association dataset threshold value standardized value abnormality of the eye HPO Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A72U-01A-31R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_14864_KD_ZRSR2_SRP341591 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.8921 fluorouracil_mus musculus_gpl81_gds771 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NARF Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-A5G8-01B-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMC1 MSigDB Cancer Gene Co-expression Modules 1.0 null IM-95 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PWO3-0005-SM-2I5FS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.967129 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895439 H3K27ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-CL-5918-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Squamous Cell Carcinoma Of Skin DisGeNET Gene-Disease Associations 1.0 null Coma CTD Gene-Disease Associations 1.0 1.21534 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.52668 CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null VI, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08902 semen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.707631 cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.26239 primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0062 H3K79me2_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058067 dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.34372 GTEX-OIZF-0006-SM-2I5GQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05152 muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044549 bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.59894 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042137 IX Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.837065 olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.934486 CAL120 Achilles Cell Line Gene Essentiality Profiles 1.0 1.17151 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12581 periventricular stratum of m1AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06556 Perturb_6048_KD_PIAS2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Perturb_17226_KO_lincBrn1b_SRP028547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GTF3C2 ENCODE Transcription Factor Targets 1.0 null TRIM33 Pathway Commons Protein-Protein Interactions 1.0 null reproductive organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.115608 familial GeneRIF Biological Term Annotations 1.0 null CUL1 Pathway Commons Protein-Protein Interactions 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967338 PHF8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84079 immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.452585 intermediate stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44856 Necrosis CTD Gene-Disease Associations 1.0 1.85362 ETS1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10406 GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.37866 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.930212 r8 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.02879 neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.053133 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.04026 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1106 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null muscle benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.120024 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3730_KO_Atf7ip_SRP327190 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.87969 GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.83374 FLI1 ChEA Transcription Factor Targets 1.0 null abnormality of the uvea HPO Gene-Disease Associations 1.0 null brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ENCODE Transcription Factor Targets 1.0 null HTT ChEA Transcription Factor Targets 1.0 null PRPF4B Pathway Commons Protein-Protein Interactions 1.0 null cardiovascular system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 periventricular stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01543 MALME3M CCLE Cell Line Gene CNV Profiles 1.0 1.41738 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.315366 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909632 H3K4me3_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null leg TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.094828 GTEX-S7SF-0426-SM-3K2B7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02638 H3K36me3_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null p3x63ag8 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.67658 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.98912 REST_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.15817 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null culture medium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.317679 GTEX-XBED-0006-SM-47JXO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4046 membrane-enclosed lumen COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.903863 SAOS2 BioGPS Cell Line Gene Expression Profiles 1.0 1.24281 hsa-miR-4719 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.895283 HA-E2F1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null tuberculosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.074663 nicotine_myzus persicae_gpl9470_gse18658 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.24368 POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBE2I Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PTHrP_KD_GDS1664_438_human_MDA-MB-231 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me3_G1E_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null skin GeneRIF Biological Term Annotations 1.0 null inner CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30501 nb4 HPA Cell Line Gene Expression Profiles 1.0 1.25009 Cmah_KO_GDS4770_421_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -2.95637 SOX2-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MET_knockout_256_GSE25583 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.48702 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03877 congenital nervous system abnormality DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.118074 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RUNX3 ENCODE Transcription Factor Targets 1.0 null GTEX-NL3H-0011-R7a-SM-2I3G5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889181 GTEX-U412-0226-SM-3NMC8 GTEx Tissue Sample Gene Expression Profiles 1.0 0.890785 vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.233878 Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66585 IGROV1_OVARY CCLE Cell Line Proteomics 1.0 3.70231 TAF1_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.866044 POLR2A_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63622 diagonal part of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08932 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0469 cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.30974 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01071 binds GeneRIF Biological Term Annotations 1.0 null GTEX-WH7G-2026-SM-3NMBL GTEx Tissue Sample Gene Expression Profiles 1.0 0.89405 GTEX-XUJ4-0005-SM-4BOQ6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27209 Crus 1, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82503 GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34403 Perturb_4789_KD_Firre_ERP009127 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.53076 CCT8 Hub Proteins Protein-Protein Interactions 1.0 null GTEX-WFJO-0826-SM-4LVM5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.842368 SMARCA4 ChEA Transcription Factor Targets 1.0 null GTEX-SIU8-0006-SM-2XCE5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2421 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84863 RAD23A MSigDB Cancer Gene Co-expression Modules 1.0 null Ovarian Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48351 LUDLU1 CCLE Cell Line Gene CNV Profiles 1.0 1.35666 CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dna recombination GO Biological Process Annotations 2015 1.0 null UBLCP1 Pathway Commons Protein-Protein Interactions 1.0 null cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32416 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.844766 H3K27ac_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.951951 DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.944466 SP1 ENCODE Transcription Factor Targets 1.0 null absent hand HPO Gene-Disease Associations 1.0 null NCIH1339 CCLE Cell Line Gene Expression Profiles -1.0 -1.84311 NCIH1568_LUNG CCLE Cell Line Proteomics 1.0 2.69979 15902281-TableS1d GeneSigDB Published Gene Signatures 1.0 null Platinum Measurement DisGeNET Gene-Phenotype Associations 1.0 null pseudopodium COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.278509 GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15551 ADAP2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00606008 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10667 Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null toe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.256568 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 2.34899 single-organism cellular process GO Biological Process Annotations 2015 1.0 null Perturb_1788_KO_Irf8_SRP265303 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.53548 BRCA1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17954 GTEX-XUZC-2126-SM-4BRW8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.12528 MDA-MB-453 GDSC Cell Line Gene Expression Profiles -1.0 -2.56598 GTEX-XQ3S-0001-SM-4B64K GTEx Tissue Sample Gene Expression Profiles 1.0 1.48966 GTEX-R3RS-1326-SM-48FE7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.957465 PRRC2A Pathway Commons Protein-Protein Interactions 1.0 null Fetal_Brain_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.00207 HNF4A Pathway Commons Protein-Protein Interactions 1.0 null r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.57176 inner CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02289 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 0.955286 pectoral fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.408972 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19475 layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15222 GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47728 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00793 H3K27ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null gata4_18812176_jejunum_tissue_lof_mouse_gpl1261_gds3486 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.164342 15273739-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null POLR2A_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7DU-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-PX3G-1026-SM-48TZW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.872461 Perturb_9529_KO_Clock_SRP252642 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.93427 GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34511 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WHSB-0005-SM-3LK7C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58889 Cervical Cancer DisGeNET Gene-Disease Associations 1.0 null YY1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -3.06501 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney Diseases CTD Gene-Disease Associations 1.0 1.79981 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03877 CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null shorter GeneRIF Biological Term Annotations 1.0 null POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS ENCODE Transcription Factor Targets 1.0 null liver_a HPA Tissue Sample Gene Expression Profiles 1.0 2.1099 nuclear part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 studied GeneRIF Biological Term Annotations 1.0 null GTEX-X5EB-0526-SM-46MVP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.848097 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.056861 Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Congenital Abnormalities CTD Gene-Disease Associations 1.0 1.1014 liminal periaqueductal gray of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01662 POLR2A_K562_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleoplasm part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 JUN_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus II, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00329 GTEX-NPJ8-0226-SM-48TBN GTEx Tissue Sample Gene Expression Profiles 1.0 1.26738 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045746 H3K18ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null external female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.161452 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.67937 Perturb_50_KO_Kat6a_SRP215863 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.17672 superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95324 gemcitabine_homo sapiens_gpl96_gse6914 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8094-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16176 arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.90103 BCLAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1795_KD_Bud13_SRP168625 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.25302 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.770685 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46431 SETDB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.127228 reliable GeneRIF Biological Term Annotations 1.0 null GTEX-QESD-1426-SM-2S1R9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00767 TAF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BCLAF1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.60875 inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.997994 bone marrow TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072502 Superior vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67073 cauda epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.228764 all GWASdb SNP-Phenotype Associations 1.0 0.028039 H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PSMA2 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-8494-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleic acid metabolic process GO Biological Process Annotations 2015 1.0 null Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05046 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null LS 180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.849146 gonadotrophic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.36825 internal male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.764468 TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.059267 LTN1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 1.54774 pronephros TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ChIP_ASH2L_23239880 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Type 2 diabetes mellitus_Renal Tissue_GSE642 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.73821 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.05663 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.28573 GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -2.30364 GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31624 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Breast Carcinoma DisGeNET Gene-Disease Associations 1.0 null GTEX-X4LF-0006-SM-3NMCO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.5587 GTEX-XBED-0003-SM-47JWP GTEx Tissue Sample Gene Expression Profiles 1.0 1.38584 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TAF1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.87579 GTEX-WFG7-1126-SM-4LMK3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.866886 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RUNX2 ChEA Transcription Factor Targets 1.0 null GTEX-Q2AH-0008-SM-48U2J GTEx Tissue Sample Gene Expression Profiles 1.0 1.18923 CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AML193 CCLE Cell Line Gene Expression Profiles 1.0 1.67942 PSMC6 Pathway Commons Protein-Protein Interactions 1.0 null RCOR1-19997604-NEURONS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null BOC LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00756068 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.851419 LAMA2_Deficiency_GDS3371_595_mouse_Hind limb skeletal muscle (4-week old dy3K/dy3K animals) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 aplasia involving bones of the extremities HPO Gene-Disease Associations 1.0 null limb bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306805 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal thalamus_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.7351 GTEX-O5YT-0126-SM-48TBW GTEx Tissue Sample Gene Expression Profiles 1.0 1.30614 recombinational repair GO Biological Process Annotations 2015 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MYC_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.09249 motif GeneRIF Biological Term Annotations 1.0 null alimentary canal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-PX3G-2426-SM-48TZZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.92909 GTEX-XXEK-0004-SM-4BRWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.40812 ASPC1 CCLE Cell Line Gene CNV Profiles 1.0 2.22742 CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null single-organism metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.886208 Perturb_15394_KD_RRM2_SRP155857 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.01279 HNF4A-19822575-HepG2-human ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20923 Periventricular hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14455 Perturb_5944_KD_PPAN_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.7246 organ system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.33066 H3K14ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC63 Hub Proteins Protein-Protein Interactions 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.28367 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80224 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3947 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91112 hematopoietic cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065167 GTEX-O5YT-0007-SM-32PK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12846 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EGR1 ENCODE Transcription Factor Targets 1.0 null GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.6291 Perturb_12049_KO_LSD1_SRP310135 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056869 GTEX-W5WG-0008-SM-4KL25 GTEx Tissue Sample Gene Expression Profiles 1.0 0.837761 POLR2A_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null breast GeneRIF Biological Term Annotations 1.0 null dss1 GeneRIF Biological Term Annotations 1.0 null GTEX-RTLS-0008-SM-48FET GTEx Tissue Sample Gene Expression Profiles 1.0 0.839042 NCI-H1993 GDSC Cell Line Gene Expression Profiles 1.0 2.56825 OE33 CCLE Cell Line Gene Expression Profiles 1.0 1.56283 POLR2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the ear HPO Gene-Disease Associations 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22225 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GABPA_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pain CTD Gene-Disease Associations 1.0 1.33228 Vomiting CTD Gene-Disease Associations 1.0 1.23392 BAG1 Pathway Commons Protein-Protein Interactions 1.0 null dexamethasone_mus musculus_gpl6105_gse44208 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null FEN1 Pathway Commons Protein-Protein Interactions 1.0 null HCC1187 Achilles Cell Line Gene Essentiality Profiles 1.0 1.11271 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 been GeneRIF Biological Term Annotations 1.0 null Arrhythmogenic Right Ventricular Cardiomyopathy_Myocardial tissue_GSE4120 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.50847 SKOV3 BioGPS Cell Line Gene Expression Profiles -1.0 -1.1006 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD1 Pathway Commons Protein-Protein Interactions 1.0 null leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.341863 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52763 components GeneRIF Biological Term Annotations 1.0 null GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles 1.0 0.952834 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.3612 EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null variant GeneRIF Biological Term Annotations 1.0 null ETS1-20019798-JURKAT-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044127 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.12994 HCFC1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bone marrow cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.093751 EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null placental site trophoblastic tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.782707 hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.16472 bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044976 syndactyly HPO Gene-Disease Associations 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046318 ovarian cyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.271952 Abnormalities, Drug-Induced CTD Gene-Disease Associations 1.0 1.04904 H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null INTS8 Pathway Commons Protein-Protein Interactions 1.0 null tail of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.52747 ARID3A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0526-SM-4DM56 GTEx Tissue Sample Gene Expression Profiles 1.0 0.857408 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05278 physical disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.592116 H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_15395_KD_RB1_SRP271262 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 CHD7 ENCODE Transcription Factor Targets 1.0 null GTEX-P4PP-1026-SM-3NM9O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855681 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36895 CREB1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null bone disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.842276 GTEX-SSA3-0002-SM-3P61R GTEx Tissue Sample Gene Expression Profiles 1.0 0.870337 hyperprolactinemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.718846 posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.78102 reuniens nucleus (medioventral nucleus) of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.19254 mantle zone of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04896 POLR2A_K562_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.99659 relapsefree GeneRIF Biological Term Annotations 1.0 null GTEX-W5X1-0826-SM-3GILN GTEx Tissue Sample Gene Expression Profiles 1.0 1.20337 GTEX-P4QR-0006-SM-2I5GN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.986765 Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null CEBPB-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YY1 Pathway Commons Protein-Protein Interactions 1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMEC Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.88795 Tumor Progression DisGeNET Gene-Phenotype Associations 1.0 null RAD23A Pathway Commons Protein-Protein Interactions 1.0 null TE-5 GDSC Cell Line Gene Expression Profiles 1.0 1.64071 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.3577 frontalcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.95399 plasmacytoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.191015 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sirolimus_homo sapiens_gpl96_gds2494 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null PSMF1 Pathway Commons Protein-Protein Interactions 1.0 null 19636063-TableS6 GeneSigDB Published Gene Signatures 1.0 null connective tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.07516 FOXO3-22982991-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MAX_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null musculoskeletal system benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.071451 Lung adenocarcinoma_LUAD_TCGA-64-1677-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QXCU-0006-SM-2TC5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02031 SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPIC-0726-SM-3GADW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.90894 GTEX-OOBJ-1026-SM-3NB2L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.934084 skeletal muscle HPA Tissue Gene Expression Profiles 1.0 0.954739 Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6985 H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Hyperplasia CTD Gene-Disease Associations 1.0 1.75221 shfm1 GeneRIF Biological Term Annotations 1.0 null GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870544 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38145 UBQLN2 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALL-PO GDSC Cell Line Gene Expression Profiles -1.0 -1.65193 Malignant Tumor Of Cervix DisGeNET Gene-Disease Associations 1.0 null H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null CORL88_LUNG CCLE Cell Line Proteomics 1.0 2.74378 GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.02072 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null adenofibroma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.584719 thyroid cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.272997 RBM15B Pathway Commons Protein-Protein Interactions 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6413_KO_TP53_SRP274402 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.9134 MALME 3M BioGPS Cell Line Gene Expression Profiles 1.0 1.14666 gallbladder_5c HPA Tissue Sample Gene Expression Profiles -1.0 -0.977741 CCDC39 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NELFE_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.13737 hsa-miR-548o TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49651 ventrolateral prefrontal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01286 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null GABPA_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r2 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06207 regulation of transcription by RNA polymerase II GO Biological Process Annotations 2023 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55326 SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.989516 NCIH441 Achilles Cell Line Gene Essentiality Profiles 1.0 2.25709 dorsolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.901254 Depressive Disorder CTD Gene-Disease Associations 1.0 1.1753 REST_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial part of arcuate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50309 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT4 MotifMap Predicted Transcription Factor Targets 1.0 null diencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX5-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051573 renal tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.085426 CREB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null INTS2 Pathway Commons Protein-Protein Interactions 1.0 null reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.22128 JUND_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.31321 POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HS-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null IM-95M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.84541 POLR2A_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5917_KD_HNRNPL_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.72094 H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Melanoma DisGeNET Gene-Disease Associations 1.0 null NFIC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CREB1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null radioulnar synostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.804026 nucleoplasm part GO Cellular Component Annotations 2015 1.0 null YY1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sulindac sulfide-308 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Colorectaladenocarcinoma BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.44858 H4K20me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55659 Precancerous Conditions CTD Gene-Disease Associations 1.0 1.54159 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4046 GSS CCLE Cell Line Gene CNV Profiles -1.0 -1.7764 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01868 H3K36me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1 JASPAR Predicted Transcription Factor Targets 1.0 null 59M CCLE Cell Line Gene Expression Profiles -1.0 -3.1714 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00117 HS 675.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.171 multidrug-resistant tuberculosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.420266 THAP1 ENCODE Transcription Factor Targets 1.0 null GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846809 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67A-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XUYS-0005-SM-47JZ2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17282 TYKNU CCLE Cell Line Gene Expression Profiles 1.0 1.39225 SP2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACHE_OE_GDS891_241_mouse_Prefrontal cortex GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32442 inner ear disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.22145 POLR2A_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS2_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LAMA84 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.37572 zfx_17448993_embryonic_stem_cell_lof_mouse_gpl1261_gds2718 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.898988 PSME2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PWOO-0008-SM-48TDU GTEx Tissue Sample Gene Expression Profiles 1.0 0.836977 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.12381 CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BHLHE40 ENCODE Transcription Factor Targets 1.0 null ectrodactyly HPO Gene-Disease Associations 1.0 null germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.675357 NCI-H520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854125 Neoplasm Metastasis CTD Gene-Disease Associations 1.0 1.45168 mediodorsal nucleus of thalamus_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.850666 H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-MM-A564-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null putamen, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.959024 b-lymphocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.178315 C32 GDSC Cell Line Gene Expression Profiles 1.0 1.5657 H3K4ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIN3A ENCODE Transcription Factor Targets 1.0 null fetus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068343 POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cancers GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.84209 GTEX-OXRO-0011-R9A-SM-3NB1X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.958611 NEDD8 Pathway Commons Protein-Protein Interactions 1.0 null ARID3A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid_5c HPA Tissue Sample Gene Expression Profiles -1.0 -0.85445 MET_knockout_257_GSE25583 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.14371 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.85815 PCID2 Pathway Commons Protein-Protein Interactions 1.0 null embryonic structure TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-30c-5p MiRTarBase microRNA Targets 1.0 null substantianigra BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.840865 UNG MSigDB Cancer Gene Co-expression Modules 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null GTEX-O5YV-1126-SM-3LK73 GTEx Tissue Sample Gene Expression Profiles 1.0 0.879483 inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.952473 PHF8-20622854-HELA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49318 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.71632 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-XV7Q-0226-SM-4BRVL GTEx Tissue Sample Gene Expression Profiles 1.0 1.21287 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.0134 all HPO Gene-Disease Associations 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.08811 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.573828 HCC1833_LUNG CCLE Cell Line Proteomics 1.0 6.00534 H3K27ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 17660535-TableS4c GeneSigDB Published Gene Signatures 1.0 null TAF1 Pathway Commons Protein-Protein Interactions 1.0 null TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.64891 superficial stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06207 RAD21-21589869-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.951007 FOSL2 ENCODE Transcription Factor Targets 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41456 sirolimus_homo sapiens_gpl8300_gds3603 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null rna GeneRIF Biological Term Annotations 1.0 null amygdaloid complex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.86412 H3K14ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.914246 H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TRIM21 Hub Proteins Protein-Protein Interactions 1.0 null 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.7749 H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XGQ4-0004-SM-4AT5S GTEx Tissue Sample Gene Expression Profiles 1.0 0.99907 HCC1569 CCLE Cell Line Gene Expression Profiles 1.0 1.54304 GTF2F1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.956278 GTEX-S7PM-0006-SM-3NM8C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28667 SIN3A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ4-0926-SM-2S1OI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877189 inner CP in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.834497 TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37645 H3K4me3_K562_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TBP_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ8-0011-R1a-SM-33HCB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.948608 vitamin e_mus musculus_gpl1261_gse42813 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC2_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r1 part of the 'mesencephalic' trigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.04395 r1 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28683 mycophenolate mofetil_homo sapiens_gpl4133_gse45485 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null cellular response to dna damage stimulus GO Biological Process Annotations 2015 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null stratum oriens of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825445 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null fluoxetine_mus musculus_gpl1261_gse35761 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null JUN-27471255-CHONDROCYTES-MOUSE-RIB ChEA Transcription Factor Targets 2022 1.0 null HUVEC Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.79999 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68008 Parabrachial nucleus, lateral division, external lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21907 CLPP_KO_GDS4791_107_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-WYVS-0006-SM-3NMA7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1567 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HTT-18923047-STHdh-human ChEA Transcription Factor Binding Site Profiles 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.294748 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.39765 PIAS1 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38954 GTEX-NPJ8-0126-SM-2YUNR GTEx Tissue Sample Gene Expression Profiles 1.0 1.49819 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.79942 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.889781 TCF12 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VK-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null recombinational repair GO Biological Process Annotations 2023 1.0 null Parabrachial nucleus, lateral division, superior lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13973 ovarian mucinous adenofibroma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.64397 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.845418 reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 ovarian follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.746277 EP300_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VUSH-0004-SM-3P61T GTEx Tissue Sample Gene Expression Profiles 1.0 3.32211 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43239 GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 1.00214 GTEX-X261-0011-R6B-SM-4E3J8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.832698 USF1 ENCODE Transcription Factor Targets 1.0 null organelle LOCATE Curated Protein Localization Annotations 1.0 null CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-668 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06951 H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null STUB1 Pathway Commons Protein-Protein Interactions 1.0 null BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.788418 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.96088 double-strand break repair via homologous recombination GO Biological Process Annotations 2023 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bonemarrow_5a HPA Tissue Sample Gene Expression Profiles -1.0 -2.25229 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.916983 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.941218 layer 1 of VPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20718 COLO 680N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.968024 GTEX-XMK1-1326-SM-4B65Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.20116 CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-N7MS-1626-SM-3LK5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.17874 VIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.963183 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Uvula (IX) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0375 GTF2B ENCODE Transcription Factor Targets 1.0 null G61 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.89913 TAF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3427 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1989 tardbp_19910924_hek293e_lof_human_gpl570_gds3730 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.244159 T98G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89532 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.99198 POLR2A_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23078 nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.231448 MAZ ENCODE Transcription Factor Targets 1.0 null ES8 GDSC Cell Line Gene Expression Profiles 1.0 2.44845 Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null LTBR_INHIBITION - 27 Day_GDS2004_736_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-WFG7-0326-SM-3GILI GTEx Tissue Sample Gene Expression Profiles 1.0 0.895936 SUM 159PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.3885 H2BK120ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TE5 CCLE Cell Line Gene CNV Profiles 1.0 1.67972 Lung adenocarcinoma_LUAD_TCGA-05-4395-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null connecting stalk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.088836 RAGE_knockout_267_GDS3755 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.46548 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19198 E2F6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the iris HPO Gene-Disease Associations 1.0 null Neoplasms, Multiple Primary HuGE Navigator Gene-Phenotype Associations 1.0 null detection GeneRIF Biological Term Annotations 1.0 null Perturb_14235_KO_Tet1_SRP237910 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.16272 striatum_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0469 disequilibrium GeneRIF Biological Term Annotations 1.0 null H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54249 inhibin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.707482 CBX3_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUG1N Achilles Cell Line Gene Essentiality Profiles 1.0 1.18327 PSMC3 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ5-0326-SM-3P614 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15461 Perturb_330_KD_MCM7_SRP258965 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.36158 GTEX-XUJ4-0004-SM-4BOQE GTEx Tissue Sample Gene Expression Profiles 1.0 1.69272 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.07466 POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.949434 mccune albright syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.178126 digestive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069236 HDAC2 MSigDB Cancer Gene Co-expression Modules 1.0 null Uvula (IX), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08693 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32815 SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 0.922435 GTEX-U3ZN-2226-SM-3DB88 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16148 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.66255 Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null shown GeneRIF Biological Term Annotations 1.0 null E2F4-21247883-LYMPHOBLASTOID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 17660535-TableS4a GeneSigDB Published Gene Signatures 1.0 null PSMD4 Pathway Commons Protein-Protein Interactions 1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-IS-A3K7-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPJH-0001-SM-3NMDE GTEx Tissue Sample Gene Expression Profiles 1.0 1.35418 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45445 POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Carcinoma HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-TSE9-1226-SM-4DXTM GTEx Tissue Sample Gene Expression Profiles 1.0 0.919115 HDAC1 ENCODE Transcription Factor Targets 1.0 null Ectrodactyly DisGeNET Gene-Disease Associations 1.0 null H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Drug-Related Side Effects and Adverse Reactions CTD Gene-Disease Associations 1.0 1.50953 hepatitis a DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.22865 umbilical cord blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.28107 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEG5-0006-SM-2I5FZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.986073 Breast Cancer_Mammary gland_GSE2528 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.52655 Perturb_3_KO_Cnot6l_SRP152802 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 13.2767 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24878 POLR2AphosphoS5_Panc1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SIX5 ENCODE Transcription Factor Targets 1.0 null abnormal appendicular skeleton morphology HPO Gene-Disease Associations 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF384 ENCODE Transcription Factor Targets 1.0 null AIM2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00611677 Adult_Liver Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.24227 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.09953 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KDM5A ENCODE Transcription Factor Targets 1.0 null SG in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.946266 Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell type benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.217352 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.40052 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.83605 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.98492 ELF1_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-REY6-2126-SM-48FD9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.862711 KDM5B ENCODE Transcription Factor Targets 1.0 null H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUL4B Pathway Commons Protein-Protein Interactions 1.0 null ZKSCAN1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part LOCATE Curated Protein Localization Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.09437 hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.44108 infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.799513 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB-20176806-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BICR16 CCLE Cell Line Gene CNV Profiles 1.0 1.48476 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -1.50256 critically GeneRIF Biological Term Annotations 1.0 null periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62221 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.952635 KARPAS299 CCLE Cell Line Gene Expression Profiles -1.0 -1.74293 TCF12_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A6BB-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL3H-0008-SM-4E3HU GTEx Tissue Sample Gene Expression Profiles 1.0 1.03238 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.897811 GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08223 GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20536 BACH1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909303 NR2F2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DMS 273 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89532 head of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.72645 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.11099 HCC1395 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054309 HSPA8 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30966 MYC_Activation - 21 days_GDS2025_727_mouse_Pancreatic islet beta cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Simple lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17826 NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19415 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFF ENCODE Transcription Factor Targets 1.0 null amygdaloid complex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.84644 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17660535-TableS4b GeneSigDB Published Gene Signatures 1.0 null fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.872142 dorsomedial preoptic area, superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28275 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03573 arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.92766 central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.062446 hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03269 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.444482 POLR2A_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.40758 Stomach Carcinoma DisGeNET Gene-Disease Associations 1.0 null connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.389666 ES8 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 H3K9ac_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HEPG2 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.33803 GTEX-QCQG-0008-SM-48U2G GTEx Tissue Sample Gene Expression Profiles 1.0 0.913248 intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RL7 BioGPS Cell Line Gene Expression Profiles 1.0 0.854462 SMARCB1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null T98G CCLE Cell Line Gene CNV Profiles 1.0 1.67724 particle GeneRIF Biological Term Annotations 1.0 null posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.73931 outer CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59154 liver_c HPA Tissue Sample Gene Expression Profiles 1.0 1.03819 organelle LOCATE Predicted Protein Localization Annotations 1.0 null maintenance GeneRIF Biological Term Annotations 1.0 null H3K79me2_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PX3G-0006-SM-33HBQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11351 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36766 H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RSPO1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00530967 POLR2A_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3157-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 H4K20me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tumour GeneRIF Biological Term Annotations 1.0 null TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2BK5ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cerebellum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02937 JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854125 H3K27ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCIH69 CCLE Cell Line Gene Expression Profiles 1.0 2.11869 lymphnode_5c HPA Tissue Sample Gene Expression Profiles -1.0 -1.29765 H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SBC-1 GDSC Cell Line Gene Expression Profiles 1.0 2.02595 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22349 SNU1105 Achilles Cell Line Gene Essentiality Profiles 1.0 1.09679 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null MDAMB453 CCLE Cell Line Gene CNV Profiles -1.0 -2.26567 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A6HP-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null D283MED CCLE Cell Line Gene CNV Profiles -1.0 -2.1341 chromosomal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.36741 doxorubicin_homo sapiens_gpl6947_gse25741 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67325 chloragogen cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.968523 Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08198 MAPK14_KO_GDS2693_535_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DSS1/SEM1 InterPro Predicted Protein Domain Annotations 1.0 null IGF1R_knockout_151_GSE32936 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.69328 autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042618 RUNX1-22412390-EML-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-0003-SM-3NM8M GTEx Tissue Sample Gene Expression Profiles 1.0 1.21832 GTEX-XUW1-0005-SM-4BOQ7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36645 Cerebellar cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23078 TAL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the middle ear HPO Gene-Disease Associations 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50957 SAC3D1 Pathway Commons Protein-Protein Interactions 1.0 null body wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.243918 GTEX-QLQ7-0005-SM-2S1QP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16698 Diverticular Bleeding DisGeNET Gene-Disease Associations 1.0 null finger syndactyly HPO Gene-Disease Associations 1.0 null Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38827 H3K4me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.80062 Uveal Melanoma DisGeNET Gene-Disease Associations 1.0 null GTEX-X638-0003-SM-47JZ1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05507 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41636 hepatitis b DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.34025 ZFX-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.47806 POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USP7 Pathway Commons Protein-Protein Interactions 1.0 null 19658189-TableS4 GeneSigDB Published Gene Signatures 1.0 null gonadal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.986007 TAF1 ENCODE Transcription Factor Targets 1.0 null Perturb_1800_KO_Hif1a_SRP198677 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.56509 RB1_KD_GSE50532_656_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null thyroid cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.107403 liver TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08334 ventrolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.52305 SNU5 CCLE Cell Line Gene Expression Profiles 1.0 2.24306 EGR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PIK3CA_knockdown_182_GSE46869 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.28477 H3K4me1_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HL60 BioGPS Cell Line Gene Expression Profiles -1.0 -1.06421 SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06501 USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X62O-0005-SM-46MV1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31072 male reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.919916 GTEX-QVUS-0426-SM-48FE3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04922 Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75G-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NOTCH1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00382346 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ES6 GDSC Cell Line Gene Expression Profiles 1.0 1.93782 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null myeloma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.117684 primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045752 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.903158 LIG3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00621497 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOD1 MSigDB Cancer Gene Co-expression Modules 1.0 null H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OHPK-0006-SM-2HMKH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.75968 Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 H3K4me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82439 septal nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.841392 Fatty Liver, Alcoholic CTD Gene-Disease Associations 1.0 1.16203 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05224 dna-directed rna polymerase ii, holoenzyme COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27123 Simple lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22454 CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69274 HCC1143 CCLE Cell Line Gene Expression Profiles -1.0 -2.4169 Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.44961 EVSAT CCLE Cell Line Gene CNV Profiles 1.0 1.65054 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF217_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neurosphere_Cultured_Cells_Cortex_Derived Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.06258 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5294 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.903161 Perturb_5991_KD_ZNF438_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.89796 ZFAND2B Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.45813 GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.58264 POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30423 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.89284 protein complex GO Cellular Component Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7146-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QF-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46581 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00179 Extragonadal Germ Cell Tumor DisGeNET Gene-Disease Associations 1.0 null Perturb_6648_KD_IQGAP2_SRP398102 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 DG-75 GDSC Cell Line Gene Expression Profiles -1.0 -2.50466 immature ovarian follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.324605 Perturb_5223_KO_Tet1/2/3_SRP182030 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 19.2218 DNAJB1 Hub Proteins Protein-Protein Interactions 1.0 null ventral tuberomammillary nucleus, superficial part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24072 BACH1 ENCODE Transcription Factor Targets 1.0 null endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Perturb_11702_KD_MIR31HG_SRP051359 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.6635 NFYB ENCODE Transcription Factor Targets 1.0 null forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Split Foot DisGeNET Gene-Disease Associations 1.0 null diethylstilbestrol_mus musculus_gpl81_gse1839 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CEBPD_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09792 GTEX-RWSA-0005-SM-2XCAO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30165 NELFE ENCODE Transcription Factor Targets 1.0 null H3K36me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXP2_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null follicular fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242054 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.17355 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 nucleus GO Cellular Component Annotations 2023 1.0 null HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.74087 POLR2A_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null structure GeneRIF Biological Term Annotations 1.0 null GTEX-S3XE-0126-SM-4AD4R GTEx Tissue Sample Gene Expression Profiles 1.0 0.867302 Exanthema CTD Gene-Disease Associations 1.0 1.0353 CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_60_KO_Pabpn1l_SRP226170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.8524 FU97 CCLE Cell Line Gene Expression Profiles 1.0 1.41669 Cell Transformation, Neoplastic CTD Gene-Disease Associations 1.0 1.29688 Rectum adenocarcinoma_READ_TCGA-DY-A1DD-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27057 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C1-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25613 GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64262 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null GTEX-XYKS-1526-SM-4BRUP GTEx Tissue Sample Gene Expression Profiles 1.0 0.84009 azoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.709975 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.174881 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null trophoblastic neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.138206 RAD23B MSigDB Cancer Gene Co-expression Modules 1.0 null C32 CCLE Cell Line Gene Expression Profiles 1.0 2.19765 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMD3-0006-SM-4AT5X GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02159 nucleoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 ELF1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null transformed GeneRIF Biological Term Annotations 1.0 null external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.03856 EP300_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.45972 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null myoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.168854 UBQLN1 Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.89532 ZNF384_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RNOR-2326-SM-2TF4I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.850931 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 1.05461 Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TYK2_knockdown_35_GDS4754 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.5618 H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null pancreas_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.1662 Frontal pole, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14924 SIN3A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null trovafloxacin_homo sapiens_gpl96_gse9166 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null RAD21 MSigDB Cancer Gene Co-expression Modules 1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15776 diagnosis GeneRIF Biological Term Annotations 1.0 null superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6445 H3K9ac_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848223 hypogonadism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.900746 Oligodactyly DisGeNET Gene-Disease Associations 1.0 null recombinational GeneRIF Biological Term Annotations 1.0 null Myocardial Infarction_Myocardial tissue_GSE4105 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.69169 Perturb_6712_KD_STAU1_SRP266909 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.3036 MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.50846 anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.226952 estradiol_mus musculus_gpl75_gse280 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null KIAA0368 Pathway Commons Protein-Protein Interactions 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neural Tube Defects CTD Gene-Disease Associations 1.0 1.17202 BRCA1 ENCODE Transcription Factor Targets 1.0 null GTEX-QEG5-1426-SM-447AS GTEx Tissue Sample Gene Expression Profiles 1.0 1.08004 H3K27ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFG8-0006-SM-3GIKS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12368 Perturb_13889_KD_BRCA1_SRP135799 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 5.97606 abnormality of digit HPO Gene-Disease Associations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bonemarrow BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.846055 artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058021 GTEX-XMK1-0226-SM-4B65D GTEx Tissue Sample Gene Expression Profiles 1.0 0.861391 TUBB4B LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00628558 INTS4 Pathway Commons Protein-Protein Interactions 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20986 H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -2.71485 JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05224 ATOX1 MSigDB Cancer Gene Co-expression Modules 1.0 null liver HPA Tissue Gene Expression Profiles 1.0 1.31691 skeletalmuscle_a HPA Tissue Sample Gene Expression Profiles 1.0 0.95822 H3K9ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A562-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.43385 REC1_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE CCLE Cell Line Proteomics 1.0 4.44016 TGFBR1_activemutant_291_GSE14523 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.61224 H4K20me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SETDB1 ENCODE Transcription Factor Targets 1.0 null GTEX-T6MO-0006-SM-32QOU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.26519 dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.875851 KG1 CCLE Cell Line Gene CNV Profiles -1.0 -2.45922 H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MDN1 Pathway Commons Protein-Protein Interactions 1.0 null Neoplasm Metastasis DisGeNET Gene-Phenotype Associations 1.0 null POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARS-ddORF6_60Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.9575 ZFX ChEA Transcription Factor Targets 1.0 null H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OIZG-0008-SM-4E3J2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71325 537 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.25514 primary motor cortex (area M1, area 4)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33855 GTEX-W5X1-0001-SM-3P61V GTEx Tissue Sample Gene Expression Profiles 1.0 3.0667 emboliform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06716 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49651 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.88609 COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.85815 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null functional abnormality of the inner ear HPO Gene-Disease Associations 1.0 null GTEX-RVPV-0008-SM-47JYW GTEx Tissue Sample Gene Expression Profiles 1.0 1.04435 H3K4me3_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TP53-23651856-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_8695_KO_Stat1_SRP364338 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Kidney Failure, Chronic HuGE Navigator Gene-Phenotype Associations 1.0 null intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null CCND1-20090754-RETINA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEL GDSC Cell Line Gene Expression Profiles -1.0 -1.97453 H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FXR MotifMap Predicted Transcription Factor Targets 1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null PRC_DEPLETION_GDS3532_96_human_U2OS cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.948095 DAP MSigDB Cancer Gene Co-expression Modules 1.0 null POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null migraine without aura DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.235616 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.832081 ETS1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PECAPJ15 CCLE Cell Line Gene CNV Profiles 1.0 1.50874 GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.12357 primary auditory cortex (core)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08905 specific GeneRIF Biological Term Annotations 1.0 null CBX3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBTF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT1 ENCODE Transcription Factor Targets 1.0 null MYC_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MBD4_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-0006-SM-3MJF6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.990896 CLPP_KO_GDS4791_541_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null ATF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK ENCODE Transcription Factor Targets 1.0 null r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01194 male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.568386 H3K4me3_G1E_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the skeletal system HPO Gene-Disease Associations 1.0 null C32TG Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28862 internal female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.746689 outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26874 vein disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.112596 Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2118 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.04937 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.851866 Lung squamous cell carcinoma_LUSC_TCGA-85-A5B5-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.916251 Heart Defects, Congenital CTD Gene-Disease Associations 1.0 1.02262 Perturb_4166_KO_Bcl11a_SRP334609 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.5097 Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RMUGS CCLE Cell Line Gene CNV Profiles -1.0 -1.54113 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.30013 HAT1 MSigDB Cancer Gene Co-expression Modules 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23722 GTEX-X4EP-0011-R2B-SM-3P625 GTEx Tissue Sample Gene Expression Profiles 1.0 0.860371 GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24235 17616640-TableS1 GeneSigDB Published Gene Signatures 1.0 null hippocampus (hippocampal formation)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22738 ovary GTEx Tissue Gene Expression Profiles 1.0 1.21038 GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03745 u698 HPA Cell Line Gene Expression Profiles 1.0 1.41318 PSMC5 Pathway Commons Protein-Protein Interactions 1.0 null PDX1 JASPAR Predicted Transcription Factor Targets 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.864427 tetracycline-2080 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5169-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-N7MS-0007-SM-2D7W1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4288 SREBP2-21459322-LIVER-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.46255 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06798 external male genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.095412 19204204-SupplementaryTable5 GeneSigDB Published Gene Signatures 1.0 null NCIH1581 CCLE Cell Line Gene Expression Profiles 1.0 1.41396 Adenoma, Liver Cell CTD Gene-Disease Associations 1.0 1.26886 POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null estradiol_homo sapiens_gpl96_gds2324 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05158 Perturb_17720_KO_Apoe/Ahcy_SRP342341 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.7314 Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4987 ventrolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03508 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.09006 Perturb_9457_OE_Rnaseh1_SRP182028 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.45384 NCI-H1048 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.45954 substrate GeneRIF Biological Term Annotations 1.0 null GDF15 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.006257 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53242 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.972665 INTS7 Pathway Commons Protein-Protein Interactions 1.0 null MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUX1 ENCODE Transcription Factor Targets 1.0 null cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.213621 H3K4me1_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OVSAHO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.989516 intracellular part LOCATE Curated Protein Localization Annotations 1.0 null EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.13564 GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63949 intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-YL-A8HM-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Spinal Cord Injury_CNS - Spinal Cord (MMHCC)_GSE16710 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -3.01414 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14492 STAT5A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18731 JJ012 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.840973 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1806_BREAST CCLE Cell Line Proteomics 1.0 8.44172 INTS5 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QDT8-2526-SM-48TYX GTEx Tissue Sample Gene Expression Profiles 1.0 0.874018 r6 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0131 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18589 H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_5899_KD_CHAF1A_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.27928 GTEX-W5WG-0002-SM-3NMDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.5451 PSMA6 Pathway Commons Protein-Protein Interactions 1.0 null Claw Hand DisGeNET Gene-Disease Associations 1.0 null carcinoma, squamous cell; skin neoplasms; squamous cell carcinoma GAD Gene-Disease Associations 1.0 null H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.86822 Non-alcoholic Fatty Liver Disease CTD Gene-Disease Associations 1.0 1.26886 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.48378 Lung squamous cell carcinoma_LUSC_TCGA-39-5027-01A-21R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.42241 Perturb_6412_KO_TP53_SRP274402 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.22357 BRD-A38030642_cyclosporin A_HCC515_24.0_h_10.0_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Breast Neoplasms, Male HuGE Navigator Gene-Phenotype Associations 1.0 null epididymis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.148446 HCFC1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRK-0126-SM-3NB1E GTEx Tissue Sample Gene Expression Profiles 1.0 1.05484 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP38 Pathway Commons Protein-Protein Interactions 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARID3A ENCODE Transcription Factor Targets 1.0 null SLR20 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.14285 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01623 Meningioma HuGE Navigator Gene-Phenotype Associations 1.0 null embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.315861 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.15598 response to stimulus GO Biological Process Annotations 2015 1.0 null doxycycline_homo sapiens_gpl570_gse21912 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HOP-92 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835245 Perturb_10892_KO_Eif6_ERP121455 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.72241 H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the globe HPO Gene-Disease Associations 1.0 null H3K9ac_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KG1 CCLE Cell Line Gene Expression Profiles -1.0 -1.46629 r3 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84209 HS 255.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.81475 MXI1 ENCODE Transcription Factor Targets 1.0 null THAP11-20581084-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null gastrointestinal tract TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5EA-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48084 Lung adenocarcinoma_LUAD_TCGA-49-6767-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYBL2 ENCODE Transcription Factor Targets 1.0 null HCC2218 CCLE Cell Line Gene CNV Profiles -1.0 -2.12571 fat_8b HPA Tissue Sample Gene Expression Profiles -1.0 -0.90237 neck TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.41169 FOSL1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null goiter DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.743547 H3K27ac_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNU466 CCLE Cell Line Gene CNV Profiles 1.0 1.49391 graves' disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.246799 VDR-33458620-PRIMARYEPITHELIAL-HUMAN-PROSTATE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66693 rpn3s3 GeneRIF Biological Term Annotations 1.0 null TAF1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QV44-1926-SM-2S1RF GTEx Tissue Sample Gene Expression Profiles 1.0 1.50841 Perturb_734_KD_SETD1A_SRP293637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.38794 brain neoplasms; glioma GAD Gene-Disease Associations 1.0 null KAT2A_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL4W-0008-SM-4E3I2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.4425 intracellular organelle lumen COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 responsible GeneRIF Biological Term Annotations 1.0 null Declive (VI), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40614 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PRECLH CCLE Cell Line Gene Expression Profiles -1.0 -1.85919 POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null UFD1L Pathway Commons Protein-Protein Interactions 1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TT-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.937854 GTEX-P4QT-2426-SM-3NMCL GTEx Tissue Sample Gene Expression Profiles 1.0 1.06481 GTEX-QCQG-1326-SM-48U24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.28831 HCC1187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.098 HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74829 chronic fatigue syndrome GWASdb SNP-Disease Associations 1.0 0.510061 GTEX-XV7Q-0005-SM-4BRWI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95386 Adrenocortical carcinoma_ACC_TCGA-OR-A5LM-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 MXI1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell culture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236627 Perturb_13101_OE_Dux_SRP220068 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.54037 primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.79359 U-2-OS GDSC Cell Line Gene Expression Profiles 1.0 1.63021 SPI1 ChEA Transcription Factor Targets 1.0 null proteasome core complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.276304 ATF2_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior olivary complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.833734 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.17748 HCC2814 CCLE Cell Line Gene Expression Profiles 1.0 1.74114 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04572 LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XMK1-0001-SM-4B64F GTEx Tissue Sample Gene Expression Profiles 1.0 1.69565 abnormality of the anterior segment of the eye HPO Gene-Disease Associations 1.0 null Perturb_3795_KO_Rnf40_ERP123195 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.63676 STAT3 ENCODE Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-0002-SM-3NMDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.33049 E2F6 ENCODE Transcription Factor Targets 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 2.03623 H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.01018 r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54392 INTS6 Pathway Commons Protein-Protein Interactions 1.0 null POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Folic Acid CTD Gene-Chemical Interactions 1.0 null SK-MEL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.01455 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.67313 MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tcof1_15522210_neuroblastoma_gof_mouse_gpl339_gds998 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.591381 GTEX-W5X1-2526-SM-3GILC GTEx Tissue Sample Gene Expression Profiles 1.0 0.998619 TCF12_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-0004-SM-46MWA GTEx Tissue Sample Gene Expression Profiles 1.0 0.847498 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.3229 GTEX-WHPG-0004-SM-3NMDO GTEx Tissue Sample Gene Expression Profiles 1.0 1.10796 dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33893 POLR2B Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMB1 Pathway Commons Protein-Protein Interactions 1.0 null CREB1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF384_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null prostate_a HPA Tissue Sample Gene Expression Profiles 1.0 0.933025 HS746T COSMIC Cell Line Gene CNV Profiles 1.0 2.283 GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles 1.0 0.927049 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -2.156 arsenic trioxide_homo sapiens_gpl201_gse48441 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null thyroid gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.38385 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SUCS-0008-SM-4DM53 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0491 NCIH1355_LUNG CCLE Cell Line Proteomics 1.0 3.63127 hsa-miR-3657 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 VIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09372 GTEX-T2YK-0005-SM-32QOV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.857574 lateral septal nucleus, intermedio-intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49047 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.937865 GTEX-QXCU-0008-SM-48FCH GTEx Tissue Sample Gene Expression Profiles 1.0 0.866761 MAFK_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85766 Perturb_733_KD_PTBP3_SRP293637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.39131 KNS-62 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.44093 SET2 CCLE Cell Line Gene CNV Profiles -1.0 -1.79584 UBTF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Accessory facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11323 inner CP in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63763 KIT_activemutant_55_GSE17743 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.50191 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23003 Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.058164 PML ENCODE Transcription Factor Targets 1.0 null limb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.928906 GTEX-WH7G-0002-SM-4LVN9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.887414 SK-N-FI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.12924 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0103 ZNF217 ENCODE Transcription Factor Targets 1.0 null ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GTEX-NFK9-1726-SM-3TW8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.71268 bone BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.60952 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ranolazine_mus musculus_gpl1261_gse25767 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13796 posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06589 Perturb_3796_OE_Nrf2_SRP057556 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.73458 NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26961 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.50546 nephron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07406 H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XX-0626-SM-3NMC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.862967 POLR2A_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TLN2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null fasciola cinerea Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.55007 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.07353 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925358 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MO-0008-SM-4DM6T GTEx Tissue Sample Gene Expression Profiles 1.0 0.850145 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61697 H3ac_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11551 blood GTEx Tissue Gene Expression Profiles -1.0 -1.55803 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28582 GTEX-X585-0002-SM-46MVA GTEx Tissue Sample Gene Expression Profiles 1.0 1.1721 IV, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32624 auditory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.258064 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06439 controls GeneRIF Biological Term Annotations 1.0 null BCL6-25482012-CML-JURL-MK1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ASPC1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.12224 umbilical artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.138545 Perturb_5911_KD_GATAD2B_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.00276 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95324 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.983983 aplasia/hypoplasia involving bones of the upper limbs HPO Gene-Disease Associations 1.0 null Crus 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86088 p63 GeneRIF Biological Term Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ7-0008-SM-4E3JS GTEx Tissue Sample Gene Expression Profiles 1.0 1.14141 H3K4me2_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.23411 SARS-CoV_60Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.12941 PSMD9 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_11975_KO_Star_SRP302975 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.0964 EBF1 ENCODE Transcription Factor Targets 1.0 null OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.71683 EGR-1_KO_GDS3607_526_mouse_Retina - 42 Days (POST-NATAL) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null MAX_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATM_knockout_16_GDS1544 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.32189 PRKAR1A MSigDB Cancer Gene Co-expression Modules 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.36289 SQ1_LUNG CCLE Cell Line Proteomics 1.0 2.65145 BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EP300_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A53L-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3im GeneRIF Biological Term Annotations 1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SUCS-0002-SM-3NMAJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.15238 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82155 Choline CTD Gene-Chemical Interactions 1.0 null ZEB1 ENCODE Transcription Factor Targets 1.0 null POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MEF2A-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null penis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.224645 H3K4me1_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CR-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.11668 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.55847 HEL CCLE Cell Line Gene Expression Profiles -1.0 -1.65619 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.82635 MAFK_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.972917 outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.943665 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null female reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.909666 OVCAR4 BioGPS Cell Line Gene Expression Profiles 1.0 1.45204 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null placenta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072291 cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.251015 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053006 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61064 ASPC-1 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TMMY-1126-SM-4DXSX GTEx Tissue Sample Gene Expression Profiles 1.0 1.18725 GTEX-UJMC-0008-SM-4IHKK GTEx Tissue Sample Gene Expression Profiles 1.0 0.883189 SPSB1 Hub Proteins Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7247-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.57674 TRIM24_knockout_298_GDS3087 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.42401 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.18771 POLR2A_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecule GeneRIF Biological Term Annotations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone development disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.774114 NCI-H23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.01018 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.07568 GTEX-Q2AG-0005-SM-33HBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01388 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.99334 GTEX-P4PQ-0005-SM-2HMKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.2079 SCC25_UPPER_AERODIGESTIVE_TRACT CCLE Cell Line Proteomics 1.0 4.04619 NRF2-20460467-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null meconium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.261284 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.866646 caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.869663 HN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.32928 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.46919 Osteoporosis HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-XGQ4-0008-SM-4AT3Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.12147 ADSS2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00487509 H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null intermediate stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10192 hypogonadotropism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.517265 HEY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14186 SNUC1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.6715 H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null locus GeneRIF Biological Term Annotations 1.0 null traffic GeneRIF Biological Term Annotations 1.0 null H3K79me2_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TRIM28_U2OS_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.536957 COV434 CCLE Cell Line Gene Expression Profiles -1.0 -1.85871 GTEX-WFG7-0001-SM-3P61S GTEx Tissue Sample Gene Expression Profiles 1.0 2.5257 H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.34078 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.934137 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36318 primary auditory cortex (core)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.50393 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FBXO7 Pathway Commons Protein-Protein Interactions 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.13941 EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.8797 juvenile TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.525166 peroxisome LOCATE Predicted Protein Localization Annotations 1.0 null cervical GeneRIF Biological Term Annotations 1.0 null GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.981432 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.15211 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.70351 Perturb_5795_KO_Stat3_ERP105170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.9208 HDAC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25801 Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044852 GTEX-UJMC-0226-SM-4IHLH GTEx Tissue Sample Gene Expression Profiles 1.0 0.826803 NCIH1339 CCLE Cell Line Gene CNV Profiles -1.0 -1.57465 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHESOAD1 CCLE Cell Line Gene CNV Profiles -1.0 -1.35263 Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Micronuclei, Chromosome-Defective CTD Gene-Disease Associations 1.0 1.20262 endocrine organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.219057 NCI-SNU-5 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 GTEX-OXRN-0005-SM-2I5EU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21098 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08294 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null microbody LOCATE Predicted Protein Localization Annotations 1.0 null parataenial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.969003 GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57034 TAF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WK11-0006-SM-3NB3J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07685 Atrophy CTD Gene-Disease Associations 1.0 1.18193 16141321-Table2 GeneSigDB Published Gene Signatures 1.0 null NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.37611 double-strand break repair GO Biological Process Annotations 2023 1.0 null KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.34508 H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AML - Acute myeloid leukemia_Mononuclear Leukocyte_GSE2191 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 0.194705 H3K27ac_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.45612 HUWE1 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-7499-01A-11R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17038 central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null dorsolateral prefrontal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.937865 viral infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.07236 H3K36me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-0001-SM-3NMAK GTEx Tissue Sample Gene Expression Profiles 1.0 0.891926 intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053772 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30611 Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62813 endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.282225 STAT5A ENCODE Transcription Factor Targets 1.0 null Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -2.58467 dorsolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.960691 TEAD4 ENCODE Transcription Factor Targets 1.0 null Perturb_5894_KD_CBX5_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.41961 Heart Diseases CTD Gene-Disease Associations 1.0 1.29348 PSMD2 Pathway Commons Protein-Protein Interactions 1.0 null MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.19268 nucleus COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 RPN1 Hub Proteins Protein-Protein Interactions 1.0 null H3K4me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null chloragocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01681 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76442 Brain Lower Grade Glioma_LGG_TCGA-FG-A711-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25535 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null TE159T CCLE Cell Line Gene Expression Profiles -1.0 -2.20414 nucleus GeneRIF Biological Term Annotations 1.0 null H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null SIX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03541 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05571 NFIC ENCODE Transcription Factor Targets 1.0 null EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44842 HS751T CCLE Cell Line Gene Expression Profiles -1.0 -1.555 HPAF-II Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26961 Inflammation CTD Gene-Disease Associations 1.0 1.47322 foot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.151992 WDR63 Pathway Commons Protein-Protein Interactions 1.0 null A-VN-1203-2004(H5N1)_Day1-10^3pfu_22074594_GSE33263 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.51336 aplasia/hypoplasia of the extremities HPO Gene-Disease Associations 1.0 null r3 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64971 GTEX-N7MS-0008-SM-4E3JI GTEx Tissue Sample Gene Expression Profiles 1.0 1.10031 GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09933 ovarian benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.417644 Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHOC5 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.30624 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82439 AHR LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00497163 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.29375 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thyroid cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.120005 thyroid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.47896 ELF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6097_KD_ZNF438_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0114 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFJO-0002-SM-3P61X GTEx Tissue Sample Gene Expression Profiles 1.0 1.48173 SPIB JASPAR Predicted Transcription Factor Targets 1.0 null H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11897 GTEX-O5YW-0006-SM-3LK6E GTEx Tissue Sample Gene Expression Profiles -1.0 -2.6466 H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF143_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS746T CCLE Cell Line Gene Expression Profiles 1.0 2.88726 sensorineural hearing loss DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.268332 JUND_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LENG8 Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.940163 20460173-ImmPortAntigenProcessingandPresentation GeneSigDB Published Gene Signatures 1.0 null GTEX-TML8-0001-SM-3NMAF GTEx Tissue Sample Gene Expression Profiles 1.0 1.44108 Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.41813 mcf7 HPA Cell Line Gene Expression Profiles 1.0 1.37873 pituitary adenoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.380739 Perturb_2190_KD_ETS2_SRP083762 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.96563 proteasome complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null cellular response to stimulus GO Biological Process Annotations 2015 1.0 null amygdaloid complex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.80366 EBC1 CCLE Cell Line Gene Expression Profiles 1.0 1.44648 TAF1_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null V Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.954989 REST_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07522 Hypospadias CTD Gene-Disease Associations 1.0 1.15256 KLF4-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.9144 GTEX-W5X1-0006-SM-3GIJZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03297 Cervix Carcinoma DisGeNET Gene-Disease Associations 1.0 null REST_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.914688 Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null XRCC5 MSigDB Cancer Gene Co-expression Modules 1.0 null SKOV3 CCLE Cell Line Gene CNV Profiles -1.0 -1.6737 HS255T CCLE Cell Line Gene Expression Profiles -1.0 -1.93679 CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.102921 CEBPD ENCODE Transcription Factor Targets 1.0 null MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31415 CLPB Hub Proteins Protein-Protein Interactions 1.0 null MYC_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Split hand foot deformity 1 CTD Gene-Disease Associations 1.0 2.88009 pituitary gland disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.486266 Perturb_4298_KD_BCL9_SRP242206 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 6.15327 POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.80194 UACC-812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.968024 OPM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.50772 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lumbar spine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31332 SIX5_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSME4 Pathway Commons Protein-Protein Interactions 1.0 null hypothalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 breast cancer GAD Gene-Disease Associations 1.0 null SP1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFG8-0001-SM-4LVN8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30195 POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.896949 Type 1 diabetes mellitus_Muscle - Striated (Skeletal) (MMHCC)_GSE1659 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.69278 GTEX-W5WG-1126-SM-4LMK4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0241 GPR141 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0064336 diethylstilbestrol_mus musculus_gpl6887_gse37969 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Developmental Delay (Disorder) DisGeNET Gene-Phenotype Associations 1.0 null Perturb_5971_KD_TAF15_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -8.54208 Prostate Carcinoma DisGeNET Gene-Disease Associations 1.0 null emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.882663 posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03514 CREB1-23762244-HIPPOCAMPUS-RAT ChEA Transcription Factor Targets 2022 1.0 null ELF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null renal tubule epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.535042 HT55 GDSC Cell Line Gene Expression Profiles 1.0 1.97573 Carcinogenesis DisGeNET Gene-Phenotype Associations 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.52533 H3K4me3_NB4_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBL4A Pathway Commons Protein-Protein Interactions 1.0 null FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null eGFP-GATA2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JARID1A-20064375-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_9913_KD_HNRNPK_SRP013565 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.81946 H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RBBP5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.825021 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Perturb_15439_KD_NUSAP1_SRP074246 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.2228 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03054 TBL1XR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_6674_KD_HDAC9_SRP159451 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.81074 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88078 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57496 CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null embryo TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Perturb_11936_KD_SMARCD1_ERP132117 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.45163 UBR1 Pathway Commons Protein-Protein Interactions 1.0 null ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.924745 ATF1 ENCODE Transcription Factor Targets 1.0 null macromolecular complex GO Cellular Component Annotations 2015 1.0 null GTEX-S32W-0126-SM-4AD61 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32481 hippocampus (hippocampal formation)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.968093 Nausea CTD Gene-Disease Associations 1.0 1.07447 Acute pancreatitis_Pancreas_GSE3644 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.40579 SCC4 CCLE Cell Line Gene Expression Profiles 1.0 1.42835 GTF2F1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RB1_KD_GSE50532_657_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null STAT3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-MB-A5Y9-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pyramus (VIII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17449 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.59167 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GM2345 BioGPS Cell Line Gene Expression Profiles 1.0 1.224 KDM5A ChEA Transcription Factor Targets 1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPK5-0006-SM-3GAD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63163 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.91373 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.973801 GTEX-X3Y1-0006-SM-3P5ZG GTEx Tissue Sample Gene Expression Profiles -1.0 -2.02262 SK-MEL-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.20087 spinal cord disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.223165 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UCHL5 Pathway Commons Protein-Protein Interactions 1.0 null SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CALU3 CCLE Cell Line Gene Expression Profiles -1.0 -1.65173 MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X15G-0005-SM-3NMDA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16401 CEBPB_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_2823_KD_MEG3_SRP238079 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Supratrigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12768 abnormality of limb bone morphology HPO Gene-Disease Associations 1.0 null JAK2_activemutant_72_GSE21842 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.90897 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.841339 DDX39B Pathway Commons Protein-Protein Interactions 1.0 null inner CP in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18291 UBQLN4 Pathway Commons Protein-Protein Interactions 1.0 null corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09839 REST_PFSK-1_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null gonad TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.820666 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null liver TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-XPVG-2026-SM-4B65E GTEx Tissue Sample Gene Expression Profiles 1.0 0.833019 MCF7_BREAST CCLE Cell Line Proteomics 1.0 2.01424 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.839601 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.864871 vagina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.682287 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Perturb_12540_KO|OE_FBXO11|FBXO11_SRP278534 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05248 RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null C32 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HEYA8 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.5374 r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83196 11823860-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null MAX_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVCAR4 CCLE Cell Line Gene CNV Profiles 1.0 1.46691 HCC2218 CCLE Cell Line Gene Expression Profiles -1.0 -1.47758 Perturb_951_KO_Suz12_SRP322809 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -10.2814 NCI-H510A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0103 BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CUL2 Pathway Commons Protein-Protein Interactions 1.0 null HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null EIF3A Pathway Commons Protein-Protein Interactions 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A3LQ-01A-21R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.71489 SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.45589 Ebolavirus(ZEBOV)_1hr_Macrophage_22028943_GSE31747 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.57345 NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.26447 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.45639 GTEX-WZTO-0006-SM-3NM9T GTEx Tissue Sample Gene Expression Profiles -1.0 -2.01004 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null H3K56ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.842986 GTEX-QCQG-1226-SM-48U23 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06705 CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Folium-tuber vermis (VII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18051 16207381-Table1Sa GeneSigDB Published Gene Signatures 1.0 null GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17268 E2F1-20622854-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-NL3G-0008-SM-4E3JX GTEx Tissue Sample Gene Expression Profiles 1.0 1.66639 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null organic cyclic compound metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-P78B-1026-SM-3NMC4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.846293 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.26603 GABPA_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33519 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TYK2_knockdown_176_GSE44652 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 2.56181 Ovarian Neoplasm DisGeNET Gene-Disease Associations 1.0 null supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01335 GTEX-Q2AG-0008-SM-48U2K GTEx Tissue Sample Gene Expression Profiles 1.0 1.71432 Urinary Bladder Neoplasms CTD Gene-Disease Associations 1.0 1.5138 immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 GTF3C2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1 ENCODE Transcription Factor Targets 1.0 null AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.11905 Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.55863 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.168 digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4624 FOS_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ATP1B3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00559359 model GeneRIF Biological Term Annotations 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.85475 MAP4K1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00461467 MYBL2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null Seminoma DisGeNET Gene-Disease Associations 1.0 null Fever CTD Gene-Disease Associations 1.0 1.02933 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null varicose veins DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.138926 znf148_21828133_erythroblast_lof_human_gpl571_gse31092 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.145256 H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898989 r2 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35269 MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.91261 Lung squamous cell carcinoma_LUSC_TCGA-94-A5I4-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ovary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.721988 H3K4me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Adenocarcinoma HuGE Navigator Gene-Phenotype Associations 1.0 null EVI1-22308434-SKOV3-HUMAN-OVARY-OVARIANCANCER ChEA Transcription Factor Targets 2022 1.0 null Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08198 ZNF274_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null vitamin c_mus musculus_gpl1261_gse37676 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Main olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05515 zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.084074 intermediate stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01662 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.90361 GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30969 attention deficit hyperactivity disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 GTEX-VJYA-0001-SM-3NMDJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.11271 superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22775 POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD2 ENCODE Transcription Factor Targets 1.0 null MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.39617 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null sexual dysfunction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.319726 fin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.249653 GTEX-OHPM-0008-SM-4E3IP GTEx Tissue Sample Gene Expression Profiles 1.0 0.935502 oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.630314 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H1_Cell_Line Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.952966 SPTAN1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00442022 superficial stratum of PO1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28275 CLPP_KO_GSE40207_399_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-R55E-0008-SM-48FCG GTEx Tissue Sample Gene Expression Profiles 1.0 1.06123 MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the upper limb HPO Gene-Disease Associations 1.0 null Perturb_5976_KD_TRA2B_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.18443 20460173-ImmPortComprehensiveListofImmune-RelatedGenes GeneSigDB Published Gene Signatures 1.0 null H2AFZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null monastrol-614 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null posteroventral (inferior) parietal cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1402 transferase complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.002705 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.986766 TNFSF8 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00587812 u138mg HPA Cell Line Gene Expression Profiles -1.0 -0.883907 POLR2A_myocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC202 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.575661 OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49504 SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.33523 UBTF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PTHrP_KD_GDS1664_71_human_MDA-MB-231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null TAGAP LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00567843 GTEX-TKQ1-0003-SM-3NMAE GTEx Tissue Sample Gene Expression Profiles 1.0 1.29418 Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.62397 CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-52-7812-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMD1-0008-SM-4AT41 GTEx Tissue Sample Gene Expression Profiles 1.0 0.9969 integrator complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 altered GeneRIF Biological Term Annotations 1.0 null A361 BioGPS Cell Line Gene Expression Profiles 1.0 1.17595 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21572 Carcinoma, Ovarian Epithelial DisGeNET Gene-Disease Associations 1.0 null SET2 CCLE Cell Line Gene Expression Profiles -1.0 -2.33254 NSFL1C Pathway Commons Protein-Protein Interactions 1.0 null orbital frontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42833 H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null Crus 1, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89611 proteasome complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.163641 interact GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.38584 DDX42 Pathway Commons Protein-Protein Interactions 1.0 null TCF7L2_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01506 CBX3 ENCODE Transcription Factor Targets 1.0 null Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Folium-tuber vermis (VII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16658 polyubiquitinated GeneRIF Biological Term Annotations 1.0 null DNAH6 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26961 H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.90137 GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01084 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MO-0003-SM-3NMAG GTEx Tissue Sample Gene Expression Profiles 1.0 1.97253 GTEX-XK95-0008-SM-4AT5G GTEx Tissue Sample Gene Expression Profiles 1.0 1.05142 HECTD1 Pathway Commons Protein-Protein Interactions 1.0 null EBC1 CCLE Cell Line Gene CNV Profiles 1.0 2.00956 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.267622 GTEX-POMQ-0006-SM-33HBY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23693 ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS944T Achilles Cell Line Gene Essentiality Profiles -1.0 -1.29996 ETS1-20019798-JURKAT-HUMAN ChEA Transcription Factor Targets 2022 1.0 null amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.03781 ELF1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null blastomere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.087879 caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.843687 Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.65954 H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostatic Neoplasms CTD Gene-Disease Associations 1.0 1.09471 H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09931 connective tissue disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.008825 NCIH1568 CCLE Cell Line Gene Expression Profiles 1.0 1.40924 hyperthyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.19532 MLMA COSMIC Cell Line Gene CNV Profiles 1.0 2.283 RNF126 Pathway Commons Protein-Protein Interactions 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null Perturb_6381_KD_POU2AF1_SRP336261 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.36007 dorsolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.838952 CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMC4 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A731-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU466 CCLE Cell Line Gene Expression Profiles 1.0 1.46649 H3K9ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H596 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.24287 SARS-CoV_96Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.86298 GTEX-P4PP-0008-SM-48TDV GTEx Tissue Sample Gene Expression Profiles 1.0 1.11868 H3K4me2_myocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null panhypopituitarism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.196779 Methionine CTD Gene-Chemical Interactions 1.0 null p53 GeneRIF Biological Term Annotations 1.0 null H3K9ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null sensory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043915 TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.229888 adrenal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.366007 Perturb_17610_OE_U2AF35_SRP116787 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.94213 isthmic liminal reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26705 HCC2911 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.8924 adipose tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Hepatomegaly CTD Gene-Disease Associations 1.0 1.42777 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SP2_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null teratoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.081924 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRRC2C Pathway Commons Protein-Protein Interactions 1.0 null CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null Acute Kidney Injury CTD Gene-Disease Associations 1.0 1.03308 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Congenital Absence Of Hand DisGeNET Gene-Disease Associations 1.0 null cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17075 isthmic vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67723 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14076 outer CP in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.993773 U343 CCLE Cell Line Gene Expression Profiles 1.0 2.2028 H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EKLF-21900194-ERYTHROCYTE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null striatum_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.81574 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.19392 MIR140_Silencing_GDS3462_574_mouse_C3H10T1/2 fibroblast cell line GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null LAMA84 CCLE Cell Line Gene CNV Profiles -1.0 -1.38411 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05451 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05781 SP2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Seizures CTD Gene-Disease Associations 1.0 1.03456 lateral parabrachial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30299 GTEX-R53T-0426-SM-48FEM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.887588 Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.26421 KAT2A ENCODE Transcription Factor Targets 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.0534 Perturb_6414_KO_TP53_SRP274402 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.52859 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.989969 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.59165 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.82816 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null PSMC2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GABPA_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4512-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6ES-01A-12R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP14 Pathway Commons Protein-Protein Interactions 1.0 null HCC95_LUNG CCLE Cell Line Proteomics 1.0 2.41004 POLR2A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SIN3A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.5621 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.32829 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.876769 GABP-19822575-HEPG2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null klf4_17017123_rko_gof_human_gpl96_gds1942 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.092806 E2F4_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null survival GeneRIF Biological Term Annotations 1.0 null HS746T CCLE Cell Line Gene CNV Profiles 1.0 2.79938 H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45899 GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08576 granulosa cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.32497 NCI-H1568 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.05622 Skin Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09076 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CA4 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.890416 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.66747 GTEX-XPT6-2026-SM-4B64V GTEx Tissue Sample Gene Expression Profiles 1.0 1.13893 hsa-miR-3152-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43699 VCP Pathway Commons Protein-Protein Interactions 1.0 null YY1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neoplasms CTD Gene-Disease Associations 1.0 1.24997 temporal muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1349 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHOS2 CCLE Cell Line Gene CNV Profiles -1.0 -1.86053 mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22968 GTEX-T6MN-0002-SM-3NMAH GTEx Tissue Sample Gene Expression Profiles 1.0 1.20012 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22775 intermediate part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0341 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.898536 GTEX-O5YU-0008-SM-4E3I7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830595 GTEX-WXYG-0005-SM-3NB3M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.54609 extracellular region part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.217861 H2BK12ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null linkage GeneRIF Biological Term Annotations 1.0 null BRD-K12184916_NVP-BEZ235_MCF10A_3_h_3.33_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51939 Huntington's Disease_Brain_GSE3621 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.9323 gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.126564 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05158 thyrotoxicosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.339806 dorsolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.906504 GTEX-U3ZN-0002-SM-3NMDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.41385 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04435 GABPA_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.00291 MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.831393 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.60102 DDX21 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0042424 temporotympanic muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00723 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBFD1 Pathway Commons Protein-Protein Interactions 1.0 null BRD-K21680192_mitoxantrone_HT29_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null IL6 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00500219 786O CCLE Cell Line Gene Expression Profiles 1.0 1.73761 H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.067654 17616640-TableS3 GeneSigDB Published Gene Signatures 1.0 null Perturb_5979_KD_WDR46_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.47092 GTEX-OXRO-0011-R10A-SM-2I5EH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875678 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.03963 seminiferous tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.216325 gallbladder HPA Tissue Gene Expression Profiles -1.0 -0.883472 POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_5994_KD_ZNF622_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -12.1177 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.829823 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Pancreatic adenocarcinoma_PAAD_TCGA-PZ-A5RE-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17968 Perturb_11704_KD_MIR31HG_SRP051359 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.3972 abnormality of limbs HPO Gene-Disease Associations 1.0 null GTEX-Q2AH-0126-SM-48U2B GTEx Tissue Sample Gene Expression Profiles 1.0 0.972628 CDK13 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00581473 musculoskeletal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.842276 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39V-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal eye morphology HPO Gene-Disease Associations 1.0 null TRIM28-19339689-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular response to stress GO Biological Process Annotations 2015 1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22529 GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00507 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20684 RCOR1 ENCODE Transcription Factor Targets 1.0 null aplasia/hypoplasia involving bones of the hand HPO Gene-Disease Associations 1.0 null CA3 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.857785 vitamin c_homo sapiens_gpl570_gds3635 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null SNU-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72747 TOP1 Pathway Commons Protein-Protein Interactions 1.0 null Weight Loss CTD Gene-Disease Associations 1.0 1.12906 UBE3B Pathway Commons Protein-Protein Interactions 1.0 null VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22937 thyroid gland HPA Tissue Gene Expression Profiles -1.0 -0.90729 H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RAB6A MSigDB Cancer Gene Co-expression Modules 1.0 null TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null early GeneRIF Biological Term Annotations 1.0 null Perturb_1713_KO_Cxcr4_SRP217256 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.95787 superficial stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25478 TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MXI1_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHWD-0005-SM-3LK7D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.8653 cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1143 CCLE Cell Line Gene CNV Profiles -1.0 -1.52892 TAL1 ENCODE Transcription Factor Targets 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.955071 HCC461 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.968024 FOXM1 ENCODE Transcription Factor Targets 1.0 null polycythemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.138941 HNF4A-19761587-HUMAN INTESTINAL CELL LINE CACO-2-human ChEA Transcription Factor Binding Site Profiles 1.0 null gynecomastia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.622575 supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0737 GTEX-S4Q7-0008-SM-3NM8A GTEx Tissue Sample Gene Expression Profiles 1.0 0.981285 Perturb_11912_KD_Arntl2_SRP063609 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.30573 SAP30 ENCODE Transcription Factor Targets 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 LTBR_INHIBITION - 35 Day_GDS2004_737_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAGE_knockout_268_GDS3755 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.53156 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD2_01_351 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.65586 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.925358 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.03071 MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null approximately GeneRIF Biological Term Annotations 1.0 null GB1_CENTRAL_NERVOUS_SYSTEM CCLE Cell Line Proteomics 1.0 3.94847 HAPLN3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00583813 parvocellular part of r8LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21494 GTEX-RUSQ-0226-SM-47JWT GTEx Tissue Sample Gene Expression Profiles 1.0 1.2204 SP2 ENCODE Transcription Factor Targets 1.0 null SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.7509 TAF2 Pathway Commons Protein-Protein Interactions 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SSA3-0005-SM-32QOT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30332 Syndactyly DisGeNET Gene-Disease Associations 1.0 null olfactory bulb, principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04896 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052452 BCPAP CCLE Cell Line Gene CNV Profiles -1.0 -1.42815 GTEX-X4EO-0006-SM-3P5ZF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15019 blastula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.285316 H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null VIIIA Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12998 dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33893 microcephaly DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.215314 polycystic ovary syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.799513 SP1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.633563 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral septal nucleus, intermedio-ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11804 H3K27ac_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-XBEW-0002-SM-4AT5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.60482 NCI-H2052 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05158 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -3.22113 colorectal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.234878 PSMD10 Pathway Commons Protein-Protein Interactions 1.0 null estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850208 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05129 periventricular stratum of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33771 OE33 CCLE Cell Line Gene CNV Profiles 1.0 1.88055 EP300 ENCODE Transcription Factor Targets 1.0 null GTEX-SE5C-0006-SM-4BRW5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26526 SCC-4 GDSC Cell Line Gene Expression Profiles 1.0 1.73284 luteal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.324239 H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SLC25A13 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00573652 Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A6GE-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SMARCB1 ENCODE Transcription Factor Targets 1.0 null GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35775 estradiol_homo sapiens_gpl570_gse11352 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MDAMB453 Achilles Cell Line Gene Essentiality Profiles -1.0 -2.30801 ELK1 ENCODE Transcription Factor Targets 1.0 null bewo HPA Cell Line Gene Expression Profiles -1.0 -1.07646 syndrome GWASdb SNP-Disease Associations 1.0 0.326244 AR ChEA Transcription Factor Targets 1.0 null SW 982 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.94382 SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.68628 CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hypertrophy CTD Gene-Disease Associations 1.0 1.47838 H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-63-A5MR-01A-31R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of DNA-templated transcription GO Biological Process Annotations 2023 1.0 null intermediate stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17739 BRD-K72414522_AZD-5438_MCF10A_3_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Declive (VI), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41557 abnormality of the hand HPO Gene-Disease Associations 1.0 null mucinous adenofibroma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.20915 ELK1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RERFLCAD2 CCLE Cell Line Gene Expression Profiles -1.0 -2.08536 Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.932284 pancreas HPA Tissue Gene Expression Profiles -1.0 -1.01974 MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.917797 PML_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.986766 primary metabolic process GO Biological Process Annotations 2015 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null IRF8 ChEA Transcription Factor Targets 1.0 null GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.943637 Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BCLAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null breastovarian GeneRIF Biological Term Annotations 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null deferoxamine_homo sapiens_gpl91_gse1056 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.75371 MTA1 MSigDB Cancer Gene Co-expression Modules 1.0 null autism GeneRIF Biological Term Annotations 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.94362 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.26239 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.13007 451LU COSMIC Cell Line Gene Mutation Profiles 1.0 null HCFC1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2199 ZR75_1 BioGPS Cell Line Gene Expression Profiles -1.0 -1.56465 dysostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.887618 Carcinoma, Squamous Cell HuGE Navigator Gene-Phenotype Associations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4960-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRF1 ENCODE Transcription Factor Targets 1.0 null male reproductive gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.746277 ATF3 ENCODE Transcription Factor Targets 1.0 null BRCA2 Pathway Commons Protein-Protein Interactions 1.0 null hearing impairment HPO Gene-Disease Associations 1.0 null RNAi_-666_19345177 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null inner CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15925 GTEX-T5JW-0005-SM-3GADE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57329 H3K27ac_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Pyramus (VIII) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16547 bone remodeling disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.842276 posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00581 Perturb_5972_KD_TARDBP_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.97797 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.87757 periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37769 germ layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068518 15572690-SuppTable5b GeneSigDB Published Gene Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMGN3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null REST_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1472 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.00026 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW684 GDSC Cell Line Gene Expression Profiles -1.0 -1.5197 utilizes GeneRIF Biological Term Annotations 1.0 null WM793B COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.153719 GTEX-X8HC-2726-SM-46MUA GTEx Tissue Sample Gene Expression Profiles 1.0 1.08842 GTEX-QLQW-0226-SM-447BJ GTEx Tissue Sample Gene Expression Profiles 1.0 3.23411 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.923895 proteasome GeneRIF Biological Term Annotations 1.0 null JUN ENCODE Transcription Factor Targets 1.0 null H1_Derived_Neuronal_Progenitor_Cultured_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.971933 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.25102 primary auditory cortex (core)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.825603 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BT20 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.84888 CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF7L2 ENCODE Transcription Factor Targets 1.0 null H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null follicular thyroid cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.350743 Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U7-06A-21R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Curated Protein Localization Annotations 1.0 null papillary thyroid carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.218374 Perturb_18605_KO_Pabpn1l_ERP127567 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_3773_KD_CCNK_SRP041162 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 Perturb_8369_KO_Mlxipl_SRP148418 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.33667 GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.881745 TAF1_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PE/CA-PJ15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.948178 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null c143ga GeneRIF Biological Term Annotations 1.0 null 15572690-SuppTable5a GeneSigDB Published Gene Signatures 1.0 null external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.84948 principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67467 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.87295 GTEX-PLZ4-2826-SM-3P617 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17371 Nucleus x Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43573 cell cortex part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.063699 IRF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null NELFE_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06798 H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RNF181 Pathway Commons Protein-Protein Interactions 1.0 null NABP1 Hub Proteins Protein-Protein Interactions 1.0 null OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.19509 organelle part GO Cellular Component Annotations 2015 1.0 null POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null adenocarcinoma; pancreatic neoplasms GAD Gene-Disease Associations 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null vincristine_homo sapiens_gpl570_gse7556 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null osteoporosis DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.842276 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.2342 NRL_Deficiency_GDS2936_631_mouse_Retinas - 2 months GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Folium-tuber vermis (VII), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21752 BAG2 Pathway Commons Protein-Protein Interactions 1.0 null 16207381-Table1Sb GeneSigDB Published Gene Signatures 1.0 null phenotype GeneRIF Biological Term Annotations 1.0 null POLR2A_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null hypersensitivity reaction disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.265494 GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6853 PLC/PRF/5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25503 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.196669 U266B1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.31872 GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.25988 NUDT21 Pathway Commons Protein-Protein Interactions 1.0 null membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.853446 CTCF ENCODE Transcription Factor Targets 1.0 null KAT2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.10515 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.12521 GTEX-VUSG-0008-SM-4KL24 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02022 ovarian disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.267622 SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.896075 H3K27ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05224 H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.03693 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49824 RUNX2-22187159-PCA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11214 estradiol_mus musculus_gpl4134_gse23241 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MYC_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HPAFII CCLE Cell Line Gene CNV Profiles 1.0 1.48881 TROVE2 Hub Proteins Protein-Protein Interactions 1.0 null EST1-17652178-JURKAT-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null nodular goiter DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.613965 GTEX-WCDI-0002-SM-3P61U GTEx Tissue Sample Gene Expression Profiles 1.0 1.69963 SK-MEL-31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.985354 H3255 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 hacat HPA Cell Line Gene Expression Profiles -1.0 -0.858586 MBD4 ENCODE Transcription Factor Targets 1.0 null NFYB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57873 H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Edema CTD Gene-Disease Associations 1.0 1.54281 PSMG1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WHPG-0006-SM-3NMBV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.63202 GTEX-XPT6-0006-SM-4B66Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.88016 myeloma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.128323 H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null CEBPA-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null 19204204-SupplementaryTable7 GeneSigDB Published Gene Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.53206 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.55103 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6445 18310505-TableS7 GeneSigDB Published Gene Signatures 1.0 null primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.197766 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.02181 AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.243645 H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null inhibin b complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.786902 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.43755 SW480 CCLE Cell Line Gene Expression Profiles 1.0 1.55981 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null THAP1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMD8 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5963_KD_SETDB1_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.43718 vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053552 TGFBR2_knockout_293_GSE46211 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.96856 osteoclasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.01675 GTEX-XBEW-0006-SM-4AT4E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22677 Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.39693 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.47171 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null locus ceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10914 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null pontine nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.65658 Leukemia, Adult T Cell_Blood monocyte_GSE10789 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.317 GTEX-RTLS-2326-SM-46MUH GTEx Tissue Sample Gene Expression Profiles 1.0 1.17864 hearing abnormality HPO Gene-Disease Associations 1.0 null extracellular region COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.281085 Uterine Carcinosarcoma_UCS_TCGA-N7-A59B-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2803-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMD7 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.95641 EEF1G Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.970327 Perturb_5835_KO_miR144/451_SRP119158 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.48212 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.862067 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47888 H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Primary somatosensory area, upper limb, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43275 Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null aplasia/hypoplasia affecting the anterior segment of the eye HPO Gene-Disease Associations 1.0 null GTEX-XMD3-2326-SM-4AT5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.00318 NCI H23 BioGPS Cell Line Gene Expression Profiles 1.0 0.896424 Absent Finger DisGeNET Gene-Disease Associations 1.0 null RUNX1-22897851-JUKARTE6-1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null complexes GeneRIF Biological Term Annotations 1.0 null A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.49704 cerebellum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42835 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03883 H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Hepatic Cirrhosis_Hepatic Tissue_GSE1843 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.21625 NCIH2052 CCLE Cell Line Gene CNV Profiles -1.0 -1.32196 RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03468 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.955983 EEF2 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.83983 leiomyoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.137585 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.05088 GTEX-TKQ2-0004-SM-3NMAC GTEx Tissue Sample Gene Expression Profiles 1.0 1.30053 abnormality of the inner ear HPO Gene-Disease Associations 1.0 null TRIM28_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-5259-01A-31R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null three GeneRIF Biological Term Annotations 1.0 null 19505326-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SIRT6 ENCODE Transcription Factor Targets 1.0 null Primary somatosensory area, barrel field, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34745 ZEB1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.240148 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null E2F1-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.55103 core GeneRIF Biological Term Annotations 1.0 null ELF1_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17910759-TableS5 GeneSigDB Published Gene Signatures 1.0 null COLO679 CCLE Cell Line Gene CNV Profiles 1.0 1.4038 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.36642 auditory vesicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236921 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X4XY-0011-R8A-SM-46MVC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930391 GTEX-RWS6-0005-SM-2XCAN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.77551 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung transplant rejection_Lung Tissue_GSE2018 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.52175 GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.20207 PAAF1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ectoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.071927 GTEX-RWSA-0008-SM-47JYX GTEx Tissue Sample Gene Expression Profiles 1.0 1.37141 Pyramus (VIII), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15548 H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.61064 SIN3A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null synapse part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.095107 DEK MSigDB Cancer Gene Co-expression Modules 1.0 null GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null GSS CCLE Cell Line Gene Expression Profiles -1.0 -2.34941 element GeneRIF Biological Term Annotations 1.0 null SETDB1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain stem glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.513802 GTEX-V1D1-0006-SM-3NMCE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.992554 Prostate adenocarcinoma_PRAD_TCGA-HC-A6AP-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBTF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nervous System Diseases CTD Gene-Disease Associations 1.0 1.31059 GABPA ENCODE Transcription Factor Targets 1.0 null H3K4me1_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SZT2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00649368 MG63 CCLE Cell Line Gene CNV Profiles -1.0 -1.34846 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.23625 GTEX-X261-0011-R7A-SM-4E3JJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847791 primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39957 GTEX-P4PQ-0126-SM-2S1NM GTEx Tissue Sample Gene Expression Profiles 1.0 1.14911 Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4207 H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ADRM1 Pathway Commons Protein-Protein Interactions 1.0 null HT1080 BioGPS Cell Line Gene Expression Profiles -1.0 -1.13425 16651409-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45658 COV644 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06798 H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ChIP_JARID1A_20064375 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K27ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27123 magnocellular division of VA Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13965 GTEX-OIZH-0126-SM-2HMIS GTEx Tissue Sample Gene Expression Profiles 1.0 2.16231 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.967338 HEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.31264 inner CP in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07114 MCM3AP Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35924 TAF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.06875 NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.896949 Simple lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15513 Sarcoma_SARC_TCGA-JV-A5VF-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-CA-04-2009(H1N1)_24Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.54797 ZBTB7A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.794792 striatum_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.91225 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.866233 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83321 testis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.850005 r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00125 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHH2 CCLE Cell Line Gene CNV Profiles 1.0 1.36266 Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BANK1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00584799 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74255 BRCA1 Pathway Commons Protein-Protein Interactions 1.0 null globus pallidus, external segment, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.829452 MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null repair GeneRIF Biological Term Annotations 1.0 null NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895439 GM1600 BioGPS Cell Line Gene Expression Profiles 1.0 1.00616 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0846 CPSF3L Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XUJ4-0126-SM-4BOP7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.999237 GTEX-RWS6-0001-SM-3NMAL GTEx Tissue Sample Gene Expression Profiles 1.0 1.1573 t47d HPA Cell Line Gene Expression Profiles -1.0 -1.87179 screening GeneRIF Biological Term Annotations 1.0 null pelvic varices DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.168381 nucleus LOCATE Curated Protein Localization Annotations 1.0 null SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 GTEX-TKQ1-0006-SM-33HBI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15218 SLR26 CCLE Cell Line Gene Expression Profiles 1.0 1.41381 CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4, COUP MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22242 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.842276 PSME3 Pathway Commons Protein-Protein Interactions 1.0 null MDA-MB-361 GDSC Cell Line Gene Expression Profiles -1.0 -1.53167 KPL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21818 GATA3 ENCODE Transcription Factor Targets 1.0 null GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08016 r9 part of nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.42107 SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GABPA_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM4A ENCODE Transcription Factor Targets 1.0 null GATA1 ENCODE Transcription Factor Targets 1.0 null cases GeneRIF Biological Term Annotations 1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.52116 H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PML_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cerebellum BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.918462 Right_Atrium Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.845637 JHESOAD1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.03004 BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AGS Achilles Cell Line Gene Essentiality Profiles -1.0 -1.41018 posteroventral (inferior) parietal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.98694 BRCA1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GABPA_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cystic Fibrosis_Pancreas_GSE769 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.33291 Split-Hand/Foot Malformation DisGeNET Gene-Disease Associations 1.0 null carbinoxamine-3466 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PSMD6 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 2.24447 OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.18021 H3K27ac_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null E2F4 ENCODE Transcription Factor Targets 1.0 null female reproductive organ benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.132507 OVCAR8_OVARY CCLE Cell Line Proteomics 1.0 2.11937 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 2.13289 NCVADR RES BioGPS Cell Line Gene Expression Profiles -1.0 -2.84646 Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Weight Gain CTD Gene-Disease Associations 1.0 1.16401 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null clitoris TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.48087 upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.29287 hypothyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.40395 GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.925734 GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.853391 putamen, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.883277 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A78R-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pancreas GTEx Tissue Gene Expression Profiles -1.0 -1.25479 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -2.89575 plasmacytoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.36302 GTEX-OXRO-0126-SM-2YUN4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19275 superficial stratum of the PBC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24258 GTEX-R53T-0005-SM-3GADK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04961 CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null presynaptic cytoskeletal matrix assembled at active zones COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.265677 RAC3-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null m1AD (DM) part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06556 PSMA7 Pathway Commons Protein-Protein Interactions 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.24294 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.196779 EBNA2-21746931-IB4-LCL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14527 NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.935182 icSARS CoV_48Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.78845 FGFR3_KD_GDS4454_79_human_RT112 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00558 GTEX-S7SF-0008-SM-3NM8T GTEx Tissue Sample Gene Expression Profiles 1.0 0.903465 MS4A10 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00554461 BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.2382 anovulation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.324823 GTEX-Q734-0006-SM-2I3FJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07229 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18769 GTEX-P4QS-1326-SM-3NMCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.07486 H3K4me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KMS-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.986766 posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.836975 A1207 CCLE Cell Line Gene Expression Profiles 1.0 1.45211 Perturb_4_KO_Pabpn1l_SRP226170 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Parabrachial nucleus, lateral division, dorsal lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35144 H3K27ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_5 ENCODE Histone Modification Site Profiles 1.0 null ARHGAP27 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00699588 ventrolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.47241 Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRO-0011-R2A-SM-3NB1W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.956893 ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.06843 PSMD11 Pathway Commons Protein-Protein Interactions 1.0 null folds GeneRIF Biological Term Annotations 1.0 null intermediate stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10955 Perturb_12618_KD_SREBF2_SRP281894 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 8.11829 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nuclear dna-directed rna polymerase complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 GTEX-WK11-2726-SM-3NMAQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.983568 CBX3_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary auditory cortex (core)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.884152 infratentorial cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.379997 adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.633953 disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 cellular_component GO Cellular Component Annotations 2015 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null C3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00610475 NCIH69 CCLE Cell Line Gene CNV Profiles 1.0 1.49024 H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.65342 LUDLU1 CCLE Cell Line Gene Expression Profiles 1.0 1.7254 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UBR5 Pathway Commons Protein-Protein Interactions 1.0 null synostosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.91308 RFX5_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_erythroblast_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null robust GeneRIF Biological Term Annotations 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.866842 POLR2A_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TXNRD1 Pathway Commons Protein-Protein Interactions 1.0 null icSARS CoV_54Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.4995 GTEX-V1D1-0003-SM-3NMDP GTEx Tissue Sample Gene Expression Profiles 1.0 1.31715 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88483 cerevisiae GeneRIF Biological Term Annotations 1.0 null Breast Neoplasms CTD Gene-Disease Associations 1.0 1.26825 TAF1_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.953698 GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -3.39736 primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.857082 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.841269 Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null placenta cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.619442 16651409-SuppTable1 GeneSigDB Published Gene Signatures 1.0 null GTEX-S33H-0005-SM-2XCAL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05774 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.84475 PSME1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09761 mediodorsal nucleus of thalamus_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.3147 PANC0813 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.45744 brain cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.092421 PSMC2 MSigDB Cancer Gene Co-expression Modules 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null eGFP-JUNB_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.51866 59M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.48571 HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.780472 MYC_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null KDM5C LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00448084 granulocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.158649 RBM33 Pathway Commons Protein-Protein Interactions 1.0 null internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53838 alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null heterocycle metabolic process GO Biological Process Annotations 2015 1.0 null integrator complex GO Cellular Component Annotations 2015 1.0 null head of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.40375 TCF4 ChEA Transcription Factor Targets 1.0 null SIN3A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82712 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null clinical modifier GWASdb SNP-Phenotype Associations 1.0 0.34792 POLR2AphosphoS5_SK-N-MC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 17210682-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null H3K27ac_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.76425 NCI-H2081 GDSC Cell Line Gene Expression Profiles 1.0 2.03151 Central linear nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16148 Liver Cirrhosis CTD Gene-Disease Associations 1.0 1.05052 developmental disorder of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 r3 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31793 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EGR1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.983808 JMSU1 CCLE Cell Line Gene CNV Profiles -1.0 -1.40104 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-1343 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.15757 intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null PSMD13 Pathway Commons Protein-Protein Interactions 1.0 null Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.16285 MAFK_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QH-01A-21R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null thyroid cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.429642 intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 GTEX-S7SE-0005-SM-2XCEA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03472 Peripheral Nervous System Diseases CTD Gene-Disease Associations 1.0 2.88009 H3K27ac_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.14846 NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.957766 Carcinoma CTD Gene-Disease Associations 1.0 1.23137 RCOR1 ChEA Transcription Factor Targets 1.0 null TAF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBE2G2 Pathway Commons Protein-Protein Interactions 1.0 null Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67515 CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR2F2 ENCODE Transcription Factor Targets 1.0 null WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZH-0005-SM-3DB72 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12 CAL51 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.933536 GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4965 PLIN5_OE_GSE44192_482_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A5UA-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPI1-22096565-GC-B-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Main olfactory bulb, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04464 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.998097 GTEX-WH7G-0826-SM-4LVMR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.870716 H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.851096 H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Fibrosis CTD Gene-Disease Associations 1.0 1.18554 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54392 aplasia/hypoplasia affecting the uvea HPO Gene-Disease Associations 1.0 null H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TCF7L2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF8 ChEA Transcription Factor Targets 1.0 null SCC4 CCLE Cell Line Gene CNV Profiles 1.0 2.70605 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.3547 Sarcoma_SARC_TCGA-VT-A80J-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null E2F6_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LY-01A-31R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01987 H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05224 ETS1 ENCODE Transcription Factor Targets 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HCC38 CCLE Cell Line Gene CNV Profiles 1.0 1.50978 SmoothMuscle BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.45386 ATF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H441 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 inhibin a complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.638861 POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null thyroiditis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.397843 Perturb_1712_KO_Cxcr4_SRP217256 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.25517 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40722 GABPA_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Frontal pole, cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22638 GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05777 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD23B Pathway Commons Protein-Protein Interactions 1.0 null spinal trigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01984 GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930745 SREBF2 ChEA Transcription Factor Targets 1.0 null MAZ_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0011-R10A-SM-3DB7O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.845536 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.43709 chlorambucil_homo sapiens_gpl570_gds2970 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null lymphoid cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.277549 17210682-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null EEF1A1 Pathway Commons Protein-Protein Interactions 1.0 null H3K9ac_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null AR-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POLR2A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16323 JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.851419 GK_KO_GDS2610_162_mouse_Brown adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null double-strand break repair GO Biological Process Annotations 2015 1.0 null rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37769 GTEX-XUZC-0226-SM-4BOO7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.29517 GTEX-OHPK-2426-SM-3MJGH GTEx Tissue Sample Gene Expression Profiles 1.0 1.01914 H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SKP1 MSigDB Cancer Gene Co-expression Modules 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.20148 Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06207 GATA1_erythroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAL-148 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.50546 limbic system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A4DS-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F2 ChEA Transcription Factor Targets 1.0 null H3K9ac_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LN340 CCLE Cell Line Gene Expression Profiles 1.0 1.79693 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03496 Meningeal Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null RPF2 Pathway Commons Protein-Protein Interactions 1.0 null r2 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06556 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0943 Perturb_5476_OE_Sox9_SRP375106 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.73783 V, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23817 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.29298 GTEX-X88G-0004-SM-47JZ6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22875 IST-SL1 GDSC Cell Line Gene Expression Profiles 1.0 1.84004 hsa-miR-26b-5p MiRTarBase microRNA Targets 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Carcinoma, Squamous Cell CTD Gene-Disease Associations 1.0 2.88009 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.42583 V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.11258 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF1_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SU-DHL-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.851419 pallidohypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01956 superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55564 NCI-H1993 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 acquired polycythemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.560616 bone disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.298371 CHD2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-A74O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13952 H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid_5d HPA Tissue Sample Gene Expression Profiles -1.0 -0.965322 YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-0008-SM-4DM5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.15871 organelle lumen COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Anridia DisGeNET Gene-Disease Associations 1.0 null PRDX3 MSigDB Cancer Gene Co-expression Modules 1.0 null H3K4me3_K562_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null homologous GeneRIF Biological Term Annotations 1.0 null cortical cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.128278 H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.227707 Perturb_4614_KD_Etv5_SRP231452 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.99712 H3K4me3_erythroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.51157 MYBL2_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MHHCALL4 CCLE Cell Line Gene Expression Profiles -1.0 -1.53932 P300-27268052-CHIP-SEQ-BCELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null decitabine_homo sapiens_gpl571_gse29077 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null 19408105-SuppTable4 GeneSigDB Published Gene Signatures 1.0 null lateral mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.46611 KALS1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.42525 GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles 1.0 0.825647 thyroid nodule TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.671692 CD58 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00495702 Perturb_5498_KD_Prmt1_SRP167901 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.31507 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.855661 TP63 ChEA Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD7_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.968544 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pancreatic Neoplasms CTD Gene-Disease Associations 1.0 1.21695 aplasia/hypoplasia involving the skeleton HPO Gene-Disease Associations 1.0 null NFIC_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36521 H3K27ac_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30356 Transplanted Heart Complication_Myocardial tissue_GSE582 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.19048 H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain GTEx Tissue Gene Expression Profiles -1.0 -0.897999 H3K27ac_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19475 CREB1-20920259-GC1-SPG-MOUSE ChEA Transcription Factor Targets 2022 1.0 null b-lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090988 YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZM-0226-SM-4DXTA GTEx Tissue Sample Gene Expression Profiles 1.0 0.864257 H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84985 dexamethasone_mus musculus_gpl1261_gds2802 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.926593 dna metabolic process GO Biological Process Annotations 2015 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 3.17272 PHF8 ENCODE Transcription Factor Targets 1.0 null BronchialEpithelialCells BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.14127 GTEX-U8XE-0005-SM-3DB8I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871617 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.879177 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.36956 carbohydrate metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.243645 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null C1QA LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00417021 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GABPA_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OOBJ-0006-SM-2I3F4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1507 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04593 kidney TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057897 sexual disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.299812 ZNF274 ENCODE Transcription Factor Targets 1.0 null GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.963038 GTEX-PWOO-0006-SM-2I3E3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01169 primary motor cortex (area M1, area 4)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.873177 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H3-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bone Density DisGeNET Gene-Phenotype Associations 1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.34398 AQP9 Hub Proteins Protein-Protein Interactions 1.0 null TEAD4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TXNL1 Pathway Commons Protein-Protein Interactions 1.0 null YY1_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null HMGN3 ENCODE Transcription Factor Targets 1.0 null bleomycin_mus musculus_gpl81_balbc_gds251 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null CKAP5 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.14568 Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amenorrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.960797 nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.80636 umbilical cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.091102 nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 NCIH2228 CCLE Cell Line Gene CNV Profiles -1.0 -1.82553 GTEX-XMK1-0005-SM-4B665 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11506 Acute Myeloid Leukemia_LAML_TCGA-AB-2985-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Colorectal Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null CLPP_KO_GSE40207_382_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null intermediate stratum of r4Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33893 H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null KDM6A-18722178-U937-AND-SAOS2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K36me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cryptorchidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.272597 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.36242 H3K27ac_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CREB1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300 ChEA Transcription Factor Targets 1.0 null genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.203604 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46037 LN235 CCLE Cell Line Gene Expression Profiles 1.0 1.42896 P68-20966046-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.899751 CCNT2 ENCODE Transcription Factor Targets 1.0 null termporal pattern GWASdb SNP-Phenotype Associations 1.0 0.435659 Perturb_2127_KO_SUMO2_SRP299611 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 r9 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49551 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null YY1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-DX-A3M2-01A-21R-A22K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10177 Perturb_5946_KD_PRDM15_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -3.25184 16643655-1300GenesList GeneSigDB Published Gene Signatures 1.0 null double-strand break repair via homologous recombination GO Biological Process Annotations 2015 1.0 null H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PCI-15A COSMIC Cell Line Gene CNV Profiles 1.0 2.283 UBC Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5973_KD_TCF25_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.65256 H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_PFSK-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1897 CCLE Cell Line Gene Expression Profiles 1.0 2.40652 GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13603 CCNT2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.837833 AP1S2 ChEA Transcription Factor Targets 1.0 null GTEX-V1D1-0008-SM-4JBIJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.27334 BAG6 Pathway Commons Protein-Protein Interactions 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.975357 GTEX-SNMC-0826-SM-4DM66 GTEx Tissue Sample Gene Expression Profiles 1.0 0.863822 GTEX-XYKS-0005-SM-4BRUD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.06751 UBE3A Pathway Commons Protein-Protein Interactions 1.0 null worse GeneRIF Biological Term Annotations 1.0 null impair GeneRIF Biological Term Annotations 1.0 null Liver Neoplasms, Experimental CTD Gene-Disease Associations 1.0 1.30819 disease of mental health DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.847768 EIF3C Pathway Commons Protein-Protein Interactions 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-39-5016-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sensorineural hearing impairment HPO Gene-Disease Associations 1.0 null HEYA8 CCLE Cell Line Gene CNV Profiles -1.0 -1.6659 GTEX-WEY5-0526-SM-3GIKZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.986018 bound GeneRIF Biological Term Annotations 1.0 null H3K4me3_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_17307_KD_Chrm5_SRP222274 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 6.78118 GTEX-X88G-0006-SM-47JX5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02395 PFDN2 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00380075 GTEX-QDVJ-0005-SM-2TC5X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.983025 reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.09253 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dna-directed rna polymerase complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2223 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.827565 RVH-421 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S4UY-0006-SM-3K2A7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02358 MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -1.32618 GTEX-VUSH-0005-SM-3NB2H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17482 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -2.01914 H3K4me3_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Perturb_8988_KD_HNRNPC_SRP329785 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.971254 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41005 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.35924 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.828855 CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-S4P3-0008-SM-3NM8R GTEx Tissue Sample Gene Expression Profiles 1.0 0.985355 catalytic complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.002275 Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J7-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.988032 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null POLR2A_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CSNK2B MSigDB Cancer Gene Co-expression Modules 1.0 null phenotypic abnormality HPO Gene-Disease Associations 1.0 null COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.22232 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.95448 POLR2A_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null female pudendum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.175047 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34207 H3K27ac_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Extragonadal Seminoma DisGeNET Gene-Disease Associations 1.0 null congenital hypothyroidism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.393374 16203770-TableS1 GeneSigDB Published Gene Signatures 1.0 null forelimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.248361 KLF6-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null helixturnhelix GeneRIF Biological Term Annotations 1.0 null ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.183288 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_1430_KO_Adm2_SRP399375 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 4.48604 GTEX-NPJ8-1926-SM-3MJGB GTEx Tissue Sample Gene Expression Profiles 1.0 0.890383 H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Squamous Cell Carcinoma DisGeNET Gene-Disease Associations 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.904433 CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ftc-133 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.422673 RNR2 Hub Proteins Protein-Protein Interactions 1.0 null TBP ENCODE Transcription Factor Targets 1.0 null 18689800-TableS7 GeneSigDB Published Gene Signatures 1.0 null Declive (VI) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41423 GTEX-T2IS-0008-SM-4DM75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16581 cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.077064 POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1323 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Perturb_4482_KO_Silc1_SRP134051 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.51514 primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896183 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null red nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.99389 H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q734-0426-SM-48TZX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.975674 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.371245 TAF1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XUYS-0002-SM-47JXL GTEx Tissue Sample Gene Expression Profiles 1.0 1.58502 H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854125 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.56011 PLA2G4A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00337926 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_MEL cell line_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTF2B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASH2L ChEA Transcription Factor Targets 1.0 null brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.945226 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SKCO1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.16676 Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_4651_KO_Tip55_SRP134924 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.06723 H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1-33199912-293T-HUMAN-KIDNEYEMBRYO ChEA Transcription Factor Targets 2022 1.0 null VDR-23849224-CD4+-HUMAN ChEA Transcription Factor Targets 2022 1.0 null inner CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3715 GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -3.68409 H3K27ac_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Perturb_11759_OE_Ddah1_SRP027595 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.38511 GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12419 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55766 epithelioid trophoblastic tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.522659 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HS 683 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.938114 CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null benign neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.320817 GTF2F1 ENCODE Transcription Factor Targets 1.0 null POLR2A_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASGR1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00594877 Secondary motor area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21087 Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LXF289 CCLE Cell Line Gene Expression Profiles -1.0 -2.02978 metformin-1 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null anterior digastric muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.86278 dlx6 GeneRIF Biological Term Annotations 1.0 null POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.916454 caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39013 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03706 SND1 Pathway Commons Protein-Protein Interactions 1.0 null suz12_17339329_mouse_embryonic_stem_cell_es_cell_lof_mouse_gpl1261_gse31354 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.5585 r6 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17981 Superior olivary complex, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32538 H3K27ac_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81223 GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.965162 YY1_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U4B1-0006-SM-3DB8E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18092 ETS1 ChEA Transcription Factor Targets 1.0 null ELF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAV1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00516544 morula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090094 hsa-miR-4729 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.456732 Fatty Liver CTD Gene-Disease Associations 1.0 1.81465 mature teratoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.348614 NY GDSC Cell Line Gene Expression Profiles -1.0 -2.05346 GTEX-S95S-0002-SM-3NM8K GTEx Tissue Sample Gene Expression Profiles 1.0 1.2287 intermediate stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49805 POLR2AphosphoS5_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.02027 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IF-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC9 CCLE Cell Line Gene Expression Profiles -1.0 -1.99768 SNU5 CCLE Cell Line Gene CNV Profiles 1.0 2.17559 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08905 Parabrachial nucleus, medial division, medial medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28559 Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09529 GABPA_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.05023 Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hypopituitarism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.212271 CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.55553 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.10184 POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K18ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-SN8G-0001-SM-3NM8L GTEx Tissue Sample Gene Expression Profiles 1.0 1.35334 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null female reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.925479 intestinal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090998 NALM1 CCLE Cell Line Gene Expression Profiles -1.0 -1.45837 Adenocarcinoma CTD Gene-Disease Associations 1.0 1.23806 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39256 GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 0.894201 H3K36me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ASH2L-23239880-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-OIZG-0005-SM-2HMJC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.999429 GTEX-R55C-0008-SM-48FCF GTEx Tissue Sample Gene Expression Profiles 1.0 0.943948 PSMD12 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WFON-0001-SM-3P61W GTEx Tissue Sample Gene Expression Profiles 1.0 1.87731 cell part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.877092 r5 part of A5 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26586 intermediate stratum of r1Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28807 superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69559 H3K9ac_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.908723 r7 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62488 cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.048984 Acute Myeloid Leukemia_LAML_TCGA-AB-2984-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041725 nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.053052 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.82357 PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null pyrazinamide-2478 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null thyroid carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.427765 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.846443 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.286 E2F6_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H4K5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_PFSK-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOS_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.980752 Leukemialymphoblastic(MOLT-4) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.33537 19204204-SupplementaryTable1 GeneSigDB Published Gene Signatures 1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.413912 Perturb_4256_KD_NCOR2_SRP326059 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.42212 ZBTB7A ENCODE Transcription Factor Targets 1.0 null Perturb_5942_KD_PIAS2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.1655 IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null POU5F1-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null extracellular space COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.285507 Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null germ cell cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.248203 H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.403438 Perturb_13076_KO_Atmin_SRP062722 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 ELK1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HPAF-II COSMIC Cell Line Gene CNV Profiles 1.0 2.283 GNLY LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00722109 TRIM28_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WRHU-1226-SM-4E3IJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898204 aplasia/hypoplasia affecting the eye HPO Gene-Disease Associations 1.0 null colorectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056158 cingulum bundle, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46716 enhancer GeneRIF Biological Term Annotations 1.0 null EP300_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EEF1A2 Pathway Commons Protein-Protein Interactions 1.0 null cingulate gyrus, parietal part, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.900152 CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.36563 HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.850091 Vincristine CTD Gene-Chemical Interactions 1.0 null HS 839.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.21147 NCIH1975 Achilles Cell Line Gene Essentiality Profiles 1.0 2.31565 COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.960424 MBD4 MSigDB Cancer Gene Co-expression Modules 1.0 null DOHH-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848223 tolazoline-1918 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Taenia tecta, dorsal part, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05282 GTEX-XUZC-1026-SM-4BOPY GTEx Tissue Sample Gene Expression Profiles 1.0 0.857191 fat_a.V1 HPA Tissue Sample Gene Expression Profiles 1.0 1.13079 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-QC-A6FX-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null urinary system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056024 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null captopril_mus musculus_gpl1261_gds3683 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null SUM225CWN Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.87238 SF1 MotifMap Predicted Transcription Factor Targets 1.0 null dlx5 GeneRIF Biological Term Annotations 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06658 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.08823 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14345 ChIP_ZFX_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SP3 MSigDB Cancer Gene Co-expression Modules 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30878 presynaptic active zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.241356 Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WQUQ-0006-SM-3MJF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.13657 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24428 Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral tuberal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.16235 POLR2A_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null positive regulation of transcription by RNA polymerase II GO Biological Process Annotations 2023 1.0 null PML_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TSE9-0011-R9A-SM-3DB7Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.862122 GTEX-QVJO-0008-SM-447AU GTEx Tissue Sample Gene Expression Profiles 1.0 0.909252 H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null dorsal thalamus_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.95838 H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.95419 POMP Pathway Commons Protein-Protein Interactions 1.0 null SNU-C2B COSMIC Cell Line Gene Mutation Profiles 1.0 null COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -0.854105 cytoplasm LOCATE Curated Protein Localization Annotations 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15842 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12306 GTEX-OHPL-0008-SM-4E3I9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.88894 A4FUK CCLE Cell Line Gene CNV Profiles 1.0 1.37611 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null IRF1 ENCODE Transcription Factor Targets 1.0 null organism form TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.6144 monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042146 VIIAt Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.95788 hth GeneRIF Biological Term Annotations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.20789 UBA7 Pathway Commons Protein-Protein Interactions 1.0 null 16643655-306GenesList GeneSigDB Published Gene Signatures 1.0 null Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYJK-0005-SM-3NMA1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07209 hypertrophy of breast DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.604201 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08213 ITK_knockout_241_GSE12465 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.8598 SARS-ddORF6_24Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.68487 Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HR-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone resorption disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.842276 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.63443 alterations GeneRIF Biological Term Annotations 1.0 null SNU-C5 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.867623 response to stress GO Biological Process Annotations 2015 1.0 null inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.979692 POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01418 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAC1 MSigDB Cancer Gene Co-expression Modules 1.0 null SK-OV-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.77584 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.31323 Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-7173-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.97587 NCIH226_LUNG CCLE Cell Line Proteomics 1.0 3.22878 Lung squamous cell carcinoma_LUSC_TCGA-18-3406-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basophil TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.19653 mantle zone of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08812 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.880638 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null leydig cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.78522 GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44206 RCOR1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain stem cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.491597 RMGI Achilles Cell Line Gene Essentiality Profiles -1.0 -1.46738 outer CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5389 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24024 OE33 COSMIC Cell Line Gene CNV Profiles 1.0 2.283 H3K36me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of limb bone HPO Gene-Disease Associations 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.16288 HS 69ST Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.24912 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14076 Primary somatosensory area, trunk, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18579 Perturb_5943_KD_POLDIP3_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.96041 BAG3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles 1.0 1.43368 POLR2A_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.973614 other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.23604 FKBP1A LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0036712 liver_d HPA Tissue Sample Gene Expression Profiles 1.0 1.21152 primary motor cortex (area M1, area 4)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.97922 GTEX-PWOO-0326-SM-48TDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.86191 Parabrachial nucleus, lateral division, ventral lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86201 adrenal gland GTEx Tissue Gene Expression Profiles 1.0 1.60689 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24428 Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.79281 CGTH-W-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lymphocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.279307 myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045015 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.47195 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GOLIM4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.0054134 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-4494-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.23048 dexamethasone_mus musculus_gpl81_gds2266 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.30208 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24457 Hiv Infections DisGeNET Gene-Disease Associations 1.0 null EPLC272H CCLE Cell Line Gene CNV Profiles 1.0 2.18827 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null conjunction GeneRIF Biological Term Annotations 1.0 null 20368555-TS-1 GeneSigDB Published Gene Signatures 1.0 null NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.895863 protein binding GO Molecular Function Annotations 2015 1.0 null layer 1 of PCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00071 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null reduced GeneRIF Biological Term Annotations 1.0 null intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TML8-0005-SM-32QPA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.65498 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18198 primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.22451 EGR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11695 TAF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EWS-ERG-20517297-CADO-ES1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K56ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36179 protein complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 brca2 GeneRIF Biological Term Annotations 1.0 null H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NOMO1 CCLE Cell Line Gene CNV Profiles 1.0 1.82981 NCIH2122 Achilles Cell Line Gene Essentiality Profiles 1.0 1.05151 CUX1 ChEA Transcription Factor Targets 1.0 null specific developmental disorder DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 A-CA-04-2009(H1N1)_12Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.73465 Lung squamous cell carcinoma_LUSC_TCGA-22-4591-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.62864 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06716 MEF2A ChEA Transcription Factor Targets 1.0 null Glioma HuGE Navigator Gene-Phenotype Associations 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.674809 colonrectum_f HPA Tissue Sample Gene Expression Profiles 1.0 1.14864 MDA-MB-468 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05158 POLR2AphosphoS5_SK-N-MC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42H-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3591-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 POLR2A_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adenoma HuGE Navigator Gene-Phenotype Associations 1.0 null r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14455 lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.271604 brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043498 CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.37484 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.92462 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02945 GTEX-OHPL-0006-SM-3MJHB GTEx Tissue Sample Gene Expression Profiles -1.0 -1.64191 OVCAR5 BioGPS Cell Line Gene Expression Profiles -1.0 -1.65717 hindlimb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.287092 EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.69724 Perturb_13086_OE_Kdm6a_SRP225522 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.89299 USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null trophoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.256902 nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.41962 TAF1_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null saccharomyces GeneRIF Biological Term Annotations 1.0 null GTEX-UPJH-0006-SM-3GACW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18529 MARCH6 Pathway Commons Protein-Protein Interactions 1.0 null Perturb_5948_KD_PRRX2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.93704 corpus luteum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.623043 mesoderm TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067551 GTEX-NL3H-0011-R1a-SM-48TDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.93194 female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.797462 male infertility DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.633169 Poisoning CTD Gene-Disease Associations 1.0 1.42859 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.03722 H3K36me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null cancer GAD High Level Gene-Disease Associations 1.0 0.293278 GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -2.20133 POLR2A_GM12892_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PLZ6-0226-SM-3P61I GTEx Tissue Sample Gene Expression Profiles 1.0 2.36988 Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20658 Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hypersensitivity reaction type ii disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.192344 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03917 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.21206 mantle zone of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13988 GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.91473 CREB1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11689 Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_1969_KO_Grn_SRP314934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.36581 spinal column TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.116279 GTEX-XGQ4-0226-SM-4GIDS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.844274 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19987 GTEX-P78B-1926-SM-3P616 GTEx Tissue Sample Gene Expression Profiles 1.0 0.852023 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23755 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848223 H3K79me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62382 mature ovarian follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.726918 Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null blood cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058649 JUND ENCODE Transcription Factor Targets 1.0 null MAFK_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urinary tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055834 FMNL1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.0055195 cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55512 POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T2YK-0008-SM-4DM6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.935809 H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null proteasome complex GO Cellular Component Annotations 2015 1.0 null H3K4me3_MEL cell line_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Perturb_730_KD_ELAVL1_SRP293637 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -2.2194 H3K27ac_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOSL1 ENCODE Transcription Factor Targets 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null heart TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14116_KD_RPS6KB1_SRP187713 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.35462 POLR2A_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null syndactyly DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.22345 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.906206 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null UBTF ENCODE Transcription Factor Targets 1.0 null GTEX-XYKS-0002-SM-4BRWN GTEx Tissue Sample Gene Expression Profiles 1.0 1.54762 Lung adenocarcinoma_LUAD_TCGA-64-5781-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.66743 GATA3-27048872-CHIP-SEQ-THYMUS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NFIC_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null GTEX-TMZS-0001-SM-3P61Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.56194 CREB1 ChEA Transcription Factor Targets 1.0 null H3K4me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null etoposide_homo sapiens_gpl10558_gse33990 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null reveals GeneRIF Biological Term Annotations 1.0 null cellular leiomyoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.647348 ethinyl estradiol_mus musculus_gpl75_gds285 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Down Syndrome_CNS - Brain - Cerebellum (MMHCC)_GSE1611 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.73853 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null throat TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.46123 POLR2A_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Type 1 diabetes mellitus_Myocardial tissue_GSE4616 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.24719 HNF4A ChEA Transcription Factor Targets 1.0 null POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NL4W-0006-SM-2I3GH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18525 SG in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.996869 Lung squamous cell carcinoma_LUSC_TCGA-90-7769-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prelimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.5063 Lung adenocarcinoma_LUAD_TCGA-55-A492-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_10356_KD_BRD4_SRP093774 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 SUM 1315M02 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.936605 DYNLRB1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00419059 periventricular stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.05371 HS 895.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -2.33307 RMGI CCLE Cell Line Gene CNV Profiles -1.0 -2.07057 abnormality of skeletal morphology HPO Gene-Disease Associations 1.0 null MAFF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver Neoplasms CTD Gene-Disease Associations 1.0 1.7935 limb GeneRIF Biological Term Annotations 1.0 null SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDT8-0006-SM-32PL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.983454 UBE3C Pathway Commons Protein-Protein Interactions 1.0 null Perturb_12844_KO_Ehmt2_SRP269502 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -9.90409 MARCKS LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00649249 cellular aromatic compound metabolic process GO Biological Process Annotations 2015 1.0 null PSMB4 Pathway Commons Protein-Protein Interactions 1.0 null 59M CCLE Cell Line Gene CNV Profiles -1.0 -1.69579 H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null trastuzumab_homo sapiens_gpl6947_gse31432 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MEF2A-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCFC1_ES-E14_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVSAHO_OVARY CCLE Cell Line Proteomics 1.0 3.34582 molecular_function GO Molecular Function Annotations 2015 1.0 null Autism DisGeNET Gene-Disease Associations 1.0 null H3K27ac_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null IRF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3ac_C2C12_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFE2L2-20460467-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916296 16715129-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07365 interstitial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.819412 Uterine Cervical Neoplasms CTD Gene-Disease Associations 1.0 1.3085 DCP1A-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null bone marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073364 dorsal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12374 macromolecular complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 SP2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74829 Dermatomyositis_Muscle - Striated (Skeletal) (MMHCC)_GSE1551 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.57434 HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.03195 Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SX-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NUB1 Pathway Commons Protein-Protein Interactions 1.0 null OCIM1 CCLE Cell Line Gene CNV Profiles 1.0 1.62926 KG-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.72777 IV Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.92501 GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.933154 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Frontal pole, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38943 H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null A-CA-04-2009(H1N1)_12Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.55212 H4K20me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KDM5A-27292631-CHIP-SEQ-BREAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null lateral hypothalamic area, mammillary region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.3297 C32 CCLE Cell Line Gene CNV Profiles 1.0 1.91571 MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12538_KO_FBXO11_SRP278534 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00649 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD3 Pathway Commons Protein-Protein Interactions 1.0 null dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.957307 septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55322 split hand/foot malformation 1 OMIM Gene-Disease Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056398 OB outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16137 nuclear part GO Cellular Component Annotations 2015 1.0 null SUMO2 Pathway Commons Protein-Protein Interactions 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Leukemia_chronicMyelogenousK-562 BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.03516 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JARID1A-20064375-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.914843 GABPA_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SEC14L1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00308254 pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66945 SIRT6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC_Activation - 24 hours_GDS2025_726_mouse_Pancreatic islet beta cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-QMRM-0005-SM-3NB2A GTEx Tissue Sample Gene Expression Profiles -1.0 -2.02698 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0752 H3K4me1_G1E_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null paraventricular nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.935123 17069663-Table4 GeneSigDB Published Gene Signatures 1.0 null RAN MSigDB Cancer Gene Co-expression Modules 1.0 null SIN3A Pathway Commons Protein-Protein Interactions 1.0 null migraine DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.133167 ATF2 ENCODE Transcription Factor Targets 1.0 null superficial stratum of r3Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64845 subset GeneRIF Biological Term Annotations 1.0 null FCN1 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00499375 angstrom GeneRIF Biological Term Annotations 1.0 null cytoplasm GeneRIF Biological Term Annotations 1.0 null anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.91186 PSMG3 Pathway Commons Protein-Protein Interactions 1.0 null PSMC1 Pathway Commons Protein-Protein Interactions 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.03144 ELF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EW8 CCLE Cell Line Gene Expression Profiles 1.0 1.59861 dactinomycin_homo sapiens_gpl7172_gse12459 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.18315 POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ebolavirus(EBOV)_6day_PBMCs_17725815_GSE8317 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.23434 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Parabrachial nucleus, medial division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28807 POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-CA-04-2009(H1N1)_24Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.28548 FOXP2 ENCODE Transcription Factor Targets 1.0 null Cognition Disorders CTD Gene-Disease Associations 1.0 1.48325 Parabrachial nucleus, medial division, external medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58038 varicocele DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.177301 GTEX-QEG5-0226-SM-2I5GI GTEx Tissue Sample Gene Expression Profiles 1.0 0.897875 H3K4me3_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.55886 PPP1CA MSigDB Cancer Gene Co-expression Modules 1.0 null INTS9 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null implicated GeneRIF Biological Term Annotations 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02239 OACP4C COSMIC Cell Line Gene CNV Profiles 1.0 2.283 UBR4 Pathway Commons Protein-Protein Interactions 1.0 null SNU761 CCLE Cell Line Gene Expression Profiles -1.0 -1.49197 choriocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.620617 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01025 USF1_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-A8I2-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-O5YV-0006-SM-2I5GX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.30253 cyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.347778 HCC2218 GDSC Cell Line Gene Expression Profiles -1.0 -2.62602 SPI1-20176806-THIOMACROPHAGE-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.76191 gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Crus II, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34856 SMAD4 ChEA Transcription Factor Targets 1.0 null REST ENCODE Transcription Factor Targets 1.0 null viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03441 MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null USP15 Pathway Commons Protein-Protein Interactions 1.0 null XRN2-22483619-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null histone acetyltransferase binding GO Molecular Function Annotations 2023 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-FB-A5VM-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_12847_KO_Cnot6l_SRP152802 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.0403 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45845 IRF8-22096565-GC-B-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null SK-MEL-30 GDSC Cell Line Gene Expression Profiles -1.0 -2.01329 GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08676 USF2 ENCODE Transcription Factor Targets 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null CEBPB_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.934184 lung_4b HPA Tissue Sample Gene Expression Profiles -1.0 -0.864441 klinefelter's syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.622183 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XBEC-1326-SM-4AT69 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871975 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.951599 HCC1937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.19807 PSMD14 Pathway Commons Protein-Protein Interactions 1.0 null AMO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.02888 RKO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.920745 YY1_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1534 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.936605 crystalloid COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.530028 BRD-K21680192_mitoxantrone_PC3_24_h_10_um LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null crystal GeneRIF Biological Term Annotations 1.0 null PSMG2 Pathway Commons Protein-Protein Interactions 1.0 null HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.08417 liminal part of r3 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09647 DSS1 complex CORUM Protein Complexes 1.0 null POLR2AphosphoS2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MAFK_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Breast Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hydroflumethiazide-1851 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null LU99 CCLE Cell Line Gene CNV Profiles -1.0 -3.01334 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8503 Perturb_14555_KO_ELF3_SRP051606 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -5.20151 superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95195 GTEX-WEY5-0001-SM-3P61Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.94994 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-P4PP-0126-SM-3LK69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13832 Carcinoma, Hepatocellular CTD Gene-Disease Associations 1.0 1.76791 JEKO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.51283 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28703 bone marrow disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.157765 marker GeneRIF Biological Term Annotations 1.0 null hallux TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.442578 EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.839771 bladder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.866186 H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZG-0001-SM-47JYF GTEx Tissue Sample Gene Expression Profiles 1.0 1.0254 TEAD4_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null OPM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.51408 FOS_MCF 10A_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Osteoporosis DisGeNET Gene-Disease Associations 1.0 null Perturb_6528_KO_Trp53/Nf1/Pten/Pot1a/Pot1b_SRP293265 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.13152 VI, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01097 EPLC-272H COSMIC Cell Line Gene CNV Profiles 1.0 2.283 GTEX-QDVJ-0008-SM-48U2E GTEx Tissue Sample Gene Expression Profiles 1.0 0.972847 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.737618 Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71703 RAMOS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.848223 HCC827 Achilles Cell Line Gene Essentiality Profiles 1.0 1.17797 posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07946 Absence Of Hand DisGeNET Gene-Phenotype Associations 1.0 null MTA3 ENCODE Transcription Factor Targets 1.0 null TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Testicular Nonseminoma DisGeNET Gene-Disease Associations 1.0 null HCFC1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 15-delta prostaglandin J2-564 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null layer 1 of FCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23898 GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10488 GTEX-V955-0004-SM-3NMDH GTEx Tissue Sample Gene Expression Profiles 1.0 1.75722 Perturb_5990_KD_ZNF326_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -4.73611 Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SK-CO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 1.11263 Liver Diseases CTD Gene-Disease Associations 1.0 1.67547 chronic GWASdb SNP-Phenotype Associations 1.0 0.435659 Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX2-24655370-MC3T3E1-MOUSE-BONE ChEA Transcription Factor Targets 2022 1.0 null thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.313915 superficial stratum of r5Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06322 AMO-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-K1-A6RV-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.67808 HCoV-EMC2012_7Hour_23631916_GSE45042 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.03855 sex differentiation disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.549359 GTEX-RUSQ-0826-SM-47JWW GTEx Tissue Sample Gene Expression Profiles 1.0 0.958929 rna polymerase complex COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 disease GWASdb SNP-Disease Associations 1.0 0.023631 MZ in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.930361 Perturb_5992_KD_ZNF512_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -9.39065 RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.5205 Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02696 MAX_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TIMD4 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures -1.0 -0.00518899 Perturb_5959_KD_RPF2_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.05377 APECED - Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy_Thymic epithelial cell_GSE85 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.27216 HCFC1 ENCODE Transcription Factor Targets 1.0 null Bone Mineral Density Test DisGeNET Gene-Phenotype Associations 1.0 null primary motor cortex (area M1, area 4)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07399 excretory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054265 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null aplasia/hypoplasia of the iris HPO Gene-Disease Associations 1.0 null Congenital Foot Deformity DisGeNET Gene-Disease Associations 1.0 null multinodular goiter DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.77575 Perturb_376_OE_PRC1/NLS3A_SRP223097 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.75621 Hereditary Breast And Ovarian Cancer Syndrome DisGeNET Gene-Disease Associations 1.0 null CEBPB_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dna repair GO Biological Process Annotations 2015 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.430017 Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.25114 follicular thyroid cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.190106 UACC812 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.763366 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 EP300_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null times GeneRIF Biological Term Annotations 1.0 null GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00772 H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RCOR1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parabrachial nucleus, lateral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14093 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.8513 BV-173 GDSC Cell Line Gene Expression Profiles -1.0 -1.44014 Neurobehavioral Manifestations CTD Gene-Disease Associations 1.0 1.18587 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S95S-0005-SM-2XCEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28549 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FOSL2_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null efo21 HPA Cell Line Gene Expression Profiles 1.0 0.830775 WM-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.938114 H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.94163 CHD1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crus II, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.958186 C32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 2.65932 CLPP_KO_GDS4791_376_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-XLM4-0004-SM-4AT5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.37581 autoimmune disease of endocrine system DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.404931 Perturb_4280_KO_Smchd1_SRP134966 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 14.6397 lateral wings of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43079 MDAMB453 CCLE Cell Line Gene Expression Profiles -1.0 -1.69707 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of the Fc Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.55553 GTEX-XQ8I-1926-SM-4BOOK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.909619 Memory Disorders CTD Gene-Disease Associations 1.0 1.07022 H3K4me3_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null prognosis GeneRIF Biological Term Annotations 1.0 null RB1_KD_GSE50532_659_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24072 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 2.22949 CP-320650-01-3908 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Inclusion Body Myositides_Muscle tissue_GSE3112 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.52906 ME-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.30667 connective tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 nuclear lumen COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.03318 INTS10 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11412 H4K20me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SNMC-0006-SM-2XCFE GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28872 GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.60012 MAP1LC3B Pathway Commons Protein-Protein Interactions 1.0 null RNF219 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WWYW-3126-SM-3NB39 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.836072 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles 1.0 0.84065 GTEX-S32W-0926-SM-4AD5X GTEx Tissue Sample Gene Expression Profiles 1.0 0.840779 GTEX-TKQ2-0006-SM-33HBH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52398 germ cell and embryonal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.191408 Brain Lower Grade Glioma_LGG_TCGA-HT-7684-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.40398 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -1.17497 CCT2 Hub Proteins Protein-Protein Interactions 1.0 null H3K9ac_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.918469 GTEX-N7MS-2326-SM-2HMLD GTEx Tissue Sample Gene Expression Profiles 1.0 0.992905 Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.03078 Perturb_14577_KO_NQO1_SRP217327 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.83488 ELF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 15520196-SuppTable3 GeneSigDB Published Gene Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-A5KJ-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.39396 Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JAK1_activemutant_61_GSE18239 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -2.28397 r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48394 H3K9me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null deferasirox_homo sapiens_gpl570_gds3558 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-UPIC-0002-SM-3NMDC GTEx Tissue Sample Gene Expression Profiles 1.0 1.10686 Anemia CTD Gene-Disease Associations 1.0 1.58491 E2F4_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.95151 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.19534 Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.838179 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null intermediate stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7212 autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046477 CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SARS-CoV_0Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.73445 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles -1.0 -0.856255 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22613 GTEX-U3ZM-0002-SM-3NMDM GTEx Tissue Sample Gene Expression Profiles 1.0 1.14433 UBR7 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14308 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0503 Sensorineural Hearing Loss (Disorder) DisGeNET Gene-Disease Associations 1.0 null hypospadias DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.420641 Kidney BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.86376 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.25979 ATXN2 Pathway Commons Protein-Protein Interactions 1.0 null Global Developmental Delay DisGeNET Gene-Disease Associations 1.0 null GTEX-SIU7-0001-SM-3NMAW GTEx Tissue Sample Gene Expression Profiles 1.0 1.19493 Perturb_5961_KD_SAFB_SRP271175 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -6.28478 GTEX-VUSG-0003-SM-3NMDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.01122 primary auditory cortex (core)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.950613 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CA46 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85568 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null split hand HPO Gene-Disease Associations 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.76284 orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.959799 Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 2.06209 urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.161139 TGFB3 LINCS L1000 CMAP CRISPR Knockout Consensus Signatures 1.0 0.00448238 SIN3A_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null