association	dataset	threshold value	standardized value
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0275
olfactory receptor binding	GO Molecular Function Annotations 2015	1.0	null
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55624
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85446
ZNF844	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56213
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18275
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38274
NCIH526	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54567
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ID3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27886
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38504
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065483
RASGEF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93386
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28706
intermediate stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7615
mantle zone of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10884
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49041
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835987
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
hsa-miR-125b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36624
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0252
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
gyrus rectus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838992
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01002
Perturb_1310_KO_Cntnap4_SRP387040	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.7595
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53074
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16444
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851521
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1815
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899262
PMC3470785-NIHMS377161-supplement-3.pdf-279-ZNF565_ZNF565	Rummagene Transcription Factor Associations 2026	1.0	null
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89188
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28799
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73976
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27362
acting	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-2467-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
layer 5 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39415
D-392MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.597
mantle zone of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03031
Olfactory Signaling Pathway	Reactome Pathways 2024	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34026
inaD signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.879
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61897
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8036
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25877
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFKL_OE_GDS4410_75_human_Biceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4138
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13798
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC1	DepMap CRISPR Gene Dependency	1.0	2.77771
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
DBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34007
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52393
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.912806
KNS-62	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6119
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42108
GSE210580_3_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Coleoptile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-320e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10428
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29936
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68241
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2366
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911957
ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388538
taeniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.11687
H3K36me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2021
hsa-miR-4694-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68424
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81992
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
protein localization	GO Biological Process Annotations 2023	1.0	null
TAF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67465
vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.55839
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10924
Protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1241
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42701
serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361527
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73265
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82037
mantle zone of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97896
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05528
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.535042
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15084
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5787
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04878
BDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98812
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68182
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17462
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.53097
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42857
other organism	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.801562
hsa-miR-4697-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
KAT6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50689
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	2.85814
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6222
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88905
hsa-miR-4772-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
BMI1	ChEA Transcription Factor Targets	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00987
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JE-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U251MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94507
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.05
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9183
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.680005
ventral part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03031
GSE235017_1_v_0_uba52_human	RummaGEO Gene Perturbation Signatures	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24468
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30843
Oropharyngeal anthrax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59322
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6548
Intralaminar nuclei of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03523
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08626
hsa-miR-31	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
GSE147366_3_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053769
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LNZ308	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29888
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.46296
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68729
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RPAP3/R2TP/prefoldin-like complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z2-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37955
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17739
sites	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8411-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17818
UAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58096
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979844
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07823
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95106
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Perturb_4179_KO_Tsc1_SRP279018	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06223
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835987
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.801
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84211
GSE140997_2_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979437
TAL1-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KE-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer CP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834871
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45379
KP1NL	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16166
OV90	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12406
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43785
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33538
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78043
RCOR3	ChEA Transcription Factor Targets	1.0	null
Photosystem I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05937
brain	GTEx Tissue Gene Expression Profiles	1.0	1.4321
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97774
hsa-miR-544b	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
EXTL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19395
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980918
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04583
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11538
extraorganismal space	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.801562
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068991
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leber congenital amaurosis 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
P4HB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09887
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07656
superficial stratum of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43758
UBC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31806
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64033
ELOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67408
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963971
KYSE-410	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54548
REST	ENCODE Transcription Factor Targets	1.0	null
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.722
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00714
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79533
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37236
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.363
protein insertion into membrane	GO Biological Process Annotations 2023	1.0	null
NZOV9	DepMap CRISPR Gene Dependency	1.0	8.09855
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34245
Arbuscule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
COMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02353
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82452
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.62609
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02297
Perturb_6228_KO_Mbnl1/Mbnl2_SRP142522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.35015
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9182
IZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08386
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	3.30406
ABC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9751
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7684
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.243
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.87566
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73679
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4565
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Familial glucocorticoid deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.657
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51853
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26395
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.910571
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351485
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.5588
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_20_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16189
MARK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26855
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50372
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21645
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.919
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47042
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
ZNF671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42833
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.643385
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31598
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23445
medial orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927376
NAGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80091
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04508
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
H2AK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67475
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04503
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909357
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
ERG	ChEA Transcription Factor Targets	1.0	null
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89135
hsa-miR-3944-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08983
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92197
CHD7	ENCODE Transcription Factor Targets	1.0	null
JVE015	DepMap CRISPR Gene Dependency	1.0	12.0873
glioblastoma multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.33066
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06558
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24971
ZNF236	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24345
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878209
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26793
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07339
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.933625
MITF	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3148	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Nephrogenic diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
mediodorsal nucleus of thalamus_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25047
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39723
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48326
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91819
mantle zone of PHyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44093
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22202
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31393
CADOES1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.4867
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47844
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08101
CHAGOK1	CCLE Cell Line Gene Expression Profiles	1.0	1.69943
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17229
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14839
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.37172
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Nose disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
Olfr992-Rtp1 complex	CORUM Protein Complexes	1.0	null
ICC10	DepMap CRISPR Gene Dependency	1.0	2.35642
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14903
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	2.88603
Lassa Fever Virus_8hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.7957
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68466
West syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72225
molecular_function	GO Molecular Function Annotations 2015	1.0	null
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58633
BTN3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7059
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4154
MPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17695
ZNF263	ENCODE Transcription Factor Targets	1.0	null
FUT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86372
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0668
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.939523
sensory perception of bitter taste	GO Biological Process Annotations 2025	1.0	null
superficial stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53434
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87833
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	2.50323
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05777
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyphal tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
RFX1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.45244
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41344
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68C-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCP11L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63562
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203022
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24527
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37935
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02044
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06673
mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.453355
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07893
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52387
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93826
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74168
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCI-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-218	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nasal cavity disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30552
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17592
papillae	GeneRIF Biological Term Annotations	1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19041
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58437
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23185
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
extracellular space of host	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.74417
reep	GeneRIF Biological Term Annotations	1.0	null
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63405
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54641
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988869
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66317
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MC-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04994
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51667
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4819
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68241
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	4.38525
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36793
lower basal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73763
DDX55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04935
Esophageal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cataract 31 multiple types	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.174
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875017
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16125
Plant vascular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2033
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.663555
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39998
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.03878
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1667
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77898
PNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11234
SNUC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.59632
astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.296931
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
magnocellular superficial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43758
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11007
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.61623
NCI-H1648	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59184
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5117
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25419
CDKN2AIPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45969
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929651
CAL-85-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25763
HCC2814	CCLE Cell Line Gene CNV Profiles	1.0	1.48756
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06659
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.89404
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
Mature neuron_Olfactory neuroepithelium_Human	CellMarker Gene-Cell Type Associations	1.0	null
CTF1	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-8250-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
Subparafascicular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20986
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sieve tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.892242
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60679
filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.911433
P12ICHIKAWA	CCLE Cell Line Gene Expression Profiles	1.0	1.48068
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1536
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
PCDHB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78783
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8079
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05303
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
dorsal part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44093
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13257
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7385
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68806
Xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40633
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09348
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051726
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63321
basal peduncular hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40938
diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.32373
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844083
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041386
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20034
LRRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04695
Nectary parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.435
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106758
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62621
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03052
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.01352
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ARHGEF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18841
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896923
hsa-miR-1184	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40633
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.884511
NCI-H1355	COSMIC Cell Line Gene Mutation Profiles	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.973236
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.65546
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3529
hsa-miR-423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-3657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13929
larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312957
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.95918
LS411N	Achilles Cell Line Gene Essentiality Profiles	1.0	1.36609
Receptor-transporting protein/CXXC-type zinc finger protein 11	InterPro Predicted Protein Domain Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FE-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MTIF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28026
intermediate part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08278
DPY19L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36612
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39998
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.93593
AFMID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33076
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78772
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20407
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.170888
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
protein targeting	GO Biological Process Annotations 2023	1.0	null
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TNFSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19886
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.71424
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-125a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Acute Myeloid Leukemia_LAML_TCGA-AB-2999-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36566
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37501
superficial stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02833
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925132
Pharyngeal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QO-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mesenteric lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.499615
SW48	DepMap CRISPR Gene Dependency	1.0	3.73955
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	2.28394
PEX11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.473
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A6Z2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	6.81075
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94009
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.51842
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
abnormal olfactory bulb development	MGI Mouse Phenotype Associations 2023	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28605
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01067
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.248
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51141
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS26	DepMap CRISPR Gene Dependency	1.0	2.10782
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11878
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824089
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62699
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.2674
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.69675
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923009
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
abnormal forebrain morphology	MPO Gene-Phenotype Associations	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.36602
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11588
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28791
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34245
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946658
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896898
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077803
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861324
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EPDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09955
PLB985	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00406
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63879
NB1	DepMap CRISPR Gene Dependency	1.0	4.89828
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44786
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0176
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10944
KYSE70	CCLE Cell Line Gene CNV Profiles	1.0	2.01631
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3498
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957444
LFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25751
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50108
z85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9819
NCIH716	DepMap CRISPR Gene Dependency	1.0	2.37913
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876324
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
layer 2 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04028
SNU175	CCLE Cell Line Gene Expression Profiles	1.0	2.31737
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32645
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955408
UHMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2387
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965969
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13612
NCIH441	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17711
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0264
Embryonic brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2869
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21893
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1438
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
establishment of protein localization to membrane	GO Biological Process Annotations 2023	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24933
GSE135030_8_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrial inner membrane assembly complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
mantle zone of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40636
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10884
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10963
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.700262
hsa-miR-4692	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10188
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16746
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825158
CERT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69172
MAVER1	DepMap CRISPR Gene Dependency	1.0	5.8832
MCM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3853
TP53-22127205-IMR90-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.18845
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8036
ESO51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PATU8988S	CCLE Cell Line Gene Expression Profiles	1.0	1.65506
KDM5B	ENCODE Transcription Factor Targets	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39932
Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41942
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27676
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82096
protein insertion into membrane	GO Biological Process Annotations 2015	1.0	null
SEMA6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41772
protein targeting to membrane	GO Biological Process Annotations 2025	1.0	null
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65654
membrane part	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-DX-A3UE-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401007
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3169
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CORL23	Achilles Cell Line Gene Essentiality Profiles	1.0	1.41641
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17244
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.36348
Extraorganismal space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.585
KMCH1	DepMap CRISPR Gene Dependency	1.0	2.24571
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
layer 5 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25763
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957787
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25763
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.276
CAMA1	DepMap CRISPR Gene Dependency	1.0	6.75402
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.29989
GSE176008_7_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34254
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A48U-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91478
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49507
ISTMES2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7494
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040597
hsa-miR-3913-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37238
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258547
Sensory dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.981
HUNS1	DepMap CRISPR Gene Dependency	1.0	3.07691
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.95622
BECKER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47461
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.748646
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2115
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3715
BMI1-19503595-MEFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07374
HSFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31847
superficial layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44431
Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2965-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04848
mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8222
COV318	CCLE Cell Line Gene Expression Profiles	1.0	1.56986
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61707
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_12_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54312
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01449
parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.26266
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54933
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06016
ZNF839	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53643
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1463	DepMap CRISPR Gene Dependency	1.0	5.54995
GSE115363_2_v_4_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRRC8E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01453
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03692
intermediate tier of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10966
hsa-miR-1226	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82822
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885612
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12937
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24629
STAT3	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JD-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
20203266-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
ZDHHC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40398
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52393
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85818
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37034
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37919
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259929
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057594
upper basal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03874
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960117
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869529
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61544
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68366
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48074
NCIH661	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41769
Entorhinal area, medial part, dorsal zone, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06057
SNU489	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89805
496100408_PCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33773
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0581
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17048
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15669
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.50184
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07103
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20418
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.44958
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04379
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24912
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30507
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central layers of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03219
layer 6 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05184
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.873916
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GNE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67782
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046336
goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.495701
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2029
TE10	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.44489
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28644
BRMS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37271
ZNF107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74009
mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404418
abnormal telencephalon morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16464
intermediate stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03219
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28054
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042596
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01092
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.64393
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.945546
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29815
BAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69707
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872219
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.195353
establishment of protein localization to membrane	GO Biological Process Annotations 2015	1.0	null
BT474	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08959
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26395
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20161
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.45582
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86846
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19615
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.878215
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.136831
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PRKACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91829
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1291
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01151
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22681
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7987
MAC2A	DepMap CRISPR Gene Dependency	1.0	2.72772
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.1128
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04413
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25069
protein targeting	GO Biological Process Annotations 2025	1.0	null
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.15375
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.846174
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85446
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
INO80C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.44033
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75913
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17309
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.8712
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058491
r2tp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.15518
intermediate (interpositus) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11793
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30648
BCP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22925
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03587
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57344
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.39842
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81368
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33296
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03052
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00987
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7147
GSE144500_7_v_6_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
Taeniasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
Cysticercosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80168
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48487
GB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49056
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28775
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13657
sensory perception of bitter taste	GO Biological Process Annotations 2023	1.0	null
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43982
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834913
Procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.016
KYSE-70	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.236
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.58122
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11257
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01285
abnormal brain development	MPO Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28147
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094841
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	2.24856
detection of chemical stimulus involved in sensory perception of taste	GO Biological Process Annotations 2025	1.0	null
SW948	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70426
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	1.34039
layer 4 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19972
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19759
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1867
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.1131
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083768
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420004
biological_process	GO Biological Process Annotations 2015	1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.33571
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33392
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5906
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03219
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.02689
Rhinencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
hsa-miR-4640-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Plant cuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79634
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02573
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	1.42524
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.208
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11787
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956817
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23064
mantle zone of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14605
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28044
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.22089
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23127
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043079
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05732
mantle zone of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01408
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16862
HS695T	DepMap CRISPR Gene Dependency	1.0	2.51206
BACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52407
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934532
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999133
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ribulose bisphosphate carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_14505_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.062
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875017
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.5628
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal olfactory bulb morphology	MPO Gene-Phenotype Associations	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7803
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71222
KYSE-50	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8559
liminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14347
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0107
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
Superior colliculus, motor related, intermediate gray layer, sublayer a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01303
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.53
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.44464
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139198
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
KALS1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09631
SLR24	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.16158
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03541
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05062
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
protein targeting to membrane	GO Biological Process Annotations 2023	1.0	null
Aortic arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06989
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UW228	DepMap CRISPR Gene Dependency	1.0	3.51009
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14222
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848854
CEBPB	ENCODE Transcription Factor Targets	1.0	null
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55223
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NI-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04957
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal brain morphology	MPO Gene-Phenotype Associations	1.0	null
GSE182180_1_v_2_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03405
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
rara_21299862_mcf7_lof_human__gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-4.46E-4
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24709
RPP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03051
Olfactory placode cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
INTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69022
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4245
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15876
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92684
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.219094
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31636
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
Phloem parenchyma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
hsa-miR-5047	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7208
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51015
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Thygro-r__CIC-1n_h-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.98832
KYSE30	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14005
C16orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92932
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824089
201T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88683
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.703
hsa-miR-4713-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2458
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60325
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7035
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55048
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03568
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41848
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.93684
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0607
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18275
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961923
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RTKN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87846
ERGIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18193
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4286
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9183
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.864424
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73E-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.385
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.112
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
nuclear pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.324576
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73656
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03483
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.912
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18638
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15671
lytic vacuole	LOCATE Predicted Protein Localization Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.367129
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
SCC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.874639
mantle zone of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08108
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.887628
T47D	CCLE Cell Line Gene Expression Profiles	1.0	1.99897
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
Bardet-Biedl syndrome 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.597
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11107
EZH2	ENCODE Transcription Factor Targets	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23942
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38216
Intrahepatic cholestasis of pregnancy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0536
hsa-miR-548a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07988
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2964
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844986
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4704
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8042-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0461
LRRC37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40305
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04918
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22542
Guard cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
OXLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28609
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02242
DHRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45432
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68854
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056526
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45507
PTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24898
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824089
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82507
protein localization	GO Biological Process Annotations 2025	1.0	null
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6615
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73606
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0859
rtp	GeneRIF Biological Term Annotations	1.0	null
KLF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48718
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09059
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09476
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24829
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055059
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52443
extrahaustorial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	2.74417
hsa-miR-548e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Casparian strip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.6303
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02792
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50026
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08016
OP-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Glycoproteinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
Rhinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
NCIH747	DepMap CRISPR Gene Dependency	1.0	3.03796
steps	GeneRIF Biological Term Annotations	1.0	null
SUIT2	DepMap CRISPR Gene Dependency	1.0	2.82745
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00834
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040042
hsa-miR-548f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
anterior pretectal nucleus, ventral core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7615
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00987
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28864
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INTS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73296
mediates	GeneRIF Biological Term Annotations	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9183
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052227
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8302
NCKIPSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08995
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85897
HOXD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40652
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01772
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040318
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24605
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9608
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63437
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052841
Zinc-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.30746
Photosystem I reaction center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17243
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868966
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69259
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9183
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_8_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03392
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.6701
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829209
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66015
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29508
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932316
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D423MG	DepMap CRISPR Gene Dependency	1.0	2.10096
4-aminobutyrate transaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1844
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.871555
culture supernatant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262304
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856067
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9183
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1272
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48178
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835987
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.101913
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78365
FERD3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03761
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1468
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tectal gray formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40938
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06594
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	2.13617
CISD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93094
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
ventral premammillary nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86414
CER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04528
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.79669
LP1	DepMap CRISPR Gene Dependency	1.0	2.21764
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FAAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20576
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042225
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15757
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16069
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15731
CL40	CCLE Cell Line Gene Expression Profiles	-1.0	-3.31477
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827195
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17459
Host extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.221
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54144
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
LNCaP clone FGC	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
peduncular (caudal) hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01772
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157218
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08892
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04779
VBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55819
mc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01285
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.19582
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.958244
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37965
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC18A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45393
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63666
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054309
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30726
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904607
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05937
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88288
Vomeronasal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
CAOV3	DepMap CRISPR Gene Dependency	1.0	3.40753
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98291
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
multiple	GeneRIF Biological Term Annotations	1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	2.04633
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB453	DepMap CRISPR Gene Dependency	1.0	3.78136
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51345
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33806
MMP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17215
RBBP5	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW480	CCLE Cell Line Gene Expression Profiles	1.0	1.40936
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adductor longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
HRT-18 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
detection of chemical stimulus involved in sensory perception of bitter taste	GO Biological Process Annotations 2023	1.0	null
LTF	MotifMap Predicted Transcription Factor Targets	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16029
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.42048
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1168
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8036
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17284
G401	CCLE Cell Line Gene Expression Profiles	1.0	1.46325
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27577
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00987
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.4883
cell surface	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.312224
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875212
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0147
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIN87	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02003
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stromule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
r6 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01368
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39998
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14681
Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal operculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.882035
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.6076
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040384
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9397
hsa-miR-4691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77619
Xcp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00017
Necrosis	CTD Gene-Disease Associations	1.0	1.10388
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051034
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01783
Cellular bud neck contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01092
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.3356
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
Apoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.041
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.28021
LS1034	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52987
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.846874
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4949
Olfactory glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22371
G protein-coupled receptor binding	GO Molecular Function Annotations 2025	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8875
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30878
A-Netherlands-602-2009(H1N1)_36Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.43239
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.12036
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05777
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68598
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Haustorium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.791
SALE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25489
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27796
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94657
precommissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09642
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21312
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33296
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90611
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86791
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11878
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91819
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2645
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p1Lim part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07291
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.8712
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80528
U87MG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.1795
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01063
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2557
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16233
hsa-miR-548g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.48
superficial stratum of p3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1912
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.949
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2636
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1146
SNU899	CCLE Cell Line Gene CNV Profiles	1.0	1.36376
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01286
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41535
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4566
Perturb_9048_OE_PRRX1B_SRP168742	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.77979
intermediate stratum of PHyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41538
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61906
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.84117
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61628
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96463
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34026
LDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54165
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57594
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.308
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.948503
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2968
KNS62	CCLE Cell Line Gene CNV Profiles	1.0	1.35801
abnormal nervous system development	MPO Gene-Phenotype Associations	1.0	null
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75336
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26823
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6468
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28128
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.560311
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C21orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30445
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02573
PARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56103
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8036
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06875
hsa-miR-4318	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63618
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40552
FBXO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49506
Ventral premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73763
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69865
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1624
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05777
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58504
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.750839
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
ELAVL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71096
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11189
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02174
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34206
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.91844
Myosin III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.082
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87825
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6913
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14473
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39015
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47788
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073797
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04916
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24597
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87944
mantle zone of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06734
SUMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89857
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9639
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5154
Sarcoma_SARC_TCGA-WK-A8XX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890782
testis	GeneRIF Biological Term Annotations	1.0	null
IEC-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3292
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947535
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824089
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58896
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.11079
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16444
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51853
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26729
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64798
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53076
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39617
Cervical adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.592
receptor binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_17229_KO_Tsc1_SRP096336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.48664
ASTE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57093
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12883
HCC56	DepMap CRISPR Gene Dependency	1.0	3.33266
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402523
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
hsa-miR-1244	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Mucolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61123
Prostate adenocarcinoma_PRAD_TCGA-EJ-5517-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34703
periventricular stratum of p2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14389
SMARCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37268
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
TLX1::NFIC	MotifMap Predicted Transcription Factor Targets	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.35849
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5979
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96732
Sarcoma_SARC_TCGA-PC-A5DK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37521
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26557
SJRH30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69631
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23599
TAF6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32706
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96818
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31857
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.92833
CAL120	DepMap CRISPR Gene Dependency	1.0	3.13225
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23913
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99363
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22929
SUPV3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24693
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00987
LAMA84	Achilles Cell Line Gene Essentiality Profiles	1.0	1.34866
PELI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99235
N-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18907
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
AP1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20651
SLVL	DepMap CRISPR Gene Dependency	1.0	2.98104
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.99665
hsa-miR-4257	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22851
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37417
esophagus	GTEx Tissue Gene Expression Profiles	1.0	0.866816
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16704
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912147
ABCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68223
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35596
BHK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97788
HCC1806	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51886
hsa-miR-4716-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS852T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0115
hsa-miR-3184	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16083
circumvallate	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052958
ABHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59933
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40028
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.273
HCC1187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52241
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
detection of chemical stimulus involved in sensory perception of bitter taste	GO Biological Process Annotations 2025	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12791
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32357
SMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67711
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.437
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.209
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0923
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9183
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48571
RORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44294
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74371
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7874
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
protein insertion into membrane	GO Biological Process Annotations 2025	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RNASE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52407
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361901
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
253J	CCLE Cell Line Gene Expression Profiles	1.0	1.54961
LC-1-SQ	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
Primary root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67655
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06901
HDAC6	ENCODE Transcription Factor Targets	1.0	null
abnormal olfactory bulb development	MPO Gene-Phenotype Associations	1.0	null
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042023
cysticercosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.12825
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966938
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50716
olfactory receptor binding	GO Molecular Function Annotations 2023	1.0	null
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.91309
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63402
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01186
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53671
hsa-miR-4286	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-4682	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
FAM217B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1242
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-1301	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48332
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824089
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32725
93T449	DepMap CRISPR Gene Dependency	1.0	2.74283
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16069
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33296
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1052
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29682
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6451
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65323
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118501
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94984
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.53427
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12983
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
TP63	ChEA Transcription Factor Targets	1.0	null
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063944
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79566
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071638
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10681
RDES	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36325
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.6429
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02703
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.198
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875017
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999133
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.916265
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91819
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.195353
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7774
Small intestine cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93812
KDM5A	ENCODE Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11787
hsa-miR-615-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81461
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74429
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.92628
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63269
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03219
RAB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87383
TP53	ChEA Transcription Factor Targets	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040659
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3336
hsa-miR-4251	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
LACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18274
hsa-miR-4421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
perimammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97896
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.61749
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.32786
mantle zone of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70606
hsa-miR-532-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SIMA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91349
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047788
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2373
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26684
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04133
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07671
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7888-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ENSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95037
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04581
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27582
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
RNF220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57733
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL4	DepMap CRISPR Gene Dependency	1.0	3.70329
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54183
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amnestic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.930828
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.824583
Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34565
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4887
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	2.46547
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30318
ATPase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.609
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51853
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87221
Sarcoma_SARC_TCGA-IE-A3OV-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
RELA	ENCODE Transcription Factor Targets	1.0	null
Nectary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75272
hsa-miR-511	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.64
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.84089
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48446
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24629
S-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2879
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06246
Perturb_4873_KO_EZH2_SRP095403	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.34169
Spear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9476
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70566
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63818
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95233
ING3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12815
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6523
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08867
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61593
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.885563
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18066
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Receptor-transporting protein 1	InterPro Predicted Protein Domain Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4476
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0509
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50484
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B800-850 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.831
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29026
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37806
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28923
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.24341
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
hsa-miR-4278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.392
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1314
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30831
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89261
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06901
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16709
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAGOHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26018
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39998
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25485
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0294
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27382
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.56417
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.825
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.161
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.12908
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07273
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Bam protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
Perturb_2240_KO_L2hgdh_SRP093280	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.24257
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
PAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64186
H4K91ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79402
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09162
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PCYT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25427
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88651
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40661
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00987
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80217
GSE147366_1_v_5_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49757
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862737
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919599
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17813
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17545
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47025
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63365
host	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.41586
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03385
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00793
Axon hillock	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87557
TIGAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94669
hsa-miR-2113	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26553
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0026
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Tibialis posterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81794
Posterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22369
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876324
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26281
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895436
membrane organization	GO Biological Process Annotations 2025	1.0	null
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.284
receptors	GeneRIF Biological Term Annotations	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10178
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06374
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05833
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46254
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15902
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14321
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59685
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.271
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15507
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13739
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07527
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU1040	CCLE Cell Line Gene Expression Profiles	1.0	1.51219
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35008
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88992
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40652
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00693
FOS	ENCODE Transcription Factor Targets	1.0	null
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4944
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9207
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.914314
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1624
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11216
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS944T	Achilles Cell Line Gene Essentiality Profiles	1.0	1.04388
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25175
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8938
AP4M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62051
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057679
inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.212271
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2975
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13886
CTCF	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062405
Kidney Chromophobe_KICH_TCGA-KL-8330-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
FARAGE	DepMap CRISPR Gene Dependency	1.0	2.30946
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1015
MRPL32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37707
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.17312
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51726
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4123
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62015
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075221
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918436
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01303
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40335
U178	Achilles Cell Line Gene Essentiality Profiles	1.0	2.61535
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.921311
abnormal olfactory lobe morphology	MPO Gene-Phenotype Associations	1.0	null
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40281
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097896
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.93718
TE441T	CCLE Cell Line Gene CNV Profiles	-1.0	-2.53986
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled receptor binding	GO Molecular Function Annotations 2015	1.0	null
GSE186440,GSE186443_3_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHK-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89988
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
LMNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25907
SNU-61	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.2836
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3036
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44115
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051176
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41545
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06512
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3536
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14634
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54989
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05568
layer 1 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27408
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03093
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91791
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04186
BMI1-19503595-MEFC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.66668
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV362	DepMap CRISPR Gene Dependency	1.0	4.73375
ventral part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14806
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28646
LAN2	DepMap CRISPR Gene Dependency	1.0	2.29995
short	GeneRIF Biological Term Annotations	1.0	null
translocation	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942866
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	2.40813
taste	GeneRIF Biological Term Annotations	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0381
SOX5	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33167
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16704
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03419
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28781
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17572
HS606T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55275
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14428
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6706
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67781
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81232
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55722
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04918
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53707
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927523
peduncular subparaventricular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06734
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20985
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.889097
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8818
villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288514
Perturb_4871_KO_EZH1_SRP095403	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.7715
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059974
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.848235
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888922
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.938004
SJSA1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.18815
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33583
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14765
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976937
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5501
LN319	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7899
primary motor cortex (area M1, area 4)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07726
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055061
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.951818
membrane organization	GO Biological Process Annotations 2023	1.0	null
hsa-miR-4514	TargetScan Predicted Conserved microRNA Targets	1.0	0.103424
TM7SF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11868
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174881
PMC4521181-oncsis201520x8.pdf-61-FOXE1_FOXE1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38141
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3903
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04963
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897803
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15507
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18876
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4978
WBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80491
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83617
palate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49196
496100432_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01017
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49006
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.22125
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.46834
H3C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28571
Hemolytic-Uremic Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83205
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.947808
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466111
YLPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26807
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186089
ZFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36327
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054108
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85785
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881512
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02833
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infancy electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00118
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40077
Fine root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834135
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.86557
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34026
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9007
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854253
GSE115363_2_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	3.01489
GSE147366_3_v_5_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.84089
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3409
496100503_HIP_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04633
NUP214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38092
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07656
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842756
Rhabdomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
infertility	MPO Gene-Phenotype Associations	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95027
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5965
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80104
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.57658
hsa-miR-4529-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54887
RT11284	CCLE Cell Line Gene Expression Profiles	1.0	1.70974
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37859
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10758
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.3281
FKBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59126
Kidney Chromophobe_KICH_TCGA-KL-8325-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55047
cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCIH2196	CCLE Cell Line Gene CNV Profiles	1.0	1.62852
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47018
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824089
hsa-miR-3126-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29721
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
IRF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62942
Lassa Fever Virus_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60858
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ventral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70868
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.92628
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27113
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27894
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11109
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20821
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02411
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947511
lysosome	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Gas vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.633
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39587
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056738
AR	ChEA Transcription Factor Targets	1.0	null
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89112
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42097
SAP30	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8523
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05184
Expression and translocation of olfactory receptors	Reactome Pathways 2024	1.0	null
GLYCTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77625
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074629
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30907
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46343
BXPC3	Achilles Cell Line Gene Essentiality Profiles	1.0	1.7954
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.559062
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99951
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC38	DepMap CRISPR Gene Dependency	1.0	2.11083
hsa-miR-609	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09309
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02462
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04701
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29844
Kidney Chromophobe_KICH_TCGA-KM-8443-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059986
hsa-miR-498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6239
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42193
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.873569
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19761
IDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00707
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15081
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15877
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19393
hsa-miR-580	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834913
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02214
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03052
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5026
hsa-miR-583	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26355
hsa-miR-4738-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.147
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.199389
GSE115363_2_v_0_esrrb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5749161-supp_gad.305813.117_Supplemental_Table_S2.xlsx-CLOCK_DEG_database-Supplemental_Table_S2_Differentially_expressed_genes_database_and_gene_set_intersections_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22501
detection of chemical stimulus involved in sensory perception of taste	GO Biological Process Annotations 2023	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.890785
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
R2TP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.373
Diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49275
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.17158
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27447
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.054
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190607
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833358
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63333
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2091
OELE	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.46377
PRDM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39916
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3164	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
establishment of protein localization to membrane	GO Biological Process Annotations 2025	1.0	null
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.876934
BYSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2518
Perturb_17952_KO_Shank2_SRP314506	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.66129
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.909654
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824089
PMC10679662-mmc3.xlsx-NC-D3-ZEB2-Mutant-Downregulated-Unnamed_7_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
SKMM2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.04095
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0222
TE-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.41451
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2828
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853248
Lung squamous cell carcinoma_LUSC_TCGA-33-4547-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LK2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05732
PFKL_OE_GDS4410_202_human_biceps	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Orde	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47499
infertility	MGI Mouse Phenotype Associations 2023	1.0	null
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00691
H3C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49622
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85432
SNU475	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42054
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8264-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240216
Cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
hsa-miR-4312	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0032
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.578675
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sieve cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8117
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
NB17	DepMap CRISPR Gene Dependency	1.0	2.22177
TTYH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39966
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37859
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.37343
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54056
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051822
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59355
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
binding	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9333
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47973
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36503
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19615
Intrinsic component of periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54065
malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.379626
plant-type vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
NSUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58407
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039761
IHH4	DepMap CRISPR Gene Dependency	1.0	6.4336
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2115
KMS12BM	CCLE Cell Line Gene Expression Profiles	1.0	2.65283
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
NAA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25399
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.864813
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.192
ZNF853	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47111
CDC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44935
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	12.8965
membrane	GO Cellular Component Annotations 2015	1.0	null
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06374
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_4_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
UBTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87953
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.15786
Host cellular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.28
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35814
odorant	GeneRIF Biological Term Annotations	1.0	null
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6617
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31016
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34221
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3752
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NR3C1	ChEA Transcription Factor Targets	1.0	null
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8818
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82714
phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70573
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47632
HDAC2	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.868631
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03019
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45641
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01092
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21552
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061697
COLO668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91939
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0372
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.972
GSE176008_8_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HL60	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.12995
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22851
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87833
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7909
REST	ChEA Transcription Factor Targets	1.0	null
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.69757
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5002
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056791
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	2.1566
RKO	CCLE Cell Line Gene Expression Profiles	1.0	1.80817
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7011
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91454
SREBP1-19666523-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RL952	CCLE Cell Line Gene Expression Profiles	1.0	1.57882
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84148
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26727
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15992
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
Extrahaustorial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.267
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01092
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37949
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947995
TAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5902
Gastrointestinal anthrax	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92105
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.916244
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14653
cell surface	GO Cellular Component Annotations 2015	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05921
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9183
U251	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4319	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CCDC127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96751
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21116
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74353
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98804
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42911
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53726
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32401
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FRTL-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05325
olfactory receptor binding	GO Molecular Function Annotations 2025	1.0	null
G protein-coupled receptor binding	GO Molecular Function Annotations 2023	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6813
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80365
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985981
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9385
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7156
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8646
colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.388538
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06764
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF397	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46937
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25054
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.10774
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitotic actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18732
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58259
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.948
Subiculum, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03317
SREBF1	ChEA Transcription Factor Targets	1.0	null
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56748
Aedesalbopictus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058263
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63768
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21211
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51682
NCIH2106	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50614
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01077
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.922328
lymph node	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081557
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SREBP1-19666523-LIVER-FROM-C57BL-MICE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853474
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886624
RND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02787
CHD1	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13992
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50806
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4989
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH28	CCLE Cell Line Gene Expression Profiles	1.0	1.56805
Perturb_8634_KO_Htr6_SRP223109	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.5039
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18649
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51927
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TO14	DepMap CRISPR Gene Dependency	1.0	2.16762
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
KTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91101
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59345
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34245
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10046
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.875017
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	1.76508
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51384
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.876324
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27685
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null