association	dataset	threshold value	standardized value
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
DISP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28511
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36633
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34562
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TIMM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76127
FJX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3347
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx Heart 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	6.71769
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.0505
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4369
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86142
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1845
GTEx Colon 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	19.6578
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.34542
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
GSE195568_2_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70133
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94926
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90967
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50443
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2249
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29026
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96658
NAPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5844
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59057
GTEx Heart 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	3.19747
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24065
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35271
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0734
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41047
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
APLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03241
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94262
BRCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24036
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2431
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4168
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93787
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3409
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15426
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1144
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7705
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04117
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7391
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49828
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82517
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33935
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7268
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59125
RPL27A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14839
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2618
PHOX2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24729
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
CAPAN-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09547
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35083
MTARC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62119
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7337
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92539
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9134
GSE60217_1_v_9_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sperm principal piece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32968
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0833
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
Pharyngeal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
RNF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15428
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84132
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60769
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50565
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36385
TRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
GTEx Brain 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	6.83506
Sperm midpiece	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.86
TRIP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03414
GTEx Nerve 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	5.67368
GTEx Colon 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	7.23837
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34004
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.834
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51217
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5969
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29381
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42772
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CGREF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92742
phosphatase binding	GO Molecular Function Annotations 2025	1.0	null
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66551
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
GSE88819_1_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WWTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19063
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27094
ANKFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74456
MICAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94554
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
CHKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61857
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3185
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8498
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86564
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12232
UHRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31233
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43279
ETV7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82611
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5481
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10633
PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_2_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57156
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1209
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.395
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1134
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13063
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78691
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.4674
GTEx BloodVessel 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	10.2632
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27094
PPP1R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19082
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91784
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85563
CDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29339
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63673
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51667
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5922
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51731
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50475
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94152
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4795
GTEx Vagina 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.70897
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.767
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx AdiposeTissue 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	5.18057
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19229
vp8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
Skin epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
EEIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80295
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8789
SCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11984
HME1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCDC9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95649
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3224
HSFX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39174
CHST15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03008
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3515
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sperm flagellum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0804
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33232
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.061
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26886
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3508
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42382
UBA52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58113
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7363
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14783
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
Moh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34197
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25131
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0439
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78331
UNC119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45196
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95285
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66329
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1863
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53726
TMEM150A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40961
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48556
MFAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9641
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC7A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38527
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01875
SLC19A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08714
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53057
e1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.374
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71141
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTGES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31393
Cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
DPAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00628
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9757
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33349
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66698
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.32
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.64305
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31476
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54881
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OSBPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33498
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6203
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59776
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8273
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53022
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09703
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86941
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44215
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02575
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29919
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_1-Supplemental_Table_S1_1_Genes_significantly_downregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
Collecting duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.191
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.679
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3738
ARHGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55757
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.296
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02884
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08869
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
SP100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20666
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3562
MARK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58885
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ALS2CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45019
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21689
RIMOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24104
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1207
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
GTEx AdiposeTissue 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	12.819
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
GSE153064,GSE153065_1_v_0_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39447
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
STON1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02822
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74537
GTEx Colon 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	5.64012
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Orthogonal array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8055
Oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.407
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35854
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF700	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08491
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33549
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63713
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5557
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67056
DHX33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4612
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4477
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06865
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DCLRE1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81882
C18orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0916
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1347
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13658
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6493
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1127
GTF3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52393
PHLDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41594
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Lung 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	11.4672
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.853
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.679
DUSP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22732
EIF3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56231
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4394
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69767
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.67848
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.178
GTEx AdiposeTissue 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	7.21394
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11056
ADRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17322
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11030494-media-2.xlsx-ST12-Supplementary_Table_12_Genes_identified_by_MAGMA_as_being_significantly_associated_with_the_internalizing_spectrum_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49393
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55748
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42886
ATF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43921
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.37547
GSE147240_3_v_1_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11476
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51267
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34169
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96463
USP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54086
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26312
Nasopharynx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00667
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9349
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22492
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4089
MPV17L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60451
DOHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2893
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17101
PLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82112
GSE205021_3_v_2_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8B_Het1A-HNF4A_2d_5x_open-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.54851
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54112
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97629
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2731
9+2 motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.565
ABCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45448
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
PMC8554124-DataSheet2.XLSX-4-RORA_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.397
PTGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56898
Ciliary basal body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67609
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spatial memory	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95518
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81151
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21016
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8987
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19037
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26118
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	13.0009
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34067
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29895
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31248
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12937
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13158
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41306
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
KAT6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59639
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34266
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64509
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7474
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
GSE114992,GSE114993_8_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0924
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
B3GNT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44969
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66008
GTEx Lung 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	4.3409
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81153
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15768
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44571
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53535
GTEx Uterus 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	12.4805
C1orf115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76829
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40915
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42023
ZC3H8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02349
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Radial spoke	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.493
TMEM234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94809
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.51
RTKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15073
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HMBOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17134
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02428
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62874
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_17_KD_HEK293-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9386
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53637
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
MA-104 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADCY5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21864
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84727
GTEx Nerve 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	8.57371
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13474
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.346
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9114
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.27656
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47158
GSE221577_2_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21189
DNAAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68526
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69747
TMEM14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64407
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5073
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92675
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0512
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27251
GTEx BloodVessel 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	5.79297
PMC10925000-12885_2024_12075_MOESM2_ESM.pdf-2-JUNB_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2IRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22244
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8655
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63515
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2448
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99918
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
VPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49594
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71635
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3798
ARL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33745
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60941
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
COX6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85818
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67448
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2834
TACC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31252
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4568
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6861
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.235
NR1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71561
PMC10115648-41591_2023_2271_MOESM3_ESM.xlsx-ST18_SMR-Unnamed_3_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21076
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12492
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CCNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46479
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50296
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02901
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47692
CDK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03474
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20942
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26872
MIS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58648
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6125
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95928
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9745835-supp_079195.122_Supplemental_Table_1.xlsx-ADAR-KD-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
UQCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
GTEx AdiposeTissue 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	12.847
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24625
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4769
GAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35274
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35932
KCTD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27519
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.354
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28175
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DHX57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67382
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.575
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32493
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02524
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.639
MYO1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22687
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4676
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38644
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61736
Motile cilium	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6782
GSE111881_0_v_1_znf768_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx Heart 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	3.1135
Plasma membrane bounded cell projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.625
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77503
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1024
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60152
Oviduct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
PTPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04314
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MARVELD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50759
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.6577
DDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77711
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14843
PMC5668942-supp_gr.216721.116_Supplemental_Data_S2.xlsx-Artery_Tibial_IR-TE-SRCAP_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43729
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.54496
PMC10115648-41591_2023_2271_MOESM3_ESM.xlsx-ST18_SMR-SMR_results_for_lipid-trait_gene-lipid_and_gene-trait_associations_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81457
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
VPS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68803
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.14386
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2579
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
PPM1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7115
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43073
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.648
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx BloodVessel 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	25.6111
GSE157635_1_v_0_trem2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15428
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86488
TBC1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36651
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8902
CFLAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26602
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42381
PARP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47767
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28593
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64746
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02904
ISX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87855
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RELB_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.51
VCPIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92985
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDK17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00557
MED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21627
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20519
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86636
ATOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48649
MT-ND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50539
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2274
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08787
USP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59588
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.23184
GSE203308_14_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6991
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5291
Peritubular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73089
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.24
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5944
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.034
SPARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30478
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50799
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
GTEx Pancreas 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	3.28305
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42177
FDXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78136
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18367
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20264
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LCN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99338
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11498
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44868
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1873
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96578
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE127261_1_v_2_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3781
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
BZW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67921
GSE145311_1_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55051
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6013
ARNT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0649
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96832
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23234
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61548
ZFYVE26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.452
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67023
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
MFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41831
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07216
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33817
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45352
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4315
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.826
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91624
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18656
9+2 motile cilium	GO Cellular Component Annotations 2025	1.0	null
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
LIPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50545
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78597
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8963
Catenin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
OTOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34533
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81596
BRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01771
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54713
GSE166767_1_v_2_ctcfl_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38577
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.747
MRPS18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28162
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07313
ACSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5794
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85741
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S18-Table_S18_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-002_4H_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51053
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40043
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14664
sperm flagellum	GO Cellular Component Annotations 2025	1.0	null
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00914
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8547
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41985
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2951
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32325
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_1_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06839
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.4656
PLEKHF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87806
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8037
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.894
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08472
Microtubule organizing center	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56824
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZSWIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48172
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11518656-ADHM-13-0-s002.pdf-40-BAZ2B_BAZ2B	Rummagene Transcription Factor Associations 2026	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.891
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10214
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
MCFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82258
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34945
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47389
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70989
ADAMTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16367
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.842
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20123
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17878
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85571
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8276
SEL1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23035
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06693
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6199
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.299
ACTR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06715
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2481
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.594
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1155
MIS18BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08338
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.115
SHOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15622
ARL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08902
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3082
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72493
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
TDRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86232
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1369
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21507
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11030494-media-2.xlsx-ST12-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79982
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34454
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05563
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32334
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15238
DIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46664
PPP1R10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44004
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.821