association	dataset	threshold value	standardized value
interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.62257
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4358
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.220604
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal sodium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7838
Fatty Liver	CTD Gene-Disease Associations	1.0	1.35444
PMC9378837-Table_3.xlsx-ESR2_upstream_regulators-2000-2021_QIAGEN_All_rights_reserved_ESR2	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01635
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956298
increased circulating aspartate transaminase level	IMPC Knockout Mouse Phenotypes	1.0	null
OUMS27	CCLE Cell Line Gene Expression Profiles	1.0	3.4081
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regions	GeneRIF Biological Term Annotations	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
mapping	GeneRIF Biological Term Annotations	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.94025
PTEN_01_303	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.19448
tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387404
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09195
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073806
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4507
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.5008
CDH4-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
HT29	CCLE Cell Line Gene CNV Profiles	1.0	1.74485
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
moroccan	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endometrial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12656
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949593
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
decreased male germ cell number	MPO Gene-Phenotype Associations	1.0	null
ESR1	ChEA Transcription Factor Targets	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Deep fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93669
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87188
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2964
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
ZNF827	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75965
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1768
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839702
Cervical mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429859
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28552
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.756156
anorchia	GeneRIF Biological Term Annotations	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02911
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
GTEX-XQ8I-0526-SM-4BOPS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82045
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.249
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16533
ZBTB22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84917
Necrosis	CTD Gene-Disease Associations	1.0	1.09471
PCDHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17975
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.45662
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09076
Ovarian cyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
AKAP17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64976
regulation of nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88678
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45415
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.68965
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.70129
bone resorption disease	GWASdb SNP-Disease Associations	1.0	0.87287
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1135
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22455
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1813
early	GeneRIF Biological Term Annotations	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825141
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49233
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.2413
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAIAP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69412
Acute Myeloid Leukemia_LAML_TCGA-AB-2842-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.418
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17533
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.706812
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63853
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.35705
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.182573
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12748
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871694
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849209
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0193
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39032
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1249
PGC-1alpha_Deficiency_GDS4904_310_mouse_Aged gastrocnemius muscle - 10 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Caput epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
A(C10/15S)INSL3	DGIdb Drug Targets 2026	1.0	1.82524
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371994
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41733
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.394
GTEX-TMMY-2226-SM-4DXTN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95351
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.144771
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24629
Fetal serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
496100570_HIP_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42612
hepatocellular	GeneRIF Biological Term Annotations	1.0	null
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29309
increased heart rate variability	MGI Mouse Phenotype Associations 2023	1.0	null
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00584
SW948	CCLE Cell Line Gene CNV Profiles	1.0	1.97224
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6003
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.687
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Smooth endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01496
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
N6-PHENYLADENOSINE	DGIdb Drug Targets 2026	1.0	0.260749
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.664775
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31525
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.740915
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.905404
PMC3921136-CIN-13-2014-021-s001.pdf-175-RUNX2_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1297
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18567
lgr8	GeneRIF Biological Term Annotations	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.36173
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275444
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3875
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11585
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283545
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.51542
positive regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95296
Internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.333
abnormal lens morphology	MGI Mouse Phenotype Associations 2023	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARS-CoV MA15_Day2-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79203
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61209
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33685
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5826
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77878
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61144
uterine benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.385936
MICALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59955
ligandmediated	GeneRIF Biological Term Annotations	1.0	null
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48143
hsa-miR-4520a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	DepMap CRISPR Gene Dependency	1.0	3.70291
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1977
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22709
all	HPO Gene-Disease Associations	1.0	null
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01455
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.162546
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
homeostasis	GeneRIF Biological Term Annotations	1.0	null
SNU175	CCLE Cell Line Gene Expression Profiles	1.0	1.69483
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.267
abnormal ligament morphology	MPO Gene-Phenotype Associations	1.0	null
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04475
RLN2	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14841
Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
absent gametes	MPO Gene-Phenotype Associations	1.0	null
abnormal male reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
increased circulating calcium level	MPO Gene-Phenotype Associations	1.0	null
PKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31307
Radiation cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.9
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898293
A(Δ10/15C)INSL3	DGIdb Drug Targets 2026	1.0	1.82524
GTEX-X4LF-1726-SM-3NMBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48314
rxfp3	GeneRIF Biological Term Annotations	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-2.43528
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852986
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61496
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27484
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29822
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03236
HS695T	DepMap CRISPR Gene Dependency	1.0	3.76088
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3417
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.865
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16979
autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.37045
signal transduction	GO Biological Process Annotations 2015	1.0	null
RCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03838
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7585-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077952
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079665
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3732
superficial stratum of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26965
CLPP_KO_GDS4791_106_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-TAL1-sequence_name_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43885
peptide binding	GO Molecular Function Annotations 2015	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46109
TE9	CCLE Cell Line Gene CNV Profiles	1.0	1.6627
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968066
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387404
abnormality of limb bone	GWASdb SNP-Phenotype Associations	1.0	0.197836
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37907
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059027
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27901
A(4-24)(B7-24)H2	DGIdb Drug Targets 2026	1.0	0.91262
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13253
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.398199
infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.844621
osteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479312
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931506
stage	GeneRIF Biological Term Annotations	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42932
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68481
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
CAL120	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46789
Perturb_13011_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.70747
endocrine	GeneRIF Biological Term Annotations	1.0	null
studies	GeneRIF Biological Term Annotations	1.0	null
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25865
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10178
hsa-miR-130b	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2423
Uninucleate trophoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28059
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
abnormal inguinal canal morphology	MPO Gene-Phenotype Associations	1.0	null
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5645
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10209
bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.590948
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
deleterious	GeneRIF Biological Term Annotations	1.0	null
failure	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.454816
increased heart rate variability	IMPC Knockout Mouse Phenotypes	1.0	null
Groin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.063
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9614
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02398
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
significant	GeneRIF Biological Term Annotations	1.0	null
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62575
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.88
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.512
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71413
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12893
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.38109
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925511
NCIH2887	DepMap CRISPR Gene Dependency	1.0	6.21002
Peptide ligand-binding receptors	Reactome Pathways 2024	1.0	null
FOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15058
abnormal circulating calcium level	MPO Gene-Phenotype Associations	1.0	null
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98969
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79029
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.917351
craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.372369
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94761
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65867
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63126
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3381
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.526
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
abnormal gland morphology	MPO Gene-Phenotype Associations	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09758
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60573
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5999
key	GeneRIF Biological Term Annotations	1.0	null
structural	GeneRIF Biological Term Annotations	1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OVMANA	CCLE Cell Line Gene Expression Profiles	1.0	1.54902
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933012
STAT3	ENCODE Transcription Factor Targets	1.0	null
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64067
External male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.288
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.6666
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51573
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7532
HAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58128
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.66472
ZBTB32	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0281
cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066229
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116587
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8231
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01454
increased circulating alkaline phosphatase level	MGI Mouse Phenotype Associations 2023	1.0	null
ONECUT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6685
ERG	ChEA Transcription Factor Targets	1.0	null
truncated	GeneRIF Biological Term Annotations	1.0	null
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.80378
developmental process	GO Biological Process Annotations 2015	1.0	null
KIF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98209
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415434
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PP-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31145
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.15088
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7056-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01616
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
affecting	GeneRIF Biological Term Annotations	1.0	null
ESR1-22446102-UTERUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22571
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89934
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885239
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.4526
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.82218
Wnt signalosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18044
RLF-(A11-B10)-ISOPEPTIDE AMIDEA26 (XA11-B10)	DGIdb Drug Targets 2026	1.0	1.82524
ZNF285	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49043
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10289
spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347408
abnormal germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1106
[125I]INSL3 (HUMAN)	DGIdb Drug Targets 2026	1.0	1.82524
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.04427
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
STYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78211
PMC11949941-DataSheet1.pdf-23-JDP2_JDP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49355
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9291
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5061
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40716
cooperativity	GeneRIF Biological Term Annotations	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12844
Olfactory tubercle, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30797
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849093
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22206
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.68464
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11386
TMEM131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17539
BT-20	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.51039
playing	GeneRIF Biological Term Annotations	1.0	null
supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.642048
positive regulation of nucleotide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PMC12328722-41467_2025_61712_MOESM3_ESM.xlsx-D9_Pathway_enrichment_results-Unnamed_6_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM184B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17871
klinefelter's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.548971
variant	GeneRIF Biological Term Annotations	1.0	null
KCNJ14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37215
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.686
g-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO Biological Process Annotations 2015	1.0	null
Peptide ligand-binding receptors	Reactome Pathways 2014	1.0	null
extracellular space	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.321201
frequent	GeneRIF Biological Term Annotations	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852442
hsa-miR-301a	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
ligands	GeneRIF Biological Term Annotations	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53526
Essential hypertension (time to event)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
abnormal hematopoietic system morphology/development	MPO Gene-Phenotype Associations	1.0	null
Mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.057
GPRC5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82693
abnormal spermatogenesis	MPO Gene-Phenotype Associations	1.0	null
temporomandibular joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242054
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26757
infertility	MPO Gene-Phenotype Associations	1.0	null
Accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.644
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6529
RELAXIN	DGIdb Drug Targets 2026	1.0	0.91262
Archenteron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
Male urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66227
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.535
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1061_KO_Esr1_SRP087718	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.65911
epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.526744
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077172
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1198
LRPPRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98526
Signal Transduction	Reactome Pathways 2014	1.0	null
negative regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55429
follicular thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192721
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83096
BARX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39229
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26708
asp181	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14454
hormone	GeneRIF Biological Term Annotations	1.0	null
testicular	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
Male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.364
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49433
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09342
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.914
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3016
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4593
abnormal male reproductive gland morphology	MPO Gene-Phenotype Associations	1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.895
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.866486
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09413
abnormal testis weight	MPO Gene-Phenotype Associations	1.0	null
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.901
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.089
primary	GeneRIF Biological Term Annotations	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57848
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0201
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glu229	GeneRIF Biological Term Annotations	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860693
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55118
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.48634
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.888
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
RLN3	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29898
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2083
previously	GeneRIF Biological Term Annotations	1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61578
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056708
inferred	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02771
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81725
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18664
POU3F2	ChEA Transcription Factor Targets	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027965
hsa-miR-152	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.067
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853256
female reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.352291
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857065
responsible	GeneRIF Biological Term Annotations	1.0	null
ZNF608	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99953
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08832
PMC10248509-Data_Sheet_5.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Freemartinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
lipoprotein	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.855891
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
normally	GeneRIF Biological Term Annotations	1.0	null
male infertility	IMPC Knockout Mouse Phenotypes	1.0	null
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7898
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87758
Cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72281
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68862
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NT2/D1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08306
UWB1_289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Thyroid epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.73237
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053584
GTEX-T8EM-1126-SM-3DB7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4764
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849438
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
Medullary thyroid carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
CLPP_KO_GSE40207_379_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924086
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50743
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09848
HMC18	CCLE Cell Line Gene CNV Profiles	1.0	1.43676
PMC7858073__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
GDM1	CCLE Cell Line Gene Expression Profiles	1.0	1.75251
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866794
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068985
Perturb_11924_KO_JMJD3_SRP110517	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831371
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18767
FTC-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913882
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5765
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Perturb_11941_KD_SMARCD1_ERP132006	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.04901
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
sublayer 6b of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03548
Leydig cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
CORL279	DepMap CRISPR Gene Dependency	1.0	2.4158
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37177
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6748
G protein-coupled receptor activity	GO Molecular Function Annotations 2025	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30172
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22584
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NOMO1	DepMap CRISPR Gene Dependency	1.0	2.10246
SNCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40024
G alpha (s) signalling events	Reactome Pathways 2014	1.0	null
lateral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59472
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66717
testes	GeneRIF Biological Term Annotations	1.0	null
abnormal erythrocyte cell number	MPO Gene-Phenotype Associations	1.0	null
hydrocele	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.783116
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3372
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17172
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
positive regulation of camp biosynthetic process	GO Biological Process Annotations 2015	1.0	null
essential	GeneRIF Biological Term Annotations	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.979578
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66682
GTEX-S4Q7-1126-SM-4AD6R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833967
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6154
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04006
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.945
MA-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.18083
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1486
Cryptorchidism	HuGE Navigator Gene-Phenotype Associations	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04122
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7128
EIF2AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80688
membrane	GO Cellular Component Annotations 2015	1.0	null
Germinal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
MTERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07512
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39141
Microtome section	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7627
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33559
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2024	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00419
arrest of spermatogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28645
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08469
reproductive process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057431
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45684
Thyroid Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Blastopore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
site	GeneRIF Biological Term Annotations	1.0	null
GTEX-WEY5-0526-SM-3GIKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65517
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56701
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	1.43871
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11644
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68454
ocular	GeneRIF Biological Term Annotations	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6785
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28421
descent	GeneRIF Biological Term Annotations	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4298
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042645
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74889
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.34233
PRKAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18095
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39689
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584422
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9408
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1481
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
COMPOUND 6641	DGIdb Drug Targets 2026	1.0	1.82524
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
oocyte maturation	GO Biological Process Annotations 2015	1.0	null
G alpha (s) signalling events	Reactome Pathways 2024	1.0	null
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4643
actions	GeneRIF Biological Term Annotations	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879528
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14326
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6777-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20609
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865069
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
HS766T	DepMap CRISPR Gene Dependency	1.0	4.38148
abnormal lens morphology	IMPC Knockout Mouse Phenotypes	1.0	null
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03041
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02513
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978565
H2AJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95364
male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.483224
[<sup>33</sup>P]H2 relaxin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.916981
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_17685_KO_Pgr_SRP365149	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.13893
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968196
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
PMC7432388__F2	PFOCR Pathway Figure Associations 2023	1.0	null
plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.398199
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14003
INSL3 B-chain analogue	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
PMC3102637-1471-2105-12-99-S2.XLSX-11_sigpathways_in_AA_P_0_001-Unnamed_33_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ftc-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.509027
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4267
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
apparent	GeneRIF Biological Term Annotations	1.0	null
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046543
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
CTCF	ENCODE Transcription Factor Targets	1.0	null
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60298
abnormal skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
thyroid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117505
CNOT3	ChEA Transcription Factor Targets	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3016
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
HUNS1	CCLE Cell Line Gene Expression Profiles	1.0	1.94814
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19968
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3024
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MUTZ5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45826
HNF4alpha_DEPLETION_GDS4798_91_human_HepG2 hepatocellular carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Ureteric bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
PMC10973470-41698_2024_570_MOESM1_ESM.pdf-353-NR2F1_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00135
CYCLOPENTYLADENOSINE	DGIdb Drug Targets 2026	1.0	0.260749
APOBEC3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37142
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33221
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30597
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10163
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
Testicular sex cord-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
increased circulating alkaline phosphatase level	IMPC Knockout Mouse Phenotypes	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5025
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
insl3rxfp2	GeneRIF Biological Term Annotations	1.0	null
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129026
renal hypoplasia/aplasia	HPO Gene-Disease Associations	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5981
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92643
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.972837
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916594
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
missense	GeneRIF Biological Term Annotations	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36533
Sex cord-gonadal stromal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.483986
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8653
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42043
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
correct	GeneRIF Biological Term Annotations	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CLTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63012
uterus	GTEx Tissue Gene Expression Profiles	1.0	1.50988
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6343
leucinerich	GeneRIF Biological Term Annotations	1.0	null
scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.967657
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01044
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9432
PMC9378837-Table_3.xlsx-ESR1_upstream_regulators-2000-2021_QIAGEN_All_rights_reserved_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2826-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25334
GTEX-OHPK-2326-SM-3MJH2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44359
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88926
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.775998
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11802
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24054
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.943
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0269
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
NOMO1	CCLE Cell Line Gene Expression Profiles	1.0	2.16606
domains	GeneRIF Biological Term Annotations	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.64536
COLO668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6511
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
KMS11	CCLE Cell Line Gene Expression Profiles	1.0	1.91974
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.415773
hsa-miR-3659	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
trophoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305722
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0181
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GD-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
PMC6425874__F3	PFOCR Pathway Figure Associations 2023	1.0	null
HNF4A_KD_GSE29084_694_human_HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30462
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38345
urogenital ridge	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.731442
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
inhibitor	GeneRIF Biological Term Annotations	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.24101
Subrhabdomeral cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75062
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.638
CLPP_KO_GDS4791_539_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CEBPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07274
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932095
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9087
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8046
ZNF620	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93679
SUCLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81079
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2402
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Corneal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
COLO205	CCLE Cell Line Gene CNV Profiles	1.0	2.07214
GTEX-WFON-2226-SM-3TW8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36095
Myometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
GTEX-S4UY-1326-SM-4AD4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.302
striated muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584422
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30685
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891846
AURKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11006
TRIM28	ChEA Transcription Factor Targets	1.0	null
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11482
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69742
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6495
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.9253
RUNX2	ChEA Transcription Factor Targets	1.0	null
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51917
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054844
PMC3247287__F8	PFOCR Pathway Figure Associations 2023	1.0	null
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09003
identify	GeneRIF Biological Term Annotations	1.0	null
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
abnormal circulating protein level	MPO Gene-Phenotype Associations	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Chorionic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
AKAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7566
Lung adenocarcinoma_LUAD_TCGA-50-5933-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3sh_DEGs-DEGs_in_HeLa_IER3sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
decreased germ cell number	MPO Gene-Phenotype Associations	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11423
Oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
RLN1	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.910093
classa	GeneRIF Biological Term Annotations	1.0	null
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09259
abnormality of limbs	GWASdb SNP-Phenotype Associations	1.0	0.154136
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105992
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7453
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61314
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40247
theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379123
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99819
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2369
abnormal gubernaculum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40884
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
cognate	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	1.0	4.73697
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLFORSIN	DGIdb Drug Targets 2026	1.0	0.260749
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.628
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13419
GTEX-R55D-0326-SM-48FES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36523
BT20	CCLE Cell Line Gene CNV Profiles	1.0	1.91179
biological regulation	GO Biological Process Annotations 2015	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.883
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159024
Relaxin receptor	InterPro Predicted Protein Domain Annotations	1.0	null
link	GeneRIF Biological Term Annotations	1.0	null
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3158
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60652
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11883
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20512
Perturb_755_KD_ZFR_SRP107875	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.30738
Endometrial stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
RELAXIN-3	DGIdb Drug Targets 2026	1.0	0.45631
lowdensity	GeneRIF Biological Term Annotations	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
hsa-miR-548an	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
small testis	IMPC Knockout Mouse Phenotypes	1.0	null
developmental maturation	GO Biological Process Annotations 2015	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
GSE120336_1_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
clinical	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.408292
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8517
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6177
RLN2	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TUBB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36538
Tube foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30347
abnormal gametogenesis	MPO Gene-Phenotype Associations	1.0	null
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72505
small intestine	GTEx Tissue Gene Expression Profiles	-1.0	-0.827475
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22563
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A(10-24)INSL3	DGIdb Drug Targets 2026	1.0	1.82524
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881773
GTEX-S3XE-1626-SM-3K2AJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58151
cryptorchidism	OMIM Gene-Disease Associations	1.0	null
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01387
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
hsa-miR-4422	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
abnormal internal male genitalia morphology	MPO Gene-Phenotype Associations	1.0	null
follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.568424
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
LRP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44991
Perturb_11937_KD_SMARCD1_ERP132117	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.4953
EAPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71931
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828047
physiological	GeneRIF Biological Term Annotations	1.0	null
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2871
lack	GeneRIF Biological Term Annotations	1.0	null
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99301
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3246
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66525
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23898
EB1	CCLE Cell Line Gene Expression Profiles	1.0	1.44477
selectivity	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3940-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
positive regulation of cyclic nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
G protein-coupled peptide receptor activity	GO Molecular Function Annotations 2025	1.0	null
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27519
affinity	GeneRIF Biological Term Annotations	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057932
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77937
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40813
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
increased circulating sodium level	MPO Gene-Phenotype Associations	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9324
PMC7858073__F5	PFOCR Pathway Figure Associations 2024	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03703
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99647
abnormality of the femoral neck	GWASdb SNP-Phenotype Associations	1.0	0.766212
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06136
CEBPD-23245923-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24144
classical	GeneRIF Biological Term Annotations	1.0	null
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864341
NEUROG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85637
Fibroid Tumor	DisGeNET Gene-Disease Associations	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853256
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18125
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12421
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
SARS-CoV MA15_Day7-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.2143
Lung adenocarcinoma_LUAD_TCGA-62-8397-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hormone binding	GO Molecular Function Annotations 2015	1.0	null
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68669
used	GeneRIF Biological Term Annotations	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9019
NCIH1755	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63951
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
cryptorchism	MGI Mouse Phenotype Associations 2023	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82708
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.191
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990402
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16338
Lung adenocarcinoma_LUAD_TCGA-91-8496-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seminal vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366007
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAPGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04176
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922126
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922928
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00833
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.644153
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
KO52	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G protein-coupled receptor homodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9118
RNASE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47218
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
neuroactive ligand receptor interaction	KEGG Pathways	1.0	null
seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345188
Glycated hemoglobin levels in type 1 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75242
CREM	ChEA Transcription Factor Targets	1.0	null
urinary bladder obstruction	IMPC Knockout Mouse Phenotypes	1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6470-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cryptorchidism	HPO Gene-Disease Associations	1.0	null
relaxin2	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12209
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28043
LS513	CCLE Cell Line Gene CNV Profiles	1.0	1.52849
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955337
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950035
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14699
gene2	GeneRIF Biological Term Annotations	1.0	null
Filopodium membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.867
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15719
PMC2013861__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10001
camp	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52054
NECA	DGIdb Drug Targets 2026	1.0	0.228155
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27036
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75879
CSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41016
PMC2013861__F4	PFOCR Pathway Figure Associations 2023	1.0	null
increased circulating alkaline phosphatase level	MPO Gene-Phenotype Associations	1.0	null
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
bone remodeling disease	GWASdb SNP-Disease Associations	1.0	0.39874
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48143
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27945
OCIAML2	CCLE Cell Line Gene Expression Profiles	1.0	1.92785
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5444
only	GeneRIF Biological Term Annotations	1.0	null
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
developmental	GAD High Level Gene-Disease Associations	1.0	0.303208
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062571
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85191
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049321
positive regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68296
NKX6-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02165
mechanistic	GeneRIF Biological Term Annotations	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80233
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84357
UCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92284
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62878
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79176
described	GeneRIF Biological Term Annotations	1.0	null
insulin	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39035
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873396
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
abnormality of lower limb bone	GWASdb SNP-Phenotype Associations	1.0	0.394942
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.941
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.985
Holocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30155
Leucine-rich repeat-containing N-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1105
Laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19707
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825141
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.6536
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06609
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32989
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44492
X-organ-sinus-gland complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
uterine fibroid	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.387794
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3474
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73878
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26417
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.916139
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06365
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.937198
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2958
NCIH1975	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74369
peptide hormone binding	GO Molecular Function Annotations 2015	1.0	null
osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338914
KNS81	DepMap CRISPR Gene Dependency	1.0	2.08233
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	3.33267
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.33554
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6331
Amniotic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.545648
abnormal optic disk morphology	IMPC Knockout Mouse Phenotypes	1.0	null
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36424
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26753
Brain_CT2_Amex 406	HuBMAP ASCT+B Annotations	1.0	null
Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138673
NANOLUC-INSL3	DGIdb Drug Targets 2026	1.0	1.82524
abnormal blood cell morphology/development	MPO Gene-Phenotype Associations	1.0	null
alterations	GeneRIF Biological Term Annotations	1.0	null
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.91955
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7743
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15484
osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277549
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.48294
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872872
Testicular Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
RAI14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88474
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7327
hydrocephalus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.227988
PROX1_01_06	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.97292
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861627
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830086
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
renal agenesis	HPO Gene-Disease Associations	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14326
Retractile Testis	DisGeNET Gene-Disease Associations	1.0	null
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21016
oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.513802
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.594
abnormality of the femoral neck or head region	GWASdb SNP-Phenotype Associations	1.0	0.394942
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40075
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
LS411N	DepMap CRISPR Gene Dependency	1.0	10.2145
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42201
negative regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17559
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952939
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944549
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53711
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46151
TRIOBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37965
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00786
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056884
relaxinlike	GeneRIF Biological Term Annotations	1.0	null
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96735
molecular	GeneRIF Biological Term Annotations	1.0	null
Anaplasia	DisGeNET Gene-Disease Associations	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.760647
NCIH292	CCLE Cell Line Gene Expression Profiles	1.0	1.34919
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
related	GeneRIF Biological Term Annotations	1.0	null
Carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90137
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
regulation of cyclic nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8268
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18072
Antler	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
BAG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81439
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99486
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cryptorchidism	GeneRIF Biological Term Annotations	1.0	null
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4742
one	GeneRIF Biological Term Annotations	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848255
patient	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08265
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79733
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05063
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30423
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
Bladder exstrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3428-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IS-A3K8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.27334
peptides	GeneRIF Biological Term Annotations	1.0	null
theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415053
Signaling by GPCR	Reactome Pathways 2024	1.0	null
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.65455
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344449
increased erythrocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892484
further	GeneRIF Biological Term Annotations	1.0	null
decreased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
Female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.315
invasiveness	GeneRIF Biological Term Annotations	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09585
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07166
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63683
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.69947
CALU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57364
abnormal mineral level	MPO Gene-Phenotype Associations	1.0	null
Uterine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
abnormal behavior	MGI Mouse Phenotype Associations 2023	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01616
NCIH1836	DepMap CRISPR Gene Dependency	1.0	2.5152
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
abnormal gubernaculum morphology	MPO Gene-Phenotype Associations	1.0	null
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61151
secondary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.178171
abnormal male germ cell morphology	MPO Gene-Phenotype Associations	1.0	null
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51202
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0183
SMSCTR	DepMap CRISPR Gene Dependency	1.0	4.79075
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32753
MEL270	DepMap CRISPR Gene Dependency	1.0	2.36899
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2579
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.915123
Posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045615
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44099
GTEX-WY7C-2726-SM-3NB3P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00175
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2891
hsa-miR-338-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99011
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.536
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.30626
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.931781
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29926
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882223
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052108
Inguinal hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.952
provides	GeneRIF Biological Term Annotations	1.0	null
CCDC28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14572
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17117
higher	GeneRIF Biological Term Annotations	1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094176
MON	DepMap CRISPR Gene Dependency	1.0	7.40965
Hypospadias	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.439
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02398
tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183394
Mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.632
Uterine endometrial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27456
Myometrial relaxation and contraction pathways	WikiPathways Pathways 2024	1.0	null
Seminiferous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
seems	GeneRIF Biological Term Annotations	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055429
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
Detrusor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18998
Hydrocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3095
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13561
(des 1-8) A-chain INSL3 analogue	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0937
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UIMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63409
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.253
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.628
AGXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47511
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73357
Relaxin receptors	Reactome Pathways 2014	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.31925
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927399
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.40925
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.113687
gsv	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00286
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10835
all	GWASdb SNP-Phenotype Associations	1.0	0.030942
spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159642
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
Perturb_14161_KD_BZW1/BZW2_SRP316321	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.6515
positive regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2166
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5379
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.77075
Diabetic Neuropathy_Sciatic Nerve_GSE11343	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.27151
biological_process	GO Biological Process Annotations 2015	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.701
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11647
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.048
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902828
Testicular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
facilitate	GeneRIF Biological Term Annotations	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24205
NFYA-21822215-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3848
abnormal hemoglobin content	MPO Gene-Phenotype Associations	1.0	null
parents	GeneRIF Biological Term Annotations	1.0	null
effect	GeneRIF Biological Term Annotations	1.0	null
basis	GeneRIF Biological Term Annotations	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3038
Bilateral Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95686
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841299
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Decidua	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.118
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09826
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	1.45601
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.518
abnormal reproductive system morphology	MPO Gene-Phenotype Associations	1.0	null
NSUN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49516
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05655
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41537
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
increased hemoglobin content	MPO Gene-Phenotype Associations	1.0	null
CDCA7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61215
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
preosteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.146769
COLO680N	DepMap CRISPR Gene Dependency	1.0	2.15193
increased circulating sodium level	MGI Mouse Phenotype Associations 2023	1.0	null
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13502
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31648
Malignant Testicular Germ Cell Tumor	DisGeNET Gene-Disease Associations	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.550106
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1613
consequence	GeneRIF Biological Term Annotations	1.0	null
Ovarian cumulus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
TFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64463
shows	GeneRIF Biological Term Annotations	1.0	null
Mesonephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
abnormal spermatogenesis	MGI Mouse Phenotype Associations 2023	1.0	null
hsa-miR-3666	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16547
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02154
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.880733
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49178
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pleopod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.71471
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
THBS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80637
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JVE015	DepMap CRISPR Gene Dependency	1.0	2.19954
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC11625982-AJH-100-10-s001.pdf-9-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43918
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3653
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
Bladder exstrophy-epispadias-cloacal exstrophy complex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8341
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21306
hsa-miR-196b	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
positive regulation of cyclic nucleotide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042423
Sc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
[<sup>125</sup>I]INSL3 (human)	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57898
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8132
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040417
PMC6202145__F1	PFOCR Pathway Figure Associations 2023	1.0	null
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085568
TAMRLX	DGIdb Drug Targets 2026	1.0	0.91262
AMIGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07751
MOG-G-CCM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Testicular Leydig cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
BPTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14764
testis	GeneRIF Biological Term Annotations	1.0	null
hematopoietic system phenotype	MPO Gene-Phenotype Associations	1.0	null
HT144	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51204
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047364
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.724863
Immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.523
Sarcoma_SARC_TCGA-DX-A2J1-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERF-GC-1B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.57
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal testis morphology	MPO Gene-Phenotype Associations	1.0	null
external male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648938
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71905
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26665
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.648
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05201
Kallmann syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
spliced	GeneRIF Biological Term Annotations	1.0	null
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00359
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05138
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-148b	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
Inguinal canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.489
varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240148
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052299
PMC10248509-Data_Sheet_6.CSV--GSE58294_DE-genes_AND_GSE66724_DE-Genes_NOT_Autophagy_NOT_GSE22255_DE-Genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
HCE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
CEBPD-23245923-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915949
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5393
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99562
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
several	GeneRIF Biological Term Annotations	1.0	null
Testicular somatic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841507
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10492
PA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03733
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-454	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
Bladder wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9245
46,XY sex reversal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Striated muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75439
Perturb_14493_KO_Cnot4_SRP285155	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.94567
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13455
NCI-H748	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.05312
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965132
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88768
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6626
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14346
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38638
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.64
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39208
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Blastema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.9208
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9823
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97635
secondary	GeneRIF Biological Term Annotations	1.0	null
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.025
INSL3 B-CHAIN ANALOGUE	DGIdb Drug Targets 2026	1.0	1.82524
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45171
conjunctiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350743
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039935
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.70509
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
abnormal enzyme/ coenzyme level	MPO Gene-Phenotype Associations	1.0	null
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10419
2-CHLOROADENOSINE	DGIdb Drug Targets 2026	1.0	0.165931
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.41739
GTEX-S341-0826-SM-4AD73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65171
PMC8263891__F6	PFOCR Pathway Figure Associations 2024	1.0	null
rxfp1	GeneRIF Biological Term Annotations	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37665
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00223
Endometrial glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Antennal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49947
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50363
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
CLPP_KO_GDS4791_375_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38643
Ooplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
provide	GeneRIF Biological Term Annotations	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cryptorchidism	GAD Gene-Disease Associations	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.177
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21277
CAOV3	DepMap CRISPR Gene Dependency	1.0	2.51771
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.272997
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.826
GTEX-WH7G-2226-SM-3NMBN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12418
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02623
great saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.751645
HCC78	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84925
CDK19_knockdown_162_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.85585
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-SNU-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24225
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8164
Granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CEBPA-26348894-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97056
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93783
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28493
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29104
increased hematopoietic cell number	MPO Gene-Phenotype Associations	1.0	null
semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171387
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
increased erythrocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
negative regulation of cell death	GO Biological Process Annotations 2015	1.0	null
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48875
potent	GeneRIF Biological Term Annotations	1.0	null
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34021
GTEX-SE5C-0926-SM-4BRUF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42493
Gynecomastia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80278
LENG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4806
Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829878
adenylate cyclase-inhibiting g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
carriers	GeneRIF Biological Term Annotations	1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59114
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
Complete androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059685
hsa-miR-4295	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
regulation of camp metabolic process	GO Biological Process Annotations 2015	1.0	null
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621428
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54051
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49712
fold	GeneRIF Biological Term Annotations	1.0	null
gonad development	GO Biological Process Annotations 2015	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.024954
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914196
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.31593
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896048
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07214
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.012
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7649-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92305
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78275
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
ZNF398	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13524
Nipple	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6641
Persistent Mullerian duct syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.931
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5791
RAB3GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58578
abnormal optic disk morphology	MGI Mouse Phenotype Associations 2023	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063703
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.628
abnormal erythrocyte morphology	MPO Gene-Phenotype Associations	1.0	null
arrest of spermatogenesis	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia innominata/basal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01041
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.37208
GPCR ligand binding	Reactome Pathways 2024	1.0	null
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968119
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESS1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60281
SEMK2	DepMap CRISPR Gene Dependency	1.0	2.3236
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	Reactome Pathways 2014	1.0	null
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.607818
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6282
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.666
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909059
azoospermia	MPO Gene-Phenotype Associations	1.0	null
el2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
had	GeneRIF Biological Term Annotations	1.0	null
Ventilator-associated lung injury_Lung Tissue_GSE2411	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.65367
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079663
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
include	GeneRIF Biological Term Annotations	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.597181
icSARA deltaORF6_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.39791
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22206
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.43617
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5082
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.910946
ldla	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.32363
PMC6425874__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Meniscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72127
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180822
abnormal sex determination	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-3130-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2214
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24361
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07408
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837117
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.97886
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99647
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10914
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.148365
insl3lgr8	GeneRIF Biological Term Annotations	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66677
manner	GeneRIF Biological Term Annotations	1.0	null
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2834
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870131
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6104
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4654
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1749
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090637
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09012
ADNP-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08376
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056374
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.852
ZNF530	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55311
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31656
granulosa cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307528
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88678
analogs	GeneRIF Biological Term Annotations	1.0	null
extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.42082
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.79768
increased pulmonary respiratory rate	MGI Mouse Phenotype Associations 2023	1.0	null
Renal hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95382
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23225
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.16527
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epididymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.99642
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
necessary	GeneRIF Biological Term Annotations	1.0	null
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070254
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.41619
Lung adenocarcinoma_LUAD_TCGA-38-4628-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Feather barbules	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61075
CUX1	ChEA Transcription Factor Targets	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17661
present	GeneRIF Biological Term Annotations	1.0	null
various	GeneRIF Biological Term Annotations	1.0	null
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	1.49227
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.182
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0338
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
RBBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5126
valb19	GeneRIF Biological Term Annotations	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407832
CEBPD	ChEA Transcription Factor Targets	1.0	null
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6086
argb20	GeneRIF Biological Term Annotations	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5882
time	GeneRIF Biological Term Annotations	1.0	null
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.385822
PKBalpha_KO_GDS1784_196_mouse_Embryonic fibroblasts (MEFs) - 24h	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15958
lgr7	GeneRIF Biological Term Annotations	1.0	null
module	GeneRIF Biological Term Annotations	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6157
MICU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81631
Relaxin signaling pathway	KEGG Pathways 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31648
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048463
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
htr-8/svneo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.73803
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.335
Interstitial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.563
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SLC27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8402
CALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19596
Male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.374
Testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.547
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
INSL3	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08077
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30471
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.82134
increased circulating aspartate transaminase level	MGI Mouse Phenotype Associations 2023	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.628
SK-OV-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9138
PRKAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64943
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18717
scrotum	GeneRIF Biological Term Annotations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33015
INSL3	DGIdb Drug Targets 2026	1.0	0.91262
increased hematocrit	MGI Mouse Phenotype Associations 2023	1.0	null
PER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74954
Leucine-rich repeat, typical subtype	InterPro Predicted Protein Domain Annotations	1.0	null
Theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.043
OCUM1	CCLE Cell Line Gene CNV Profiles	1.0	1.37452
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942764
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24541
GTEX-S95S-1326-SM-2XCDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997346
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
regulation of nucleotide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22288
positive regulation of nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
Arthropathy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.525
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.61615
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97234
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.08142
Germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864289
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11133
amide binding	GO Molecular Function Annotations 2015	1.0	null
P31FUJ	CCLE Cell Line Gene Expression Profiles	1.0	2.16226
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68564
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14003
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2369
PLXND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50865
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12903
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.201
GSE116299_0_v_5_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A1KZ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916052
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3362-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54633
CXCR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75403
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03838
TE-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
showed	GeneRIF Biological Term Annotations	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050706
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0103
GPCR ligand binding	Reactome Pathways 2014	1.0	null
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78136
sex differentiation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.140905
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A(9-26)INSL3	DGIdb Drug Targets 2026	1.0	1.82524
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35424
Urogenital ridge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.688
C-Cell Hyperplasia Of Thyroid	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45047
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26656
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12483
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.217511
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02472
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
achain	GeneRIF Biological Term Annotations	1.0	null
negative	GeneRIF Biological Term Annotations	1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28862
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3949
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33622
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.84978
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0167
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30363
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01416
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Vaginal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
FOXO3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10733
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36164
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7243
hsa-miR-4530	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.849438
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982178
KP-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298883
Peritubular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47738
LN428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88999
CTXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51411
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042916
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.997825
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.8591
Zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12695
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415814
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7851
Carcinoma, Hepatocellular_Hepatic Tissue_GSE2127	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.58131
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63436
PCI6A	DepMap CRISPR Gene Dependency	1.0	2.02532
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9433
HNF4A_KD_GDS4798_550_human_HepG2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02474
increased circulating lipase level	IMPC Knockout Mouse Phenotypes	1.0	null
Hoof	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77599
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13726
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.40025
Cyclic AMP	HMDB Metabolites of Enzymes	1.0	null
Intrinsic component of the cytoplasmic side of the plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
activities	GeneRIF Biological Term Annotations	1.0	null
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93697
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373118
Pulse pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.42218
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.950417
SW1463	CCLE Cell Line Gene CNV Profiles	1.0	1.42009
hisb12	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
MLLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68751
male gonad development	GO Biological Process Annotations 2015	1.0	null
first	GeneRIF Biological Term Annotations	1.0	null
Glans penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0633
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
PMC3247287__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
positive regulation of purine nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824375
OVCAR-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ABCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07038
TOV21G	CCLE Cell Line Gene Expression Profiles	-1.0	-2.16532
gubernaculum testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06118
increased circulating calcium level	IMPC Knockout Mouse Phenotypes	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.5015
Relaxin receptors	Reactome Pathways 2024	1.0	null
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
small testis	MPO Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
prolonged QT interval	IMPC Knockout Mouse Phenotypes	1.0	null
C14orf119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48189
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21003
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.897635
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08469
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997139
Penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11135
20460173-ImmPortCytokineReceptors	GeneSigDB Published Gene Signatures	1.0	null
protein-hormone receptor activity	GO Molecular Function Annotations 2015	1.0	null
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32478
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827337
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.01928
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47364
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91069
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
icSARS CoV_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.1732
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25457
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37062
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5799
SW1116	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
decreased testis weight	MPO Gene-Phenotype Associations	1.0	null
varicose	GeneRIF Biological Term Annotations	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.52113
unable	GeneRIF Biological Term Annotations	1.0	null
MDAMB453	DepMap CRISPR Gene Dependency	1.0	2.2672
Medication use (diuretics)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
complete	GeneRIF Biological Term Annotations	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2216
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.875
cryptochidism	GAD Gene-Disease Associations	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57848
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31063
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3504
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0967
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33066
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
allele	GeneRIF Biological Term Annotations	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27471
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0421
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.718039
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905356
MAP3K12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62414
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8994
v39g	GeneRIF Biological Term Annotations	1.0	null
adenylate cyclase-activating g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
hsa-miR-196a	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.108658
PMC6097700-pgen.1007515.s008.xlsx-S2_Table-S2_Table_SATB2_Cort_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927695
COA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03838
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GS-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREBZF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65516
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94624
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6127
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior olfactory area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2712
reported	GeneRIF Biological Term Annotations	1.0	null
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21311
interactions	GeneRIF Biological Term Annotations	1.0	null
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21387
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.4551
Sarcoma_SARC_TCGA-DX-A8BH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34371
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80768
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02394
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21837
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31249
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925891
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
surface	GeneRIF Biological Term Annotations	1.0	null
similarities	GeneRIF Biological Term Annotations	1.0	null
abnormal circulating lipase level	MPO Gene-Phenotype Associations	1.0	null
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.384
OE33	CCLE Cell Line Gene CNV Profiles	1.0	2.08232
increased circulating sodium level	IMPC Knockout Mouse Phenotypes	1.0	null
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
into	GeneRIF Biological Term Annotations	1.0	null
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.069
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.767269
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060952
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899265
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28519
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31735
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1111
Great saphenous vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
ZNF836	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66064
METTL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52042
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2037
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lumbar spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
Leucine-rich repeat	InterPro Predicted Protein Domain Annotations	1.0	null
joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151172
Signaling by GPCR	Reactome Pathways 2014	1.0	null
dimer	GeneRIF Biological Term Annotations	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9006
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19558
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35594
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
T173	CCLE Cell Line Gene Expression Profiles	1.0	1.45359
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.06284
Perturb_745_KD_LIMK1_SRP262340	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.22495
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
differences	GeneRIF Biological Term Annotations	1.0	null
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.228764
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28904
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12717
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO Biological Process Annotations 2025	1.0	null
regulation of purine nucleotide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
RTKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15073
ETFRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8002
Weight Loss	CTD Gene-Disease Associations	1.0	1.03084
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased monocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43973
abnormal gametes	MPO Gene-Phenotype Associations	1.0	null
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30649
Cryptorchidism	CTD Gene-Disease Associations	1.0	2.88009
signal	GeneRIF Biological Term Annotations	1.0	null
positive regulation of camp metabolic process	GO Biological Process Annotations 2015	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4266
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.480945
Fibrosis	CTD Gene-Disease Associations	1.0	1.07696
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488276
reproductive structure development	GO Biological Process Annotations 2015	1.0	null
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42947
any	GeneRIF Biological Term Annotations	1.0	null
mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190601
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85102
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63935
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63186
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887515
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12252
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28367
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal erythropoiesis	MPO Gene-Phenotype Associations	1.0	null
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11552
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.081
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.57779
NR2F2_01_07	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.35375
Bark	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
organ development	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2106	CCLE Cell Line Gene Expression Profiles	-1.0	-3.70054
PRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66904
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91886
SNU475	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02343
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20645
testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.842573
TC71	CCLE Cell Line Gene Expression Profiles	1.0	1.57435
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.95845
ATL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41825
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.789
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2712
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064125
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48926
POU5F1	ChEA Transcription Factor Targets	1.0	null
increased hematocrit	MPO Gene-Phenotype Associations	1.0	null
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11113
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84883
SNU1076	CCLE Cell Line Gene Expression Profiles	1.0	1.37286
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.164
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.504
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.7798
SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.52493
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841261
CLPP_KO_GSE40207_394_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81931
myometrial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276145
FBXO17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28256
azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.20658
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59114
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56748
Inhibin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.71
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40498
predicted	GeneRIF Biological Term Annotations	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1688
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40974
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41601
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02378
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.86154
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELAXIN-1	DGIdb Drug Targets 2026	1.0	0.91262
cell maturation	GO Biological Process Annotations 2015	1.0	null
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20324
process	GeneRIF Biological Term Annotations	1.0	null
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17982
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2358
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14772
Spontaneous preterm birth without premature rupture of membranes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047852
abnormal ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20776
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.411039
bchain	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6812-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72687
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71751
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38331
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15484
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259254
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15727
Acute Myeloid Leukemia_LAML_TCGA-AB-2965-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939664
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4742
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96218
corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253578
bilateral cryptorchism	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877092
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.6448
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.255594
Ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.062
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50041
abnormality of the femur	GWASdb SNP-Phenotype Associations	1.0	0.394942
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88692
HDAC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03569
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18712
Ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.996
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2659
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.542
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.838252
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Female germ cell nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
CACFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78009
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46691
RIC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28674
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859871
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00636
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0504
COLO679	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82739
increased hemoglobin content	IMPC Knockout Mouse Phenotypes	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347038
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79746
Superior olivary complex, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28613
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	2.48547
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26355
Cell surface furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
prolonged QT interval	MGI Mouse Phenotype Associations 2023	1.0	null
prolonged	GeneRIF Biological Term Annotations	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.689
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35341
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15727
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00135
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.68311
Temporomandibular joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.37794
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.37548
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16382
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093788
GSE239578_0_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7964
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845217
Female accessory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06962
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46663
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40783
cellular process involved in reproduction in multicellular organism	GO Biological Process Annotations 2015	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05711
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.59802
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1654
recurrent	GeneRIF Biological Term Annotations	1.0	null
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39457
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20609
Lung squamous cell carcinoma_LUSC_TCGA-92-7340-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small testis	MGI Mouse Phenotype Associations 2023	1.0	null
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07905
abnormal male reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2215
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.77173
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
decreased	GeneRIF Biological Term Annotations	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03513
haplotype	GeneRIF Biological Term Annotations	1.0	null
renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098204
embryonic	GeneRIF Biological Term Annotations	1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48324
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60535
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.059043
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835396
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-2226-SM-4AT4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894084
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18243
496100394_TCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07249
SNU601	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86264
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15977
HT-1080	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leiomyoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266558
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
SCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24783
europium-labelled INSL3	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
rxfp2	GeneRIF Biological Term Annotations	1.0	null
abnormal hematopoietic cell number	MPO Gene-Phenotype Associations	1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45704
thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096687
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045087
PDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00675
knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406694
PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
decreased testis weight	MGI Mouse Phenotype Associations 2023	1.0	null
PMC4747358__F3	PFOCR Pathway Figure Associations 2023	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19392
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99039
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0232
hsa-miR-301b	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
within	GeneRIF Biological Term Annotations	1.0	null
CAMTA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69885
AMO1	DepMap CRISPR Gene Dependency	1.0	3.23516
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8573
496100650_TCx_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.58215
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990402
METTL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82773
SW403	DepMap CRISPR Gene Dependency	1.0	5.97043
cumulus-oocyte complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33754
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42346
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901906
founder	GeneRIF Biological Term Annotations	1.0	null
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10574
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal hematopoiesis	MPO Gene-Phenotype Associations	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070697
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
HSDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56883
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4579
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0194
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.137394
abnormal primary sex determination	MPO Gene-Phenotype Associations	1.0	null
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041921
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83974
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.894217
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.531
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0616
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.923278
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal circulating enzyme level	MPO Gene-Phenotype Associations	1.0	null
Liver Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35014
Learning Disorders	CTD Gene-Disease Associations	1.0	1.04757
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.873396
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28427
azoospermia	MGI Mouse Phenotype Associations 2023	1.0	null
Gubernaculum testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.593
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8025
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68G-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085803
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840928
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14517
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SKUT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57078
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44907
synthetic	GeneRIF Biological Term Annotations	1.0	null
RAD21	ChEA Transcription Factor Targets	1.0	null
blastocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35743
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6619
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59454
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.886286
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89797
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.261
GTEX-U4B1-1726-SM-3DB9F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00709
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906047
receptors	GeneRIF Biological Term Annotations	1.0	null
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19566
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.621701
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35594
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68919
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1894
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10016
Disease	Reactome Pathways 2014	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32415
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834821
Decidual cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02997
cannot	GeneRIF Biological Term Annotations	1.0	null
QPCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46157
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63321
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294939
ZNF302	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4329
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Sarcoma_SARC_TCGA-DX-A3LU-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INSL3 B CHAIN DIMER ANALOGUE 8	DGIdb Drug Targets 2026	1.0	1.82524
lumbar spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257572
Mixed gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0026
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914196
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3409
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39668
CMK115	DepMap CRISPR Gene Dependency	1.0	2.68808
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
RPMI-8866	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01206
abnormal mineral homeostasis	MPO Gene-Phenotype Associations	1.0	null
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
[33P]RELAXIN (HUMAN)	DGIdb Drug Targets 2026	1.0	0.91262
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15635
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.520829
hypothesis	GeneRIF Biological Term Annotations	1.0	null
NCI-H508	COSMIC Cell Line Gene CNV Profiles	1.0	2.76305
regulation of cell death	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MO-1126-SM-4DM5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47629
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44078
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5087
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70115
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-11A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428783
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-130a	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.971805
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23148
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE100217_1_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7594
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
SK-N-DZ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10001
Pseudohermaphroditism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.004
relaxin	GeneRIF Biological Term Annotations	1.0	null
receptor activity	GO Molecular Function Annotations 2015	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01027
sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.683103
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain_CT2_Amex 406	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043796
epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.148134
KIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46488
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173222
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39032
TRPS1_Mutation_GDS4493_594_mouse_Whisker pads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PGBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36879
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65023
their	GeneRIF Biological Term Annotations	1.0	null
cell property	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.536229
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0998
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429859
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14346
Non-odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
COLO205	DepMap CRISPR Gene Dependency	1.0	15.0647
Small luteal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58853
EFM19	CCLE Cell Line Gene Expression Profiles	1.0	1.94379
Follicular fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60934
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30176
binds	GeneRIF Biological Term Annotations	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BORC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.653
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4349
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
parallel	GeneRIF Biological Term Annotations	1.0	null
leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.75824
habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284962
abnormal liver morphology	IMPC Knockout Mouse Phenotypes	1.0	null
SERELAXIN	DGIdb Drug Targets 2026	1.0	0.91262
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16979
KMRC2	DepMap CRISPR Gene Dependency	1.0	3.22916
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
abnormal male genitalia morphology	MPO Gene-Phenotype Associations	1.0	null
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.672
Perturb_5347_OE_Gli3T_SRP272033	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.61455
negative regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
increased pulmonary respiratory rate	IMPC Knockout Mouse Phenotypes	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84552
GSE150688_2_v_0_ursolic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29334
Knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
abnormal liver morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06484
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.10268
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06365
cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373868
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074413
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884502
renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126883
Cervical mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3782
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29926
Syndromic microphthalmia 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Lung squamous cell carcinoma_LUSC_TCGA-56-7580-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828043
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943021
decreased IgE level	MGI Mouse Phenotype Associations 2023	1.0	null
TAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18317
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.34314
Partial androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
grl101	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.625
Metanephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047559
causative	GeneRIF Biological Term Annotations	1.0	null
SG231	DepMap CRISPR Gene Dependency	1.0	5.01047
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.32587
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.607818
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.43207
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
Primary motor area, Layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05581
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.924086
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66623
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870042
linked	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59603
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09751
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal lip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7083
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078032
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
endocrine/exocrine gland phenotype	MPO Gene-Phenotype Associations	1.0	null
regulation of camp biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10745
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00815
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
activated	GeneRIF Biological Term Annotations	1.0	null
abnormal circulating alkaline phosphatase level	MPO Gene-Phenotype Associations	1.0	null
M140325	DepMap CRISPR Gene Dependency	1.0	2.07845
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2727
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.64536
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.512
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.092
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
SIN3B	ChEA Transcription Factor Targets	1.0	null
PMC11285331-cd-23-0539_table_s1_suppst1.xlsx-Lost_AR_Peaks-Unnamed_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38648
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.628
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26829
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13223
Cardiac stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
Periodontal ligament cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
identification	GeneRIF Biological Term Annotations	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
repeats	GeneRIF Biological Term Annotations	1.0	null
urinary bladder obstruction	MGI Mouse Phenotype Associations 2023	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1904
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7653
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7923-01A-12R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
support	GeneRIF Biological Term Annotations	1.0	null
Medulary Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03668
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35424
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1862
hsa-miR-148a	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8721
RBPJ	ChEA Transcription Factor Targets	1.0	null
insulinlike	GeneRIF Biological Term Annotations	1.0	null
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
INSL3 [A(5-26):B(7-27)]	DGIdb Drug Targets 2026	1.0	1.82524
adenylate cyclase-modulating g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-8501-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hek-293t cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.90285
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.273367
regulation of cyclic nucleotide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Gonadotrophic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
FOXL2NB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52779
Klinefelter Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29862
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95509
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966325
Acute Myeloid Leukemia_LAML_TCGA-AB-2950-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.550503
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15263
bone disease	GWASdb SNP-Disease Associations	1.0	0.146763
abnormal circulating mineral level	MPO Gene-Phenotype Associations	1.0	null
RFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94713
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4632
Gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E7-01A-31R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59066
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01509
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04594
GTEX-REY6-1126-SM-48FDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04766
Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OC314	DepMap CRISPR Gene Dependency	1.0	8.30733
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.3732
hypospadias	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.772887
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
Neuroactive ligand-receptor interaction	KEGG Pathways 2026	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23867
chr13_31600865_C_T_b38	GTEx eQTL 2025	1.0	1.44013
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
ZNF852	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87569
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33587
susceptibility	GeneRIF Biological Term Annotations	1.0	null
vivo	GeneRIF Biological Term Annotations	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.88678
REV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68429
GJB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12938
similar	GeneRIF Biological Term Annotations	1.0	null
GSE169697,GSE169725_1_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.864
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03986
small gonad	MPO Gene-Phenotype Associations	1.0	null
insights	GeneRIF Biological Term Annotations	1.0	null
trp177	GeneRIF Biological Term Annotations	1.0	null
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5606
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852507
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05473
ZBTB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88537
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3069
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.29201
RASL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13551
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30304
Mandibular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spermatogenic	GeneRIF Biological Term Annotations	1.0	null
without	GeneRIF Biological Term Annotations	1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07091
abnormal circulating sodium level	MPO Gene-Phenotype Associations	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15122
production	GeneRIF Biological Term Annotations	1.0	null
Sweet taste receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30632
Mouse - Motor Cortex - Cluster - Kcnip1+ Layer 6b glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08311
increased circulating lipase level	MPO Gene-Phenotype Associations	1.0	null
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089059
increased circulating calcium level	MGI Mouse Phenotype Associations 2023	1.0	null
developmental process involved in reproduction	GO Biological Process Annotations 2015	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1288
bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.530768
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42346
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835269
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16604
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1444
components	GeneRIF Biological Term Annotations	1.0	null
GTEX-XGQ4-0926-SM-4AT4U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59714
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.505739
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55176
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.242595
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0383
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4732
Gonadoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
osteoporosis	GeneRIF Biological Term Annotations	1.0	null
confirmed	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-2K-A9WE-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217762
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985444
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8156
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	2.12978
ectodomain	GeneRIF Biological Term Annotations	1.0	null
MET_knockout_261_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.58651
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medullary carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47607
IOMMLEE	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10241
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.434906
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72622
positive regulation of purine nucleotide biosynthetic process	GO Biological Process Annotations 2015	1.0	null
TAS2R5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88722
abnormal sperm number	MPO Gene-Phenotype Associations	1.0	null
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
RAB3A_Mutation - D77G point mutation_GDS2483_698_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50295
GTEX-XUZC-0626-SM-4BOPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06579
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53702
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68835
Prune belly syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69712
hermaphroditism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.389281
LAMTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82828
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051814
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29535
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.049
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3418
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00741
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.68404
496100560_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82952
Idiopathic juvenile osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5076
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6602
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97056
OVSAHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61159
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94624
Anovulation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
factors	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4301	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PAX3	ChEA Transcription Factor Targets	1.0	null
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840642
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2619
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17348
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15404
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.7929
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845477
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60092
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9436
testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.299092
Spermatic cord torsion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.103
abnormal inguinal canal morphology	MGI Mouse Phenotype Associations 2023	1.0	null
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77297
cryptorchidism; klinefelter syndrome	GAD Gene-Disease Associations	1.0	null
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52449
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30423
ile179	GeneRIF Biological Term Annotations	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825141
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37322
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LC-1-SQ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7809
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	1.55155
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974946
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824375
abnormal sex gland morphology	MPO Gene-Phenotype Associations	1.0	null
Androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.184
events	GeneRIF Biological Term Annotations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59848
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.628
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
SW1116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94249
finnish	GeneRIF Biological Term Annotations	1.0	null
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6906
Low-density lipoprotein (LDL) receptor class A, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
either	GeneRIF Biological Term Annotations	1.0	null
regulation of purine nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72961
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0111
cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	2.24471
regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
abnormal protein level	MPO Gene-Phenotype Associations	1.0	null
HOXC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97333
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056613
protein-lipid complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.396648
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33537
activating	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22888
vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.087862
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracranial hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180367
EUROPIUM-LABELLED INSL3	DGIdb Drug Targets 2026	1.0	1.82524
absent germ cells	MPO Gene-Phenotype Associations	1.0	null
system	GeneRIF Biological Term Annotations	1.0	null
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	3.50699
genderspecific	GeneRIF Biological Term Annotations	1.0	null
cryptorchism	MPO Gene-Phenotype Associations	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	0.974293
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112159
Seminal plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-0226-SM-3LK61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60482
PMC9170110-pgen.1010161.s047.xlsx-DBP_DEP-nearestGene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
496100540_TCx_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.85629
binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4690-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J8-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37147
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormality of the lower limb	GWASdb SNP-Phenotype Associations	1.0	0.28113
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.52553
primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169205
ventral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62296
peptide	GeneRIF Biological Term Annotations	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.628
EZH2	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28331
hsa-miR-4658	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
abnormal calcium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633144
increased hemoglobin content	MGI Mouse Phenotype Associations 2023	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29452
Posterior limiting nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05838
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16756
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00273
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
Medication use (agents acting on the renin-angiotensin system)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
CYCLIC INSL3 B-CHAIN ANALOGUE 6	DGIdb Drug Targets 2026	1.0	1.82524
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107972
native	GeneRIF Biological Term Annotations	1.0	null
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
itself	GeneRIF Biological Term Annotations	1.0	null
ZNF132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99372
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33651
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cause	GeneRIF Biological Term Annotations	1.0	null
decreased male germ cell number	MGI Mouse Phenotype Associations 2023	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54895
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5649
positive regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.13221
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.638809
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59848
considered	GeneRIF Biological Term Annotations	1.0	null
Primary motor area, Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07085
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49382
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.671159
theca cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.93577
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058382
Sperm principal piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
Pulvinar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
mantle zone of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26812
cellular_component	GO Cellular Component Annotations 2015	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_14_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058983
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.42129
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.766539
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2061
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.122554
skeleton phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17435
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6904
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15459
male infertility	MPO Gene-Phenotype Associations	1.0	null
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07005
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057483
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59389
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056499
PARP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17428
SARS-CoV MA15_Day1-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.67929
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.53093
LTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38235
male infertility	MGI Mouse Phenotype Associations 2023	1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80671
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.968814
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08689
increased circulating lipase level	MGI Mouse Phenotype Associations 2023	1.0	null
TFAP2C	ChEA Transcription Factor Targets	1.0	null
increased erythrocyte cell number	MPO Gene-Phenotype Associations	1.0	null
INSL3	Pathway Commons Protein-Protein Interactions	1.0	null
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC12328722-41467_2025_61712_MOESM3_ESM.xlsx-D9_Pathway_enrichment_results-Unnamed_5_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
consequently	GeneRIF Biological Term Annotations	1.0	null
increased hematocrit	IMPC Knockout Mouse Phenotypes	1.0	null
reproductive organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.275801
PMC6202145__F1	PFOCR Pathway Figure Associations 2024	1.0	null
SKLMS1	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
(DES 1-8) A-CHAIN INSL3 ANALOGUE	DGIdb Drug Targets 2026	1.0	1.82524
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05711
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
PK1	CCLE Cell Line Gene Expression Profiles	1.0	1.58986
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1074
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82142
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986805
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0539
involving	GeneRIF Biological Term Annotations	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949593
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13094
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52367
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.637597
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.36
male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069494
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8378
PMC8370976-41467_2021_24932_MOESM6_ESM.xlsx-Annotation-Supplementary_Data_4_GO_and_metascape_analysis_of_the_genes_downregulated_in_U87_cells_upon_ZNF768_knockdown_ZNF768	Rummagene Transcription Factor Associations 2026	1.0	null
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07569
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.50339
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
population	GeneRIF Biological Term Annotations	1.0	null
isoform	GeneRIF Biological Term Annotations	1.0	null
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06454
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09848
stimulate	GeneRIF Biological Term Annotations	1.0	null
insl3	GeneRIF Biological Term Annotations	1.0	null
WM88	DepMap CRISPR Gene Dependency	1.0	4.79701
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01331
Medication use (calcium channel blockers)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7652-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307528
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93878
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.200331
YH13	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal hemoglobin	MPO Gene-Phenotype Associations	1.0	null
icSARS CoV_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.12853
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.194
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7363
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34098
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2914-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879159
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19626
LUDLU1	DepMap CRISPR Gene Dependency	1.0	2.10722
PHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83291
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2014	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996547
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22455
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61075
abnormal testis size	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-22	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
46,XY sex reversal 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.59
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399114
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50432
OCUBM	DepMap CRISPR Gene Dependency	1.0	2.16556
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345188
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3376
residues	GeneRIF Biological Term Annotations	1.0	null
TTLL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47942
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
Low-density lipoprotein (LDL) receptor class A repeat	InterPro Predicted Protein Domain Annotations	1.0	null
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Wnt-Frizzled-LRP5/6 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.061
NCIH69	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61101
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0278
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15685
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24556
Cryptorchidism, unilateral or bilateral	ClinVar Gene-Phenotype Associations	1.0	null
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PL4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62525
abnormal hematocrit	MPO Gene-Phenotype Associations	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43224
GPX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83119
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4506
SNU1196	CCLE Cell Line Gene Expression Profiles	1.0	1.41043
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Leydig cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.753
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC4747358__F3	PFOCR Pathway Figure Associations 2024	1.0	null
descend	GeneRIF Biological Term Annotations	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0345
PMC9437808-mmc5.xlsx-Upstream_regulators-IPA_Upstream_regulator_analysis_genes_that_were_downregulated_in_the_cf-mRNA_of_AZD_treated_group_at_2-hour_post_LPS_time_point_were_used_as_inputs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.853256
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_30_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
androgen insensitivity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.419892
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Myometrial Relaxation and Contraction Pathways(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
Myometrial Relaxation and Contraction Pathways(Mus musculus)	WikiPathways Pathways 2014	1.0	null
PMC7432388__F2	PFOCR Pathway Figure Associations 2024	1.0	null
SIX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.037
JAG1_OE_GDS3571_40_human_endometrial stromal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
represent	GeneRIF Biological Term Annotations	1.0	null
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249653
SW1783	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98002
Perturb_13013_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.3846
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	2.18465
Leydig cell hypoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26589
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49428