association	dataset	threshold value	standardized value
MESP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13206
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1529
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34982
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.69
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61098
Intercellular bridge	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.152
Cortical microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.197
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97157
PPP4R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99914
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2012
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
Axoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
SNU16	DepMap CRISPR Gene Dependency	1.0	3.67556
GSE198165,GSE198166_5_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0992
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2145
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.602
neuron projection	GO Cellular Component Annotations 2023	1.0	null
Exocyst	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
HSC2	DepMap CRISPR Gene Dependency	1.0	2.95341
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38943
L1TD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13293
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7464
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.69357
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.70905
axon	GO Cellular Component Annotations 2023	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4029
FBXL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93405
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13481
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43476
Serine deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	151.656
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
IMR32	DepMap CRISPR Gene Dependency	1.0	2.20963
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77489
GSE212893_2_v_3_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0283
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5939
Organellar small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
ZNF300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86258
USP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27752
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
Reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6879
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8789
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6573
RBM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19595
Salivary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
496100636_FWM_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.17304
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2514
RNF130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19453
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.215
Septin complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80977
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32121
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
LIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8098
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57168
COPG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92505
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76581
SPTY2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78526
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
Angiocentric glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
RAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17238
PABPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72263
KLC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85579
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
CNOT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43729
flyrd18	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05141
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3502
spermatid development	GO Biological Process Annotations 2023	1.0	null
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Supratentorial ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.54
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4973
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9116
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SCC-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.564
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.504
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitotic actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.21575
Cytoplasmic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.196
GRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77852
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4658
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12959
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93614
Cauda epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.3862
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
Septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.235
CSTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42776
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
Familial isolated trichomegaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Congenital fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RPMI8226	DepMap CRISPR Gene Dependency	1.0	4.1173
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2823
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0289
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6136
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94666
Adenoid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62891
SCAPER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34021
GOLT1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24781
Cell cortex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HS683	DepMap CRISPR Gene Dependency	1.0	2.29675
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
IFIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15877
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
MTREX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1884
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3182
Salivary gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
RAB2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38721
Intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
decreased hematocrit	MGI Mouse Phenotype Associations 2023	1.0	null
GP5D	DepMap CRISPR Gene Dependency	1.0	2.23375
MFSD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06264
p190	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32989
UBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00102
SLC26A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18956
Glioma stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64226
TRIM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6881
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
Dendrite	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3232
Rasheedsarcomavirus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
ZNF292	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5185
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Phycobiont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.019
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6433
GSE131649_4_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LPGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83651
FAM32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06535
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8691
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85669
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DMRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.10364
ETNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84148
TRIM71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16946
C17orf75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48651
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
axon	GO Cellular Component Annotations 2025	1.0	null
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
KYSE30	DepMap CRISPR Gene Dependency	1.0	3.69015
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36244
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BARX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06207
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.2684
TENT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07044
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
ZNF607	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63114
Serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.926
Ciliary base	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.667
496100645_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06948
Cellular bud neck contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.955
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
CCDC177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11927
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8708
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
acrosomal vesicle	GO Cellular Component Annotations 2023	1.0	null
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	136.693
cataract	MGI Mouse Phenotype Associations 2023	1.0	null
Anaplastic astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82072
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7923
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78605
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Giant Cell Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
KCTD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50772
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.1433
Female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25092
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5261
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3614
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77849
Cerebrum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
Serum Albumin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
PMC11003700-pbio.3002240.s011.xlsx-MYCN-IMR32_RawData-Unnamed_2_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
decreased mean corpuscular volume	IMPC Knockout Mouse Phenotypes	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Contractile actin filament bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.338
DYNLT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39557
DOLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23042
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.71625
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9543
ZBTB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2294
MZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37816
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36886
Internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
127399	DepMap CRISPR Gene Dependency	1.0	2.35875
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2139
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4144
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
PK-15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Salivary gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41321
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5652
KM12	DepMap CRISPR Gene Dependency	1.0	2.29149
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7949
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6354
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.2742
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.733
High grade ependymoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Embryonic cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91655
ABCG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51013
ATRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23604
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94477
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2553
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0911
CCLP1	DepMap CRISPR Gene Dependency	1.0	2.08539
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32097
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79393
Plasma free amino acid levels (adjusted for twenty other PFAAs)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.83979
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6268
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
ARL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05959
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47101
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
TGBC52TKB	DepMap CRISPR Gene Dependency	1.0	3.86164
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6715
Motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.315
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2021
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12029
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51246
KIRREL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98426
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.725
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9508
CHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4215
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2534
MIXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46013
decreased hematocrit	IMPC Knockout Mouse Phenotypes	1.0	null
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
Proneural glioma stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
NFIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09165
Cellular bud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.195
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7458
Somatodendritic compartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZMAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71306
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6364
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1284
Endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2296
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.083
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1878
Axon	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Cleavage furrow	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.053
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.7354
DAZAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89667
septin ring	GO Cellular Component Annotations 2025	1.0	null
Cardiac microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2228
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Cell division site	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2718
Sperm head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.783
APOBEC3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
PECAPJ41CLONED2	DepMap CRISPR Gene Dependency	1.0	2.53581
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44938
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89114
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41798
PCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39696
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3586
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4499
Septin collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.55
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0876
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78723
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
Hidradenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
increased circulating aspartate transaminase level	MGI Mouse Phenotype Associations 2023	1.0	null
496100621_TCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.5999
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chronic myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Acrosomal vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
cataract	IMPC Knockout Mouse Phenotypes	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3509
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57829
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53629
FAM110C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00903
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14686
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8427
CCDC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37958
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
NOSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58368
RIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08263
DUSP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79176
CRTC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17029
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80597
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38439
ICC8	DepMap CRISPR Gene Dependency	1.0	2.26461
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56682
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62788
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
CCNJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7922
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.887
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68006
TMEM200A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52091
cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3821
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4574
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.233
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09008
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83248
MAD2L1BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41738
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82821
neuron migration	GO Biological Process Annotations 2023	1.0	null
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
TMEM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01882
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3254
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12685
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7647
PDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4033
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
g/g	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
SEMK2	DepMap CRISPR Gene Dependency	1.0	2.73143
HOXB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86489
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
Gliosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
496100579_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16276
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.4316
Actin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.625
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1023
CTXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51411
PTP4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26814
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1683
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4803
GSE181003_3_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
SF126	DepMap CRISPR Gene Dependency	1.0	2.60754
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99777
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.854
BA/F3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.031
GSE199899_4_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5611
LHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60777
PLAUR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60212
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8973
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65879
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73998
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
H2AB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58716
LIMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24428
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.184
GSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19873
FAM236B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47945
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0536
Central nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.552
Childhood fibrosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73669
Medulloblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
Axonemal central pair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.511
ZNF165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
microtubule cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
Colorectal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
HCC461	DepMap CRISPR Gene Dependency	1.0	2.70615
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0213
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2596
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27614
Pleomorphic xanthoastrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99115
AP-3 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
GSE153907,GSE153908_0_v_1_azathioprine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6423
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52974
KMS27	DepMap CRISPR Gene Dependency	1.0	2.03465
Childhood oligodendroglioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32669
Cortical microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.017
TOV112D	DepMap CRISPR Gene Dependency	1.0	4.69995
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.891
9+0 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11103
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4786
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.0435
ZNF587B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46631
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
IPO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22091
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5803
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
Plant collar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12465
dendrite	GO Cellular Component Annotations 2025	1.0	null
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31571
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6142
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Rat-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
KIJK	DepMap CRISPR Gene Dependency	1.0	2.52209
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7635
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
Midbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.407
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79335
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05281
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61347
Sperm flagellum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.604
generation of neurons	GO Biological Process Annotations 2023	1.0	null
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03587
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68678
Cell division site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.634
IDH-wildtype glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90997
Cellular bud neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86488
Cortical layer of collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.902
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
increased circulating alanine transaminase level	IMPC Knockout Mouse Phenotypes	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.597
PRRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69979
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
GTPase activity	GO Molecular Function Annotations 2025	1.0	null
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9071
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0813
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60056
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6789
cytoskeleton-dependent cytokinesis	GO Biological Process Annotations 2025	1.0	null
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
ZNF800	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92847
Supratentorial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
LS	DepMap CRISPR Gene Dependency	1.0	2.58291
Meiotic septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
DMS53	DepMap CRISPR Gene Dependency	1.0	2.1684
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52199
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66148
Embryonal testis carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9011
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
Macular telangiectasia type 2	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49104
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0569
CAL27	DepMap CRISPR Gene Dependency	1.0	2.50532
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.083
SSTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42923
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2389
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.963
ETV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61466
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55711
Cleavage apparatus septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.279
protein localization to perinuclear region of cytoplasm	GO Biological Process Annotations 2023	1.0	null
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80875
NCIH441	DepMap CRISPR Gene Dependency	1.0	3.19858
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1591
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Axonemal microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
SKGI	DepMap CRISPR Gene Dependency	1.0	2.08267
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.6209
Pilomyxoid astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57659
496100599_TCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00285
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.705
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11888
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2043
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.19684
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78852
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4703
protein localization	GO Biological Process Annotations 2023	1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8732
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.153
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75418
Amyotrophic neuralgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.39
MYSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15671
Split septin rings	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.161
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0337
Plant crown	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21869
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SH2D2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14153
TSC22D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27262
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00846
PTEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77463
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
increased circulating aspartate transaminase level	IMPC Knockout Mouse Phenotypes	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0032
neuron projection	GO Cellular Component Annotations 2025	1.0	null
CHPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76109
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37979
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0272
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8362
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3277
WSB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42476
enhanced passive avoidance behavior	MGI Mouse Phenotype Associations 2023	1.0	null
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mitotic spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.337
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40874
BOLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48403
KCNAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.79927
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
NCIH1975	DepMap CRISPR Gene Dependency	1.0	4.86987
Ciliary plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73732
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39927
REX1BD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22738
Spermatozoon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
SLC44A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90578
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6839
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90845
Nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
CRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12061
GSE112763,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1641
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9176
PSPH deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.19
POU2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72606
Diffuse astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0951
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8419
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
Opioid use cessation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
GSE93918_1_v_3_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07647
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06907
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.833
GSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38134
MVB12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38688
septin cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2306
496100573_HIP_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.74859
MBLAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18039
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.0352
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoskeleton-dependent cytokinesis	GO Biological Process Annotations 2023	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.3
Mucoepidermoid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
MYBPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83288
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.724
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.8271
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.1908
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
UBLC1	DepMap CRISPR Gene Dependency	1.0	4.84641
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.24061
Parotid gland duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Acinar cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6671
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.612
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.76271
GSE157684,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6744
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4302
SIRT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80081
UHO1	DepMap CRISPR Gene Dependency	1.0	2.21039
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12934
ZFP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48938
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9507
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
Gliosarcoma	DisGeNET Gene-Disease Associations	1.0	null
septin cytoskeleton	GO Cellular Component Annotations 2023	1.0	null
Brachial plexus neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.205
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6207
DNAJC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4598
CDC14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12846
protein localization	GO Biological Process Annotations 2025	1.0	null
Abscission zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
MIOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54914
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Spermatogenic failure 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9716
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1937
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69716
increased circulating alanine transaminase level	MGI Mouse Phenotype Associations 2023	1.0	null
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49488
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
C14orf28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37053
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.61
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9364
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8696
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64712
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
ICC2	DepMap CRISPR Gene Dependency	1.0	2.00842
PIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40797
U251MG	DepMap CRISPR Gene Dependency	1.0	2.45349
GSE196117_1_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6198
Dendritic tree	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3248
MECOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28401
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.6145
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3436
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91732
Perikaryon	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
nt2d1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8507
JPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.507
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76019
Spindle pole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.103
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4212
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.21
ITM2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73008
OSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
TCAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3447
septin ring	GO Cellular Component Annotations 2023	1.0	null
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6627
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7854
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08153
increased mean corpuscular hemoglobin concentration	MGI Mouse Phenotype Associations 2023	1.0	null
Septin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.583
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7827
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30907
KMS34	DepMap CRISPR Gene Dependency	1.0	2.23514
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5225
Cerebral ventricle cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
decreased mean corpuscular volume	MGI Mouse Phenotype Associations 2023	1.0	null
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.683
ATXN7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36515
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4826
WDR45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49866
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8879
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
TRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7268
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30726
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
Infratentorial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
DHX58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5791
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
NDUFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58059
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4832
GSE160373_6_v_4_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMCH1	DepMap CRISPR Gene Dependency	1.0	2.60018
MORF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34164
Low grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4739
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24113
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3872
CD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7503
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34827
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88507
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9267
Alanine transaminase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46363
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
Manchette	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.765
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.554
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8537
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4234
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6033
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0743
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53666
ZNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79497
BHLHE40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28463
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2381
Pilocytic astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2491
ZNF506	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4353
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27595
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
Mesenchymal glioma stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
PIWIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04908
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0979
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11981
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
Contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.718
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.738
SAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5956
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48836
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
UBE2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27914
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
microtubule cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51071
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82826
Annuli extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5833
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.694
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3284
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
SEM	DepMap CRISPR Gene Dependency	1.0	3.42406
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Appendicular lean mass	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.5699
increased neuronal stem cell self-renewal	MGI Mouse Phenotype Associations 2023	1.0	null
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1952
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fibrolamellar carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
PMC10789969-crt-2023-577-Supplementary-Table-S2.pdf-5-ZNF181_ZNF181	Rummagene Transcription Factor Associations 2026	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0727
STBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78429
NDUFB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47722
TE-03 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PTDSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85252
OE21	DepMap CRISPR Gene Dependency	1.0	2.65992
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8214
SOCS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09541
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1697
NR0B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40142
GSE240809_0_v_1_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
acrosomal vesicle	GO Cellular Component Annotations 2025	1.0	null
Mitochondrial small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
Cellular bud neck septin structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.279
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
GSE216043_10_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.1128
Cellular bud neck septin ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.279
ZNF235	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43123
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.0134
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30515
Filament	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.019
ANKRD13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33042
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4167
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.052
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
GTPase activity	GO Molecular Function Annotations 2023	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital mesoblastic nephroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
NAA30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39218
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.746
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0065
ASPC1	DepMap CRISPR Gene Dependency	1.0	2.31039
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9113
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17772
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
Collagen and cuticulin-based cuticle extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.992
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
LK2	DepMap CRISPR Gene Dependency	1.0	2.55465
PRRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.246
Gin4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.279
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
LMX1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52934
ELF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11084
Stamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.007
Neuronal cell body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
Septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.571
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4219
Septin cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
MAC2A	DepMap CRISPR Gene Dependency	1.0	3.22997
impaired cued conditioning behavior	MGI Mouse Phenotype Associations 2023	1.0	null
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47552
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4422
EEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67512
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoskeleton	GO Cellular Component Annotations 2025	1.0	null
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
PIK3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
dendrite	GO Cellular Component Annotations 2023	1.0	null
spermatid development	GO Biological Process Annotations 2025	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.124
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.603
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4988
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9408
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6923
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6569
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKNFI	DepMap CRISPR Gene Dependency	1.0	3.19318
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6693
DGKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0668
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PNPLA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01115
Breast secretory carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.417
MARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97497
H3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23516
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15396
GSE130715_2_v_3_budesonide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6573
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
1306 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.375
Acute myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COMMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37789
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.899
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48509
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56531
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.079
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10373
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.258
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
TUHR10TKB	DepMap CRISPR Gene Dependency	1.0	3.63404
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
SCRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52449
MLLT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89275
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GSE207914_3_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8055
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
increased thigmotaxis	MGI Mouse Phenotype Associations 2023	1.0	null
HOMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96136
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86119
ZIC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12611
GSE135514_2_v_7_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LDLRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54042
Sporulating cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
Extraocular retinoblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
Sperm annulus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.262
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7877
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8283
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3962
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8548
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92351
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17405
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3737
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8163
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6238
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5371
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51978
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
KIAA0040	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78191
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9583
SLITRK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87964
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87641
increased mean corpuscular hemoglobin concentration	IMPC Knockout Mouse Phenotypes	1.0	null
RAB9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
Mammary analogue secretory carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26628
Myxosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.388
Outer dense fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26126
PACADD137	DepMap CRISPR Gene Dependency	1.0	2.01331
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69208
Cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.694
NT2/D1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.129
ECC2	DepMap CRISPR Gene Dependency	1.0	2.65633
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28648
CCDC88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52977
Septin ring	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6775
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
ST486	DepMap CRISPR Gene Dependency	1.0	2.606
neuron migration	GO Biological Process Annotations 2025	1.0	null
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.41302
RNF144A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61713
Spinal cord disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
ARID5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50364
SLC2A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47509
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37212
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.083
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
SUPM2	DepMap CRISPR Gene Dependency	1.0	2.45133
VKORC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69721
RPUSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10643
GLUD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10469
protein localization to perinuclear region of cytoplasm	GO Biological Process Annotations 2025	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
PNRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09139
GSE196117_6_v_5_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6885
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC827	DepMap CRISPR Gene Dependency	1.0	3.47327
LS180	DepMap CRISPR Gene Dependency	1.0	2.11322
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91069
ERBB4-EGFR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.051
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.0856
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60049
Mitotic septin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00505
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC38	DepMap CRISPR Gene Dependency	1.0	2.85943
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1038
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
GSE198165,GSE198166_5_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6267
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
Myosin II complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.278
generation of neurons	GO Biological Process Annotations 2025	1.0	null
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17429
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67258
GSE147669_2_v_1_tram2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.171
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.067
Male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.067
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
Childhood low-grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2025	1.0	null
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30069
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26083
IFFO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40232
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1865
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Mitotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.379
Cell body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62361
TBL1XR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46647
Colorectal adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
Oligodendroglioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Giant cell glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
ribonucleoside triphosphate phosphatase activity	GO Molecular Function Annotations 2023	1.0	null
RAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50784
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.347
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84448
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
CTAGE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34157
HK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26619
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4456
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
SELENOO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48604
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2669
Male infertility due to globozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2963
Plastron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
Plasma free amino acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.60458
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98841