association	dataset	threshold value	standardized value
GTEX-R55D-0326-SM-48FES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
t56-vastus-lateralis_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.75262
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10737
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45699
GTEX-U3ZN-0326-SM-3DB86	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93258
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
facit collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.430253
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.882
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6421
mRNA_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280624
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38126
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383744
cell part	GO Cellular Component Annotations 2015	1.0	null
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40024
EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tongue muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
AB-12-PP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347241
Presubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39273
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46198
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217554
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.2208
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75569
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879058
positive regulation of multicellular organismal metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233368
RB-22-TT44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281928
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plastid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.176024
positive regulation of collagen metabolic process	GO Biological Process Annotations 2015	1.0	null
MON	DepMap CRISPR Gene Dependency	1.0	2.81949
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38597
response to growth factor	GO Biological Process Annotations 2015	1.0	null
formation of primary germ layer	GO Biological Process Annotations 2015	1.0	null
DB-18-UF01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268203
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20536
GTEX-S32W-1526-SM-4AD6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851624
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	167.691
proteinaceous extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.638005
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Hypertension	CTD Gene-Disease Associations	1.0	1.26978
BMP signaling pathway	GO Biological Process Annotations 2025	1.0	null
Activin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.38261
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
ACKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31968
organelle subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.124911
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.970092
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3715049__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.0361
collagen fibril organization	GO Biological Process Annotations 2023	1.0	null
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314531
transcription regulatory region dna binding	GO Molecular Function Annotations 2015	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28583
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.769
CDC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15163
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
QB-72-LM87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218202
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933593
cellular response to BMP stimulus	GO Biological Process Annotations 2023	1.0	null
abnormal somite development	MPO Gene-Phenotype Associations	1.0	null
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55886
anatomical structure homeostasis	GO Biological Process Annotations 2015	1.0	null
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02099
CF-48-QD87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236948
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42556
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60591
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38739
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054664
Joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.968
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16651_KD_Fus_SRP179634	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.59443
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.671233
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954294
MAX_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490879
FE-82-WB22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.609664
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.38244
rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PMC11438719-43032_2024_1653_MOESM4_ESM.xlsx-dNKall6orig-dNK_MAF_1_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20536
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.484
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61004
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854584
GSE188869,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
collagen type i trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200328
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6781
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39191
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380055
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65158
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06296
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10137
Enthesopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
Biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07913
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0011-R10B-SM-4E3JT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845806
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.3639
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2726-SM-4B66W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
saliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.641238
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45249
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14845
Fibrodysplasia ossificans progressiva	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.477
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-1426-SM-4KKZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21538
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00154
ABCA1_OE_GDS2303_189_mouse_LDL receptor-deficient livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10067
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392939
homeostatic process	GO Biological Process Annotations 2015	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.50055
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02096
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46343
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	211.788
GSE169590_6_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285469
GTEX-S4Z8-1726-SM-3K2AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33441
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39098
MYOG_myocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36515
abnormal humerus morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2555
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.628904
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40113
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37892
thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.140388
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069196
regulatory region dna binding	GO Molecular Function Annotations 2015	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.615377
GTEX-S4P3-0326-SM-4AD6P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85998
swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387027
leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107231
mesoderm formation	GO Biological Process Annotations 2015	1.0	null
response to organic substance	GO Biological Process Annotations 2015	1.0	null
GSE237040_0_v_3_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-21-VE32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556165
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30909
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418123
MKKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25097
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08678
Intercostal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
TNFRSF10D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66329
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-29-ZD04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21639
regulation of transcription by RNA polymerase II	GO Biological Process Annotations 2025	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969933
TRIM28	ChEA Transcription Factor Targets	1.0	null
FD-79-TC61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20422
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073121
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16075
Weill-Marchesani syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.934707
PMC3577904-pone.0056590.s007.xls-Affected_genes-Table_S3_Significantly_affected_genes_in_MHC-CELF_hearts_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Chondroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TRABD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70291
Fatty Liver	CTD Gene-Disease Associations	1.0	1.7568
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
496100552_PCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0664
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.575616
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408328
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345179
GSE93309_2_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165307_2_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Childhood absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
KCNAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1531
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46256
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46397
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20755
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04921
supramolecular fiber organization	GO Biological Process Annotations 2025	1.0	null
AE-95-UU45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20528
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09678
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	1.95936
ZD-85-ND87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.652081
Tenia tecta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08587
abnormal limb morphology	MPO Gene-Phenotype Associations	1.0	null
PTPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01645
IC-91-IX22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475573
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5289
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_16840_KO_Bcl11b_SRP340294	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Wing bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XUJ4-0326-SM-4BOP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00685
AC-50-FR41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287149
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29581
Somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.097
HB-92-PE54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239097
CAL72	DepMap CRISPR Gene Dependency	1.0	3.71753
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2943
negative regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
YC-45-JD42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.51975
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41639
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6311
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01324
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08805
accessory sex gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254902
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330842
MYOG	ENCODE Transcription Factor Targets	1.0	null
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24857
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55408
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5609
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32127
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205540_2_v_1_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22194
KDM3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14407
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9706
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868801
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13901
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839852
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309713
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0009
SNU410	DepMap CRISPR Gene Dependency	1.0	3.32982
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46586
Edema	CTD Gene-Disease Associations	1.0	1.2437
gingival	GeneRIF Biological Term Annotations	1.0	null
Polytene chromosome band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.934
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64966
BA-39-HG26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354514
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20356
PMC8242083-41467_2021_24064_MOESM4_ESM.txt--HSF1_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313221
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36745
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.33473
ezh2_22267199_heart_lof_mouse_gpl6246_gds4309	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.649063
connective tissue development	GO Biological Process Annotations 2023	1.0	null
positive regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
THO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.811
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.58838
GTEX-S341-1626-SM-3K2B8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93643
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8167
Foot muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.638
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71117
NALM16	DepMap CRISPR Gene Dependency	1.0	2.44381
GSE174406_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CC-50-FK24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265646
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911435
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.202
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.27672
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9512
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41Q-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
SKUT1	DepMap CRISPR Gene Dependency	1.0	5.16344
Extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
COV318	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23195
positive regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1109
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF21-23034159-E13-GONADS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19154
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27863
studies	GeneRIF Biological Term Annotations	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.077
chloroplast thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.927952
DNA-binding transcription activator activity, RNA polymerase II-specific	GO Molecular Function Annotations 2023	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60783
Chondrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.167
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29412
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68033
Thoracic thymus_CT1_cortical thymic epithelial cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GTEX-XBED-1326-SM-4AT4F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
BA-10-WH12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.521261
Perturb_11746_KO_Mek2_SRP321493	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.54359
Hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-S4P3-0626-SM-4AD59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.34451
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60119
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.881151
Infertility, Female	CTD Gene-Disease Associations	1.0	1.15324
FAM117B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73682
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32466
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15528
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83871
Swine testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3196
negative regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
col2a1	GeneRIF Biological Term Annotations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
positive regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21564
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070186
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848249
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6077
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203948
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
microcephaly	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-WFG7-0926-SM-4LMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06215
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07799
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.6755
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13503
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
positive regulation of gastrulation	GO Biological Process Annotations 2015	1.0	null
Uterus-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	1.89226
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170808
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08331
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091183
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.7037
DE-69-QQ25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297611
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.42777
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19258
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
negative regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
Osteoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
positive regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7226
PMC12323057-13148_2025_1945_MOESM2_ESM.xlsx-17-Supplementary_Table_17_Overview_of_number_of_targets_genes_shared_with_THRB_THRB	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05043
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63805
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47373
positive regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
positive regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13269
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072093
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844161
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13134
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.03197
PMC3715049__F1	PFOCR Pathway Figure Associations 2023	1.0	null
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51319
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92804
nor10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93264
Nkx-2.5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
nectary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180378
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38853
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13523_KD_Arid1a_SRP333303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15759
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.839091
Neural arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
Congenital heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072329
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90177
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99089
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52041
NCIH2171	DepMap CRISPR Gene Dependency	1.0	2.71901
bone	GeneRIF Biological Term Annotations	1.0	null
collagen	GeneRIF Biological Term Annotations	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01658
positive regulation of collagen metabolic process	GO Biological Process Annotations 2023	1.0	null
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68763
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.03267
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149124,GSE149128_3_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096457
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
Corn silk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27583
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	1.0	1.3258
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34722
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02477
IC-79-JZ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283993
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.35268
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361527
ebox	GeneRIF Biological Term Annotations	1.0	null
regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390799
RELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13139
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1096
sequence-specific DNA binding	GO Molecular Function Annotations 2023	1.0	null
negative regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
cervical squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381755
abnormal stationary movement	MPO Gene-Phenotype Associations	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073302
abnormal dorsal aorta morphology	MPO Gene-Phenotype Associations	1.0	null
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.46983
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15278
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.20175
Atrophy	CTD Gene-Disease Associations	1.0	1.3682
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279913
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
GSE112358,GSE112359_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329596
abnormal deltoid tuberosity morphology	MPO Gene-Phenotype Associations	1.0	null
AB-25-XU75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323429
Flexor tendon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.276
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074905
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051386
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997312
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.072735
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.738725
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0137
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2011
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61947
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33672
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49341
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20143
PMC5352226-elife-20488-fig4-data5.xls-tfnames-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rh30	HPA Cell Line Gene Expression Profiles	-1.0	-1.03432
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174617
GTEX-QMRM-1726-SM-2S1QG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.849585
496100511_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11411
Inflammation	CTD Gene-Disease Associations	1.0	1.41257
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.69
Mesenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.844
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075964
ZB-33-MZ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.811348
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Sternum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Mesenchymal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.015
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0087
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11492
TAF1	ENCODE Transcription Factor Targets	1.0	null
cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.28616
sertoli cell differentiation	GO Biological Process Annotations 2015	1.0	null
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
RA-42-CM42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332214
GSE157911_1_v_0_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Lung transplant rejection_Trachea_GSE3418	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.07197
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914653
chloroplast thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.256197
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30095
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14919_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93461
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843593
CORO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01372
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02745
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069196
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063326
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347997
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908959
Prostate adenocarcinoma_PRAD_TCGA-J4-A67Q-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-49-OG36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.478906
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.03752
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25922
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.715405
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
NCIH660	CCLE Cell Line Gene CNV Profiles	1.0	1.37296
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880998
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01406
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935701
positive regulation of embryonic development	GO Biological Process Annotations 2015	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18687
Kidney Chromophobe_KICH_TCGA-KN-8426-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08943
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.69491
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
CF-48-QD87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410072
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.933499
Affected pathways in Duchenne muscular dystrophy	WikiPathways Pathways 2024	1.0	null
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.92139
BA-15-VE07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242865
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10018
Tendon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.956
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53993
abnormal vascular development	MPO Gene-Phenotype Associations	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01831
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.583012
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12401
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14949
positive regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2023	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.668
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91526
Perturb_7093_OE_Ppp3cc_SRP310497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Perturb_2948_KD_Hnrnpk_DRP004738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.17158
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of DNA-templated transcription	GO Biological Process Annotations 2025	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30099
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acromicric dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
PMC12802643-mmc10.xlsx-EC2-EC2_Endothelial_subcluster_2_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
HCC1806	DepMap CRISPR Gene Dependency	1.0	5.53793
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14719
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15568
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52824
GSE120413,GSE120447_3_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38037
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.16221
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
E-box binding	GO Molecular Function Annotations 2025	1.0	null
JB-14-ZM03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448993
PMC4923873__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Periodontal ligament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2848
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.30705
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.801
nucleoplasm part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.613742
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2259
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395669
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.277
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0548
GSE136627_2_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05504
Skin-cell of skeletal muscle	Tabula Sapiens Gene-Cell Associations	1.0	0.388362
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19356
RB-55-KL42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212648
TCF12	ENCODE Transcription Factor Targets	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.932
Satellite cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
tlrelated	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27896
BB-87-SF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324904
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2157
nuclear lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.509604
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14775
PMC12464728-HSR2-8-e71283-s008.pdf-380-ZNF780A_ZNF780A	Rummagene Transcription Factor Associations 2026	1.0	null
BHT101	DepMap CRISPR Gene Dependency	1.0	3.41679
SUZ12	ChEA Transcription Factor Targets	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.23584
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587075
Aorta	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.965815
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515753
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.413183
OC-10-FB51_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24491
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.1564
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIPK4	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3069
BA-84-WN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240973
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06162
HCC1937	CCLE Cell Line Gene CNV Profiles	1.0	1.94149
GSE221004_3_v_0_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.354042
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin-nk cell	Tabula Sapiens Gene-Cell Associations	1.0	0.00806687
Cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12321
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48187
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00324
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0484
Cardiofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.646505
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal blood vessel morphology	MPO Gene-Phenotype Associations	1.0	null
BMP signaling pathway	GO Biological Process Annotations 2023	1.0	null
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.863311
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13748
Osteophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
BE-03-XC62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.559033
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.662742
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
positive regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
negative regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.05934
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18866
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
abnormal muscle physiology	MPO Gene-Phenotype Associations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.59226
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879026
PMC4267896__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal long bone morphology	MPO Gene-Phenotype Associations	1.0	null
Primary somatosensory area, nose, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26338
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08868
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25632
DA-27-BW20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371299
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35418
intracellular part	GO Cellular Component Annotations 2015	1.0	null
nucleic acid-templated transcription	GO Biological Process Annotations 2023	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
organic cyclic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.45431
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03992
prostate cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.639214
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083497
FF-28-ES17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.767249
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.567169
SW954	DepMap CRISPR Gene Dependency	1.0	3.58116
PMC7705468__F1	PFOCR Pathway Figure Associations 2024	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386922
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.141277
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312576
Chondrogenic MCT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.285
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41401
chloroplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.222083
mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408592
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5619
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43056
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RWSA-0826-SM-2XCBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53203
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218727_0_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6135
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324659
marrow	GeneRIF Biological Term Annotations	1.0	null
inhibited	GeneRIF Biological Term Annotations	1.0	null
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.118724
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.834289
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8752
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.930411
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989223
endochondral bone morphogenesis	GO Biological Process Annotations 2025	1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18272
abnormal artery morphology	MPO Gene-Phenotype Associations	1.0	null
squamous cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078631
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.493122
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317679
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928834
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410907
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
transcription factor complex	GO Cellular Component Annotations 2015	1.0	null
siha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
heart valve morphogenesis	GO Biological Process Annotations 2015	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sequence-specific DNA binding	GO Molecular Function Annotations 2025	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
nucleobase-containing compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
KYM1	DepMap CRISPR Gene Dependency	1.0	5.29837
Hypobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
tissue homeostasis	GO Biological Process Annotations 2015	1.0	null
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19667
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	3.26517
myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.808968
ZD-18-MI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.975827
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.15948
EFE184	DepMap CRISPR Gene Dependency	1.0	3.58655
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.33059
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64559
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15874
AE-56-SL06_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.972626
GSE144231_4_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-18-UF01_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.651108
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407832
BC-10-OR76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265455
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256189
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00851
BD-69-XG81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396185
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41401
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
Cementum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
GTEX-S3XE-0326-SM-4AD6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0935
tendon development	GO Biological Process Annotations 2015	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.522
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906433
CREM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86729
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01878
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35846
cellular response to mechanical stimulus	GO Biological Process Annotations 2015	1.0	null
AA-48-XT80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260262
GTEX-QEL4-0726-SM-3GIJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52051
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.561396
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vasculature-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	11.7108
Tendon cell_Tendon_Human	CellMarker Gene-Cell Type Associations	1.0	null
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73608
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84845
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128699
Hyperplasia	CTD Gene-Disease Associations	1.0	1.68612
failure of somite differentiation	MPO Gene-Phenotype Associations	1.0	null
HSPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62638
style	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212586
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00345
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64728
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227802
Articular cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Septal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1126-SM-3NMBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04066
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0899
negative regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26628
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884198
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-WY7C-0226-SM-3NB37	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34496
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162505
CCD-8Lu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335918
GI1	DepMap CRISPR Gene Dependency	1.0	2.69204
skeleton phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.809728
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234286
response to bmp	GO Biological Process Annotations 2015	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20017
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49798
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.35493
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13446
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962967
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EF-85-DA07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.64174
cellular nitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MPV17L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00662
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
Perturb_11884_OE_Fra2_SRP099567	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.26449
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13324
biceps brachii	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.354826
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.7124
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
NB-79-SE70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488045
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
PMC9633745-mmc3.xlsx-Table_S2-Up-regulated_in_MSC-2_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02667
AB-80-CK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473969
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54799
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91999
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-35-4123-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-74-RX30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277446
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
DNA-binding transcription factor binding	GO Molecular Function Annotations 2025	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.39897
Acromesomelic dysplasia, Grebe type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19907
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36235
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.554318
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35139
regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
FF-28-ES17_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.475597
Chondrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
JD-87-KA71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41533
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.39558
PDSS2_KO_GDS3454_120_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94878
response to stimulus	GO Biological Process Annotations 2015	1.0	null
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
gastric juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897635
altered righting response	MPO Gene-Phenotype Associations	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CB-32-EI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247686
colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.281868
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452366
KLF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.9231
positive regulation of cellular process	GO Biological Process Annotations 2023	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MS (Multiple Sclerosis)_CNS - Spinal Cord (MMHCC)_GSE842	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68992
type	GeneRIF Biological Term Annotations	1.0	null
Geleophysic dysplasia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47577
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.9427
Stigma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1528
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070312
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.761984
HIPK3	Kinase Library Serine Threonine Kinome Atlas	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
positive regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
PMC7705468__F2	PFOCR Pathway Figure Associations 2024	1.0	null
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.479488
cellular response to organic substance	GO Biological Process Annotations 2015	1.0	null
GSE182680,GSE182683_10_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1547
BMP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
BAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10254
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264097
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51462
Perturb_10180_KO_Atrx_SRP282433	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.69043
S0-EE-Y97N_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250774
TRIM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36486
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01123
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.769
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11835
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955692
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.06803
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.87856
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
NA-16-OJ70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231008
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330234
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47672
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72232
Branchial arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8608
flexor digitorum profundus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.543359
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328025
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0944
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alevin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
DC-78-CM38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203916
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848659
Perturb_9098_KD_SS18_SRP128693	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.06286
Hypertrophy	CTD Gene-Disease Associations	1.0	1.75738
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.03122
GF1B-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33535
NEFM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11093
Lung squamous cell carcinoma_LUSC_TCGA-98-A53B-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74487
negative regulation of programmed cell death	GO Biological Process Annotations 2023	1.0	null
AB-80-CK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.549625
NKX2-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70247
breast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.548517
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065844
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
YE-80-LN04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374503
abnormal tendon morphology	MPO Gene-Phenotype Associations	1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QDT8-0426-SM-32PKZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
16909116-Table2	GeneSigDB Published Gene Signatures	1.0	null
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.85962
egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.444499
BE-17-CS60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480029
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29775
prostate_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.0935
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.6479
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.566223
Mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
ZR7530	CCLE Cell Line Gene CNV Profiles	1.0	2.17987
BE-92-TW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268508
ZNF730	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27287
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
GTEX-WFG8-2326-SM-3GILF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059987
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44318
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372561
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.624881
DNA-binding transcription activator activity, RNA polymerase II-specific	GO Molecular Function Annotations 2025	1.0	null
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82174
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37113
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844931
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15339
SOX9	ChEA Transcription Factor Targets	1.0	null
GSE224311_3_v_0_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.285802
CF-24-KQ98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.622509
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.44616
BL4037 (CORO1A)	NURSA Protein Complexes	1.0	null
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982604
collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.680284
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23634
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.440443
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1934
JHOS4	DepMap CRISPR Gene Dependency	1.0	2.32783
Uterus-immune cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0599253
regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6123
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1528
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400953
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13948
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.68508
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.072
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ID-69-QF93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402213
Lung squamous cell carcinoma_LUSC_TCGA-22-4596-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574416
urinarybladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3094
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378033
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233278
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Attachment cell_Tendon_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.7293
gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378372
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.519798
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chondrocyte differentiation	GO Biological Process Annotations 2015	1.0	null
positive regulation of DNA-templated transcription	GO Biological Process Annotations 2025	1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.699873
ZA-84-ZC97_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.255677
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251827
Perirhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.62286
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064185
Myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.949
Muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.431
Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	3.47096
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39763
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856263
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.56
PMC10879698-mmc1.pdf-4-FOXO4_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27736
PD-11-LM65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29918
DUSP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.466
SRY	ChEA Transcription Factor Targets	1.0	null
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1109
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00811
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.01332
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68783
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830348
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.78322
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.924279
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3462
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.060369
RNA polymerase II transcription regulatory region sequence-specific DNA binding	GO Molecular Function Annotations 2025	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.332
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05433
BE-17-CS60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247334
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1454
BC-61-ZY95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23071
DNA-binding transcription factor binding	GO Molecular Function Annotations 2023	1.0	null
VD-08-TC47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437506
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53215
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5627
4t1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.573616
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52347
bhlh transcription factor binding	GO Molecular Function Annotations 2015	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616183
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05441
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RNF126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37631
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954471
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GS-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34722
regulation of DNA-templated transcription	GO Biological Process Annotations 2023	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Elastic fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973103
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
PMC11409756-13062_2024_533_MOESM1_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_DEGs_regulated_by_ZFP64_through_mRNA-seq_ZFP64	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.627
TCF3	ChEA Transcription Factor Targets	1.0	null
VA-92-QP54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22989
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
gynoecium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347038
ossification	GO Biological Process Annotations 2015	1.0	null
Calcific tendinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.811
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
QE-18-WG07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3224
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12212
Tibialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05306
Adductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.606
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9532
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PMC4404138-pone.0124462.s003.xlsx-Sheet1-Genes_affected_in_the_MHC-CELF_severe_line_MHC-CELF_-10_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06777
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04589
cellular component organization	GO Biological Process Annotations 2015	1.0	null
Human - Lung v1 - L2 - Fibromyocyte	HuBMAP Azimuth Cell Type Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PMC11839199-CPR-58-e13746-s001.docx-4-ARID5A_ARID5A	Rummagene Transcription Factor Associations 2026	1.0	null
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32927
cardiovascular system phenotype	MPO Gene-Phenotype Associations	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.597571
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
response to chemical	GO Biological Process Annotations 2015	1.0	null
replacement ossification	GO Biological Process Annotations 2015	1.0	null
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7002
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GD-07-HO70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.21434
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
adipose-derived stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	2.4398
urinary bladder	HPA Tissue Gene Expression Profiles	-1.0	-0.896263
Campomelic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
Heart septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14401
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TA-19-YA45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.7001
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.06931
Myc-type, basic helix-loop-helix (bHLH) domain	InterPro Predicted Protein Domain Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372525
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074959
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13325_KD_Klf8_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.4564
BCL3	ChEA Transcription Factor Targets	1.0	null
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69825
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38279
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3616
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	194.341
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32198
intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.143855
SIRT4_KO_GDS4823_505_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_9096_KD_KDM2B_SRP128693	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.99763
MG63	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53861
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
BC-74-QN56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293936
hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275094
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
chondrocyte differentiation	GO Biological Process Annotations 2025	1.0	null
GTEX-WHPG-0626-SM-3NMBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.164542
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bHLH transcription factor binding	GO Molecular Function Annotations 2025	1.0	null
Activin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.456
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.421492
Perturb_12208_Mut_TP53_SRP287851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.16262
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43074
tendon development	GO Biological Process Annotations 2025	1.0	null
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18038
Weight Gain	CTD Gene-Disease Associations	1.0	1.47193
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11159
CD1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24327
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414721
Arrector pili muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.27236
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.00513
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
regulation of gastrulation	GO Biological Process Annotations 2015	1.0	null
Gill filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FF-28-ES17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.661173
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15339
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6029
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08147
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.419142
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.07701
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043595
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.013
EWSR1	ChEA Transcription Factor Targets	1.0	null
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.566
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266808
positive regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Peroneal neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468271
impaired somite development	MPO Gene-Phenotype Associations	1.0	null
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15723
FOXP2	ChEA Transcription Factor Targets	1.0	null
sclc21h	HPA Cell Line Gene Expression Profiles	-1.0	-0.857878
PMC4923873__F1	PFOCR Pathway Figure Associations 2024	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cartilage development	GO Biological Process Annotations 2025	1.0	null
SP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.4
Cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.809
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25004
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32871
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.597
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.476173
Tibialis posterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875654
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5535855__F3	PFOCR Pathway Figure Associations 2023	1.0	null
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.65388
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.832038
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
HC-38-KI38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.49563
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61941
positive regulation of cell population proliferation	GO Biological Process Annotations 2023	1.0	null
Perturb_13134_KO_Pnpt1_SRP134850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.8774
GTEX-XYKS-1826-SM-4E3JV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50463
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43644
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61578
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Caudate putamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.121
ROCK_INHIBITION_GDS3944_461_mouse_Forebrain astrocytes - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dactinomycin_mus musculus_gpl6246_gse21233	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10881
PMC5417597-pone.0176679.s006.xlsx-Tumor_MLL_vs_AT1-Unnamed_1_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Scapula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01854
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9979
response to abiotic stimulus	GO Biological Process Annotations 2015	1.0	null
JB-23-ZE86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237124
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SB-28-EJ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247757
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_11828_KO_Ptpdc1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74176
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228209
Foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
plastid thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.251839
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
PMC5789791__F1	PFOCR Pathway Figure Associations 2024	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.768801
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
AF-11-IL39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442591
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
prostate gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.635167
positive regulation of biosynthetic process	GO Biological Process Annotations 2025	1.0	null
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16618
abnormal artery development	MPO Gene-Phenotype Associations	1.0	null
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.65345
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999858
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271855
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10057
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289493
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77501
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13269
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90566
BB-86-BE39_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530545
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ocellus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
regulation of cell death	GO Biological Process Annotations 2015	1.0	null
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81619
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878591
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
transforming growth factor beta receptor superfamily signaling pathway	GO Biological Process Annotations 2025	1.0	null
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465297
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.92539
positive regulation of gastrulation	GO Biological Process Annotations 2023	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43531
chloroplast stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.29623
CC-09-YG11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200595
Palpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21875
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.64852
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Unnamed_2_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987894
GTEX-Q2AH-0326-SM-48U1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65836
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68929
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01429
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.713369
Anomalous left coronary artery from the pulmonary artery	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943106
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mesoderm morphogenesis	GO Biological Process Annotations 2023	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64784
Human - Lung v1 - L1 - Fibromyocyte	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11933697-41467_2025_58216_MOESM9_ESM.xlsx-SD7_C_R_NS1_Med_ATF3_DEG-symbol_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33919
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41195
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-639-ENSG00000181135_ZNF707	Rummagene Transcription Factor Associations 2026	1.0	null
Tendinitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.018
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47137
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32516
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.8276
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.09914
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.19802
Cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.329
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0998
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25273
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_nuc-DEGs_for_hnRNPK_KD_Nuclear_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CF-42-OS28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354809
transcription cis-regulatory region binding	GO Molecular Function Annotations 2023	1.0	null
KA-72-WY22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495994
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17336
Periodontal ligament cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33961
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.50055
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.40677
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055813
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92491
PA-25-OV46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313117
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4128
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056383
CAKI1	DepMap CRISPR Gene Dependency	1.0	4.09208
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14511
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44982
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889574
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.527054
NA-29-UI75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280661
nucleus	GO Cellular Component Annotations 2025	1.0	null
Aiolos_NULL MUTATION_GDS3473_572_mouse_Bone marrow pre-BII cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13987
microcephaly	IMPC Knockout Mouse Phenotypes	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.539257
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.06116
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.5644
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03077
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.648029
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CB-88-LG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290651
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6016-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12206_KO_TP53_SRP287851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.39536
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transcription factor complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
sox9related	GeneRIF Biological Term Annotations	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH82	DepMap CRISPR Gene Dependency	1.0	2.77677
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB-33-ZP53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244733
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07534
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U251MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74492
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.909692
GB2	DepMap CRISPR Gene Dependency	1.0	3.66796
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928776
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE3583	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.7676
MC-51-BT07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.557891
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57433
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04752
protein heterodimerization activity	GO Molecular Function Annotations 2015	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.759914
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of cell death	GO Biological Process Annotations 2015	1.0	null
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704113
AD-30-VB23_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216918
Seta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
Perturb_16698_KO_83F24Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.15785
Fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062613
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G1_REST-Dataset_S5_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.623
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
WC-54-BJ14_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212834
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27448
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412794
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00324
nucleus	GO Cellular Component Annotations 2015	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00447
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049213
colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.105316
GTEX-RUSQ-0926-SM-47JWU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.36933
AD-51-LE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257593
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.913566
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4267896__F3	PFOCR Pathway Figure Associations 2023	1.0	null
PHYHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22949
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04135
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.316452
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10175
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.44
Myofibroblast_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
positive regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2025	1.0	null
heterocycle biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of collagen biosynthetic process	GO Biological Process Annotations 2025	1.0	null
collagen fibril organization	GO Biological Process Annotations 2025	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.960371
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07927
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
abnormal limb long bone morphology	MPO Gene-Phenotype Associations	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32038
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68503
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77453
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79731
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387781
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900144
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5799
anchoring collagen complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.177154
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88973
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432722
Ventricular septal defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
CC-50-FK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403858
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239391
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.79622
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08312
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205713
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03666
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.650439
FLO1	DepMap CRISPR Gene Dependency	1.0	4.07199
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324623
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53877
plastoglobule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.666827
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38629
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.971982
cellular response to external stimulus	GO Biological Process Annotations 2015	1.0	null
positive regulation of transcription by RNA polymerase II	GO Biological Process Annotations 2023	1.0	null
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22184
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
S0-EE-YEKU_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322012
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
colon adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169091
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82951
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16379
GSE169590_0_v_1_rptor_human	RummaGEO Gene Perturbation Signatures	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212426
ZFP36L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96754
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Large_Intestine-intestinal crypt stem cell of large intestine	Tabula Sapiens Gene-Cell Associations	1.0	0.00806687
S0-EE-YMWJ_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262985
e47	GeneRIF Biological Term Annotations	1.0	null
Perturb_1287_KO_Pank1/Pank2_SRP194974	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.91758
nuclear body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.845614
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.351
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55833
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52824
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40299
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nymph	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873981
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15874
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-97-ZV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276858
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063782
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077365
GTEX-X15G-0526-SM-3NMB7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.95478
Tendon sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36226
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PMC8497824-Table_4.xlsx-Stage_4_EOMES_vs_Ctrl-Unnamed_1_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1883
hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048726
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251509
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4118
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222011
AF-67-LZ82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.283333
abnormal tail movements	MPO Gene-Phenotype Associations	1.0	null
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Supplementary_Table_7_Transcription_factors_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279598
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
breast adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.505102
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.503
Plantar fascial fibromatosis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
skin_5f	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212086
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47M-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-1626-SM-3K2AJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01317
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
Intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.957722
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
RZZ complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.855319
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01429
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.789
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.859679
KE-41-JG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272864
Sensillum trichodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28621
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.381773
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.372749
photosynthetic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.134322
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.133563
GSE86507,GSE86509_3_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055261
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.635572
HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mesoderm formation	GO Biological Process Annotations 2025	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941502
abnormal cardiovascular system morphology	MPO Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04177
PMC8481886-Table_1.xlsx-A_subsets-fetal_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.20068
GSE242290_1_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412627
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29023
gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181792
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33649
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07357
KB-92-MK13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236413
ROS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.156718
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274439
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990968
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C4I	DepMap CRISPR Gene Dependency	1.0	2.55641
Memory Disorders	CTD Gene-Disease Associations	1.0	1.10665
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11722
GTEX-XAJ8-0226-SM-4GIB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
abnormal tail morphology	MPO Gene-Phenotype Associations	1.0	null
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05418
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22587
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5287
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73028
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.48322
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5989
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884058
Poisoning	CTD Gene-Disease Associations	1.0	1.07589
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46674
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
GA-94-MC54_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.322777
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936457
regulation of gastrulation	GO Biological Process Annotations 2025	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09671
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37936
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06296
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45333
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885943
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86744
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06296
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.697
adipose-derived stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.338
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.88564
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13157
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-XBED-1126-SM-48TCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28323
neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.188905
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33828
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065196
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868801
extracellular matrix organization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66366
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31877
SAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00531
regulation of programmed cell death	GO Biological Process Annotations 2015	1.0	null
Femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.421148
breast cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512171
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107866
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.085
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.350835
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202987
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
eosinophilia-myalgia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.2018
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16833
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048337
choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.199793
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43531
cellular response to abiotic stimulus	GO Biological Process Annotations 2015	1.0	null
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222484
e-box binding	GO Molecular Function Annotations 2015	1.0	null
SPATA24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15311
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.089207
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.28
abnormal cardiovascular development	MPO Gene-Phenotype Associations	1.0	null
subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4576
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261782
MKN1	CCLE Cell Line Gene CNV Profiles	1.0	1.33362
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48361
SW1116	DepMap CRISPR Gene Dependency	1.0	3.38501
RASL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97099
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54878
protein complex	GO Cellular Component Annotations 2015	1.0	null
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
NCIH2081	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61079
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50619
thyroid	GTEx Tissue Gene Expression Profiles	1.0	1.88002
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21409
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.765504
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
AA-86-YV75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460389
PMC5578490-pgen.1006879.s017.xlsx-Top_ETV1_downregulated_genes-Gene_Symbol_ETV1	Rummagene Transcription Factor Associations 2026	1.0	null
thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135455
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.655897
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
Hepatic primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452897
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381003
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AD-51-SS86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.336315
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04637
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.5858
primary	GeneRIF Biological Term Annotations	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824981
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18556
PMC7705468__F1	PFOCR Pathway Figure Associations 2023	1.0	null
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.966
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
IZ in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03682
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.61037
enzyme linked receptor protein signaling pathway	GO Biological Process Annotations 2015	1.0	null
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.5208
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3765
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21897
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Collagen network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.945821
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23766
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15723
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of collagen metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LD-39-FL02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.865309
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-X88G-0226-SM-4GIE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
EC-98-KI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311235
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988191
transcription cis-regulatory region binding	GO Molecular Function Annotations 2025	1.0	null
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
RAB3A_KO_GDS2482_706_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69031
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE191110_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.443313
SIRT4_KO_GSE56321_391_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054251
Tail muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.37981
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81527
EE-02-BO83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37614
SA-03-IQ14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271315
response to transforming growth factor beta	GO Biological Process Annotations 2015	1.0	null
Tenocyte_Tendon_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
negative regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45715
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26495
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5823
Exostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
abnormal tail movements	MGI Mouse Phenotype Associations 2023	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085755
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86918
SUP-B15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44785
Ceratobranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.058
cell-substrate adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.134571
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10697
HD-51-KD29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454568
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12239
BB-79-AG41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261507
PODXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14115
S0-EE-YFM9_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.575918
AA-56-QO38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204643
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07371
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.928
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.386783
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.55353
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1707
Lateral entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14668
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01569
Myosin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.734
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65621
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27298
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22685
GSE114992,GSE114993_0_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JO-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12136_KO_Dlx2_SRP339959	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.8402
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.6803
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29175
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292283
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Venous endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
GTEX-WFG7-2426-SM-3GIL2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
BB-49-OQ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249112
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.584763
promoter	GeneRIF Biological Term Annotations	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415053
CA-66-YB17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330758
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.999812
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.088251
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YC-45-JD42_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515828
FC-35-BX82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375498
nucleoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
regulation of multicellular organismal metabolic process	GO Biological Process Annotations 2015	1.0	null
Intermediate muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.221
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27166
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46012
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970076
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	4.93662
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.88562
GTEX-PWCY-1926-SM-3NB25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.221327
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51272
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-T8EM-1126-SM-3DB7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.285316
abnormal forelimb stylopod morphology	MPO Gene-Phenotype Associations	1.0	null
DNA-templated transcription	GO Biological Process Annotations 2025	1.0	null
regulation of anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35647
AC-83-LN99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.573317
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65244
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43696
CB-87-RB49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232615
OB-78-PA58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.382331
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39763
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_12523_KD_Linc00673_SRP212104	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15514
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67999
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-63-LW25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.446832
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20543
S117	DepMap CRISPR Gene Dependency	1.0	3.7143
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049178
positive regulation of RNA biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
MAPK8IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51938
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74773
trypanosomoid form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138457
CB-24-FA25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14768
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33538
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
GB-64-HC34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214858
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16388
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ligament	GeneRIF Biological Term Annotations	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC8819183__F3	PFOCR Pathway Figure Associations 2024	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22997
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01951
FOXP2	ENCODE Transcription Factor Targets	1.0	null
fibro-adipogenic progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892554
AD-06-OB47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338381
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292447
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.821921
Perturb_13089_KO_Trp53_ERP108431	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4858
transcriptional	GeneRIF Biological Term Annotations	1.0	null
transcription factor binding	GO Molecular Function Annotations 2015	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86001
Myositis ossificans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26471
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072985
Medial entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.5238
DC-31-WP64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288828
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.7762
ID-70-SM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244861
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05946
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23955
GTEX-S4Z8-0326-SM-3K2AU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20655
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33441
abnormal motor coordination/ balance	MPO Gene-Phenotype Associations	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.36933
abnormal tail morphology	MGI Mouse Phenotype Associations 2023	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.293866
periodontal	GeneRIF Biological Term Annotations	1.0	null
GTEX-WEY5-1926-SM-3GIL8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
egg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214765
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97707
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054175
YUHOIN0650	DepMap CRISPR Gene Dependency	1.0	4.65404
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.042
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4681
ZNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77513
cellular process	GO Biological Process Annotations 2015	1.0	null
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
skin_5e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
Pelvic fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35649
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00979
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121626
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445187
CREB1	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A895-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84918
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10595
cellular response to chemical stimulus	GO Biological Process Annotations 2015	1.0	null
BE-31-XV38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447047
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93251
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345558
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52618
positive regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZN-0526-SM-4DXTH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980807
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514469
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
GSE228894_0_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
HA-17-MS45_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.678416
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721577
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXC1_FOXC1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45603
GSE206870,GSE206872_3_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of collagen biosynthetic process	GO Biological Process Annotations 2015	1.0	null
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92815
endochondral bone morphogenesis	GO Biological Process Annotations 2023	1.0	null
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.56787
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.016703
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36462
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14577
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.589635
DNA binding	GO Molecular Function Annotations 2023	1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68003
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.389106
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35983
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.915278
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26471
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.202946
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6597
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAPBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31722
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220005
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
Interventricular septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.585523
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T6MO-0626-SM-4DM6P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
E2A_KO_GSE43224_679_mouse_DN2 cells from WT and E2A-deficient murine fetal thymi	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_820_OE_Rspo1_SRP325709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072702
BE-31-XV38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241048
AB-85-YK41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.600147
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98568
fat_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
C2CD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26402
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81338
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.901987
GSE157960_2_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-31-RM40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239244
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
IC-05-AW29_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228747
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12799
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32965
Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12532
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
endochondral ossification	GO Biological Process Annotations 2015	1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE179880_8_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.536594
RD-92-QT24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417071
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13194
H3K36me3_splenic B cell_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Weight Loss	CTD Gene-Disease Associations	1.0	1.43727
GTEX-XBED-0926-SM-48TCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
SIRT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18922
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38807
GTEX-XXEK-1326-SM-4BRV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.063
DD-26-VR55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361896
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.887133
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44316
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06917
ZA-63-AC60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321824
GA-77-MH38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.47578
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00305
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15971
AC-92-HS43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307952
transmembrane receptor protein serine/threonine kinase signaling pathway	GO Biological Process Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC8403114__F2	PFOCR Pathway Figure Associations 2024	1.0	null
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25708
EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75018
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MNAT1_Deficiency - Ablation_GDS2561_690_mouse_Heart - 4 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20289
XD-08-ZW85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451952
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78797
thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.43696
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34567
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420741
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
TCF21	ChEA Transcription Factor Targets	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18687
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07464
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27953
transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2543
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.072003
SEC62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14138
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.76078
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.303296
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6514
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9041
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PPARD_PPARD	Rummagene Transcription Factor Associations 2026	1.0	null
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215534
regulation of gene expression	GO Biological Process Annotations 2025	1.0	null
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51G-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cell population proliferation	GO Biological Process Annotations 2025	1.0	null
DA-10-VU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.29676
Heart valve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
GSE196540,GSE196542_4_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11012
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46637
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940958
Flexor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7451
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
TCF3	ENCODE Transcription Factor Targets	1.0	null
striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.216126
transmembrane receptor protein serine/threonine kinase signaling pathway	GO Biological Process Annotations 2015	1.0	null
SLC8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5781
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868801
positive regulation of multicellular organismal process	GO Biological Process Annotations 2023	1.0	null
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.082
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.675765
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488647
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1452
GTEX-XUZC-1126-SM-4BOPZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
collagen type ii trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.190495
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12529
ventral posterior medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.940146
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.09892
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1635
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10779
Labial palp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71861
negative regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22317
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.981
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276834
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.598467
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056382
GSE242290_1_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6D_mageckTFkoscreen_with_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844931
PMC4563693__F7	PFOCR Pathway Figure Associations 2023	1.0	null
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73028
mature	GeneRIF Biological Term Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PACADD119	DepMap CRISPR Gene Dependency	1.0	2.09329
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
anatomical structure formation involved in morphogenesis	GO Biological Process Annotations 2015	1.0	null
Amnion epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594805
LU99	CCLE Cell Line Gene CNV Profiles	1.0	1.65861
PMC3577904-pone.0056590.s008.xls-Comparison_to_SR_protein_KOs-Table_S4_Comparison_of_genes_affected_in_MHC-CELF_hearts_with_microarray_data_sets_from_cardiac-specific_SRSF1_and_SRSF2_knockout_models_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
endomyocardial fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.981794
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868801
EGI1	DepMap CRISPR Gene Dependency	1.0	2.00733
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.41484
abnormal skeleton development	MPO Gene-Phenotype Associations	1.0	null
ANKRD65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10665
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
Ovary	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.833669
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC4563693__F7	PFOCR Pathway Figure Associations 2024	1.0	null
AA-11-RO46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.442276
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75191
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04963
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39356
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12888
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993145
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23588
abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111981
HC-74-FM38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.503527
abnormal tendon morphology	MGI Mouse Phenotype Associations 2023	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1386
glucose	GeneRIF Biological Term Annotations	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262645
CSGALNACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34537
positive regulation of developmental process	GO Biological Process Annotations 2023	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
T3M3	DepMap CRISPR Gene Dependency	1.0	2.14806
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03353
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47698
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
BV173	CCLE Cell Line Gene CNV Profiles	1.0	1.98697
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891231
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314046
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.619086
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bmp signaling pathway	GO Biological Process Annotations 2015	1.0	null
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39499
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	189.545
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.9455
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2364
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062365
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18034
E2A_KO_GDS5084_401_mouse_DN2 thymocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE131798,GSE131804_1_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58447
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
BB-51-ML99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372069
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
negative regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61939
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.729693
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00589
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952326
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73387
MYOD1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.38896
Amnion epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
negative regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
FOSL1	ENCODE Transcription Factor Targets	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41328
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S7-HSF1-Neigbhors-HSF1_Neighbors_hg38_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal skeleton physiology	MPO Gene-Phenotype Associations	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31759
protozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086742
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35647
positive regulation of DNA-templated transcription	GO Biological Process Annotations 2023	1.0	null
gene expression	GO Biological Process Annotations 2025	1.0	null
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453817
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069444
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05522
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6C_mageckTFkoscreen_wo_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
proteoglycans	GeneRIF Biological Term Annotations	1.0	null
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.48048
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02308
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597638
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.25531
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.503912
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232686
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.3607
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32335
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
IRS1_KO_GDS1219_303_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mcf-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374618
TD-40-ZR64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474892
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE96641_1_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCCSUP	DepMap CRISPR Gene Dependency	1.0	2.2995
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3922
SMU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5462
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.396
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305512
C1QTNF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11693
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27953
FF-61-PA27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291576
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064413
deltoid tuberosity development	GO Biological Process Annotations 2015	1.0	null
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44839
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PX-01A-51R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-68-KG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241408
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cell population proliferation	GO Biological Process Annotations 2023	1.0	null
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35877
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998035
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46031
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314046
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17546
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.73009
AC-36-FB52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219041
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.094097
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395751
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.1035
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.933644
chloroplast part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.129025
ct-26 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.700262
cell lysate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23762
MCC13	DepMap CRISPR Gene Dependency	1.0	5.7406
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.843458
Learning Disorders	CTD Gene-Disease Associations	1.0	1.57877
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52379
OVISE	DepMap CRISPR Gene Dependency	1.0	2.42343
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.16186
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33246
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60952
absent somites	MGI Mouse Phenotype Associations 2023	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.98011
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98535
BB-74-RX30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.595259
EIF4G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41155
absent deltoid tuberosity	MPO Gene-Phenotype Associations	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45083
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08486
regulation of multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.397513
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63362
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57895
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064436
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.772759
Thymus	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.48253
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16319
Leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.816
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323095
impaired righting response	MPO Gene-Phenotype Associations	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47733
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871168
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34387
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03616
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
cell-substrate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123717
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.578544
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.301083
E-box binding	GO Molecular Function Annotations 2023	1.0	null
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174881
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.318407
fibroblasts	GeneRIF Biological Term Annotations	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.497337
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36658
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.36971
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
fibrillar collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.339639
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.20988
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840817
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33775
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844126
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378578
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
NCIH1975	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49126
PMC8140076-41467_2021_23294_MOESM3_ESM.xlsx-Skeletal_Muscle_Somite-PAX3_PAX3	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45492
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40513
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00642
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.595255
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.724055
cellular response to BMP stimulus	GO Biological Process Annotations 2025	1.0	null
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.714249
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20757
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69687
SIRT4_KO_GDS4823_30_mouse_hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cartilage development	GO Biological Process Annotations 2025	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.119
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57632
Mammary Neoplasms, Animal	CTD Gene-Disease Associations	1.0	1.23962
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03238
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
embryonic skeletal system development	GO Biological Process Annotations 2015	1.0	null
impaired righting response	MGI Mouse Phenotype Associations 2023	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31779
Tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
POLR3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29345
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17955
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.92474
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74837
dna binding	GO Molecular Function Annotations 2015	1.0	null
eosinophilia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.281868
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13451
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.822023
brachyolmia-amelogenesis imperfecta syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
preweaning lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278433
E2A_Deficiency_GDS5084_271_mouse_DN2 thymocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
regulation of embryonic development	GO Biological Process Annotations 2015	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052698
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353852
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35714
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.02464
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.46409
thylakoid part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131835
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433803
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.437751
CB-02-XL81_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09048
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.42562
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HC-92-HE59_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.39194
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15670_KD_Sf3a1_SRP043160	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.42658
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8938
DA-66-OE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284847
RCHACV	DepMap CRISPR Gene Dependency	1.0	2.09844
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11383
AD-55-WK61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252665
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NF-21-HQ00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304155
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07839
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33621
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55221
Head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
Tibialis anterior	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
Mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.01162
TTC549	DepMap CRISPR Gene Dependency	1.0	3.21653
FOXP2-23625967-PFSK-1 AND SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
AA-62-JP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263399
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NMB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254329
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66335
SRY-22984422-TESTIS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
Coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
496100501_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44099
mesenchymal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.767783
GTEX-S32W-1626-SM-4AD6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03953
k562	HPA Cell Line Gene Expression Profiles	-1.0	-0.848523
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1109
Anal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
Acute Myeloid Leukemia_LAML_TCGA-AB-2866-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JE-04-LS32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518205
HIPK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.122
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04328
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14903
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
chronic lymphocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.176757
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supramolecular fiber organization	GO Biological Process Annotations 2023	1.0	null
abnormal tendon stiffness	MPO Gene-Phenotype Associations	1.0	null
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
tendon cell differentiation	GO Biological Process Annotations 2025	1.0	null
Muscle stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.333
carpel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348889
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27617
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70559
Extraocular muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
H2AC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6528
abnormal angiogenesis	MPO Gene-Phenotype Associations	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.14263
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20396
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-51-WE27_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339194
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
KC-26-JQ92_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341068
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041693
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38445
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09842
17660535-TableS4b	GeneSigDB Published Gene Signatures	1.0	null
mesoderm morphogenesis	GO Biological Process Annotations 2025	1.0	null
regulation of multicellular organismal development	GO Biological Process Annotations 2015	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06576
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.650874
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93845
positive regulation of transcription from rna polymerase ii promoter	GO Biological Process Annotations 2015	1.0	null
U343	DepMap CRISPR Gene Dependency	1.0	4.36697
Male Urogenital Diseases	CTD Gene-Disease Associations	1.0	1.06987
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463025
Tenascin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.343
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416195
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
2313287	CCLE Cell Line Gene CNV Profiles	1.0	1.42856
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314046
Fetal Death	CTD Gene-Disease Associations	1.0	1.16269
KIF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74046
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02033
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32253
AB-97-BI36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38189
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9245_KO_Lin28a_SRP300815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98995
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25214
Genital Diseases, Male	CTD Gene-Disease Associations	1.0	1.29626
syndactyly	MGI Mouse Phenotype Associations 2023	1.0	null
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.395193
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890991
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE185519_4_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33386
regulation of transcription by RNA polymerase II	GO Biological Process Annotations 2023	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03462
PMC9424213-41467_2022_32537_MOESM5_ESM.xlsx-HeLa_IER3-AS1sh_DEGs-DEGs_in_HeLa_IER3-AS1sh_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868801
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UHO1	DepMap CRISPR Gene Dependency	1.0	2.68304
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNA polymerase II cis-regulatory region sequence-specific DNA binding	GO Molecular Function Annotations 2023	1.0	null
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6784
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulating	GeneRIF Biological Term Annotations	1.0	null
epithelial cell differentiation	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623057
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94223
endochondral ossification	GO Biological Process Annotations 2025	1.0	null
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851749
somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30568
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00154
Fascia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.638
caudal group of intralaminar nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16336
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073969
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GGPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27174
honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218613
Laterodorsal tegmental nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
identify	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GA-59-RW04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626785
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K36me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68449
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
rectum_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
PMC11022503__F8	PFOCR Pathway Figure Associations 2024	1.0	null
abnormal tendon stiffness	MGI Mouse Phenotype Associations 2023	1.0	null
PMC5535855__F3	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18687
Homomeric SMAD protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.073
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30417
Duckembryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
JC-02-ZR15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314287
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055966
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79533
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.78143
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.23814
Craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.818
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48691
Ubiquinone biosynthesis complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.011
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84069
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Polytene chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.054
DNAJB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21288
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1432
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12892
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tibial cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.879512
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18621
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Cardiac tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.3115
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02025
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5482_KD_Ctnnb1_SRP130920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.05874
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0564
BC-43-PD20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211676
Preosteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01808
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.19402
positive regulation of cartilage development	GO Biological Process Annotations 2015	1.0	null
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.44748
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
DB-18-UF01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323588
GTEX-RM2N-0526-SM-2TF4N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02611
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.37087
FA-88-II68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20829
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37217
regulation of cartilage development	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Sarcoma_SARC_TCGA-MB-A8JL-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5242
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19517
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BF-02-AC35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250349
diethylstilbestrol_mus musculus_gpl81_gse1839	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832591
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951398
perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327896
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493842
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CB-02-XL81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35229
AC-21-IE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290476
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868872
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37784
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09412
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045613
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RIMKLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58842
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208634
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.04978
AB-85-JR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298847
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
FA-89-PW29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296645
Neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.762
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71277
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00966
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
cell differentiation	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
negative regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.77322
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.179459
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-01-FB85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.522137
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47226
response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
GTEX-RU1J-0526-SM-46MUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842787
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840845
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067067
M059K	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40549
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3188
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	206.169
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD-13-QZ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441317
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91053
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.512957
plastid part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123018
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2913
connective tissue development	GO Biological Process Annotations 2025	1.0	null
Muscle-tendon cell	Tabula Sapiens Gene-Cell Associations	1.0	0.820516
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889556
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09971
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.0979
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85328
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44775
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59107
regulation of apoptotic process	GO Biological Process Annotations 2015	1.0	null
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045957
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318186
FC-85-OX77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.39239
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41224
Perturb_17433_KO_Il2ra_SRP167045	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.18854
absent deltoid tuberosity	MGI Mouse Phenotype Associations 2023	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30481
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04235
GSE74251_0_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.847
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.94867
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
system development	GO Biological Process Annotations 2015	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AF-83-BX08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.690757
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266757
connective tissue development	GO Biological Process Annotations 2015	1.0	null
Perturb_9097_KD_KDM2B_SRP128693	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.03194
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.902519
GTEX-XV7Q-0326-SM-4BRVM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02224
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208113
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18437
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.15136
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.577514
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19726
AA-86-YV75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371673
plastid thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.927952
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M040416	DepMap CRISPR Gene Dependency	1.0	2.08755
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242764
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03906
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tendon development	GO Biological Process Annotations 2023	1.0	null
abnormal postural reflex	MPO Gene-Phenotype Associations	1.0	null
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1664
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18415
ZC3H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50421
BL41	CCLE Cell Line Gene CNV Profiles	1.0	1.40604
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60072
Tendon cell_Skeletal muscle_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
negative regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
CLK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.422108
nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190427
forelimb muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264011
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.19815
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501965
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.851749
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.822
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896856
PRDM16_DEPLETION_GDS4021_460_mouse_WAT - white adipose tissue (stromal-vascular cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
regulation of collagen biosynthetic process	GO Biological Process Annotations 2023	1.0	null
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073537
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01457
GTEX-T6MO-0226-SM-32QOL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26275
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	1.50179
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363329
9505BIK	DepMap CRISPR Gene Dependency	1.0	2.39585
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69728
MMAC	DepMap CRISPR Gene Dependency	1.0	4.00263
Nucleus pulposus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.242
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46451
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02539
GTEX-X638-0226-SM-47JZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
histone locus body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.56959
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7732
Temporomandibular joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.503912
Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
95T1000	DepMap CRISPR Gene Dependency	1.0	2.55383
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CC-03-PW00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.215356
differentiation	GeneRIF Biological Term Annotations	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09862
Chromatin	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439537
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11516
Cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
BGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79557
extracellular matrix organization	GO Biological Process Annotations 2025	1.0	null
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67584
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EA-17-BY69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288038
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.4444
tendon cell differentiation	GO Biological Process Annotations 2023	1.0	null
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3174
TCF3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441125
Neoplasms	CTD Gene-Disease Associations	1.0	1.02151
Gastrocnemius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32936
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.833642
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.810603
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35782
PMC12727774-41467_2025_66704_MOESM1_ESM.pdf-11-ZNF384_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.579071
Meniscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8254
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117342
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
dilated dorsal aorta	MGI Mouse Phenotype Associations 2023	1.0	null
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287891
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899983
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
SA-32-CC58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.763139
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5977-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00366
RNA polymerase II cis-regulatory region sequence-specific DNA binding	GO Molecular Function Annotations 2025	1.0	null
tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.212627
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06617
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.630718
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
BE-49-XN43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623855
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	109.389
Kidney Chromophobe_KICH_TCGA-KO-8414-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24681
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.342602
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324546
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.08764
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7429
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26078
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
regulation of apoptotic process	GO Biological Process Annotations 2025	1.0	null
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65994
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18866
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.911
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79556
CCD-25Lu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87105
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81871
GTEx Esophagus 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.9089
Perturb_5760_KO_C9orf72/Tmem173_SRP266242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58515
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.49895
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83857
Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9426
muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.283663
Perturb_14658_KO_Kras_SRP252137	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.87898
AA-52-JS03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358882
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8895
breast cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160325
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68198
Perturb_2125_KO_AMBRA1_SRP288295	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.53202
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08946
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K2-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906505
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30721
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12524_KD_Linc00673_SRP212104	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.535
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.19345
signal transduction	GO Biological Process Annotations 2015	1.0	null
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.459354
tissue development	GO Biological Process Annotations 2015	1.0	null
dilated dorsal aorta	MPO Gene-Phenotype Associations	1.0	null
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
JC-76-VX29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256411
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81032
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34395
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	2.06575
DD-43-WW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445788
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313092
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2883
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AASDHPPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5397
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13868
positive regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Abductor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203599
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071844
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24337
PF-59-CY33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.23576
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18695
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
positive regulation of collagen biosynthetic process	GO Biological Process Annotations 2023	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Synovial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04602
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16713_KO_Prkab1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.89442
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51527
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79085
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Spermatheca	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03306
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31389
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63645
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
HSSCH2	DepMap CRISPR Gene Dependency	1.0	2.47304
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.27813
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03049
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41924
AA-30-BE85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269002
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58045
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52389
chondrocyte differentiation	GO Biological Process Annotations 2023	1.0	null
PHGDH_KO_GDS2874_125_mouse_embryonic head tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04683
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840664
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0526-SM-4GIAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827802
Knee	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
LADD syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.783
abnormal skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-O5YT-0726-SM-3MJHA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5346
leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.221793
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.0455
NCAPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99011
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0273
capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.71042
Corpus cavernosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HD-19-IW09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433821
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58032
positive regulation of macromolecule metabolic process	GO Biological Process Annotations 2023	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.583001
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Wrc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735693
regulation of gastrulation	GO Biological Process Annotations 2023	1.0	null
TGW	DepMap CRISPR Gene Dependency	1.0	2.89782
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.62811
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21511
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324677
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07552
serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371619
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07478
GTEX-XBED-0126-SM-47JY7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880776
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33733
pyridoxine-dependent epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
Mesenchymal stromal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844931
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11572
BE-71-AV63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.900123
extracellular structure organization	GO Biological Process Annotations 2015	1.0	null
MD-49-BL92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217274
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular response to growth factor stimulus	GO Biological Process Annotations 2015	1.0	null
skeletal muscle cell differentiation	GO Biological Process Annotations 2015	1.0	null
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.126
XB-53-OZ95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.814707
DMRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63606
GTEX-SNOS-1426-SM-32PLY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE80222_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2175
anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0936
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85671
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.29508
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.395
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.709
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27896
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02971
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30721
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1109
GTEX-XGQ4-2426-SM-4AT55	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
LE-81-PG11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211955
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218814_1_v_0_suv39h1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.05163
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355564
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5305
BD-01-RI07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.652267
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834991
tendon cell differentiation	GO Biological Process Annotations 2015	1.0	null
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
15845616-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OXRL-2626-SM-2I3F1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0592
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XXEK-1426-SM-4BRW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PMC5417597-pone.0176679.s006.xlsx-Tumor_MLL_vs_Control-Unnamed_1_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861312
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-2.17553
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323461
Exodeoxyribonuclease VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
PMC10967149-12903_2024_4167_MOESM3_ESM.xlsx-LPS_VS_LPS_PDLSC-CM_776-Gene_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AB-30-CR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.324065
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275313
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.22045
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2198
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.496078
abnormal appendicular skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.918
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23045
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
RNA polymerase II transcription regulatory region sequence-specific DNA binding	GO Molecular Function Annotations 2023	1.0	null
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20336
TCF21-23034159-E13_GONADS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thoracic spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
DA-40-HO94_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.585452
BE-73-KD75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394414
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52683
GTEX-WH7G-0526-SM-3NMBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53562
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6112
IZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68706
aromatic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
mesenchyme development	GO Biological Process Annotations 2015	1.0	null
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
collagen-containing extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.035
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353202
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53684
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25842
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36959
PMC11563688-jci-134-173448-s017.xlsx-EC2-gene_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07818
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UT-SCC-24A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08373
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.458006
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69766
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endochondral ossification	GO Biological Process Annotations 2023	1.0	null
prostate	HPA Tissue Gene Expression Profiles	1.0	0.914293
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235544
MB-15-ZF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22483
JURLMK1	CCLE Cell Line Gene CNV Profiles	1.0	1.39492
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_2126_KO_SUMO1_SRP299611	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264175
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22772
chronic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173314
MED21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80863
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89957
DNA-templated transcription	GO Biological Process Annotations 2023	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.429348
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41173
hacat	HPA Cell Line Gene Expression Profiles	1.0	1.08372
intracellular organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.437751
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11346
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
collagen type xiv trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.79652
Flexor digitorum profundus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.442
Geleophysic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
CB-02-XL81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.21296
Ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22906
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Cleft soft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
syndactyly	IMPC Knockout Mouse Phenotypes	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27059
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327027
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23416
GTEX-RUSQ-0326-SM-47JWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05292
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955464
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52824
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.731
Disorders of Sex Development	CTD Gene-Disease Associations	1.0	1.09436
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01707
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200328
vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7104-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
corn silk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.441426
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57257
DB-24-CQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.2553
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067354
chondrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.566828
sclerotome development	GO Biological Process Annotations 2015	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7961
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
thylakoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.139819
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.59424
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0367
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291612
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34812
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.08301
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.344183
Bone matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.875
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249649
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.627653
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16222
OPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77059
Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.125978
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.05126
MYC	ENCODE Transcription Factor Targets	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-190-ZNF707_ZNF707	Rummagene Transcription Factor Associations 2026	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533065
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WT1	ChEA Transcription Factor Targets	1.0	null
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882377
Osteocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.38
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29619
Perturb_12170_Mut_TP53_SRP287851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.75879
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293308
Thigh muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.633
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46362
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14438
resveratrol	CTD Gene-Chemical Interactions	1.0	null
BA-40-IU73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247254
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
positive regulation of embryonic development	GO Biological Process Annotations 2023	1.0	null
Bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.127
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25013
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.618
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861527
negative regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18001
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.682287
RE-62-FC93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438149
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995719
tetraspanin-enriched microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308867
KCNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55295
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.838027
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34938
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258064
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16989
positive regulation of developmental process	GO Biological Process Annotations 2025	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38589
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957751
Arthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Adenoma	CTD Gene-Disease Associations	1.0	1.14507
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.901641
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18502
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4123
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982957
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DB-18-UF01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.932126
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.478534
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Blastema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
tendon formation	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.774523
EC-37-MB09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.261304
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.78143
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
cellular_component	GO Cellular Component Annotations 2015	1.0	null
DA-23-TZ42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.425629
RPL36AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18353
restrictive cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.620617
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9315
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GLI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21152
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.233
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19907
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15585
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
mesoderm formation	GO Biological Process Annotations 2023	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.29688
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
intermediate stratum of p1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04261
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
SRPK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.374831
Long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
Bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.509
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.43207
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.289569
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.67995
PMC8787225-Data_Sheet_1.xlsx-STable_2_DEG-Supplementary_Table_2_1150_up-_and_down-regulated_differential_expressed_genes_upon_GATA2_activation_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93626
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.2149
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
plastid thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.275936
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49847
muscle phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE127790_6_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13364_KD_Wwtr1_SRP079400	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.10992
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95383
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11344
GTEX-T5JC-1926-SM-4DM6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874413
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55248
positive regulation of cellular process	GO Biological Process Annotations 2025	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4724
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8983_KD_MEOX2_SRP362177	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.872
YAMATO	DepMap CRISPR Gene Dependency	1.0	3.86284
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704688
Mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.001
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DA-27-BW40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311257
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
vacuole-isolation membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.787
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367495
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19582
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3448
collagen fibril organization	GO Biological Process Annotations 2015	1.0	null
Periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.961
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
embryonic	GeneRIF Biological Term Annotations	1.0	null
Perturb_8483_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.40277
Hypospadias	CTD Gene-Disease Associations	1.0	1.17464
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
interstitial nucleus of the posterior limb of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03616
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49341
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
Granulation tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393819
nucleus	GO Cellular Component Annotations 2023	1.0	null
Arteria profunda penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.773
KLF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.4145
GTEX-OIZI-1326-SM-3NB1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3037
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12697
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310409
heart valve formation	GO Biological Process Annotations 2015	1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363763
sc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49322
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vertebra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.307
RBMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31661
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26729
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01492
abnormal muscle morphology	MPO Gene-Phenotype Associations	1.0	null
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217152
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39125
Perturb_17409_KO_Kat7_SRP346204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.0376
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47025
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85328
JVM3	DepMap CRISPR Gene Dependency	1.0	2.03487
biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188916
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.69038
GF-35-IT27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.14686
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
regulation of multicellular organismal development	GO Biological Process Annotations 2025	1.0	null
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53285
synthesis	GeneRIF Biological Term Annotations	1.0	null
ROS-17/2.8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19233
Venous endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.29936
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.361
GTEX-PLZ4-0226-SM-2S1NW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
AB-43-XJ34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28786
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7840-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2455
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86025
positive regulation of collagen biosynthetic process	GO Biological Process Annotations 2025	1.0	null
Jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.82
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.554
Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10025
bl-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58242
regulatory region nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
Vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.467
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_14730_KD_MAZ_SRP338457	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.6059
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04637
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38196
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90078
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
scx	GeneRIF Biological Term Annotations	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04602
fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301039
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10165
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00285
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of embryonic development	GO Biological Process Annotations 2025	1.0	null
plastid stroma	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.250751
JE-72-KV75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252472
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34666
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936457
Perturb_13075_KO_Atm_SRP062722	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365757
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.97093
regulation of apoptotic process	GO Biological Process Annotations 2023	1.0	null
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26737
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358127
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62659
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914343
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18397
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19696
SLC39A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71676
Perturb_8484_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.10609
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.5627
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.46781
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21579
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.590437
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399242
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Myoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3526
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Perturb_5045_KO_Sall1_ERP014607	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.36498
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.788
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07484
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fibroblast_Connective tissue_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.789
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45851
RNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49609
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0118
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48252
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-POMQ-0426-SM-3P61G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825623
LCAM1	DepMap CRISPR Gene Dependency	1.0	5.34884
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.33369
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
KB-49-NF63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34155
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.4151
cellular response to transforming growth factor beta stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975385
chloroplast thylakoid membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.276671
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PD-60-FM93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329074
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Necrosis	CTD Gene-Disease Associations	1.0	1.65113
Perturb_9246_KO_Lin28b_SRP300815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890479
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16379
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36302
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31043
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28876
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39619
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Supplemental_Table_9_NEUROG3_bound_TFs_genes_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cartilage development	GO Biological Process Annotations 2023	1.0	null
NCIH1781	CCLE Cell Line Gene CNV Profiles	1.0	2.3769
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
abnormal sclerotome morphology	MPO Gene-Phenotype Associations	1.0	null
DB-78-NM13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283717
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
VD-76-SO91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.448957
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00305
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920725
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058531
GTEX-WWYW-0826-SM-3NB2X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57223
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23381
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8524
JD-87-KA71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285461
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.767
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-RTLS-0726-SM-46MV4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TE8	CCLE Cell Line Gene CNV Profiles	1.0	1.44211
associating	GeneRIF Biological Term Annotations	1.0	null
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.56
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
absent somites	MPO Gene-Phenotype Associations	1.0	null
AC-75-LR63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.594316
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.511496
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50401
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Primary somatosensory area, nose, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05411
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648127
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ulnar-mammary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
GSE190316,GSE190324_0_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16209
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7745
Tendon Progenitor_Tendon_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07234
flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.44181
sum-52 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58387
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997219
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29625
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36481
GTEX-WXYG-0926-SM-3NB2O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11746
skeletal system development	GO Biological Process Annotations 2015	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZA-63-AC60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297495
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.670878
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12094_KD_Cdkn2a_SRP169507	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
tendon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.55698
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08761
Holt-Oram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
FE-06-GR60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251571
regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
HC-38-KI38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253706
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.12771
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.093
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63183
Perturb_7115_OE_Mir378A_SRP047487	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.7626
regulation of transcription from rna polymerase ii promoter	GO Biological Process Annotations 2015	1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.8991
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
negative regulation of programmed cell death	GO Biological Process Annotations 2025	1.0	null
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49004
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	2.67332
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56873
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059229
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457481
BB-87-SF89_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.734057
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
negative regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
KIF20A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53773
MYOD1	ENCODE Transcription Factor Targets	1.0	null
prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254239
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.834572
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08431
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.608565
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_39_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
p2 portion of the parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43922
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
UF-06-JB00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208433
abnormal forelimb morphology	MPO Gene-Phenotype Associations	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25505
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10595
Epicondylitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.045
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Extensor digitorum communis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-14-GQ48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447356
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482601
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.975085
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15525
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEC116	DepMap CRISPR Gene Dependency	1.0	2.39253
TF-29-QU48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.402178
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M9-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79769
Coelom	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98925
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994684
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25603
GSE197948_2_v_0_atp7b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29173
scleraxis	GeneRIF Biological Term Annotations	1.0	null
AA-32-DP01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290401
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.93047
thus	GeneRIF Biological Term Annotations	1.0	null
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341982
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.68508
WPE1NA22	DepMap CRISPR Gene Dependency	1.0	2.89971
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-40-NS72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271845
TOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01784
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.637962
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.653807
regulation of multicellular organismal development	GO Biological Process Annotations 2023	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10039
JE-04-LS32_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258949
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06917
Calvarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE216043_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924169
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00101
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Eye-ciliary body	Tabula Sapiens Gene-Cell Associations	1.0	-0.0437916
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZD-78-BS65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201811
biological regulation	GO Biological Process Annotations 2015	1.0	null
Forelimb muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
positive regulation of multicellular organismal process	GO Biological Process Annotations 2025	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65569
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
XB-53-OZ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224305
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.931245
limbs/digits/tail phenotype	MPO Gene-Phenotype Associations	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.504318
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70329
positive regulation of gastrulation	GO Biological Process Annotations 2025	1.0	null
valve	GeneRIF Biological Term Annotations	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3655
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.981
motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.830291
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949792
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
IE-38-FB31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45054
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04331
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21408
JURKAT	DepMap CRISPR Gene Dependency	1.0	3.35163
GSE160077,GSE160084_3_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08674
Epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.238
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.167515
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89817
H3K36me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0226-SM-4B656	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38373
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.524
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
PMC12464728-HSR2-8-e71283-s003.docx-37-1450_ZNF260_1_ZNF260	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63805
HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3263
positive regulation of biosynthetic process	GO Biological Process Annotations 2023	1.0	null
PMC10925000-12885_2024_12075_MOESM2_ESM.pdf-5-HEY2_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7705468__F2	PFOCR Pathway Figure Associations 2023	1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.677259
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220432
Ankylosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12252
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-24-CQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35944
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12130184-12276_2025_1441_MOESM5_ESM.pdf-8-ZNF688_ZNF688	Rummagene Transcription Factor Associations 2026	1.0	null
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
DHRS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03642
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01398
extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.699543
PMC4564869__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982291
BCL3-23251550-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
appears	GeneRIF Biological Term Annotations	1.0	null
Red nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30306
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC11933697-41467_2025_58216_MOESM8_ESM.xlsx-SD6_ATF3_EV_NS1-SYMBOL_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	0.751371
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064014
BB-86-BE39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363508
AE-22-QI24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20691
GA-68-KC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204443
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of cartilage development	GO Biological Process Annotations 2023	1.0	null
QE-98-XD90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.682176
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10663
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.327581
Premature Birth	CTD Gene-Disease Associations	1.0	1.0637
EFE184	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68171
AB-71-CI37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213849
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21277
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
GSE77178_6_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ED-35-EX82_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.357155
SIRT4_KO_GDS4823_22_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13795
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844931
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35704
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01595
Myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
CB-83-LF14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205626
Geleophysic dysplasia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
BD-69-XG81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338237
GSE200352_1_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
blood serum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.411251
GSE185519_1_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.845618
Sarcoma_SARC_TCGA-JV-A75J-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sequence-specific dna binding	GO Molecular Function Annotations 2015	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.581822
reproductive process	GO Biological Process Annotations 2015	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02957
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848822
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.922585
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9228
TCF12_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.959057
Osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.904
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-04-NG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.686671
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
CAL29	DepMap CRISPR Gene Dependency	1.0	2.00862
Alexithymia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.728975
mRNA_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.617889
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
ERCC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33327
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.518
Complex of collagen trimers	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
extracellular matrix organization	GO Biological Process Annotations 2023	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.44226
AD-86-OB87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359392
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67573
Osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.867
GB-06-BA49_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.474555
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53795
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22153
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070793
Thoracic thymus_CT1_cortical thymic epithelial cell	HuBMAP ASCT+B Annotations	1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
developmental process involved in reproduction	GO Biological Process Annotations 2015	1.0	null
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04482
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373263
Perturb_9099_KD_SSX_SRP128693	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.3748
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458146
Progressive osseous heteroplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
prerubral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22884
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059535
immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046584
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12763
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500362
dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200663
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.975
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
modulate	GeneRIF Biological Term Annotations	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846247
KG-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63063
LD-69-ZV56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.27018
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05884
RNA biosynthetic process	GO Biological Process Annotations 2025	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01184
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19913
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4597
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893536
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1456
positive regulation of cartilage development	GO Biological Process Annotations 2025	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80747
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GE-29-ZM45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514164
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
several	GeneRIF Biological Term Annotations	1.0	null
TSC1-TSC2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
Hemorrhage	CTD Gene-Disease Associations	1.0	1.03456
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
digestive juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310783
PMC9240038-41467_2022_31337_MOESM5_ESM.xlsx-Sheet1-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q734-0826-SM-48U1G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856466
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.58065
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.377354
TC-95-IR96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318775
regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468436
bHLH transcription factor binding	GO Molecular Function Annotations 2023	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25776
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.444154
abnormal sclerotome morphology	MGI Mouse Phenotype Associations 2023	1.0	null
arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212413
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DB-29-HQ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243136
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	2.53216
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33575
KNS81	DepMap CRISPR Gene Dependency	1.0	2.56548
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74432
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165762
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173261
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.728241
CE-18-AP85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46385
single-organism process	GO Biological Process Annotations 2015	1.0	null
GSE214823,GSE214824_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thigh	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.415
GTEX-OIZG-0426-SM-3LK5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76495
squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07594
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326097
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.34782
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160574
GSE174383_1_v_0_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
upregulated	GeneRIF Biological Term Annotations	1.0	null
nucleoplasm part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
cartilage development	GO Biological Process Annotations 2023	1.0	null
Perturb_16406_KO_Vgll2_DRP005135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.45509
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.58959
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06259
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of collagen metabolic process	GO Biological Process Annotations 2025	1.0	null
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.434985
key	GeneRIF Biological Term Annotations	1.0	null
Perturb_7009_KO_Lmna_SRP217125	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.90531
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
WM115	DepMap CRISPR Gene Dependency	1.0	2.30395
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22531
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60125
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.05864
chondrogenesis	GeneRIF Biological Term Annotations	1.0	null
regulation of collagen biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GSE226114,GSE226116_2_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279011
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23082
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0202
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19827
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893122
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483432
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.309697
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.496483
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.960742
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11971
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31583
VD-88-MW70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.451839
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BB-77-QQ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.508793
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.67306
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adherens junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.102412
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.733683
GTEX-UJMC-0626-SM-4IHJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93331
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868801
GTEX-QV44-1825-SM-447CF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20482
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47V-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23734
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00096
abnormal embryonic tissue morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
Mural cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.982
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9161
WC-09-GD62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213853
positive regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.605399
SKMM2	CCLE Cell Line Gene CNV Profiles	1.0	1.63695
Perturb_11559_KO_CD274_SRP313849	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.066
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.888149
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584422
positive regulation of transcription by RNA polymerase II	GO Biological Process Annotations 2025	1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.69579
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.330053
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2151
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598067
JF-55-EN33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390693
KE-04-OV29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257015
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CE-03-YQ91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500188
PMC8948606-7488708.f2.docx-6-HSFX1_HSFX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93911
AF-83-BX08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09637
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FF-46-OR35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339934
preweaning lethality, complete penetrance	IMPC Knockout Mouse Phenotypes	1.0	null
conserved	GeneRIF Biological Term Annotations	1.0	null
cellular response to bmp stimulus	GO Biological Process Annotations 2015	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3128
Hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.944
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18194
abnormal limb bone morphology	MPO Gene-Phenotype Associations	1.0	null
A549	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.41784
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40013
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71117
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01731
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05113
Brain Lower Grade Glioma_LGG_TCGA-QH-A6XC-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD-97-ZV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296575
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.149
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91447
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991163
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
stigma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.556865
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MO-0326-SM-32QOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17843
GSE77178_1_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147613_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE123958,GSE123959_0_v_1_mta1_human	RummaGEO Gene Perturbation Signatures	1.0	null
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.752533
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55282
Acute Myeloid Leukemia_LAML_TCGA-AB-2927-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27776
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
response to mechanical stimulus	GO Biological Process Annotations 2015	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08509
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1147
Infertility, Male	CTD Gene-Disease Associations	1.0	1.17794
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.162306
face morphogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	2.7709
BE-59-WG31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271807
regulation of gene expression	GO Biological Process Annotations 2023	1.0	null
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91862
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43827
18081427-TableS8	GeneSigDB Published Gene Signatures	1.0	null
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01181