association	dataset	threshold value	standardized value
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7462
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11047
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3296
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2546
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.81361
A704	CCLE Cell Line Gene Expression Profiles	1.0	1.74302
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11138
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43144
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRKCA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMC6	Pathway Commons Protein-Protein Interactions	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.3128
MES-SA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HIST1H4F	Pathway Commons Protein-Protein Interactions	1.0	null
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10079688-41467_2023_37633_MOESM7_ESM.xlsx-IP_JUN_in_WT_vs_sgJUN_cells-Supplementary_Data_4_List_of_interactors_of_JUN_identified_by_label-free_quantitative_proteomics_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
COV318	CCLE Cell Line Gene Expression Profiles	1.0	2.10632
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052967
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957201
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3615
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-0.865416
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0445
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.904266
regulation of protein catabolic process	GO Biological Process Annotations 2023	1.0	null
PRPF6	Pathway Commons Protein-Protein Interactions	1.0	null
SF3B4	Pathway Commons Protein-Protein Interactions	1.0	null
496100578_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5084
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
KRT16	Pathway Commons Protein-Protein Interactions	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49915
HH	CCLE Cell Line Gene Expression Profiles	1.0	1.61929
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5926
NCIH2126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90577
MVP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-A4WN-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARK4	Pathway Commons Protein-Protein Interactions	1.0	null
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39417
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13692
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94029
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2853
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iron-sulfur cluster transfer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3156
RPA2	Pathway Commons Protein-Protein Interactions	1.0	null
MM1S	Achilles Cell Line Gene Essentiality Profiles	1.0	1.39092
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94766
Interphotoreceptor matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.902
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24486
RBBP5	ENCODE Transcription Factor Targets	1.0	null
TMEM245	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92241
STK3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr18_63581754_C_T_b38	GTEx eQTL 2025	1.0	1.58052
superficial stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00105
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
KYSE270	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51675
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26057
Bronchial epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
DSP	Pathway Commons Protein-Protein Interactions	1.0	null
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-7774-01A-21R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KLB	Pathway Commons Protein-Protein Interactions	1.0	null
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21101
KRT8	Pathway Commons Protein-Protein Interactions	1.0	null
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67123
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.26867
KRT77	Pathway Commons Protein-Protein Interactions	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051677
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056788
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.006729
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16526
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9464213-41467_2022_33063_MOESM9_ESM.xlsx-BNC2_proteins-gene_name_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.992712
RCM1	DepMap CRISPR Gene Dependency	1.0	2.10303
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP2M1	Pathway Commons Protein-Protein Interactions	1.0	null
SNRPA1	Pathway Commons Protein-Protein Interactions	1.0	null
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01298
Perturb_17409_KO_Kat7_SRP346204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.68373
PMC11657369-12951_2024_3025_MOESM2_ESM.xlsx-C4-2ENZR-NR2F1-AS1-pulldown-Gene_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
RUVBL1	Pathway Commons Protein-Protein Interactions	1.0	null
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSK3A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223008_9_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNRPE	Pathway Commons Protein-Protein Interactions	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38668
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03506
Follicular stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
FEM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21144
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.79026
Perturb_14411_KO_Cnot6/Cnot6L_SRP285826	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.18989
GSE131903_0_v_2_abca12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Inguinal canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
Arid3b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5504
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-0.785405
NACAP1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5362_KO_Dux_SRP237568	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.48121
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
endopeptidase regulator activity	GO Molecular Function Annotations 2015	1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.36817
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11717
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
SERPINF2	Pathway Commons Protein-Protein Interactions	1.0	null
YWHAG	Pathway Commons Protein-Protein Interactions	1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4305
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07161
ZNF831	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65867
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39894
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055804
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864394
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U343	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.1101
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.62484
VMRCRCW	CCLE Cell Line Gene Expression Profiles	1.0	2.19076
GNL3	Pathway Commons Protein-Protein Interactions	1.0	null
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21622
RARS	Pathway Commons Protein-Protein Interactions	1.0	null
ficolin-1-rich granule membrane	GO Cellular Component Annotations 2023	1.0	null
cell differentiation	GO Biological Process Annotations 2015	1.0	null
ZCCHC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55038
polymorph layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5678
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08517
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.89678
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.989221
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70448
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.586
superficial stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44041
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GATA2	ChEA Transcription Factor Targets	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8931
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	4.95163
HCC1395	CCLE Cell Line Gene CNV Profiles	-1.0	-1.434
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825725
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982196
negative regulation of protein metabolic process	GO Biological Process Annotations 2023	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78291
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0948
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
superficial stratum of VPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0155
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MARK2	Pathway Commons Protein-Protein Interactions	1.0	null
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42648
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5411
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A460-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFE2-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17837
ficolin-1-rich granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
NONO	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RX-A8JQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QARS	Pathway Commons Protein-Protein Interactions	1.0	null
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
Rheumatoid arthritis disease specific fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
RARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98139
MAFK	ENCODE Transcription Factor Targets	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054098
Shell gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
UMRC6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.66735
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85745
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61295
HDAC6	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4986-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.2516
intermediate part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00266
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926578
binding	GO Molecular Function Annotations 2015	1.0	null
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6344081-elife-40364-supp5.xlsx-PLZF_peaks_H3K27Ac_unchanged-Unnamed_10_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40935
GNB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71648
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-5869-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2259
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36306
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01918
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.2137
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEL9217	DepMap CRISPR Gene Dependency	1.0	3.28198
RPS6KA4	Pathway Commons Protein-Protein Interactions	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959874
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.15218
Lung adenocarcinoma_LUAD_TCGA-78-7536-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.93769
D-542MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPR	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H5-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56343
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02805
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180631_1_v_0_yap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3618
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.53163
EIF3B	Pathway Commons Protein-Protein Interactions	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0722
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958605
JAK2_knockout_79_GSE26188	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78755
TNK1	Pathway Commons Protein-Protein Interactions	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918572
biological_process	GO Biological Process Annotations 2015	1.0	null
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20531
EEF1D	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8098-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967928
H3118	DepMap CRISPR Gene Dependency	1.0	3.08216
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2521
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29748
GOLGB1	Pathway Commons Protein-Protein Interactions	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.996407
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10078
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957201
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857655
Brain Lower Grade Glioma_LGG_TCGA-DB-A64V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56124
vesicle	GO Cellular Component Annotations 2015	1.0	null
PRKAB1	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0806
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18811
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
developmental process	GO Biological Process Annotations 2015	1.0	null
BT-483	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29421
gonad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22415
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	5.09467
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.7298
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.2281
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052898
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1006
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13402
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47
PMC12405659-CTM2-15-e70437-s001.xlsx-Supplementary_Table_5-BioGrid-interaction_protein_with_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
MLMA	COSMIC Cell Line Gene CNV Profiles	1.0	2.09431
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.34023
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
negative regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
RPA3	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85583
SMC4	Pathway Commons Protein-Protein Interactions	1.0	null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
17426248-TableS2b	GeneSigDB Published Gene Signatures	1.0	null
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
RPL30	Pathway Commons Protein-Protein Interactions	1.0	null
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79025
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12763
BL480 (UBE3A)	NURSA Protein Complexes	1.0	null
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06249
PKM	Pathway Commons Protein-Protein Interactions	1.0	null
RPA1	Pathway Commons Protein-Protein Interactions	1.0	null
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39416
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.446
Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58765
HSC3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48763
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
ENDOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5815
TUBB3	Pathway Commons Protein-Protein Interactions	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.81
HRNR	Pathway Commons Protein-Protein Interactions	1.0	null
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5459
LS411N	Achilles Cell Line Gene Essentiality Profiles	1.0	2.04824
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49094
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918485
DYNC1LI2	Pathway Commons Protein-Protein Interactions	1.0	null
endopeptidase inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BL3453 (ZWINT)	NURSA Protein Complexes	1.0	null
RPL17	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831995
SNRPB2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7886351-elife-65905-supp3.xlsx-Supplementary_file_3a-MYB_IP-MS_protein_lists_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
KRT17	Pathway Commons Protein-Protein Interactions	1.0	null
AZI2	Pathway Commons Protein-Protein Interactions	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32001
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-1.94835
DYNLL1	Pathway Commons Protein-Protein Interactions	1.0	null
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04794
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47355
RCOR1	ChEA Transcription Factor Targets	1.0	null
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
Postsubiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12661
Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.13007
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19836
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32923
testis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243918
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
GAPDH	Pathway Commons Protein-Protein Interactions	1.0	null
SNU1077	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47545
collagen-containing extracellular matrix	GO Cellular Component Annotations 2025	1.0	null
TOV-112D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
thiamine_rattus norvegicus_gpl2896_gse19292	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPL27	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05942
G140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07208
A375SKINCJ3	DepMap CRISPR Gene Dependency	1.0	6.30573
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.72649
PMC6424098-mmc5.xlsx-CEBP_Binder-Gene_names_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
tertiary granule	GO Cellular Component Annotations 2025	1.0	null
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90568
CAMKK2	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF326	Pathway Commons Protein-Protein Interactions	1.0	null
RPS20	Pathway Commons Protein-Protein Interactions	1.0	null
SERBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSK3B	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3000-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	5.01722
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10279
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNB19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34391
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39199
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tachycardia_Myocardial tissue_GSE7999	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.57937
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1989
MDAMB361	DepMap CRISPR Gene Dependency	1.0	3.31809
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35718
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.676
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK8	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_control-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53023
ACTL6A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62834
Ovarian surface epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.39516
Sarcoma_SARC_TCGA-DX-A1KU-01A-32R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11657369-12951_2024_3025_MOESM2_ESM.xlsx-PC-3-NR2F1-AS1-pulldown-Gene_names_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
YWHAZ	Pathway Commons Protein-Protein Interactions	1.0	null
Antisynthetase syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
OCUM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
secretory granule membrane	GO Cellular Component Annotations 2025	1.0	null
IPO7	Pathway Commons Protein-Protein Interactions	1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.10192
SU8686	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64579
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05919
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.963062
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HU-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24677
GSE148066,GSE157787_2_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36306
Ventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
PMC5993681-mmc4.xlsx-Tabelle1-Metacore_analysis_of_SRF_binding_targets_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL11	Pathway Commons Protein-Protein Interactions	1.0	null
RPL4	Pathway Commons Protein-Protein Interactions	1.0	null
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.09183
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058761
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.478
MHHCALL2	CCLE Cell Line Gene CNV Profiles	1.0	1.57276
MARK3	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.129
CDHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02044
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040167
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-1_UCSC_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.663
enzyme binding	GO Molecular Function Annotations 2015	1.0	null
GSU	DepMap CRISPR Gene Dependency	1.0	10.4617
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	2.19983
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900312
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77162
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81913
Serpin domain	InterPro Predicted Protein Domain Annotations	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	2.24305
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.361
captopril_mus musculus_gpl1261_gds3683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7367-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KRT1	Pathway Commons Protein-Protein Interactions	1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.41967
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831995
EEA1	Pathway Commons Protein-Protein Interactions	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25273
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF629	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4542
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8189
ABC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.68469
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68358
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00741
PRKAG2	Pathway Commons Protein-Protein Interactions	1.0	null
S117	CCLE Cell Line Gene Expression Profiles	1.0	1.35416
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73662
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
RI1	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
negative regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7074
NCIH2052	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.1363
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5373-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18114
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.940917
EIF3I	Pathway Commons Protein-Protein Interactions	1.0	null
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78919
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.25195
SF3B2	Pathway Commons Protein-Protein Interactions	1.0	null
HCC56	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3476
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12561
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12405
RPL5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190864,GSE190907_1_v_0_cacybp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TT	Achilles Cell Line Gene Essentiality Profiles	1.0	1.18095
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4352-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFSF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ndc80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.937
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00226
head bobbing	MGI Mouse Phenotype Associations 2023	1.0	null
RPN1	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of endopeptidase activity	GO Biological Process Annotations 2023	1.0	null
NQO2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12561
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC2	Pathway Commons Protein-Protein Interactions	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	2.64286
chr18_63519725_C_T_b38	GTEx eQTL 2025	1.0	1.19433
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33668
RPS16	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932363
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RRBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.95906
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.394863
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52063
STK33	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAT	Pathway Commons Protein-Protein Interactions	1.0	null
DDR1	Pathway Commons Protein-Protein Interactions	1.0	null
EDC4	Pathway Commons Protein-Protein Interactions	1.0	null
KRT15	Pathway Commons Protein-Protein Interactions	1.0	null
negative regulation of protein catabolic process	GO Biological Process Annotations 2025	1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23744
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19516
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22591
TNPO1	Pathway Commons Protein-Protein Interactions	1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06669
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29526
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12937
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLAT	Pathway Commons Protein-Protein Interactions	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13857
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92478
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42474
ALB	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22691
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39279
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Secretory granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2567
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
HPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7377
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24783
MKNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE143955_1_v_2_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUB1	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68542
regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25512
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.70632
Weight Gain	CTD Gene-Disease Associations	1.0	1.03271
ZNF750_KD_GSE38039_696_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3419-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34619
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	4.07349
GOLGA2	Pathway Commons Protein-Protein Interactions	1.0	null
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.77
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932363
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.83856
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPA3	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41525
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBA52	Pathway Commons Protein-Protein Interactions	1.0	null
COL8A1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907445
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6472-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16551
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
J82	DepMap CRISPR Gene Dependency	1.0	3.17868
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCNT1	Pathway Commons Protein-Protein Interactions	1.0	null
IDS	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.3342
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
EIF3A	Pathway Commons Protein-Protein Interactions	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.83959
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5817
Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12711
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A814-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15516
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8435
JJN3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.61345
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
hsf1_00000000_tcell_lof_mouse_gpl1261_gse41005	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.478737
EPRS	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30326
KRT19	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26601
NP8	DepMap CRISPR Gene Dependency	1.0	2.08745
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0469
mantle zone of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00534
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.22263
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38876
DIFI	DepMap CRISPR Gene Dependency	1.0	11.8419
Serine protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.136
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90259
MATR3	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_hexaplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22453
UTRN	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_ST-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.938839
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43065
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1701
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11715
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09065
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06485
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
NCI-H2085	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pioglitazone_mus musculus_gpl2897_gse8806	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85794
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.43494
RPL12	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235644_1_v_0_fasn_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051499
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9354
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.897334
PSMA7	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
LGALS3BP	Pathway Commons Protein-Protein Interactions	1.0	null
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64087
PKN2	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55349
TNK2	Pathway Commons Protein-Protein Interactions	1.0	null
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36083
ACOX1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
ficolin-1-rich granule	GO Cellular Component Annotations 2023	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19515
Adrenocortical carcinoma_ACC_TCGA-OR-A5JD-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66405
DST	Pathway Commons Protein-Protein Interactions	1.0	null
MRE11A	Pathway Commons Protein-Protein Interactions	1.0	null
RPL13	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
YKG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
AURKB	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5510_KO_Vdr/Med1_SRP282245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.8539
NAP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280439
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178340_5_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88882
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00435
EIF3F	Pathway Commons Protein-Protein Interactions	1.0	null
ATP5A1	Pathway Commons Protein-Protein Interactions	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.75438
SYK	Pathway Commons Protein-Protein Interactions	1.0	null
oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.987162
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KRT10	Pathway Commons Protein-Protein Interactions	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988284
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.86733
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2415
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13552
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14374
salivary gland	HPA Tissue Protein Expression Profiles	1.0	1.86733
SOX9_01_309	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.73039
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02549
HTK	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08931
Lung adenocarcinoma_LUAD_TCGA-50-6593-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTNNB1_Inactivation_GDS2984_628_mouse_Intestinal crypts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CAD	Pathway Commons Protein-Protein Interactions	1.0	null
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1479
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75122
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.74131
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.92111
extracellular region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157218
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76555
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85499
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46G-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fra-1_KO_GDS5078_402_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16551
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
Lhx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2349
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.91231
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.54287
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26973
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0344
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29785
CORL95	CCLE Cell Line Gene CNV Profiles	1.0	1.64699
ficolin-1-rich granule	GO Cellular Component Annotations 2025	1.0	null
METTL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93219
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02445
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL8	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21572
Cytolytic granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
Keratohyalin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15006
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
POSTN_01_293	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.03061
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.93075
HNRNPA1	Pathway Commons Protein-Protein Interactions	1.0	null
MINO	CCLE Cell Line Gene CNV Profiles	1.0	1.45777
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.922291
RPS3A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1926
stomach	HPA Tissue Protein Expression Profiles	1.0	1.01958
BALL-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.09431
KRT5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34416
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2796
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16551
PDS5A	Pathway Commons Protein-Protein Interactions	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6325
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10584
DYNC1I2	Pathway Commons Protein-Protein Interactions	1.0	null
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52212
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63368
extracellular space	GO Cellular Component Annotations 2015	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9186
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33132
regulation of protein catabolic process	GO Biological Process Annotations 2015	1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.82462
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990734
GSE226452_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GAK	Pathway Commons Protein-Protein Interactions	1.0	null
FUS	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A51Y-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BL6636 (FOXK2)	NURSA Protein Complexes	1.0	null
SNU213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60586
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16361
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07775
BL2030 (RFWD2)	NURSA Protein Complexes	1.0	null
PMC10539177-41375_2023_2003_MOESM2_ESM.xlsx-CCF-Gene_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC9464213-41467_2022_33063_MOESM9_ESM.xlsx-BNC2_peptides-gene_name_BNC2	Rummagene Transcription Factor Associations 2026	1.0	null
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26403
AURKA	Pathway Commons Protein-Protein Interactions	1.0	null
PIM1	Pathway Commons Protein-Protein Interactions	1.0	null
Caco-2/BBe cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNUC1	DepMap CRISPR Gene Dependency	1.0	3.11458
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LNZ308	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.26483
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831995
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30169
organelle	GO Cellular Component Annotations 2015	1.0	null
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02237
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41525
HSD17B4	Pathway Commons Protein-Protein Interactions	1.0	null
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05813
HOP-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.5991
FER	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22591
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68052
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
KRT18	Pathway Commons Protein-Protein Interactions	1.0	null
MNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72399
ZNF750_KD_GDS4599_177_human_HaCaT keratinocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.75881
TP53BP1	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC5	Pathway Commons Protein-Protein Interactions	1.0	null
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31933
RPL24	Pathway Commons Protein-Protein Interactions	1.0	null
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06307
RS411	CCLE Cell Line Gene Expression Profiles	1.0	2.53715
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1989
DSG1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61146
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22442
Immune System	Reactome Pathways 2024	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29755
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.5458
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.4892
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
NAT10	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03242
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02742
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826826
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857655
GRANTA519	CCLE Cell Line Gene CNV Profiles	1.0	2.365
NIP7	Pathway Commons Protein-Protein Interactions	1.0	null
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	2.10434
RAD50	Pathway Commons Protein-Protein Interactions	1.0	null
EPHA4_knockout_227_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.31881
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RPL18	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH69	CCLE Cell Line Gene CNV Profiles	1.0	1.71504
IKBKE	Pathway Commons Protein-Protein Interactions	1.0	null
negative regulation of protein catabolic process	GO Biological Process Annotations 2023	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
UPF1	Pathway Commons Protein-Protein Interactions	1.0	null
TTN	Pathway Commons Protein-Protein Interactions	1.0	null
t70-white-adipose_male_4w	MoTrPAC Rat Endurance Exercise Training	1.0	28.8038
HGC27	CCLE Cell Line Gene Expression Profiles	1.0	1.37537
RPS15A	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02567
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54875
TNIK	Pathway Commons Protein-Protein Interactions	1.0	null
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02394
RBMX	Pathway Commons Protein-Protein Interactions	1.0	null
DYNC1H1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18604_KO_Zfp708_SRP186171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.4208
External encapsulating structure	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BL4037 (CORO1A)	NURSA Protein Complexes	1.0	null
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Serpin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6602
AAK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.5458
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.04632
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NERF2-26677805-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17486_KO_Otub2_SRP314435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.72871
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28158
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
Ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20039
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.37965
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM83H	Pathway Commons Protein-Protein Interactions	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Midbrain, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05529
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8877
PRPF19	Pathway Commons Protein-Protein Interactions	1.0	null
LS1034	DepMap CRISPR Gene Dependency	1.0	5.83047
SIMA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00028
RPL7	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_16117_KO_Mfn1_SRP189355	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.57246
NUMA1	Pathway Commons Protein-Protein Interactions	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2934
TAL1	ChEA Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	1.5231
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07401
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3182
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
S100A9	Pathway Commons Protein-Protein Interactions	1.0	null
COPB1	Pathway Commons Protein-Protein Interactions	1.0	null
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.40216
LS123	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38698
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACOT8	Pathway Commons Protein-Protein Interactions	1.0	null
HS683	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.03968
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36251
PMC12749419-41598_2025_28826_MOESM3_ESM.xlsx-RFT_iBody3_triplicate-Genes_MBD1	Rummagene Transcription Factor Associations 2026	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2997
Glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02445
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44306
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14686
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832103
ACTN4	Pathway Commons Protein-Protein Interactions	1.0	null
BL2016 (AGAP3)	NURSA Protein Complexes	1.0	null
ficolin-1-rich granule membrane	GO Cellular Component Annotations 2025	1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.2293
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
SKIV2L2	Pathway Commons Protein-Protein Interactions	1.0	null
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8913
PMC11686977-12967_2024_5960_MOESM9_ESM.xlsx-Sheet1-Supplementary_Table_4_The_co-precipitated_proteins_of_the_four_RORA_promoter_probes_P1_P2_P3_and_P4_and_beads_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07881
GSE196780_1_v_0_puerarin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Serpin family	InterPro Predicted Protein Domain Annotations	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6595
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8816
LARP1	Pathway Commons Protein-Protein Interactions	1.0	null
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
KRT73	Pathway Commons Protein-Protein Interactions	1.0	null
CUL2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12721900-jci-136-187998-s161.xlsx-Flag-ETS1_vs_vector-Gene_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5685
SKCO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.81575
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
Rheaume et al.Nat Commun.21_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
head bobbing	IMPC Knockout Mouse Phenotypes	1.0	null
Peptidase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.113
HEC265	CCLE Cell Line Gene Expression Profiles	1.0	1.42793
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4072
CTCF	ENCODE Transcription Factor Targets	1.0	null
EIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
negative regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05935
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5931-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY7	CCLE Cell Line Gene CNV Profiles	1.0	1.40558
SW1116	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43586
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5814
TEX13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04603
RMG-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900312
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85879
GCN1L1	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44817
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36361
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07894
peptidase regulator activity	GO Molecular Function Annotations 2015	1.0	null
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13235
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7009
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
RPL7A	Pathway Commons Protein-Protein Interactions	1.0	null
MCF7	Achilles Cell Line Gene Essentiality Profiles	1.0	1.23207
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02072
Short bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30218
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	12.9526
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03839
ITGB4	Pathway Commons Protein-Protein Interactions	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SMARCA4	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_305_KD_Pabpn1_SRP318863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
paralemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03907
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	2.03286
regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
GSE223008_7_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CLRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.1014
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02949
PFKP	Pathway Commons Protein-Protein Interactions	1.0	null
PRPF8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226452_1_v_2_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AGRN	Pathway Commons Protein-Protein Interactions	1.0	null
KRT13	Pathway Commons Protein-Protein Interactions	1.0	null
enzyme inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
WTX_OE_GDS4802_34_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
negative regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
PRKAA2	Pathway Commons Protein-Protein Interactions	1.0	null
negative regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980587
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2011
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE218060_7_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.3942
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988284
SOX9_01_308	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.73039
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.706
SKMM2	CCLE Cell Line Gene CNV Profiles	1.0	2.59707
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
SKMM2	DepMap CRISPR Gene Dependency	1.0	5.26335
RPL10	Pathway Commons Protein-Protein Interactions	1.0	null
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
WTX_OE_GDS4802_325_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RPL18A	Pathway Commons Protein-Protein Interactions	1.0	null
PRKAB2	Pathway Commons Protein-Protein Interactions	1.0	null
RPS23	Pathway Commons Protein-Protein Interactions	1.0	null
TPR	Pathway Commons Protein-Protein Interactions	1.0	null
Neutrophil degranulation	Reactome Pathways 2024	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33451
Lid2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
CSNK2A1	Pathway Commons Protein-Protein Interactions	1.0	null
CPHXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63257
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1767
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02445
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9975
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TKKK	DepMap CRISPR Gene Dependency	1.0	2.8826
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08882
BL5495 (RAD18)	NURSA Protein Complexes	1.0	null
SIK3	Pathway Commons Protein-Protein Interactions	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12355
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
RANGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
SNRNP40	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE186647,GSE217288_11_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.43374
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	56.6593
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040199
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84194
STK4	Pathway Commons Protein-Protein Interactions	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.618
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29069
Fog2_KO_GDS3659_152_mouse_adult heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
peptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
Superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09892
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.08587
Lung squamous cell carcinoma_LUSC_TCGA-77-8140-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5776
RKO	Achilles Cell Line Gene Essentiality Profiles	1.0	1.41235
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33327
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64207
NMS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.711
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091613
GSE211286_7_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83122
extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03596
KIAA1524	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13961
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1619
EPPK1	Pathway Commons Protein-Protein Interactions	1.0	null
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0212
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.49137
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874262
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890692
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05956
negative regulation of protein catabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H1793	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL10A	Pathway Commons Protein-Protein Interactions	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.3947
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.66057
FLG2	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317545
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915507
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
GSE202434,GSE202438_12_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23581
Perturb_14232_Mut_Dpagt1_SRP230444	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831995
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52417
DPRX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3152
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08386
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
skin	GTEx Tissue Gene Expression Profiles	1.0	1.04848
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956718
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53452
LMO2	ChEA Transcription Factor Targets	1.0	null
Conjunctival epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
ANXA5	Pathway Commons Protein-Protein Interactions	1.0	null
Innate Immune System	Reactome Pathways 2024	1.0	null
GSE223008_0_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Gizzard	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Palisade parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.6
BL2264 (DOCK9)	NURSA Protein Complexes	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.751
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08764
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35365
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53109
CDK3	Pathway Commons Protein-Protein Interactions	1.0	null
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02394
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988284
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7706
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
RPL23	Pathway Commons Protein-Protein Interactions	1.0	null
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01791
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10843
KRT80	Pathway Commons Protein-Protein Interactions	1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70243
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20878
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2034
regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
RUVBL2	Pathway Commons Protein-Protein Interactions	1.0	null
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88783
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66846
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25177
LARS	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30992
DCD	Pathway Commons Protein-Protein Interactions	1.0	null
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93295
TAL1	ENCODE Transcription Factor Targets	1.0	null
Epidermal lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.961
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
negative regulation of catabolic process	GO Biological Process Annotations 2015	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.649
PARK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83236
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27451
OS252	DepMap CRISPR Gene Dependency	1.0	2.413
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_4_KO_Pabpn1l_SRP226170	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.33453
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81989
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.88028
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66405
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12856
PRPF4	Pathway Commons Protein-Protein Interactions	1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87032
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.49475
TMCO4	Pathway Commons Protein-Protein Interactions	1.0	null
Cul4B-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eosinophilia	DisGeNET Gene-Disease Associations	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07208
A1207	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22089
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43144
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7245
HNRNPUL2	Pathway Commons Protein-Protein Interactions	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051677
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.809
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93937
negative regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCARB1	Pathway Commons Protein-Protein Interactions	1.0	null
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
LYL1	ChEA Transcription Factor Targets	1.0	null
Exocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827572
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	1.0	2.4821
KMS20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48356
NCIH2085	CCLE Cell Line Gene Expression Profiles	1.0	1.44694
Epidermolytic palmoplantar keratoderma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42629
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	1.81186
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2844
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85879
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.232
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977271
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53692
EIF3C	Pathway Commons Protein-Protein Interactions	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9032
AIMP1	Pathway Commons Protein-Protein Interactions	1.0	null
BCAP31	Pathway Commons Protein-Protein Interactions	1.0	null
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12871
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
valproic acid_mus musculus_gpl6885_gse35291	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KRT14	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF3A1	Pathway Commons Protein-Protein Interactions	1.0	null
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3518
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6327
squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.770685
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GOS3	CCLE Cell Line Gene Expression Profiles	1.0	1.50039
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02002
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
BL5519 (PCNT)	NURSA Protein Complexes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.681034
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
magnocellular diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46177
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39951
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68268
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84194
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047253
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.15223
ALYREF	Pathway Commons Protein-Protein Interactions	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87216
A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.82761
TENT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32226
cellular_component	GO Cellular Component Annotations 2015	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9699
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2126	DepMap CRISPR Gene Dependency	1.0	2.28585
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46643
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH747	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65165
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30218
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7302
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33273
striatal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69725
BL5963 (RAF1)	NURSA Protein Complexes	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846478
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of peptidase activity	GO Biological Process Annotations 2023	1.0	null
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0531
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.438
MYC	ENCODE Transcription Factor Targets	1.0	null
short tibia	IMPC Knockout Mouse Phenotypes	1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93523
PTMS	Pathway Commons Protein-Protein Interactions	1.0	null
PRDX1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7309
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01213
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.987567
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02343
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.887989
PSMA2	Pathway Commons Protein-Protein Interactions	1.0	null
DSC1	Pathway Commons Protein-Protein Interactions	1.0	null
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HTATSF1	Pathway Commons Protein-Protein Interactions	1.0	null
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21897
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
FBXO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67931
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.09431
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935138
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.09
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03977
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12056
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.38957
Extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11883
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28116
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5809
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964816
AMER1_OE_GDS4802_549_human_HEK293	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
short tibia	MGI Mouse Phenotype Associations 2023	1.0	null
negative regulation of protein metabolic process	GO Biological Process Annotations 2025	1.0	null
Perturb_14972_KO_Max_SRP225905	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.9871
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57903
Infertility, Female	CTD Gene-Disease Associations	1.0	1.2415
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04324
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61616
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39125
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53023
PSMD3	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPDL	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11853_KO_Gdf2/Bmp10_ERP128742	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.22076
NSUN2	Pathway Commons Protein-Protein Interactions	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58368
DAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57298
UNKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38826
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937746
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89347
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60767
NCIH1693	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7748
ZNF317	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5879
RPS19	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NGDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13877
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.82273
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
vitamin e_mus musculus_gpl1261_gse42813	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPL13A	Pathway Commons Protein-Protein Interactions	1.0	null
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
tertiary granule	GO Cellular Component Annotations 2023	1.0	null
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.948
GSE148066,GSE157787_11_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KRT7	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7425-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMC2	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3HV-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.265
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67887
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
endopeptidase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70069
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8661
496100348_TCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57456
PSMA6	Pathway Commons Protein-Protein Interactions	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040588
BMP2K	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A65V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5059
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268828
intracellular part	GO Cellular Component Annotations 2015	1.0	null
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8579
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01552
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7542-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6643
HCT8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52858
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PROX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56769
pallidal part of olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45411
HECW2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
SNRPD3	Pathway Commons Protein-Protein Interactions	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
IQGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1989
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20039
hematopoietic progenitor cell differentiation	GO Biological Process Annotations 2015	1.0	null
DNAJC10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF3E	Pathway Commons Protein-Protein Interactions	1.0	null
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50481
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53007
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC1	Pathway Commons Protein-Protein Interactions	1.0	null
collagen-containing extracellular matrix	GO Cellular Component Annotations 2023	1.0	null
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
JUP	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07425
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8922
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1839
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.43417
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10174
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5388
HIST1H1A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.31635
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LN215	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55598
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
GEMIN5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
PDPK1	Pathway Commons Protein-Protein Interactions	1.0	null
RPN2	Pathway Commons Protein-Protein Interactions	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.492
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16089
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.83402
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909356
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01013
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04831
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471927
EZH2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE173232_1_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40161
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
CSE1L	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.07023
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75721
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47827
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053948
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.3598
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64171
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reticular formation of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1598
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07161
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03375
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6619
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13235
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10329
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16089
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71467
Kidney Chromophobe_KICH_TCGA-KN-8425-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165174,GSE165175_0_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9041
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14271
ALDH3A2	Pathway Commons Protein-Protein Interactions	1.0	null
GCT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55485
C1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1182
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17776
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852061
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31866
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SC-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.09431
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17368
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03774
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26871
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP7	Pathway Commons Protein-Protein Interactions	1.0	null
ROBO4	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58014
negative regulation of endopeptidase activity	GO Biological Process Annotations 2023	1.0	null
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.838914
OELE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2048
SIK2	Pathway Commons Protein-Protein Interactions	1.0	null
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCD	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10189495-mmc7.xlsx-TCF4_wk1-gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986397
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16094
AIMP2	Pathway Commons Protein-Protein Interactions	1.0	null
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29728
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40379
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23063
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
PSMD12	Pathway Commons Protein-Protein Interactions	1.0	null
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07181
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059577
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12984
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56158
polymorph layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82267
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14584
PMC5985538-mmc2.xlsx-selected_2X_in_2_exp_SALL1_FL-Gene_names_SALL1	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
COPA	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HS-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16361
bsc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.33813
HARA	DepMap CRISPR Gene Dependency	1.0	2.04495
RPS9	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834989
KMS11	CCLE Cell Line Gene Expression Profiles	1.0	1.5091
corticoid layer of TuPal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28356
MET	Pathway Commons Protein-Protein Interactions	1.0	null
MAPK14	Pathway Commons Protein-Protein Interactions	1.0	null
GSE120370_0_v_6_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9737
COPB2	Pathway Commons Protein-Protein Interactions	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27294
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.73223
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06417
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26827
negative regulation of catabolic process	GO Biological Process Annotations 2023	1.0	null
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87577
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93411
RANBP2	Pathway Commons Protein-Protein Interactions	1.0	null
PKN1	Pathway Commons Protein-Protein Interactions	1.0	null
496100530_FWM_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.61554
ULK3	Pathway Commons Protein-Protein Interactions	1.0	null
oviduct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703127
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory tubercle, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17236
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26178
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01952
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37061
RPS6KA6	Pathway Commons Protein-Protein Interactions	1.0	null
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04243
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51501
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KNS62	CCLE Cell Line Gene Expression Profiles	1.0	1.99677
PDHB	Pathway Commons Protein-Protein Interactions	1.0	null
ARG1	Pathway Commons Protein-Protein Interactions	1.0	null
regulation of protein catabolic process	GO Biological Process Annotations 2025	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29706
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41008
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07291
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2871
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.8692
TBK1	Pathway Commons Protein-Protein Interactions	1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.7144
MV411	DepMap CRISPR Gene Dependency	1.0	2.39427
RPL19	Pathway Commons Protein-Protein Interactions	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.48522
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
UBR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
EGFR_druginhibition_82_GSE27638	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.75963
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UACC893	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49372
Perturb_14661_KO_Insm1|Pax6_ERP127840	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.938131
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78919
r1 part of intermediate nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35506
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GPRC5A	Pathway Commons Protein-Protein Interactions	1.0	null
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07865
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
RB1_KD_GSE50532_624_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KRT9	Pathway Commons Protein-Protein Interactions	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6203
Photoreceptor proximal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LS513	Achilles Cell Line Gene Essentiality Profiles	1.0	2.40724
regulation of catabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35611
RPS12	Pathway Commons Protein-Protein Interactions	1.0	null
RPS14	Pathway Commons Protein-Protein Interactions	1.0	null
SOGA1	Pathway Commons Protein-Protein Interactions	1.0	null
FOSL1_KO_GSE43695_680_mouse_lung, PBS treatment	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RPS28	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22038
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11442
VPRBP_KD_GDS4829_90_human_DU145 prostate cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50018
EM2	DepMap CRISPR Gene Dependency	1.0	5.27449
ficolin-1-rich granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KRT6B	Pathway Commons Protein-Protein Interactions	1.0	null
UCHL5	Pathway Commons Protein-Protein Interactions	1.0	null
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
OCILY3	CCLE Cell Line Gene CNV Profiles	1.0	1.83902
XRN2	Pathway Commons Protein-Protein Interactions	1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	4.32495
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.08883
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.3
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
PMC10189495-mmc10.xlsx-TCF4_wk1-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EXOSC10	Pathway Commons Protein-Protein Interactions	1.0	null
RPS6KA3	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GANAB	Pathway Commons Protein-Protein Interactions	1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14172
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7966
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.10604
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.28501
APOB	Pathway Commons Protein-Protein Interactions	1.0	null
CORL23	DepMap CRISPR Gene Dependency	1.0	6.37824
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39949
FLI1	ChEA Transcription Factor Targets	1.0	null
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
PUF60	Pathway Commons Protein-Protein Interactions	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Tertiary granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
endopeptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
superficial stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69832
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08764
MAP3K11	Pathway Commons Protein-Protein Interactions	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61398
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBA1B	Pathway Commons Protein-Protein Interactions	1.0	null
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6702
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.41344
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH508	CCLE Cell Line Gene Expression Profiles	1.0	1.62132
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25997
KRT2	Pathway Commons Protein-Protein Interactions	1.0	null
CALCOCO2	Pathway Commons Protein-Protein Interactions	1.0	null
SF3B3	Pathway Commons Protein-Protein Interactions	1.0	null
KNS81	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.7651
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5034
FLT1	Pathway Commons Protein-Protein Interactions	1.0	null
H4C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27793
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039312
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.56473
TANK	Pathway Commons Protein-Protein Interactions	1.0	null
SK-MM-2	COSMIC Cell Line Gene CNV Profiles	1.0	2.09431
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5405
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42103
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.04375
HSC4	DepMap CRISPR Gene Dependency	1.0	2.38137
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	1.0	2.07531
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87032
Lung adenocarcinoma_LUAD_TCGA-80-5608-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20039
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2587
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMD2	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH889	CCLE Cell Line Gene CNV Profiles	1.0	1.95407
BTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80087
RPL15	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HNRNPL	Pathway Commons Protein-Protein Interactions	1.0	null
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32422
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8413
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42045
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55362
HEC151	CCLE Cell Line Gene Expression Profiles	1.0	1.88295
Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Visceral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
NCIH146	CCLE Cell Line Gene CNV Profiles	1.0	1.62557
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4523
spleen	HPA Tissue Protein Expression Profiles	-1.0	-2.10845
Acute Myeloid Leukemia_LAML_TCGA-AB-2835-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13529
KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Endocuticle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
intermediate stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16082
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18685
OUMS23	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39818
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.36679
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06285
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1025
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5553
PMC5998130-41467_2018_4619_MOESM7_ESM.xlsx-specificity_NCOA3-Gene_Name_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
LMNA	Pathway Commons Protein-Protein Interactions	1.0	null
XPO1	Pathway Commons Protein-Protein Interactions	1.0	null
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49915
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33517
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7892
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14168
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93753
LYSP100-associated nuclear domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
BL294 (RPRD2)	NURSA Protein Complexes	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062618
PMC8566473-41467_2021_26653_MOESM3_ESM.xlsx-SOX2_interacting_proteins-Gene_symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BQ-01C-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.809185
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50417
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33392
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51375
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.18392
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.003168
TMC4	Pathway Commons Protein-Protein Interactions	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15508
GPM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32434
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20744
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNUC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03359
EIF3L	Pathway Commons Protein-Protein Interactions	1.0	null
negative regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.95751
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
AP2A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STK10	Pathway Commons Protein-Protein Interactions	1.0	null
RPL14	Pathway Commons Protein-Protein Interactions	1.0	null
T3M4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.345
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	1.05312
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	1.0	null
Epidermal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79333
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67303
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54364
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45778
PANC1005	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08414
RPS6KA1	Pathway Commons Protein-Protein Interactions	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86232
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26871
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9201
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
EPLC272H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4054
BL5675 (ANKRD26)	NURSA Protein Complexes	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8602451-41467_2021_26807_MOESM10_ESM.xlsx-P53_SUMO1_SUMO2_Ub-ID-Gene_Name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25997
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3724
HS600T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33624
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01083
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908126
negative regulation of catabolic process	GO Biological Process Annotations 2025	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03218
Paraneoplastic pemphigus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
THOC2	Pathway Commons Protein-Protein Interactions	1.0	null
RDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
TP53BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82255
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2834
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57667
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.4151
NCIH1993	DepMap CRISPR Gene Dependency	1.0	3.96891
RPS26	Pathway Commons Protein-Protein Interactions	1.0	null
NOP2	Pathway Commons Protein-Protein Interactions	1.0	null
Interstitial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
PDCD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46465
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11493
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3411
KRT6A	Pathway Commons Protein-Protein Interactions	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60767
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.866997
negative regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
SUDHL5	CCLE Cell Line Gene Expression Profiles	1.0	1.50338
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPAB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4485_OE_Mir29a/Mir29b1_SRP220351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.7471
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4XL-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19521
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.54671
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JY-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPAFII	DepMap CRISPR Gene Dependency	1.0	3.67379
PMC10079688-41467_2023_37633_MOESM7_ESM.xlsx-IP_JUN_after_pona_treatment-Supplementary_Data_4_List_of_interactors_of_JUN_identified_by_label-free_quantitative_proteomics_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC1	Pathway Commons Protein-Protein Interactions	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99912
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2802
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223008_7_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.54405
RMND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51445
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39485
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04324
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1989
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
SURF4	Pathway Commons Protein-Protein Interactions	1.0	null
secretory granule membrane	GO Cellular Component Annotations 2023	1.0	null
GRANTA-519	COSMIC Cell Line Gene CNV Profiles	1.0	2.09431
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL5844 (ZFC3H1)	NURSA Protein Complexes	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.885619
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44936
RPS27	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55165
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10497
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8602451-41467_2021_26807_MOESM8_ESM.xlsx-SALL1_SUMO-ID-Gene_name_SALL1	Rummagene Transcription Factor Associations 2026	1.0	null
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31051
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	HPA Tissue Protein Expression Profiles	-1.0	-1.15218
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149264,GSE149267_2_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37546
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
HEBP1	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPUL1	Pathway Commons Protein-Protein Interactions	1.0	null
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77619
Perturb_14412_KO_Cnot6/Cnot6L_SRP285826	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.8522
PMC11003700-pbio.3002240.s011.xlsx-MYCN-IMR32_RawData-Unnamed_2_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72136
ovary	HPA Tissue Protein Expression Profiles	-1.0	-2.10845
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
negative regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.86733
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043484
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040035
ab_N_YW (RFWD3)	NURSA Protein Complexes	1.0	null
PSMD1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60933
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04172
COLO-824	COSMIC Cell Line Gene CNV Profiles	1.0	2.09431
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67318
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_ST-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5_OE_GDS4978_548_human_L428-PAX5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
collagen-containing extracellular matrix	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60798
molecular_function	GO Molecular Function Annotations 2015	1.0	null
MELK	Pathway Commons Protein-Protein Interactions	1.0	null
DARS	Pathway Commons Protein-Protein Interactions	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4153
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5115-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS5	Pathway Commons Protein-Protein Interactions	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.08904
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15257
OV7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.37255
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23532
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19836
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63797
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KTN1	Pathway Commons Protein-Protein Interactions	1.0	null
Skin stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0465
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98382
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-3.9988
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4889-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postsubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13389
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
HCC1359	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36496
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PRKAA1	Pathway Commons Protein-Protein Interactions	1.0	null
OSBPL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24545
GSE148647_4_v_2_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
SCC4	DepMap CRISPR Gene Dependency	1.0	4.46132
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
HARA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65903
BMI1	Pathway Commons Protein-Protein Interactions	1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.64112
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14372
MARK1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.45762
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01048
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
GCSAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43574
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NoRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
external cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14584
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.909613
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.32811
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25997
Simian Acquired Immune Deficiency Syndrome_T lymphocyte_GSE4785	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.1588
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3256
Perturb_5511_KO_Vdr/Med1_SRP282245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE223287,GSE223290_2_v_4_braf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RTN4IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88166
RPSA	Pathway Commons Protein-Protein Interactions	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32053
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null