association	dataset	threshold value	standardized value
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911329
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4925
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.451606
NEIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16101
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07369
A4GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55816
Gastrointestinal system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3901
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27124
GTEX-U8T8-2226-SM-3DB95	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09128
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22705
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40163
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E6-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18961
GTEX-R55C-0526-SM-3GIKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24756
C11orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82446
lung	GeneRIF Biological Term Annotations	1.0	null
PRSS53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94571
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.42166
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23357
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9946
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.08157
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7971
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76349
20035825-TableS7a	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYJK-0826-SM-3NM8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41523
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52387
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF623	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52461
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960499
Asthma (time to event)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5502
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus	HPA Tissue Gene Expression Profiles	1.0	0.915493
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-2.77685
Human - Lung v2 (HLCA) - L3 - AT2	HuBMAP Azimuth Cell Type Annotations	1.0	null
tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.202474
GSE226584,GSE226589_2_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PDE6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85547
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
CAKI2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80806
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
ARMC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18335
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4076
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0622
ATP6V1C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82507
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.8624
Lamina epithelialis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94883
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3143
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6991
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.80564
QGP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.79316
COL6A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1408
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63103
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40088
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94864
Corneal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
TRMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94743
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92845
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4707-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.22
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9433
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888031
RPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43754
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	10.1609
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42077
ZMAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
SNU761	DepMap CRISPR Gene Dependency	1.0	2.2379
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64087
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36967
CALU3	CCLE Cell Line Gene Expression Profiles	1.0	1.56942
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54717
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.52942
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
COX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4699
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14376
Adrenocortical carcinoma_ACC_TCGA-OR-A5JI-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
ROGDI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28944
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41188
RPMI8226	DepMap CRISPR Gene Dependency	1.0	2.67667
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7092
Rectum adenocarcinoma_READ_TCGA-AG-4022-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4213
GTEX-QV44-0926-SM-2S1RH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18691
TASOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39704
GTEX-U3ZN-1726-SM-4DXUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839271
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60286
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57144
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3881
B3GNT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56531
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38376
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61357
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3642
ZNF391	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29373
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08336
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13119
Lung adenocarcinoma_LUAD_TCGA-49-4486-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PABPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91396
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6982
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17471
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
GTEX-RVPV-0526-SM-47JYL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867167
NME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54041
Autoimmune disease of endocrine system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.549
NCIH1435	CCLE Cell Line Gene Expression Profiles	1.0	1.93891
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.256989
Nephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61791
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35484
CTHRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50821
GTEX-WYBS-1126-SM-3NMAM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956899
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36064
Acquired Immunodeficiency Syndrome	DisGeNET Gene-Phenotype Associations	1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
TLR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18674
OXLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28609
CDKN1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73634
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9192
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
periodontium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.557661
OPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53061
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5556
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21506
Adrenocortical carcinoma_ACC_TCGA-OR-A5LN-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6409
NIFK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12525
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.892
GTEX-W5WG-1626-SM-4LMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04088
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2313287	CCLE Cell Line Gene Expression Profiles	1.0	1.47409
ATN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37464
GTEX-PLZ4-1626-SM-3P618	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939285
Ameloblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
IM95	CCLE Cell Line Gene Expression Profiles	1.0	2.04811
NCIH810	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73216
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07005
Lung adenocarcinoma_LUAD_TCGA-97-8171-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927976
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84878
Kniest dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0636
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75534
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01063
PCI30	DepMap CRISPR Gene Dependency	1.0	2.37084
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41254
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6972
PANC1005	CCLE Cell Line Gene Expression Profiles	1.0	1.43052
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824907
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4054
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32341
Perturb_14557_OE_ZEB1_SRP051606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.63776
GTEX-WYVS-0526-SM-3NM9W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31455
DRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22621
FOXP1	ChEA Transcription Factor Targets	1.0	null
PEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64743
ZMAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05073
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7547
GSE80098,GSE80366_0_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
behcet's disease	GWASdb SNP-Disease Associations	1.0	0.992818
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880556
Achondrogenesis type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29435
KAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04612
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.514
tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390044
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EO-0926-SM-3P5Z2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978239
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.372369
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
TXNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57442
GTEX-SUCS-0626-SM-32PM5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48113
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7889-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24307
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14946
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WI-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
HMCB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.60116
PMC9396374-Table_4.XLSX-AR_related_genes_from_GeneCards-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5366
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89306
GTEX-WFG7-0526-SM-3GIKI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38316
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7671-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.106903
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7536
GSE193258,GSE193259_5_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-1226-SM-4DM5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839399
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43245
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199034_1_v_2_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35536
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52265
WSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0199
UBE2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6385
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33224
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WSCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81391
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
HELLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6043
hepatic granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.873556
SPATA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99387
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pharynx cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2597
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
ZNF251	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
GTEX-XBED-0826-SM-47JYC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56605
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47215
SOX2	ChEA Transcription Factor Targets	1.0	null
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225267
GTEX-U3ZM-0526-SM-4DXTB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844959
LHX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8845
GTEX-PWCY-1726-SM-48TD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03093
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53459
ZNF573	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02291
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BNIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2349
CST6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85033
496100606_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	12.1915
GSE131161_3_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61221
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44616
peptide	GeneRIF Biological Term Annotations	1.0	null
GATA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18698
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11647
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
ZNF787	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24547
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11898
HEPG2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49146
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68041
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.17784
Lung adenocarcinoma_LUAD_TCGA-62-8397-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46S-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PP-0526-SM-2HMKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50423
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914024
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32543
HCC78	CCLE Cell Line Gene Expression Profiles	1.0	1.61175
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0817
HCC95	DepMap CRISPR Gene Dependency	1.0	2.13243
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.201587
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
vagina	GTEx Tissue Gene Expression Profiles	1.0	1.0325
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26298
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49963
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40322
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5799
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.180001
PMEPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04296
WWC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78146
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.892806
all	GWASdb SNP-Phenotype Associations	1.0	0.048999
DEPDC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
Multiple epiphyseal dysplasia with myopia and deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03271
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66246
Lung adenocarcinoma_LUAD_TCGA-78-7633-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1215
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2518
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43777
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	8.03368
GTEX-RM2N-0426-SM-2TF4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36008
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67083
NCIH441	DepMap CRISPR Gene Dependency	1.0	2.378
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
OVMANA	DepMap CRISPR Gene Dependency	1.0	2.52658
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.89758
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98393
PMC4858740-ncomms11473-s2.xls-HAdV-D9_cr1b_Library_1-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
at1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
NCI-H441 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19379
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung-plasma cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.090384
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
NUTM2G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81634
Bladder-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0938997
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
B3GALNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25098
Lung adenocarcinoma_LUAD_TCGA-71-6725-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36761
CACFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76156
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62805
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12511
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95847
GADD45G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57051
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80786
GTEX-PWCY-0726-SM-48TCS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15449
GTEX-OXRP-0526-SM-2I3EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944561
GTEX-POMQ-0526-SM-3GADD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33197
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911912
GTEX-WOFM-0126-SM-3MJFE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49559
GLS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15585
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7043
Lung squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
TSSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21554
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0536
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60967
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96707
TFAP2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.258
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11493
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975766
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53579
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.989
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
GSE196671_5_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47355
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
chronic hepatitis	GWASdb SNP-Phenotype Associations	1.0	1.19766
FBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62591
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.975766
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.41149
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46944
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Systemic lupus erythematosus	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.358766
RAI14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88474
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JVE127	DepMap CRISPR Gene Dependency	1.0	2.04362
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32345
Connecting tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2647
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868045
GTEX-T8EM-0326-SM-3DB7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36732
RPL29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87158
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
THAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52218
BLOC1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68749
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939323
GTEX-SNOS-0426-SM-32PMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47481
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
Influenza	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
ZNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90763
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
CGAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64727
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
NINJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87562
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
Uterine disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46492
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13842
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
GTEX-QEG5-1126-SM-33HC2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41106
SLC15A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54836
different	GeneRIF Biological Term Annotations	1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7527
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38828
CACYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00997
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12147
GTEX-REY6-1326-SM-48FDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08277
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
RBM23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23082
PPP2R5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42291
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22554
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
GTEX-S3XE-0926-SM-4AD4S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03082
STX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44238
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33275
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.33822
abnormality of macrophages	GWASdb SNP-Phenotype Associations	1.0	0.326176
tissues	GeneRIF Biological Term Annotations	1.0	null
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9006
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6035
BOLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19253
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57659
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95653
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888534
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84086
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18383
ZCCHC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00722
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02624
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046575
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-1026-SM-4BOPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850408
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4158
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40326
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042217
MYCN	ChEA Transcription Factor Targets	1.0	null
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3151
XPNPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81745
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5633
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054893
Liver-liver dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0938997
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PECAPJ34CLONEC12	DepMap CRISPR Gene Dependency	1.0	2.82421
GTEX-S7SF-0926-SM-4AD4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12271
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81174
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
ZNF442	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17778
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABHD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90799
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971768
GTEX-T5JW-0726-SM-4DM6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862141
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55817
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18854
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070497
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1688
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869559
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054426
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80217
PGM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84443
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895137
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
GTEX-X62O-2226-SM-46MW3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967725
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4760-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3464
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0226-SM-4AT6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41594
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
GSE199606_6_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45344
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
Lung adenocarcinoma_LUAD_TCGA-78-7148-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
surfactant	GeneRIF Biological Term Annotations	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09777
GSE199606_6_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tongue-capillary endothelial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0938997
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03396
jf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
HOXC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3117
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27452
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08999
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35451
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842725
GSE193258,GSE193259_9_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATP6V0E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02748
ZNF225	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39023
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
GSE253579_1_v_0_sectm1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-PXR-Unnamed_0_NR1I2	Rummagene Transcription Factor Associations 2026	1.0	null
ATRAID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28415
TUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89323
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01661
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6664
disease by infectious agent	GWASdb SNP-Disease Associations	1.0	0.317169
HCC827	CCLE Cell Line Gene Expression Profiles	1.0	1.67605
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
496100288_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.15912
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36165
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Lung-serous cell of epithelium of bronchus	Tabula Sapiens Gene-Cell Associations	1.0	-0.0937785
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866322
GTEX-QCQG-0526-SM-48U2A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837249
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7428-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3118
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
Large Cell Neuroendocrine Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
NP3	DepMap CRISPR Gene Dependency	1.0	2.37984
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	7.05915
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.225252
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
EFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72004
Alveolar cell type II	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.335
TSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8556
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.79843
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46105
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
PMC8582123-13073_2021_996_MOESM3_ESM.xlsx-PITX1-HIT_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
SW1990	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
CL40	CCLE Cell Line Gene Expression Profiles	1.0	1.45197
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PLZ4-0726-SM-2TC6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965321
HCC1143	CCLE Cell Line Gene Expression Profiles	-1.0	-1.8434
ERICH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13721
BAT3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.235
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3305
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05366
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05155
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39623
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825198
H2AC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77508
kidney	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ6-0526-SM-3P61C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01028
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alveolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
PERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23623
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11155
ILVBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04153
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42513
Malignant tumor of pancreas_saliva_GSE14245	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.28927
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3116
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
CSNK1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50465
MBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59395
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1023
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.6152
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35663
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.79148
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30294
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
RMGI	CCLE Cell Line Gene Expression Profiles	1.0	1.40534
Kidney Chromophobe_KICH_TCGA-KL-8325-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
3D4/21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
possesses	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPM-0526-SM-2YUMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50667
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07068
CAPN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25308
GTEX-WFG8-1326-SM-4LVN3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841458
BMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44319
CMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25642
GTEX-VUSG-0926-SM-3GIK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21168
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19103
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35061
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7145
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12465
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77O-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2318
HS822T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75255
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
MTCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91853
HPAFII	CCLE Cell Line Gene Expression Profiles	1.0	1.64127
GTEX-X4XY-1026-SM-46MVX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08733
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PSDG-1126-SM-2S1ON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17043
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2237
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25T-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35675
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5163
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
NCIH2347	CCLE Cell Line Gene Expression Profiles	1.0	1.82056
STOML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92138
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRK-0926-SM-2HMKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45047
CREBZF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65516
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Clara cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6559
HDAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
Rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
DNASE1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70781
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09145
PHKA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48959
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50453
GTEX-S33H-0626-SM-2XCBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931627
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
GTEX-RN64-1026-SM-48FDX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88918
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
HCC1143	DepMap CRISPR Gene Dependency	1.0	2.01092
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.377
ECI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27595
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0294
HHUA	DepMap CRISPR Gene Dependency	1.0	2.33713
hsa-miR-4452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4127
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051645
GTEX-WWYW-0926-SM-3NB2Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10763
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TML8-1126-SM-4DXSS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865736
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20918
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lupus erythematosus, systemic	GAD Gene-Disease Associations	1.0	null
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32895
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
MIR221_KD_GDS4054_455_human_MCF7 breast cancer cells (fulvestrant-resistant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69173
KMRC20	DepMap CRISPR Gene Dependency	1.0	2.05327
MTLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.509
PMC12635344-41467_2025_64990_MOESM1_ESM.pdf-21-POU2AF1_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
TINF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09194
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57806
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49817
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03989
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74921
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19544
alveolar sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60893
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17929
ZNF865	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99835
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37123
GTEX-WRHU-0226-SM-3MJFV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29306
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
RHOQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70372
Glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21051
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7429
HS688AT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63296
AEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49807
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71949
GTEX-OOBK-0625-SM-3LK5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944183
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20351
Respiratory system_CT1_alveolar type I cell	HuBMAP ASCT+B Annotations	1.0	null
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37957
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9255
HES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7924
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38881
AKIRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46594
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Allergic rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
TSC22D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70989
GTEX-TKQ1-0326-SM-4DXSM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00026
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7193
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
HOXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5436
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.27139
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13572
ZNF700	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12127
TALDO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86495
Membranous Glomerulonephritis	DisGeNET Gene-Disease Associations	1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3019
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27787
DCXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48923
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06791
TRIM28	ChEA Transcription Factor Targets	1.0	null
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-R55G-1026-SM-48FDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03376
GTEX-WH7G-0926-SM-4LVMJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918608
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.538104
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.56371
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.9642
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.201587
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RHBDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52346
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042187
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11249
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21051
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13471
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67639
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71467
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34335
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25133
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986234
GTEX-XUW1-0326-SM-4BOOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858321
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7887-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-0826-SM-4AD5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900628
Ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4739-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2075
GTEX-PLZ5-0726-SM-2I5F9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3977
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38084
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.02815
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3081
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12118
POU6F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18139
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15483
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
GTEX-T6MO-1226-SM-4DM5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07393
NDUFA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89741
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9087
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0779
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970713
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37253
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
LAMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25895
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	2.55746
GTEX-S95S-0426-SM-4B64I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1627
311 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30294
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40965
FEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47126
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13968
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33131
Lung-fibroblast	Tabula Sapiens Gene-Cell Associations	1.0	-0.0938997
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
characterized	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34559
inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.31925
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27456
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
PC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1925
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17515
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
GTEX-QVUS-0626-SM-447CC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96054
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68515
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983871
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC1897	CCLE Cell Line Gene Expression Profiles	1.0	1.50102
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
XYLT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18985
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0513
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
UQCRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9447
Hypochondrogenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
BCDIN3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19887
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05266
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03587
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3789
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06098
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.894588
GTEX-XXEK-0626-SM-4BRWE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41574
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
PMC11825621-210_2024_3353_MOESM2_ESM.xlsx-AR-IL13_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NCCLMS1C1	DepMap CRISPR Gene Dependency	1.0	2.27712
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04843
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52079
FBXW5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.152
SOX2-20726797-SW620-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2661
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47316
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78852
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54551
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
Ciliary pocket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.836
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993962
ATXN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92314
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr6_30927516_A_G_b38	GTEx eQTL 2025	1.0	2.93026
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.256989
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25179
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
BLACAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71428
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.974501
Gestational age at birth (maternal effect)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMCH1	DepMap CRISPR Gene Dependency	1.0	2.83233
TMEM87A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54673
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824907
ZNF346	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40442
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87022
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50453
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29079
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81289
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.8693
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40787
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
saliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61175
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.71193
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40155
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14125
ATP6V0C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24896
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4728
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05823
GTEX-T6MO-0426-SM-32QOI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51828
PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF805	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01826
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.6234
GTEX-SIU7-0526-SM-3NM8I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28277
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7367
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37348
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13016
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06007
extracellular region	GO Cellular Component Annotations 2015	1.0	null
GTEX-PWOO-0726-SM-2I3EB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4236
Tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53176
properties	GeneRIF Biological Term Annotations	1.0	null
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65777
ADAM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1056
alveolar wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.808134
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21107
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HF-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09722
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83424
NCIH1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41971
bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20912
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
Cutaneous lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
RAB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43168
GTEX-XQ8I-1526-SM-4BOOH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11826
behcet syndrome	GAD Gene-Disease Associations	1.0	null
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.40347
viral hepatitis	GWASdb SNP-Phenotype Associations	1.0	1.19766
hsa-miR-324-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Signal peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.188
REDD1_Repression_GDS3558_73_human_Blood Myeloid Cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78691
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10654
gallbladder	HPA Tissue Gene Expression Profiles	1.0	0.860864
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.122275
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5345
av3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
PMC12749580-42003_2025_9274_MOESM5_ESM.xls-Supplementary_Data_2A-Supplementary_Table2A_Full_results_of_the_proteome-wide_MR_in_deCODE_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94225
HCC2935	CCLE Cell Line Gene Expression Profiles	1.0	2.43503
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305361
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.01839
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54357
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14236
PGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13476
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81461
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-11A-11R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.053
Brain Lower Grade Glioma_LGG_TCGA-FG-8185-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system_CT1_alveolar type II cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.947409
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05406
Lupus Erythematosus	DisGeNET Gene-Disease Associations	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984289
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.123729
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9067
Lung-adventitial cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0935361
GSE169205_3_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Vitiligo	DisGeNET Gene-Disease Associations	1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	1.90156
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9071
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-1426-SM-4BONT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45405
Liver-intrahepatic cholangiocyte	Tabula Sapiens Gene-Cell Associations	1.0	-0.0934148
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74301
SNU601	DepMap CRISPR Gene Dependency	1.0	2.73053
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
Respiratory system_CT1_alveolar type I cell	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
ZNF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7203
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80134
GTEX-QMR6-1926-SM-32PL9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95521
Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF414	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12029
GTEX-QLQ7-0926-SM-447BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958734
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936713
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41423
GTEX-QCQG-0626-SM-48U21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963155
GSE62843,GSE64371_4_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40172
GTEX-WY7C-0426-SM-3NB3C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34067
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.003481
GTEX-XV7Q-1126-SM-4BRVS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829164
KPNSI9S	CCLE Cell Line Gene Expression Profiles	-1.0	-1.85471
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01597
PMC7217064-IJC-146-3354-s005.xlsx-Table_S6-Supplementary_Table_S6_Genes_significantly_upregulated_in_OC2-transfected_MKN74_cell_compared_to_control_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.57371
disease	GWASdb SNP-Disease Associations	1.0	0.041849
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11256
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0238
PHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82962
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45067
NDUFB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26284
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047183
Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.664
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3663
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36201
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962681
PHC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51546
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2858
KLK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85734
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63091
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1701
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25267
Alveolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.631
XPO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2247
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25814
TIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54604
Nose disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
SRRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22713
FAHD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41127
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
RAD51AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89282
PMC10175786-Table4.XLSX-Sheet_1-GSE7410_AND_GSE63514_NOT_GSE9750_NOT_Ferrotosis_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-0426-SM-4BRVN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32596
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02004
ZNF696	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.339
Lupus erythematosus	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
SLC25A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24839
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34362
Lung-pulmonary ionocyte	Tabula Sapiens Gene-Cell Associations	1.0	-0.0938997
DNAJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4628
RBM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84485
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36855
TBP	ENCODE Transcription Factor Targets	1.0	null
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79672
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991221
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.53627
GTEX-R53T-1126-SM-48FD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946259
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-05A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNRC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84361
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27994
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46585
NCIH441	CCLE Cell Line Gene Expression Profiles	1.0	1.39077
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95118
MAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19648
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199660_1_v_3_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94866
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9725
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90587
lung	GTEx Tissue Gene Expression Profiles	1.0	2.16463
CCDC9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95649
Kidney Chromophobe_KICH_TCGA-KN-8432-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C4orf36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65416
chr6_30840985_C_T_b38	GTEx eQTL 2025	1.0	1.00697
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046629
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79006
PHF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97412
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88186
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.122275
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
GSE193258,GSE193259_9_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68071
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95875
ADAMTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25943
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GR-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4655
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07091
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4795-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047289
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7364-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-1126-SM-4BOO2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67542
Human - Lung v2 (HLCA) - L2 - Alveolar epithelium	HuBMAP Azimuth Cell Type Annotations	1.0	null
Nasal cavity disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68293
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
HUPT3	CCLE Cell Line Gene Expression Profiles	1.0	1.80979
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.076343
SNRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91666
DNAJC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13568
PITX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66928
HT55	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43514
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.93225
Lung adenocarcinoma_LUAD_TCGA-78-7149-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4728
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936713
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914201
GTEX-Q2AI-0626-SM-48TZU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992926
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78632
Malaria	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
MMP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17215
GTEX-OHPL-0526-SM-3NM8U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32068
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.45891
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.213
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059607
GTEX-SE5C-1126-SM-4BRWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06462
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
abnormality of the liver	GWASdb SNP-Phenotype Associations	1.0	0.316448
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
SEPHS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78893
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8916
ZNF426	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.345
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901444
DPP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6784
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.017
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75568
NEFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72945
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14238
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	3.27055
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37844
HUCCT1	CCLE Cell Line Gene Expression Profiles	1.0	1.56101
ARL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33912
NR1D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08645
TLDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03795
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45798
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058677
SFRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52761
GTEX-O5YV-0526-SM-2I5GE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21252
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3765
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Psoriasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
Bipolar Disorder	DisGeNET Gene-Disease Associations	1.0	null
GATA2_01_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.89121
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.727711
ZNF274	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18775
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.70199
MEC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40699
hepatitis	GWASdb SNP-Phenotype Associations	1.0	0.84496
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95093
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25108
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05667
Stevens-Johnson syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.09
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62361
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29069
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10218
MBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10047
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32895
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56365
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.35
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.60198
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60573
YD8	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60014
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01394
Large cell neuroendocrine carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53273
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60724
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
Disease by infectious agent	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
GTEX-WH7G-0726-SM-3NMBM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58664
GTEX-P4QR-1026-SM-2I5GP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26601
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28291
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06733
Prostate adenocarcinoma_PRAD_TCGA-HC-7081-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.18577
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05735
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39808
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96137
GTEX-O5YT-0526-SM-32PK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33049
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936713
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22952
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86187
NCIH1092	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51236
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatitis B	DisGeNET Gene-Disease Associations	1.0	null
GTEX-N7MT-0326-SM-48TDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06901
PIK3C2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1175
GTEX-NFK9-1126-SM-3LK78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974987
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Respiratory system_CT1_alveolar type II cell	HuBMAP ASCT+B Annotations	1.0	null
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15819
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DL-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RC3H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55941
SDR39U1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52272
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TEF	MotifMap Predicted Transcription Factor Targets	1.0	null
FREY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22373
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48784
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86744
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56968
GTEX-WFJO-0326-SM-3GIL3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45022
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STXBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78572
GTEX-XUJ4-1226-SM-4BOPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02409
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8867
Small cell lung carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89306
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896337
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
SCRT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83542
HT1376	CCLE Cell Line Gene CNV Profiles	1.0	2.2914
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13949
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4177-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64636
Rectum adenocarcinoma_READ_TCGA-AF-3911-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0592
Rad51B-Rad51C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
MTHFS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15163
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053687
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.073468
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PHLDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0961
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39457
CCN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04704
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
GTEX-R3RS-1326-SM-48FE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865212
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98147
HMGN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08779
GTEX-SE5C-1226-SM-4BRWV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96568
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10195
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
unique	GeneRIF Biological Term Annotations	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60967
GTEX-POYW-1326-SM-48TCG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00186
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4597
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995003
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	2.16611
Human - Lung v2 (HLCA) - Finest - AT1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39474
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NS-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hepatitis b	GWASdb SNP-Disease Associations	1.0	1.3711
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.373
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53096
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3408
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
GTEX-U4B1-0826-SM-4DXTW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04433
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
Lupus Erythematosus, Systemic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23011
CCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74936
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3529
GTEX-XYKS-0526-SM-4BRW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53244
ZNF500	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88737
Mucinous adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
TEAD1	JASPAR Predicted Transcription Factor Targets	1.0	null
Sc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
Deuterosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42898
RH41	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37308
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0527
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE183176_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Aids (Disease)	DisGeNET Gene-Phenotype Associations	1.0	null
GSE175787_5_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89135
GTEX-P4QT-0626-SM-3NMCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08536
C2CD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42816
Meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9407
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ciliary pocket collar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10839
OVISE	CCLE Cell Line Gene Expression Profiles	1.0	1.52193
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.91653
eyelid	GeneRIF Biological Term Annotations	1.0	null
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76624
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05511
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835335
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89306
DNAJB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60007
Perturb_11858_KO_Erg|Fli1_SRP402910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.5225
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.44621
MRPL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6804
GTEX-UPK5-1226-SM-4IHL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14687
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1784
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91457
GTEX-V1D1-1026-SM-4JBHE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896289
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
RAD23A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63294
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2258
GTEX-X4LF-0526-SM-3NMB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38748
MRPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93638
SLC10A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24207
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859872
NKX6-1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7536
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051908
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRADC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32698
SRPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43175
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86488
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
KLM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936713
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068717
Bladder Urothelial Carcinoma_BLCA_TCGA-FT-A61P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60759
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
OTX	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80889
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55457
SREBF2	ChEA Transcription Factor Targets	1.0	null
GSE186287_2_v_0_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH2196	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81113
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60296
Lung-smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0936573
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOLM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63961
P2RY11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09275
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F1-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91616
GTEX-U3ZM-0426-SM-3DB73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44137
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A513-01A-12R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48927
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30473
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.23845
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5576-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALKBH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00435
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A8OD-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.56981
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09054
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46262
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.30264
hsa-miR-4459	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8393
Brain Lower Grade Glioma_LGG_TCGA-HT-A4DV-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHACTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47187
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05817
PARD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76956
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83861
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05668
KIF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33122
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0212
ERLIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42523
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
Spindle pole body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.272
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6208
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung adenocarcinoma_LUAD_TCGA-73-4677-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14155
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12959
Respiratory allergy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.532
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
Infantile liver failure syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
CTCF	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75349
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880556
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
immunodeficiency	GWASdb SNP-Phenotype Associations	1.0	0.913571
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60162
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A721-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Behcet Syndrome	dbGAP Gene-Trait Associations	1.0	0.31538
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05406
Coronary artery smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
ZBTB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26647
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
GTEX-WEY5-0926-SM-4LMI4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889452
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
NUCKS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16896
HCE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
35 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
A253	DepMap CRISPR Gene Dependency	1.0	2.15588
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31316
GSE131161_5_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40163
Hiv-1, Resistance To	DisGeNET Gene-Phenotype Associations	1.0	null
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31487
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF540	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12236
GTEX-WHSB-0326-SM-3LK6K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51755
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51784
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51855
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
Swine influenza	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
membrane coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.453223
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824907
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98915
Lung-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0937785
A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.34569
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859872
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22333
FDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98708
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5159
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
GSE186633_1_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
Human - Lung v2 (HLCA) - L3 - AT1	HuBMAP Azimuth Cell Type Annotations	1.0	null
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36129
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12511
Brain Lower Grade Glioma_LGG_TCGA-P5-A730-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clathrin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.543587
ARPP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30207
URGCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5021
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3112
MOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44572
ACSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16653
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28442
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15064
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3255
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64757
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13466
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939323
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42137
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05406
19962670-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S32W-0926-SM-4AD5X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861446
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWS6-0226-SM-2XCA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42772
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.6501
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.986234
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0527
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2038
HOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4934
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
CDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37921
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08641
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.585
CFPAC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65947
GTEX-P4PP-1526-SM-3P61M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82407
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03762
TOP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4309
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58459
FGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80797
GSE139455_0_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839554
USF1	JASPAR Predicted Transcription Factor Targets	1.0	null
PCDH18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
CBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74077
UHRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23322
GTEX-P4PP-0626-SM-3NM9X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857548
Lung-bronchial smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0938997
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928881
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865463
RBM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71002
CEBPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1352
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88683
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.963284
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47646
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14125
Membranous glomerulonephritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
EIF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45553
chr6_31037362_G_A_b38	GTEx eQTL 2025	1.0	2.29717
AKAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82477
NCIH1869	CCLE Cell Line Gene Expression Profiles	1.0	2.28105
Human - Lung v2 (HLCA) - Finest - AT2	HuBMAP Azimuth Cell Type Annotations	1.0	null
Alveolar sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.59
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849975
Acute Myeloid Leukemia_LAML_TCGA-AB-2976-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15205
MXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.24138
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36343
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06748
Submucosal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
FAM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85166
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11529
ENTPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26604
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
SREBP2-21459322-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KIF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8261
20421987-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2318
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4159
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5582
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67922
PMC7431913-Table_1.xls-Sheet1-TablesS1_Gene_clusters_highly_co-expressed_with_MNX1_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AAGAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77462
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18018
U2OS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87089
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
gingiva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.657054
SQ1	CCLE Cell Line Gene Expression Profiles	1.0	2.55025
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
EMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12962
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	63.3095
RNF103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03498
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1329
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZN-0626-SM-3DB7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32246
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81369
Bronchiolar epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71114
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
Lung adenocarcinoma_LUAD_TCGA-78-7156-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Viral infectious disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.672
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2081
GTEX-TML8-1526-SM-4DXUX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934887
PIK3R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86333
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80291
KNS62	CCLE Cell Line Gene CNV Profiles	1.0	1.83596
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.224989
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969087
GLCCI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58724
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936713
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6123
GSE193258,GSE193259_2_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S4Q7-0426-SM-3K2BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40914
L1236	CCLE Cell Line Gene CNV Profiles	1.0	1.45102
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMSB15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01922
SMIM29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78767
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042552
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oropharynx cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
TMEM138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18894
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
POLR2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45068
GSE231648_4_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20696
viral infectious disease	GWASdb SNP-Disease Associations	1.0	0.424291
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64395
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7007-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1287
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70287
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.38772
PPP1R1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10454
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93435
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Attention Deficit Disorder	DisGeNET Gene-Disease Associations	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2427
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28552
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68043
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
PLCXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25405
GSU	DepMap CRISPR Gene Dependency	1.0	2.37006
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
GTEX-SNMC-0626-SM-4DM6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874813
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05123
FAM234B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13901
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40163
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86595
artery disease	GWASdb SNP-Disease Associations	1.0	0.090775
GTEX-N7MT-1926-SM-3LK5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05312
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96454
LRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2312
HNF1	MotifMap Predicted Transcription Factor Targets	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.4126
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
SW1990	CCLE Cell Line Gene CNV Profiles	1.0	1.88873
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072218
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.703
KYSE150	CCLE Cell Line Gene CNV Profiles	1.0	1.63308
Hydrocephalus	DisGeNET Gene-Disease Associations	1.0	null
PMC8901773-41598_2022_7986_MOESM3_ESM.xls-PIO_vs_LPS-Gene_symbol_ENSEMBL_ID_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-1626-SM-4BONV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01096
TEN	CCLE Cell Line Gene Expression Profiles	1.0	1.93457
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7425
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RRAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40371
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TOPORS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74634
GTEx Lung 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-6.50164
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29452
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.622
Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05362
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.2516
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23331
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973196
UBR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838725
Cervix disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
CDK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4569
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A40E-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QS-0526-SM-2I3ET	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43474
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01562
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05406
Perturb_13262_KO_chr9_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.95441
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
Coronary Heart Disease	DisGeNET Gene-Disease Associations	1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.146516
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96322
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
RAB35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.756
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38274
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
C6orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27733
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
HINT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80528
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03107
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49941
VAC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53464
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.374243
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25814
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86659
BAMBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37152
clathrin coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.489327
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.100618
Lung squamous cell carcinoma_LUSC_TCGA-22-5491-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78352
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9651
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
GTEX-T5JC-0826-SM-32PMC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20325
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EPRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40617
GTEX-OXRN-0526-SM-2I5EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35666
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58088
KDM4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37813
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36504
Small Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
BACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6649
Coronary artery smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
TCF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46843
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1794
MAP2K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
Lung squamous cell carcinoma_LUSC_TCGA-56-7222-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20054
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93236
TSTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59125
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12511
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06882
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92574
CCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84334
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22241
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942745
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83653
GTEX-PLZ5-0926-SM-3TW8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0081
SMARCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66486
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04843
Complete Atrioventricular Block	DisGeNET Gene-Disease Associations	1.0	null
D542MG	DepMap CRISPR Gene Dependency	1.0	2.38624
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18716
MYCN-19997598-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
IDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88101
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854138
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886997
HYCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878968
GTEX-XYKS-1526-SM-4BRUP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967751
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5937
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67732
RTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
Colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25211
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60559
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.197095
secretory	GeneRIF Biological Term Annotations	1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.841
GTEX-UJHI-0826-SM-4IHLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961787
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53496
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35267
Female reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.14946
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61602
Perturb_17454_KO_Insr/Igf1r_SRP091479	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.9037
Acute Myeloid Leukemia_LAML_TCGA-AB-3005-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-2.04539
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
HEYL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0443
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9072
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82549
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.61383
colorectum	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7885-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21934
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14567
IDH3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69418
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.863983
PIGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71601
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64218
Tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956487
vasculitis	GWASdb SNP-Disease Associations	1.0	0.41379
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16784
THAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73337
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
VPS26C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44212
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C1orf122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68799
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GAMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58247
GTEX-XGQ4-0826-SM-4AT4T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48147
BTN3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7059
bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.847065
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29836
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951178
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2709
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52442
GTEX-XMK1-1326-SM-4B65Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02931
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6155
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85476
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
NCIH2342	CCLE Cell Line Gene Expression Profiles	1.0	1.77135
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Graves' disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.549
SP140L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93414
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2318
Arthritis, Psoriatic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56096
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12061
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48223
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.473
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24897
METTL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50846
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936713
NDUFB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63739
PSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88989
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7084
COV413A	DepMap CRISPR Gene Dependency	1.0	2.06349
alveolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.610943
BEND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4728
GSE195663_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043024
alveolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.847065
MEOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7695
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928881
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0377
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SELENON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60743
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.59019
DMS53	DepMap CRISPR Gene Dependency	1.0	2.16718
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
MXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98131
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03552
ID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68426
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6916
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063957
Alveolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
SUSA	DepMap CRISPR Gene Dependency	1.0	2.00613
TBRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5025
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.8063
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90446
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.541
PRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82138
colon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49244
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L540	CCLE Cell Line Gene CNV Profiles	1.0	1.58196
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0369
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15153
Lung squamous cell carcinoma_LUSC_TCGA-77-7337-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55G-0826-SM-2TC5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55875
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2653
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99563
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64439
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.18945
Lung epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81345
Female reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8851
Eye-ciliary body	Tabula Sapiens Gene-Cell Associations	1.0	-0.0938997
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824907
TT2609C02	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92562
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.549
GSE221539_1_v_0_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UNC5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02985
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55817
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.16406
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16509
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44904
PLPPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02208
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64148
ZBTB40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42044
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
GTEX-WFON-0826-SM-4LVMI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910283
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RORB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81535
NUDT17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6917
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053361
GTEX-OIZI-1026-SM-3NB1K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44587
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90801
HCC56	DepMap CRISPR Gene Dependency	1.0	2.42432
Uterine cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.294
GTEX-T6MO-0526-SM-4DM6R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24202
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.769
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7159
ITPRIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8571
ARL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55874
CNIH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40134
GTEX-P4PQ-0626-SM-3NMCU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05809
GSE193258,GSE193259_2_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74553
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.120327
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0837
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5603
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47456
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27416
highly	GeneRIF Biological Term Annotations	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90446
HNF1A-26855178-CACO2-HUMAN-COLON-ADENOCARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
FAM50B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66145
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96382
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94385
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49656
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.34585
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89321
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61736
HOXD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5558
SYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66835
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
Alveolar epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.254
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08695
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEC1A	CCLE Cell Line Gene Expression Profiles	1.0	1.70616
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
TWIST1_01_254	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59508
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.984246
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08163
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06739
Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3395
NPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65517
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92575
DND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06314
Myasthenia Gravis	DisGeNET Gene-Disease Associations	1.0	null
Salivary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
NCIH3255	CCLE Cell Line Gene Expression Profiles	1.0	3.40851
PROSER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15998
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047419
ACTRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4735
PBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32791
GTEX-WFG8-0926-SM-3GIKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47692
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41374
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.038404
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86633
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73528
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852066
GTEX-QDVJ-0926-SM-2I5FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45188
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47204
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5567-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.064973
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12798
Alveolar wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.585
GTEX-TMMY-0926-SM-33HBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27948
HSPB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34596
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70632
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2597
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842762
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23421
GSE207914_5_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X3Y1-0626-SM-3P5YS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12323
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7167-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49826
JMURTK2	DepMap CRISPR Gene Dependency	1.0	2.31779
GTEX-U4B1-1026-SM-4DXT1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852991
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GTEX-T2IS-0826-SM-4DM6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85687
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27647
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07529
Colon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC1171	CCLE Cell Line Gene Expression Profiles	1.0	1.38164
GTEX-XBEW-1326-SM-4AT63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10591
SPOPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49971
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02915
GTEX-Q2AH-1126-SM-48TZM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849532
SEBOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42249
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76867
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20759
TRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22333
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32178
GTEX-SE5C-0526-SM-2XCE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30151
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.383
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851186
GTEX-UPIC-1426-SM-4IHLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844835
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	2.13669
coated membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.439333
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
lung	HPA Tissue Gene Expression Profiles	1.0	1.42326
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8659
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.961
HS863T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89813
HLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21211
IGFBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01027
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.63102
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bronchus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.560847
PDZD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76407
Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Terminal bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
MYD88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77831
JIMT1	DepMap CRISPR Gene Dependency	1.0	2.09303
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10269
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04224
GTEX-OXRL-0626-SM-3NM9C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880029
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47748
PMC9437810-mmc6.xlsx-Sheet1-Table_S8_Significant_isoform_switches_unique_to_BE_LGD_TP53_WT_vs_BE_HGD_TP53_MUT_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5356-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054892
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
Surfactant-associated protein 2	InterPro Predicted Protein Domain Annotations	1.0	null
tear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28278
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
T173	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53204
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89744
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46554
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.922
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74867
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38163
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
GTEX-R55D-0926-SM-3GAEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53886
MELJUSO	DepMap CRISPR Gene Dependency	1.0	2.04563
KHSRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90412
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10596
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59555
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7947
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
human immunodeficiency virus infectious disease	GWASdb SNP-Disease Associations	1.0	1.04096
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87015
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
esophagus	GTEx Tissue Gene Expression Profiles	1.0	1.00727
PMC11373733-ABR-13-34_Suppl1.pdf-177-SETDB1_SETDB1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0426-SM-3GIL4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50854
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.072218
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60967
PMC7880379-aging-13-202285-s003.xlsx-DElncRNA_target-FEZF1_FEZF1	Rummagene Transcription Factor Associations 2026	1.0	null
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837131
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.062
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VZ-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93741
PLAGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45673
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.896652
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51177
NEMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58591
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1995
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.061804
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.55
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7615
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7422
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61054
large intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NUP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52266
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074789
NCIH2286	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41099
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.712
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71858
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.824907
PLPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972691
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
CHEK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18123
SOX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53983
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09827
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8813
Brain Lower Grade Glioma_LGG_TCGA-QH-A65Z-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51347
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RHOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92389
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14621
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16784
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80984
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.956
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7839
GTEX-PX3G-0526-SM-2I3EM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40397
ENOPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72579
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05518
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74625
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41178
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24526
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73116
ANO9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43476
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12582692-medi-104-e45093-s001.xlsx-Table_S1-Table_S1_Genetic_instruments_of_plasma_proteins_for_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null