association	dataset	threshold value	standardized value
PF-00539758-00-6421	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2525
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.845518
sulfachlorpyridazine-3769	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1171
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13131
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64728
skin	HPA Tissue Gene Expression Profiles	1.0	1.9538
XPOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86531
Dentin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.912
SKNEP1	DepMap CRISPR Gene Dependency	1.0	7.3412
SETMAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49428
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
prochlorperazine-1156	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.99675
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33322
Symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.85
carbarsone-1313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70161
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05187
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40033
pheneticillin-6239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5011
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13008
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07483
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0908
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21931
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.941526
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
genistein-1015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32658
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999407
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30243
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GE-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.995977
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57183
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.02686
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.62184
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97476
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
(+)-chelidonine-6236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PABPC1L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01154
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.939818
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15519
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06286
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09543
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888275
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12607
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
middle frontal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09185
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03983
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110178_5_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82215
JUND	ENCODE Transcription Factor Targets	1.0	null
PLAGL2_deficiency_GDS3010_139_mouse_embryonic small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.878091
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26221
Prestwick-860-5679	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37673
CHD2	ENCODE Transcription Factor Targets	1.0	null
ZNF257	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4838
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	54.9966
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06732
GFI1_KO_GDS4204_147_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00467
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16239
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52943
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WX-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10194
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70423
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.856
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
H3K36me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10717
DICER1_KO_GDS4504_582_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OBF-1_NULL MUTATION_GDS3473_571_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08392
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17490_KO_Krt13_SRP248501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.47486
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF229	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23229
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cyproterone-3545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE199081_0_v_1_insr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09831
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31891
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_166_KD_Mir21_SRP361611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.15387
AHCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03014
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971245
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950716
SPI1	ChEA Transcription Factor Targets	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71186
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864864
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18023
HEATR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55145
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18691
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195786_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98647
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904033
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999407
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
18614019-TableS4d	GeneSigDB Published Gene Signatures	1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Universal_Human_Reference	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.96259
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
Perturb_16966_KD_Ezh2_SRP050542	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4186
GSE183271_4_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Parenchyma of thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74786
Telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
496100552_PCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2927
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22959
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4822-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
macular degeneration	GAD Gene-Disease Associations	1.0	null
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.941913
Perturb_2896_KO_Ghrh_SRP241951	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.66462
u937	HPA Cell Line Gene Expression Profiles	1.0	1.21258
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.3636
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07444
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34613
SNU601	DepMap CRISPR Gene Dependency	1.0	2.03359
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71315
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80633
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
DNAAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65061
CRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81753
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7725
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD54L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58959
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93168
cytisine-1766	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97741
Perturb_16403_KO_Grpel1_SRP363877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.11744
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.537755
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999407
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23476
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08097
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57727
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956159
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47565
SALL4	ChEA Transcription Factor Targets	1.0	null
Sporulated oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.457
MFSD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42979
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_17338_KO_Mageb4_SRP259999	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.2885
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9371
chlortalidone-6800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ulcerative colitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.4301
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	2.11445
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.65668
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0376
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880223
Sarcoma_SARC_TCGA-QC-A7B5-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.133658
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12122
etamivan-7260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100290_PCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2684
ricinine-6206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KRTAP13-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09157
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10861
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96136
Acute Myeloid Leukemia_LAML_TCGA-AB-2990-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BMAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6874
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30428
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.66938
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00404
MEL270	DepMap CRISPR Gene Dependency	1.0	5.98447
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R9-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27585
Thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5924
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K36me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30539
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01512
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54D-01A-21R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9475
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12832
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F2-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macular degeneration	GWASdb SNP-Disease Associations	1.0	0.912987
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	9.29758
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-BatSRBD_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78107
hsa-miR-1224-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.8497
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.845912
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
WHRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99069
urapidil-5295	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_CBX8_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.839026
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926371
ritodrine-4619	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73705
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60371
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10711
Perturb_1431_KO_Prmt7_SRP362551	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13739
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid_homo sapiens_gpl570_gse14973	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17789
eye disease	GWASdb SNP-Disease Associations	1.0	0.136017
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COL1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47188
tetracycline-6233	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13141
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53777
PGM2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47571
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PSMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44051
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880873
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61215
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85278
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63299
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17309
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.399
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81802
ZFP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18518
Plasmodesma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.04
ATG9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08417
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13479
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
phenazopyridine-6234	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57533
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Takayasu Arteritis	DisGeNET Gene-Disease Associations	1.0	null
GSE128333_4_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53883
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.930362
Perturb_13486_KO_1810027O10Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33884
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21975
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.11946
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.08076
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
Lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
Perturb_6989_KO_Ptcd1_SRP120583	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.74215
ZFX	ChEA Transcription Factor Targets	1.0	null
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41125
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40259
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16994
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3733_KO_Trp53_SRP296860	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.2752
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.96936
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03756
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SW1990	CCLE Cell Line Gene CNV Profiles	1.0	2.44326
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16691
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.32441
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855243
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.033775
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17243
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33091
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51346
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.702178
SERPINB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92333
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07977
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
YY1	ChEA Transcription Factor Targets	1.0	null
H2BC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95119
GSE154246_2_v_3_haspin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46766
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.053062
Lung squamous cell carcinoma_LUSC_TCGA-85-8070-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.975982
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48868
GTEx Brain 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	6.17551
POLR2A	ENCODE Transcription Factor Targets	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16714
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80424
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58449
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888275
7-aminocephalosporanic acid-1322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	3.11101
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43463
ZFX_KO_GDS2718_150_mouse_embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25936
ChIP_SALL4_18804426	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06412
MDAMB231	CCLE Cell Line Gene CNV Profiles	1.0	1.39147
Perturb_15250_KO_Dnmt3a_SRP386956	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00781
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01335
5255229-833	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.73155
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886527
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74017
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.989591
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47307
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48274
Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2829
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19485
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856572
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05311
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mp88	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
C84	DepMap CRISPR Gene Dependency	1.0	2.47861
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92216
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2494
asiaticoside-7004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6209
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17434
retinal disease	GWASdb SNP-Disease Associations	1.0	0.226475
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.904042
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP-690334-01-4380	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
prednisolone-2393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7344
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31252
19334046-TableS3b	GeneSigDB Published Gene Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12063657-sciadv.adr3173_sm.pdf-21-RFX3_RFX3	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9648
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3275
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68862
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12876
5211181-834	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10018
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF829	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49497
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15234
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6291
GSE157911_1_v_0_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pivmecillinam-7312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_13342_KD_Smarce1_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.36481
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEx Brain 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	6.4654
LYL1	ChEA Transcription Factor Targets	1.0	null
Arthritis, Psoriatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
fulvestrant-6955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
isocarboxazid-7383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18642
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
D341Med	DepMap CRISPR Gene Dependency	1.0	2.26272
KLF1-20508144-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27661
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37587
khellin-1504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	3.49441
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.766228
ZNF618	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22653
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW948	DepMap CRISPR Gene Dependency	1.0	4.45267
GTEx BloodVessel 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	18.5433
Goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
H3K36me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PCDHB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61382
syrosingopine-6213	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24293
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06093
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PRMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83687
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GMEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49397
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9709_KO_Nox4_SRP330045	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.71492
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
POLR2A_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836167
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0243
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33223
GSE188933,GSE188934_1_v_2_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.966833
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.948142
GEMIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04227
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44012
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.989999
CARD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52341
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08683
Cervix disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39057
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49846
XRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65371
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40G-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4424	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17888
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15976
MOSPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.55949
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.25266
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.797
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.00007
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888275
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6952_KO_Rbm20_SRP328560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.67913
glimepiride-4973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82584
Perturb_216_KO_Gpd2_SRP361070	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.64281
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.920755
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1121
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
flecainide-4318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25902
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81046
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.842531
Perturb_10617_OE_Nrf2_SRP161960	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.65015
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0821
NCIH510	DepMap CRISPR Gene Dependency	1.0	3.41558
PHA-00665752-6578	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4-hydroxyphenazone-1997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54576
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.985109
Brain Lower Grade Glioma_LGG_TCGA-DB-A75P-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88607
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.20017
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87406
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HK-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trichostatin A-6579	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NGP	DepMap CRISPR Gene Dependency	1.0	3.34984
CCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4579
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06396
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22851
RDES	DepMap CRISPR Gene Dependency	1.0	2.79407
H3K36me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49083
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18306
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.41412
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17875
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3908
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41456
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20529
ARMCX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59088
NPTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Symplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.965
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34283
EMTOKA	DepMap CRISPR Gene Dependency	1.0	2.16686
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
lithocholic acid-3899	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31749
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.37283
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.8729
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8855
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Clozapine-induced agranulocytosis/granulocytopenia in treatment-resistant schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
CLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81956
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3298
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.0569
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05058
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16674
gallamine triethiodide-6215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
CRCGN015_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10577
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophagitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
Arthritis, Rheumatoid	HuGE Navigator Gene-Phenotype Associations	1.0	null
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39658
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
convolamine-1779	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
levocabastine-7249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SARS-dORF6_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52425
16,16-dimethylprostaglandin E2-6562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838618
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22102
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97829
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.55251
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31891
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.10792
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.54258
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931192
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09511
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CNKSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13456
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11277
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.611
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79449
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08938
LASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76543
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51058
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.843095
ChIP_ZFX_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903739
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58675
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47565
thiostrepton-2462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Botryoid rhabdomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23727
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1421
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16813
HAUS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30281
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24858
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2697
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40657
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.164
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73673
TCIRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60988
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039405
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130956_0_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57415
Perturb_13330_KD_Nfat5_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.85432
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998103
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	2.4616
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2339
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25563
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225656_0_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0529
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4XJ-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30261
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06017
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45239
RNF123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.485
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54576
monensin-7402	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NZOV9	DepMap CRISPR Gene Dependency	1.0	8.59067
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.20135
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.37547
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23057
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48552
Perturb_16628_KD_Sod1_SRP217736	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.47493
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Esophageal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81864
paracentral lobule, anterior part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905574
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1757
hsa-miR-4419b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lhx8_18509161_newborn_ovary_lof_mouse_gpl1261_gds3254	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.012982
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59067
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42918
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31749
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77188
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29399
CHCHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27081
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.325
ATP8B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07823
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846705
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46655
Perturb_14939_OE_hPRDM15_SRP182668	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67325
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1861
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21207
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971245
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16492
Perturb_4468_KO_Cnr1_SRP346447	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.76659
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
YWHAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80493
wortmannin-1023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18742
Leprosy	HuGE Navigator Gene-Phenotype Associations	1.0	null
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
MON	DepMap CRISPR Gene Dependency	1.0	4.74582
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
RELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61542
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13916
BICR56	DepMap CRISPR Gene Dependency	1.0	2.69825
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.90281
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65663
brain_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.14902
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89373
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.954631
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9944
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27222
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58459
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4285
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16258
ARMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87254
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937904
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21604
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23316
SEC14L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06658
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4734
mRNA_YY1_22210892	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
COGE352	DepMap CRISPR Gene Dependency	1.0	2.28595
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266558
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0652
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48686
PFSK1	DepMap CRISPR Gene Dependency	1.0	5.70895
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09907
Leaf vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
Y79	DepMap CRISPR Gene Dependency	1.0	2.57908
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20768
symmetric, GABA-ergic, inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.242
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897956
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16521
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14021
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.891169
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91694
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57431
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45773
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1836	DepMap CRISPR Gene Dependency	1.0	3.76096
KIF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27838
NPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3391
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
atractyloside-7393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.9242
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4819-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38411
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31749
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1267	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Nephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
TCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21386
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29857
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32581
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7601
phenelzine-3802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33736
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87461
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82323
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05365
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02294
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50819
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999407
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.922342
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.55896
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5369
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
paracentral lobule, anterior part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.941796
P4HA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5596
hsa-miR-654-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_13348_KD_Taf6l_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86368
erastin-6417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995509
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2298
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57104
MYC	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85772
Perturb_4528_KD_Chaf1a_SRP060878	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.12162
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.906166
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.9952
PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SIRT3_KO_GDS4058_454_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8593
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63883
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NXPE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30472
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16951
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.56259
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.059772
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883281
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77877
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.3262
hsa-miR-4328	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
minocycline-7436	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.937424
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A40J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09458
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.21089
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23599
KMM1	DepMap CRISPR Gene Dependency	1.0	3.15817
NUP88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16939
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9951
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24388
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.914195
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV318	DepMap CRISPR Gene Dependency	1.0	4.40552
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19675
tcf3_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.444971
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943953
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040003
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90111
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.913845
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15325_KO_Setd2_SRP251920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.54975
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.941298
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77732
Perturb_11828_KO_Ptpdc1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.33485
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31325
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.0699
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42201
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28246
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00734
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25004
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07313
GSE125211_2_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33667
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
MARVELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50759
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.971039
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.57904
GINS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31882
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18619
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29111
Perturb_10217_KO_Csnk1a1/Trp53_ERP021472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.53599
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43007
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.851002
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_8674_KD_CircINSR_SRP365091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.7009
nomegestrol-6362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE185944_2_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59319
levomepromazine-3440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03788
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8315
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67473
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23261
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.834628
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5325
Breast ductal adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
RBM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54489
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.829654
Perturb_203_KD_Id1/ld3_SRP193147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89214
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.40601
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847385
Perturb_16836_KO_Lats1/Lats2_SRP119763	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58453
rotenone-5943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JM-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.217042
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917384
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
resveratrol-2865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE119978,GSE180930_2_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93487
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69191
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931515
Cutaneous lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
RNA polymerase IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
FLI1	ChEA Transcription Factor Targets	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5696
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.2322
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35467
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71965
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40033
thyroid_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.11109
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18537972-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
KML1	DepMap CRISPR Gene Dependency	1.0	5.60826
increased bone mineral density	MGI Mouse Phenotype Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3160-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52346
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60793
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.51655
SNU1077	DepMap CRISPR Gene Dependency	1.0	2.57713
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43524
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80227
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTEN hamartoma tumor syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
H3K36me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.998878
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68555
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.74417
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53491
arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.28831
RELCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2816
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3017_KD_Ttn_SRP222910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.21524
TVP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11524
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78903
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0019
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.13195
Suppressor APC domain-containing protein 1/2	InterPro Predicted Protein Domain Annotations	1.0	null
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	2.52803
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54295
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.3636
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_11803_KO_Gb6_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.64951
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-3167	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40033
GTPase activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93429
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9713
STON1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13697
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848591
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60262
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04202
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the macula	GWASdb SNP-Phenotype Associations	1.0	0.802966
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208435_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13795
DACT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94563
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.910845
butoconazole-3288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4492
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27409
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
iopanoic acid-6348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20371
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92433
RIOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78931
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998103
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_4474_OE_Smn_SRP258674	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.35563
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39832
skbr3	HPA Cell Line Gene Expression Profiles	-1.0	-1.38514
SAP30L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91505
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0605
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90323
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.617
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Stromule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.152
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25933
RL	DepMap CRISPR Gene Dependency	1.0	3.74321
CRCGN015_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26005
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.61138
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.986207
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64546
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98278
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4P0-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MC1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13001
MUTZ8	DepMap CRISPR Gene Dependency	1.0	2.38831
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848591
WDR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96508
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40246
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
mRNA_KAT5_22196727	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Skin cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.584
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.55951
thymus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.902481
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.69956
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26592
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999407
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.885145
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51067
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2831
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897505
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9722
Sertoli-Leydig cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
PAQR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51747
ACTMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15255
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5782
RARA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83112
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86488
ZFX-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_15266_KD_Csde1_SRP288392	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.68768
PMC2820592-NIHMS144142-supplement-8.xls-LMS_SAM_3-GENES_HIGHLY_EXPRESSED_IN_GROUP_III_LMS_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847918
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07899
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0572
Acute Myeloid Leukemia_LAML_TCGA-AB-2919-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24258
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.80037
FZR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19368
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29342
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.874203
trichostatin A-1785	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pentolonium-7375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.65137
16651409-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
Asthma (childhood onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pendred Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
bethanechol-3537	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.57371
Lung adenocarcinoma_LUAD_TCGA-78-8662-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.75177
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.14505
PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52748
Eosinophilic esophagitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.634
u87	HPA Cell Line Gene Expression Profiles	-1.0	-0.938991
MutSbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
USP46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42472
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95517
SRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68337
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.38539
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	1.11684
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SIRT3_KO_GDS4058_16_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834009
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.4304
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886527
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3276
MYOG	ENCODE Transcription Factor Targets	1.0	null
Takayasu's arteritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.921745
ethisterone-3783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39378
BRCA1	JASPAR Predicted Transcription Factor Targets	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15659
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1679
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9274
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mecamylamine-7263	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45901
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41199
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22447
cochlear nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28418
FBXL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26575
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16521
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09938
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.64532
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nuclear telomere cap complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.305
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09865
F36P	DepMap CRISPR Gene Dependency	1.0	4.55994
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80672
angular gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839198
Perturb_6950_KO_Rbm20_SRP328560	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64987
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L363	DepMap CRISPR Gene Dependency	1.0	5.04704
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31749
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908344
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00452
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.01301
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07658
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0277
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47823
trichostatin A-7043	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lomustine-7045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91695
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02116
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.8405
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223334_1_v_2_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mesophyll	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
hsa-miR-4478	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NELFE	ENCODE Transcription Factor Targets	1.0	null
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24263
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.43676
NAA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05559
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43754
ZNF420	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2089
Lung adenocarcinoma_LUAD_TCGA-L9-A444-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.034699
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53603
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13938
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	147.149
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50071
vascular disease	GWASdb SNP-Disease Associations	1.0	0.616754
GSE172295_1_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29156
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.878
TLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16017
RBM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82096
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CCDC77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03211
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72564
Y-27632-832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SYT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60114
ADO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50603
DICER1_KO_GDS4504_584_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33413
Perturb_205_KD_Robo1/Id1/ld3_SRP193147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.51586
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.296
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38981
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51168
CEBPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31942
SOX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26089
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54015
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A69Q-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16548
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04945
acepromazine-1777	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
MCTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49044
mRNA_TCF3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE146045_1_v_0_lama3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12029
Perturb_16925_KO_Hete_SRP220444	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.94329
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3537
carbamazepine-835	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.922803
Uterine cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1762
SGPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83261
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17635
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05843
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27409
Uterine Carcinosarcoma_UCS_TCGA-N5-A59E-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.94
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45421
SCCOHT1	DepMap CRISPR Gene Dependency	1.0	7.13952
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34287
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30542
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.64034
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FD-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.69038
u266	HPA Cell Line Gene Expression Profiles	1.0	0.824638
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.64014
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.506
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54991
GCIY	DepMap CRISPR Gene Dependency	1.0	4.83122
Lung squamous cell carcinoma_LUSC_TCGA-58-A46J-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HE-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.02455
SETDB1	ChEA Transcription Factor Targets	1.0	null
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6146
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72461
KAT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16125
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67724
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16543
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048574
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26498
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888275
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09613
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03651
MAX	ENCODE Transcription Factor Targets	1.0	null
increased bone mineral density	IMPC Knockout Mouse Phenotypes	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EM2	CCLE Cell Line Gene CNV Profiles	1.0	2.09723
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54241
UMUC3	DepMap CRISPR Gene Dependency	1.0	2.78792
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28088
SOX9	ChEA Transcription Factor Targets	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11228
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91583
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Psammomatous meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01609
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.92433
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
GSE199874_3_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GOPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09521
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15524
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35033
CAMSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07204
Brain Lower Grade Glioma_LGG_TCGA-WY-A858-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sulfamethoxazole-7366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.968201
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
0173570-0000-7391	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE145476_2_v_3_hopx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63645
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.136017
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.98275
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41A-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5673
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20375
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21076
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.577
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.097542
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00806
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-CoV_84Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83083
brompheniramine-1335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
ANG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31969
PEA1	DepMap CRISPR Gene Dependency	1.0	5.43743
ATP6V0E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10357
genistein-1660	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.391513
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33985
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46569
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00925
MAVS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43109
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41459
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MIS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22488
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.923112
macular degeneration	GWASdb SNP-Phenotype Associations	1.0	0.802966
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30021
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887264
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7151
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887116
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.907138
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887153
PMC11252405-41467_2024_50426_MOESM4_ESM.xlsx-Fig_S4c-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79298
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.956159
KCTD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47706
telomere-telomerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.083
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8565
MAZ	ENCODE Transcription Factor Targets	1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25566
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38171
ATP13A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47761
Lung adenocarcinoma_LUAD_TCGA-97-A4M2-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9275
sulfacetamide-6349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3435_KO_Bmal1_SRP359933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.4471
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01984
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14989
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845316
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.87722
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
fosfosal-4239	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.041231
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73084
KYSE270	DepMap CRISPR Gene Dependency	1.0	3.57019
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
age-related macular degeneration	GWASdb SNP-Phenotype Associations	1.0	0.802966
GSE225218_2_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.84253
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01411
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16492
HEYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0443
Central nervous system sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908442
NKX2-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19741
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4671
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMBIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82525
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.846638
meclofenoxate-3405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
norethisterone-2383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
Perturb_7096_KO_Eif2ak3_SRP271084	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.90416
SLC16A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06694
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01011
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Up_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
famprofazone-4309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68503
primary auditory cortex (core)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4682
Feeling worry	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
Head and Neck squamous cell carcinoma_HNSC_TCGA-CX-A4AQ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1077	CCLE Cell Line Gene CNV Profiles	1.0	1.43681
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6UY-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63805
EP300	ChEA Transcription Factor Targets	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.42951
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.923408
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61916
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arachidonic acid-604	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02267
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.78775
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Thyroid follicular epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4622
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09429
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.1862
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4073_KO_Bcl11b_SRP260102	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.0972
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67025
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10323_KO_MYC/Setd2_SRP310502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.33855
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40234
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
age related macular degeneration	GWASdb SNP-Disease Associations	1.0	0.912987
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56775
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15360_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.78866
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29883
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02327
RAD21	ENCODE Transcription Factor Targets	1.0	null
Pulmonary blastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
Perturb_15359_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.14534
CORL279	DepMap CRISPR Gene Dependency	1.0	2.99664
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62805
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.846217
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.16638
bone marrow	HPA Tissue Gene Expression Profiles	1.0	1.15938
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04077
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40783
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
Perturb_17493_KO_Gpr115_SRP275685	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39673
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847691
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32413
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01113
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
A-CA-04-2009(H1N1)_36Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.06436
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886527
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2551
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.46284
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
postcentral gyrus, right, bank of the posterior central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1027
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.11186
blebbistatin-837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17373
MYB_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886527
Perturb_11776_KO_Abca8b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.45475
WNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26378
OTUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20393
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.933466
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52765
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4619
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9337
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03601
CNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6811
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44238
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
bumetanide-2409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4561
Perturb_17276_KO_Uxt_SRP135119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45292
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70161
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03089
piperine-1327	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44149
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40878
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930339
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
quinisocaine-2807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.6364
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.6975
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25804
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05437
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886527
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00275
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05326
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.824477
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17365
Perturb_4679_KO_Dppa2/Dppa4_SRP218369	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.01295
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53425
Perturb_16400_KO_Pak1_SRP351351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.77261
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6236
IRF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34629
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53135
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40362
TIGD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14338
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241701_1_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-0.954873
capsaicin-4612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_MEF2C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27164
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05037
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5868
Lipoadenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
MAP3K21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64453
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98028
ZNF470	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44205
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04699
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Membranous glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
APLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03241
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100361_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06461
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40033
amprolium-1479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE185744,GSE185747_0_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31545
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15518
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39704
GSE76425_0_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3175	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5235
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
TCEAL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03628
hsa-miR-345	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pontine reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01713
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4322
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
GSE126219_0_v_1_haloperidol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893502
FOXM1-25889361-OE33-AND-U2OS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70681
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molsidomine-2862	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OGFOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53453
Perturb_13328_KD_Mnt_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67552
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.866374
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158815_5_v_0_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06885
SBK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28812
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66761
GSE168676_2_v_3_dach1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-A4AE-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6549
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kanamycin-4625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_10644_KO_Gclc_SRP321080	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.81759
DPP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.9858
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193624_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.09904
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6208
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.977725
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SALL4-18804426_ESC-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4185
gp16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.526
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16627
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23855
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21515
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03614
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.26343
EEF1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47438
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53761
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66141
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JHESOAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.95836
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.217042
b220.bcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14189
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67091
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49292
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872882
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-876-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33459
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9755
0175029-0000-4713	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47552
NEUROD1_Deficiency_GDS3000_612_mouse_Pineal glands of neonates	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10708
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18222
EIF2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74606
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908344
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17676
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cowden syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.193285
PF-00539758-00-6416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peeling skin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21949
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971906
Perturb_10616_KO_Ttn_SRP136441	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.09595
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87654
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0038
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67355
Pulse pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43816
Adrenocortical carcinoma_ACC_TCGA-OR-A5LD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4122
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7856
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91946
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48247
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14434
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30816
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1232
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07716
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59967
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836673
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27296
Basal cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.584
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27762
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.921855
ABRACL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32966
H3K36me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873985
NUDT21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80526
retinal degeneration	GWASdb SNP-Disease Associations	1.0	0.353334
Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IFI16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71496
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5047
5707885-6438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16626_KD_Sod1_SRP217736	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.93663
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.97
KLF1	ChEA Transcription Factor Targets	1.0	null
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.927394
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1057
Systolic blood pressure	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.722185
MEC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33072
Perturb_2272_KO_Mettl3_SRP110576	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.01851
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4875-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83396
NCIH1092	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60803
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4638-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.584
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Perturb_17038_KD_Ikaros_SRP035941	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NEUROG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18125
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	1.2335
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881135
Vagina	GTEx Tissue Gene Expression Profiles 2023	1.0	1.31326
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
hsa-miR-4531	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38839
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.099017
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9937
SP in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825881
GSE157296,GSE157298_4_v_2_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1434
LMO2	ChEA Transcription Factor Targets	1.0	null
SARS-dORF6_48Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65559
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52041
NR2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28233
SARS-CoV_48Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.24854
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.991251
orlistat-6420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49412
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37104
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.311698
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
NANOG	ChEA Transcription Factor Targets	1.0	null
bufexamac-2382	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
probucol-3223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80725
PPP1R3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84351
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894411
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866425
hsa-miR-4733-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
acemetacin-7442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
tetrahydroalstonine-6209	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.830784
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.852391
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64663
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43885
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888275
SOX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1688
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66141
JJN3	CCLE Cell Line Gene CNV Profiles	1.0	1.87272
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46811
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.974852
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0557
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOMEZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14021
Psammoma body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.93034
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08401
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.16326
ACF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.664
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29915
POU5F1	ChEA Transcription Factor Targets	1.0	null
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74886
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
amodiaquine-3186	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE76425_1_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06418
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945467
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02436
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05225
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9102
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.888617
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18929
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8498_OE_Sox9_SRP375106	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.47679
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10665
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23222
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.28366
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.51051
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
Perturb_10418_KD_Nuak1_ERP105467	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.78161
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49083
LEPROTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04286
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MKKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25097
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08254
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931192
SCA1_Knock-in_GDS1756_232_mouse_Cerebellum tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Carney complex	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
novobiocin-4569	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33148
hsa-miR-3929	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RS-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81141
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93001
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C6orf141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74672
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887708
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
MECOM	ChEA Transcription Factor Targets	1.0	null
fusiform gyrus, right, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.856266
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RASL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27169
NEU	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1024
VPS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98919
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29898
19946333-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.04848
Glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.946
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96348
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28047
RCOR1	ENCODE Transcription Factor Targets	1.0	null
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85818
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74285
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31028
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7083
dexibuprofen-5311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
clozapine-1009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6436
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89641
SMC3	ENCODE Transcription Factor Targets	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9458
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.944401
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12356
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.944367
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.999
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48744
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.84551
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80863
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70204
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-CoV_60Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.21861
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29751
Perturb_12698_KO_Ezh2_SRP222765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.66493
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
DICER1 syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
degeneration of macula and posterior pole	GWASdb SNP-Disease Associations	1.0	0.912987
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.867
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rat-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
Lung adenocarcinoma_LUAD_TCGA-62-A46S-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51586
abnormal eating behavior	GWASdb SNP-Phenotype Associations	1.0	0.523576
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.8636
AAGAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77462
tolbutamide-4362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_4021_KO_Bcl11b_SRP260102	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.9191
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49083
KYSE450	DepMap CRISPR Gene Dependency	1.0	6.0347
AIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08946
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.37395
TAL1	ChEA Transcription Factor Targets	1.0	null
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57526
Cervical cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.133658
DNAJA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17312
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944098
fusaric acid-1308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52907
Lung adenocarcinoma_LUAD_TCGA-05-4396-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79752
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1722
esculetin-7459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0916
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34537
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8151
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5179
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44855
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99246
A427	DepMap CRISPR Gene Dependency	1.0	3.05029
FNIP-folliculin RagC/D GAP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68C-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	DepMap CRISPR Gene Dependency	1.0	2.82498
Lung adenocarcinoma_LUAD_TCGA-62-A46V-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33653
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92453
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ciclacillin-3882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.42269
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.01231
CCSW1	DepMap CRISPR Gene Dependency	1.0	2.30086
639V	DepMap CRISPR Gene Dependency	1.0	2.82905
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00363
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5578
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R3-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57568
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
thioridazine-5916	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2757
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9331
CBFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01655
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35854
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34989
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76008
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.842135
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.64508
KMS34	DepMap CRISPR Gene Dependency	1.0	4.0643
SOCS3_DELETION_GDS1254_80_mouse_ES (embryonic stems cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935649
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998103
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62469
ITLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.363
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYB	ENCODE Transcription Factor Targets	1.0	null
K562	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.51465
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JO-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12784616-12711_2025_1028_MOESM2_ESM.xlsx-TableS5-Table_S5_Summary_of_significant_MR_associations_in_blood_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
trifluoperazine-1004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Compound leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
MEPCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44463
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Multinodular goiter	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2904-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_up_VENN-697_elements_included_exclusively_in_HIF1_genes_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
Fetal_Intestine_Large	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.91209
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.17674
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.638
SIN3A	ENCODE Transcription Factor Targets	1.0	null
16728981-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.971245
CRCGN017_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21964
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3373
tolnaftate-1501	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE75976_3_v_9_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary bladder	HPA Tissue Gene Expression Profiles	-1.0	-0.825138
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7447
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
RNASET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35287
TET1	ChEA Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06981
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61086
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4924
Perturb_15270_KO_Bap1_SRP162522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF341	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70018
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.26865
GSE225647_0_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
17483317-TableS5	GeneSigDB Published Gene Signatures	1.0	null
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08184
RAB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04581
Macular Degeneration	dbGAP Gene-Trait Associations	1.0	0.255209
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0113
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54557
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2063
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83114
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE98898_7_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2525
18614019-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
ITPRIPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97507
ARAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68166
Asthma and major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22851
Stevens-Johnson syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.112
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44223
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.174
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54543
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-619	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SLC6A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5789
10-methoxyharmalan-6355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30808
Adrenocortical carcinoma_ACC_TCGA-OR-A5L6-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8419
Perturb_10638_Mut_Cryaa_SRP104440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.74759
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
epiandrosterone-4626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81994
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	4.25102
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19796
Protein kinase 5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE225647_1_v_3_srsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.99217
NPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53963
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23975
F0447-0125-6396	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74301
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.972352
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16463
fludrocortisone-3785	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11802
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2473
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.22406
PDS5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78285
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07179
CCT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91454
etodolac-7246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886527
CLTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36805
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AIFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61421
Takayasu arteritis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.709691
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34312
JAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46492
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87394
ALDH18A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70625
Vasculitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.676
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary pigmented nodular adrenocortical disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
Bone_Marrow-erythroid progenitor	Tabula Sapiens Gene-Cell Associations	1.0	3.08608
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38505
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.28048
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.928311
HG3	DepMap CRISPR Gene Dependency	1.0	5.43404
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80302
Germ tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5665
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-IE-A4EH-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.1676
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27409
COQ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78963
cefazolin-7385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.26992
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54328
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94335
TYMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68373
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95702
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68819
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5661
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02764
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04329
18593951-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L4-A4E5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66221
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50295
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14855
hsa-miR-129-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15029
paroxetine-4378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7754
GNG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16357
Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2844-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22516
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.39513
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.38647
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	-1.0	-1.32817
levothyroxine sodium-1312	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TTLL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31059
CBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2743
H3K4me1_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.028218
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.85545
CTCF	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9708_KO_Nox4_SRP330045	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.83377
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.84062
INTS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03548
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8813
hsa-miR-3680	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958475
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC22A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2363
Lung adenocarcinoma_LUAD_TCGA-62-A470-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12083
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20682
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0341
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.847412
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.901941
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.967731
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nb4	HPA Cell Line Gene Expression Profiles	1.0	1.53924
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91983
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05443
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883825
ZNF740	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15122
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
ECT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3968
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55294
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25123
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30169
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62704
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39246
MOLP2	CCLE Cell Line Gene CNV Profiles	1.0	1.89214
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.80956
practolol-4603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43495
chromosome, telomeric repeat region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64298
NFYA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68629
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96412
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16521
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.311
LNX1	Pathway Commons Protein-Protein Interactions	1.0	null
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Adenomatous polyposis coli domain	InterPro Predicted Protein Domain Annotations	1.0	null
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.44704
ACOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06413
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847385
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4419
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43945
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00988
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47823
KP1N	DepMap CRISPR Gene Dependency	1.0	2.288
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23734
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
UBE2W	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9113
CGAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64727
Perturb_11807_KO_Il33_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.47482
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29064
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.235093
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.93203
FKBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82367
Acute Myeloid Leukemia_LAML_TCGA-AB-2930-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8185
TAL1	ENCODE Transcription Factor Targets	1.0	null
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.528
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YJEFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10445
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A8BN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.584
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.55413
cisapride-3305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33653
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52936
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2964
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11277
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.865
mRNA_DNMT3B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K36me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
BIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05589
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.05027
MKN45	CCLE Cell Line Gene CNV Profiles	1.0	1.55093
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12613
PGLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0606
GATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08335
Pleuropulmonary blastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26355
miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935238
ZGPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27183
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.89617