association	dataset	threshold value	standardized value
Inflammation	CTD Gene-Disease Associations	1.0	1.19835
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02325
GTEX-QCQG-1626-SM-48U26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
superficial stratum of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17933
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5868
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.5576
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37611
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXJ3_FOXJ3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833655
Sebaceous gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81565
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07716
nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43181
HUT78	CCLE Cell Line Gene Expression Profiles	1.0	1.38354
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4055
Perturb_9765_KO_Ikbkb/Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.75979
DCTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68075
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26658
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48679
GTEX-SUCS-0726-SM-4DM7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900333
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.172169
Epidermolytic hyperkeratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15228
TE9	CCLE Cell Line Gene Expression Profiles	1.0	1.82061
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60364
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17213
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.918
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17933
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
PLEKHG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87973
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.287
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875178
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15328
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842747
GSE157049,GSE157051_7_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
Hepatic Encephalopathy	CTD Gene-Disease Associations	1.0	1.26113
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.002
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6368
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.100978
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77897
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25222
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28092
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21878
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85553
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924515
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79193
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51481
cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.480855
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6223-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908154
SNU-354 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840923
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4914
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66837
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
glaucoma	GWASdb SNP-Phenotype Associations	1.0	0.358199
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1158
SDCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11762
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16416
NDUFA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03598
GSE171269_1_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02473
DPYSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58378
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29477
BXPC3	DepMap CRISPR Gene Dependency	1.0	2.64343
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1993
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16689
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Perturb_10920_KO_fatp2_SRP229353	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.90561
Eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192401
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062365
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67368
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055199
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64376
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JB-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5673
LN235	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00412
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HZ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16493
BAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66013
dorsal terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35755
PPIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29342
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76679
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
GSE160373_5_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.02077
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_11129_KO_Yap1_SRP281955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9578
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19864
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5929
NUGC3	CCLE Cell Line Gene Expression Profiles	1.0	1.52786
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02325
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.18548
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TKQ1-1126-SM-4GIAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.67639
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94628
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45X-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97754
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6865
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17438
TM2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61813
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
GSE124694_0_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Vitelliform macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
TP53I11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14801
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57859
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.105915
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51886
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29942
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49196
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96023
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03173
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895349
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30402
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25414
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01438
abnormal eye physiology	GWASdb SNP-Phenotype Associations	1.0	0.287297
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05236
GTEX-Q734-1026-SM-48U16	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.476951
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08137
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2309
GSE110303,GSE110304_1_v_2_estradiol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.44794
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62469
RLBP1	Pathway Commons Protein-Protein Interactions	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81749
NB17	DepMap CRISPR Gene Dependency	1.0	4.13409
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4733-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
APOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40181
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14398
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96696
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.067427
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50814
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19567
retinoid metabolic process	GO Biological Process Annotations 2025	1.0	null
Fundus albipunctatus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.491
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06863
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5493
TYK2_KD_GDS4754_158_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Smooth endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
CLPP_KO_GDS4791_375_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1562
Adrenocortical carcinoma_ACC_TCGA-OR-A5LG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.034094
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ8I-0826-SM-4BOOE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MLX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6779
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2684
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00129
HMOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RM2N-0826-SM-48FD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.12605
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29477
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16021
Dry Skin	DisGeNET Gene-Phenotype Associations	1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11331
Nuclear exosome targeting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.784
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80478
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1156
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38205
Disease	Reactome Pathways 2014	1.0	null
hsa-miR-3667-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ChIP_NACC1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2882-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67627
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.72488
GSE182834,GSE182836_2_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9379
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ichthyosiform Erythroderma, Congenital	DisGeNET Gene-Disease Associations	1.0	null
Hypotrichosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RNA helicase p68_KD_GDS2152_625_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053997
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41111
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.643009
SF767	CCLE Cell Line Gene Expression Profiles	1.0	1.74329
Perturb_8418_KO_Yap1/Wwtr1_SRP143461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.37595
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
TBK1_druginhibition_188_GSE53658	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.54442
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE216702,GSE216718_0_v_1_trex1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNA helicase p68_KD_GDS2152_626_mouse_skeletal muscle cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
columnar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.704764
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83159
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12383
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4485
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.245913
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36038
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917698
oxidoreductase activity	GO Molecular Function Annotations 2015	1.0	null
MONOMAC6	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.6139
JHH1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46817
HNF4A	ChEA Transcription Factor Targets	1.0	null
NELF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48598
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01471
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Epidermolysis bullosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864665
CHMP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85829
nonmotile primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.818993
TCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45263
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13375
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMAC-SF	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66409
ETFBKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87905
DON cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1541
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
intermediate stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45761
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993949
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.38389
hsa-miR-1257	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-PW2O-0826-SM-48TC5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13568
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50G-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oxidation-reduction process	GO Biological Process Annotations 2015	1.0	null
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11795
GTEX-UJMC-0926-SM-4IHLK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947255
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84921
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
Anhidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09242
Acute Myeloid Leukemia_LAML_TCGA-AB-2860-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE62843,GSE64370_0_v_1_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.888
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.168854
CAL120	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07815
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25185
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	1.63105
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.28415
L1236	CCLE Cell Line Gene CNV Profiles	1.0	3.23577
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
GTEX-XLM4-0726-SM-4AT64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919664
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16045
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SNU1214	CCLE Cell Line Gene Expression Profiles	1.0	2.65491
hsa-miR-320d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_10940_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.8477
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00846
basal part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17564
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06983
primary open angle glaucoma	GWASdb SNP-Phenotype Associations	1.0	1.1361
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200352_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-196a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral amyloid deposition (PET imaging)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
PMC2999557-pone.0015082.s016.xls-target_genes-top10_H3K9me3_SETDB1_overlap_SETDB1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11251_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.88026
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE246716_0_v_1_trappc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventromedial hypothalamic nucleus, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2218
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATP5MC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58589
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
GATA2	ChEA Transcription Factor Targets	1.0	null
ZNF347	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95936
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84808
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49473
NACC1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_11131_KO_Yap1_SRP281955	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	1.10601
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864342
CD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24435
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85962
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15117
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25613
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54153
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974252
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43885
Subiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64857
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16647
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.378
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85348
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22739
steroid metabolic process	GO Biological Process Annotations 2025	1.0	null
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64818
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047614
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10399
Perturb_11107_KO_Cpt2_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.646559
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40787
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10821
GSE157049,GSE157051_6_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GOLGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67032
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89239
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893624
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CE-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WY7C-0926-SM-3NB34	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25837
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47471
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055497
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22853
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083251
CTH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15237
GTEX-S32W-0426-SM-4AD6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834333
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58553
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22901
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
organelle part	GO Cellular Component Annotations 2015	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46594
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16913
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59693
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20712
MRPL44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53121
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941239
TP63	ChEA Transcription Factor Targets	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42139
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Subiculum, ventral part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12676
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QV31-0326-SM-447BM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEBP1_KO_GSE31150_52_mouse_pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36038
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49396
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGEF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19592
NCIH2122	Achilles Cell Line Gene Essentiality Profiles	1.0	1.92982
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04764
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71134
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44212
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6953-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10151
promotes	GeneRIF Biological Term Annotations	1.0	null
Hypergranulosis	DisGeNET Gene-Phenotype Associations	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
RNF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69054
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AM38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68466
hsa-miR-361-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TMBIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95519
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21889
Lung squamous cell carcinoma_LUSC_TCGA-77-8131-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78725
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6218-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.106
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.41776
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
CACFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78009
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4920-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Syndromic microphthalmia 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
FADS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09092
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.599
GTEX-XV7Q-0926-SM-4BRVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SREBF2	ChEA Transcription Factor Targets	1.0	null
Perturb_10866_KO_Hsf1_SRP116890	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.1287
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NCIH1792	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.32404
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57105
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.837234
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Congenital ichthyosis of skin	ClinVar Gene-Phenotype Associations 2025	1.0	null
JHOS-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54781
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937818
C1orf116	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82576
MPP89	DepMap CRISPR Gene Dependency	1.0	3.40451
EWS502	DepMap CRISPR Gene Dependency	1.0	2.83468
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40716
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7853
intermediate stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27204
Migraine	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.82219
abnormality of the small intestine	GWASdb SNP-Phenotype Associations	1.0	0.851701
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
FMR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2158
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
Hypertrophy	CTD Gene-Disease Associations	1.0	1.02671
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02921
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
Root caries	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.125
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.167
Rhabdomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.508
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4429	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90443
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MBD3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65319
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.56387
Vulvar leiomyosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2104
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841303
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86057
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_4_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Gangrene	DisGeNET Gene-Disease Associations	1.0	null
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941239
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06983
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.099
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84328
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.16069
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27813
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.09857
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.18859
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877517
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Pruritus	DisGeNET Gene-Phenotype Associations	1.0	null
Companion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908154
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824273
Interphotoreceptor matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.975
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_9_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19016
ZNF687	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84001
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65655
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68536
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18302
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85458
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PRKAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94127
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71064
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54169
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237711
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06983
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890797
Bothnia retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.03827
CDK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03041
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.906
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
TSPAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72143
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.5535
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34246
dry skin	MGI Mouse Phenotype Associations 2023	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78087
PBX1	ChEA Transcription Factor Targets	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eyelid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.043
BBC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44711
D502MG	DepMap CRISPR Gene Dependency	1.0	2.87383
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
Perturb_820_OE_Rspo1_SRP325709	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SKOV3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.85731
shell of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55651
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
probucol_mus musculus_gpl9523_gds3616	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3126-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04385
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Ectropion	DisGeNET Gene-Disease Associations	1.0	null
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65745
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Otosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
dorsal paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09088
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
UMUC7	DepMap CRISPR Gene Dependency	1.0	2.36121
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HR-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
Trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25346
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.86117
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95948
TMEM37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34728
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.28866
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.608
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05039
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62987
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.11926
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4776-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-1126-SM-3NMBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Leber congenital amaurosis 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Hyperkeratosis	DisGeNET Gene-Phenotype Associations	1.0	null
Urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73823
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831636
Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Branchial arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6220-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Abnormality Of The Helix	DisGeNET Gene-Phenotype Associations	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06356
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.245913
RLIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98686
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02158
CCDC78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62649
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4IQ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glucose/ribitol dehydrogenase	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07389
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73754
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	GO Molecular Function Annotations 2023	1.0	null
Perturb_10917_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Atopic dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
Syndromic microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.627
GSE162276_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plexiform layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18345
Perturb_10867_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.58077
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831636
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3RK-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMIM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61262
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
HDAC1	ENCODE Transcription Factor Targets	1.0	null
NANOG-21062744-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE165548_2_v_7_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98728
MCF-10F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44733
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57306
GTEX-OOBK-1026-SM-48TC2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87216
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8634-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93301
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.52635
COLO741	Achilles Cell Line Gene Essentiality Profiles	1.0	1.574
LOVO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.15646
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27272
Lung bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35924
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65416
Perturb_11206_KO_Mapk3/Mapk1_SRP331927	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SKMEL19	DepMap CRISPR Gene Dependency	1.0	5.08863
Perturb_10865_KO_Hsf1_SRP116890	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.74892
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4375
nucleolus	GO Cellular Component Annotations 2015	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC8326207__SF2	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8362
esophagus_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.862465
MTHFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89327
TMEM39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5118
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-PWOO-0626-SM-48TZH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885795
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03475
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05039
SRY	ChEA Transcription Factor Targets	1.0	null
Perturb_12557_KO_Aire_SRP033579	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.08054
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60469
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-2.41304
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07214
Dry Skin, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
duodenal ulcer	GWASdb SNP-Disease Associations	1.0	0.966812
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13332
GYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81237
EBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71149
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18374
Brain Lower Grade Glioma_LGG_TCGA-FG-A60J-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096388
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33857
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4977-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38376
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845277
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39071
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45917
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8235
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
ARPE-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
Congenital Nonbullous Ichthyosiform Erythroderma	DisGeNET Gene-Disease Associations	1.0	null
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065597
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23029
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057474
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17287
PCM6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69051
NB1	DepMap CRISPR Gene Dependency	1.0	3.84033
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
hsa-miR-645	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09025
KLF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56818
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33181
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06783
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53386
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16066
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56158
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.48256
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
SEM	Achilles Cell Line Gene Essentiality Profiles	1.0	1.36382
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980717
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12465
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_11310_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.927
Autosomal recessive congenital ichthyosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
CCLFUPGI0005T	DepMap CRISPR Gene Dependency	1.0	2.80828
all-trans-retinol dehydrogenase (NAD+) activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04092
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SO-01B-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61714
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9709
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MUTZ8	DepMap CRISPR Gene Dependency	1.0	5.00553
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53084
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849458
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Allergic contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53502
KLF4	ChEA Transcription Factor Targets	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.1977
r6 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34332
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.334
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52775
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04075
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.042
CW2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6327
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
SNU1077	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69802
GSE163920_1_v_0_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50303
LIFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15994
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42805
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04137
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6152
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841108
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34034
peptic ulcer disease	GWASdb SNP-Disease Associations	1.0	0.966812
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.264819
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-S3XE-1826-SM-3K2B4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57536
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248858_5_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44855
CMK86	CCLE Cell Line Gene Expression Profiles	-1.0	-2.62283
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87102
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847819
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1975	DepMap CRISPR Gene Dependency	1.0	2.97603
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917698
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
NCIH23	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.37462
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
STAT1_KD_GDS4754_159_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.24
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.55
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07866
Necrosis	CTD Gene-Disease Associations	1.0	1.70265
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.855
duodenal ulcer	GWASdb SNP-Phenotype Associations	1.0	0.851701
GSE200352_9_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44535
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06983
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70038
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13933
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-0526-SM-32QOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131903_0_v_2_abca12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.68549
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.91686
GMS10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37887
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.892828
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05453
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08984
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40595
PEBP1_KO_GDS4334_617_mouse_Pancreatic beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15236
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70855
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20412
CFPAC1	DepMap CRISPR Gene Dependency	1.0	2.56253
GTEX-WFON-1826-SM-3GILG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
hsa-miR-196b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-7636-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3-24758297-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE171269_1_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU216	DepMap CRISPR Gene Dependency	1.0	2.03643
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93889
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05708
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36798
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186393
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02985
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NCIH1703	DepMap CRISPR Gene Dependency	1.0	2.54387
hsa-miR-34c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27196
The canonical retinoid cycle in rods (twilight vision)	Reactome Pathways 2014	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE160373_8_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09397
GTEX-OHPK-1526-SM-3MJGM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25072
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31071
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32145
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054774
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8064
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4148
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.806
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12317
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84902
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848468
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.034177
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sublayer 6a of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03692
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33395
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46813
GSE160373_1_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39048
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MK-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92459
alcohol dehydrogenase (NAD+) activity	GO Molecular Function Annotations 2025	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908218
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57168
Autosomal recessive congenital ichthyosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.785
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6477-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894802
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941239
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.65
Nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TFAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31487
GSE185944_0_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R53T-0426-SM-48FEM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
nuclear part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
POLR2A	ENCODE Transcription Factor Targets	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82088
G-401	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18736
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854939
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10862
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WH7G-2326-SM-3NMBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03811
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2684
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32705
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46966
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899881
GTEX-XUZC-0726-SM-4BOPH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.48205
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23432
BL1297 (IRS1)	NURSA Protein Complexes	1.0	null
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36412
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06132
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32868
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.0394
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Eyespot apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
Congenital Ichthyosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849956
LS411N	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.17043
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834333
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055524
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pericardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.641238
NPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30604
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60291
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20045
organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16852
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
WM983B	DepMap CRISPR Gene Dependency	1.0	3.08841
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-371b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25864
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3579
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46689
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64742
Sparse Hair	DisGeNET Gene-Phenotype Associations	1.0	null
RH30	DepMap CRISPR Gene Dependency	1.0	5.39916
U7 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.157
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.688
WM115	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35288
Perturb_11086_KO_Atf6_SRP332137	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.92078
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39685
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974814
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.312
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26396
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.06987
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GS-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65349
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4725-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
HDAC6	ENCODE Transcription Factor Targets	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75145
leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.997814
hip	GAD Gene-Disease Associations	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0092
GTEX-SUCS-1826-SM-32PM1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
abnormality of the duodenum	GWASdb SNP-Phenotype Associations	1.0	0.851701
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.69
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
hsa-miR-758	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9612
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-S32W-0726-SM-2XCBL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.417644
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49396
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31814
Lack Of Skin Elasticity	DisGeNET Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15999
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
partly	GeneRIF Biological Term Annotations	1.0	null
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939948
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01136
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52922
GTEX-WFON-0626-SM-4LVLX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-V955-1126-SM-4JBH3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865778
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40268
SERINC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59355
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902478
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.02732
GSE139455_2_v_1_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39642
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.23252
superficial stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09088
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
SNU387	DepMap CRISPR Gene Dependency	1.0	2.19533
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17617
Prostate adenocarcinoma_PRAD_TCGA-G9-6378-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614571
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2816
Solar retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
DNAJB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4087
hsa-miR-3121-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
metastasis	GeneRIF Biological Term Annotations	1.0	null
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38932
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058932
Mature chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.086
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25094
MYC	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48151
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7841
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74174
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05932
JUP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68334
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23042
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
2.2.15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099957
Ichthyosis vulgaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.008
LS513	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11234
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.4192
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08429
GSE205021_3_v_1_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.085
Asthma or allergic disease (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.20969
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050759
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.071681
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.64871
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.315
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20167
RENBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74642
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFO21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.6644
Fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1839
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2487
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-2.46212
Onychomycosis	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A47Z-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONDA9	DepMap CRISPR Gene Dependency	1.0	2.91683
Alzheimer's disease (survival time)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
ASCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66053
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17287
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66574
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7485
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40787
HCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92884
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895479
Lymphangioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10692
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37332
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14847
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918414
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL5	Achilles Cell Line Gene Essentiality Profiles	1.0	1.16255
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13256
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.138012
RBFOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79902
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01162
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.6535
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840422
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07982
Recurrent Respiratory Infections	DisGeNET Gene-Phenotype Associations	1.0	null
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52148
cell part	GO Cellular Component Annotations 2015	1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
RUNX1_KO_GDS1511_251_mouse_Embryos at E12	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94622
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09955
arthrogryposis, renal dysfunction, and cholestasis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
NCIH526	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03163
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.986
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.194
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	1.0	1.76559
nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18722
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
tonsil_8e1	HPA Tissue Sample Gene Expression Profiles	1.0	0.867188
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.8815
Principal sensory nucleus of the trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37718
SNU1041	DepMap CRISPR Gene Dependency	1.0	3.47472
esophagus	HPA Tissue Gene Expression Profiles	1.0	1.14069
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45931
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12744
RACK7-27058665-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OSBPL1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76485
FOXA2	ChEA Transcription Factor Targets	1.0	null
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46398
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2695
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998188
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.111
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16637
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49396
ABL1_druginhibition_77_GSE24493	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.54425
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06126
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09837
GTEX-QDVJ-1726-SM-2I5FX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42298
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.91301
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01233
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
GLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35659
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139455_0_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.158
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RUNX1	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57285
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20994
vagina	HPA Tissue Protein Expression Profiles	1.0	1.36752
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6961-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55118
morphological abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.145994
Short-chain dehydrogenase/reductase, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.5381
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861589
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.669
hsa-miR-4491	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MM370	DepMap CRISPR Gene Dependency	1.0	3.44728
GTEX-U3ZM-1526-SM-3DB9D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07978
Perturb_11270_KO_Bmal1_SRP337469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.80238
GSE237040_2_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.53848
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	1.36752
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Macula lutea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6672
craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121288
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.880871
esophagus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LHX9_LHX9	Rummagene Transcription Factor Associations 2026	1.0	null
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04828
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939948
epidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68869
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939948
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XXEK-0726-SM-4BRWF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JC-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.257711
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86531
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865392
hsa-miR-320c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.03678
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45018
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11325
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-XBED-2326-SM-47JYR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11495
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DNMT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5498
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30979
GSE160373_1_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939948
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.226
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.36752
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9824
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3996
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.11359
FOXA1	ENCODE Transcription Factor Targets	1.0	null
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1996
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.06008
CLCN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71111
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68225
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32132
Hypohidrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.891
NUDCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88885
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24106
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4726-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL24	DepMap CRISPR Gene Dependency	1.0	2.23153
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61897
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60904
hsa-miR-4506	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850044
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.406
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055369
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07318
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BI-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14516_KO_Kras_SRP311976	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.71729
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.43922
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03891
PTEN_01_302	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.46173
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20288
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48334
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.183
EFR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53318
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03016
BL70	CCLE Cell Line Gene Expression Profiles	1.0	2.15179
GSE211286_7_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-CoV MA15_Day7-PFU-10^4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.86252
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10973
TMEM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28275
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02709
dorsolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08957
cl-48 cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1564
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37987
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54437
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061427
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12383
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056623
abnormality of the intestine	GWASdb SNP-Phenotype Associations	1.0	0.22261
Cone dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.921
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73756
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.214975
layer 6 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05754
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bullous congenital ichthyosiform erythroderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312957
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13466
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6829
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67485
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25992
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873196
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32513
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857064
Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33206
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45018
GSE162276_4_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QV44-0926-SM-2S1RH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.51636
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05159
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.009
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5398
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3QE-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11094_KO_Regnase1_DRP004811	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-PIO_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30847
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
CLPP_KO_GDS4791_539_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RPMI7951	DepMap CRISPR Gene Dependency	1.0	3.8544
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49488
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Abnormality Of The Dentition	DisGeNET Gene-Phenotype Associations	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Otosclerosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95717
PMC12263605-DataSheet1.pdf-415-LIN54_LIN54	Rummagene Transcription Factor Associations 2026	1.0	null
oxidoreductase activity, acting on ch-oh group of donors	GO Molecular Function Annotations 2015	1.0	null
Perturb_11297_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05453
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3285
BT-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05105
hsa-miR-1237	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0724
GSE157594_6_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
retinol dehydrogenase activity	GO Molecular Function Annotations 2015	1.0	null
GSE70499_3_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A204	Achilles Cell Line Gene Essentiality Profiles	1.0	1.92445
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60212
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15702
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01392
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.8069
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7407
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
RecFOR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18441
liver cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-R53T-0826-SM-48FCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE248858_1_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE207914_1_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57051
retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.726918
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28636
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5498
Perturb_10734_KO_Mettl14_SRP282531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9733
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10973
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.95
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054572
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09818
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_9766_KO_Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.05816
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08103
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01541
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE224877_2_v_1_pctp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11083
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31791
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14415
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54995
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22425
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.691
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65597
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.965
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70563
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
HMC18	CCLE Cell Line Gene Expression Profiles	1.0	1.80566
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.276
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87748
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.65824
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02572
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.728
APOBEC3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12656
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12739
U6atac snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.193
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
MMP23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66683
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39079
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66837
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838283
FREY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22373
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834333
SKOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22509
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02673
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63268
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.042
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_11332_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12717
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.26175
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
nuclear part	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962554
postnatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894776
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
NCIH1975	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0606
X-linked chondrodysplasia punctata 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14319
Lung squamous cell carcinoma_LUSC_TCGA-94-8490-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Recurrent corneal erosion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
TCTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85352
ETFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31577
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cos-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459918
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
FOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47277
GSE211931_1_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32188
Perturb_16830_KO_Cldn18_SRP096968	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14569
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068192
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27096
PTPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31364
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14309
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941239
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908154
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.986359
Stargardt disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.078
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9314
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5696
cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132434
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A652-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyramidal layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13375
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8125
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86952
Brain Diseases	CTD Gene-Disease Associations	1.0	1.08513
GTEX-UPJH-0326-SM-3GADU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06955
GTEX-XUW1-0326-SM-4BOOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83455
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.26732
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-T_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156688
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60118
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18891
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18114
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832968
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75645
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8063
KLF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41124
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10036
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55374
medial amygdala, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03981
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_10891_OE_Trim24_SRP355273	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.52593
GB1	CCLE Cell Line Gene CNV Profiles	1.0	2.55054
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Leber congenital amaurosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66507
Squamous Cell Carcinoma Of Esophagus	DisGeNET Gene-Disease Associations	1.0	null
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8316
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04649
Depressive symptoms (binary sum-score)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
GSE130246_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33562
GSE221101_1_v_0_hopx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8578301__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Autosomal recessive congenital ichthyosis 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.92091
Pityriasis rubra pilaris	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A901-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Liver Diseases	CTD Gene-Disease Associations	1.0	1.35962
Brain Lower Grade Glioma_LGG_TCGA-HW-8321-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NACC1	ChEA Transcription Factor Targets	1.0	null
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
ZEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4742
Visual phototransduction	Reactome Pathways 2024	1.0	null
GTEX-PWOO-2026-SM-48TDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953066
GLI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42927
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865025
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051042
photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.899499
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69191
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46359
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ainhum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952936
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17564
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.646953
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75277
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.134
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25613
T24	DepMap CRISPR Gene Dependency	1.0	2.61787
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
Perturb_10941_KO_Fto_SRP094101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.95665
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0569
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93431
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32618
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61615
mmp11	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.65376
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27011
Autosomal recessive congenital ichthyosis 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Migraine without aura	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.53979
SNU216	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46734
GTEX-QDVN-2026-SM-3GAEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3432
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BL1804 (MTA1)	NURSA Protein Complexes	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1077
Acute Myeloid Leukemia_LAML_TCGA-AB-2891-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	13.8088
C3orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11113
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16258
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02325
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42795
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.45862
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
JM1	CCLE Cell Line Gene CNV Profiles	1.0	2.17534
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19379
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3322
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98075
CDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63929
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67891
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7677
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00796
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CESS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82826
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14359
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Isolated microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.2068
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
hsa-miR-3679-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7268
GTEX-XPVG-2726-SM-4B66W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.58343
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10833
skin	HPA Tissue Gene Expression Profiles	1.0	1.77333
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Photosensitive trichothiodystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.786
REC1	CCLE Cell Line Gene CNV Profiles	1.0	2.10751
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00787
OCI-M1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50023
DICER1_Deficiency_GDS3685_518_mouse_Hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.8534
Somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.462
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52496
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78013
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41639
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QKI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83771
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-WFG7-1526-SM-4LVMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28143
LP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876863
A-Netherlands-602-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74369
GTEX-S32W-2026-SM-4AD6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15188
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39192
Perturb_11288_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC6591464-Table_4.xlsx-Sheet_1-Non-AIRE_regulated_genes_random_set_2_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ZMYM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51593
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54902
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.8867
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12118
GAS2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91852
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09632
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nematocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ID1_01_118	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.22865
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5557-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.58969
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947931
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95948
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
NCOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5472
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86378
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3332
Nuclear cap binding complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64769
single-organism process	GO Biological Process Annotations 2015	1.0	null
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18392
ZNF217	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8438-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CJ-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.509
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04412
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09168
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5373-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alopecia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76884
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946121
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053793
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57736
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04532
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77515
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2227
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N6-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cicatricial lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P7-A5NX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45498
KMS11	DepMap CRISPR Gene Dependency	1.0	4.26204
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45398
Cnidoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60742
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7939
496100441_PCx_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3813
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_15133_OE_Klf10_SRP360603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.4329
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117314
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
A4/FUK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.6372
GTEX-OIZI-0726-SM-2XCEI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
496100357_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02322
ONS76	DepMap CRISPR Gene Dependency	1.0	3.67028
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.91
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21089
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cornified envelope formation	KEGG Pathways 2026	1.0	null
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
Organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
Perturb_17487_KO_Elavl1_SRP153419	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.30603
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
GTEX-U4B1-1126-SM-4DXV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11331
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.935442
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26163
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62009
Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lagophthalmos	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.357
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5014
ZCCHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15294
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892758
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941239
Sweat gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.506
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLPP_KO_GSE40207_394_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68554
GSE116930,GSE116935_1_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08279
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95948
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4123
KALS1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.60303
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13464
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052395
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.34051
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75062
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.42993
FAM110D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96818
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.48013
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067068
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939403
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
PPARA_agonist activation_GSE17250_475_mouse_Isolated hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03173
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
retinol metabolic process	GO Biological Process Annotations 2025	1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chronic Otitis Media	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4696-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.84603
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.096353
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22451
NCIH1573	CCLE Cell Line Gene Expression Profiles	1.0	1.49592
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A_CA_04_2009_4dayMOI-10^5_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32863
Chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.716
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_10860_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.2662
GTEX-R53T-1326-SM-48FCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55599
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XQ8I-2126-SM-4BOOM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.599
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.13724
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07318
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
PMC3644282-1471-2164-14-110-S3.xls-Contextual_Gene_Set_Ref_Can-DLX3_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0923
Keratitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
CJM	DepMap CRISPR Gene Dependency	1.0	3.11674
UACC257	DepMap CRISPR Gene Dependency	1.0	4.31697
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.559601
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cicatricial ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70678
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831636
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.29994
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05453
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
ENHO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81647
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52395
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.622967
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.989
adrenal gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.947727
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
L428	DepMap CRISPR Gene Dependency	1.0	3.04227
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC6275272-FEB4-8-1977-s006.docx-1-Supplementary_Table_S2_Upregulated_genes_under_MYC_knockdown_in_AMU-ML2_cells_1_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15153
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7367-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.788733
molecular layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01712
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043171
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17167
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64347
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32668
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25453
SRP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21263
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78605
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47611
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_11073_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.13852
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7526
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906886
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P78B-0826-SM-3NMCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QCQG-0426-SM-48U29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Subiculum, dorsal part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24265
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939948
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871055
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831636
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53022
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94831
HCC15	DepMap CRISPR Gene Dependency	1.0	3.44923
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35691
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62788
PAPOLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07098
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
CAMKV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47163
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20626
FHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83137
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831636
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.08074
Smooth endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.368
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
Keratohyalin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.158
Kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE228894_3_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18807
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042612
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_16439_KD_IL13RA1_SRP314695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8697
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6998-01A-23R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.078
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24777
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8219
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56106
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851698
C2orf69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97829
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
lipid metabolic process	GO Biological Process Annotations 2025	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36822
primary cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.639717
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
enrichment culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1266
MRPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46812
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3866
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QDVN-1226-SM-48TZ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95132
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13028
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Eversion Of Lower Lip	DisGeNET Gene-Phenotype Associations	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0402
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8961
THAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7665
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0754
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	1.47113
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26777
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70215
ZNF385C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873595
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3IB-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11321_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
496100513_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94155
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epidermal hyperplasia	MGI Mouse Phenotype Associations 2023	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45761
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
OCI-LY7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRO-1226-SM-48TDL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUU-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83479
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.412
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NCIH596	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40302
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36368
embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PGRMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65435
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44879
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4087
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PIK3CA_mutant_27_GDS4053	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.93128
Liver hepatocellular carcinoma_LIHC_TCGA-ZP-A9D2-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2151
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.978
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE226452_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CLPP_KO_GDS4791_106_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
esophagus_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.904164
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A217-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Netherton syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.643
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CUX1	ChEA Transcription Factor Targets	1.0	null
Autosomal recessive congenital ichthyosis 4B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.775
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1704
HES3_KO_GSE64449_186_mouse_Min6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
Enlarged vestibular aqueduct	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
PPP1R17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30605
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39014
COLO684	CCLE Cell Line Gene Expression Profiles	-1.0	-2.47318
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996403
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_10943_KO_Crtc1_SRP279598	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.94832
squamous	GeneRIF Biological Term Annotations	1.0	null
Headache	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.6301
hsa-miR-650	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Palmoplantar keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.021
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS34	CCLE Cell Line Gene CNV Profiles	1.0	1.51158
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10197
AKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34636
Photosensitive trichothiodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
oxidoreductase activity, acting on the ch-oh group of donors, nad or nadp as acceptor	GO Molecular Function Annotations 2015	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82855
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70744
JVM3	DepMap CRISPR Gene Dependency	1.0	2.86025
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990137
Benign vascular tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3352-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824919
fetal cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867775
GSE94768_3_v_2_pofut1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_1_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
KCTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69071
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.890103
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22464
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44504
BICR18	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67601
NREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79479
GTEX-WH7G-1526-SM-4LVMX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7164
TBC1D13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41185
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
Neoplasms	CTD Gene-Disease Associations	1.0	1.12805
Excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.265
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
MRPL54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69496
Diaphragm disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13884
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874755
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6301
Regular astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
GRIPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53713
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01712
hsa-miR-3646	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
layer 5 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43387
Perturb_11576_KO_Zip8_SRP344283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.82666
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41003
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37878
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4657	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856889
FTC133	DepMap CRISPR Gene Dependency	1.0	2.65067
Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11071_KO_Slc10a1_SRP174097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.699
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ACAA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21129
MM383	DepMap CRISPR Gene Dependency	1.0	3.83299
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17978
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5111
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.148593
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30403
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
OCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68416
tonsil	HPA Tissue Gene Expression Profiles	1.0	1.05767
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Dorsomedial nucleus of the hypothalamus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06942
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
STEAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3331
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-320a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.25913
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6464
placenta	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.241
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9227
hsa-miR-4283	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MATN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7002
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Ectropion	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.464
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25694
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.187
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36767
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10959
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.865392
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990867
SLC16A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04865
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
SKNEP1	DepMap CRISPR Gene Dependency	1.0	2.484
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
INA6	DepMap CRISPR Gene Dependency	1.0	4.85272
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Secondary Malignant Neoplasm Of Lymph Node	DisGeNET Gene-Disease Associations	1.0	null
COS-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
SNU213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41347
LETMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93015
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12383
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
PANC0327	CCLE Cell Line Gene CNV Profiles	1.0	1.589
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1727
FEM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62015
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-3612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
Tail bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15323
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.36752
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39859
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2684
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50093
SET2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29477
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.66802
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KMS11	CCLE Cell Line Gene CNV Profiles	1.0	2.00988
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.824
CNOT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.585
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27485
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9146
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41912
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01975
TT	CCLE Cell Line Gene Expression Profiles	1.0	2.10639
YD38	DepMap CRISPR Gene Dependency	1.0	7.01054
GTEX-WFJO-1926-SM-3GILA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
steroid metabolic process	GO Biological Process Annotations 2023	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02325
GSE68229_0_v_1_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91118
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6274
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RAB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38822
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75591
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926793
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
SW1417	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNAI2_01_225	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.96191
GTEX-TMMY-1926-SM-4DXUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893616
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
abnormality of the gastrointestinal tract	GWASdb SNP-Phenotype Associations	1.0	0.106799
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05043
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Colon adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7411-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51647
ZBTB40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42044
TDRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69043
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69936
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.1086
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
CBY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14688
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.57375
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14539_KO_Kras_SRP311976	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.87595
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85829
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26303
RL952	CCLE Cell Line Gene Expression Profiles	1.0	1.85213
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hip	dbGAP Gene-Trait Associations	1.0	0.636184
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57162
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5010-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34717
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5887
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.846844
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE130246_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal recessive congenital ichthyosis 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.398
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14167
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3134
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17665
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.37616
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
Perturb_10872_KO_fatp2_SRP229353	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.17396
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.051419
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15616
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833787
OCILY19	DepMap CRISPR Gene Dependency	1.0	2.98569
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18785
RERFLCKJ	CCLE Cell Line Gene Expression Profiles	1.0	2.00404
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.866265
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82088
GTEX-U3ZN-2626-SM-3DB7T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32271
MEX3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80532
PAQR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32347
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
RMUGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30306
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4852-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nail Abnormality	DisGeNET Gene-Phenotype Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23009
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952195
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79365
ZNF529	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3817
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26786
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00411
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26462
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RDH11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67712
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0476
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13262
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5825
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61027
Rkip1_KO_GDS4331_15_mouse_C57BL/C pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77867
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
ELOVL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54013
VMRC-LCD	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.34628
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45V-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HCC44	DepMap CRISPR Gene Dependency	1.0	2.03543
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22791
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1639
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PGC-1alpha_Deficiency_GDS4904_311_mouse_Aged gastrocnemius muscle - 24 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91765
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
TP53I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10307
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72595
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.03159
GPSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47739
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
Cholestasis	CTD Gene-Disease Associations	1.0	1.01437
carotid stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.672722
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
organism form	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
Diseases associated with visual transduction	Reactome Pathways 2014	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61858
Lung squamous cell carcinoma_LUSC_TCGA-34-5236-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypervitaminosis A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
MKN-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48521
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25U-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ES8	DepMap CRISPR Gene Dependency	1.0	2.94516
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24747
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.725
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07866
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
Short-chain dehydrogenase/reductase SDR	InterPro Predicted Protein Domain Annotations	1.0	null
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.62491
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
FAM136A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19352
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18253
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14847
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05453
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ATP1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96586
NAD	CTD Gene-Chemical Interactions	1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.842
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73839
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29477
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7071-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TKKK	DepMap CRISPR Gene Dependency	1.0	3.21906
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08848
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055613
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997543
STAT3	ChEA Transcription Factor Targets	1.0	null
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02107
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.7
AKAP17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64976
MACF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
Hyperkeratosis	DisGeNET Gene-Disease Associations	1.0	null
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54241
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.51962
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12408
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0066
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79811
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16863
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3516
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836826
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831636
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.903
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.6184
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.31991
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26512
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
primary alcohol metabolic process	GO Biological Process Annotations 2025	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7831
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.044688
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868652
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U343	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3887
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939948
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RO82-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PEMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72622
PIGV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51906
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26008
A4FUK	CCLE Cell Line Gene CNV Profiles	1.0	1.94005
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895763
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64712
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26156
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Sjogren-Larsson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.908
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6667
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
NR0B1	ChEA Transcription Factor Targets	1.0	null
TBRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5025
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908154
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055975
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
disease	GWASdb SNP-Disease Associations	1.0	0.033899
VMCUB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80152
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92467
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.36541
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930386
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838779
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.061092
Palmoplantar Keratosis	DisGeNET Gene-Disease Associations	1.0	null
EFE184	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.2808
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.87385
Autosomal recessive congenital ichthyosis 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
Septohippocampal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2594
Familial lung cancer	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
YIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8695
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93889
GSE157049,GSE157051_6_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CLPP_KO_GSE40207_379_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17933
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18502
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89127
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939261
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44295
ENAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51182
Intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
STX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34673
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11105_KO_Tsc1/Depdc5_SRP219943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64869
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187474
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCC9	CCLE Cell Line Gene Expression Profiles	1.0	3.40793
CREB3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86677
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60041
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hair disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939948
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36246
prostate	HPA Tissue Protein Expression Profiles	1.0	1.36752
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052246
Autosomal recessive congenital ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.135
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2703
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28089
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Integrin alpha4-beta7 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834333
KLF4-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Hepatitis	CTD Gene-Disease Associations	1.0	1.10353
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29734
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44469
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.869878
FOS	ENCODE Transcription Factor Targets	1.0	null
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
heart muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
Perturb_18149_KO_Ikbkb/Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.36672
MV411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.53077
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0871
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281423
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6488
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
F-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
Massive Hepatic Necrosis	CTD Gene-Disease Associations	1.0	1.0189
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09088
ZNF75D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74617
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831636
Congenital diaphragmatic hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.98591
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826723
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Adrenocortical carcinoma_ACC_TCGA-PK-A5HB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.102
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.73924
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32006
NCIH660	CCLE Cell Line Gene CNV Profiles	1.0	1.68176
C11orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12955
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.131376
PMC9240646__F7	PFOCR Pathway Figure Associations 2024	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.957607
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33476
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SMPDL3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8931
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
hsa-miR-4670-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.079193
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54388
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.599
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31515
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49519
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.998596
Ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6138
CTV1DM	DepMap CRISPR Gene Dependency	1.0	2.11176
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53303
superficial stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34071
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57037
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0226
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982137
Perturb_18150_KO_Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.1852
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13086
BAZ1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55682
BTBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08804
HLA-C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97213
KSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36967
TMEM121B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98126
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3N5-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975685
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8438
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SF126	Achilles Cell Line Gene Essentiality Profiles	1.0	1.54247
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02011
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
SF126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.34572
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acne	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02059
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2684
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62108
Perturb_5695_KO_Tug1_SRP176442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.02989
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.52559
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69492
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.357
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NCOA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59186
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.342233
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09795
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40934
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.560616
RAGE_knockout_267_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.21498
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859974
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40686
RES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.416
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4116
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5783
3T3-F442A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-1226-SM-46MW7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835592
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85906
probucol_mus musculus_gpl9526_gds3619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73831
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03953
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
fundus albipunctatus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.86873
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X638-0126-SM-47JZ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02618
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.76489
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE70499_4_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPP2R2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20969
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17341
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57371
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03904
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04908
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34246
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27563
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15632
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
dorsal part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39457
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11475
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Subiculum, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52174
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43156
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58907
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5970-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33497
Brain Lower Grade Glioma_LGG_TCGA-DU-7008-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834333
GSE160373_5_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829181
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40646
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5864
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.91823
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42212
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25343
Prostate adenocarcinoma_PRAD_TCGA-EJ-5509-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
carotid artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.594454
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49658
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F8_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53142
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04265
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.371107
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1	ENCODE Transcription Factor Targets	1.0	null
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.981282
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63797
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08017
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68577
Leber congenital amaurosis 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16134
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Perturb_10916_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17416
Perturb_10230_KD_FOXC1_SRP068208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.96921
ACSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99309
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.75487
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73216
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
POLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31819
GTEX-OXRL-0126-SM-2YUMP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846489
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
hsa-miR-615-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45021
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87265
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99671
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34085
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08673
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
L428	CCLE Cell Line Gene CNV Profiles	1.0	1.80453
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.541377
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	1.14816
GSE160373_8_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66486
retinal disease	GWASdb SNP-Disease Associations	1.0	0.289954
MYC	ChEA Transcription Factor Targets	1.0	null
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01027
hsa-miR-449a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0617
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83834
LMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26779
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NAD-retinol dehydrogenase activity	GO Molecular Function Annotations 2023	1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5667
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
CENPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73286
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8723
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07348
mantle zone of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39457
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PPM1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10205
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9322
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Mesonephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50303
Perturb_11106_KO_Wtap_SRP310501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-XXEK-0126-SM-4BRVU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UOK101	DepMap CRISPR Gene Dependency	1.0	3.0685
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0417
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207914_0_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3346-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AQP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50822
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99486
MXRA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70035
Prostate adenocarcinoma_PRAD_TCGA-FC-7961-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26761
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
GSE94768_5_v_2_pofut1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal epidermis stratum corneum morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_11198_KD_Pten/Scap_SRP311091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE248858_6_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02289
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-4633-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92764
Colonic benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
CASKI	DepMap CRISPR Gene Dependency	1.0	2.34479
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5937
Neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
SERF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51337
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937899
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.39238
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5264
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.091
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Autosomal dominant mutilating palmoplantar keratoderma with periorificial keratotic plaques	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9795
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01394
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879946
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
FGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35666
jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.397979
abnormal corneocyte envelope morphology	MGI Mouse Phenotype Associations 2023	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92898
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44223
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16446
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80875
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.988885
hsa-miR-320b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91356
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053742
CGTHW1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68718
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992115
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Lamellar ichthyosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
BIRC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69657
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96578
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ZNF875	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08366
JEKO1	CCLE Cell Line Gene CNV Profiles	1.0	1.7423
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33212
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75299
GTEX-XUJ4-1626-SM-4BONV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03483
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86396
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65965
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3599
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73969
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
OVK18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7901
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3978
NEUROD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87815
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.294
MYPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69663
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38991
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41362
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039927
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Signal Transduction	Reactome Pathways 2014	1.0	null
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54712
weight loss	MGI Mouse Phenotype Associations 2023	1.0	null
NCOA2_KO_GDS4785_172_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49396
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76679
GTEX-VUSG-2526-SM-4KL1V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39285
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20316
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.974252
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive congenital ichthyosis 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5495
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.38111
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10720_KO_Setd2_SRP220107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.10822
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
ANGMCSS	DepMap CRISPR Gene Dependency	1.0	2.92887
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1634
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5042
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32201
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RESF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38224
Lung squamous cell carcinoma_LUSC_TCGA-66-2788-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03475
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860844
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.26408
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Interphotoreceptor matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.72
Sarcoma_SARC_TCGA-QQ-A5VA-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-34a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ1-0226-SM-33HB5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QDVJ-1226-SM-48U1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SLC27A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2516
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23462
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ5-2026-SM-2S1O4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36918
esophageal	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4229
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36759
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56834
MAFK	ENCODE Transcription Factor Targets	1.0	null
BLTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17486
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925908
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AU565	CCLE Cell Line Gene Expression Profiles	1.0	1.66009
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82319
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	2.17225
PMC9498168__F6a	PFOCR Pathway Figure Associations 2024	1.0	null
RAB9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06823
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PK-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP53BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36172
GTEX-NPJ8-2126-SM-3MJGK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OHPL-1026-SM-3MJGI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MJ-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56581
Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.43244
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911132
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42097
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31879
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42275
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25185
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30561
MOLM13	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28535
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39071
RH28	DepMap CRISPR Gene Dependency	1.0	2.01325
KDM5A	ENCODE Transcription Factor Targets	1.0	null
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5082
SNU1079	CCLE Cell Line Gene Expression Profiles	1.0	1.39102
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47812
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CW-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.8094
JOSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17368
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Aplasia/Hypoplasia Of The Eyebrow	DisGeNET Gene-Phenotype Associations	1.0	null
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06839
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45807
Hereditary retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
GSE116242_0_v_1_olig2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA2-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_10926_KO_Lis1_SRP126777	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.86307
SH3BP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08912
intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Autosomal recessive congenital ichthyosis 4A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56604
SLC16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6019
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0847
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hsa-miR-3182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
UBA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
Perturb_6118_KO_Fak_SRP279401	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.50905
Pigmented ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.146
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35478
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48016
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.305
Esophagus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1716
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24686
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33749
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20045
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.13847
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAT protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.009
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.14804
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUP-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907386
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01089
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
SUIT2	CCLE Cell Line Gene CNV Profiles	1.0	2.38118
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88033
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
retinal degeneration	GWASdb SNP-Disease Associations	1.0	0.412937
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52389
NCI-H1792 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
Sensory Perception	Reactome Pathways 2024	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05686
GTEX-Q2AI-0926-SM-48U1F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Retrosplenial area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81976
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37874
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67142
SKN	DepMap CRISPR Gene Dependency	1.0	2.02854
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897648
ZNF189	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19874
H2BC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08968
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.90456
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34552
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40777
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11425
glaucoma	GWASdb SNP-Disease Associations	1.0	1.29807
impaired skin barrier function	MGI Mouse Phenotype Associations 2023	1.0	null
PRKAR2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79562
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71632
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37987
GSE145215_2_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11252_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.40425
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
LAMTOR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76553
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428401
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48077
The canonical retinoid cycle in rods (twilight vision)	Reactome Pathways 2024	1.0	null
RNA nuclear export complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52416
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43446
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9434
Medial amygdalar nucleus, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01994
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.082119
Visual phototransduction	Reactome Pathways 2014	1.0	null
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5493
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258917
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59096
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75013
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073398
Hypotrichosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14111
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4934
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12906
REH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
eye disease	GWASdb SNP-Disease Associations	1.0	0.175862
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14554
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79562
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ribonuclease H2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
CHID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55783
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Meniere's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.08964
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29126
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.269
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50092
Perturb_10862_KO_Kdm5a_SRP257260	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.21388
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.974
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3333
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
UQCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67624
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01392
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063429
ORC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
Photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.972
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47327
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16484
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tou	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46363
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11508
PHETA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99854
hsa-miR-4443	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Vesiculobullous skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884127
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21573
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896002
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33017
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.038778
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85701
OECM-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11139
FMO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86776
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98208
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.963516
Chanarin-Dorfman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.701
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23009
PRRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13279
Acute promyelocytic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
VPS4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.2917
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
TFPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56228
MKN7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64418
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFJO-0626-SM-4LVMC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RBBP5	ENCODE Transcription Factor Targets	1.0	null
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.175862
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27188
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52744
Dehydration	DisGeNET Gene-Phenotype Associations	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TADA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40553
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248858_6_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88741
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.93
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51241
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057045
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.279367
GSE207914_3_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HO-1-N-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-449b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71855
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Icthyosis	DisGeNET Gene-Disease Associations	1.0	null
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12383
fetus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49341
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.8125
GDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50421
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.32187
Brain Lower Grade Glioma_LGG_TCGA-DU-6396-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Exodeoxyribonuclease V complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05513
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03248
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1555
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26353
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMYD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32446
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25448
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12712
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25366
PER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74954
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17213
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00772
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28585
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
DTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61969
CPXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8771
NAD(P)-binding domain	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.31656
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Regio oralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02826
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50127
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEP131	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2743
FGFR1OP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84381
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^3_None_GSE43302	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79603
Exfoliative Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
Dermal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
NCIH1355	CCLE Cell Line Gene CNV Profiles	1.0	1.61713
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052984
SJSA1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.45717
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.907455
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.834333
hsa-miR-4423-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4935
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23378
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51705
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04458
HS343T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59158
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900396
X-linked ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.042