association	dataset	threshold value	standardized value
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.119
AC-30-XU83_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.484134
BRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05412
PMC5651844-41467_2017_1173_MOESM5_ESM.xlsx-Down_genes_shY2-1-Supplementary_Data_1_Down_regulated_genes_in_ShY2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pachytene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.942
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36091
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222612
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-18-GQ83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377197
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251493
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29254
MYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43123
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3853
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500238
CE-18-AP85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.362642
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
BE-90-YK54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222907
TEX261	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18675
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31161
BC-54-ON71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231989
BC-09-JG96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318557
FD-29-MM50_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.345772
AE-14-NN26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230439
GSE152699,GSE152723_3_v_2_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
spectrin-associated cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
Metaphase plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
FD-48-HZ39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284436
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.471567
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3153
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32221
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430792
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32475
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37559
JC-06-ED36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28388
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.635719
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CF-42-OS28_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253635
XA-12-UL84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296922
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.9207
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
S0-EE-Y6WJ_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26395
Pollen mother cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.791
DB-56-XL71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310285
PMC12678582-41698_2025_1153_MOESM5_ESM.xlsx-Sheet1-Common_genes_between_OVCA420-ZNF217_and_MCF7_157_965_1122_ZNF217	Rummagene Transcription Factor Associations 2026	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1303
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB-86-BE39_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262713
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23491
condensed nuclear chromosome	GO Cellular Component Annotations 2025	1.0	null
AA-99-PN83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214137
GSE211286_1_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9263655-mmc3.xlsx-ZNF436-AS1-Prediction_catRAPID_ZNF436	Rummagene Transcription Factor Associations 2026	1.0	null
CA-66-YB17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22156
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307003
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.488901
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1177
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217716
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31737
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278098
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	64.114
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.21585
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201206
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08303
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375316
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Azoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.445
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.243972
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266537
Spermatid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.842
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26466
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260917
GSE86813,GSE86814_0_v_1_atf7ip_human	RummaGEO Gene Perturbation Signatures	1.0	null
BA-92-YC70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347454
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2806
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477586
PMC10794847-mmc3.xlsx-PBRM1_KD_down-Table_S2_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_differentiation_state_Related_to_Figure_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Late recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.112
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KB-72-ID36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259309
AA-58-FJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406641
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.078
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.644437
AB-82-EP26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253179
FC-22-VC55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263504
MutLgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.344
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.535
GSE217776,GSE217829_4_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1406
BC-13-OQ01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307562
CF-24-KQ98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.510638
PMC10534007-Table_2.xlsx-S4_unique_down_MSC_V-745_elements_included_exclusively_in_VM-CUB1_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230553
AC-44-UR36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202502
Sertoli cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.501
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4127
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4172
FB-24-UT80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217275
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325233
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36306
DB-63-TM61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225414
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-30-CR11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28589
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268393
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205070_1_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PD-60-FM93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36862
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4479
FE-06-GR60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254629
AA-27-TF89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20828
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285707
AC-30-XU83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278128
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.400937
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75633
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Renal epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
Charcot-Marie-Tooth disease type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
ERCC4-ERCC1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.802
KE-37-MN32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257064
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1773
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sertoli cell-only syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
Scrotum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
EHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34832
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445524
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.482399
Zona reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.034
BA-15-VE07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216469
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03955
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30106
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.9739
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85088
MOCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08603
MutS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.041
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.1507
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3573
BD-18-MM33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.603574
GSE159678_6_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
EA-17-BY69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346496
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31534
46 XX gonadal dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
Seminiferous tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.638
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.796
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.3584
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.175
DF-00-BX35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411143
smc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.332
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428691
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.337
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273662
EE-01-FB85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.37137
MAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74249
Acrosomal vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.311
Zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
GD-82-CS38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270424
DOT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30064
Condensed nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273066
PMC3470785-NIHMS377161-supplement-3.pdf-161-SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376107
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07559
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4706
DNA repair complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.795
EB-67-WB79_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287929
PMC12754469-ab-25-0159-Supplementary-1.pdf-37-TBX18_TBX18	Rummagene Transcription Factor Associations 2026	1.0	null
AB-12-IS33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428606
CE-95-YX02_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259586
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10824
AE-13-CX28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33984
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9185
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.205783
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361086
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
Varicocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.498874
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304861
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43025
nucleus-vacuole junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
DONSON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28175
Kuru	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
DF-75-OU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394163
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423849
AD-99-SN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.436546
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE239844_1_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3872
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232583
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433492
PMC8649869-EMMM-13-e14351-s012.xlsx-Common_downregulated_elements-264_common_elements_in_siY_T_SRF_DOWN_and_siATF4_SRF_DOWN_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2686
AB-18-YN11_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.432729
Optic nerve sheath meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438342
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital hypoplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.397
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.589901
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19907
chromosome	GO Cellular Component Annotations 2025	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469279
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	120.8
Central element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.342
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283246
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34247
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03358
Klinefelter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.689
GSE144500_8_v_11_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
NANS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5803
GSE173201_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hereditary spastic paraplegia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Adrenocortical cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
Meiotic spindle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.795
GSE206270_2_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42635
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-00-YH62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252951
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
resolution of meiotic recombination intermediates	GO Biological Process Annotations 2025	1.0	null
LE-60-VC29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227222
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Foxo3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3679
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2715
HD-29-LW24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233727
Nucleolus organizer region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297242
AC-83-LN99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378598
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353712
USP6NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23233
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60087
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Synapsis initiation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.433
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5088
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fruit capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11158
GSE196117_6_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399616
Spermatogonium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.868
AA-30-BE85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262894
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1826
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.60181
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428499
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23444
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203668
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283924
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04972
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223921
BF-00-PE90_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299477
Nuclear chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.666378
Silique	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
RNASET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02572
KB-49-NF63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216872
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NB-12-ZK38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447003
Condensed chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13137
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218196
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3047
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.8712
KC-32-GO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375627
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9044
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BC-62-RZ55_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.477761
PPP2R5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0906
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6609
Stratum granulosum cerebelli	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.016
XY body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.113
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40865
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290269
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
ID-70-SM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202527
DB-56-XL71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.572752
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.493467
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.244
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76455
TAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03122
IC-72-HR20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306063
PSKH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55992
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3534
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30464
CC-18-YW57_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304849
CYB5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31773
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327385
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07936
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209286
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0348
FF-86-NH56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329154
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.399143
Twist2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8894
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.551079
AB-18-YN11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274658
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
PICALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98919
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328817
QA-14-AU91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.428892
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4988449__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85914
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.639914
DA-35-DU85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222766
MutLbeta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.813676
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394892
GSE95685_2_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YA-85-VH07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410502
PPAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50208
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZBTB44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16249
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AA-58-FJ71_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.689671
Regio orbitalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6975
ADAMTS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4789
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5308
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455111
RK-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49094
AE-19-BK71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.844569
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
RecQ family helicase-topoisomerase III complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.918
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151090_0_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.7831
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DCAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10615
Coronary artery disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
DA-17-XI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403669
GSE144484_2_v_1_mllt6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HE-16-PO98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369774
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236345
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9377
OC-40-XI13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352316
MMRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45808
BC-00-YH62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215345
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217032
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200423
FD-49-XC21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221367
GSE179002_2_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YF-00-IN39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235468
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283367
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21526
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.473199
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.348479
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3471
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394868
GSE145990_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MA-43-MR37_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291057
FF-34-KW62_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219542
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05807
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15967
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363369
Oligoasthenoteratozoospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235198
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41338
QA-34-PH05_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24843
NE-00-JZ19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268371
TE-26-XS06_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.332632
Oligospermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.421
AC-36-TL21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27795
CB-32-EI69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231178
CF-24-KQ98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338065
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.273
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0067
Male infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.371
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47899
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.551609
PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
496100663_TCx_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.33547
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19126
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE181431_0_v_1_calr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PD-60-FM93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207929
BE-42-IC00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31434
NCCIT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
MA-43-MR37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219126
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396533
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
AC-47-YZ27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214508
Alevin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
PMC11588066-pnas.2410331121.sapp.pdf-149-ZBTB1_ZBTB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329942
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4224
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.418943
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42385
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465598
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.259
RD-90-OY66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.610815
FOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80854
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64595
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EE-02-BO83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338334
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5207
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2003
Inhibin B complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1962
CD-16-KY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226156
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.253597
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4211
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3704
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.454754
BB-20-UU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276665
TWIST1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6793
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56519
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319686
FE-64-KC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240026
BC-56-CP81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268199
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Meiotic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.321
AD-86-OB87_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.384834
ECE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28895
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1209
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46436
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313543
GSE186460_0_v_2_baricitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.244
Primary ovarian insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.874
AC-36-TL21_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337587
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
Pollen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.389
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19222
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Holliday junction resolvase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
PC-62-AQ92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273379
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2751
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03002
UC-58-DM11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430293
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247085
Lateral element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.355
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.577159
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Transverse filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.686
Vas deferens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.481
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1871
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296904
PMC9314667-Table_1.xlsx-Regulons-IRF7_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251735
UBE4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22593
Spermatogenic failure 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
PMC12152148-41420_2025_2541_MOESM3_ESM.xlsx-AR-IP-DHT_peak-gene-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CYP2R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58772
AC-36-TL21_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58674
ED-71-GA72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.31159
AE-32-DP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.438726
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18546
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9092
FAM53C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1434
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224593
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1361
ZNF83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1046
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3767
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6214
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282422
GSE182680,GSE182683_10_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr9_111805480_T_C_b38	GTEx eQTL 2025	1.0	2.25124
BD-48-ZT65_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24884
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
DC-78-CM38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219815
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.097
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_9_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-24-LQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347374
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.544
OA-54-FL10_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252324
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.629
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314656
LD-69-ZV56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314458
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7866
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35235
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94823
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.282629
Congenital bilateral absence of vas deferens	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13811
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HE-80-BQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27891
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8767
CE-03-YQ91_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.352408
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.009
SUM-1315MO2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.846
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
AF-30-GH67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.53786
PMC8497275-41388_2021_1985_MOESM9_ESM.xlsx-ER_targets_ER-SRC3-RAC1_sites-Nearest_Ensembl_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
AF-30-GH67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387313
PMC9170821-JCMM-26-3183-s001.xlsx-Mic_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2556
FECH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81011
CLOCK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2823
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Aplastic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7783
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29732
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196117_1_v_8_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AA-99-HO76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292632
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.334993
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19089
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02734
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.7707
AA-56-JY17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217331
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.293174
NC-27-AD53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214006
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07061
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23236
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Doxycycline (monohydrate)_NCI-H2030	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00552911
CA-75-HA22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.61875
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375749
GSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42975
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1196
PMC9992472-41467_2023_36735_MOESM5_ESM.xlsx-SOX11_OE_9h_in_SH-EP-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16361
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211923
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430046
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16272
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.738915
ONECUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18806
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09718
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4429
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24932
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280933
GSE88819_6_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7344
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380067
condensed chromosome	GO Cellular Component Annotations 2025	1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289531
GSE231648_0_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PD-05-HV36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236304
BD-96-HO33_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341501
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.624534
CF-61-EH59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208605
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234403
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.541
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17271
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4016
KA-75-LP02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249458
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
Monopolin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1764
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15717
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19107
Spermatogenic failure 11	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.802
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.337269
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15494
CDCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20969
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.505061
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390163
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287929
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.974945
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AD-51-LE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237972
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84307
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-97-BI36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208353
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
synaptonemal complex assembly	GO Biological Process Annotations 2025	1.0	null
DA-83-IZ87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251907
LA-44-KW22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274167
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RASGRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09459
JD-87-KA71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495392
AD-29-IG16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.36885
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.276508
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244144
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7208
Antipodal site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06456
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2758
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204277
Charcot-Marie-Tooth disease type 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
trans-Golgi network membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3474
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4122
LF-94-HB11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285751
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230353
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nuclear chromosome	GO Cellular Component Annotations 2025	1.0	null
Nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.163
Fanconi anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
DD-54-MA35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225412
Pairing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.7808
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
KD-31-TU05_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371299
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	118.129
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.4443
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33569
CA-25-LR28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371092
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247607
GF-37-MB64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355277
QB-88-PG52_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224666
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3381
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-14-CG34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292394
AB-30-CR11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218546
IB-56-JN40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.405359
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420417
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209831
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77508
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8649
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08521
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_InDel-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
SLC7A6OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1276
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28074
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.9831
FE-82-WB22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406026
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.425275
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Semen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.788
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pelvic varices	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
CE-69-HJ13_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216147
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453607
Primary spermatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5078
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239432
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1361
Cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.462
FD-69-CC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210764
Testicular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.44497
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94472
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37798
Varicose veins	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
MA-31-VM30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219611
GSE135352_0_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.375657
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14396
BB-86-BE19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226068
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.542
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.342713
Amenorrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232542
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.244
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42548
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246115
av3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495138
BB-86-BE39_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219902
GSE133516_0_v_2_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4107
CYBC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16003
HE-16-PO98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224734
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256224
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TBC1D23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0195
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.534
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HAUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22116
GAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21705
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07227
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.14927
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220411
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CC-50-FK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.367231
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.8437
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224344
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.591
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.359
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_chimp_DRSG_higherRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.469718
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34157
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60235
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Vegetative cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.787
CB-46-FO63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.562899
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73951
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23253
Mitotic spindle microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
GSE193258,GSE193259_9_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.509
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230688
cellular component assembly	GO Biological Process Annotations 2025	1.0	null
PMC4695334-mmc3.xls-HCC_SMAD3_DNA_Me-Unnamed_2_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1848
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7201
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392379
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.012
BE-31-XV38_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.30917
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157894_1_v_3_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
DHRS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68864
OE-75-WF43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.249244
AA-52-JS03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.644849
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62124
RPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30014
Meiotic prophase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
AC-28-RT00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227092
DE-30-UR76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213642
KB-49-NF63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223613
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.532
Endonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.095
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.398777
BD-69-XG81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.481654
Plant bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
Orchitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3021
ATP6V1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
Meiotic cohesin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.683
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63199
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365658
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0582
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
JF-62-LU77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340552
BA-69-TQ80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297731
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5738
GSE138818_1_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
EF-33-QP63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200718
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4064
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Testicular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.502117
FANCM-MHF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.967
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8302
GSE135352_6_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA-48-JF51_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341691
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
MFSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19121
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HB-54-ZC59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209241
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38369
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.711
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39897
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0785
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37791
PMC10800016-table_s5_20230913_ddad186.xlsx-FvsC_-_DUX4_I-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
RPL10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23163
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15861
PMC5225790__F11	PFOCR Pathway Figure Associations 2024	1.0	null
BE-31-XV38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463689
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MutSgamma complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.738
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32911
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7259
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.81
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.266212
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20169
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280248
Primary ovarian insufficiency	WikiPathways Pathways 2024	1.0	null
Intraorbital meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50929
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480056
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43891
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268802
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
single-stranded DNA binding	GO Molecular Function Annotations 2025	1.0	null
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335957
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58552
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
CF-24-KQ98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457957
BA-10-WH12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48493
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03086
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100585_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17827
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.696
Spermatogenic failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.194
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
CC-68-YZ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.285084
GSE138818_2_v_0_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299941
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ASB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42224
homologous chromosome pairing at meiosis	GO Biological Process Annotations 2025	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325721
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12186
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.467278
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437132
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9139
AB-18-YN11_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.452428
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
UE-58-EW15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202173
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.244
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2389
HE-80-BQ08_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235988
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10131
chr9_111688828_T_TG_b38	GTEx eQTL 2025	1.0	3.04811
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9389
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.8375
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314904
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445435
AC-28-RT00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270177
AMER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01568
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5824
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
Mre11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.178
Cryptorchidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
SD-82-GT69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213489
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.5925
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3033
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11136
AA-70-DH87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224062
AD-86-OB87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327524
Early recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.76
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83147
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM4_ESM.xlsx-sheet_1-Supplementary_Data_1_Down_regulated_genes_in_YEATS2_KD_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DHPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02042
BD-73-TX58_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.329664
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36467
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VAMP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98842
DDX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5935
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84585
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.355
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2856
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CD-20-MH57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24613
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.724
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0766
JE-72-KV75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.209067
Zona glomerulosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.2318
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	78.8469
GSE185953_2_v_0_tlr3_human	RummaGEO Gene Perturbation Signatures	1.0	null
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.41931
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13329
NCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33976
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00451
synaptonemal complex organization	GO Biological Process Annotations 2025	1.0	null
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256624
DB-07-WB29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278385
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1292
PMC9539848-PATH-257-579-s008.xlsx-NCOA2_vs_NCOA2-ctrl-geneSymbol_NCOA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE222829,GSE223009_0_v_1_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxo1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1494
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.321814
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
atf1-pcr1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
BB-44-SX65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25732
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218196
GA-28-SS67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.587003
ri1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
MD-86-UW46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295115
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13172
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118490_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NA-30-HS87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376781
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.422
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18399
PMC4523944-DataSheet1.PDF-12-ZNF497_ZNF497	Rummagene Transcription Factor Associations 2026	1.0	null
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309773
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GD-69-KC91_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214941
ZNF337	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27952
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05491
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tetrad of microspores	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.537
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.420094
Epsilon DNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
EB-33-ZP53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291475
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411754
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45316
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.347434
AD-86-OB87_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21938
BB-11-JI42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213456
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9941
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-DEG_MDDC_C91-PL_LPS_vs_MDDC_Jurkat_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.277114
46,XX sex reversal	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
DDAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10289
Fanconi anaemia nuclear complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.172
JD-62-HR05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34845
PMC8571097-41588_2021_941_MOESM3_ESM.xlsx-Supplementary_Table_2-Supplementary_Table_2_List_of_KMT2A_fusion_oncoprotein_target_genes_in_each_sample_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189599,GSE196004_0_v_1_bend2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.522111
GB-46-CK08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.371331
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226151
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02685
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15492
DT-40 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793