association	dataset	threshold value	standardized value
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74229
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83628
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.75875
BRD-K68463857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85695
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02586
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.2809
Stomach	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.606049
BRD-K93747042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.128
BRD-K32862383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39082
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43825
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181431_0_v_1_calr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SEH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6626
BRD-K59523233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95703
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84707727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3259
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K89174739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00979
Portio vaginalis cervicis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6141
BRD-K35780971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26486
GSE173873_1_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84239940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34293
BRD-K18768614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50318
BRD-A85231803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10618
Molaris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9714
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0627
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14644
BRD-K96776591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53908
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07609
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57155
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0274
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26484
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76932
abnormal retina blood vessel morphology	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K48662018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01104
PMC10679662-mmc2.xlsx-NC-D3-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06427
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Placental cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Follicular thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_5_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30292003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26996
BRD-A39660642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6358
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62416
BRD-K71605668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71783
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92253
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64189
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4738
RAB5IF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12162
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47498351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28603
GSE123689_1_v_0_cbx8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60288
abnormal gallbladder morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE147893,GSE147897_2_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71355
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45379
BRD-K82774801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06398
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1241
BRD-K72452130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55592
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1805
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1588
BRD-K83872468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09663
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88645787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63112
BRD-K00209945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21604
GSE226249_5_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30674856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31504
GSE243552_1_v_0_gpr107_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93486666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27947
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62584372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20773
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6762
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98720112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62524
BRD-K13672060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65211
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8394
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2387
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
lm1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
BRD-K93159873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11875
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A36774080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24312
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6577
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.04962
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86557
BRD-K72071403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81034
BRD-A24714998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53446
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5809
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.52951
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
enlarged gallbladder	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K80996561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4683
BRD-K81543095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.224
ASB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58364
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.47065
GSE173810_4_v_6_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76788397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0077
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64225
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9588
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84085
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61703
BRD-K45508763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32679
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26634905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53612
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197571_2_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91593159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17583
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMM8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37726
abnormal eye morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0717
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129725_1_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60638
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_3_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_7-Supplementary_Table_7_ETV6-repressed_genes_defined_by_dTAG_at_24_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44131977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62994
BRD-K58445641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18129
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4765
BRD-K48845054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01476
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15746
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25241
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE93918_2_v_3_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6254
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28782
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21911
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4644
BRD-K13526564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29717
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49097
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50355
BRD-K55311609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22512
BRD-K90999585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21395
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GDAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38578
BRD-K57468571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09902
GSE206870,GSE206872_3_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-y_TFEB_KO_LLOMe_VS_WT_LLOMe_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56884
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56619
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN015_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.346
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156115_2_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21679
BRD-K16526787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91664
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45564
GSE120463_1_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03039
BRD-K57115335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91321
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.934
BRD-K18109695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66911
PMC5414054-ncomms15013-s11.xlsx-SupplementaryData10-Supplementary_Data_10_Genes_differentially_expressed_due_to_infection_in_IRF5-_-_compared_to_parent_KOLF2_cells_IRF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE82110,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10130768-LSA-2023-01950_TableS5.xlsx-Genes_repressed_in_Primary_PCa-BAZ2A-TAM_repressed_in_BAZ2A_KDM1A__and_BAZ2A_TOP2A_High_primary_PCa_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35033
BRD-K73540839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11623
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19482
BRD-K32145037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26215
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29058
BRD-K36111748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55572
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K64001802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22704
BRD-K85401814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28139
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48358706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2443
CRCGN017_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56462
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18891
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMPCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49946
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51715
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101336_1_v_2_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11183
Type IC spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0905
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94216
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nthy-ori 3-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
RASAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07689
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18653
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36557327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17976
BRD-K79433629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00786
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76721
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K70428675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27826
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7607
BRD-K69699301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26435
ZNF583	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79163
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.62534
NAGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53559
BRD-K89932793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35942
BRD-K97938633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29795
BRD-K98427581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01554
BRD-K94921631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11729
BRD-K95148987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.81946
BRD-K31021810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20764
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50646
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99059
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74735
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.83172
BRD-K39318389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60752
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.62229
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39925
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25762
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67307
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35154
PAWR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44335
Tooth bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
Type II spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BORA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18876
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158975_0_v_1_spp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186767_1_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46131
BRD-K09995054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07291
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-Down_in_MSC_chond_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4470057-12943_2015_398_MOESM7_ESM.xls-probes_KD_inh_in_common-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
8-M-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32222
PMC7304190-13229_2020_355_MOESM18_ESM.xlsx-Supplemental_Table_5-iPSC_NPCs_TCF4_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8567138-Table_2.xlsx-Sheet1-IGFBP5_AND_IGFBP7_NOT_IGFBP3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
COQ8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12089
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91454
BRD-K04712840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17797
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36923996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02117
BRD-K26992703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61945
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45076
FOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49549
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31149
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0621
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K98474331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78671
BRD-K68041793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04911
BRD-K36725646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11934
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95459450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11771
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53543
BRD-K47541706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5048
BRD-K40841951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74502
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27945483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0349
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15643
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39532
BRD-K07409609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31754
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62445
GSE107581_0_v_1_cd27_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_AND_fMSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24377650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19911
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128099,GSE128159_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K29077209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27803
GSE235550_1_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K41025232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36113
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173873_5_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K90821428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.048
BRD-K34044309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05159
GSE211286_7_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K93516545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97513
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69981
PMC8789288-elife-73137-supp3.xlsx-Gene_List_Comparisons-Supplementary_file_3_Comparison_of_genes_induced_by_IRF1_or_IFNg_with_genes_in_the_type_II_ISG_screen_library_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_and_DHE_p_0_05_1_5FC-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30171122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22803
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50492
BRD-K52468958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21901
HTR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48695
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-ZNF423_targets-target_gene_ZNF423	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84936524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36909
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57179
BRD-K98639224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.093
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_6-Supplementary_Table_6_ETV6-repressed_genes_defined_by_dTAG_at_6_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57848
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69073616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36066
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79665135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24396
BRD-A12822115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26588
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.583078
BRD-K36099605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01261
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29438
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	3.56808
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45265
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235701,GSE261434_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.24592
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07959057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47468
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.89289
GSE100464,GSE100465_0_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36352298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59012
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K72774661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82614
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5944
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48389907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1595
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31510639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46321
BRD-K99331869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54533
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10130768-LSA-2023-01950_TableS5.xlsx-Genes_repressed_in_Primary_PCa-BAZ2A-TAM_repressed_in_BAZ2A_TOP2A_High_primary_PCa_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26459891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38364
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2775
ZMAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22907
PMC7725876-Table_2.xls-Sheet1-Table_2_v1_DEGs_in_the_BESC_were_treated_with_LPS_compared_with_PBS_control_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.46092
FRS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01055
BRD-K84210390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7858
GSE147669_2_v_1_tram2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91282650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20454
BRD-K47535493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24448
ST18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0635
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84271229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04328
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0839
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95844
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09034
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31596
KCNJ11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24272
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99241
BRD-K70712801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87593
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11138
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.53425
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dermatofibroma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55343
BRD-K62758843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21431
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42104
BRD-K78245984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5589
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84519
PMC10318747-12864_2023_9472_MOESM2_ESM.xlsx-OCI-AML3_30min_vs_Control-Unnamed_1_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43605
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8029
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.7513
Ndc80 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77343050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02471
GSE206729_5_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6552
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal skin morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE173282_1_v_0_marchf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15508005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31861
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10772
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K56661847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3738
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43267
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82105033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6142
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.85502
BRD-K06475437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37496
CRCGN008_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14575
GSE165307_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96243955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10907
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82333
BRD-K09146396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6351
BRD-K06428422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62599
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00566460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01879
BRD-K58041870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48022
PMC4521181-oncsis201520x8.pdf-10-ARHGAP35_ARHGAP35	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K02078984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63685
MEWO cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148321,GSE169423_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.35876
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1758
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.48517
BRD-K85311003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18593
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K85307083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21365
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20201
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76785
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1691
BRD-K54272776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32321
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
FNDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13707
BRD-K00914921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98895
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06035
BRD-K45813167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46297
BRD-K23442578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12638
BRD-K03884263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56039
efm19	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
BRD-K46739745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04485
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6913
GSE70935_2_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66425065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6628
Endometriosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.822
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98137
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K71427375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10913
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91777
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K35792251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83438
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62063
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1653
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00258
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TOP1MT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7055
CRCGN016_MCF10A.WT.HP_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33464
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95499061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97898
BRD-K11641139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24793
CTNNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5164
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40705
PMC6766969-PATH-249-90-s006.xlsx-TAB_S2_b-Supplementary_Table_S2_b_Top_100_upregulated_and_downregulated_genes_in_TAF15-NR4A3_vs_EWSR1-NR4A3_engineered_cell_models_NR4A3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17233342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22533
BRD-K15474464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34834
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91122
GSE174751_0_v_1_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59709463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22005
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11345
GSE195559_8_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K17232330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13557
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K45153693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.494
BRD-K00611112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50937
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7976
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7562
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.4554
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94862255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73128
GSE148321,GSE169423_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23966
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.27832
BRD-K30699866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44304
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59984972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68589
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10130768-LSA-2023-01950_TableS5.xlsx-Genes_repressed_in_Primary_PCa-BAZ2A-TAM_repressed_in_BAZ2A_High_primary_PCa_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49103536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47239
BRD-K77958314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28007
BRD-K93613839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12999
BRD-K05417183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04342
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.68371
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38073
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18021
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240444_2_v_1_idasanutlin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55447
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-ATF5_ATF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05545
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC2912264-1471-2407-10-329.nxml--Changes_in_HMGA2_WTcells_HMGA2	Rummagene Transcription Factor Associations 2026	1.0	null
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17939
NOTCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61052
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6844
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9075
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97588749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.10809
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TONSL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41243
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE208254_4_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
amorolfine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34039
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1781
BRD-K30548577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61021
ODR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70723
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9391581-mmc5.xlsx-KLF4_K409Q_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-M45350951	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25199
BRD-K17020860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01094
BRD-A64985224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0088
PMC10042887-41419_2023_5742_MOESM4_ESM.xlsx-Table_S4-Table_S4_Overlap_genes_of_HOXB3_vs_HOXB3-_and_APC-KO_vs_APC-intact_HOXB3	Rummagene Transcription Factor Associations 2026	1.0	null
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23425
BRD-K37684893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9156
BRD-A04510218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18415
PMC7339813-Supplementary_Data2.docx-47-PRDM1_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47854067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64423
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL2_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.176
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00945
GSE240444_2_v_3_idasanutlin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83477969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53453
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161846,GSE161849_1_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74586
BRD-K11487484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06727
BRD-K61248288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41046
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6364
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.56662
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.33052
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K20736932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41911
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.09998
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11953
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
BRD-K85887470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31246
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42366
Endometrial cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.12105
GSE192860_0_v_1_trifluoperazine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95521279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20469
BRD-K04408214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61758
BRD-K14925361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02843
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242083,GSE242098_2_v_0_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236486_1_v_0_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56662
BRD-A05823365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63775
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96775
GSE196962_2_v_1_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-DOWN_in_MSC_chondrogenesis_420_1_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inner dental epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
BRD-K90697691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55728
LPIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38998
lm2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23835343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50971
GSE169571_0_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39592958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06515
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01122
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91999
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9302
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169571_5_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82359
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07484899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51687
BRD-K26976202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2567
BRD-K98140933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03599
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.126
MAPKAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75533
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2715
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-Down_in_MSC_chond_2_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62329160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36296
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal kidney morphology	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K11493601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2982
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K06863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35478
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43259
BRD-K94442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12658
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150557_1_v_0_dnmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89434
CRCGN016_MCF10A.TP53.M_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10718
MAP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52757
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54571
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
NSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17894
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40333
GSE223893_4_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165548_2_v_4_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
DBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24151
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13565
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53485
PMC11747033-Table1.xlsx-Sup_Table_S1-IFNy_LPS_TREATED_HMEC_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Endometrial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_7_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32377
GSE206516,GSE206518_2_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
GSE103003_1_v_0_zeb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41655405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20155
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84812
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5731
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34483
BRD-K37544873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87676
Nance-Horan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233049_1_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K66270896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78423
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EPRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22138
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1463
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14877
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8319
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K06058625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43537
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17809
BRD-K17209411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58388
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148657_2_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01422
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74988
PMC12611713-Table2.xlsx-Sheet_1-Training_Database_AND_Validation_Database_NOT_Diabetes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26612
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3417
BRD-K91712163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07815
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01239
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93263
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5687749-pone.0188272.s005.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_Expressed_Genes_in_Common_between_AFX_compared_to_both_Keratinocytes_and_Fibroblasts_FOXO4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210870_0_v_1_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95121261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44016
IGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60848
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7397
BRD-K22316029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.14494
BRD-K97391170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2333
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-SOX9_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86008496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07912
RAB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21832
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97435
BRD-K75331656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18371
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ABCF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58469
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.3833
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131660_1_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201251_2_v_3_coumarin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K94915822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4814
BRD-K84348716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05003
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8554
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.588379
PFKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83734
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40465
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33863
SNRPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28187
proxyphylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32922
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0555
BRD-K71139459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04895
BRD-A57457448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12737
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95932
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17713
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85295
BRD-K88962898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38717
BRD-A23980907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03514
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27314
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66502
PMC6657958-pgen.1008250.s015.xlsx-ETS1_siRNA-Unnamed_0_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.81633
BRD-K98016463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59561
BRD-K03343162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67283
CALU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19671
BRD-K56531121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0006
PURA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7317
BRD-K00191683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2042
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92367471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39503
GSE183271_4_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4786
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.04687
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
BRD-K56536241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52452
GSE174701_4_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02778838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21986
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17309
BRD-K69780027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53828
GSE169571_5_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37760996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59228
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30806
SUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9152
Buccal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
BRD-K06152379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2713
BRD-K14671528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29016
oseltamivir-phosphate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39595
ZFAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09914
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64748422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.5355
BRD-K98008739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53495
GSE160077,GSE160084_3_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Thyroid follicular epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
BRD-K38766433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11103
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85200795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80757
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00265
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05751
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.03916
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74306
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00083518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05122
BRD-K94306568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82546
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K38694430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37499
Giant cell tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
RASA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4539
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2275
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12132
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72965
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HPEC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.651
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44483161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63638
BRD-K75588273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06602
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03599766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01647
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K47599661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57357
POLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46716
BRD-K07798964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23897
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28079391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.24668
BRD-K97486995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2956
GSE219274,GSE219276_3_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CFLAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26602
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81683
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42182
SLC39A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19436
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91072
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TPM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86611
BRD-K35336753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21696
GSE174498,GSE174500_5_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45268
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186440,GSE186443_1_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68321
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00317
BRD-K81725246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46129
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38681
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A12166214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20524
Cervical intraepithelial neoplasia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52864
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22149
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.75
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46611
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K62800316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05346
BRD-K86111620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29435
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.83325
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.47126
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58099
BRD-K31870622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21946
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72807
BRD-K84077642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15459
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10985
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160077,GSE160084_2_v_0_bin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K65823297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09013
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70057
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71644
BRD-K52570793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44798
BRD-K26005379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51682
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60224
KDELR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61001
enlarged thymus	IMPC Knockout Mouse Phenotypes	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03848296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1998
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48064
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96379403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72714
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.739
ATP5PO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59853
CRCGN008_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39178
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.127
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K51654114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94506
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1063
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75018
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47441131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.38919
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02698
GSE142210_4_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9871
Buccal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K46298622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11082
BRD-K35222206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58669
GSE138938_1_v_3_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-DOWN_in_MSC_chondrogenesis_420_2_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40649636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08406
PPP1R12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69088
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55177
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5978
PMC12396377-jcb_202307079_tables1.xlsx-Fig_1C_i_-_iii_left-x_TFEB_KO_con_VS_WT_con_DOWN_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.0281
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K28107038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05088
GSE160083,GSE160084_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K36096526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40549
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61191
FTC-133 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23021
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88925664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6461
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8699
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K89806367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25899
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85741537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21859
BRD-A66025870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04355
BRD-K49698948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44069
BRD-K48756106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43915
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169571_5_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142684_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18473
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35942
BRD-A74615450	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04745
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36155
BRD-K61388138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.53566
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1569
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9374162-mmc3.xls-126_gene_details_MSC_EF_EWSZF7-Gene_name_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K66896657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32854
BRD-K77345736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54885
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NBPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9475
BRD-K46311453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48875
BRD-K95428783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19065
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18567
GSE189859,GSE189861_3_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48286
BRD-K26758344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60373
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.4828
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70995
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K65888165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09895
PRAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34612
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40855
BRD-K46599443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09791
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_5_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2241
BRD-K34297711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55301
GSE151829,GSE151831_7_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74641261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14925
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DGUOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49457
GATB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51662
TBCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59519
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Leukocyte telomere length	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6009
BRD-K71501826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9112
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A71880598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46588
Moderate-to-late spontaneous preterm birth	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.704576
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88565
BRD-K75814223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35023
EMC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73781
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3684
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.32018
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115763_3_v_1_klf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91895
GSE173873_10_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97869597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01984
MIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0719
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10483
CRCGN015_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19408
PMC9928584-41556_2022_1059_MOESM3_ESM.xlsx-Table_8-Supplementary_Table_8_ETV6-repressed_genes_defined_by_dTAG_at_72_hours_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214842_0_v_1_atf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54837
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49981566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.99297
BRD-K51363316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36072
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31547
BRD-K44626845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11305
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41003
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55461
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68985
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10708
BRD-K47113219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0666
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123861_1_v_0_sin3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91459693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15868
PMC9391581-mmc5.xlsx-WT_KLF4_vs_GFP-gene_name_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5832
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K77214780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25522
BRD-K05286676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99489
BRD-K11251396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44553
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07465
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3154
BRD-K86155080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31351
GSE217363_6_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240258_0_v_1_prmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4292
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K62320774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69944
BRD-K07431402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.11381
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6608
GSE184902_3_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82619993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70767
p3h3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9408
PMC10130768-LSA-2023-01950_TableS5.xlsx-Genes_repressed_in_Primary_PCa-BAZ2A-TAM_repressed_in_BAZ2A_KDM1A_High_primary_PCa_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-DOWN_in_MSC_chondrogenesis_420_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K24557107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12224
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0585
BRD-K35717699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06652
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24362
BRD-K96619480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73276
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24289
BRD-K85271599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46827
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71465
BRD-K84391462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41064
BRD-K70844489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1588
BRD-K61520618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56182
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K63568016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83862
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-BRCA2_393_TCF7_rep1_sorted_peak-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE242199_9_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47177
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0486
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24713
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.397896
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157960_2_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40266835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2351
GSE200430_1_v_0_sema3d_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE161800_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PI4KB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24686
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01327
abnormal thymus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60830482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04516
GSE149760_0_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197555_0_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83013
BRD-K26091803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84061
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K29713418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43138
BRD-K83775558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04609
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210476_11_v_10_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85664064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64333
AZIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27935
BRD-K87275815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55957
Amoeba	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
BRD-K88189489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24407
BRD-K91885806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03396
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48875
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44147
CRCGN014_HEPG2_3H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69855
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45335
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K68968009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95128
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246567_0_v_1_acat2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12498101-cd-24-1904_supplementary_tables_s1-s12_suppst1.xlsx-S7-Supplementary_Table_7_Human_tissue_RNA-seq_differential_analysis_for_SPOPmut_vs_SPOPwt_AA_vs_AG_and_AG_vs_GG_clone_data_DEG_set_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0153
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51293
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_2_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11168234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34564
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DEF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09837
SCRIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06761
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K10820981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65494
BRD-K06500446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05587
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49995660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0437
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
increased freezing behavior	IMPC Knockout Mouse Phenotypes	1.0	null
RPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03579
BRD-K63163033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59841
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K94629607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.665
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15189
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7745
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.76634
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55638368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09096
BRD-K25387295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23588
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.355
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34695
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242199_9_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_34_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05096562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.352
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8968
BRD-K64722080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23673
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83527041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20237
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.0401
PMC12749580-42003_2025_9274_MOESM6_ESM.xls-Supplementary_Data_3A-Supplementary_Table3A_Full_results_of_the_reverse_MR_for_significant_proteins_in_deCODE_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5047
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9206
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17061569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21808
GSE149760_0_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67817697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0855
BRD-K90429860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4322
GSE254155_1_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00487
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9257
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.99815
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3198
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K24825509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35733
BRD-K83786559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63353
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54179521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56337
BRD-K61022988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71398
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51531
BRD-K96491043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01417
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160083,GSE160084_2_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3414
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91576495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34192
FAM171B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14379
BRD-K13059597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42129
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94401439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71305
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76538
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45415
BRD-K51933590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29907
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82517280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33602
BRD-K92655427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07037
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A04975445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42615
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75702
BRD-K73176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22169
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	200.55
BRD-K75065750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37635
CRCGN015_HEPG2_48H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25305
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.13441
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.504
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0441
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10707948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46038
GSE246660_1_v_0_lmo3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76755209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39584
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.166
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	1.93404
BRD-K66889220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25922
BRD-K11990377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32655
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31298
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.149
BRD-K50600207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23555
BRD-K66735533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45069
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K67096634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2748
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.11328
HOXB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12008
GSE210093_0_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33986
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69375224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55458
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38949
MPHOSPH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.34697
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYO9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19384
BRD-K56912308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00038
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40355
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44458042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71944
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K99824630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91204
GSE238018_1_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9325
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5503541-oncotarget-08-38399-s003.docx-1-HOXA10_HOXA10	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76087207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3591
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79484
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73218
Schinzel Giedion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10959171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19567
PMC7566571-supp_075176.120_Supplemental_Tables.xlsx-Supplemental_Table_S9-Down_in_MSC_chond_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43567
BRD-K30910725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58925
BRD-K47349976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70451
PMC7608835-aba3058_Table_S5.xlsx-RING1B_EWS-FLI1_ACTIVATED-RING1B_EWSR1-FLI1_activated_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
succinylcholine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37267
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14492
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12223
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-COMMON_KD-UP_and_OE-DOWN-86_common_elements_in_kd-up_and_oe-down_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K03089783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28949
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11951866-mmc1.pdf-97-VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186440,GSE186443_3_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6665
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12116329-CTM2-15-e70302-s002.xlsx-Suppl_Table_1-Supplemental_Table_1_Top_upregulated_and_downregulated_genes_following_MSC_cytotherapy_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42126874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61829
increased fasting circulating glucose level	IMPC Knockout Mouse Phenotypes	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K53988836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55084
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21652
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18247
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38081867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05058
BRD-K76400756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76697
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	65.7766
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.012
BRD-K55453160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01207
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K78249980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11378
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K29992178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37633
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27972
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31852
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00113
BRD-K90934902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56335
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
TCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78903
DDX52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26195
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.3998
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.21297
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-R-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.87515
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PCYOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40805
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE173873_10_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66331
CRCGN012_HEPG2_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16223
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97385
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9931
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2174
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32059
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01049
Guanidinoacetate methyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4528
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40462
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.84167
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-4.00665
BARHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01478
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Downregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31377965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26897
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5217
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03562091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16126
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPSB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54063
PMC4686057-pone.0145107.s001.xlsx-PAA-CAA-Unnamed_0_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7351
BRD-K06398048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29136
BRD-K06029218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52439
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197342_1_v_0_berberine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16918
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88613983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78629
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0397
GSE172019_2_v_8_rnf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3699
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K23405268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45083
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69274755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34616
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.49295
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
BRD-K73795883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09913
GSE210476_2_v_6_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62185
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01972
BFAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0316
GSE184902_3_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6523
BRD-K05414181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48815
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE222114,GSE222115_1_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5488
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_induced_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7102
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91944762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79733