association	dataset	threshold value	standardized value
KMS26	DepMap CRISPR Gene Dependency	1.0	2.12683
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893967
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31365
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845343
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37771
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893396
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_5535_KO_GOLGB1_ERP022243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
EHBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75593
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36155
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18206
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44097
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48283
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0741
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15095
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02705
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40307
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.78663
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52576
GTEX-RWS6-1326-SM-47JXB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19789
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07797
NCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94258
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.989314
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7847
GTEx Ovary 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	5.48207
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74357
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03638
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30055
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39356
KDM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25554
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963838
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64029
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.082
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93611
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.93589
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
Perturb_263_KO_GPX4_SRP255715	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53523
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02366
496100279_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09831
WDR46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42635
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90471
Perturb_10154_KD_ZRSR2_SRP265290	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.96856
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15713
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21832
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83134
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16033
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36063
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36384
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EPHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30507
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.948624
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01371
MSTO211H	DepMap CRISPR Gene Dependency	1.0	2.5413
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32798
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00352
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71245
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37385
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62274
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28234
KKU100	DepMap CRISPR Gene Dependency	1.0	4.25985
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.11203
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976154
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65307
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15951
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0214
NELFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35271
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23822
PSMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41353
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3425
HO-1-U-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45794
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU423	DepMap CRISPR Gene Dependency	1.0	3.4473
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3694
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAPPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99229
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52061
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	1.98903
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45823
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75078
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01728
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20388
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69502
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5006
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32911
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38416
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861185
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.52715
establishment of localization	GO Biological Process Annotations 2015	1.0	null
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	2.18168
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9945
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62863
RRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26082
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09275
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907541
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7828
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22391
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59471
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57526
Cellular retinaldehyde binding/alpha-tocopherol transport	InterPro Predicted Protein Domain Annotations	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.70733
chr22_30539442_C_G_b38	GTEx eQTL 2025	1.0	2.50394
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.24636
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56923
CCDC97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74449
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06556
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	1.57806
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.46745
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
EVX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51321
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36943
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49673
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19626
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40991
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41239
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907541
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69961
ARHGAP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06131
ARMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31622
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39075
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GRIK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49626
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	2.99448
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36645
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23309
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.40221
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03057
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03188
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8403
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26887
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36536
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7451
BTBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42798
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14892
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.700676
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PRRX2_PRRX2	Rummagene Transcription Factor Associations 2026	1.0	null
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44154
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83134
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2836
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32694
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49278
hsa-miR-4289	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09239
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15757
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859439
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951611
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02457
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84034
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
AFF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15571
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58525
Perturb_10148_KO_ASXL1_SRP251223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.4272
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903779
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
TFE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42128
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64546
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902983
ATP2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44382
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GTF2H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4971
PMC9927941-jci-133-163612-s046.xlsx-Sheet1-Table_S12_PAX5_expression_correlates_p_0_05_with_expression_of_126_of_the_other_T2D_DEGs_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-2726-SM-3NMAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31107
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983441
ZNF706	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38496
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12203
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5169
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2597
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9856
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17562
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32056
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11162
Apolipoprotein A1 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.35229
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7964
Perturb_12325_KD_CD274_SRP189203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83134
TASK1	DepMap CRISPR Gene Dependency	1.0	3.89825
GSE169152_5_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4779	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.92546
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63369
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.665188
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27485
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NXPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19256
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.86443
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.17659
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.88255
GRIN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64859
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1247
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21424
HEC251	DepMap CRISPR Gene Dependency	1.0	2.33296
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839032
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.953
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95623
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53999
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32121
ACADS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72714
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.837
Perturb_293_KO_GPX4_SRP255715	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.7212
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77891
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34702
RUNX1-22343733-KASUMI1-HUMAN-PERIPHBLOOD-AML	ChEA Transcription Factor Targets 2022	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958053
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24795
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01081
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93812
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42161
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87622
OVMIU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE239844_6_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T4C_BATF3_downreg_padj_0_01-Gene_Name_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
CXCL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90531
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.55733
DEPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30608
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72851
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902509
LPCAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6228
GIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07246
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987416
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.23784
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66835
MBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36463
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.873625
NP5	DepMap CRISPR Gene Dependency	1.0	11.7016
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01866
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82641
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95626
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870125
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31261
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF7L2_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851998
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20476
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.21227
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77866
WAPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83765
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.61268
SNU308	DepMap CRISPR Gene Dependency	1.0	2.22742
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
OVCAR-5	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31472
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966535
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47396
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58331
lung_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.32585
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02366
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25602
localization	GO Biological Process Annotations 2015	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8901_KD_STIM1_SRP128928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.93625
SNRPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28244
CRAL/TRIO, N-terminal domain	InterPro Predicted Protein Domain Annotations	1.0	null
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18948
SIN3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47431
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02732
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-2.26026
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25021
MT-ATP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24121
DHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73829
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24686
DEXI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07563
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67873
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.86116
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.82306
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880813
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29934
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19405
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830086
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61774
H3C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19499
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06069
CETN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78635
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19858
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ML-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
GTEX-X3Y1-2026-SM-3P5YM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.76584
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.855934
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90974
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10535
SPRY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42048
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867055
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6462
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827217
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02821
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33875
ZNF324B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18921
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.409
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917743
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41141
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4274
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25242
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17186
DDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2371
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907541
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03686
THOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49087
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6608
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02594
CEBPB	ENCODE Transcription Factor Targets	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98772
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831625
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12611
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09991
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840145
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58728
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872469
Creutzfeldt-Jakob disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0359
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17276
BT483	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35624
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.19192
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.30091
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74603
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2206
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.134
cell part	GO Cellular Component Annotations 2015	1.0	null
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
biological_process	GO Biological Process Annotations 2015	1.0	null
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995489
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02738
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38136
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0053
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5742
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64595
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839239
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1651
WM115	DepMap CRISPR Gene Dependency	1.0	3.78336
SLC43A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03193
ZNF319	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47293
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48347
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52543
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993391
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24715
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985275
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869213
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63412
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07656
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
USPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86245
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895576
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8391
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928637
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917319
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13546
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.16739
SCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93853
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990087
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.59779
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03683
PMC12036091-jcav16p2321s1.pdf-10-E2F7_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18108
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.890635
TSNAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95638
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9704
ZCCHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08754
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86247
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922979
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49106
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48031
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1435
cellular_component	GO Cellular Component Annotations 2015	1.0	null
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07934
Prion disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
PSMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06064
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66276
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.945963
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850844
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851514
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78377
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14892
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	0.851868
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95053
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21167
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0347
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915425
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
DETROIT562	DepMap CRISPR Gene Dependency	1.0	2.05895
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08988
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09275
SW1271	DepMap CRISPR Gene Dependency	1.0	3.54877
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994428
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965795
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83134
NB7	DepMap CRISPR Gene Dependency	1.0	3.85484
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870408
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848566
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18454
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07634
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39155
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09239
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31472
INTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15183
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19117
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06984
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-325-TCF7L1_TCF7L1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.802703
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.109
AP-4	MotifMap Predicted Transcription Factor Targets	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43223
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.54621
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.761
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21198
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895749
PMC7576810-41419_2020_3099_MOESM9_ESM.xlsx-MS_analysis_EVI1-WT_vs_EVI1-S43-Unnamed_0_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9172
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7754
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4633
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7392
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02457
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0915
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944296
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0675
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB5_CREB5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15604
FAM98B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63766
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02676
18537972-TableS4	GeneSigDB Published Gene Signatures	1.0	null
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29758
SLR24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35649
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89304
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35209
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.809
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36721
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17245
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907865
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LUDLU1	DepMap CRISPR Gene Dependency	1.0	3.60758
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8302
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.614
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.5294
OCUM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93106
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955108
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5975
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2559
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16436
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.019
PRMT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86547
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.985275
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
SKGI	DepMap CRISPR Gene Dependency	1.0	2.20361
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44401
RXRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22907
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33765
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12841
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898645
GOLD	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857282
transport	GO Biological Process Annotations 2015	1.0	null
496100591_TCx_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14041
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.999756
SYDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07959
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.521
TMEM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28019
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09593
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6957
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17264
gallbladder_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.977321
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01678
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25245
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850582
PMC9927941-jci-133-163612-s045.xlsx-Sheet1-Table_S11_DEGs_with_a_PAX5_binding_motif_as_identified_by_Pscan_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
LCAM1	DepMap CRISPR Gene Dependency	1.0	2.41278
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01332
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1509
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826355
HES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43053
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11587
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.75896
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881341
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.873678
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36262
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847134
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93509
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39762
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53528
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18484
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02622
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58728
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63055
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932969
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881642
NANOGP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52743
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7498
XRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5436
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	3.00388
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lung	HPA Tissue Gene Expression Profiles	1.0	1.26547
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.825972
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863445
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834941
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.897992
RPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99226
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52159
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26912
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46349
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13965
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42515
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.829319
GSTZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22583
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42466
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.975917
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959652
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840451
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5526
PATU8988T	DepMap CRISPR Gene Dependency	1.0	3.84077
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14079
BNIP3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42733
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976154
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.26033
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52576
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31221
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.63383
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52969
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
LN18	DepMap CRISPR Gene Dependency	1.0	2.88916
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCNO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0188
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884153
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32679
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57879
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84351
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98136
ACTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09276
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	3.35699
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8355
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77645
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.9174
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966535
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963007
Lewis lung carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TGOLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63962
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62905
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59476
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13772
CRLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19272
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.08665
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861185
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22694
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6486
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923044
TTC642	DepMap CRISPR Gene Dependency	1.0	5.18142
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885314
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.20568
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17533
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.793831
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65209
ZBED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69256
GTEx Ovary 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	5.64589
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83044
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24018
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40856
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833842
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49064
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	1.55349
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
FUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87164
chr22_30503367_C_T_b38	GTEx eQTL 2025	1.0	2.84275
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2334
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74291
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980564
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869213
HS939-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-LHX2_LHX2	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02384
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11341
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3097
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43123
MDA-MB-415	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE239844_6_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUZC-0926-SM-4BOQF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19438
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09275
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954396
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15759
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09703
MFE280	DepMap CRISPR Gene Dependency	1.0	3.18885
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CACNG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00305
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7096
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07441
A1207	CCLE Cell Line Gene CNV Profiles	1.0	1.42272
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03596
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64827
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911452
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11702
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FUNDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82059
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37499
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23822
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.71059
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938587
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35206
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72138
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82698
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89672
PLXNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92823
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28593
fat_a.V1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854284
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19564
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34565
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04327
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.58568
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40822
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54076
lung_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.0587
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59869
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1568
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	1.35641
KP-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08275
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2983
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58728
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.633
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98092
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98816
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.77151
PMC11442894-41467_2024_52678_MOESM5_ESM.xlsx-all_MSC_vs_iMPC-Unnamed_0_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33143
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10173
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2416
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6875
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00194
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50712
KALS1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.18731
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE102870_11_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949524
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29359
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.760561
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867461
OCUBM	DepMap CRISPR Gene Dependency	1.0	3.13704
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01648
RNF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39708
HUO-3N1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14787
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44136
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3333
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.342
LS	DepMap CRISPR Gene Dependency	1.0	3.81099
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01215
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46349
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56052
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ZNHIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2743
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71199
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14892
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931941
L363	DepMap CRISPR Gene Dependency	1.0	2.48637
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26109
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09275
AU565	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8957
GSE118077_1_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.38638
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98772
EPRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40617
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37779
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837713
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	2.16757
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56009
WDTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22568
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8451
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08229
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897891
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845462
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51062
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06243
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903779
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892442
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	1.43302
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03687
PMC4021073-1471-2407-14-278-S4.xlsx-Sheet1-Supplementary_Table_S5_Genes_with_GATA3_ChIP-seq_peak_within_10kb_from_transcription_start_site_TSS_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.718
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79145
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839032
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87179
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37563
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825467
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956004
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02382
TKKK	DepMap CRISPR Gene Dependency	1.0	4.30531
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0545
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	1.83568
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15123
PANC0203	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41968
MAZ	ENCODE Transcription Factor Targets	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
PHKG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4401
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	5.85607
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36394
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895245
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56062
GARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977062
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.864471
TE-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83134
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972024
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72658
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45688
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53583
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24325
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8809
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21167
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44984
HS578T	CCLE Cell Line Gene CNV Profiles	1.0	1.39989
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98645
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.00326
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24524
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.62532
ZNF420	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13906
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74728
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.785
DUSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76436
GTEX-QLQW-1126-SM-2S1Q8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91481
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88456
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06868
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59232
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22606
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TCF21_TCF21	Rummagene Transcription Factor Associations 2026	1.0	null
NPPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09419
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15713
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02457
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.09741
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36924
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5857
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04687
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.892872
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.59208
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62987
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-2.05336
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46363
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0025
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28965
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC0203	DepMap CRISPR Gene Dependency	1.0	13.9162
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10011
intracellular	GO Cellular Component Annotations 2015	1.0	null
RBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86397
GSE160304,GSE163392_7_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NAGPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1724
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	1.46389
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876778
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
CLEC14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26651
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932993
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	2.93442
transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18619
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67009
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3117
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFSD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12876
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58728
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89471
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40571
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43748
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8048
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99969
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09499
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10452
ZNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56121
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984625
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47458
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05287
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8818
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01228
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919479
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25363
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05066
GOLT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24781
HELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.059
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.56706
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831901
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833531
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21445
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56519
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83482
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00486
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48211
496100507_FWM_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34699
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878218
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03683
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02366
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.78788
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27297
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52545
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5359
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38662
kidney	HPA Tissue Gene Expression Profiles	1.0	0.988707
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6649
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11476
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840391
Perturb_12265_KD_PUS1_SRP394042	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.32234
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67793
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19515
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940319
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33001
QDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21212
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9788
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.25427
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-0126-SM-2TC5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865166
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75728
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02457
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24817
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20524
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83044
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2936
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00169
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61126
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
NCIH526	DepMap CRISPR Gene Dependency	1.0	7.09492
Perturb_8500_OE_RAS_SRP150620	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.2614
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73756
DDX24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.06194
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09314
SW837	DepMap CRISPR Gene Dependency	1.0	6.70348
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69509
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6932
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04224
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1032
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.81502
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77392
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990372
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
MBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04878
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03541
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04044
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.44155
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891078
LGALSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1227
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3382
POLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62631
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07708
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6797
ZDHHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48274
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.13892
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12452
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5981
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.91426
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1341
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.38
COV644	CCLE Cell Line Gene CNV Profiles	-1.0	-2.21292
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87227
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853977
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71637
KNS42	CCLE Cell Line Gene CNV Profiles	1.0	2.58007
CRAL-TRIO domain	InterPro Predicted Protein Domain Annotations	1.0	null
RERFLCAD2	DepMap CRISPR Gene Dependency	1.0	3.38016
Perturb_12326_KD_CD274_SRP189203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SSC4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72722
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41968
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2268
fat_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.31816
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ICAM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41255
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11418
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1576
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
WM983B	DepMap CRISPR Gene Dependency	1.0	3.62003
ZBTB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91033
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.930247
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913073
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EPS8L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04204
EZH2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4752	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907541
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972912
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913291
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39092
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50541
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.81611
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25242
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86609
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969205
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.760561
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19978
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37536
METRNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11368
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44385
OCI-AML3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Intracranial berry aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
TRIM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82309
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837741
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3571
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48513
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12802
GSE140322_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50274
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21535
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49916
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59659
ATXN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82167
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2185
molecular_function	GO Molecular Function Annotations 2015	1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.875
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18395
ZBTB49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58739
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07446
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927275
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.924769
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100287_TCx_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07018
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910036
EMC-BAC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966535
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83917
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15604
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32122
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34646
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57072
PEO4	DepMap CRISPR Gene Dependency	1.0	2.84248
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44919
NCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95517
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02758
MOLP-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1272
NRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66717
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1413
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	1.63569
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14174
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17987
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892246
PSMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62225
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96137
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0021