association	dataset	threshold value	standardized value
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2383
MITF	ChEA Transcription Factor Targets	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33897
CALU6	CCLE Cell Line Gene CNV Profiles	1.0	2.48377
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40273
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43754
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11553
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27085
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2123
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34559
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58845
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989682
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08277
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18015
SNU840	DepMap CRISPR Gene Dependency	1.0	2.96769
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.996168
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.794
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17438
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.968618
RSBN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55372
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7474
INHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4668
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36686
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.962379
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.29429
TMED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77397
hsa-miR-3679-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07778
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02859
RPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11552
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX8	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857752
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6551
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0519
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900327
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.92535
ARHGAP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54712
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
NCIH1694	DepMap CRISPR Gene Dependency	1.0	2.65928
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79703
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47496
SUGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90691
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46488
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-geneid_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943795
efo21	HPA Cell Line Gene Expression Profiles	-1.0	-1.30156
SKHEP1	DepMap CRISPR Gene Dependency	1.0	2.26801
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23056
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966264
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.99906
GTEX-WFON-1226-SM-3TW8F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1646
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867073
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28839
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889144
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.921692
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4007
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12977
LAMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12232
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953887
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2446
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39175
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	3.80901
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29151
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
gallbladder	HPA Tissue Gene Expression Profiles	-1.0	-0.830496
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41715
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.5407
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872807
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35541
Perturb_5955_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.32471
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33734
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	2.79487
MSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82639
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913455
SNAPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48911
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24474
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.988788
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13736
colo320dm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827154
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992581
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27608
SP140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46128
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.834128
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.56373
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.36196
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934234
Lung squamous cell carcinoma_LUSC_TCGA-98-A53B-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45851
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924102
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6994-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57047
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17494
SLC9A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05319
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10269
Cerebral cavernous malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.58042
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5598
KLF5-20875108-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR3G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7035
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4945-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11184788-40164_2024_526_MOESM4_ESM.xls-MSC-EV_proteins-Unnamed_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37587
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1321
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4833-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26363
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7209
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.876603
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951843
Perturb_14625_KO_OGT_SRP146064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.45477
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7388-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OW-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.0777
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.6226
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.961326
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15871
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49639
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01931
RAB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43168
YTHDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69484
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.56916
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00546
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5793
Perturb_3939_KD_APC_SRP199093	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.26731
PRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65048
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16014
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48507
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28136
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829973
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73244
Perturb_5983_KD_YBX3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.49271
Perturb_7662_KD_CTCF_SRP072272	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.52188
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.16622
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S2-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51738
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79693
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44698
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956291
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999482
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01831
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.999482
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.53687
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08448
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78565
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14368
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834736
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979509
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3906
CENPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20034
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1539
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-1426-SM-3GIKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966852
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860649
Sarcoma_SARC_TCGA-DX-A3LY-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42876
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910659
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88816
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
GTF2H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7945
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.65147
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CW-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.025974
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.958559
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930818
Perturb_7637_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33152
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.99255
hsa-miR-4802-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33645
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45935
Perturb_13769_KO_Kansl3_SRP225948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.0043
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1934
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5389
PLCPRF5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.0739
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07215
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909037
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0126-SM-2TC68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12065
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19074
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.663
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63722
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02519
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07089
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.991801
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74024
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11049
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13375
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14594
Perturb_8215_KD_SUB1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.17842
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843003
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4161-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17141
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85502
G6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87404
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.929146
GTEX-U3ZN-0126-SM-4DXUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844257
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.906552
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983234
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64595
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70302
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	160.103
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9137
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84778
A3KAW	DepMap CRISPR Gene Dependency	1.0	5.71946
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.66617
RAB33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26069
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37031
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35854
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	223.207
CLDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23762
ANGEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95186
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43937
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40676
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5018
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89075
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839512
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47477
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2696
CELF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74731
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45249
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06014
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15871
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.68189
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90523
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0S7-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06304
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836056
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7939
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43035
GTEX-POYW-0826-SM-2XCEM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991992
colonrectum_f	HPA Tissue Sample Gene Expression Profiles	1.0	1.13018
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.97177
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27178
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39921
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59488
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61399
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62606
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875674
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMBOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4422
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836635
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARS CoV_7Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44294
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31069
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39784
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LRP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02262
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3482
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26004
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.40431
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22621
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53503
Liver hepatocellular carcinoma_LIHC_TCGA-UB-AA0V-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58072
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.041689
Perturb_6787_KD_KRAS_ERP122260	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.8315
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.81391
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2O	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7961
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06962
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38759
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.83633
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15855
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5148
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3737
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15871
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23032
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6326
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46723
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9053
FOXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80017
biological_process	GO Biological Process Annotations 2015	1.0	null
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00998
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51456
GTEX-OHPM-0426-SM-3TW8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885397
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0135
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77404
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3091
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WM-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.63874
Mitochondrial DNA levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
negative regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
CMK	CCLE Cell Line Gene CNV Profiles	1.0	1.38088
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAPC-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1023
KRBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24491
Perturb_2837_KD_CDK12_SRP073459	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.56132
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.80098
AKT1_knockout_214_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.65231
SENP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06297
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.854349
SSBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99245
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58171
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966808
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.837058
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.373
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13042
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86564
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.908289
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.889103
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01557
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825142
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87998
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55219
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965838
MARCHF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58135
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04986
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905744
MPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32755
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855268
Perturb_13837_KO_Mov10_SRP091426	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.70146
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0171
NOMO1	DepMap CRISPR Gene Dependency	1.0	3.49832
negative regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-XOT4-0826-SM-4B66Y	GTEx Tissue Sample Gene Expression Profiles	1.0	3.20496
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52771
rectum_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.233
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5904_KD_EBNA1BP2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.83473
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.332
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87073
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51169
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40429
Perturb_7266_OE_OspC1_SRP368098	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.97393
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.861751
WM1799	DepMap CRISPR Gene Dependency	1.0	4.7874
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14451
SMOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61324
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8018
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CL-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953586
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4818-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.19
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7059
Perturb_5735_KD_NAP1L3_SRP121475	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.8917
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7063-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2582
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13355
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28209
MAGED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39018
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.07405
Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89309
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
PFAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94744
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05001
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07431
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7338
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95228
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03963
negative regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
NADSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45418
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.6618
9+0 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.254
TE9	DepMap CRISPR Gene Dependency	1.0	2.06974
Perturb_5891_KD_C5orf41_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.32782
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.174
smallintestine_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.9513
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35801
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4239
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SHISAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68016
SERHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26744
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844797
Perturb_7736_KD_CNOT1_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.1186
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22994
Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4363
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Complement component 3 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85853
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.32968
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.03716
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90418
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828742
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54326
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08277
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20687
EM2	DepMap CRISPR Gene Dependency	1.0	4.96801
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904681
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72618
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.960094
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54522
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37232
Heart Failure	dbGAP Gene-Trait Associations	1.0	0.012895
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85938
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48078
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855268
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028176
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KA-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39801
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50203
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67071
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33825
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.949255
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.978676
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.72177
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.841946
Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43198
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.321
PMC7606598-NIHMS1624889-supplement-1624889_Supp_Tab1-10.xlsx-S8_MR-JTI-genename_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.861243
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.4829
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.08104
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67916
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28983
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.51897
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80225
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6284
Thymus-medullary thymic epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	3.42837
TMEM208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65989
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845906
GTEX-WRHU-1026-SM-4E3ID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92329
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993463
NDUFA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66123
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13768
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T2-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TENM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39512
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88755
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44798
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97623
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899911
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72484
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980577
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26165
Perturb_6786_Mut_KRAS_ERP122260	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.69041
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68221
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69717
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1439
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.72846
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0534
MEIS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78749
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4998
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01271
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.14013
fat_x1.V2	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.874371
Perturb_13220_KO_Atxn7l3_SRP269420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.98601
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07909
disease	GWASdb SNP-Disease Associations	1.0	0.023832
HSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38398
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962204
DDIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4676
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-RNOR-1226-SM-48FDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885894
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02202
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20558
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03292
CSNK1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52118
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48808
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.940056
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855268
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37198
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949909
Brain Lower Grade Glioma_LGG_TCGA-RY-A83X-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
USP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11173
Perturb_15022_KD_RelA_SRP078053	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.06099
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A0TN-01A-21R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3475
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.857
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51135
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04312
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45007
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.39424
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13457
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28747
heart_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.996632
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.0285
MAPKAPK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6722
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27739
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06115
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2019_KO_Parp1_SRP243891	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.35076
SF3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29941
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83281
Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_4488_KO_Rnu11_SRP309496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.8266
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869128
SW948	CCLE Cell Line Gene CNV Profiles	1.0	1.96748
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.827513
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873493
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10775
regulation of proteolysis	GO Biological Process Annotations 2015	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26965
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14308
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06455
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05608
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0579
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77188
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24171
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45529
hsa-miR-651	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58593
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21603
SSX2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97577
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02371
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924728
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.88383
Protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.834
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08776
CHST13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58889
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.881098
hsa-miR-4802-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Perturb_6764_KO|KD_SERPINE2_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.75893
Perturb_12774_KO_C5ar1_SRP097094	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44544
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79119
CALU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.33483
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4092
NCIH2170	DepMap CRISPR Gene Dependency	1.0	2.44628
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39817
GK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41018
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07141
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32835
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941638
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8185471-mmc6.xlsx-up-_and_downregulated_genes-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_shared_FO_and_FC_regions_respectively_Related_to_Figure_6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_13722_KD_RUVBL1_SRP126055	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83264
KLK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83768
Lung squamous cell carcinoma_LUSC_TCGA-58-8393-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50146
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
AARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50495
EZH2	ENCODE Transcription Factor Targets	1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04742
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89648
HNRNPA2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47804
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69881
SDF2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.87546
TFB2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79776
GTEX-V1D1-0626-SM-4JBHN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10261
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06219
heart muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.0864
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09395
HYLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30153
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
thp1	HPA Cell Line Gene Expression Profiles	1.0	1.18766
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4143-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-2526-SM-3MJGT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13665
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43159
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09392
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64177
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57904
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNPDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70032
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926319
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972991
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1969
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59421
Perturb_3594_KO_DELE1_SRP218218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.23317
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41099
SW403	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
FOXN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4589
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895676
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64517
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35001
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4974-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1358_KD_GANAB_SRP299805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.79176
GTEX-W5WG-1826-SM-4KL2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863018
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
Perturb_10219_KO_TNFAIP6_ERP126958	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.29246
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37044
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965194
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85747
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.7738
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
Vitelline envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.897
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966264
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31464
OCIAML3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34619
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39843
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-8121-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01639
Lung squamous cell carcinoma_LUSC_TCGA-43-A475-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Wop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IU-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	188.684
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A27C-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.899473
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
cellular_component	GO Cellular Component Annotations 2015	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.99329
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13411
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0673
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.71689
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.962379
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877926
CCC5	DepMap CRISPR Gene Dependency	1.0	4.67814
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23327
NCIH716	DepMap CRISPR Gene Dependency	1.0	3.18152
Perturb_3595_KO_HRI_SRP218218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.24929
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09134
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.19858
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.41691
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6078
MAD2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74112
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08934
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993735
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906757
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12518
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7H4-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2Q2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34171
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03922
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.22329
Perturb_13496_KD_IGF2BP1_SRP252425	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.64795
FN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82375
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84673
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930259
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.990936
Perturb_8819_KD_TRRAP_SRP106050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.7535
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.546
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15813
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07516
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3398
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891098
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.956
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4573
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10188
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18087
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912651
Epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27703
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.45
SKNEP1	DepMap CRISPR Gene Dependency	1.0	3.14165
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
DEPDC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38024
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865024
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CK-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42847
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35224
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81601
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2063
NAT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36425
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30177
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6516
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41027
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81631
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.8445
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893058
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877809
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2906_OE_MACROH2A2_SRP333362	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.14361
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22261
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47199
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16338
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8763
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14783
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.788288
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33361
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.76459
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26063
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10189
Perturb_6788_KD_NUDT21_ERP122260	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.302
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56157
GUCA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81151
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46117
Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6685
spleen_3c	HPA Tissue Sample Gene Expression Profiles	1.0	0.85254
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3055
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26819
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36924
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95902
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90258
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0532
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12946_KD_METTL3_SRP106608	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.91969
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95514
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.967691
extracellular space	GO Cellular Component Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-01A-21R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77897
enzyme inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944755
regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
TMEM106A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18725
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32962
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.5031
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76773
Perturb_15828_OE_Nrf2_SRP291726	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.67268
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49082
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TNFRSF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47733
GTEX-WHWD-0826-SM-3LK6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16884
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891861
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.59872
PMC9666480-Table_1.xlsx-P73-Unnamed_1_TP73	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52159
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.942828
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900548
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16644
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0283
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02748
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34492
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.824818
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05165
Outer acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
MMP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41682
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60701
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0769
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62509
MED6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42717
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45588
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16126
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7172
Perturb_3596_KO_DELE1_SRP218218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.41496
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35722
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	237.567
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10345
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.9534
HMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16468
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.81264
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4844-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4ND-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08161
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.726
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937951
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
COLO205	CCLE Cell Line Gene CNV Profiles	1.0	1.9705
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85555
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17395
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4368_KO_Peg10_SRP167954	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.533
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00015
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
MZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932842
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15972
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5346
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79935
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940578
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956291
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5787
GTEX-Q734-0226-SM-48U1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887604
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4838-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2710-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17504
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01511
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54685
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCK81	DepMap CRISPR Gene Dependency	1.0	4.72822
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23978
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38277
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37165
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3731
Perturb_13495_KD_IGF2BP1_SRP291710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.05932
Perturb_13776_KD_IFNAR2_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.95436
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.618018
GTEX-WWYW-1326-SM-3NB2S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20994
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16391
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0226-SM-3NMC8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863989
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7907
UACC812	CCLE Cell Line Gene CNV Profiles	1.0	2.41999
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939411
Perturb_15488_KD_SIM2_SRP218853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.88775
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48326
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19437
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916574
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04122
regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05858
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4881
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A463-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85645
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51218
BPH1	DepMap CRISPR Gene Dependency	1.0	2.3386
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBED-1726-SM-47JYO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3942
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.8401
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
C18orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79254
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89058
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32323
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903876
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5935_KD_MYBBP1A_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.0035
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00313
Eye-retinal pigment epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.09818
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24193
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54056
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7645-01A-22R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77131
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47229
HEP3B217	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03869
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
hsa-miR-1185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
NRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94459
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96705
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65334
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	3.12259
STX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18373
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79092
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835671
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68862
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46924
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3639
Perturb_4967_KD_LHX2_SRP324013	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.00304
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15225
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9547
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.908251
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71R-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.895918
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98277
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.413
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27182
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91647
Perturb_15827_OE_Nrf2_SRP291724	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.70441
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8589
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86416
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.02327
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10525
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923641
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934422
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90818
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3913
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55428
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9058
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84085
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61609
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XK-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06102
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RI-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.932076
ZNF707	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64174
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883306
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	2.13511
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38642
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ANKRD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45092
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02873
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.14042
RSL1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43208
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896296
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840101
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69478
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69716
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21692
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2442
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85998
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68761
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880626
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5804
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4569_KO_Prmt1_SRP178236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45933
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12246
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
GR	MotifMap Predicted Transcription Factor Targets	1.0	null
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05185
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62414
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.22994
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.34757
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.824818
ZNF667	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4408
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33332
Perturb_14319_KD_YAP_SRP251526	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.25605
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1671
outer CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51871
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852819
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31903
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09943
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of endopeptidase activity	GO Biological Process Annotations 2023	1.0	null
CTDNEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78223
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21616
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KML1	DepMap CRISPR Gene Dependency	1.0	2.15416
Perturb_7780_KD_NUDT21_SRP017305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.30866
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62681
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82837
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08169
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832799
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09527
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39871
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6554
PMC5474565-onc2016488x2.xlsx-Table_S4_MLL_Target_Genes-MV4-11_MLL-AF4_target_genes_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5913
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82827
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01184
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MO-1126-SM-4DM5D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997272
Brain Lower Grade Glioma_LGG_TCGA-HT-A5RB-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10448
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22601
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29329
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.34367
PDXP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2125
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49345
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07424
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844689
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.6459
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88016
FLI1	ChEA Transcription Factor Targets	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835051
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88589
SMAGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78798
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2405
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26853
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9005
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7398-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80398
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71414
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08695
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76759
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9648
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63992
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.934234
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49271
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48798
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61541
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71608
CERCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27348
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.24795
UBE2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63733
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840624
H3K36me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8845
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.38673
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993502
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
OCUM1	CCLE Cell Line Gene CNV Profiles	1.0	1.35567
SNU478	DepMap CRISPR Gene Dependency	1.0	2.51883
GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02173
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56461
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23126
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.05
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958797
Familial encephalopathy with neuroserpin inclusion bodies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-A5KK-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5504
IL17RE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69124
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22953
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12689
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77317
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32819
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8738
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10167
IRGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5634
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888809
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48366
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972147
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44125
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
NCIH1975	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39602
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51905
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09742
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08634
posterior cortical nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51533
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875755
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.392
TP53INP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4926
TBC1D17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44925
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28523
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833914
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4804-01A-02R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7133
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38923
all	GWASdb SNP-Phenotype Associations	1.0	0.028158
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28478
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A496-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TK-01A-42R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0126-SM-4BOO9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832238
CALU-6	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30158
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1054
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5529
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.34697
Perturb_5910_KD_GATAD2A_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.7421
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0277
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01291
appendices_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.35509
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2034
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3593_KO_HRI_SRP218218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.39993
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07212
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
TBC1D3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45928
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38244
REEP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26631
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.3298
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859792
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4341
Retinal pigment epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53978
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58126
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41458
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.927142
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94781
GTEX-OIZI-1426-SM-3NB1T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39875
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22282
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10883
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8153-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2026-SM-3GAF4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91383
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14287
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.926153
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864003
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BZ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Specific granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.043
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82275
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35565
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60058
IRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42324
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00942
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5342
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18577
Lung squamous cell carcinoma_LUSC_TCGA-68-A59J-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26401
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10827
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-970-SCMH1_SCMH1	Rummagene Transcription Factor Associations 2026	1.0	null
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09932
Perturb_1057_KO_Bcl9/Bcl9l_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43948
GTEX-VJWN-0726-SM-3GIJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965985
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.833789
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	1.0	2.96176
GTEX-XUJ4-1826-SM-4BOOU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987342
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22671
interleukin-20 receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.146
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897121
EIF4EBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82517
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.824563
Perturb_3531_OE_hsa_circ_0005358_SRP309967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.75917
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49519
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08485
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1994
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.60941
ZNF443	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67201
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.90501
GTEX-V1D1-2226-SM-3NMAX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07975
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.948891
TJP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95041
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.93655
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.346
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0978
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18783
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
NPY5R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31845
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04677
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97282
Sarcoma_SARC_TCGA-3B-A9HL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33949
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07205
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.0306
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.59542
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998248
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5249
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.956291
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29368
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
heart_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.926068
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32283
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23241
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2634
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04157
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.6406
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.90834
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07217
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8379
NAGLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12198
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.970559
SMSCTR	DepMap CRISPR Gene Dependency	1.0	2.87849
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19845
Perturb_1354_OE_U11_SRP314103	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0619
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.80714
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62064
NUP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65313
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70302
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17369
Perturb_6765_KD_PAF1_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.3049
FBXO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35318
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893871
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23538
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22349
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46995
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50274
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74975
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.918
negative regulation of endopeptidase activity	GO Biological Process Annotations 2023	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
negative regulation of peptidase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-TSE9-0426-SM-3DB81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17311
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11287
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15636
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
Arrector pili muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849783
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.071162
EVSAT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53324
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974384
SNU5	DepMap CRISPR Gene Dependency	1.0	3.31154
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95055
UTP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.012
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910806
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.834128
Lung adenocarcinoma_LUAD_TCGA-86-7954-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.49984
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944239
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883265
SW1463	CCLE Cell Line Gene CNV Profiles	1.0	1.65654
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999562
LLGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24053
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91419
Lung adenocarcinoma_LUAD_TCGA-55-6979-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988213
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84673
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.59057
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46104
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AW-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.836955
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5659_KO_SA2_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.1823
ZBTB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36565
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95875
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09952
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27787
negative regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37688
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.980099
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.98776
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.37669
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13286
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.04558
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.5088
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72924
CZIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46551
GAS2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79508
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2989
PIP5K1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19392
PCDHB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50949
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37986
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14021
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30766
WDR13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77845
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67455
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43261
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31711
Hair follicle epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4877
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89309
SCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5908
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40429
SUPV3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18818
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827997
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55008
GSE211983_0_v_2_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840858
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45866
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
BICR78	DepMap CRISPR Gene Dependency	1.0	2.25507
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3449
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46486
SCARF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11778
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35114
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4664
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50877
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07805
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00122
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20014
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58306
CTCF	ENCODE Transcription Factor Targets	1.0	null
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98726
Perturb_3265_KO_Tet2_ERP013684	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.4933
Hair follicle bulge stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23802
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15311
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39933
GSE128634,GSE128636_1_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HUNS1	DepMap CRISPR Gene Dependency	1.0	2.41919
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860329
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32175
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66622
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15019
RC3H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55941
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07483
RIMS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48933
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43858
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.233
EFM19	DepMap CRISPR Gene Dependency	1.0	14.0253
an3ca	HPA Cell Line Gene Expression Profiles	-1.0	-0.950601
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904681
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840016
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9163
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.8371
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17573
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17234
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23258
Perturb_3670_KO_FASTKD_SRP277516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.75247
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
L428	DepMap CRISPR Gene Dependency	1.0	2.34892
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5888
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17109
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70166
endopeptidase inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
serine-type endopeptidase inhibitor activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931215
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5729
IDI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52126
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
NCIH1573	CCLE Cell Line Gene CNV Profiles	1.0	2.12209
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.10084
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894825
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3116
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18539
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9408
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70613
NOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74269
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.235
Lung adenocarcinoma_LUAD_TCGA-05-5420-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMBC2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59459
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53084
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944194
FOSL2_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_928_OE_Scnn1b_SRP272853	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43684
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90899
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44767
MTMR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70878
Uterine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
ERG28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66298
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00627
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22665
Perturb_15737_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.59969
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.953762
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68302
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4768-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4409
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0776
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49044
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72617
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41751
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43187
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35788
LEMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79694
ODAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94135
RBM12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61759
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986245
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5957
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62718
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.884939
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.963
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50049
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05637
CLU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03248
PMC5789885-41467_2017_2812_MOESM4_ESM.xls-Supplementary_Data_1-Supplementary_Data_1_Non-cardiac_mesoderm_and_endoderm-permissive_differentiation_of_EOMES_KO_hESCs_EOMES	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972681
NCI-H508	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06582
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61387
LS513	CCLE Cell Line Gene CNV Profiles	1.0	1.54413
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10471
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-1.16817
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5922
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of protein processing	GO Biological Process Annotations 2015	1.0	null
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.73046
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12601
PPP5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29339
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47811
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58315
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859002
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
Perturb_623_KO_SLFN11_SRP233180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.50516
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0763
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7026
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0042
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65964
Kidney Chromophobe_KICH_TCGA-KN-8428-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VOPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23298
EW7	DepMap CRISPR Gene Dependency	1.0	3.20536
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12014
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23265
GTEX-XOTO-0011-R5A-SM-4B657	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985084
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08798
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03786
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46779
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19114
GDPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50737
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43526
SP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0959
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41047
Perturb_13782_KD_IFNAR2_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.40323
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23609
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6965
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4729-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91335
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SMARCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07451
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1614
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9538
Perturb_2345_KO_CGAS_ERP131756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36055
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06162
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1734	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65653
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990168
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10553
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8676
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.844831
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12676
ISLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78275
Optic disc area	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.704576
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
ASH3	DepMap CRISPR Gene Dependency	1.0	3.73656
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3157
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12169
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0264
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16764
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6452
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59199
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03019
WM88	DepMap CRISPR Gene Dependency	1.0	8.55638
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72539
Perturb_10233_KO_RN7SK_SRP201495	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.25826
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29133
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.1433
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUR-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66641
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58364
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50881
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83885
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0078
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.10824
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75741
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17135
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08841
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04454
SCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18949
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38678
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86605
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42518
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59308
MEC1	DepMap CRISPR Gene Dependency	1.0	3.2201
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.12422
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.981111
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942542
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17199
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4904_KO_NSUN6_SRP233222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42926
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.877963
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84131
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38034
EP300	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74957
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1315
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851272
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.76577
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.428
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8201
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.923643
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
NAA20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46851
CORL23	DepMap CRISPR Gene Dependency	1.0	2.63445
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21838
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.121
SLC35A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11495
FZD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01781
RABL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74282
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1421
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25081
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5439-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0315
KASUMI1	DepMap CRISPR Gene Dependency	1.0	3.01821
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12543
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55131
GTEX-T5JW-0326-SM-4DM6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0559
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01557
Photoreceptor connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.344
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7902
SPATS2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29273
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83102
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0995
Trophoblast stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.919592
ITGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9817
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86423
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.978676
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19954
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92368
EDEM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
RGMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27614
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
U937	CCLE Cell Line Gene CNV Profiles	1.0	1.39188
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00031
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R7-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30177
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	4.75185
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27739
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45224
HCC2157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88352
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909576
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5645
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35319
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02571
LARP4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74888
GTEX-OHPK-2426-SM-3MJGH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08037
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Optic nerve head parameters (multi-trait analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	5.01137
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11146
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903876
STRA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8907
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49526
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27019
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40255
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55832
CLK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98641
KPNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94249
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5146
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.04596
STOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49329
REST	ChEA Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09511
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41272
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02497
WDR90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54736
FAIM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12272
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7634_KD_DOT1L_SRP078067	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33152
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61292
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09846
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PJVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30899
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74451
RPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17592
Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MT-ND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80248
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73355
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22092
Sarcoma_SARC_TCGA-JV-A5VE-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
IRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41346
H4K20me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-0726-SM-447AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888605
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.184
ARPC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5423
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8337-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71003
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837779
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4233
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26893
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48323
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.847461
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38186
hela	HPA Cell Line Gene Expression Profiles	-1.0	-0.84055
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12485
PDCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27392
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MB-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893469
TWIST1_01_254	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.53332
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
colonrectum_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.02249
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03277
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
DDX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23791
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48085
GTEX-OIZH-1526-SM-3NB1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0047
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888971
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18259
MRPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71636
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.999969
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4664
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831861
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973718
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33414
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28478
TBC1D20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04308
UQCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09754
mRNA_DNMT3B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61223
SKUT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33246
Crx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6898
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6871
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.85148
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.88048
DRGX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37437
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
VPS37C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06043
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886038
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75851
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.57057
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34672
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GT-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1004
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14957
LAMTOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55773
CHD1_02_187	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.77761
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44579
Sarcoma_SARC_TCGA-K1-A6RU-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF318	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93801
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	1.56061
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825387
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69677
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5334-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82719
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6444
TR146	DepMap CRISPR Gene Dependency	1.0	2.50423
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962989
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26401
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73574
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30316
ASPRV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52734
PPARD	ChEA Transcription Factor Targets	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862698
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6458
GTEX-U3ZH-1726-SM-3DB79	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955794
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5275
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942472
Perturb_5916_KD_HNRNPK_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.5229
LN319	CCLE Cell Line Gene CNV Profiles	-1.0	-3.08158
ALDH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85785
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25874
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4258
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.3543
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12785_KO_C5ar1_SRP097094	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.66641
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39343
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924874
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59064
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89468
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33208
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12565
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LEFTY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49751
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2405
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tamoxifen_homo sapiens_gpl6480_gse12665	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21846
OUMS23	CCLE Cell Line Gene CNV Profiles	1.0	1.63684
Hair follicle bulge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
LPCAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6228
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15276
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973878
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.934353
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5004
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75011
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37417
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45719
Perturb_9008_KD_CDK12_SRP073459	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.0956
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964114
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63392
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05779
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KQ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIF1AN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85735
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.615
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12385
Peptidase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.819
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.40448
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3JL-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997573
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1889
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923666
OVSAHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53351
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51374
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97325
Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6145-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36477
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08721
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21505
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5834
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41587
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843573
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03059
endopeptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980799
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.3437
MCIDAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28201
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00684
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28036
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36547
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05131
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856579
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09233
Perturb_7661_KD_CTCF_SRP072272	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.76428
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986843
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1763
SLC16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09233
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89622
PMC10042887-41419_2023_5742_MOESM4_ESM.xlsx-Table_S4-Table_S4_Overlap_genes_of_HOXB3_vs_HOXB3-_and_APC-KO_vs_APC-intact_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896159
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.849277
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969547
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.986
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965878
Perturb_10705_OE_ATF5/PROX1/CYP3A4_SRP287297	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.32957
GTEX-QXCU-1926-SM-48FE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847684
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827663
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Exopher	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.814
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904746
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840178
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848466
Acute Myeloid Leukemia_LAML_TCGA-AB-2881-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7981
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44804
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52433
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65086
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4456
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04928
GSE97352_1_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18278
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.804576
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
GTEX-T6MO-1026-SM-4DM72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50864
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19926
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50865
Perturb_7244_KD_UPF1LL_SRP295982	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.36019
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8844
ATP5MF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26872
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50904
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.18215
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	1.87951
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF304	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74218
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.315
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.12928
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H6-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7223
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40646
Perturb_5963_KD_SETDB1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.18592
TMEM265	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64744
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.869171
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55764
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74555
peptidase inhibitor activity	GO Molecular Function Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33579
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2131
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06881
Perturb_5951_KD_RBM12B_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.47586
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIP4K2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6392
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32235
regulation of protein metabolic process	GO Biological Process Annotations 2015	1.0	null
MOLM13	DepMap CRISPR Gene Dependency	1.0	5.62567
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13893
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
inner CP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34021
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42147
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888237
DCAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02689
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9493
HESX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35092
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13673
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79943
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22302
CYP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01308
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04962
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08551
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89405
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	2.377
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955292
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11224
SGSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59247
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19859
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.47376
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08427
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01512
PDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30067
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905562
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.6381
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965441
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883523
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.50123
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17647
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07698
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61338
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.43319
GTEX-WXYG-0926-SM-3NB2O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938502
hl60	HPA Cell Line Gene Expression Profiles	1.0	2.18877
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89309
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16187
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54869
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44585
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990578
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7025
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30343
molecular_function	GO Molecular Function Annotations 2015	1.0	null
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89707
CEBPB	ENCODE Transcription Factor Targets	1.0	null
RH30	DepMap CRISPR Gene Dependency	1.0	2.05035
TIMM17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88712
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889266
GTEX-OHPK-0226-SM-3MJH6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27962
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0588
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84608
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96188
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07387
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919852
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.873412
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48211
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.991801
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67474
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2647
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909143
HMGCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81585
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58165
PEA1	DepMap CRISPR Gene Dependency	1.0	3.36104
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28762
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34107
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_30_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PAQR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03542
GTEX-R55C-1026-SM-48FCM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850339
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67012
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16326
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00133
NCIH522	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67609
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.91924
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47684
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
heart disease	GWASdb SNP-Disease Associations	1.0	0.173857
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93654
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863303
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21603
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22102
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826104
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13355
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93463
hsa-miR-548ai	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10907
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04409
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2335
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.90834
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10057
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70302
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22497
GTEX-T2IS-2026-SM-4DM6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02142
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
small intestine	HPA Tissue Gene Expression Profiles	1.0	0.982992
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16285
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47X-01A-31R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.13891
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24612
PYGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16814
Brain Lower Grade Glioma_LGG_TCGA-WY-A85D-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X1-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5937_KD_NCOA5_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.0155
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.37707
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RH-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45045
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3575
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83162
Perturb_5966_KD_SUMO2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.65792
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53027
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51828
endopeptidase regulator activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.66491
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HJ-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RUSQ-0226-SM-47JWT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46055
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
Rectum adenocarcinoma_READ_TCGA-EI-6512-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42887
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0774
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06568
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9372
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18109
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8472
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51022
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09036
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
JAR	DepMap CRISPR Gene Dependency	1.0	5.21556
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980731
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	151.377
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.61338
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9923
GNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45782
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BPNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27341
Perturb_4933_OE_KLF17_ERP131758	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.85348
negative regulation of peptidase activity	GO Biological Process Annotations 2023	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PYCARD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73455
ZKSCAN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60027
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.918899
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973632
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85981
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.201
WHSC1	ENCODE Transcription Factor Targets	1.0	null
Nrd1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74465
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825114
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5995_KD_ZNF638_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.77142
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25126
SCAMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01865
HDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42479
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21242
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6858
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64549
HCA1	DepMap CRISPR Gene Dependency	1.0	2.89364
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913143
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SK-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93165
GSE248858_5_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98824
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17076
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849038
negative regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08876
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891794
Perturb_3713_KO_PIWIL1_SRP188921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.21788
GTEX-R55G-1126-SM-48FDG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917102
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56237
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54043
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4923-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NT5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22313
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843036
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978152
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41338
FOS	ENCODE Transcription Factor Targets	1.0	null
TOR1AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5442-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947353
Prostate adenocarcinoma_PRAD_TCGA-CH-5788-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26461
Perturb_5921_KD_KHDRBS1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.44159
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0904
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94159
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23417
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19954
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.08107
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02703
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39917
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33422
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3OO-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K36me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32669
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34505
KBTBD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60327
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4438
GSE230263,GSE230265_3_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
PPIP5K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50307
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97019
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84645
BROX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66456
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7207
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1786
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.981654
ZNF77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92851
lymph node	HPA Tissue Gene Expression Profiles	1.0	0.863958
GTEX-P4PQ-1526-SM-3NMCK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34463
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
A-Netherlands-602-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.80434
Pancreas	GTEx Tissue Gene Expression Profiles 2023	1.0	2.27658
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93595
Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23284
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28648
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988348
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13018
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64335
TMEM35B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7393
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.2991
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	2.07927
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.29675
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39924
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6937
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1632
CMK115	CCLE Cell Line Gene CNV Profiles	1.0	1.54428
REST	ENCODE Transcription Factor Targets	1.0	null
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42421
hsa-miR-548ag	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HDMYZ	DepMap CRISPR Gene Dependency	1.0	4.72099
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03702
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27672
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49331
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919796
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30786
GABRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48147
ITM2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73008
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH841	DepMap CRISPR Gene Dependency	1.0	2.42303
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46199
Serpin domain	InterPro Predicted Protein Domain Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.88402
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82477
MEIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8738
RBBP5	ENCODE Transcription Factor Targets	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3305
Perturb_3563_KD_HMGA1_SRP299065	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.6269
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94081
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79533
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46241
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37986
Perturb_8681_KD_ZNF827_SRP318474	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38284
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CT-01A-31R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7469
Acrosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.598
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67985
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1409
Perturb_14261_KD_LINC00941_SRP156276	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.57037
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MM-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45078
SOX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06114
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4736-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118794_5_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81614
NCIH1373	DepMap CRISPR Gene Dependency	1.0	2.94895
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06773
Serpin family	InterPro Predicted Protein Domain Annotations	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969026
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924121
AS3MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7139
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68605
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
WNT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00829
congestive heart failure	GWASdb SNP-Disease Associations	1.0	0.55355
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
LUC7L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92546
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0826
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880349
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endopeptidase inhibitor activity	GO Molecular Function Annotations 2025	1.0	null
ANKRD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09733
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23056
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4411
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
PPP2R1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14774
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.694
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.828935
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31147
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25444
GTEX-WYBS-0426-SM-3NM9M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923821
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05968
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3584
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21175
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4934_OE_KLF17_ERP131959	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27288
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08194
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SM-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67495
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2047
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46293
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33414
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.458
Perturb_5907_KD_EXOSC10_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.7515
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.2103
Kidney Chromophobe_KICH_TCGA-KN-8431-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18883
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24612
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2399
GTEX-TMMY-1726-SM-4DXTD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836044
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.12684
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52397
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868193
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848955
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49107
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980041
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84451
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
RNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99741
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1634
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75944
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-0004-SM-3NMAC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36663
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75641
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71193
FBLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41887
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71374
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9615
ES4	DepMap CRISPR Gene Dependency	1.0	2.90732
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53599
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0003
Perturb_3849_KD_TGM2_SRP194250	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.18242
Perturb_4905_KO_NSUN6_SRP233222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.74703
W chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
Perturb_1095_KO_ATXN1L_SRP230198	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.26321
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
negative regulation of cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79483
SOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0301
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0581
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49728
rectum	HPA Tissue Protein Expression Profiles	1.0	1.57181
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TU-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888909
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9341
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7144
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43115
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.049727
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.832755
Prostate adenocarcinoma_PRAD_TCGA-EJ-8474-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY7	DepMap CRISPR Gene Dependency	1.0	2.79963
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00897
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1265
Perturb_3669_KO_FASTKD_SRP277516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.4236
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0406
Perturb_3958_KO_GSDMB_SRP350967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55457
NAALADL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47151
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13253
Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840858
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09036
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840858
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31988
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21036
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902774
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0833
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842839
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44249
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04074
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86746
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5081-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874451
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7464
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5848
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7145
C14orf119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46615
Sarcoma_SARC_TCGA-3B-A9HI-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36911
PARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10388
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00343
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2808
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850554
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27739
TRAPPC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43829
negative regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945287
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7504
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11707
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.07454
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864558
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
regulation of endopeptidase activity	GO Biological Process Annotations 2015	1.0	null
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.894825
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833175
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06854
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0133
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39588
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42681
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4609
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32203
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4873-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.6535
Serine protease inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.812
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.617
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09644
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09141
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84655
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847011
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.884038
DESI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40563
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17877
TMEM131L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65995
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2778
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45686
Perturb_5925_KD_LOXL1_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.3234
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07786
H3K27me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
a549	HPA Cell Line Gene Expression Profiles	-1.0	-1.38584
ZFP36L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55757
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05004
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
peptidase regulator activity	GO Molecular Function Annotations 2015	1.0	null
NUP155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7521
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1973
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.83106
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51848
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.950984
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00482
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALCOCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39741
Serpin, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.573874
PMC6855629-pone.0225186.s005.xlsx-Sheet1-DEGs_downregulated_in_the_low_MEIS1_content_thalamus_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_563_KD_MYCN_SRP158473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.13464
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54112
heart failure	GAD Gene-Disease Associations	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84661
E2F4	ENCODE Transcription Factor Targets	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.34399
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.87051
Perturb_4568_KO_Prmt1_SRP178236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06731
congestive heart failure	GWASdb SNP-Phenotype Associations	1.0	0.472104
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5403
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30059
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69933
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71052
biological regulation	GO Biological Process Annotations 2015	1.0	null
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18678
CRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04291
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7630-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null