association	dataset	threshold value	standardized value
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76627
HEXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07638
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
NEK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85331
PFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05981
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29559
XRCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12926
Myelocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32749
ADD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
Barrett's esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869799
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.20827
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53248
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.77149
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MutLalpha complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
CBARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84944
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33711
Perturb_8813_KD_YAP1/WWTR1_SRP284279	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.23033
CRCGN012_HEPG2_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25656
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02193
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930352
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10244
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99977
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96516
ZBTB22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32946
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27183
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66705
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17244
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1915
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9065
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904186
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3688
SK-N-DZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
A253	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.06203
CTDSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88443
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14777
Rectum adenocarcinoma_READ_TCGA-G5-6572-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02472
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13583
CRCGN015_HEPG2_48H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1942
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82651
GRB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63744
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60465
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85372
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37802
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80208
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998441
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46199
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36284
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06615
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38731
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28943
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE5109	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.992816
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4787
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68375
Perturb_2337_KD_WBP11_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.73975
Acute megakaryocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1954
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59539
wt1_17088532_huvec_lof_human_gpl570_gds2010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.448388
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869799
TMEM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28682
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58428
CRCGN015_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3707
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00017
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3176
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35586
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13481
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68444
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
IFI35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45497
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5068
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.50055
CRCGN013_HEPG2_24H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52364
TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.863942
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.983757
H2804	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.0501
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63683
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849543
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95491
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6823
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67716
SPATA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96548
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
AASS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
CRCGN008_HEPG2_24H:O16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73765
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.70429
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43052
e2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80614
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19469
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.48058
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838951
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.91345
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46514
Perturb_2315_KD_MED9_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.21495
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0311
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40748
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13158
Perturb_12338_KD_TFEB_SRP226507	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.80207
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21085
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37905
Perturb_2306_KD_DDX3X_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.72836
CPSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25078
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.27425
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89217
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45983
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Oligodendroglioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
SIRT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30091
PMC9805873-Supp_Data.xlsx-dCas9-SALL1-SDS3_SEL1L_pool-id_SALL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27148
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
SCC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09835
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830379
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09465
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07383
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.45127
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77363
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77959
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862546
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
pancreas_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15429
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49188
RTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81862
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5281
Perturb_2304_KD_CDC73_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.72825
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74357
MutLbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.148
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90845
CRCGN015_MCF10A.TP53.M_24H:N08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02365
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48277
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40268
Perturb_2335_KD_SON_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.94296
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56868
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7984
KAT2B_02_184	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.43296
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08666
COMMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37789
HRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37959
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36719
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43368
Urinary bladder cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0896
ASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
SHANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40561
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7571
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86404
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32619
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
OSC-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35102
TMEM209	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46901
Acute Myeloid Leukemia_LAML_TCGA-AB-2966-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23798
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
u87	HPA Cell Line Gene Expression Profiles	-1.0	-1.45928
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7435
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.930805
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1683
CRCGN010_HEPG2_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16495
MYH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44772
DERL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79353
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838309
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848187
Mesothelioma_MESO_TCGA-SC-A6LR-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EW-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9156
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86638
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34728
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
Centriolar satellite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18979
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10885
GTEX-QDVN-0526-SM-48TZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07728
BATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62376
TMEM184A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27959
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83122
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24042
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF358	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30203
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88919
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08859
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35788
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876549
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04153
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74007
Perturb_15812_Mut_RP2_SRP255721	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48973
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28427
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909158
IRF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40249
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32597
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34057
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
Perturb_6487_OE_MDM2_SRP302203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.52169
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7312
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913596
BARX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22815
NCI-H526	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30471
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
BICDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40513
HSP90AA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33833
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.70743
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AAAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47119
HAGHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48327
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39965
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83252
5637 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52089
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8117
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26672
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.16203
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.10801
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41596
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3495
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58264
ABL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32755
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908417
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0559
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67655
C18orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51912
SMARCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66486
SMARCAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17038
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01802
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61496
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49234
OCI-AML2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0734
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985283
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891755
GAMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53814
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2047
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944687
CRCGN017_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3567
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47449
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910717
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76925
ASAP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
CHEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88769
Alzheimer's Disease_Entorhinal cortex_GSE5281	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.62133
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57756
ZNF398	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32648
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80087
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62397
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15625
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17546
TSC22D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69558
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91765
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77689
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966357
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87238
Perturb_2325_KD_SF3A1_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.0247
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66369
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26068
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11423_KD_AR_SRP324259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.3147
Perturb_2760_KD_CBX3_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.89711
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Myeloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59733
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2998
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66411
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842271
CGNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18736
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM128	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71224
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950117
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
Perturb_4908_OE_SNCA_ERP129142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05659
SMIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05241
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941886
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5348
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61098
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12221
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50116
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29118
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31202
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03144
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43855
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14913
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.11461
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93334
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
SRI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41522
BNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3401
SF126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96865
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903522
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27861
Primary ciliary dyskinesia 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.301
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87266
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57125
ZDHHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75209
AFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80874
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
PL-21	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00877
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11566
MAN2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82602
SLC10A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72659
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
STC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46208
TOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64595
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.51039
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86494
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2685
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3602
TP63	ChEA Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96708
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76715
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64541
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8463
PLEKHG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57965
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01833
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29915
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11716_KD_GATAD2A_SRP194625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.5305
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70273
Lung adenocarcinoma_LUAD_TCGA-MP-A4TJ-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57163
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10176
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50366
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61054
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ADM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27698
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IF-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98808
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47476
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888223
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34747
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45971
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87622
BE-07-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.368917
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76447
Perturb_7466_KD_ARIEL_SRP136083	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.964
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48172
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02765
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70584
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
OCI-M2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.77
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06032
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89667
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09679
RABEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06203
NUAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60304
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05071
PCNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5468
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40442
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UT-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
Perturb_17036_KD_RUNX2_SRP265978	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.36599
APPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13722
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3216
patu8988t	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ARF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83908
CEBPZ_02_118	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.11548
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43729
Perturb_2318_KD_PRPF8_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38407
Perturb_12358_KD_RBMX_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.87116
Perturb_2310_KD_HNRNPC_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.9086
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10976
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53452
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908417
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41382
ZNF572	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36283
GTEX-T6MO-1426-SM-4DM73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892516
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02765
PPP2CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5025
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4373
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Perturb_313_KO_CARM1_SRP279319	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78922
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36129
PRKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33516
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0896
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93165
KIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57961
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02031
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90825
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46028
Perturb_773_Mut_ACLY_SRP403241	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.91441
ZFYVE19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69971
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74785
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89201
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.687
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04849
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30403
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10751
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926171
u26684	HPA Cell Line Gene Expression Profiles	1.0	1.24107
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.11443
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46846
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38344
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959667
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966648
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829079
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38681
Perturb_2307_KD_DDX3X_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.66828
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86735
urinary bladder	HPA Tissue Gene Expression Profiles	-1.0	-1.20119
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
KDR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75817
CRCGN015_MCF10A_48H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.12835
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2G_02_130	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.20163
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85074
APP	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51667
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7996-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29005
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLB-985 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
CCNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63023
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14975
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03395
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895941
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98489
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84813
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90492
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7752
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1651
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.277
NSUN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72124
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
496100314_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25939
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4075
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59331
Immature cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4102
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
BAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16783
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6005
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6641
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04578
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15832
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1392
CRCGN014_HEPG2_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42627
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32488
NDUFA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81253
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TSPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25941
ZNF799	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87542
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.247
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47001
SLC41A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33273
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39108
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907527
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949413
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68569
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21226
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60282
H3-3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95405
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96454
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SKOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22509
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1278
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4031
GSE213228_1_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0976
GSE213228_4_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4394
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45477
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
CRCGN016_MCF10A.WT.HP_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13686
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07254
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83332
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
PDE5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.20535
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82707
MV4-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
IL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16093
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53292
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26258
CRCGN017_MCF10A.WT.HP_24H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0829
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
TBC1D13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31395
LU-65	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TADA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69777
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03311
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02765
an3ca	HPA Cell Line Gene Expression Profiles	1.0	1.20515
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844884
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.222
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68509
ANKRD34B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32262
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
CDC42EP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69695
Perturb_2322_KD_RBMX_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1257
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49168
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58285
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4811
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97456
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4181
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72399
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
IL17RD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15266
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43557
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21703
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950117
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34783
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1826
BCORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65478
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6171
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02031
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
MRPL45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95001
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDC42SE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54094
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965128
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3577
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73701
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
KANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37854
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07322
Perturb_18485_KD_CAV1_SRP251283	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.82342
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
B3GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68735
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20248
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58217
PARP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68379
RBM22_02_92	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.0
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10693
ARF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4165
GPATCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62383
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50985
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
AP3M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28967
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12667_OE_MX2_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.08415
ANP32D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11712
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
OXNAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09164
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55878
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24412
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44255
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATAD3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00567
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57637
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59275
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
CRCGN015_MCF10A_48H:F12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01139
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46146
POLR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04244
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25832
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00861
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3445-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15255
ZDHHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62961
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75712
CARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47477
Perturb_14114_KD_ATF7IP_SRP156289	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42491
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.48631
CRCGN014_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5176
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22068
rpmi8226	HPA Cell Line Gene Expression Profiles	-1.0	-1.45928
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48801
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61705
KIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84455
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36672
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16338
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.825186
NPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55266
PIGU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47659
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35749
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10176
CRCGN008_HEPG2_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53915
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_FOXJ2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91884
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66628
PQBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39178
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Z8-0226-SM-4AD5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843221
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965128
Perturb_3958_KO_GSDMB_SRP350967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.73473
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76292
CRCGN013_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85481
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05784
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99444
CHMP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22219
CWC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69045
MYH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4532
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01172
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95285
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SO-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
PBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29535
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.88
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5415
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.13
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55069
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6176
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42372
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90376
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4493
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00772
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hela	HPA Cell Line Gene Expression Profiles	1.0	0.886779
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1848
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01689
WTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52916
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00024
Perturb_10674_KD_PLAG1_SRP332281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.15791
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6602
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
UBA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75001
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89686
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4756-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01549
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73175
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3275
Perturb_2316_KD_PRPF31_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.70625
TAF1	ENCODE Transcription Factor Targets	1.0	null
KDM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10054
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42145
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YWHAG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75031
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75102
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_6624_KD_DDX5_SRP237546	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.59938
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92527
GOPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7943
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21527
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23239
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59255
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6066
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853377
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM178A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
B3GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87494
SBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80218
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
MAGEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27555
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24638
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10409
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14774
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HW-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05472
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53241
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56842
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45907
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41108
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3162
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33669
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFKBIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80646
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986762
WASHC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53296
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02267
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A496-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15219
Astrocytoma_CNS - Brain (MMHCC)_GSE4290	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40505
lung	HPA Tissue Gene Expression Profiles	1.0	1.24912
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urinary bladder carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1925
MutLgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
YJU2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65728
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_2330_KD_SNRPB_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.44868
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57969
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GCLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49046
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824735
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14022
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38296
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06219
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853815
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07498
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2816-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89408
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context3-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CNIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87226
H2461	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1584
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21102
RAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90802
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1378
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93126
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34542
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33076
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14479
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98306
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16395
HPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7377
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45972
TMEM109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33455
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84285
TE-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81585
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
hsa-miR-4708-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82403
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86192
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31497
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839355
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07842
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NOP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03072
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02703
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07723
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.05547
TMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2984
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2857
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24292
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6493
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
FOSL2	ENCODE Transcription Factor Targets	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5801
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34185
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35832
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0105
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54207
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85905
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5913
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58331
DCUN1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16985
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14266
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42905
FBXO34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85773
DNAAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19908
Megakaryocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.22625
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51369
OXCT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52027
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	0.891631
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	0.971034
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3634
TRUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90351
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33087
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CELF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51352
SH3BGRL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52884
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	GTEx Tissue Gene Expression Profiles	1.0	1.00838
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98969
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97774
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83918
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40401
SART3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14623
DTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61969
PRKAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18095
NCI-H2110	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
hsa-miR-600	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SLC25A45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92729
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SYNCRIP_02_10	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47544
CHST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80115
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38169
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40134
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921123
PDPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21778
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5361
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0961
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73198
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08943
heart_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9202
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
HTR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50165
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7088
TGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4396
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43486
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.211679
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853488
Perturb_14085_KD_GAS41_SRP110132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00867
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2734_KD_BCKDK_SRP298085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.09701
REST	ENCODE Transcription Factor Targets	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-1.11586
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45959
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.241
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97672
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34052
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885806
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
ERBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02293
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75357
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13744
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.39239
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.97118
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.2002
TMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61743
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18923
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24521
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4691
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8687
MTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.29368
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96801
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63687
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992905
SLC43A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03362
SFXN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839355
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27677
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72112
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47356
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
C2orf74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60171
KPNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.257
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13676
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71473
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14349
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32121
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8316
TCF3	ENCODE Transcription Factor Targets	1.0	null
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2899
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0844
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87094
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
CRCGN013_HEPG2_24H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33752
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32493
t47d	HPA Cell Line Gene Expression Profiles	-1.0	-0.883148
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36934
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18245
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55223
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59497
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838742
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59231
CRCGN016_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04316
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87672
NFATC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99758
BL8482 (AAK1)	NURSA Protein Complexes	1.0	null
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28437
MEG-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68426
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50603
CRCGN015_HEPG2_48H:I23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18721
CYP27C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77375
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66227
RAD23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77097
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70347
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2309
ERP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
CRCGN015_MCF10A_48H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.12056
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898617
Trachea-ciliated cell	Tabula Sapiens Gene-Cell Associations	1.0	5.45927
SPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38274
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7491
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27207
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37121
Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.705
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90599
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831199
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44467
Perturb_12681_KD_MYCL_SRP109645	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.82195
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.042
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
Perturb_2303_KD_BRCA2_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.59004
GGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02932
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74308
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84392
cilium	GO Cellular Component Annotations 2025	1.0	null
THP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44754
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29099
GTEX-S341-1326-SM-4AD72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26092
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70563
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37861
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3179
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.98
HOXB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32092
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
RAB25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50808
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990817
KG-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892069
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3316
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49858
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.68933
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02331
SEMA3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54402
ZNF384_02_203	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.08746
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831199
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5839
UACC-812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26109
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32617
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951593
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5331
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8597
Perturb_2312_KD_LUC7L2_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.73173
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29522
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
TMEM214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8733
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43654
CTNNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84713
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0909
FAM83D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54705
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976519
SC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44441
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19533
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02774
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63045
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15389
Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27061
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.188
USF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80094
RNF149	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5899
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07529
ACSM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27898
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KD-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86025
SAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.113
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86723
Acute Myeloid Leukemia_LAML_TCGA-AB-2858-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52743
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15671
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64818
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888733
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_2334_KD_SON_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.34076
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	2.24804
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34646
UMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76695
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27193
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19589
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.818
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18391
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21334
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915126
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16181
Adrenocortical carcinoma_ACC_TCGA-OR-A5J6-01A-31R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84338
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72312
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.56624
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28021
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68552
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31585
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8494
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34395
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
CNNM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88842
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36805
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KLF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86836
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60941
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14458
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76373
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38034
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83474
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9609
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53931
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78798
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9613
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855482
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.65057
hsa-miR-3664-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MOSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08974
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2773
CHCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90448
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7384
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
HRH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34024
CRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12108
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE234647_1_v_3_regorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7162
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39053
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842363
PRSS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20176
Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133516_5_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12364_KD_SON_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.78209
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27769
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
DPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36374
Tumor necrosis factor receptor superfamily complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39519
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14331
NUTM2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57173
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28102
mRNA_CBX8_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831199
CRCGN013_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19605
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.50198
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843183
RWDD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58704
HACD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56466
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.876915
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35442
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17744
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91829
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4511	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28102
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.20147
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51726
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19845
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.48147
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86572
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.46581
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
CRCGN014_HEPG2_3H:I22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31982
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07952
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15189
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.452
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NIBAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21541
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46355
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92467
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
DUXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13744
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02458
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:B12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02465
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876648
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5921
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18321
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966648
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60521
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54361
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15277
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nfe2l2_00000000_neonate_p3_lung_lof_mouse_gpl1261_gse29632	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.519255
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
Megakaryoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.141
Perturb_2314_KD_MED9_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.72164
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52375
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72991
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19379
WDR62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74021
POLR2A	ENCODE Transcription Factor Targets	1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8904
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
CAMKK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58892
MOLM-16 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.407
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27649
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14015
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0065
MBTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45213
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
C8orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38236
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81946
CRCGN015_MCF10A.TP53.M_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04857
ACTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06893
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.925
CRCGN013_HEPG2_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11614
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.9952
PDZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8817
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908417
ALG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75649
Perturb_563_KD_MYCN_SRP158473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.95419
BACH1_02_188	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62803
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40166
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37028
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1364
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65187
hsa-miR-4639-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998132
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0226-SM-2XCBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831492
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91977
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-1.20119
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30346
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19285
PMC12515692-MOL2-19-2882-s001.xlsx-Phosphoprot_AKT1_AKT2_KD_vs_SCR-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31205
Perturb_2780_KD_HECTD1_SRP109301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26537
FOXI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41143
ITGB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79068
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25035
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86957
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H4C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.70545
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975567
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
H2AC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72036
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9154
NIPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55003
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55261
Perturb_2301_KD_BRCA1_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.62281
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7519
H1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72244
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13941
Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2534
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58128
SIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40425
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.02345
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85587
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EIF4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49434
CRCGN008_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10245
ICE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43479
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11926
Perturb_9354_OE_PIK3CA_SRP158425	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.55547
GGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13346
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63317
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92072
CERS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49463
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843186
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17868
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
OCI-M1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.953
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35114
YOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87353
HMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.18509
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1274
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6269
Premonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05446
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03634
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9387
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897249
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97447
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COQ7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96846
NR3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5293
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7258
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992169
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37142
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B4GALT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5352
capan2	HPA Cell Line Gene Expression Profiles	-1.0	-1.45928
Prostate adenocarcinoma_PRAD_TCGA-HC-A8CY-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22585
Perturb_2299_KD_AQR_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.3787
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.07319
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0162
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827619
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73922
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55154
CRISPLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73289
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908417
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81289
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13031
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04245
Perturb_2311_KD_HNRNPC_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.47314
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69133
SDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.15967
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53928
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831958
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935812
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01246
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27519
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
RASL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86942
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49699
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF519	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75528
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31272
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0599
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
Perturb_98_KD_INTS8_SRP262320	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.10281
CBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44515
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46739
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF627	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00893
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13252
PIGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60558
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
CRCGN017_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3051
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05629
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kasumi-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847568
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03476
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37144
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11486
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78508
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17448
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49845
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32396
motile cilium	GO Cellular Component Annotations 2025	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49678
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59013
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88166
NPAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47334
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.14946
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9113
CRCGN017_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1972
LIPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51741
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56131
endometrium	HPA Tissue Gene Expression Profiles	1.0	0.874116
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79315
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55722
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3873
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51517
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24847
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34241
FOXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86141
TDRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51651
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63707
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
Perturb_8923_KD_SMARCA4_SRP267639	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.5555
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6733
SSB_02_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.16993
HOXB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74055
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14646
CRCGN014_HEPG2_3H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03318
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06509
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
GJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98627
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92766
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81549
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_16004_OE_HOXA13_SRP107176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.38727
m07e	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
BZW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74832
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04395
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5465
TEX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95245
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37059
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11811
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
NT5DC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7047
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63981
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831199
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.06842
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2704
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88304
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50388
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2300_KD_BRCA1_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.33607
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60291
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9266
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36437
IL17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13817
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.84375
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996224
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20596
Cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
OTOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34533
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858041
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04076
FUS_02_155	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.85798
Acute Myeloid Leukemia_LAML_TCGA-AB-2967-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61602
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35086
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908417
HSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29377
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16784
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3307
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19845
GOLGA8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66015
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.20119
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
IFI30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17322
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26411
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	2.055
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839355
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3864_KD_INSR_SRP333146	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.81242
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4477
ZNF501	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59911
SCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93853
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31942
NRBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20808
TCEANC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31603
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57176
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39372
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82028
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3277
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
Prostate adenocarcinoma_PRAD_TCGA-VP-A87K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7184
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91645
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_311_KO_CARM1_SRP279319	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993961
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.883138
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11584
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15429
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
FGFR3_KD_GDS4454_79_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81381
F12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67726
SETD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16358
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20752
CTU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25136
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16865
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
16397242-Table1	GeneSigDB Published Gene Signatures	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08383
Universal_Human_Reference	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.41259
SNRPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68044
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63001
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51222
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957544
CRCGN012_HEPG2_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10792
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HELLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6043
SRSF4_02_12	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.32193
Acute Myeloid Leukemia_LAML_TCGA-AB-2843-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PACS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89604
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45373
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
TMEM134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30439
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876648
PRR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22388
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965128
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CSRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32036
