gene Co-expression Modules	1.0	null
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	52.9515
NCIH1836	DepMap CRISPR Gene Dependency	1.0	3.93792
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58932
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.933752
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	6.45155
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7143
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8705
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4959
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5636
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial geniculate complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42813
membrane	GO Cellular Component Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6206-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5526
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0373
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13884
SUPT11	CCLE Cell Line Gene CNV Profiles	1.0	1.61027
Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83635
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39828
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3821
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29M-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
calcium-calmodulin-dependent-protein-kinases	Phosphosite Textmining Biological Term Annotations	1.0	null
LN319	DepMap CRISPR Gene Dependency	1.0	2.38463
protein homooligomerization	GO Biological Process Annotations 2025	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859231
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.103
abnormal circulating leptin level	MPO Gene-Phenotype Associations	1.0	null
INA6	DepMap CRISPR Gene Dependency	1.0	2.37564
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.60913
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.471
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08022
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5145
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26763
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83835
GSE230354_0_v_1_rheb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979077
g2/m	Phosphosite Textmining Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4798
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-2.39936
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1276
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.22804
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8795
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15659
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44148
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KP-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
222 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49582
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9192
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3561
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
transcriptional	GeneRIF Biological Term Annotations	1.0	null
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11635
together	GeneRIF Biological Term Annotations	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1997
GSE201042_6_v_10_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell wall-bounded periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5617
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8088
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFNA1	MSigDB Cancer Gene Co-expression Modules	1.0	null
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.08136
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
increased circulating leptin level	MGI Mouse Phenotype Associations 2023	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04216
Brain Lower Grade Glioma_LGG_TCGA-HT-8563-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5511-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07507
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23941
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05275
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9773
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9669
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19827
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1824
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.706
SAP30	ENCODE Transcription Factor Targets	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.919323
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167125
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00205
Lung adenocarcinoma_LUAD_TCGA-53-7626-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE186810,GSE186813_2_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8326
HSD17B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68897
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3668
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EG-06A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.89
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039113
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03018
abnormal circulating lipid level	MPO Gene-Phenotype Associations	1.0	null
NCI-H64	GDSC Cell Line Gene Expression Profiles	-1.0	-1.70723
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055398
GSE235390_4_v_2_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3162
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
J-RT3-T3-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82913
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17901
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68705
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054359
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35331
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96184
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinoschisis	DisGeNET Gene-Disease Associations	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.49091
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4659
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.407
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26898
KMRC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45158
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1106
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ciliary transition zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.233
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE228125_2_v_1_ptafr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4469
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7495
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8418
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02026
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02308
TMEM98	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24459
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0158
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55558
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.00312
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70918
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59919
CAMK4	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4134
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09419
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28476
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3083
H3K36me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_6_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
dynamindependent	GeneRIF Biological Term Annotations	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	1.0	0.966516
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5055
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68509
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27761
BEN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47425
abnormal fat cell morphology	MPO Gene-Phenotype Associations	1.0	null
trans-golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.918579
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.1405
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.00312
abnormal body water content	MGI Mouse Phenotype Associations 2023	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.21
LAN2	DepMap CRISPR Gene Dependency	1.0	5.37323
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.99501
Bleb	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.578
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.723
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
beta1	Phosphosite Textmining Biological Term Annotations	1.0	null
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.676
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866137
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981687
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6688
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26963
Prostate adenocarcinoma_PRAD_TCGA-EJ-5527-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
duodenum	HPA Tissue Gene Expression Profiles	-1.0	-0.933004
GSE123836_2_v_3_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5844
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9774
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86899
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03748
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1473
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9944
BRCA1_02_202	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.5943
export	Phosphosite Textmining Biological Term Annotations	1.0	null
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21958
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04138
regulation of glucose transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5762-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27192
TCP1_02_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.78572
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.986
Neuron to neuron synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34141
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5906-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55677
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18411
Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174383_2_v_7_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34407
cSARS Bat SRBD_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.53936
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9666
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19741
transgolgi	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3372-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.824244
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4129
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5443
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6745
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081392
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15149
H3K36me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of protein localization to plasma membrane	GO Biological Process Annotations 2023	1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55695
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53117
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.905361
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4739-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.76
sglt1	GeneRIF Biological Term Annotations	1.0	null
GSE133213_9_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27237
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96589
GSE239747_2_v_3_lrp6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of nucleoside transport	GO Biological Process Annotations 2023	1.0	null
HSC39	DepMap CRISPR Gene Dependency	1.0	2.07945
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09815
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858608
SNU475	DepMap CRISPR Gene Dependency	1.0	2.02573
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.79271
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.779
Ubiquitin-associated/translation elongation factor EF1B, N-terminal, eukaryote	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5876-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6767
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24699
regulation of transport	GO Biological Process Annotations 2015	1.0	null
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58932
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51042
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20732
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35394
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75272
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3119
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3769
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958603
17699775-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SARS-dORF6_24Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40746
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.875
BL70	DepMap CRISPR Gene Dependency	1.0	2.69943
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882894
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1562
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85978
increased percent body fat	MPO Gene-Phenotype Associations	1.0	null
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.5262
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.7186
MFM-223	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A4S6-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAGEA9	MSigDB Cancer Gene Co-expression Modules	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7778
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3034
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0661
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52164
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0595
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.817
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.655
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.357
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5110-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of transmembrane transport	GO Biological Process Annotations 2023	1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4944
Sarcoma_SARC_TCGA-MO-A47P-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979451
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848322
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59454
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17145
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1701
cingulate gyrus, retrosplenial part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901185
Retinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94704
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063721
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.51825
cell junction	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TARDBP_02_116	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58761
GSE207471_2_v_1_btla_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899828
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167125
xenopus	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136627_7_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05228
Pancreatic adenocarcinoma_PAAD_TCGA-F2-7273-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5578
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.23274
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34098
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.189772
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.03766
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.084
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0995
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IK-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE255680_1_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_3_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Juvenile retinoschisis	ClinVar Gene-Phenotype Associations 2025	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32053
PMC11376028-13578_2024_1300_MOESM1_ESM.xlsx-CCF_2nd_round-SYMBOL_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91712
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.7995
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.236
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44344
skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6034
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36886
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51902
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.0754
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.945
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66368
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	76.2225
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5118
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.067
H3K36me3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34359
Cone telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.312
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3049
MDA-MB-468	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42678
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28845
RMG-I	GDSC Cell Line Gene Expression Profiles	1.0	2.17951
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5029704-oncotarget-07-24326-s006.xlsx-Sheet1-Genes_that_are_downregulated_in_low_TET1_compared_to_high_TET1_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12512
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.916214
20460173-ImmPortAnti-IgMvsControl	GeneSigDB Published Gene Signatures	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
CHD2_02_196	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.42066
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0912
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1102
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63134
OCIMY5	DepMap CRISPR Gene Dependency	1.0	2.19631
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250301
EOL-1-CELL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32137
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869541
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9924
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83659
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SF-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8487
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.755
regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64504
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.098
GSE133213_9_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
portal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404797
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3229
Lung adenocarcinoma_LUAD_TCGA-55-1592-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.990308
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.8325
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57415
FOSL1	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6542-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19349
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31709
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7754-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14608
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10636
Lung squamous cell carcinoma_LUSC_TCGA-63-5131-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338177
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47929
NF2	MSigDB Cancer Gene Co-expression Modules	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4882
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
shortterm	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867458
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37068
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7083
PRKCA	KEA Substrates of Kinases	1.0	null
KLE	DepMap CRISPR Gene Dependency	1.0	2.26894
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8952
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157F_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
C3A	CCLE Cell Line Gene CNV Profiles	1.0	1.7689
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042014
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6415
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877572
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1877
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4473
661W cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
Lung adenocarcinoma_LUAD_TCGA-50-5066-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36087
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.226331
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.72736
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4435
MZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.976405
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Organic cation/anion/zwitterion transport	Reactome Pathways 2024	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brush border	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9667
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14776
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70826
Vitreous humor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.967
GSE98964_0_v_2_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73797
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.5553
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5018
skin	HPA Tissue Gene Expression Profiles	-1.0	-1.38224
rs1	GeneRIF Biological Term Annotations	1.0	null
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
4star	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07311
Lung squamous cell carcinoma_LUSC_TCGA-52-7810-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Floret	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54117
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965559
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.311
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
CHP-212	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98361
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47925
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32018
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9493
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0269
NCI-H82	GDSC Cell Line Gene Expression Profiles	1.0	1.70555
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947194
Lung squamous cell carcinoma_LUSC_TCGA-98-A53A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal glucose absorption	MPO Gene-Phenotype Associations	1.0	null
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.835
regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
LMNA_02_175	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.24476
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5239
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20637
SKMM2	DepMap CRISPR Gene Dependency	1.0	3.14135
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.6
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06247
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2659
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2909
WM1799	DepMap CRISPR Gene Dependency	1.0	2.39388
SRSF9_02_134	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64756
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2495
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BY-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13772
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Pancreatitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
H3K36me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.98363
liver_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.17431
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.48061
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.962
Prostate adenocarcinoma_PRAD_TCGA-EJ-5508-01A-02R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RE-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152032_3_v_2_s1pr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33955
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.04201
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6241
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10033
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054635
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5206
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.891692
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1348
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genital pore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8607
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2236
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09641
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.38224
Dentatorubral-Pallidoluysian Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.887332
H3K36me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052455
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3921
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1811
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5302
ion channel inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.94365
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.255
nucleoplasm	GO Cellular Component Annotations 2015	1.0	null
Rhabdomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32434
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00135
lateral part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01077
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12698
sodium channel inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.3691
H3K36me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH209	CCLE Cell Line Gene CNV Profiles	-1.0	-2.27017
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.7316
Developmental and epileptic encephalopathy	ClinVar Gene-Phenotype Associations 2025	1.0	null
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GSE248858_6_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
GSE223334_1_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.421
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53585
FGFR1_activemutant_58_GSE17916	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.62487
increased body size	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11169
NCIH1385	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1796
CDX2-21074721-CACO-2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
nucleus	Phosphosite Textmining Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4861-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
LNZ308	DepMap CRISPR Gene Dependency	1.0	2.73479
RMGI	DepMap CRISPR Gene Dependency	1.0	3.21174
GSE145682_1_v_0_nbdy_human	RummaGEO Gene Perturbation Signatures	-1.0	null
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70954
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1203
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.579
negative regulation of protein localization to cell periphery	GO Biological Process Annotations 2025	1.0	null
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1523
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5797
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07617
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5474
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07162
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.40092
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	1.70723
negative regulation of nucleobase-containing compound transport	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38346
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4424-01A-22R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2949
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.844676
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20097
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
visual system development	GO Biological Process Annotations 2025	1.0	null
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.28333
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5288
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7899
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8518
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70386
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837798
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27107
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6538
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
channel inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11962
H1_BMP4_Derived_Mesendoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.37742
GSE168798_0_v_1_isg15_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933423
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.73075
Adrenocortical carcinoma_ACC_TCGA-OR-A5LL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1104
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18317
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053571
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5C0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_02_204	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59368
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39284
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26097
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NAA38	Pathway Commons Protein-Protein Interactions	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12759
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71603
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6203
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2939
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
18199535-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5359-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242199_2_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201042_2_v_1_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2721-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49091
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	2.17291
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.21
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3664
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06074
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2295
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
u251mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.900513
A2780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62273
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5245
GSE146074_1_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96184
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912481
glucose	Phosphosite Textmining Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-C_ATF4-def_vs_HCT116_DMSO8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.8915
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04448
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1086
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
codes	GeneRIF Biological Term Annotations	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0195
digestive/alimentary phenotype	MPO Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01408
sodium	Phosphosite Textmining Biological Term Annotations	1.0	null
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64943
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03574
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3965
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CJ-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal body fat mass	MPO Gene-Phenotype Associations	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26938
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7122
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.64
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1213
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13207
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3039
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051256
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10617
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.62565
Hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4227
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6086
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67051
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72669
Transport of bile salts and organic acids, metal ions and amine compounds	Reactome Pathways 2024	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31038
EW22	DepMap CRISPR Gene Dependency	1.0	3.71435
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1576
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01294
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07435
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91532
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25213
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.75271
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transporter	GeneRIF Biological Term Annotations	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.966246
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040778
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07447
k562	HPA Cell Line Gene Expression Profiles	1.0	2.38211
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.617
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17499
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Advanced Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7311
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MFE280	DepMap CRISPR Gene Dependency	1.0	2.01702
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34205
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
U031	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC-44	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138938_1_v_2_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1325
KLE	CCLE Cell Line Gene CNV Profiles	1.0	1.41626
regulation of protein localization to plasma membrane	GO Biological Process Annotations 2025	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.686
vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.32777
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_4_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
spectrin-associated cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07828
MDA-MB-231	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48839
Pancreas disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
intracellular	GeneRIF Biological Term Annotations	1.0	null
Central lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72254
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31277
COV318	CCLE Cell Line Gene CNV Profiles	1.0	1.40039
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.1
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00007
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10442
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42932
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67965
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32641
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9994
inhibits	GeneRIF Biological Term Annotations	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.5754
cotransporter	GeneRIF Biological Term Annotations	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849084
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67995
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6603
PMC5640240-ppat.1006668.s013.xlsx-MAX_ChIP_shEP400-1-Unnamed_6_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.928838
Protozoan Infection_Intestinal Epithelium_GSE2077	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49285
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48336
Pigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.566
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.87205
JHH2	DepMap CRISPR Gene Dependency	1.0	3.51291
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02114
llc-pk1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683919
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09716
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30004
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15827
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.539
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1354
DIFI	DepMap CRISPR Gene Dependency	1.0	7.43378
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.5126
LNCAPCLONEFGC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33496
GSE146074_1_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088473
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5504
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.8546
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43149
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39807
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.85814
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
History of neurodevelopmental disorder	ClinVar Gene-Phenotype Associations 2025	1.0	null
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04657
GSE147056_3_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0541
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.827886
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.841
NCI-N87	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56154
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927966
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10568
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.2711
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48102
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2959
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1841
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.749
PRKCA	Hub Proteins Protein-Protein Interactions	1.0	null
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06725
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0313
SW1463	DepMap CRISPR Gene Dependency	1.0	5.21014
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormal intestinal absorption	MPO Gene-Phenotype Associations	1.0	null
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.968
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29513
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01636
Lobule II	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74114
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23986
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932254
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19985
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51412
Retinoschisis	ClinVar Gene-Phenotype Associations 2025	1.0	null
nuclear part	GO Cellular Component Annotations 2015	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34894
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.99012
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adipose tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.063
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0101
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.949667
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5453
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12583
nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
abnormal cholesterol level	MPO Gene-Phenotype Associations	1.0	null
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64676
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09139
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.01419
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.3726
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35175
H3K36me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.92197
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36101
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4883
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27102
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8167
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2355
inhibition	GeneRIF Biological Term Annotations	1.0	null
abnormal adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.92711
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RL-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	3.14075
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12472
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09647
THRA	MSigDB Cancer Gene Co-expression Modules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2719-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.74175
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2029
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.28
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71007
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64339
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19415
werirb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.436
Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923301
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73793
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21375
channel regulator activity	GO Molecular Function Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59547
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.21
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3147
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0708
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10106
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4991-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2073
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34294
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7596-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201042_6_v_7_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4332
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8473
PMC4051124-1471-2164-15-256-S11.XLSX-WES_MSMD-STAT1-Target_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3922
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.148
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2132
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4374
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270909
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.48818
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1944
Retinoblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cell junction	GO Cellular Component Annotations 2015	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0808
negative regulation of protein localization to membrane	GO Biological Process Annotations 2023	1.0	null
Sporangiophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8876
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82067
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18865
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35064
MEWO	CCLE Cell Line Gene CNV Profiles	1.0	1.35961
H3K36me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52092
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.757
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
increased circulating leptin level	MPO Gene-Phenotype Associations	1.0	null
visual perception	GO Biological Process Annotations 2025	1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.873
hippocampus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50454
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.507
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973214
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07214
Lung adenocarcinoma_LUAD_TCGA-86-8056-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9884
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4891
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3811
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8347
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053933
GSE234155_7_v_1_nfix_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01285
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE87412,GSE92423_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.97155
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47409
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03474
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08307
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.78359
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967742
abnormal digestion	MPO Gene-Phenotype Associations	1.0	null
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19025
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450271
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11498
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleobase-containing compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02724
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.6962
Flagellum attachment zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7524
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19077
NCIH28	DepMap CRISPR Gene Dependency	1.0	3.83632
rsc1a1	GeneRIF Biological Term Annotations	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838417
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46821
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967742
GSE160817_2_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
HCC1428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.844
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3371
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.20151
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32137
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.877572
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15832
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96184
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2523
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
network	GeneRIF Biological Term Annotations	1.0	null
increased fat cell size	MPO Gene-Phenotype Associations	1.0	null
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76468
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0939
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1043
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.927175
KIAA0930	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83791
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCoV-EMC2012_3Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.47823
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39603
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7844
GSE165647_0_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898225
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.853812
chromosome, subtelomeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31693
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.08664
NB10	DepMap CRISPR Gene Dependency	1.0	2.20329
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4919
Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85516
Sweet taste receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.712
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	107.569
Edema	CTD Gene-Disease Associations	1.0	1.09011
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89039
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13775
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186810,GSE186813_2_v_1_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
trafficking	GeneRIF Biological Term Annotations	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95
negative regulation of nucleobase-containing compound transport	GO Biological Process Annotations 2023	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
GSE133213_2_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188352
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.3778
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0551
OE21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9443
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5048
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65553
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17082
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70814
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33185
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406694
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35878
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2583
PMC12179083-Table_6.xlsx-VCF_Variants_Master_File-Gene_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154940_1_v_0_nbdy_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.00888
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.950355
sensory perception of light stimulus	GO Biological Process Annotations 2025	1.0	null
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65381
GSK3B_KD_GDS4305_185_human_U937 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8047323-Table_3.xlsx-Venn_581_LPS_T24_vs_LPS_T0-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.18248
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5439
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057774
T-tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.775
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8332
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.9
sf-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.207147
H3K36me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.854618
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.926222
containing	GeneRIF Biological Term Annotations	1.0	null
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34952
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.523
sodium channel regulator activity	GO Molecular Function Annotations 2025	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
active-transport-cell-nucleus	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978903
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.51335
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19028
ChIP_TCF3_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39482
ion channel inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17019
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36413
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832066
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATAD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65653
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39039
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H226Br cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
GSE248858_1_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130396_0_v_2_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.88745
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5351
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.00312
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838417
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.169
Brain edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02025
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49345
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.866
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17145
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99325
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.612
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69603
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991985
CHD1_02_187	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61965
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.03938
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23195
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
JAR	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041318
pparg_21068720_macrophage_c57bl6_lof_mouse_gpl1261_gds4370	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.373325
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04814
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28869
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.950736
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09555
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.979924
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02818
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.544
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60552
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.48118
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21824
DSH1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXR-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.992509
PLK1_knockdown_98_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.80479
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06682
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9522
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6109
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90483
GSE77795_0_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatorenal Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.849
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Vitreous chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
Rectum adenocarcinoma_READ_TCGA-EI-6882-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.506
Low Vision	DisGeNET Gene-Disease Associations	1.0	null
Interphotoreceptor matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.846
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.5168
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.14616
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060131
eye development	GO Biological Process Annotations 2025	1.0	null
H3K36me3_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4959-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A23T-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87197
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991961
import	Phosphosite Textmining Biological Term Annotations	1.0	null
OE33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ECC12	GDSC Cell Line Gene Expression Profiles	1.0	1.63867
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83324
nuclei	Phosphosite Textmining Biological Term Annotations	1.0	null
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05325
fat_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.925267
rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE174383_4_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39059
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9429
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976966
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25U-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.5878
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.85512
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3581
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7101
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.944222
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.18442
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19914
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1865
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73785
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A97N-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.959
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32177
LN319	CCLE Cell Line Gene CNV Profiles	1.0	1.84742
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37839
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.924883
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874555
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.89
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21289
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43965
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.44618
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0501
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0541
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149010_0_v_4_dars2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
taken	GeneRIF Biological Term Annotations	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27929
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell junction	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.387
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908678
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866137
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.296
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69907
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5363
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1975
CORL88	CCLE Cell Line Gene CNV Profiles	1.0	3.23418
Chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.882
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47184
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835451
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.29
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.734
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.6048
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46961
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3275
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Supplementary_Table_2D_Contrast_ATF4-def_Tg_2h_vs_HCT116Tg_2h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.33396
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22764
DYNLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49745
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8604
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5542-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11386
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	2.72005
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063178
TCF3-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6884
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.962051
CDK4_knockdown_85_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.54421
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1729
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20637
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967742
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22211
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04689
negative regulation of transport	GO Biological Process Annotations 2023	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.10432
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.871773
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Middle Cerebral Artery Occlusion	DisGeNET Gene-Disease Associations	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4525
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1266
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.43761
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341126
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
IMR-32 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02933
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.634
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67045
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3295
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15477
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967742
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE197564,GSE198512_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21824
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31782
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2454
negative regulation of protein transport	GO Biological Process Annotations 2025	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.522
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6011-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201042_6_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243918
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876445
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9173
Intestinal absorption	Reactome Pathways 2024	1.0	null
PMC7468443-Data_Sheet_2.xlsx-DEG_2h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81992
15171711-Table1	GeneSigDB Published Gene Signatures	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05218
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7064
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BFTC909	DepMap CRISPR Gene Dependency	1.0	2.08038
increased cholesterol level	MPO Gene-Phenotype Associations	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0576
Conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4671
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4425
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-D_ATF4-def_vs_HCT116_Tg2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03786
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3942
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.204452
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9906
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19473
pkcdependent	GeneRIF Biological Term Annotations	1.0	null
MDM2	MSigDB Cancer Gene Co-expression Modules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7422-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.96027
obese	MPO Gene-Phenotype Associations	1.0	null
LMNB2_02_191	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.57994
ZR7530	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38402
Y-79 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
NAMALWA	CCLE Cell Line Gene CNV Profiles	1.0	1.39013
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amoeboid microglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
STAT5A_02_182	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.83519
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43632
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02993
Hyalocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.603
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5954
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03084
negative regulation of nucleoside transport	GO Biological Process Annotations 2025	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.238
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201217_3_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RSV-A2_24Hour-B6.129PF1_J_None_GSE18170	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.02123
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27752
CRCGN009_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17418
CVB3_9Hour-Infection+U0126_None_GSE697	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.67896
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C84	DepMap CRISPR Gene Dependency	1.0	5.37599
External side of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	1.35253
GSE201217_2_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40639
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.57
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6371
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23354
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2768
skin_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.49896
GSE248634_1_v_0_gnas_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09947
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26297
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3378-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A7EF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5709
LOUCY	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89327
modulates	GeneRIF Biological Term Annotations	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.409
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22911
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal circulating cholesterol level	MPO Gene-Phenotype Associations	1.0	null
PRKCA	PhosphoSitePlus Substrates of Kinases	1.0	null
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94864
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
vesicles	GeneRIF Biological Term Annotations	1.0	null
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
lymphnode_5a	HPA Tissue Sample Gene Expression Profiles	1.0	2.05153
Necrosis	CTD Gene-Disease Associations	1.0	1.1437
NUMA1	MSigDB Cancer Gene Co-expression Modules	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27475
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4_02_200	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.75489
Cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.779
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17037
Lung adenocarcinoma_LUAD_TCGA-91-6831-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68296
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054455
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77404
increased sterol level	MPO Gene-Phenotype Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92443
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05097
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054235
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8201
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32097
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1729
PMC9999213-mmc3.xlsx-DEGs_CSc-DEA_NB_MSC_EC_CSc_vs_NB_CSc_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EA-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.843206
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
MND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63819
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5004
NMC-G1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.05456
SRY	JASPAR Predicted Transcription Factor Targets	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0548
Mhs	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5982
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827406
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85257
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057025
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7841
PMC11525188-41588_2024_1893_MOESM4_ESM.xlsx-Supplementary_Table_4-Supplementary_Table_4_NSD2_signature_genes_and_GREAT_genes_associated_with_NSD2-dependent_and_NSD2-independent_AR_binding_sites_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11235
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0296
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1228
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37709
GSE151782_2_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08307
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3755
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855281
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26462
GSE149854_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5018
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9264
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.2489
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25213
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7029
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.75658
NMRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62739
NCI-H510A	GDSC Cell Line Gene Expression Profiles	1.0	2.08078
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08979
PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.980685
abnormal circulating hormone level	MPO Gene-Phenotype Associations	1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23881
spi1_17041602_preleukemic_hscs_lof_mouse_gpl1261_gds2411	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.19352
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01821
CLASRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93361
Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Sarcoma_SARC_TCGA-DX-A6B8-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060637
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.0117
negative regulation of protein transport	GO Biological Process Annotations 2023	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06037
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22639
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6687
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.785
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994731
RBPJ-21746931-IB4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
u698	HPA Cell Line Gene Expression Profiles	1.0	1.31751
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17835
PMC11373733-ABR-13-34_Suppl1.pdf-358-KLF9-DT_KLF9	Rummagene Transcription Factor Associations 2026	1.0	null
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8262
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32481
KPNYN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64522
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K36me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rett Syndrome_frontal cortex_GSE6955	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.91584
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6112
RMGI	CCLE Cell Line Gene CNV Profiles	1.0	2.42367
regulation of D-glucose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11223
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01147
Body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.64
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9634663-DataSheet10.xlsx-K562-MYC-AID_RNA-Seq_1326_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Failure, Acute	DisGeNET Gene-Disease Associations	1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.08231
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2446
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68294
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4797-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56657
biological_process	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01844
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediates	GeneRIF Biological Term Annotations	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3028
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.562
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2175
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.49277
GSE190384,GSE190386_0_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell-nucleus	Phosphosite Textmining Biological Term Annotations	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.983
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29288
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12074
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDKL5 disorder	ClinVar Gene-Phenotype Associations 2025	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053119
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882219
Postsynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909098
17234769-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
Blastocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN015_MCF10A_48H:F02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48997
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of transport	GO Biological Process Annotations 2025	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.947727
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057267
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55563
PEO4	DepMap CRISPR Gene Dependency	1.0	2.42015
nadglucose	GeneRIF Biological Term Annotations	1.0	null
ETV1-20927104-GIST48-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20006
PRKCA	Pathway Commons Protein-Protein Interactions	1.0	null
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1397
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.306
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.00312
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33706
cellular nitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Organic cation transport	Reactome Pathways 2024	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8801
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.6762
C3A	GDSC Cell Line Gene Expression Profiles	1.0	2.05983
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1525
MYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6706
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.830505
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.51252
SCC9	DepMap CRISPR Gene Dependency	1.0	6.13758
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069203
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08625
Lung adenocarcinoma_LUAD_TCGA-86-8075-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6176
named	GeneRIF Biological Term Annotations	1.0	null
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
protein-transport	Phosphosite Textmining Biological Term Annotations	1.0	null
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
sodium channel inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
OAW42	DepMap CRISPR Gene Dependency	1.0	2.53115
regulation of Golgi to plasma membrane protein transport	GO Biological Process Annotations 2025	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960213
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.22639
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0301
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051465
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of transport	GO Biological Process Annotations 2023	1.0	null
cell periphery	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10216
COR-L88	GDSC Cell Line Gene Expression Profiles	1.0	2.16774
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20288
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.7341
exhibits	GeneRIF Biological Term Annotations	1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42712
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89991
PAX7	MSigDB Cancer Gene Co-expression Modules	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11049
negative regulation of D-glucose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58765
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.30459
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12245
BHT101	DepMap CRISPR Gene Dependency	1.0	2.26671
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5843
abnormal adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
IEC-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
aging	GAD High Level Gene-Disease Associations	1.0	0.293278
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC8047323-Table_1.xlsx-FC_LPS_T24_Vs_LPS_T0_P_0_05_FC-GeneSymbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149870_0_v_1_pfn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6697
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Lung adenocarcinoma_LUAD_TCGA-86-7713-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNURF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89246
Sarcoma_SARC_TCGA-N1-A6IA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75378
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.144
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TTC642	DepMap CRISPR Gene Dependency	1.0	2.52945
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.967
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29288
PMC4729482-pone.0146505.s001.xlsx-Sheet1-ccRCC_positively_correlated_with_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133213_9_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08467
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MI-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
beta-mannosidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.983
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08253
Systemic Inflammatory Response Syndrome	DisGeNET Gene-Disease Associations	1.0	null
cell-cycle-proteins	Phosphosite Textmining Biological Term Annotations	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.2244
Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
17683608-TableS5	GeneSigDB Published Gene Signatures	1.0	null
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85766
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75447
ion channel inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05121
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5165-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928571
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988332
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62539
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.342
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47182
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.9777
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40031
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.940308
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4287
golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.8263
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.36943
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45103
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7883
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.377
localization	GO Biological Process Annotations 2015	1.0	null
MAP2K7	MSigDB Cancer Gene Co-expression Modules	1.0	null
ZMIZ1_02_181	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61808
GSE133683_1_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6875
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26596
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59823
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22211
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TT-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EVI1-22308434-SKOV3-HUMAN-OVARY-OVARIANCANCER	ChEA Transcription Factor Targets 2022	1.0	null
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092847
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27596
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.842
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.578
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50579
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3932
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059007
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21289
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.87703
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Golgi apparatus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.387
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6795
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34616
Prostate adenocarcinoma_PRAD_TCGA-J4-8198-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE130396_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.038993
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.58599
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40701
negative regulation of protein localization to plasma membrane	GO Biological Process Annotations 2023	1.0	null
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19498
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08467
Sarcoma_SARC_TCGA-X6-A8C2-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
inner SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842536
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.849
Rod photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.758
PMC7611259-EMS114661-supplement-Supplementary_Tables.xlsx-ST18-Unnamed_10_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.795
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.451
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5764-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dinoflagellate epicone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.832345
CTV-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14081
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.42711
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95574
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
TBL1XR1_02_178	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65148
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83955
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.02818
GSE224131_2_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06892
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841031
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	71.2685
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09819
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-11A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZD-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06861
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38397
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null