association	dataset	threshold value	standardized value
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87847
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18937
STAT1	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.921348
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.476
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048615
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5048
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18324
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898895
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0325
UBE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41699
thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.680248
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80918
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35081
ZNF143	ENCODE Transcription Factor Targets	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91658
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77909
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.941
spermatid development	GO Biological Process Annotations 2023	1.0	null
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
axoneme assembly	GO Biological Process Annotations 2025	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5159-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.247789
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98922
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71504
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.937301
CEP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61051
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903805
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3574
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16225
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303919
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC3507642-1471-2164-13-355-S4.xlsx-direct_AR-repression_Cmpd30-UP-HUGO_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.44899
S0-EE-Y97N_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262327
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204263
primary ciliary dyskinesia	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Trypanosomoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7888
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20988
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953246
GATA2	ChEA Transcription Factor Targets	1.0	null
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35925
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CCDC112	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30268
AE-85-KE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.226472
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36153
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40575
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.933
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2641
Peg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6865
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.04795
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.826
Asthma	DisGeNET Gene-Disease Associations	1.0	null
KARPAS-620	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.801758
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE115283_1_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24966
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917192
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03494
cell projection assembly	GO Biological Process Annotations 2015	1.0	null
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
etiology	GeneRIF Biological Term Annotations	1.0	null
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29579
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830678
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03718
Axonemal basal plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.548
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39875
Primary ciliary dyskinesia	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825965
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.015496
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.884179
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.33541
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.15723
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33069
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MORN motif	InterPro Predicted Protein Domain Annotations	1.0	null
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.132157
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91862
ARL6IP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37262
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02556
GTEX-XBED-2326-SM-47JYR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Hemorrhage	CTD Gene-Disease Associations	1.0	1.15156
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06628
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88045
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835321
FIGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36137
ELF1	ENCODE Transcription Factor Targets	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.286
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080308
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26171
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885429
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65418
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Orr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
CDPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67608
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
16141321-Table2	GeneSigDB Published Gene Signatures	1.0	null
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52227
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35258
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.877
bj	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_Jurkat_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ABCA1_OE_GDS2303_189_mouse_LDL receptor-deficient livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NFYA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
Respiratory bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
intracellular part	GO Cellular Component Annotations 2015	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54354
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55829
decreased germ cell number	MPO Gene-Phenotype Associations	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880038
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40323
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51651
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
NAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03538
Lung squamous cell carcinoma_LUSC_TCGA-22-5479-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20566
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827606
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
spleen_3d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.319
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.957804
microtubule bundle formation	GO Biological Process Annotations 2023	1.0	null
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18441
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.912
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82205
Distal tip cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15244
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988206
Ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2318
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74467
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63464
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10526
myocardial infarction	GWASdb SNP-Phenotype Associations	1.0	0.508017
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826868
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20207
valproic acid_mus musculus_gpl6885_gse41020	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GRTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93477
CFTR_Deficiency_GDS1843_191_mouse_Lungs - Animals examined at 3 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03086
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1863
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
meiotic cell cycle	GO Biological Process Annotations 2015	1.0	null
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Gastrula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92539
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cranioectodermal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	0.969594
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.487915
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.14885
KDM1A	ENCODE Transcription Factor Targets	1.0	null
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
GSE199660_1_v_2_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8633
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08354
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34028
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8061
flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.949101
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	7.66745
PANC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0241
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3559
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16099
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
ERGIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75805
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20178
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.476
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YPEL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05356
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9805
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Ectopic Pregnancy	DisGeNET Gene-Phenotype Associations	1.0	null
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37413
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22482
GTEX-QCQG-1926-SM-2S1PI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03557
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF3	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74984
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.514085
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976173
ATP5ME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77994
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984122
E2F2_KD_GDS4094_447_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.59427
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826056
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18746
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ELF5	ChEA Transcription Factor Targets	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33586
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE220520_6_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996923
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.528
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8383
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900695
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900753
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51472
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90202
evidence	GeneRIF Biological Term Annotations	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51078
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853859
Prothallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45391
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927475
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223334_1_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2784
ID4_KO_GDS4178_620_mouse_Splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886339
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070024
Biliary tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.512
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.846411
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9891
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0602
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11493
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77579
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23461
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1137
Ciliated cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
Idiopathic Bronchiectasis	DisGeNET Gene-Disease Associations	1.0	null
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45761
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46597
decreased body size	MPO Gene-Phenotype Associations	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.898492
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IMPDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45435
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07114
cilium	GO Cellular Component Annotations 2025	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	0.966891
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sporophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24902
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.083528
GSE137144_4_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77142
primary	GeneRIF Biological Term Annotations	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_10_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49529
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12175
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07029
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23538
SZT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13212
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49604
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12159
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
at1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
TNKS1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67954
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCA1_Knock-in_GDS3544_561_mouse_Cerebellum - 4 Weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51281
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Radial spoke stalk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.854
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20655
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922768
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05058
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59957
thymus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.146783
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_4_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39751
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Otorrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41383
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89537
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95318
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51044
Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51269
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91786
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39897
outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.653019
motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.875488
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43481
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.919068
CMK	CCLE Cell Line Gene CNV Profiles	1.0	1.72547
HCC366	DepMap CRISPR Gene Dependency	1.0	3.65091
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.031253
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854945
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS600T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56713
GTEX-UTHO-1026-SM-3GAF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960688
Megasporangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13807_KD_Qki_SRP116547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
chr21_42479044_A_G_b38	GTEx eQTL 2025	1.0	1.10753
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vasculature-b cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.168236
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12451
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15502
Lung	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.42186
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.919726
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.428234
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969734
an3ca	HPA Cell Line Gene Expression Profiles	1.0	0.844666
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07454
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
myocardial infarction	GAD Gene-Disease Associations	1.0	null
GTEX-SE5C-0426-SM-4BRUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827227
nucleus	GO Cellular Component Annotations 2023	1.0	null
cell cycle	GO Biological Process Annotations 2015	1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23557
GSE242521,GSE242522_0_v_1_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Male infertility due to acephalic spermatozoa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
MYC	ENCODE Transcription Factor Targets	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901236
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.89925
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Middle ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.213
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20539
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1306
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.82
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19603
RERFLCSQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54726
CUX1	ENCODE Transcription Factor Targets	1.0	null
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.308034
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41338
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Flagellate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.883
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891437
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20444
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44667
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894957
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938508
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.05128
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.887072
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8728
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.216109
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.953832
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21044
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07787
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35573
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989112
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30101
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.954872
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187591
Tracheobronchial epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.944592
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02371
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04647
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
ANKRD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30545
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.587054
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64525
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856631
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.145
MM1S	CCLE Cell Line Gene CNV Profiles	1.0	1.44842
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17111
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28463
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.934054
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR16	DepMap CRISPR Gene Dependency	1.0	2.24682
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70U-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839623
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22062
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
MAX	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63439
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27745
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.697
Primary ciliary dyskinesia 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.382881
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57187
RFX5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0545
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Classical_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5494
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15952
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.878273
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200763
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16626
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13394
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32132
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.689
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0277
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
AKT1_druginhibition_81_GSE26290	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.40817
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69014
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17111
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60277
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JE-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.909737
PECAPJ34CLONEC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91127
Edema	CTD Gene-Disease Associations	1.0	1.26021
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2031_KO_Chd4_SRP079694	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.648
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58285
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NC-01-ET52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.262028
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826956
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0482
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09159
ZNF570	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67606
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1994
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6868
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05497
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
Lung-lung ciliated cell	Tabula Sapiens Gene-Cell Associations	1.0	10.1593
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27741
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.94867
foxa1_21151129_mcfdash7_lof_human_gpl10558_gse25315	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.32959
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.101848
bronchiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.766759
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72709
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46531
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PPIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37165
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00683
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.6371
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879275
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17606
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65162
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP42-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	3.80953
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleotide-excision repair factor 4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.719
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08487
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47384
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865753
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.268
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22316
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU520	CCLE Cell Line Gene Expression Profiles	1.0	3.15914
EDEM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36973
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067652
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
recurrent respiratory infections	HPO Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952965
NAGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99686
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.669153
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.839504
BCKDK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13869
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47966
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.496
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.026354
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25444
Perturb_10356_KD_BRD4_SRP093774	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esr1_21713035_mcf7_lof_human_gpl570_gds4061	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.94622
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cytosol	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTPN1_KD_GSE54157_673_human_KM-H2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887183
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30234
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85697
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
suggesting	GeneRIF Biological Term Annotations	1.0	null
PrPC_KO_GDS4352_358_mouse_Developing hippocampus from FVB newborns (4.5-day-old)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.95291
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
ULK1_knockout_197_GSE60778	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.17531
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.196139
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87661
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
H2AC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43075
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05992
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36764
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.20702
THAP1	ENCODE Transcription Factor Targets	1.0	null
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918677
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833103
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07769
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.352
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11669
Ciliopathy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43615
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00594
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98872
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42973
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.08161
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57042
MRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29177
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ZNF263	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23645
abnormality of the upper respiratory tract	HPO Gene-Disease Associations	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970558
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.897503
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23467
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3276
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4174-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sperm individualization complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977222
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.877363
PMC6424977-41467_2019_9182_MOESM10_ESM.xlsx-MI-ID_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3147
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6831
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0749
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.770883
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828043
IB-67-WH43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.273146
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.976293
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14495
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.50212
Clubbed Fingers	DisGeNET Gene-Disease Associations	1.0	null
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57459
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.49917
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.17399
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85016
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
all	HPO Gene-Disease Associations	1.0	null
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73625
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9123
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902027
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
genotypephenotype	GeneRIF Biological Term Annotations	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893928
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mode of inheritance	HPO Gene-Disease Associations	1.0	null
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91666
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12700831-41594_2025_1680_MOESM4_ESM.xlsx-D9_EC_Hits_2_5FC_CRAPomeFilt-Mapped_Gene_Symbol_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889154
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967543
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4756
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.73735
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.373605
WT1	ChEA Transcription Factor Targets	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
relationship	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4772-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.77601
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.98726
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.88796
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26185
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Primary ciliary dyskinesia 24	ClinVar Gene-Phenotype Associations	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832237
SLTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10093
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11327
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21543
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
abnormality of cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.227025
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.38202
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.476
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.07732
SMARCC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
PMC11462941-CAS-115-2947-s001.pdf-104-HMBOX1_HMBOX1	Rummagene Transcription Factor Associations 2026	1.0	null
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
abnormal gametes	MPO Gene-Phenotype Associations	1.0	null
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96023
MICAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33534
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.952233
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48167
YEATS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36007
CREB1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8384902-mmc7.xlsx-105_ASCL1_Direct_repressed-Unnamed_7_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.382884
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.028
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95056
organelle	GO Cellular Component Annotations 2015	1.0	null
Perturb_15364_KO_Mef2c/Mef2d_SRP064307	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9475
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24962
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-2.4381
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
CORL311	CCLE Cell Line Gene Expression Profiles	1.0	1.52552
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TOP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22237
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09525
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
tr96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.312
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal spermatogenesis	MPO Gene-Phenotype Associations	1.0	null
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.61
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.16269
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51044
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76019
AMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81833
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77269
Yolk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
PDPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70734
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ankylosing Spondylitides_macrophage_GSE11886	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.44976
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15938
Asthenozoospermia	DisGeNET Gene-Disease Associations	1.0	null
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921115
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98925
LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1144
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25569
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67909
Perturb_5823_KO_Ebf1_SRP095167	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24267
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motile cilium	GO Cellular Component Annotations 2023	1.0	null
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829243
Kartagener syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986639
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.67912
CREB1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841549
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ectopic pregnancy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
ELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92723
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8246
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.348581
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
USF2	ENCODE Transcription Factor Targets	1.0	null
Type II protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56573
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.328
Respiratory system_CT1_airway submucosal gland ciliated duct cell	HuBMAP ASCT+B Annotations	1.0	null
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953546
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0344
IRF3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostasome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
Posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.323
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02452
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61675
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
organelle organization	GO Biological Process Annotations 2015	1.0	null
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26171
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8617
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular component assembly	GO Biological Process Annotations 2025	1.0	null
CME1	DepMap CRISPR Gene Dependency	1.0	13.6603
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.083
FAM110A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85716
Axoneme	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Corneal Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6565
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.36104
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3725
Perturb_4840_OE_Gfi1/Atoh1_SRP220284	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.50764
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8384902-mmc7.xlsx-105_ASCL1_Direct_repressed-Unnamed_15_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH2106	CCLE Cell Line Gene CNV Profiles	1.0	1.56719
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2818
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE127970_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25X-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.26329
Mucosa	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.028
Headfoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
Primary ciliary dyskinesia	ClinVar Gene-Phenotype Associations 2025	1.0	null
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SMIM30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71257
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5166
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904117
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.63116
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
STXBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58871
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_4709_KO_Hesx1_ERP023509	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.46129
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548u	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
LS	DepMap CRISPR Gene Dependency	1.0	2.23657
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17484
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CW2	CCLE Cell Line Gene Expression Profiles	1.0	1.43902
SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KANSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49971
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939737
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7899452-media-4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.00058
ZNF678	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12443
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87968
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARS CoV_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.87863
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36633
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47904
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09159
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87011
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24281
infertility	HPO Gene-Disease Associations	1.0	null
PMC8299217-mmc4.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.863048
Immotile Cilia	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal male germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22039
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SS18L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15712
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44787
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.172
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04007
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS618T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75438
residual	GeneRIF Biological Term Annotations	1.0	null
bronchiectasis	HPO Gene-Disease Associations	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cleft Lip	CTD Gene-Disease Associations	1.0	1.11741
DPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59607
20035825-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01721
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880019
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069901
hel	HPA Cell Line Gene Expression Profiles	1.0	0.955038
abnormality of ion homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.227025
Bile duct disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.512
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51683
Perturb_2821_KD_Src_SRP194728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.10126
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47339
cellular component assembly	GO Biological Process Annotations 2023	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Respiratory system_CT1_ciliated cell of the bronchu	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
localization	GeneRIF Biological Term Annotations	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8016
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56682
PAX5	ENCODE Transcription Factor Targets	1.0	null
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40686
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5516
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68341
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62892
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.4684
abnormality of the tracheobronchial system	HPO Gene-Disease Associations	1.0	null
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45094
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6806
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18903
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05015
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5472-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43362
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.07125
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4107
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
Sclerosing cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.512
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.596482
IA-76-ZU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.21625
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53572
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21985
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Celiac disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.366
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.465
YY1	ENCODE Transcription Factor Targets	1.0	null
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58698
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878187
Nasal Polyps	DisGeNET Gene-Disease Associations	1.0	null
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7842
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
R2TP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ciliary dyskinesia, primary, 24	OMIM Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76141
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03686
bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.134277
hsa-miR-1179	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17278
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21789
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17603561-STable1	GeneSigDB Published Gene Signatures	1.0	null
u251mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208893
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37417
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
hsa-miR-378f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51507
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.956302
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04251
FAM20C	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2769
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24816
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.04659
CHD1	ENCODE Transcription Factor Targets	1.0	null
HOXC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1613
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
KMH2	CCLE Cell Line Gene Expression Profiles	1.0	2.12212
PLXNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.674
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23758
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1588	CCLE Cell Line Gene Expression Profiles	1.0	2.40671
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Cerebral Ventriculomegaly	DisGeNET Gene-Phenotype Associations	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49303
RCOR3	ChEA Transcription Factor Targets	1.0	null
Respiratory system_CT1_airway submucosal gland ciliated duct cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.896487
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10566
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48042
E2F6	ENCODE Transcription Factor Targets	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.50618
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01523
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30304
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64863
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.09857
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06076
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918677
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21709
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.39669
KE-91-GT92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220734
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23987
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67909
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00603
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43291
NRF1	ENCODE Transcription Factor Targets	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.0751
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08668
HCC1419	CCLE Cell Line Gene Expression Profiles	1.0	1.43145
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35897
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
HGC-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
abnormal gametogenesis	MPO Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05807
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871998
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LS180	CCLE Cell Line Gene Expression Profiles	1.0	1.46321
axoneme assembly	GO Biological Process Annotations 2015	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.960269
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
provides	GeneRIF Biological Term Annotations	1.0	null
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dynein axonemal particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.467
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891464
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3735
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5445
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07465
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01689
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37448
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5372
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40635
FGFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11129
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893223
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63353
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46343
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03256
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCTD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12814
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.82699
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.700671
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.760742
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192259
abnormal sperm flagellum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
oligozoospermia	MPO Gene-Phenotype Associations	1.0	null
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82234
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.76785
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
17483317-TableS4	GeneSigDB Published Gene Signatures	1.0	null
SERINC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13221
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRECLH	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65645
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.594259
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WM115	DepMap CRISPR Gene Dependency	1.0	5.27537
SYCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94527
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061608
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69611
PMC12169532-pone.0325700.s010.xlsx-Table_S4-Table_S4_List_of_genes_that_upon_knockdown_KD_led_to_transcriptional_signitures_similar_to_the_input_DEG_set_of_CRC_or_LIHC_and_their_KEGG_enrichment_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal sperm head morphology	MGI Mouse Phenotype Associations 2023	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09159
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345942
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
preweaning lethality, incomplete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GAPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39396
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22131
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Chronic Sinusitis	DisGeNET Gene-Disease Associations	1.0	null
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16939
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04793
Respiratory system_CT1_lung ciliated cell	HuBMAP ASCT+B Annotations	1.0	null
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15828
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056581
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	2.21582
Airway fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1762
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU869	CCLE Cell Line Gene Expression Profiles	1.0	1.59214
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19305503-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SJ-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46315
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.91548
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210549
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.052
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832235
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
GATA3-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.919726
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.9332
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21523
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02747
Perturb_9409_Mut|KO_Kras_SRP272482	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.81984
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852545
pharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37087
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35075
PPP1R7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16213
ESRRB	ChEA Transcription Factor Targets	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57334
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
FIZZ2_KO_GDS4902_408_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32341
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.731442
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.083
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4746
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6716
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58367
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19190338-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
carpel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.741327
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30766
Secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94589
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888827
GSE203158_0_v_13_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Radial spoke head	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ZFP42	ChEA Transcription Factor Targets	1.0	null
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.40942
artery disease	GWASdb SNP-Disease Associations	1.0	0.100355
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043436
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84205
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11364
T24	DepMap CRISPR Gene Dependency	1.0	5.84838
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.46189
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17152
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53395
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1611
Spermatogenic failure 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910499
REC1	CCLE Cell Line Gene Expression Profiles	1.0	2.26948
Hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
appear	GeneRIF Biological Term Annotations	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44671
CALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51855
MME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75507
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46643
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67289
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.087
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BTK_knockout_2_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.094059
CREB1-15753290-HEK293T-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	2.80387
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CSNK2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12549
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4177-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Recurrent Respiratory Infections	DisGeNET Gene-Phenotype Associations	1.0	null
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02196
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0362
GSE173810_4_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826304
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59174
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.08687
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854945
ARL5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04181
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.117816
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43396
H3K9ac_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02277
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858248
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine endometrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.028
abnormality of the lung	HPO Gene-Disease Associations	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.512
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.446
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16364
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43863
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96097
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.343
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9396374-Table_4.XLSX-AR_related_genes_from_OMIM-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4634	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37524
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924734
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	1.15479
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24808
Nephronophthisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19509
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64965
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CGR-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61907
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95041
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052023
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08504
male infertility	MPO Gene-Phenotype Associations	1.0	null
GSE118794_0_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMTM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67707
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843423
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.975568
Chronic rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
ESCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61561
ELK1	ENCODE Transcription Factor Targets	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	1.41374
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ellis-Van Creveld syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XV7Q-0826-SM-4BRV7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-417-PRDM15_PRDM15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03408
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small_Intestine	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.12791
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF420	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4021
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Type I terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
MEF2A_01_265	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.8406
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4105
DA-27-BW20_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216326
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09184
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63692
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40094
Ciliopathies	WikiPathways Pathways 2024	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34528
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25391
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17192395-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971381
HEL9217	DepMap CRISPR Gene Dependency	1.0	4.59563
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Magnesium	dbGAP Gene-Trait Associations	1.0	0.471797
TP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37498
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46582
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.169
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15155
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854055
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25092
CL34	CCLE Cell Line Gene Expression Profiles	1.0	1.65022
NCIH196	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23672
TCF12	ENCODE Transcription Factor Targets	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21627
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852964
Central cylinder	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
20208059-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.912892
APOD_OE_GDS3913_489_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03144
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68596
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879192
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00014
GSE210476_11_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31524
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.23108
oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ABCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61281
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nsk1-Dlc1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.83976
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66024
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66721
GNG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03775
Spontaneous Abortion	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_4522_KO_Mapk3_SRP281895	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33823
thioredoxin-disulfide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.649
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17093
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17802
Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99982
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05072
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208348
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35998
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
lung	HPA Tissue Gene Expression Profiles	1.0	0.97284
Perturb_1240_KD_SRSF3_SRP033393	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.38651
km3	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87731
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
PBX3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6975
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13396
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01395
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00907
DUX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18037
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14361
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.429547
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MHHCALL2	CCLE Cell Line Gene CNV Profiles	1.0	1.6411
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RPL35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55306
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925678
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6658
Trachea_CT1_ciliated cell of terminal ciliated ducts of submucosal gland	HuBMAP ASCT+B Annotations	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.843014
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054851
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11464
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831816
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13918
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844126
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.51305
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.288
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Scoliosis, Unspecified	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3669
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.612
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A3-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396087
CCT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49091
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.66
hsa-miR-941	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
anatomical structure formation involved in morphogenesis	GO Biological Process Annotations 2015	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992224
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8427-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052439
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75339
axoneme assembly	GO Biological Process Annotations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.43122
KDM5B	ENCODE Transcription Factor Targets	1.0	null
axoneme part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.15262
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Common cold	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.936
ZEB1	ENCODE Transcription Factor Targets	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1088
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1832
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
GSE207514,GSE207515_2_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46944
Prostate adenocarcinoma_PRAD_TCGA-CH-5744-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1483
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04178
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00449
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.909255
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ciliary cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.60655
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GAP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78409
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.935796
17483317-TableS5	GeneSigDB Published Gene Signatures	1.0	null
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.440776
Chronic Otitis Media	DisGeNET Gene-Disease Associations	1.0	null
Myocardial Infarction	dbGAP Gene-Trait Associations	1.0	0.020801
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6033-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	ENCODE Transcription Factor Targets	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52857
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13618
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4IJ-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.840776
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.216829
major	GeneRIF Biological Term Annotations	1.0	null
Kartagener Syndrome	DisGeNET Gene-Disease Associations	1.0	null
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47804
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20996
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92854
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Hypobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5445
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Newborn respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918677
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047994
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.925
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35484
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04251
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29127
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381379
PMC4595011-pgen.1005555.s001.xlsx-MITF_UP-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE240027,GSE240030_1_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72213
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69609
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02398
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KYO1	CCLE Cell Line Gene CNV Profiles	1.0	1.49813
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3857
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.22016
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11458
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_4_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03472
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
Extrapulmonary bronchus_CT1_ciliated cell of the bronchu	HuBMAP ASCT+B Annotations	1.0	null
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	1.0	null
nfe2l2_00000000_neonate_p3_lung_lof_mouse_gpl1261_gse29632	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.950001
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29815
SAGA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24423
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95052
VRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68677
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99622
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2158
Primary ciliary dyskinesia 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TE-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.908
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18269
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.925
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18697
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.29601
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01213
TFIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81218
hsa-miR-378h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DICER1_KO_GDS4504_586_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49712
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98405
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2038
VMRCRCW	DepMap CRISPR Gene Dependency	1.0	2.06769
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.46298
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
SLR23	Achilles Cell Line Gene Essentiality Profiles	1.0	1.68783
atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212761
disease	GWASdb SNP-Disease Associations	1.0	0.028982
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186087
hsa-miR-4526	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
FOS_01_99	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.51733
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30465
RUNX1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22219
spoke	GeneRIF Biological Term Annotations	1.0	null
Cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.309
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12830621-41467_2025_67611_MOESM11_ESM.xlsx-Sheet1-Suppl_Data-9_Common_differentially_up-regulated_genes_in_high_vs_low_Mecom_MECOM_mouse_KME_AML_cells_and_human_AML_from_4_public_databases_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14611
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28784
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053553
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22318
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17333
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09181
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910307
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Stromme syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4903
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	2.10744
Megagametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
HMGN3	ENCODE Transcription Factor Targets	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53472
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966494
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03298
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16578
ELN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24352
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Transcription export complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_TCF1-GeneSymbol_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14844
WNT_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
PCI-15A	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
LIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11225
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03587
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2395
OS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39488
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.00449
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37264
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.54429
G3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32539
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32503
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066123
PMC11237666-spectrum.03516-23-s0004.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.36097
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.961921
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05983
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JURLMK1	DepMap CRISPR Gene Dependency	1.0	6.88239
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.929
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839968
Intraciliary transport particle A	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41659
Perturb_9596_KO_Prox1_SRP176286	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.81764
abnormal male reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dexamethasone_mus musculus_gpl6105_gse44208	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95357
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5633-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80393
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6792-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78952
E2F4	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2135
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.240879
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51262
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.210549
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74593
OV7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.045
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.884179
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUG1N	CCLE Cell Line Gene Expression Profiles	1.0	2.03901
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94364
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19088021-supptable2	GeneSigDB Published Gene Signatures	1.0	null
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RFX5_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytoplasmic region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ciliary	GeneRIF Biological Term Annotations	1.0	null
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0215
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06231
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942276
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874689
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.052004
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.986125
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2299
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Tracheobronchial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
GSE161864,GSE161866_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88869
NANOG	ChEA Transcription Factor Targets	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854055
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02044
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95055
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0291
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
cellular component assembly involved in morphogenesis	GO Biological Process Annotations 2015	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14728
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94372
Human - Lung v2 (HLCA) - L5 - Multiciliated (nasal)	HuBMAP Azimuth Cell Type Annotations	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32443
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41398
restricted	GeneRIF Biological Term Annotations	1.0	null
mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_11_v_4_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69017
RNR2	Hub Proteins Protein-Protein Interactions	1.0	null
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67181
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920968
GSE210476_11_v_5_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ciliary shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3186
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4892
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33979
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
Fatty Liver	CTD Gene-Disease Associations	1.0	1.27224
placenta_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VASH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81614
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
REH	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.39269
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930831
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39904
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
abnormal spermatid morphology	MPO Gene-Phenotype Associations	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.538118
GTEX-XPVG-0626-SM-4B65B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83709
infertility	MPO Gene-Phenotype Associations	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30422
ABCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09711
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836929
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.996539
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	4.25416
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.394621
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
NUP188	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68355
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04117
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.969186
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STK11_knockout_278_GSE34866	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.00377
LPS141	DepMap CRISPR Gene Dependency	1.0	3.03882
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UT7	CCLE Cell Line Gene CNV Profiles	1.0	2.04971
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62015
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CORL88	CCLE Cell Line Gene Expression Profiles	1.0	1.60546
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
corolla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844965
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Orofaciodigital syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
Perturb_1813_KO_N4bp1_SRP255180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.24164
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-378	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17333
condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.381199
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	180.963
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18864
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864478
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88008
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01647
HS229T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08716
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886871
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841461
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875123
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62523
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.951
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966229
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.9596
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38723
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Delayed Speech And Language Development	DisGeNET Gene-Phenotype Associations	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE450	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07811
Cytoplasmic dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25406
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847951
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35782
KSR2_knockout_60_GSE17923	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.25498
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67769
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
HNRNPH1_02_08	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63743
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3685
PMC6275272-FEB4-8-1977-s006.docx-0-Supplementary_Table_S1_Downregulated_genes_under_MYC_knockdown_in_AMU-ML2_cells_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0281
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.263
ROS50	DepMap CRISPR Gene Dependency	1.0	3.82343
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19802
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23576
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
SP1	ENCODE Transcription Factor Targets	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2965
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.827772
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.906926
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.12288
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0329
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44175
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39863
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6419
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE117212,GSE117214_2_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.33464
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.08891
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08645
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.762
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915503
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07465
calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1483
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.30635
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6857
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Impaired Nasal Mucociliary Clearance	DisGeNET Gene-Phenotype Associations	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59539
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256568
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.455224
RAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18964
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921297
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918677
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
preweaning lethality, incomplete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974797
DA-62-QB27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.312951
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29046
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49112
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852867
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826491
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30907
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Respiratory Distress Syndrome, Newborn	DisGeNET Gene-Disease Associations	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
STAT1	ChEA Transcription Factor Targets	1.0	null
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.365348
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.917351
PLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1474
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853965
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917827
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADCY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69347
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04696
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.851085
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.862
Lung Diseases	CTD Gene-Disease Associations	1.0	1.05793
ZBED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77659
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dyskinesia	GeneRIF Biological Term Annotations	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
perianth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.812309
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1265
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950062
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6036
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29002
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	2.37907
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875482
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974233
GSE234340_3_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell projection organization	GO Biological Process Annotations 2015	1.0	null
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
EBF1	ENCODE Transcription Factor Targets	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.31273
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854055
MRPL55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61702
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74561
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861698
KNSTRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87021
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33413
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ENSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95037
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944458
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CLCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20837
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990685
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.936863
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anemia	DisGeNET Gene-Disease Associations	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4237
Respiratory system_CT1_lung ciliated cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
MEIS1	ChEA Transcription Factor Targets	1.0	null
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GOLGA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69522
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825587
CMLT1	DepMap CRISPR Gene Dependency	1.0	3.98695
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938804
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.890412
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.946398
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.10959
PMC2768459-6605275x4.xls-Hoja1-Supplementary_Table_S1_Differentially_expressed_genes_within_the_ESR1-positive_BRCA1_tumors_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67607
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0041
Rectum adenocarcinoma_READ_TCGA-CI-6623-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48512
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83329
biological_process	GO Biological Process Annotations 2015	1.0	null
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72883
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10873
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8706
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.783
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11486
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924734
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13933
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899195
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994517
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838548
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53613
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TBC1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49683
HT29	CCLE Cell Line Gene Expression Profiles	1.0	1.42641
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.3673
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Minor mitochondrial derivative	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.954661
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5573-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.680248
Nasal polyp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
Htk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	0.95326
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
Ciliary tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.36
Flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.86
SJSA1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32281
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.891845
protein binding	GO Molecular Function Annotations 2015	1.0	null
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.425
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.031202
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24498
Bronchiectasis	DisGeNET Gene-Disease Associations	1.0	null
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19294
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A821-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85634
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.173
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Water vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
LSM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13037
abnormality of the bronchi	HPO Gene-Disease Associations	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03304
Dextrocardia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.045
MYC	ChEA Transcription Factor Targets	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.09822
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84057
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7789
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.785607
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
ciliary part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.367388
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993295
Extrapulmonary bronchus_CT1_airway submucosal gland duct ciliated cell	HuBMAP ASCT+B Annotations	1.0	null
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	1.0	1.67755
Axonemal central apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.159
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.825706
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32666
Perturb_1686_OE_Mnx1_SRP373412	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6424977-41467_2019_9182_MOESM10_ESM.xlsx-MI-Symbol_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Velum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.849
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215928
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84116
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07936
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74249
SCC25	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49276
Respiratory system_CT1_ciliated cell of the bronchu	HuBMAP ASCT+B Annotations	1.0	null
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.263
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71435
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Primary Ciliary Dyskinesia	DisGeNET Gene-Disease Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61534
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-3660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Recurrent Sinusitis	DisGeNET Gene-Disease Associations	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
recurrent infections	HPO Gene-Disease Associations	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06917
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.2898
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04968
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925678
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55912
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.87803
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05058
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Radial spoke	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35356
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97808
CREBBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11044
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56872
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.86328
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.002
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41455
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13589
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24594
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40912
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8093
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44238
GABPA	ENCODE Transcription Factor Targets	1.0	null
MONOMAC6	CCLE Cell Line Gene CNV Profiles	1.0	1.32781
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPIB	JASPAR Predicted Transcription Factor Targets	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.667
ARPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1226
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TGFB2_KD_GDS4483_351_mouse_Embryonic palatal tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
rhinitis	HPO Gene-Disease Associations	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
X-linked panhypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48725
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
Familial adenomatous polyposis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA_01_131	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.25858
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
EGR3_01_212	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.22814
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.4684
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45998
OVISE	CCLE Cell Line Gene Expression Profiles	1.0	1.47279
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0283
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8536
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98238
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.512
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217166
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3637
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214727
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.967673
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953546
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23699
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Human - Lung v1 - L1 - Ciliated	HuBMAP Azimuth Cell Type Annotations	1.0	null
Lung bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
SLC45A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47119
Lung adenocarcinoma_LUAD_TCGA-78-7147-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49956
RH28	DepMap CRISPR Gene Dependency	1.0	2.48294
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051083
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	2.42647
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
abnormal sperm number	MPO Gene-Phenotype Associations	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1837
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44535
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22874
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925098
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925677
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.216109
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.430656
ME-16-XW76_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.345185
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02155
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053648
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11532
PML	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70391
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
SP in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984752
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	1.72511
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19408
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11084
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051363
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03495
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01153
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15294
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4177
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39863
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
FAM241B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38019
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93671
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.605372
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.874095
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85275
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0734
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58748
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998002
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21669
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
stigma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.572018
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973905
GSE200839,GSE233826_5_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85581
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2309
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
OCIM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57003
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	1.0	2.24595
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.15422
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78
Epididymal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63606
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29315
Sigmoid_Colon	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.044
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
microtubule bundle formation	GO Biological Process Annotations 2015	1.0	null
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2724
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.442418
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970463
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plant ovule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
HEL9217	CCLE Cell Line Gene Expression Profiles	1.0	1.38371
EE-02-BO83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.294473
Ovum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	2.36486
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.351408
gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362273
CARMIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13974
SET2	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05111
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13134
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21716
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05106
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4445	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23508
POU5F1	ChEA Transcription Factor Targets	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97521
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.55338
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.906576
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39699
Prostate adenocarcinoma_PRAD_TCGA-EJ-5521-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11776
PECAPJ49	DepMap CRISPR Gene Dependency	1.0	3.55922
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.945912
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal male reproductive system physiology	MGI Mouse Phenotype Associations 2023	1.0	null
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5597
Cholangitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.512
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.479
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923839
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64262
MRI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55618
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Ciliary plasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32762
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929832
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NKX2-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20531
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26241
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08326
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Cri-Du-Chat syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.561
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0224
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04493
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
HEL	CCLE Cell Line Gene CNV Profiles	1.0	1.9382
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TTYH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31623
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23824
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00987
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.310715
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929811
Retinoschisis_Retina_GSE5581	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.681893
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80532
GSE166308_1_v_0_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42803
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.35206
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
biallelic	GeneRIF Biological Term Annotations	1.0	null
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23758
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21707
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935265
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71854
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
IM95	CCLE Cell Line Gene Expression Profiles	1.0	1.86084
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	2.18508
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49866
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833045
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66574
BB-79-AG41_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228641
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
viral membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167856
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Otitis Media With Effusion	DisGeNET Gene-Disease Associations	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84562
SRSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95777
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A3LS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KALS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IGFBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06588
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866937
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18115
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11617
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.938625
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
Thymic stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82524
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35905
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
RFX5	ENCODE Transcription Factor Targets	1.0	null
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.66024
SP2	ENCODE Transcription Factor Targets	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46453
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.42019
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1293
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KARPAS422	DepMap CRISPR Gene Dependency	1.0	6.67789
Tracheal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
UACC812	CCLE Cell Line Gene Expression Profiles	1.0	1.66459
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60904
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.01531
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.4684
CEBPB	ENCODE Transcription Factor Targets	1.0	null
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0672
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44247
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33868
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.316
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4422
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.274811
Ciliated cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
RUNX1	ChEA Transcription Factor Targets	1.0	null
ATP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41444
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56861
SNX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35984
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear pore outer ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44284
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07212
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998934
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55616
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.71304
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38048
Fetishism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM16	CCLE Cell Line Gene CNV Profiles	1.0	2.47921
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23578
RMGI	Achilles Cell Line Gene Essentiality Profiles	1.0	1.14612
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
microtubule cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.578416
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.28858
pharyngeal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23272
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	4.07003
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.241
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3449
thus	GeneRIF Biological Term Annotations	1.0	null
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
cilia	GeneRIF Biological Term Annotations	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.4483
PMC7899452-media-5.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16943
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07576
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.44488
HEC251	DepMap CRISPR Gene Dependency	1.0	2.0236
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7396
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.498
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8116
CUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68495
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864167
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35043
SP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41998
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormality of the sinuses	HPO Gene-Disease Associations	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.95608
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
increased Sertoli cell phagocytosis	MGI Mouse Phenotype Associations 2023	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.9596
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67645
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.19934
22RV1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13871
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30027
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19515
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0862
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22809
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16175
abnormal germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16209
nucleus	GO Cellular Component Annotations 2015	1.0	null
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873169
H4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6153
PUS7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8546
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NQ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42553
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.19733
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-378c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Primary ciliary dyskinesia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.888
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1639
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11505
GSE198971_0_v_2_ncor2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59609
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13062
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.83713
16166195-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6068
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3378
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7203
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92546
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71481
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551298
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-0626-SM-4BOPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952375
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08425
Trachea_CT1_ciliated columnar cell of tracheobronchial tree	HuBMAP ASCT+B Annotations	1.0	null
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86258
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28569
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31387
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the respiratory system	HPO Gene-Disease Associations	1.0	null
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64231
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	3.083
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ciliary Dyskinesia	DisGeNET Gene-Disease Associations	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
10q22q23 copy number variation	WikiPathways Pathways 2024	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64948
Prostate adenocarcinoma_PRAD_TCGA-HC-7231-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835356
sperm	GeneRIF Biological Term Annotations	1.0	null
YB-83-AS93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.281919
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75062
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57363
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
TAF1	ENCODE Transcription Factor Targets	1.0	null
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE125219,GSE125221_3_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.91025
POLR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42772
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A541-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-422a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP8B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47289
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
MAP1S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56863
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.98856
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06154
ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489447
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29364
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01756
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24241
Human - Lung v1 - L2 - Ciliated	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11112608-BLOODA_ADV-2023-011512-mmc1.pdf-24-ZNF471_ZNF471	Rummagene Transcription Factor Associations 2026	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.893928
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41715
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18507
ARMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19684
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Respiratory Distress	DisGeNET Gene-Phenotype Associations	1.0	null
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3701
milder	GeneRIF Biological Term Annotations	1.0	null
Atelectasis	DisGeNET Gene-Phenotype Associations	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.902118
abnormal reproductive system morphology	MGI Mouse Phenotype Associations 2023	1.0	null
phenotype	GeneRIF Biological Term Annotations	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.126
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_3_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DOV13	CCLE Cell Line Gene CNV Profiles	1.0	1.39732
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1344
t47d	HPA Cell Line Gene Expression Profiles	1.0	0.922925
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07099
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.78599
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
molecular_function	GO Molecular Function Annotations 2015	1.0	null
A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.26209
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49117
LN464	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03014
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10541450-41419_2023_6165_MOESM3_ESM.xlsx-Normal-P53-STIC-Unnamed_3_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968731
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BCL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18962
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13088
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35091
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ITPRID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15805
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32743
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
RAD54L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9535
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8555
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561644
CARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77059
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31669
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0886
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.01512
cytoskeleton organization	GO Biological Process Annotations 2015	1.0	null
Visceral heterotaxy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.777
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76987
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42201
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ADNP_Deficiency - NULL MUTATION_GDS2540_691_mouse_E9 embryos - Heterozygous mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.049
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.852525
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3565
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39575
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842415
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63283
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920378
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99555
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866822
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850688
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
gastroenteritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.612011
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867018
H2BW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67712
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23538
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.163208
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916465
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.925678
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.894
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943346
C14orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60747
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3675
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.833
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26604
FOS	ENCODE Transcription Factor Targets	1.0	null
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52934
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2366
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cell projection	GO Cellular Component Annotations 2015	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
Perturb_1221_KO_Klf16/Maz/Sp1/Zbtb7a_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.89488
abnormality of immune system physiology	HPO Gene-Disease Associations	1.0	null
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.6342
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30974
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
High grade ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66486
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31342
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
oligozoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
APOBEC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22835
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CREBBP	ENCODE Transcription Factor Targets	1.0	null
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
NCIH2122	DepMap CRISPR Gene Dependency	1.0	3.93298
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30779
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Otitis media	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61165
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM217B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48737
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.88545
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.239
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.274811
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95928
TAF7	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5567-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TNNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6236
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tachypnea	DisGeNET Gene-Phenotype Associations	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QF-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-2626-SM-4JBJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77414
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-THRB_THRB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45386
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38815
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dilated Ventricles (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
Gametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136238_1_v_2_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SEMA5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32533
dorsal cochlear nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861251
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971466
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
SLC27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8402
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.493371
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU1	DepMap CRISPR Gene Dependency	1.0	2.82923
Perturb_11857_KO_miR301a_SRP131007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.28545
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02965
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905612
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
AA-23-FM46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.33562
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864922
GTEX-WY7C-2826-SM-3NB3Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05534
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50626
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6875
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854055
WIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54211
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47334
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08796
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-866-ENSG00000141956_PRDM15	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.048
GRK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Alkyl hydroperoxide reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.204923
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.186087
YMB-1-E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834644
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9421
cilium	GO Cellular Component Annotations 2015	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76005
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11084
Rectum adenocarcinoma_READ_TCGA-DT-5265-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
GSE120756_2_v_9_tet2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984749
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.013
LS513	CCLE Cell Line Gene Expression Profiles	1.0	2.4131
chr21_42509742_C_A_b38	GTEx eQTL 2025	1.0	1.14393
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80769
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99758
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC66A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33752
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48575
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5048
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98757
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gynoecium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.739266
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viral envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181524
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	2.02245
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spermary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.841029
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1191
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04061
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
LIME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30721
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915197
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31305
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TIMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45018
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1209
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7678
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05567
JHOM1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.8962
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42605
ChIP_ZFP42_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01955
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13021
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.027
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP3K1_knockout_245_GSE39240	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.27091
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.134478
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25739
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.773047
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24293
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0466
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.548
unique	GeneRIF Biological Term Annotations	1.0	null
Secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45203
Trachea_CT1_ciliated cell of terminal ciliated ducts of submucosal gland	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GSE211983_1_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52381
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61086
Choline	CTD Gene-Chemical Interactions	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90528
sinusitis	HPO Gene-Disease Associations	1.0	null
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058752
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05856
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054814
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27388
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.984424
SP2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3755
chr21_42476916_A_T_b38	GTEx eQTL 2025	1.0	1.98261
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16081
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
Extrapulmonary bronchus_CT1_airway submucosal gland duct ciliated cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10605
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0322
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01378
PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_2_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
myocardial infarction	GWASdb SNP-Disease Associations	1.0	0.597957
Bronchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893333
LYRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92673
Heart Diseases	CTD Gene-Disease Associations	1.0	1.19574
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853965
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61115
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15311
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5359
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHH2	DepMap CRISPR Gene Dependency	1.0	2.55201
LRRC41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47236
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72645
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48971
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43496
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45938
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20F-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKGI	DepMap CRISPR Gene Dependency	1.0	2.25808
Extrapulmonary bronchus_CT1_ciliated cell of the bronchu	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
ZFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86602
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04356
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Major mitochondrial derivative	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.842
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
FBXO31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6745
HCC1359	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38618
inherited metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.23911
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.019005
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3791
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12848
FAM171A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69833
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20460542-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_7671_KD_NBAS_SRP267245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.97936
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.884042
HCT116	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.8749
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08717
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898742
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854055
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26718
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89349
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.02578
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11286
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15535
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5423
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.198279
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90697
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048207
motile cilium	GO Cellular Component Annotations 2015	1.0	null
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.379954
Rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.476
Axonemal outer doublet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.935
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.76971
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02168
C22orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.791
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Joubert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
UBA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42891
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947002
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.947427
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UOK101	Achilles Cell Line Gene Essentiality Profiles	1.0	2.22872
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125403_3_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.553768
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.201071
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21798
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
decreased fertility	HPO Gene-Disease Associations	1.0	null
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02947
RBM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13531
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal respiratory system morphology	HPO Gene-Disease Associations	1.0	null
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00931
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8003
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77299
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3064
Sinusitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.23
bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Implantation fossa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.307
Sputum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
Sex chromatin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.126
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pharyngeal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
KDM2B-26808549-CHIP-SEQ-SUP-B15-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32839
Posterior fossa ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bronchitis, Chronic	DisGeNET Gene-Disease Associations	1.0	null
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.148
Cancer cell_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Perturb_2011_KO_Cd40lg_ERP130522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.2784
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
GA-10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37994
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16288205-GeneTable2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.99209
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25922
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3712
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27926
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
TALL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88857
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48971
NOSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58368
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41397
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962748
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4760-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12153
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22392
SMAD3-22036565-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.73231
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27205
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ovariole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
SLC35B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24443
Human - Lung v2 (HLCA) - Finest - Multiciliated (nasal)	HuBMAP Azimuth Cell Type Annotations	1.0	null
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838403
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.853859
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11547
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40077
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Trachea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.548
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TM9SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84777
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34849
Coughing	DisGeNET Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825415
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08831
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04443
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.920946
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9398
RBM48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34538
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.662
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291365
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948336
FOXP2	ChEA Transcription Factor Targets	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.929319
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.570262
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203699
outer CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895709
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	1.88844
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04477
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051967
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863186
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19828
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29836
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18678
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06481
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.924846
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39751
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10026
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40568
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43988
A-CA-04-2009(H1N1)_36Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.3829
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02591
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96176
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
SELENBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2134
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25545
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28342
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.861
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.2173
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32855
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HUP-T3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.986083
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212936
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4685
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.198325
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56303
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
GSE201401_2_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr21_42509404_T_A_b38	GTEx eQTL 2025	1.0	4.04528
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36005
WASF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57667
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8384902-mmc7.xlsx-105_ASCL1_Direct_repressed-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83146
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12054
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31995
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.614
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22097
18794137-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.043232
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.995
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984122
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MYC_Activation - 24 hours_GDS2025_726_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2231
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-378b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
HS281T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.39367
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07438
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.981147
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rhinitis	DisGeNET Gene-Disease Associations	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.328
EJM	DepMap CRISPR Gene Dependency	1.0	2.8262
TE15	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.64679
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0183
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1314
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.83203
TRIM21	Hub Proteins Protein-Protein Interactions	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918718
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94452
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
SNB75	DepMap CRISPR Gene Dependency	1.0	3.14936
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963118
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
NCIH2110	DepMap CRISPR Gene Dependency	1.0	3.26482
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.217
Microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.154
UD-16-YL39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.532769
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05985
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829017
H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67958
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.994294
spermatid development	GO Biological Process Annotations 2025	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62296
8305C	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73101
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.395735
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.6606
Prostate adenocarcinoma_PRAD_TCGA-J4-A67L-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96722
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.942015
CREM	ChEA Transcription Factor Targets	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92955
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37819
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04718
Congenital Pectus Excavatum	DisGeNET Gene-Disease Associations	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903479
SNUC4	CCLE Cell Line Gene Expression Profiles	1.0	1.44732
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.678677
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
motile cilium	GO Cellular Component Annotations 2025	1.0	null
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.297418
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88456
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflagellar rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928545
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841102
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838878
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918677
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Kidney Chromophobe_KICH_TCGA-KN-8436-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03687
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J3-01A-12R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
radial	GeneRIF Biological Term Annotations	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21561
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0814
hsa-miR-378e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
E2A-27217539-CHIP-SEQ-RAMOS-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.7636
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.66648
radial spokehead	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18081
carbamoyl-phosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.894
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ADAM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80357
metal metabolism disorder	GWASdb SNP-Disease Associations	1.0	1.16904
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0623
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43074
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.887
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889927
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827759
petal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.871061
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5143_KO_Ring1B_ERP008873	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.77193
Perturb_8587_KO_Adnp_SRP063269	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.8271
Primary ciliary dyskinesia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.132
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2642
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76367
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31198
GSE179031_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17277_KO_Kdm1a_SRP185978	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.41567
PHF8	ENCODE Transcription Factor Targets	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.726
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043401
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE169356_0_v_5_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3001
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957098
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88463
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Nrd1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
SNU761	DepMap CRISPR Gene Dependency	1.0	2.24296
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42332
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17921
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7152
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.188
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36171
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.941809
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333763
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.19509
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10434
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985305
BRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37994
cytosol	GO Cellular Component Annotations 2015	1.0	null
ut1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
Learning Disorders	CTD Gene-Disease Associations	1.0	1.1485
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CDC14A	Hub Proteins Protein-Protein Interactions	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854055
RBBP5	ENCODE Transcription Factor Targets	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3233
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.24958
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10116
microtubule bundle formation	GO Biological Process Annotations 2025	1.0	null
Aiolos_NULL MUTATION_GDS3473_572_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868827
chr21_42486241_G_C_b38	GTEx eQTL 2025	1.0	1.93484
CNOT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20986
SULT1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
COX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64307
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.984595
SMARCC1	ENCODE Transcription Factor Targets	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.857014
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.977639
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus	GO Cellular Component Annotations 2025	1.0	null
Bronchial mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915566
monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
respiratory tract infection	HPO Gene-Disease Associations	1.0	null
IFI30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17322
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.08897
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
OE-E6/E7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16297
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48241
Kartagener syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.525
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
SIN3B	ChEA Transcription Factor Targets	1.0	null
abnormal sperm physiology	MPO Gene-Phenotype Associations	1.0	null
abnormality of the immune system	HPO Gene-Disease Associations	1.0	null
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterus-ciliated epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.343
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C99	DepMap CRISPR Gene Dependency	1.0	2.06625
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.366
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56181
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FSP27_KO_GDS3768_514_mouse_White adipose tissue  (WAT)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HS863T	CCLE Cell Line Gene Expression Profiles	-1.0	-3.13925
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32195
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TCF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98237
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67722
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9147
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100378_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17272
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18736
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15106
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965941
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.27776
Ovary	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	5.72392
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Investment cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
RAD21	ChEA Transcription Factor Targets	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.171296
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SUPT5H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.1279
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16967
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33004
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839523
PMC11237666-spectrum.03516-23-s0004.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
Agenesis	DisGeNET Gene-Disease Associations	1.0	null
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03578
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NACAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85549
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054973
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50877
MYC-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Inner acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.67
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88172
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34198
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.317798
GSE75976_3_v_4_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44611
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.733
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45773
OE19	CCLE Cell Line Gene Expression Profiles	1.0	1.7314
CCNT2	ENCODE Transcription Factor Targets	1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ES1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SCS214	DepMap CRISPR Gene Dependency	1.0	4.22145
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q1-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_11_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854055
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130766
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12569
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3257
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Atrioventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.919726
MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A673	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.10694
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22487
SK-LMS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19P-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04053
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.263
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29703
GSE218819_2_v_1_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970821
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24541
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOS_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BRCA1	ENCODE Transcription Factor Targets	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56653
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.814
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964326
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947018
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77537
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.324
MEOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41294
MYD88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52519
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.80971
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23496
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.61967
Polynesian Bronchiectasis	DisGeNET Gene-Disease Associations	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.665
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7649
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4835
ZNF514	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58565
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANC1005	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32102
OBF-1_NULL MUTATION_GDS3473_571_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00962
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40124
PRDM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29979
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959884
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20951
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.8773
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DV-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
Bronchiectasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.541
ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08766
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3222
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	1.53033
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.42854
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
Corpus epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
denotes	GeneRIF Biological Term Annotations	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
Perturb_5192_KO_Nanog_SRP116119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.55009
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02295
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87731
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
microtubule-based process	GO Biological Process Annotations 2015	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	2.32687
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49872
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
TO175T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62711
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848924
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.824
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04295
GSE211983_1_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831864
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.847622
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05592
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862956
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8555
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50816
NDFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8045
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.947033
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HT-1080	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2448
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FTSJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14468
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30278
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913829
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62875
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07648
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853965
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.0621
down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388538
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2723
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916127
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01986
GTEX-N7MS-0011-R7a-SM-2HMKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899811
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
PANC1005	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.75406
293-F FreeStyle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924734
Oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.855
Ampulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.1828
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28931
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.91297
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
axonemes	GeneRIF Biological Term Annotations	1.0	null
Perturb_15147_KD_EHF_SRP081174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.64595
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36006
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74721
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63805
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.15243
Get-1_Deficiency_GDS2629_161_mouse_embryonic skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5779
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053702
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GB-57-XV52_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.561982
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38148
cilium assembly	GO Biological Process Annotations 2023	1.0	null
OSBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43868
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SCN4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23891
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Trachea_CT1_ciliated columnar cell of tracheobronchial tree	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.575616
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210662_3_v_0_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19596
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90336
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68466
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41578
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875071
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infertility	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10284
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5692-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900308
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139948_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hedgehog signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55711
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.363393
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.847
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923159
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.96719
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_11_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
SERINC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92682
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17809
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57121
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.75372
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.651
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20289
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839072
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5287
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of divalent inorganic cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.417316
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.614636
decreased male germ cell number	MPO Gene-Phenotype Associations	1.0	null
THP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24181
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87445
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE137914_4_v_1_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
PABPC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37406
virion part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070749
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9765
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.05471
RCOR1	ENCODE Transcription Factor Targets	1.0	null
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47027
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Animal cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
HSC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44917
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
KYSE510	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.57455
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45857
heart_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16949
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36684
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1757
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99232
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61829
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925024
ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927169
Paranasal sinus disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.214
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66951
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00533
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23298
SNU1076	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14149
Serous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14895
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73724
Hypertrophy	CTD Gene-Disease Associations	1.0	1.13621
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.644
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55946
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.861953
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57191
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23467
hsa-miR-378d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64073
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.12907
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56885
vascular disease	GWASdb SNP-Disease Associations	1.0	0.071637
BACH1	ENCODE Transcription Factor Targets	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5032
PMC4486168-pone.0131961.s006.xlsx-Sheet1-ARID3B_Down_Regulated_Genes_ARID3B	Rummagene Transcription Factor Associations 2026	1.0	null
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52393
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4176
EE-03-SG02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.419604
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985945
Perturb_2635_KD_TRIM46_SRP323434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.35067
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25569
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76819
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33262
PMC8298514-41467_2021_24813_MOESM22_ESM.xlsx-RELA_H3K27ac-SYMBOL_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17568
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30422
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.073
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54352
SIN3A	ENCODE Transcription Factor Targets	1.0	null
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
magnesium	GAD Gene-Disease Associations	1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Respiratory mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
KCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30216
MHH-PREB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57191
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of reproductive system physiology	HPO Gene-Disease Associations	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12885
PMC8299217-mmc3.xlsx-FOXJ1_high_Ciliated_Cells-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
H2BK120ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nuclear pore linkers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
PMC10645393-jci-133-169200-s102.xlsx-Table_S14_AR-V_DNA-PK_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
ATF1	ENCODE Transcription Factor Targets	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856204
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC364	Achilles Cell Line Gene Essentiality Profiles	1.0	1.50833
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864449
GATA1	ChEA Transcription Factor Targets	1.0	null
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41535
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120413,GSE120447_4_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.259839
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45692
HAE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
Situs inversus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.806
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.972215
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32279
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
TRIM28	ChEA Transcription Factor Targets	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95298
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05384
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
c91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39569
LAMTOR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55588
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8299217-mmc3.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital Absence Of Spleen	DisGeNET Gene-Disease Associations	1.0	null
Respiratory epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15215
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236332
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SPI1	ChEA Transcription Factor Targets	1.0	null
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984122
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96978
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RCOR1_02_204	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64636
male infertility	MGI Mouse Phenotype Associations 2023	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05631
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15749
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149943_1_v_3_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Trachea-ciliated cell	Tabula Sapiens Gene-Cell Associations	1.0	7.42724
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86239
VARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74962
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.894788
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57895
PIMREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72641
Transplanted Heart Complication_Myocardial tissue_GSE582	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.13953
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.8365
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.919726
Subsynaptic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7052
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
16288205-GeneTable3	GeneSigDB Published Gene Signatures	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.604931
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11817
abnormality of magnesium homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.02123
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96174
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal spermatid morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H345	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15630_KD_Ctnnb1_SRP130920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.3999
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.166167
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12700831-41594_2025_1680_MOESM4_ESM.xlsx-D9_MC_Hits_2_5FC_CRAPomeFilt-Mapped_Gene_Symbol_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36756
Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16023
cilium	GO Cellular Component Annotations 2023	1.0	null
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.924
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329727
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.34293
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38568
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28703
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Halitosis	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987166
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940409
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IRAK4_Deficiency_GDS2641_653_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
POLR3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21838
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16153
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993885
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GLUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10469
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Situs Inversus Totalis	DisGeNET Gene-Disease Associations	1.0	null
Cerebritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
WIL2-NS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.01814
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361901
hsa-miR-4279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.729
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
STEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45195
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.966699
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	1.57833
hsa-miR-378i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
NFYB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05292
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12558
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23467
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.156659
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06265
PA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43962
cilium assembly	GO Biological Process Annotations 2025	1.0	null
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SIHA	DepMap CRISPR Gene Dependency	1.0	2.25359
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69092
Headache	DisGeNET Gene-Phenotype Associations	1.0	null
cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.561358
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
GSE184475_1_v_0_il21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K029AX	DepMap CRISPR Gene Dependency	1.0	3.28023
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02155
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5696
FGF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71699
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.08296
NR2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06011
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	4.17023
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.918677
SUM185PE	DepMap CRISPR Gene Dependency	1.0	3.44771
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1357
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913637
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.959602
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95228
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
EFE184	DepMap CRISPR Gene Dependency	1.0	3.89368
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93399
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943642
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23467
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.846137
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.310652
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
ETS1	ENCODE Transcription Factor Targets	1.0	null
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.234
GTEX-XV7Q-0526-SM-4BRWR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
ZFP82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58555
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21689
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.1796
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3889
PMC7899452-media-4.xlsx-Early_Resp_FOXJ1_high_Ciliated-Unnamed_6_FOXJ1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.916106
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48326
MTA3	ENCODE Transcription Factor Targets	1.0	null
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42107
GSE214823,GSE214824_4_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36798
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906103
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	1.96549
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36626
PGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43494
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01118
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.165932
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72187
SETD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10483
PTP4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81906
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46545
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
OVMANA	CCLE Cell Line Gene CNV Profiles	1.0	1.53031
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.25807
RT112	CCLE Cell Line Gene CNV Profiles	1.0	1.60368
abnormal reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.982653
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829061
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13827
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
SNU5	CCLE Cell Line Gene Expression Profiles	1.0	1.6955
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068126
GTEX-QMRM-0626-SM-447BQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
STAT3	ChEA Transcription Factor Targets	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43674
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59266
GTEX-T2IS-1026-SM-32QP1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887055
Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A3PO-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.26171
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4613
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.08726
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4154
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oviduct epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13647
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12246
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38081
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
Outer dynein arm docking complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.394
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29874
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48383
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26457
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.88
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33477
KINGS1	DepMap CRISPR Gene Dependency	1.0	3.97761
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vitiligo	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.988
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909089
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56597
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39836
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the head	HPO Gene-Disease Associations	1.0	null
AGO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77238