association	dataset	threshold value	standardized value
abnormal diencephalon morphology	MPO Gene-Phenotype Associations	1.0	null
Ethanolamine ammonia-lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.701
CCDC47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51813
Central nervous system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
brain	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3133	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.229032
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.376
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29895
autism	HPO Gene-Disease Associations	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Erectile Dysfunction	DisGeNET Gene-Disease Associations	1.0	null
BRD-K18173053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07422
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133857
ABL1_knockdown_137_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78936
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838723
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06542
CRCGN011_HEPG2_24H:F24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03425
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27161
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sympodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
PMC10383317__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.855
SNU5	DepMap CRISPR Gene Dependency	1.0	3.22748
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52507
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.704
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
subthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0118
Embryo Loss	CTD Gene-Disease Associations	1.0	1.12838
signal	GeneRIF Biological Term Annotations	1.0	null
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3428
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044311
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.552
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5661
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96723
BRD-K07706477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09743
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75252
Perturb_15060_OE_Trp53_SRP345823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.64622
Hyperphagia	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-3176	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K38917645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10841
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25102
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tube development	GO Biological Process Annotations 2015	1.0	null
Forelimb muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64609
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79221878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63611
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96219
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.628
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10468
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831053
GRM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04964
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSK3B_knockdown_204_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.36873
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00318
full cheeks	HPO Gene-Disease Associations	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29286
ARFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13016
ADRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07334
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.575
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.0619
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
Central diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
KDM4C_natural variation_GSE41040_590_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.083381
altered	GeneRIF Biological Term Annotations	1.0	null
BRD-K13110695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.003
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CORL105	DepMap CRISPR Gene Dependency	1.0	2.96101
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875965
short stature	HPO Gene-Disease Associations	1.0	null
Axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.693
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04173
variation	GeneRIF Biological Term Annotations	1.0	null
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32036
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21688
regulation of transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
terminal nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12311
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39872
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39964
ureteric bud development	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3064-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K04143388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53027
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15405
Notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56027
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905175
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8158
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19203549	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60061
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989428
BRD-K04426746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34289
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01646
Corpus allatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.578
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48154
PMC10800016-table_s5_20230913_ddad186.xlsx-FvsC_-_DUX4_I-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
ITGA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12587
distinguishing	GeneRIF Biological Term Annotations	1.0	null
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE158834_11_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-660	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24548
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21915
macrotia	HPO Gene-Disease Associations	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26234
SuperiorCervicalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
some	GeneRIF Biological Term Annotations	1.0	null
OVKATE	CCLE Cell Line Gene Expression Profiles	1.0	3.40792
arnt2	GeneRIF Biological Term Annotations	1.0	null
semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415434
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
morphological abnormality of the central nervous system	HPO Gene-Disease Associations	1.0	null
Malignant Tumor Of Cervix	DisGeNET Gene-Disease Associations	1.0	null
RNF2-27304074-CHIP-SEQ-NSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1418
Neuron projection branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040575
organelle envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.49499
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.907
Acute Myeloid Leukemia_LAML_TCGA-AB-2991-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99636
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.225586
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.04415
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.436
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04087396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32738
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3558
BRD-K65416438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14674
variants	GeneRIF Biological Term Annotations	1.0	null
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07988
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4375971__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
Lateral tuberal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.291898
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nystagmus	HPO Gene-Disease Associations	1.0	null
hyperphagic	GeneRIF Biological Term Annotations	1.0	null
Impaired Glucose Tolerance	DisGeNET Gene-Phenotype Associations	1.0	null
locus	GeneRIF Biological Term Annotations	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045893
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12266
abnormal glucose homeostasis	MPO Gene-Phenotype Associations	1.0	null
homeostasis	GeneRIF Biological Term Annotations	1.0	null
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.952
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infralimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90863
BRD-K30173420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29222
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16625
SLC35A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23597
ESS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53471
Sarcoma_SARC_TCGA-WK-A8XT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100653_PCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.31833
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0602
BRD-K89423851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42909
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Sexual health disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Hypoactive sexual desire disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
adiposity	GeneRIF Biological Term Annotations	1.0	null
Schaaf-Yang syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
LTBR_INHIBITION - 1 Day_GDS2004_733_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-A95239561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18953
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
hsa-miR-4490	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_1202_KO_Sp1/Zbtb7a/Klf16_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.27813
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KDM4C_natural variation_GSE41040_588_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905709
haploinsufficiency	GeneRIF Biological Term Annotations	1.0	null
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.256
abnormal susceptibility to weight gain	MPO Gene-Phenotype Associations	1.0	null
Organelle inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.932
Low Grade Squamous Intraepithelial Neoplasia	DisGeNET Gene-Disease Associations	1.0	null
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956264
dopaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.453355
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50213
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8483
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.207
Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33053
medial basal reticular formation of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09862
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14655
RER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58459
BLOC1S6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91553
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
95T1000	DepMap CRISPR Gene Dependency	1.0	2.53973
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	1.38272
BRD-K08751619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04237
LGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49591
MTPAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77661
hyperactivity	HPO Gene-Disease Associations	1.0	null
homolog	GeneRIF Biological Term Annotations	1.0	null
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98643
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6107
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92717
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45786
hsa-miR-525-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28792
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4375
endocrine	GeneRIF Biological Term Annotations	1.0	null
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7498
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47112
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNA binding	GO Molecular Function Annotations 2023	1.0	null
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5672-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.605
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.959449
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPC-N	GDSC Cell Line Gene Expression Profiles	1.0	2.20852
KMRC3	DepMap CRISPR Gene Dependency	1.0	14.4326
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal erythropoiesis	MPO Gene-Phenotype Associations	1.0	null
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61598
Nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.532
increased body weight	MPO Gene-Phenotype Associations	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14955
APEH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26914
abnormal diencephalon morphology	MGI Mouse Phenotype Associations 2023	1.0	null
LIVF001-015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17451
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08039
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869097
Subesophageal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989428
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11075
hsa-miR-4318	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ureteric bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.816
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99894
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862931
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35068
DOV13	DepMap CRISPR Gene Dependency	1.0	2.16227
contribution	GeneRIF Biological Term Annotations	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.998283
ATP6V1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12517
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.08126
FKBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61129
PMC7674228__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.624
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-52-PRDM13_PRDM13	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47237224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.229
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03149
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.97403
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44627
PMC3089461-supp_gkq1313_nar-02376-m-2010-File010.xls-Table_S6-TF_targets_of_E2F4_from_our_ChIP-seq_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
Ethylnitrosourea	CTD Gene-Chemical Interactions	1.0	null
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58495
hypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.242945
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.128
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.17168
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76862
FZD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80795
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42031
Subparafascicular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43861
abnormal circulating hormone level	MPO Gene-Phenotype Associations	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61849
Smith-Magenis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
Obesity	CTD Gene-Disease Associations	1.0	2.88009
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33086
MYC	ENCODE Transcription Factor Targets	1.0	null
PBX1	ChEA Transcription Factor Targets	1.0	null
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26165
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.078527
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44545
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53244
Bam protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
BRD-K15523383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5838
round face	HPO Gene-Disease Associations	1.0	null
regulation of rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19178
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.839182
pituitary gland hypoplasia	MPO Gene-Phenotype Associations	1.0	null
Hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.058
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27483
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6672
BRD-K03070790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54325
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41439
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.698284
CENPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87922
nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.31712
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904413
NCIH510	DepMap CRISPR Gene Dependency	1.0	4.12236
statistical	GeneRIF Biological Term Annotations	1.0	null
TUBB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32027
GSE184892_0_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
MYC	ChEA Transcription Factor Targets	1.0	null
BRD-K87539610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01518
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-606	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ZNF106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
GTF2H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38118
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.824
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33966
cytoskeletal calyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.501476
vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358174
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93168
HBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58887
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.145
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05884
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.987
sim2	GeneRIF Biological Term Annotations	1.0	null
Polytene chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
FAM83F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53553
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16971
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.476027
abnormal glycosylated hemoglobin level	MPO Gene-Phenotype Associations	1.0	null
embryonic brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225144
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
Cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36263
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88093
BRD-K48213854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50041
Perturb_15702_KD_AGE_SRP353924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.8183
PMC10313373-jci-133-164637-s072.pdf-39-STAT5B_STAT5B	Rummagene Transcription Factor Associations 2026	1.0	null
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04382
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44205
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59733
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CARD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16943
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01322
EIF1AD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13206
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2186
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01441
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11657
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
abnormal brown adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
18637760-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Multiple synapse bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.459203
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of DNA-templated transcription	GO Biological Process Annotations 2025	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	3.12257
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45006
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81752
Iris disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
H2810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447961
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
ERBB2_druginhibition_8_GDS2139	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.54493
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
Epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26797
bcan	GeneRIF Biological Term Annotations	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934746
GSE180525,GSE180528_2_v_3_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal paraventricular hypothalamic nucleus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.492
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K12909905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.386
Blastoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.869
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09894
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055462
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KARPAS-299	GDSC Cell Line Gene Expression Profiles	1.0	1.46763
BRD-K52423731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64145
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.350243
CRCGN017_MCF10A.WT.HP_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3899
medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267446
CRCGN015_MCF10A.WT.HP_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22617
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67618
BRD-K01311880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6122
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.943706
brachydactyly syndrome	HPO Gene-Disease Associations	1.0	null
increased glycosylated hemoglobin level	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the skull	HPO Gene-Disease Associations	1.0	null
pyramidal cells of caudal CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30361
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pima	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCV_8week-No IFN-a_None_GSE37715	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.9738
Perturb_15301_KO_Tet1/Tet2/Tet3_SRP318893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.7825
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79165
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Inferior mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87781745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06209
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5064
GSE138741,GSE138743_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12586484-41598_2025_22484_MOESM2_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_DEGs_in_ATOH8-depleted_EVT_ATOH8	Rummagene Transcription Factor Associations 2026	1.0	null
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42459
neoplasm of head and neck	GWASdb SNP-Phenotype Associations	1.0	0.246166
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5256
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851391
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98316
heterocycle biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC44A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27022
IGFLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7619
BRD-K43186783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35686
Brain_CT2_Splat 414	HuBMAP ASCT+B Annotations	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
Congenital Epicanthus	DisGeNET Gene-Disease Associations	1.0	null
BNIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2349
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.6791
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
prader-willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.30663
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
abnormal urine glucose level	MPO Gene-Phenotype Associations	1.0	null
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
Kyphosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Byzanthine Arch Palate	DisGeNET Gene-Disease Associations	1.0	null
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.709
Tritocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
energy	GeneRIF Biological Term Annotations	1.0	null
HDLM2	CCLE Cell Line Gene Expression Profiles	1.0	1.53492
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM88	DepMap CRISPR Gene Dependency	1.0	3.00075
PMC2952980__F1	PFOCR Pathway Figure Associations 2024	1.0	null
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98647
ARNT	ChEA Transcription Factor Targets	1.0	null
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0855
BL70	CCLE Cell Line Gene Expression Profiles	1.0	1.57534
Brain_CT2_Splat 413	HuBMAP ASCT+B Annotations	1.0	null
BRD-K35789946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00669
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
SLC7A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88862
ZNF550	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28461
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4059
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45081
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109673
BRD-K87205390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69699
sim1sim2	GeneRIF Biological Term Annotations	1.0	null
M059K	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84124
LDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.00458
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
DDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67607
ZNF248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5819
TE-671 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268137
EMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30702
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ALX1_ALX1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3470785-NIHMS377161-supplement-14.pdf-542-MESP2_MESP2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7846764-41598_2021_81773_MOESM3_ESM.xlsx-b-Heart_AA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
AsPC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62048
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01118
SUDHL8	CCLE Cell Line Gene CNV Profiles	1.0	2.18173
GSE184087_0_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
Axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.902
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX11_01_213	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.86651
Morbid obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.728
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95482
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6944
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
BRD-K06418332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15617
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8758
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0242
BRD-K15269548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10537
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37761
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.841479
Laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.589
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06434
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-323-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
transcription, dna-templated	GO Biological Process Annotations 2015	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12494973-41467_2025_63880_MOESM1_ESM.pdf-93-NEUROG3_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41114
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
SENP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0266
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11388
hsa-miR-4277	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05383
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
PMC7495669__F5	PFOCR Pathway Figure Associations 2024	1.0	null
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21064
perilemniscal isthmic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29332
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35939
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932929
Prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
FLOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43714
HNRNPLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21709
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53034
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03901
Bulimia nervosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
PTGES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97019
SW1710	GDSC Cell Line Gene Expression Profiles	1.0	1.58289
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.757
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124181
PMC12902236-mmc11.pdf-7-HLF_HLF	Rummagene Transcription Factor Associations 2026	1.0	null
CAOV4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50405
diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.320454
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUCO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82469
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.026
COLO-800	COSMIC Cell Line Gene Mutation Profiles	1.0	null
growth abnormality	HPO Gene-Disease Associations	1.0	null
transgenic	GeneRIF Biological Term Annotations	1.0	null
Albright's hereditary osteodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.06
sequence-specific dna binding transcription factor activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K64469421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0505
ILF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76655
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
Internal iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.399
NSUN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.777
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43572
SK-N-DZ	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43594
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978958
hsa-miR-4482	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.182957
severe	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.535
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25084
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.56267
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25353
obesity	GeneRIF Biological Term Annotations	1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the teeth	HPO Gene-Disease Associations	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
PMC4340386__F1	PFOCR Pathway Figure Associations 2024	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
obesity	GWASdb SNP-Disease Associations	1.0	0.793562
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV504	CCLE Cell Line Gene Expression Profiles	1.0	1.96354
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27152
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69158240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00629
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.16593
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41254
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
BRD-K07009788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29686
abnormal brown adipose tissue morphology	MGI Mouse Phenotype Associations 2023	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.432618
TBP	ENCODE Transcription Factor Targets	1.0	null
MC116	CCLE Cell Line Gene Expression Profiles	1.0	1.3749
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
clinodactyly	HPO Gene-Disease Associations	1.0	null
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K76485827	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69492
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
nervous system development	GO Biological Process Annotations 2015	1.0	null
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ovarian Failure, Premature	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cervical Cancer	DisGeNET Gene-Disease Associations	1.0	null
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Superior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
BRD-K32582260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01269
PMC3584306__F3	PFOCR Pathway Figure Associations 2023	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
Condensed chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.267
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
methylation	GeneRIF Biological Term Annotations	1.0	null
GSE134029_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19886
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.558
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenal gland hyperfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K20028052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7152
Femoral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.637
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
increased circulating leptin level	MPO Gene-Phenotype Associations	1.0	null
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86324
KASUMI2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32053
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869097
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134029_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
18221536-Table1	GeneSigDB Published Gene Signatures	1.0	null
PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-138	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.635921
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
KMS34	DepMap CRISPR Gene Dependency	1.0	2.26841
Retrosplenial area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3813
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88534
MOGGCCM	CCLE Cell Line Gene Expression Profiles	1.0	1.60672
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02469
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11437
CRCGN014_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5151
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041578
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.589
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastric fundus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
dimerization	GeneRIF Biological Term Annotations	1.0	null
phenotypic	GeneRIF Biological Term Annotations	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
CEBPE	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7439
PMC11530573-41467_2024_53613_MOESM1_ESM.pdf-6-GLI1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.523
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.67225
GSE247764_4_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Larval brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15981
BRD-K36952018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05167
Clonel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
overnutrition	GWASdb SNP-Disease Associations	1.0	0.453937
BRD-K36111748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19449
characterized	GeneRIF Biological Term Annotations	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16737
MALME3M	DepMap CRISPR Gene Dependency	1.0	4.24786
Dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
NFE2L2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49481
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1547
19377508-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
INF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20415
hyperglycemia	MPO Gene-Phenotype Associations	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2132
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Microcephaly	DisGeNET Gene-Disease Associations	1.0	null
t59-kidney_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.70263
Primary motor area, Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03747
Hyperglycemia, Postprandial	DisGeNET Gene-Phenotype Associations	1.0	null
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.307
Medial amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
HBQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09713
squamous cell carcinoma	GWASdb SNP-Disease Associations	1.0	0.618776
BRD-K95573463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1345
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66619
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07891
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33868
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.945
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01512
TECPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14346
Arcuate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.59
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.06548
USP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52277
NKX6-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76716
pou4f1	GeneRIF Biological Term Annotations	1.0	null
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BBS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56601
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76369
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256234
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64611
increased white adipose tissue amount	MGI Mouse Phenotype Associations 2023	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16754
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01825
BRD-K79732056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00197
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06094529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29204
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2186
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.758
obesity, severe	OMIM Gene-Disease Associations	1.0	null
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
ZNF474	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18217
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Supplementary_Table_7_Transcription_factors_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61975
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72456
abnormality of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.386905
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
foregut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214202
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JE-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of transcription by RNA polymerase II	GO Biological Process Annotations 2025	1.0	null
Cytoplasmic ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
individuals	GeneRIF Biological Term Annotations	1.0	null
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77299
ITGB1BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99918
20436685-ST4-2	GeneSigDB Published Gene Signatures	1.0	null
Cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
SMYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34159
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
TAS2R5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88722
HIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31477
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25353
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal location of ears	HPO Gene-Disease Associations	1.0	null
regulation of rna metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_15061_OE_Trp53_SRP345823	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.76888
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5467-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Attention Deficit Disorder	DisGeNET Gene-Disease Associations	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.308867
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94X-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gait speed in old age	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
JMSU1	CCLE Cell Line Gene CNV Profiles	1.0	2.62089
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
developmental	GAD High Level Gene-Disease Associations	1.0	0.293278
various	GeneRIF Biological Term Annotations	1.0	null
congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142627
GSE184087_4_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55568
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Nearest_Ensembl_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97741
Syndromic X-linked intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92455
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	1.28531
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35504
MED23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42893
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mouth disease	GWASdb SNP-Disease Associations	1.0	0.618776
HCC202	CCLE Cell Line Gene CNV Profiles	1.0	2.08506
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.713
endocrine/exocrine gland phenotype	MPO Gene-Phenotype Associations	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9915
nucleic acid binding transcription factor activity	GO Molecular Function Annotations 2015	1.0	null
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.242217
abnormal axial skeleton morphology	HPO Gene-Disease Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.052303
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1059
superficial stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10022
PMC5644891__F1	PFOCR Pathway Figure Associations 2023	1.0	null
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35214
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87758
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.394508
within	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
Semitendinosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.623
intracellular part	GO Cellular Component Annotations 2015	1.0	null
CDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61273
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5567-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
VSNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27572
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29134
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52069
abnormal circulating leptin level	MPO Gene-Phenotype Associations	1.0	null
follow	GeneRIF Biological Term Annotations	1.0	null
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40852
mesonephric tubule development	GO Biological Process Annotations 2015	1.0	null
neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03653
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
Scoliosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60519
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8678
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50249
BRD-K37331547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02097
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23704
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.966
HEC1B	CCLE Cell Line Gene Expression Profiles	1.0	2.04741
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
hsa-miR-4697-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
abnormal renal/urinary system physiology	MPO Gene-Phenotype Associations	1.0	null
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.847
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
DLL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11717
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100348_TCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.96491
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
hsa-miR-1910	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Peripheral primitive neuroectodermal tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
FOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13935
Neurociticism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
increased brown adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
abnormality of the pinna	HPO Gene-Disease Associations	1.0	null
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301039
NFE2L2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUMO-targeted ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.275
neoplasm of the pancreas	GWASdb SNP-Phenotype Associations	1.0	0.675718
BRD-K01716842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17885
VN1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73595
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
hsa-miR-3182	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
binding	GO Molecular Function Annotations 2015	1.0	null
pancreatic neoplasms	GAD Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR2C2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19271
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06578
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1809
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92851
Hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.246
PMC7495669__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pancreatic adenocarcinoma	GWASdb SNP-Phenotype Associations	1.0	0.675718
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33903
used	GeneRIF Biological Term Annotations	1.0	null
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.562454
Inferior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.872
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
SP2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.623
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35331
Perturb_1216_KO_Klf16/Zfp580_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ARNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92529
BRD-K93866368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06427
REST	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.6033
french	GeneRIF Biological Term Annotations	1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.03345
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
all	HPO Gene-Disease Associations	1.0	null
Prediabetes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
H2BW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38749
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28775
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90463
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06683
BRD-K18352607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17534
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54031
BRD-K31820800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1528
DEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73116
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
LHX1_KO_GDS2748_298_mouse_embryonic renal vesicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pseudohypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.006
Prostate	GTEx Tissue Gene Expression Profiles 2023	1.0	3.18972
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UBAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89016
MIEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89397
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059073
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31177
small pituitary gland	MPO Gene-Phenotype Associations	1.0	null
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXO1-25302145-T-LYMPHOCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Methyl accepting chemotaxis protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.216
mantle zone of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71657
Anammoxosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22286
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58439
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
Ciliopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.214
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01414
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.91548
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RL952	CCLE Cell Line Gene CNV Profiles	-1.0	-2.56533
HEC1A	CCLE Cell Line Gene Expression Profiles	1.0	2.65492
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67265
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cohen syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.948
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6296
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68363
abnormal adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31232
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896834
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16249
BRD-K50287215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55819
BRD-K20053005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69636
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.00847
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44479
mantle zone of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03257
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040962
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04497
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06867
Axillary bud meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.524771
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633144
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.77
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58258
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Misalignment Of Teeth	DisGeNET Gene-Phenotype Associations	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
BRD-K12119989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70366
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.960503
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of the lateral lemniscus, horizontal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16914
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20401
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.91414
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
cautiously	GeneRIF Biological Term Annotations	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.743
BRD-K07035171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75328
Chromatin	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00952
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.887
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83276
disease	GWASdb SNP-Disease Associations	1.0	0.044537
abnormal neuroendocrine gland morphology	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
18559498-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
r1 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10082
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08721
SIK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02479
CMK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K93373675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67524
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46686
H3K9me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.04415
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ntera2cloned1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
Complete Trisomy 21 Syndrome	DisGeNET Gene-Disease Associations	1.0	null
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
decreased apoptosis	MGI Mouse Phenotype Associations 2023	1.0	null
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.621
BRD-K04695993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17177
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33151
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79189
RB_P130_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846474
MERO48A	DepMap CRISPR Gene Dependency	1.0	2.92859
abnormal glucose homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43481
BRD-K07826724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09737
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110248_1_v_6_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
organic substance biosynthetic process	GO Biological Process Annotations 2015	1.0	null
abnormality of the midface	HPO Gene-Disease Associations	1.0	null
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.860897
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36161
Cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.092
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77753
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09601
Macrotia	DisGeNET Gene-Disease Associations	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
Esotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
Presynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.887
abnormality of refraction	HPO Gene-Disease Associations	1.0	null
Neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.193
ORAI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58996
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.19295
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867923
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060098
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67298
BRD-K13196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67445
16611997-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.05276
Left nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27661
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14719
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41025
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60036
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848767
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.055571
BRD-K72609445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59354
SUMO activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
increased circulating leptin level	MGI Mouse Phenotype Associations 2023	1.0	null
H3K27me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96034
zardaverine-7347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW1710	CCLE Cell Line Gene Expression Profiles	1.0	1.65591
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-indep_8dpt-SYMBOL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-587	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Aristotles lantern	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.445672
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.098
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
BRD-K94728263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05275
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34894
hsa-miR-4790-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Lung adenocarcinoma_LUAD_TCGA-97-7553-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16554464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48485
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851391
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14601
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41875112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37388
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092749
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
abnormal neuroendocrine cell morphology	MPO Gene-Phenotype Associations	1.0	null
decreased apoptosis	MPO Gene-Phenotype Associations	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLVL	DepMap CRISPR Gene Dependency	1.0	3.39656
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01441
RABEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98313
abnormal circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.588431
Congenital Fusion Of Ribs	DisGeNET Gene-Disease Associations	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9073
BRD-K88504000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3267
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
SSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65482
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.34562
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28127
BRD-K01757377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39783
16611997-Table2	GeneSigDB Published Gene Signatures	1.0	null
PHC1-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NFU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46613
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6371
Basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.223
KLF4-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
regulation of macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PDHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41955
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
Temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.186
PMC7793767-Table_2.docx-1-Downregulated_genes_in_the_pancreas_of_AA_vs_controls_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
HNRNPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15832
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215653
increased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
carcinoma	GWASdb SNP-Disease Associations	1.0	0.618776
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94465
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34283
BRD-A73590800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33221
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047054
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231482
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77522
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848181
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52695
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
periventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.757845
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4981
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the cheeks	HPO Gene-Disease Associations	1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-1.93484
Retinitis pigmentosa 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.599
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.751645
Basal telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993704
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
increased circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.080308
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34667
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20737
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63099
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	1.0	1.009
BRD-K24663282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07087
PMC10951899-mmc1.pdf-7-ZNF804A_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23488
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-indep_8dpt-ENSEMBL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
GSE151364,GSE151366_1_v_2_taf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31319
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
increased white adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
ENTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96479
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28596340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2483
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6565
abnormal energy homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
Lateral entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.094
polyphagia	MPO Gene-Phenotype Associations	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.01663
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinal macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70024
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Impulse control disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.205916
changes	GeneRIF Biological Term Annotations	1.0	null
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.45
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM21	Hub Proteins Protein-Protein Interactions	1.0	null
anterior pretectal nucleus, ventral core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14463
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32053
superficial stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30115
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083382
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3889
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6957
SLC5A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38869
BRD-K46737746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01265
SLC30A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85873
abnormal cell death	MPO Gene-Phenotype Associations	1.0	null
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22877
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.169184
eeg abnormality	HPO Gene-Disease Associations	1.0	null
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46289
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85424
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Chromosomal region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.242
Creatinine Measurement, Serum (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58682
Perturb_10302_KO_Col4a3_SRP048893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.4698
Adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.522
Leaf disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20108
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55009
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.997217
BRD-K07396550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56909
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.031
IFITM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6632
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0917
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peduncular paraventricular area of PHyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03224
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.914065
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12253
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920333
BRD-K13719101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52809
DHDDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83184
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Craniopharyngioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.556
Prostomium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2723
LRP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97296
NQO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29608
TMEM69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57438
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4462
mitochondrion	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.336996
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18236
intermediate part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32622
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11966
normal	GeneRIF Biological Term Annotations	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
PMC4375971__F1	PFOCR Pathway Figure Associations 2024	1.0	null
ABCB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90157
abnormal nervous system tract morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
ARMCX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51071
BRD-K09819684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11748
BRD-A12166214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06099
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76344
OCIC4P	DepMap CRISPR Gene Dependency	1.0	2.91723
SKMEL5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.0183
transgene	GeneRIF Biological Term Annotations	1.0	null
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Internal capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.44777
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.118
utr	GeneRIF Biological Term Annotations	1.0	null
Corticospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
artery disease	GWASdb SNP-Disease Associations	1.0	0.101104
ASH2L	ChEA Transcription Factor Targets	1.0	null
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047468
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
intracranial aneurysm	GWASdb SNP-Disease Associations	1.0	0.603294
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Retrosplenial area, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1798
FGF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23691
Pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
Full Cheeks	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55577
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
ZDHHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55633
SAT	DepMap CRISPR Gene Dependency	1.0	2.13958
Perturb_4418_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12554
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65865
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.084
mediated	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
myopia	HPO Gene-Disease Associations	1.0	null
MNX1-26342078-MIN6-4N-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11791
Nucleolar ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
features	GeneRIF Biological Term Annotations	1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92851
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25332
epicanthus	HPO Gene-Disease Associations	1.0	null
Helab	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
NANOG	ChEA Transcription Factor Targets	1.0	null
ZNF512B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60523
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60225
BRD-K91084609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38275
Mad-Max complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.526
DMRT1	ChEA Transcription Factor Targets	1.0	null
due	GeneRIF Biological Term Annotations	1.0	null
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.306805
NANOG-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44085
CBX2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31171
somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.981084
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41743657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26591
CEBPB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7513
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF761	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22225
GSE188570,GSE188571_5_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.963
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12916
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-PRRX1-sequence_name_PRRX1	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960665
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.94955
H3C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50218
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.724723
HSP90AA1	Hub Proteins Protein-Protein Interactions	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX21_SOX21	Rummagene Transcription Factor Associations 2026	1.0	null
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82623
BRD-K01667746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04352
regions	GeneRIF Biological Term Annotations	1.0	null
MEL18_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
NCI-H1155	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE175787_13_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARNT	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57162
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45234
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
ACACB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2595
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.446935
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04834648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15744
Abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
GSE247764_1_v_2_nell2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
PMC12659123-12864_2025_12285_MOESM12_ESM.xlsx-Table_S12-Table_S12_Differentially_expressed_genes_after_SPI1_knockdown_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
PFKL_OE_GDS4410_202_human_biceps	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PTOV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82067
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3213
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05117
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.125609
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.04415
Nucleus preopticus medianus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.728
Familial hypophosphataemic rickets_Renal Tissue_GSE868	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.47333
Vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.993
Lymphosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10969
CHEK1_knockdown_136_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.12358
WASHC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60736
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01279
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27359
BRD-K28264750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09246
PGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64202
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.27132
mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
RNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81902
Glomerular Filtration Rate	DisGeNET Gene-Phenotype Associations	1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48558
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01118
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062159
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051679
ZFYVE19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86816
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46293
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60959
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15418
polygenic	GeneRIF Biological Term Annotations	1.0	null
BRD-K56131419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74166
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64663
Fascia dentata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
BRD-K45576113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18845
Myc-Max complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
EM2	CCLE Cell Line Gene CNV Profiles	1.0	2.3602
responsible	GeneRIF Biological Term Annotations	1.0	null
BRD-K84574164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12666
rd-es cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.951254
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Major depressive disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.722185
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.944
Rlc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.549
Skin disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
SYK_druginhibition_153_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.53624
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
GBGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12307
periventricular stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01836
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77454
P12-ICHIKAWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12209767-bcd-25-0099_supplementary_table_s2_suppst2.xlsx-C_DEGs_RNA-seq-Supplementary_table_S2C_List_of_differentially_expressed_genes_in_IGHUND_vs_IGH_GCB_MB2_DE_DLBCL_HGBCL-DH-BCL2_-BCL6_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.654
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.453621
hsa-miR-224	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4093
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941651
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
A_CA_04_2009_4dayMOI-10^4_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.35294
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00493
CREB3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32271
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20668
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065231
Round Face	DisGeNET Gene-Phenotype Associations	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38802
median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.63056
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19333
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0269
hsa-miR-4685-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78594
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
POFUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69647
AP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82695
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234302
Paraventricular hypothalamic nucleus, parvicellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88167
hsa-miR-549	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
RUNX3	ENCODE Transcription Factor Targets	1.0	null
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P6-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.965
pancreatic ductal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257572
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
BRD-K35472285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0639
TNKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50383
BRD-K74114857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00386
ZNF763	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91784
CRCGN015_MCF10A_48H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00495
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061104
Monogenic diabetes	ClinVar Gene-Phenotype Associations 2025	1.0	null
BRD-A14424697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03408
BRD-K08438266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11443
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
CDC14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63896
hsa-miR-1200	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
GSE153871_0_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12902236-mmc11.pdf-7-ENSG00000108924_HLF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46289
vagina	HPA Tissue Protein Expression Profiles	-1.0	-1.65498
CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Scapula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LIVF001-009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21808
Mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
increased susceptibility to weight gain	MPO Gene-Phenotype Associations	1.0	null
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_CT2_Splat 413	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01766
Bipolar Disorder_frontal cortex_GSE5389	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.69092
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7057
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.226
L428	CCLE Cell Line Gene CNV Profiles	1.0	1.50864
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86255
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.924986
indians	GeneRIF Biological Term Annotations	1.0	null
BRD-K41355409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75913
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19204
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18599462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81704
ChIP_STAT3_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06853
SW1990	DepMap CRISPR Gene Dependency	1.0	5.11512
PMC4340386__F1	PFOCR Pathway Figure Associations 2023	1.0	null
PMC1197416__F6	PFOCR Pathway Figure Associations 2023	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
attention deficit hyperactivity disorder	HPO Gene-Disease Associations	1.0	null
BRD-K91866516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17351
nucleus	GO Cellular Component Annotations 2015	1.0	null
Syndactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell differentiation	GO Biological Process Annotations 2015	1.0	null
SYTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16512
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_12136_KO_Dlx2_SRP339959	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.92362
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73361
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.783
SP2	ENCODE Transcription Factor Targets	1.0	null
Oromandibular-limb hypogenesis spectrum	ClinVar Gene-Phenotype Associations 2025	1.0	null
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
Medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE184087_0_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
set	GeneRIF Biological Term Annotations	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26963
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prader-Willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.671
obesity	HPO Gene-Disease Associations	1.0	null
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29498
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869097
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
FAM104A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47915
Seasonal affective disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91695
496100413_FWM_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.7758
NCCLMS1C1	DepMap CRISPR Gene Dependency	1.0	3.19399
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76188
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day14-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6032
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.61111
S117	CCLE Cell Line Gene Expression Profiles	1.0	1.62861
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055382
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06218527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02441
subcuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75532
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.464
ZDHHC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
BRD-K30910725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10399
BRD-K25905181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19504
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03113
micrognathia	HPO Gene-Disease Associations	1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95171
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.795191
Polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07312
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EW7	DepMap CRISPR Gene Dependency	1.0	2.68729
Obesity due to SIM1 deficiency	ClinVar Gene-Phenotype Associations 2025	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cancer	GAD High Level Gene-Disease Associations	1.0	0.293278
RNA polymerase II transcription regulatory region sequence-specific DNA binding	GO Molecular Function Annotations 2025	1.0	null
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55665
neonatal lethality	MGI Mouse Phenotype Associations 2023	1.0	null
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03806
abnormal facial shape	HPO Gene-Disease Associations	1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919949
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158266
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59336
hematopoietic system phenotype	MPO Gene-Phenotype Associations	1.0	null
somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.606916
Polymorphonuclear neutrophil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.183
Rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.509
Hepatic artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.501
ADPGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0636
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K94241935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1038
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18881
Basophilic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.72507
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.704
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13939
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35504
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.16245
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.955716
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51241
hsa-miR-767-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Shu complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.652
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122724
Neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
MDA-MB-157	GDSC Cell Line Gene Expression Profiles	1.0	1.44724
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21846
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
allele	GeneRIF Biological Term Annotations	1.0	null
tissue development	GO Biological Process Annotations 2015	1.0	null
Forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.591
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47563
Nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.702
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K96343889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0765
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921604
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79189
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
Hypopituitarism	DisGeNET Gene-Disease Associations	1.0	null
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.554791
abnormal white adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
Embryonic tracheal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
adipose tissue	GTEx Tissue Gene Expression Profiles	1.0	1.02267
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
HSPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3176
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37047
absent magnocellular neurosecretory cells	MGI Mouse Phenotype Associations 2023	1.0	null
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31026
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.8
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86294
HS852T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60476
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0952
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4296
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5948
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04104496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24083
Brain_CT2_Mmb 326	HuBMAP ASCT+B Annotations	1.0	null
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72497
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.51131
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.019
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31515
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71226
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12699
Macrolide transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.852
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dbf4-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77091
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40276277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58566
BRD-A55722685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12291
Sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46393
STAT3-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
biosynthetic process	GO Biological Process Annotations 2015	1.0	null
deficiency	GeneRIF Biological Term Annotations	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1992
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39832
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
abnormality of central nervous system electrophysiology	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21134
OVCAR-3	GDSC Cell Line Gene Expression Profiles	1.0	2.71086
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10127
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.64432
E2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71752
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ITPRIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8571
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58431
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A704	GDSC Cell Line Gene Expression Profiles	1.0	1.49384
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8444
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.42381
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
nt2d1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44159
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89262
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	0.863316
KYSE-450	GDSC Cell Line Gene Expression Profiles	-1.0	-1.87161
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20024676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07198
Autoimmune disease of musculoskeletal system	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MTF2	ChEA Transcription Factor Targets	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02337
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4761-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Rabies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.656
Sympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
pancreatic ductal carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23176
Brain_CT2_Mmb 332	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H3K27me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22585
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
hsa-miR-1207-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
holoprosencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.43941
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.19113
WAGR syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COL27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84243
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TBXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9205
RASAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4037
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A439-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11508
PMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47788
sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129744
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.185
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64970964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03331
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.64364
RING1B-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836847
RS4-11 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.527
BRD-K92910000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04402
TP53-20018659-R1E-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
blepharophimosis	HPO Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.20324
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Congenital leptin deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.1
ACBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00683
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47817
Autoimmune disease of skin and connective tissue	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
kidney	HPA Tissue Gene Expression Profiles	1.0	2.24597
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
Mdr2_KO_GDS1990_286_mouse_Livers of 12 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
periventricular stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24738
FSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89137
abnormality of movement	HPO Gene-Disease Associations	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2991
abnormal pituicyte morphology	MPO Gene-Phenotype Associations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.17027
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pituitary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175679
Thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.628
abnormal urine homeostasis	MPO Gene-Phenotype Associations	1.0	null
SPDEF_01_107	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.08946
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17395
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterus	GTEx Tissue Gene Expression Profiles 2023	1.0	0.536747
MAML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19806
abnormality of the cerebrum	HPO Gene-Disease Associations	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
[Ni-Fe] hydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.719
VPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54107
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.873
mantle zone of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32406
mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.807065
Parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.675
8505C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain_CT2_Mmb 332	HuBMAP ASCT+B Annotations	1.0	null
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.264
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36957
BRD-K76437403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18533
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044995
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
PMC12455829-11658_2025_792_MOESM8_ESM.xlsx-2_DDIT3_IP_vs_BRG1_IP-Unnamed_2_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26582498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39928
BRD-K67727634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08208
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414673
PEX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50668
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
PMC10828500-41467_2024_44701_MOESM4_ESM.xlsx-ST12-Unnamed_7_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
LGI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4731
PMC10185556-41467_2023_38439_MOESM3_ESM.xlsx-ST19_MR_results-associated_target_gene_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal eating behavior	HPO Gene-Disease Associations	1.0	null
HUT78	CCLE Cell Line Gene Expression Profiles	1.0	1.77383
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099962
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54115
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63797
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1442
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15987
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
aromatic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
growth abnormality	GWASdb SNP-Phenotype Associations	1.0	0.271584
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87177
embryonic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106194
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.22133
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.459203
should	GeneRIF Biological Term Annotations	1.0	null
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47208
layer 6 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14148
Hyperinsulinism	DisGeNET Gene-Disease Associations	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.442
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3127
Kleefstra syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.53564
detailed	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126345_11_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04868
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.952
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.745
Brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.511
HP1BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33954
GCNP_SHH_UP_EARLY.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27715
Necrosis	CTD Gene-Disease Associations	1.0	1.31297
abnormality of finger	HPO Gene-Disease Associations	1.0	null
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43481
pathogenic	GeneRIF Biological Term Annotations	1.0	null
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-01A-02R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obesity	GAD Gene-Disease Associations	1.0	null
BRD-K98934548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27114
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.44141
SCLY	ChEA Transcription Factor Targets	1.0	null
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69176
DAGLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70395
SARS-BatSRBD_Day1_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67679
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14424
r1 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0638
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
U138	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44421
alpha-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Medial habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35596
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86384
Narrow Nose	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-3692	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989428
Brain_CT2_Mmb 333	HuBMAP ASCT+B Annotations	1.0	null
Neuro-2a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
BRD-K94789179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76766
GSE175787_4_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEC63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94623
pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091991
abnormal blood cell morphology/development	MPO Gene-Phenotype Associations	1.0	null
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	1.81
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.312
Axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.514
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
ESRRA_01_280	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59797
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89607
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
ZBTB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07373
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC38A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37631
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the outer ear	HPO Gene-Disease Associations	1.0	null
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.582
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11298
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TDRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57512
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
AAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26333
performed	GeneRIF Biological Term Annotations	1.0	null
abnormal pituitary gland morphology	MPO Gene-Phenotype Associations	1.0	null
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Nucleus preopticus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
USP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51316
malformation of the heart and great vessels	HPO Gene-Disease Associations	1.0	null
Single-minded, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
abnormality of the face	HPO Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859093
short attention span	HPO Gene-Disease Associations	1.0	null
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05351
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08201
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.569
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59155687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18123
Mis6-Sim4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.481
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72975
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18477
NAA40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.71521
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23662
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.452427
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
IKBKG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70684
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841732
Puberty, Delayed	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.626
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	ChEA Transcription Factor Targets	1.0	null
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01441
BRD-K38381720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97474
independent	GeneRIF Biological Term Annotations	1.0	null
Diagonal band	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
D-392MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52378
PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_24_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.04051
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K85720719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01487
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
broxyquinoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25079
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066457
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16583
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.945
PLEKHF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.94414
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K25329768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39001
BRD-K09919985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03254
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45807
SEPTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51326
Intercostal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
Periplasmic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.404
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
Brachydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
ALKAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84992
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56337
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17086
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01709
abnormal hemoglobin content	MPO Gene-Phenotype Associations	1.0	null
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the orbital region	HPO Gene-Disease Associations	1.0	null
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
BT549	CCLE Cell Line Gene Expression Profiles	1.0	1.64322
EED-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K01991250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04497
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03709
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.44903
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37717
FOXP2	ENCODE Transcription Factor Targets	1.0	null
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42698
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.92733
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25084
UT7	CCLE Cell Line Gene CNV Profiles	1.0	1.84121
HCC2998	DepMap CRISPR Gene Dependency	1.0	2.33038
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053266
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02415
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060153
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47305
PMC11250262-41588_2024_1798_MOESM4_ESM.xlsx-ST18_665_top_menarche_genes-high_scorers_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
SP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carapace	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.851686
Brain_CT2_Mmb 333	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
localization	GeneRIF Biological Term Annotations	1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13204
Tongue muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K97949309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11265
BRD-K44341877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30539
Nuclear dicing body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30196
gamma-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
liminal alar domain of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20036
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86957
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Somite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.602
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46082
Pleural mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.664
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11042
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26831
BRD-K08190558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41109
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10416099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34507
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70511
Endodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
GSE184087_4_v_3_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11286
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.989609
Pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.297
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.824
BCL2L13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24923
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP281-27345836-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC3584306__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.35137
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lsd1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
ZNF343	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92054
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77738
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906
RING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61569
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
BRD-K21483524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68248
CACNA1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13457
OVCAR-8	GDSC Cell Line Gene Expression Profiles	1.0	1.66507
Estimated glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.373493
Epicotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.904
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
decreased cell death	MPO Gene-Phenotype Associations	1.0	null
C4orf46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47123
aplasia/hypoplasia affecting bones of the axial skeleton	HPO Gene-Disease Associations	1.0	null
TCOF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05393
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K45569026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17473
ONCODG1	CCLE Cell Line Gene Expression Profiles	1.0	2.2539
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09682
absent magnocellular neurosecretory cells	MPO Gene-Phenotype Associations	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1369
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2792
abnormal adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
Nucleus of the lateral lemniscus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15924
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06778
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11046
macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30996
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VPS26B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88578
Chromosome 1p36 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56861
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73859
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934746
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5694
BRD-K33505770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41309
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.55
FOXC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32989
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11898
HG3	DepMap CRISPR Gene Dependency	1.0	5.45744
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Integumentary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
clinodactyly of the 5th finger	HPO Gene-Disease Associations	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.040783
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.915712
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39839
link	GeneRIF Biological Term Annotations	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35428
arylhydrocarbon	GeneRIF Biological Term Annotations	1.0	null
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16247
polyphagia	MGI Mouse Phenotype Associations 2023	1.0	null
PMC8387919-mmc2.xlsx-ST9_NEUROG3_bound_TF_genes-Supplemental_Table_9_NEUROG3_bound_TFs_genes_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
f89	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14792
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13652
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.515317
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K07768565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07642
MDAMB468	CCLE Cell Line Gene Expression Profiles	1.0	1.56915
STK11IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82033
ewing's sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.717882
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
HYAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83573
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08861
deviation of finger	HPO Gene-Disease Associations	1.0	null
BRD-K60758969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0731
G6PC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33403
BRD-K05220907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0649
Syndromic X-linked intellectual disability Lubs type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19691
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subcutis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232599
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.96
SNUC2A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74558
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71906
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70695
sim1deficient	GeneRIF Biological Term Annotations	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.27551
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
similarities	GeneRIF Biological Term Annotations	1.0	null
BRD-K07740919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25042
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35431
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
agouti	GeneRIF Biological Term Annotations	1.0	null
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Imaginal disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.843
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
increased body length	MPO Gene-Phenotype Associations	1.0	null
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848159
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73359
floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01156
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00067
abnormal cns glial cell morphology	MPO Gene-Phenotype Associations	1.0	null
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
PRSS50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89655
peripheral primitive neuroectodermal tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17891
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
SUZ12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Memory Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91938
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02604
intracellular	GeneRIF Biological Term Annotations	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97466
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.524
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.945
SLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72397
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.12775
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52761
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesendoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11204
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.707
increased brown adipose tissue amount	MGI Mouse Phenotype Associations 2023	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.41858
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25102
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.97042
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51645
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
abnormality of the head	HPO Gene-Disease Associations	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	5.08071
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31158
TTC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50221
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35905
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.726
SUPT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32802
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.103
wc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27787
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48789
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39839
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49265
LAMA84	CCLE Cell Line Gene CNV Profiles	1.0	1.78794
SK-MEL-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
nucleobase-containing compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.539
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99716
rna biosynthetic process	GO Biological Process Annotations 2015	1.0	null
prominent nasal bridge	HPO Gene-Disease Associations	1.0	null
nucleus of the lateral olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80748
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07199
Superior mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.552
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10702
BRD-K93357133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42403
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
thiamphenicol-glycinate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03301
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
LARP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2902
Serum Albumin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
MS751	DepMap CRISPR Gene Dependency	1.0	2.60411
BRD-K17705111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29394
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.403
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.23616
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28143
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52877
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chromosome 2q37 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90099
MZ in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842736
SNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35454
CRCGN014_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2911
RGP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83904
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.435775
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106434
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.449194
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13964
increased circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PFKL_OE_GDS4410_75_human_Biceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K55505527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16929
abnormality of the mandible	HPO Gene-Disease Associations	1.0	null
Pituitary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.449
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.060628
M14	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58334
BRD-A06232236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11449
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.67151
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22346
HDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37139
ALL-PO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Condensed chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.378
periventricular stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80702
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.36307
Nuclear aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JARID2-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal food intake	MPO Gene-Phenotype Associations	1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.07356
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3968
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284607
Interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.157
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77317
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IRF3	ENCODE Transcription Factor Targets	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.075741
Retrosplenial area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44991
MANEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54713
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.871
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442962
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
abnormal energy homeostasis	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-3171	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
metabolic	GAD High Level Gene-Disease Associations	1.0	0.300704
hsa-miR-4728-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01203
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tetanus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
Anorexia nervosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
CRCGN008_HEPG2_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0903
abnormal hematopoietic system morphology/development	MPO Gene-Phenotype Associations	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
OPTN_KD_GDS2892_268_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
N4BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34813
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32975
Chromosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.626677
deviation of the 5th finger	HPO Gene-Disease Associations	1.0	null
BRD-K50330857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12738
ZNF354A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7459
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4287	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978958
hsa-miR-129-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POR_DELETION_GDS1093_240_mouse_Liver from male 3 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.903589
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08861
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63127
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890306
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.707
North Carolina macular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
abnormality of the 5th finger	HPO Gene-Disease Associations	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077025
Mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.279
TP63	ChEA Transcription Factor Targets	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital Separation Excessive	DisGeNET Gene-Phenotype Associations	1.0	null
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.8
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19953
TXNDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97352
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29139
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreatic Neoplasms	dbGAP Gene-Trait Associations	1.0	0.142669
POU5F1-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
MED16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78791
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33308
hsa-miR-4424	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.007
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	2.93234
impairment	GeneRIF Biological Term Annotations	1.0	null
BRD-K05789358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1771
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09309
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-103b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
abnormality of forebrain morphology	HPO Gene-Disease Associations	1.0	null
mice	GeneRIF Biological Term Annotations	1.0	null
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.643
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058242
Arnt-Sim1 complex	CORUM Protein Complexes	1.0	null
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15103
nxph1	GeneRIF Biological Term Annotations	1.0	null
sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.159997
GATA3	ENCODE Transcription Factor Targets	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24074
BRD-K18416855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28435
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
representing	GeneRIF Biological Term Annotations	1.0	null
Parametrial fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33469
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2132
SKOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.82426
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054242
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
Alstrom syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161716
biological regulation	GO Biological Process Annotations 2015	1.0	null
Avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.342
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Medial entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33439
PMC4521181-oncsis201520x8.pdf-16-ZNF292_ZNF292	Rummagene Transcription Factor Associations 2026	1.0	null
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75005
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.63206
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
Terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.373
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95875
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46804
PMC11735613-41467_2025_56054_MOESM6_ESM.pdf-13-SKI_SKI	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988453
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37281
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1305
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36262
preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.537416
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33678
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895825
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1_knockdown_135_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.87515
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54549
lateral parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32622
diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.58433
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077442
ASB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29705
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Arterial system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Feather calamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
index	GeneRIF Biological Term Annotations	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.550911
low	GeneRIF Biological Term Annotations	1.0	null
BRD-K14116382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10223
interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719934
abnormal pituitary gland size	MPO Gene-Phenotype Associations	1.0	null
BRD-K33748896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02505
Obesity	DisGeNET Gene-Disease Associations	1.0	null
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049142
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bulbous Nose	DisGeNET Gene-Phenotype Associations	1.0	null
Diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.766
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K03352392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55621
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2302
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22247
BRD-K96440230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75132
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
TAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08334
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3127
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12480102-41525_2025_515_MOESM2_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal neurohypophysis morphology	MPO Gene-Phenotype Associations	1.0	null
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53655
RI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98037
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.436778
MV411	DepMap CRISPR Gene Dependency	1.0	5.80305
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36883
cuneiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40367
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.624143
BRD-K45937240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04324
BRD-K08828851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.9234
Cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.52
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55536
SUPHD1	CCLE Cell Line Gene Expression Profiles	1.0	2.40672
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
HDLM-2	GDSC Cell Line Gene Expression Profiles	1.0	1.82818
DLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84113
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.224
G-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47072
nucleic acid-templated transcription	GO Biological Process Annotations 2015	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_2day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.4163
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.833642
enhancers	GeneRIF Biological Term Annotations	1.0	null
Nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.645
ETS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08153
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846474
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Pituicyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
isthmic part of the intermediate lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25102
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
BRD-K73442516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54237
BRD-K09117810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55746
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Menarche (age at onset)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.55229
metanephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.473869
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27802
lissencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382594
Paraflagellar rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
Cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.238
PMC7699880__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3781
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05115
Squamous Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1101
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.69046
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-507	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
melanocortin	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40142
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
CRCGN017_MCF10A.WT.HP_24H:N11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1207
BRD-K13542161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98869
RNF2	ChEA Transcription Factor Targets	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049496
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
CD164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9396
RBM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18577
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.83353
DU4475	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11317
hsa-miR-1233	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19355
aplasia/hypoplasia involving the skeleton	HPO Gene-Disease Associations	1.0	null
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82266
Condensed nuclear chromosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.132
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_1_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96627
PMC5644891__F1	PFOCR Pathway Figure Associations 2024	1.0	null
abnormality of limb bone morphology	HPO Gene-Disease Associations	1.0	null
PAS fold	InterPro Predicted Protein Domain Annotations	1.0	null
pancreatic cancer	GWASdb SNP-Disease Associations	1.0	0.778355
biomarkers	GeneRIF Biological Term Annotations	1.0	null
BRD-K47692589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06855
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.067607
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NRF2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.444085
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.26
TAF1	ENCODE Transcription Factor Targets	1.0	null
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24996
selected	GeneRIF Biological Term Annotations	1.0	null
PBX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53-20018659-R1E-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
protein heterodimerization activity	GO Molecular Function Annotations 2025	1.0	null
Crfk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08697
RMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
Tadpole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
Spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22661
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
ACVR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62299
radial deviation of the hand or of fingers of the hand	HPO Gene-Disease Associations	1.0	null
gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.293694
PMC9437808-mmc3.xlsx-IPA_Upstream_regulators-IPA_Upstream_regulator_analysis_Up_regulated_genes_following_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49528360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85632
child	GeneRIF Biological Term Annotations	1.0	null
BRD-K05799189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45211
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1338
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.10732
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.78184
CS-9665B (CASP3)	NURSA Protein Complexes	1.0	null
DLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73129
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
schizophrenia	GAD Gene-Disease Associations	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36884
Prominent Nasal Bridge	DisGeNET Gene-Phenotype Associations	1.0	null
Carpenter syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
pleural mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446038
Frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.828
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32788
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.997
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
CMPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17269
Retrosplenial area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3443
Forgetful	DisGeNET Gene-Phenotype Associations	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00121
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0824
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.305
Muscle Hypotonia	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-4649-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal energy expenditure	MPO Gene-Phenotype Associations	1.0	null
Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72007
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87428
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.36329
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41771
Sexual dysfunction	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.945
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6467-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7484
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
496100410_TCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.5538
abnormal protein level	MPO Gene-Phenotype Associations	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57207
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30122
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47212
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08091
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.860287
Lung squamous cell carcinoma_LUSC_TCGA-22-5480-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
paraventricular nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36013
strabismus	HPO Gene-Disease Associations	1.0	null
Arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87571
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.45055
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.65284
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926241
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aplasia/hypoplasia of the cerebrum	HPO Gene-Disease Associations	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
Hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.51
Type IV pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97427
MRPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86335
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54332
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
mc4r	GeneRIF Biological Term Annotations	1.0	null
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	1.62354
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
interstitial	GeneRIF Biological Term Annotations	1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10601
hsa-miR-4307	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
dna binding	GO Molecular Function Annotations 2015	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.554732
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.6608
AR	ChEA Transcription Factor Targets	1.0	null
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KU812	CCLE Cell Line Gene CNV Profiles	1.0	1.59832
abnormality of the calvaria	HPO Gene-Disease Associations	1.0	null
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0636
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Perturb_1214_KO_Zfp580/Zbtb7a/Klf16_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.86234
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.394508
Uniplex complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
exons	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53955
Monoclonal B-Cell Lymphocytosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K22797212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06759
MRPL20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8438
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Electroencephalogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1809
residues	GeneRIF Biological Term Annotations	1.0	null
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44391
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24738
PMC3470785-NIHMS377161-supplement-3.pdf-279-ZNF565_ZNF565	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
HDX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58127
JRKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3922
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GRHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2875
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.01174
abnormality of limbs	HPO Gene-Disease Associations	1.0	null
abnormality of the ocular region	HPO Gene-Disease Associations	1.0	null
Cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.23
PMC6556479__F1	PFOCR Pathway Figure Associations 2024	1.0	null
NR1H4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57946
VPREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39603
increased total body fat amount	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
language	GeneRIF Biological Term Annotations	1.0	null
BRD-K95735693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92491
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
VCB complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
tp63_16885358_squamous_epithelia_lof_human_gpl570_gds2088	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.947431
organic cyclic compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Prader-Willi Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Caudate putamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052385
Dravet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97729706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5954
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K18573205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60502
Stellate ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
obesity	GWASdb SNP-Phenotype Associations	1.0	0.689964
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.992
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77489
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24967
em3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34846
HOXC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43858
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
SUN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00193
sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.218715
susceptibility	GeneRIF Biological Term Annotations	1.0	null
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01597
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.542
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.624
NCIH1755	DepMap CRISPR Gene Dependency	1.0	3.35315
HINT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69234
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.176215
GSE134375_3_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
ELK1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K02881560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28492
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intercostal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.574816
GSE134375_6_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
PAS domain	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K19573822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17583
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
EED-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
phenotype	GeneRIF Biological Term Annotations	1.0	null
Nephroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
BRD-K18519876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66345
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.931662
OVCAR8	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
H4K20me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36783
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBL-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
predict	GeneRIF Biological Term Annotations	1.0	null
RNF2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormality of cerebral artery	GWASdb SNP-Phenotype Associations	1.0	0.276257
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DIFI	DepMap CRISPR Gene Dependency	1.0	2.54466
LHX1_NULL MUTATION - Ablation_GDS1748_748_mouse_Embryonic kidneys (from day E14.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83745
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25363217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34985
Neural lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
RT11284	CCLE Cell Line Gene Expression Profiles	-1.0	-2.06942
swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.578816
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6C_mageckTFkoscreen_wo_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49518
UBR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15938
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03646
statistically	GeneRIF Biological Term Annotations	1.0	null
observed	GeneRIF Biological Term Annotations	1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01996
hsa-miR-4663	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.86131
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.716651
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0676
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.15668
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67883
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.31841
DNA topoisomerase IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.627
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
significance	GeneRIF Biological Term Annotations	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9044
intermediate stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04173
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TYK2_KD_GDS4754_158_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24455
capan-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323874
CRCGN015_HEPG2_48H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44159
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862931
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13968
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64541
NIHOVCAR3	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CGGBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71848
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905709
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
singleminded	GeneRIF Biological Term Annotations	1.0	null
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90131
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.756604
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.10562
PKIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83658
BRD-K24557107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09057
PSMA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60098
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the periorbital region	HPO Gene-Disease Associations	1.0	null
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.127113
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.105
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Monogenic Obesity	DisGeNET Gene-Phenotype Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parabrachial nucleus, lateral division, external lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33262
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1397_KO_Psen1_SRP220423	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.24273
BRD-K75073699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12038
Abnormality Of Cardiovascular System Morphology	DisGeNET Gene-Disease Associations	1.0	null
FOXE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18518
protein binding	GO Molecular Function Annotations 2015	1.0	null
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
sexspecific	GeneRIF Biological Term Annotations	1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Thrombophilia	HuGE Navigator Gene-Phenotype Associations	1.0	null
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.064751
Prader-Willi-Like Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930159
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053364
nuclear	GeneRIF Biological Term Annotations	1.0	null
PMC7501145__F1	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09462
HCC202	DepMap CRISPR Gene Dependency	1.0	6.50976
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92081
Delayed Speech And Language Development	DisGeNET Gene-Phenotype Associations	1.0	null
sim1	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
metabolic process	GO Biological Process Annotations 2015	1.0	null
STAT3-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Amnioserosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.187646
B4GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1503
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
excludes	GeneRIF Biological Term Annotations	1.0	null
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
19286929-SuppTable2i	GeneSigDB Published Gene Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuroticism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
where	GeneRIF Biological Term Annotations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01506
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.49901
TRIM28	ChEA Transcription Factor Targets	1.0	null
POU2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03685
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24872
Rce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN014_HEPG2_3H:K04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02024
BRD-K28431799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59755
Brain_CT2_Mmb 329	HuBMAP ASCT+B Annotations	1.0	null
Hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
abnormality of the oral cavity	HPO Gene-Disease Associations	1.0	null
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93588
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.06097
MAPK1_knockdown_131_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.68813
Dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.529
abnormal size of the palpebral fissures	HPO Gene-Disease Associations	1.0	null
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08993
Cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.64329
HUT102	CCLE Cell Line Gene Expression Profiles	1.0	1.86187
increased susceptibility to diet-induced obesity	MPO Gene-Phenotype Associations	1.0	null
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09718
RNA polymerase II transcription regulatory region sequence-specific DNA binding	GO Molecular Function Annotations 2023	1.0	null
BRD-K27417269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93127
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54031
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.99918
abnormal erythrocyte morphology	MPO Gene-Phenotype Associations	1.0	null
increased susceptibility to diet-induced obesity	MGI Mouse Phenotype Associations 2023	1.0	null
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06853
C8166	CCLE Cell Line Gene CNV Profiles	1.0	1.34145
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04881
H3K9me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.865
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
PMC7781436-NIHMS1653552-supplement-Table_S2.xlsx-Variably_expressed_TFs-ZNF878_ZNF878	Rummagene Transcription Factor Associations 2026	1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
Posterior periventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22188
PHC1-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
EFO27	DepMap CRISPR Gene Dependency	1.0	3.04083
Mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.933
Basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091665
mesonephric epithelium development	GO Biological Process Annotations 2015	1.0	null
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17353
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
APOD_KO_GDS3913_487_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80167
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.9
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.48411
CSTF2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05404
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
SLITRK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9333
Short Foot	DisGeNET Gene-Phenotype Associations	1.0	null
poor	GeneRIF Biological Term Annotations	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
ZNF385C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67873
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75994
BRD-K19712167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38174
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15905
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875863
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844229
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32992
Diaphragm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45786
CTCF	ENCODE Transcription Factor Targets	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.919
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57668
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055175
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06014
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.521
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67492
SUDHL5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42934
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53795
evaluation	GeneRIF Biological Term Annotations	1.0	null
MIM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Inner mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.148
NANOG-16153702-HESC-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72453
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11012
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769027
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12387
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86758
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43158
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41514
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098033
BRD-K60454544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20399
Distal axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.658
manners	GeneRIF Biological Term Annotations	1.0	null
Catecholaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.43
rescued	GeneRIF Biological Term Annotations	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07287
KRAS.KIDNEY_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92393
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
POU5F1-16153702-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62852
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51012
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89321
UCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18533
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77336
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02165
ARAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14169
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.165
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hoxd1	GeneRIF Biological Term Annotations	1.0	null
Retrosplenial area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41646
TMED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34162
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
level	GeneRIF Biological Term Annotations	1.0	null
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Central amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
Midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.08
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-a-Classification_of_camel_SON_basal_genes_-_transcription_factors_SON	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neural tube defect	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056601
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65159
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hence	GeneRIF Biological Term Annotations	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57289
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31202
Obstructive sleep apnea_Hepatic Tissue_GSE1873	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.55018
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48732
Kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.378
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74509
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8258
attributable	GeneRIF Biological Term Annotations	1.0	null
Brain_CT2_Mmb 329	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U9-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69726
increased glycosylated hemoglobin level	MPO Gene-Phenotype Associations	1.0	null
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52295
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
body	GeneRIF Biological Term Annotations	1.0	null
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.081889
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	1.85817
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392309
Brachycephaly	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1255
Impotence	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.945
Lung adenocarcinoma_LUAD_TCGA-44-7667-01A-31R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0958
NEIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8532
TPGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10291
BRD-K50815029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2052
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927206
ZNF541	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39605
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2021
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34523
transcription cis-regulatory region binding	GO Molecular Function Annotations 2023	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
adipose tissue phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K41504921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38809
Polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
BRD-K19040732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01844
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04173
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.134398
MOLM16	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6757
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188570,GSE188571_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042269
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.1245
PMC10940914-mmc4.docx-0-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF782	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15299
abnormal body length	MPO Gene-Phenotype Associations	1.0	null
BRD-K69879051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2317
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41514
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5244
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88841
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16742
pancreatic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.144308
low-set, posteriorly rotated ears	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10703699-41588_2023_1554_MOESM3_ESM.xlsx-T6D_mageckTFkoscreen_with_BATF3-gene_BATF3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4756-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PML body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.512
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50092
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Axillary bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
ALDH1A2_KO_GDS4836_289_mouse_posterior embryonic brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NRF2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.923964
Extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184087_0_v_5_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14418
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
PMC12130184-12276_2025_1441_MOESM5_ESM.pdf-4-ZNF813_ZNF813	Rummagene Transcription Factor Associations 2026	1.0	null
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2030	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11376
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13757
Trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.744
HNT-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35066
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15628
TYKNU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14904
Cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.197
layer 2 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84128
PMC12480102-41525_2025_515_MOESM2_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62092
abnormal apoptosis	MPO Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9271
abnormality of calvarial morphology	HPO Gene-Disease Associations	1.0	null
Ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
regulation of gene expression	GO Biological Process Annotations 2015	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29305
B875 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
lateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71375
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pituitary gland hypoplasia	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36902
proximal	GeneRIF Biological Term Annotations	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
CYCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50858
Hoxc13_OE_GDS1890_174_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890891
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08262651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00104
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_10_v_3_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	177.113
GSE158834_7_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.67616
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59248
notochord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.465723
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of nervous system morphology	HPO Gene-Disease Associations	1.0	null
PTF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55654
G28T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.952351
GSE231799_3_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.16285
RPMI8402	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44921
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGDIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65534
BATF	ENCODE Transcription Factor Targets	1.0	null
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85465
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85933
FTC-133	GDSC Cell Line Gene Expression Profiles	-1.0	-1.94045
abnormal appendicular skeleton morphology	HPO Gene-Disease Associations	1.0	null
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00917
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
Anterior amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23467
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01811
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.957631
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
PTGER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70273
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
finger clinodactyly	HPO Gene-Disease Associations	1.0	null
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
STK36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96753
NAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19063
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55299
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE178532_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of facial skeleton	HPO Gene-Disease Associations	1.0	null
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
MEF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8383
RBBP5	ENCODE Transcription Factor Targets	1.0	null
HNT34	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46375
Disorder of sexual development	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Mushroom body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
PMC5352226-elife-20488-fig4-data5.xls-tfnames-ADNP_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of digit	HPO Gene-Disease Associations	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of brain morphology	HPO Gene-Disease Associations	1.0	null
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14642
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9286
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	0.874156
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54699
Macrocephaly	DisGeNET Gene-Disease Associations	1.0	null
involving	GeneRIF Biological Term Annotations	1.0	null
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98477
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-EN2-sequence_name_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
KDSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94234
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289939
POU2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88771
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_11_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BORCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49422
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66802
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
OCILY19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58518
scores	GeneRIF Biological Term Annotations	1.0	null
PAX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86071
Anus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
VPS52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0079
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
CNN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77791
Retrosplenial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25384
SAAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29836
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.26399
mesonephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.200092
embryonic neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33965
GSE158834_10_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4059
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49046
OAZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14731
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Salivary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75142
NCI-SNU-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.75052
PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.44477
Dominance, Cerebral	HuGE Navigator Gene-Phenotype Associations	1.0	null
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31915
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
Hyperphagia	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal forebrain morphology	MPO Gene-Phenotype Associations	1.0	null
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.04415
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
Occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59248
Erectile dysfunction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.6699
Myopia	DisGeNET Gene-Disease Associations	1.0	null
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.402
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.57042
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942596
CRCGN016_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08905
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97667
abnormal supraoptic nucleus morphology	MPO Gene-Phenotype Associations	1.0	null
GSE180951_6_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal neuronal migration	MPO Gene-Phenotype Associations	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
NFYB	ENCODE Transcription Factor Targets	1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983765
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25014
anomalous	GeneRIF Biological Term Annotations	1.0	null
Creatinine levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5901-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A78355490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34365
abnormality of body weight	GWASdb SNP-Phenotype Associations	1.0	0.341723
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61582
abnormal supraoptic nucleus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K27335290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05224
PMC7721881-41467_2020_20087_MOESM11_ESM.xlsx-Supplementary_Data_8B-MODY_genes_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14463
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
predispose	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31859
CAPAN1	DepMap CRISPR Gene Dependency	1.0	5.48789
PMC7699880__F2	PFOCR Pathway Figure Associations 2023	1.0	null
risk	GeneRIF Biological Term Annotations	1.0	null
Foregut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
klinefelter's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216332
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
Developmental Delay (Disorder)	DisGeNET Gene-Phenotype Associations	1.0	null
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72158
PMC12281655-CPB-26-6-935_SD1.pdf-18-ZNF200_ZNF200	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834641
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048824
WT-8 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.225
cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381755
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.965
Lung adenocarcinoma_LUAD_TCGA-55-8208-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MATCAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5208
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33615
PHC1	ChEA Transcription Factor Targets	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.075123
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
bardet-biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.512648
TNS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74201
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
abnormal hormone level	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
MOV10L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36432
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65239
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
Autism	DisGeNET Gene-Disease Associations	1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7825356-8844261.f3.docx-46-ZFHX2_ZFHX2	Rummagene Transcription Factor Associations 2026	1.0	null
MESSA	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46828
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72727
CRCGN015_MCF10A.WT.HP_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10807
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92523
Neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58894
PIK3R4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99065
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10695
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.309
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3529
Renal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
EGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86191
Irritable mood	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.830103
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
SLC9A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94512
MOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22298
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43428
EYA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79468
hsa-miR-3653	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
partially	GeneRIF Biological Term Annotations	1.0	null
mantle zone of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0362
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.14387
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70659
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989428
External ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
Kidney Chromophobe_KICH_TCGA-KL-8341-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.601
SLC2A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8857
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983093
BRD-K05802716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49021
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72365
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09412
CEBPD-23245923-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NFE2L2	ChEA Transcription Factor Targets	1.0	null
Dopaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.508
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
epithelium development	GO Biological Process Annotations 2015	1.0	null
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.860942
ARGLU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17048
BRD-K50689779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12279
SW1783	COSMIC Cell Line Gene Mutation Profiles	1.0	null
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.090446
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102870_11_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1679-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61725
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K13130949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07139
regulation of DNA-templated transcription	GO Biological Process Annotations 2023	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04143779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21246
abnormal brown adipose tissue amount	MPO Gene-Phenotype Associations	1.0	null
19168792-TableS2	GeneSigDB Published Gene Signatures	1.0	null
abnormal gland morphology	MPO Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EB-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal hematopoiesis	MPO Gene-Phenotype Associations	1.0	null
GOLGA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27963
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4774-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CRCGN011_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3523
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103596
JARID2-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RhoGDIbeta_KD_GDS2864_634_human_MDA-MB-231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
transcription cis-regulatory region binding	GO Molecular Function Annotations 2025	1.0	null
SARS-CoV_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60415
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20928
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33349
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.32259
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.073843
BRD-K42582718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08369
tagsnp	GeneRIF Biological Term Annotations	1.0	null
insulin resistance	MGI Mouse Phenotype Associations 2023	1.0	null
TRAPPC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04592
NUDT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67009
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	4.01539
Protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
BRD-K64215435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50537
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
BRD-K56915252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24052
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84863
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
aplasia/hypoplasia involving bones of the skull	HPO Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5470-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.925789
Mammary Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Wing bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.921
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
Cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5857
GRHL2-25758223-PLACENTA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
not applicable_cell type comparison_GSE49439_365_human_podocytes and progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-3130-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60291
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Anterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
Body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.439
RAD21	ENCODE Transcription Factor Targets	1.0	null
Entorhinal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56453
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24116
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89651
loss	GeneRIF Biological Term Annotations	1.0	null
C bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.946825
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13549
BRD-K08142337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23829
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07642
Optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.686
BRD-K60131990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90941
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7509
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.04415
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8512
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6057
orbit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217139
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19A-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal cell migration	MPO Gene-Phenotype Associations	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.019
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Stomodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
developmental process	GO Biological Process Annotations 2015	1.0	null
Obstructive sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
mouth neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.52536
BRD-K99127896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1188
Rto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
BRD-K06743908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41283
Infundibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.419
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77897
BRD-K60161601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02529
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF593	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84645
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48785
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
completely	GeneRIF Biological Term Annotations	1.0	null
Hypertropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
TPRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81793
COX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36625
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RTL8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40874
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.987662
GSE121198,GSE129779_0_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral part of alar m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20036
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67047
significant	GeneRIF Biological Term Annotations	1.0	null
OCILY3	CCLE Cell Line Gene Expression Profiles	1.0	1.52616
cancer	GWASdb SNP-Disease Associations	1.0	0.062051
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844229
Body size at age 10	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.55229
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01081
SORL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5072
GSE100102_4_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28535931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99448
Occipital pole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.513
BRD-K16604405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32711
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80102
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.989428
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.322
BRD-K84386253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09052
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A77907596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08605
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60827
Smooth septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
PMC6556479__F1	PFOCR Pathway Figure Associations 2023	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8612
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1809
ZNF281	ChEA Transcription Factor Targets	1.0	null
SYM-2206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35613
SLIK (SAGA-like) complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
19074870-SuppTable4a	GeneSigDB Published Gene Signatures	1.0	null
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
SEC24B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76127
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54702
PancreaticIslet	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1832
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
short digit	HPO Gene-Disease Associations	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31332
RAB5IF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09202
Narcolepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
Embryonic brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66574
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
intron	GeneRIF Biological Term Annotations	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
isthmic liminal reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.79623
PMC12464728-HSR2-8-e71283-s008.pdf-373-ZNF148_ZNF148	Rummagene Transcription Factor Associations 2026	1.0	null
Periventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02833
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35504
complete neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41561756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14143
SNU-423	GDSC Cell Line Gene Expression Profiles	1.0	1.86817
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-557	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.525
abnormal hypothalamus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
SLC27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91478
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04911
BATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63203
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.031984
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8635
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56195
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72965
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KURAMOCHI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98086
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74304
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33924
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054121
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.762
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32721
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
protein heterodimerization activity	GO Molecular Function Annotations 2023	1.0	null
PMC5735185-41467_2017_1200_MOESM4_ESM.xlsx-Table_S1-Choi_et_al_2016_DUX4_up-regulated_targets_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9073
LDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
vitro	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHMAC5	DepMap CRISPR Gene Dependency	1.0	5.17776
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11243
increased body weight	GWASdb SNP-Phenotype Associations	1.0	0.689964
Tapering Fingers (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29987
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
autistic behavior	HPO Gene-Disease Associations	1.0	null
BRD-A38066207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35579
GOT1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77042
MIST1_KO_GDS1731_758_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DMTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97516
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K77797840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28323
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
UPCISCC026	DepMap CRISPR Gene Dependency	1.0	2.83773
ERCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60649
aplasia/hypoplasia of the mandible	HPO Gene-Disease Associations	1.0	null
BRD-K36468214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83674
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76027
ZNF425	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1938
PAC motif	InterPro Predicted Protein Domain Annotations	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975243
increased food intake	MPO Gene-Phenotype Associations	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934746
HEATR5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19151
kidney epithelium development	GO Biological Process Annotations 2015	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40953
JUND	ENCODE Transcription Factor Targets	1.0	null
abnormal glial cell morphology	MPO Gene-Phenotype Associations	1.0	null
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00343
BPH1	DepMap CRISPR Gene Dependency	1.0	5.08702
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72352
envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.484079
abnormal neuronal migration	MGI Mouse Phenotype Associations 2023	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
PCYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41208
aplasia/hypoplasia involving the central nervous system	HPO Gene-Disease Associations	1.0	null
increased circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
COX6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88933
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15318
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02435
BRD-K08241590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79707
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41647
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78819
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17222
BRD-K53752646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11244
Syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40773
EIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62808
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.08309
PMC6788756__F2	PFOCR Pathway Figure Associations 2024	1.0	null
obese	MPO Gene-Phenotype Associations	1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11657
HUH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.09578
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.435775
abnormality of the upper limb	HPO Gene-Disease Associations	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
Ventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.63
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
power	GeneRIF Biological Term Annotations	1.0	null
abnormal pituicyte morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE128730_0_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKMEL31	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51596
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ethnicity	GeneRIF Biological Term Annotations	1.0	null
PMC1197416__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.61101
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.034
BRD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59535
gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.569622
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18646
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35334
HDAC_INHIBITION - trichostatin A_GDS2452_709_human_Endothelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20666
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35177
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33888
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.890074
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
common	GeneRIF Biological Term Annotations	1.0	null
Globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.556
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	0.259986
PBX1-22567123-OVCAR3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.044176
Metanephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
Periventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
SLC35B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02703
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.575
BRD-K61555339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30315
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-8_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-564	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045326
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.312597
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.206
hsa-miR-3177-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Borderline personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08091
BRD-K04518829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11989
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043565
Formate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01118
GSE103068_5_v_8_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
SH4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88554
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PECAPJ15	CCLE Cell Line Gene Expression Profiles	-1.0	-1.70271
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70242
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16914
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406694
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.431
contribute	GeneRIF Biological Term Annotations	1.0	null
Glutamatergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
Perturb_1209_KO_Zbtb7a/Klf16_SRP302435	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.23473
abnormal circulating protein level	MPO Gene-Phenotype Associations	1.0	null
cerebral arterial disease	GWASdb SNP-Disease Associations	1.0	0.353691
exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175772
GSE158834_11_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116829
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pleural cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325335
ALKBH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60795
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMYD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93269
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.92684
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.502693
BRD-K15378071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18713
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.37188
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64485
Inner kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.971
KDM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8164
morbid obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.601
Hypopituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Strabismus	DisGeNET Gene-Disease Associations	1.0	null
H3-3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36771
SAMD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59913
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043741
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27728416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01804
olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341863
lateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60481
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
posteroventral (inferior) parietal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14384
tapered finger	HPO Gene-Disease Associations	1.0	null
BRD-K86237035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98792
PMC10185556-41467_2023_38439_MOESM3_ESM.xlsx-ST19_MR_results-nearest_gene_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE254155_5_v_0_per2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6451
SMAD4	ChEA Transcription Factor Targets	1.0	null
deviation of the hand or of fingers of the hand	HPO Gene-Disease Associations	1.0	null
PMC6788756__F2	PFOCR Pathway Figure Associations 2023	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
bl20	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
Iris color (L* coordinate)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.37631
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69778
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.20811
20436685-ST6-1	GeneSigDB Published Gene Signatures	1.0	null
neurological speech impairment	HPO Gene-Disease Associations	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05921
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.195
CHD2	ENCODE Transcription Factor Targets	1.0	null
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
snp	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-938	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	9.33332
BCPAP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61971
hsa-miR-544b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
abnormal nervous system tract morphology	MGI Mouse Phenotype Associations 2023	1.0	null
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865111
BRD-K76677554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00131
Cyclotropia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.61811
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13508
Brain_CT2_Mmb 326	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
Posterior paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
BRD-K36278687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49889
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66235
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.457214
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX2-sequence_name_MSX2	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936895
6q16 copy number variation	WikiPathways Pathways 2024	1.0	null
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6095_KD_ZNF207_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Insect tracheal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
GPR50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73701
SNU1077	CCLE Cell Line Gene CNV Profiles	1.0	1.64051
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0377
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05518
system development	GO Biological Process Annotations 2015	1.0	null
Dura mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04173
all	GWASdb SNP-Phenotype Associations	1.0	0.0417
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09692
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11881
Parabrachial nucleus, lateral division, superior lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53378
GSE134375_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
DMRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79667
PMC11282827-40659_2024_524_MOESM5_ESM.xlsx-MSX1-sequence_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047734
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
P2URK562	DepMap CRISPR Gene Dependency	1.0	4.13832
yellow	GeneRIF Biological Term Annotations	1.0	null
learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.457487
Low Set Ears	DisGeNET Gene-Disease Associations	1.0	null
median	GeneRIF Biological Term Annotations	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.945
BRD-K14193598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30085
9+2 motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
abnormality of limb bone	HPO Gene-Disease Associations	1.0	null
RAB39A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91678
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.191
Hyperglycemia	CTD Gene-Disease Associations	1.0	2.88009
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.118645
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
Clonei	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02304
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.30604
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sexual dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.618
abnormality of body height	HPO Gene-Disease Associations	1.0	null
endocrine pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.112743
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88087
hsa-miR-3140-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
BRD-K45237033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5893
Language Development Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_3_v_1_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.642615
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
increased circulating insulin level	MGI Mouse Phenotype Associations 2023	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73376
FIZZ2_KO_GDS4902_409_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.947
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.747
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S4-Table_S4_Top_500_differentially_modified_gene_bodies_between_AA_and_EA_patients_with_MM_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874138
BRD-K60166659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23258
Histaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.225
gentamycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.25937
JARID2	ChEA Transcription Factor Targets	1.0	null
SKRC31	DepMap CRISPR Gene Dependency	1.0	3.09859
Intrinsic component of periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00974016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50183
cerebral aneurysm	GWASdb SNP-Phenotype Associations	1.0	0.512499
Metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.1
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
help	GeneRIF Biological Term Annotations	1.0	null
Nephrolithiasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sensorimotor area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10311_KO_Dkk3_SRP067265	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.33945
HCC70	GDSC Cell Line Gene Expression Profiles	1.0	1.70709
abnormal magnocellular neurosecretory cell morphology	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-520a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organelle inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.790564
BCAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16641
Sima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.323
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.76205
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.967147
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48234
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45081
BRD-K38858314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04497
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.725
CAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE184087_2_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97388
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58258
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormal limbic system morphology	MPO Gene-Phenotype Associations	1.0	null
l2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11958
regulation of transcription by RNA polymerase II	GO Biological Process Annotations 2023	1.0	null
DNM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81683
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55422
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58584
hsa-miR-3922-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
abnormal astrocyte morphology	MPO Gene-Phenotype Associations	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074311
CRCGN011_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6598
ewing's family tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.380251
Holoprosencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
PMC8948606-7488708.f2.docx-6-ZBTB8B_ZBTB8B	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.497
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32992
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
muscular hypotonia	HPO Gene-Disease Associations	1.0	null
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52235
UBE2Q1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49891
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048484
OMC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
increased body size	MPO Gene-Phenotype Associations	1.0	null
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38109
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62872
skeletal muscle cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126112
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
TGFBR3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78021
BRD-K55147629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02014
BRD-K93101873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17486
Dorsal hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
PMC9050671-41598_2022_10725_MOESM1_ESM.docx-4-NFE2L1_NFE2L1	Rummagene Transcription Factor Associations 2026	1.0	null
region	GeneRIF Biological Term Annotations	1.0	null
Iliac artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.37
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4921
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4864
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78782
BRD-K74512976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45096
Global Developmental Delay	DisGeNET Gene-Disease Associations	1.0	null
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66579
increased urine glucose level	MPO Gene-Phenotype Associations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.281453
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32862
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
JHH1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90423
AGXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49361
hsa-miR-3926	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08863
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
Breast Neoplasms	CTD Gene-Disease Associations	1.0	2.88009
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16484
icSARS-Cov_Day2_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.76205
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
them	GeneRIF Biological Term Annotations	1.0	null
TRAPPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17918
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
microcephaly	HPO Gene-Disease Associations	1.0	null
BRD-K08110534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24142
Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.118
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.31943
PAS fold-3	InterPro Predicted Protein Domain Annotations	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4884
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25153
europeans	GeneRIF Biological Term Annotations	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
MCAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405176
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211474,GSE212779_8_v_5_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231799_2_v_5_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16852
HK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26619
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.15669
Cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.248
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
as91	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
VPS4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52147
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.773589
Secondary motor area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08113
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-indep_3dpt-SYMBOL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.81
intracranial arterial disease	GWASdb SNP-Disease Associations	1.0	0.353691
Feather bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.216
21152935-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Brain_CT2_Splat 414	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34127
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38022
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
LOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08381
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39904
lateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55196
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4633-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.704
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051421
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal hemoglobin	MPO Gene-Phenotype Associations	1.0	null
SNU423	CCLE Cell Line Gene Expression Profiles	1.0	1.47095
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03417
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.09038
TE9	CCLE Cell Line Gene Expression Profiles	-1.0	-2.20951
Cervix Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3858
Fourth ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.848
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
isthmus proper	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62405
increased susceptibility to weight gain	MGI Mouse Phenotype Associations 2023	1.0	null
Organum vasculosum laminae terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25722
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38376
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.652
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
one	GeneRIF Biological Term Annotations	1.0	null
NCI-H1436	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059565
NS-0 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.603
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.704
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9522
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
TUBA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40287
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07339
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.948132
COLO-824	GDSC Cell Line Gene Expression Profiles	1.0	2.22709
BRD-K02053819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12081
hsa-miR-4720-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04808
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33878
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97599
BRD-K18368161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39362
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.624
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal nervous system electrophysiology	HPO Gene-Disease Associations	1.0	null
mitochondrial membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.838269
GSE246053_4_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.453
m2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23992
BRD-K04706894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01258
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37285
BRD-K57271749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54317
mass	GeneRIF Biological Term Annotations	1.0	null
deletion	GeneRIF Biological Term Annotations	1.0	null
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78691
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52997
Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FBXO27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92925
BRD-K33943748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75558
Neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.0
diagnosis	GeneRIF Biological Term Annotations	1.0	null
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.996
obsessive-compulsive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
abnormality of skull size	HPO Gene-Disease Associations	1.0	null
Nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.575
hyperphagia	GeneRIF Biological Term Annotations	1.0	null
B3GNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7156
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.704
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15024
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046494
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26646
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
MRPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77974
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59248
Endopeduncular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21046
BRD-K15373812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4294
TT	GDSC Cell Line Gene Expression Profiles	1.0	1.87882
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.972537
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10768
Peripheral Nervous System Diseases	CTD Gene-Disease Associations	1.0	2.88009
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49002
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.854
EMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87629
NETO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65427
Set3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.9
ZNF658	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5791
subcutaneous adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255234
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.335814
CRX-20693478-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
m1Lim (VL) part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25102
abnormal cell physiology	MPO Gene-Phenotype Associations	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32056
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12783
exhibit	GeneRIF Biological Term Annotations	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC5417597-pone.0176679.s006.xlsx-Tumor_MLL_vs_AT1-Unnamed_1_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
GSE174735_2_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Parametrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.96966
TSEN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32855
hyperglycemia	MGI Mouse Phenotype Associations 2023	1.0	null
GSE158834_1_v_8_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
cephalothin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01266
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86082
Myc-type, basic helix-loop-helix (bHLH) domain	InterPro Predicted Protein Domain Annotations	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.704
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6342
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64201
cell type cancer	GWASdb SNP-Disease Associations	1.0	0.264826
Diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0557
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.90832
Waist-to-hip ratio adjusted for BMI x sex interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.522185
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
Kidney Chromophobe_KICH_TCGA-KN-8435-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16157
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91273
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1003
increased urine glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K04195898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22998
NCC010	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.854
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99162
Pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
BRD-K53146097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2022
Clinodactyly	DisGeNET Gene-Disease Associations	1.0	null
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88152
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.41426
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
paraventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7335
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04033
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.287
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65947
Glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.869897
Posterior amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
NRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11476
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
spleen	HPA Tissue Protein Expression Profiles	1.0	1.04415
hsa-miR-4487	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
WM793	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48455
EZH2	ChEA Transcription Factor Targets	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.266408
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892823
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.120242
HADHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67398
BJAB cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
BRD-K38854468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03276
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18771
ChIP_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69645
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9921
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01301
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.635
BRD-K30055322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00686
SIM1-associated metabolic syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
mantle zone of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62405
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perirhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
Multicellular trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
protein heterodimerization activity	GO Molecular Function Annotations 2015	1.0	null
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6479
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
LDL cholesterol levels in current drinkers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.21131
Olfactory placode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
CLOCK-BMAL transcription complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.293
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.65498
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
HUS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90663
Edema	CTD Gene-Disease Associations	1.0	1.14954
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00615
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040468
HMGN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08615
abnormality of the hand	HPO Gene-Disease Associations	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844229
abnormal white adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
ewing's sarcoma family tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.593247
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3012-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypogonadotropic hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.751
KE97	CCLE Cell Line Gene Expression Profiles	1.0	1.47645
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.1411
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hypoplasia	DisGeNET Gene-Phenotype Associations	1.0	null
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.496
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-43-KLF4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930159
BRD-K03383196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60715
BRD-K00976973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07397
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
BRD-K51490423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02841
EFO-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
lateral SC part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3564
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
low-set ears	HPO Gene-Disease Associations	1.0	null
long fingers	HPO Gene-Disease Associations	1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4911
neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.915215
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
spot	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of globe location	HPO Gene-Disease Associations	1.0	null
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.847
DNAJB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99789
16489042-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF467	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65467
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34813
BRD-K44797874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15695
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08121
PMC7371429-elife-53600-supp2.xlsx-annotated_MEIS1_in_B13ko-M1-Gene_Name_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5527282-ncomms16041-s4.xlsx-sheet1-Supplementary_Data_3_Predicted_upstream_transcription_factors_of_M_LPS_-_signatures_using_Ingenuity_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal muscle tone	HPO Gene-Disease Associations	1.0	null
BRD-K08043579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56679
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SRF_SRF	Rummagene Transcription Factor Associations 2026	1.0	null
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35334
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.914697
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11682006-13105_2024_1045_MOESM1_ESM.pdf-25-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01441
vascular disease	GWASdb SNP-Disease Associations	1.0	0.072197
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
macrocephaly	HPO Gene-Disease Associations	1.0	null
Puberty, Precocious	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3285
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.04859
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal paraventricular hypothalamic nucleus morphology	MPO Gene-Phenotype Associations	1.0	null
Primary hyperaldosteronism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
SP1	ENCODE Transcription Factor Targets	1.0	null
Hypomyelinating leukodystrophy 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.59557
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.738
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.26514
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51014
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CELSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76814
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43888
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26462
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.08039
Nape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
PMC7793767-fendo-11-609271.nxml--GWAS_genes_changed_in_AA_vs_controls_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
measures	GeneRIF Biological Term Annotations	1.0	null
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3227
BRD-K53387776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01158
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pedunculopontine nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65842
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055716
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95526
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal brain morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K32856496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33176
BRD-K30750630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6774
Intrinsic component of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35504
Low Grade Cervical Squamous Intraepithelial Neoplasia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K24205443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12229
SW954	DepMap CRISPR Gene Dependency	1.0	3.53949
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75553
BCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47916
BRD-K04785821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69479
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320956
BRD-K14987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30758
dorsolateral (non-cerebellar) part of isA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37658
abnormal conjugate eye movement	HPO Gene-Disease Associations	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
TC-YIK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MEK_OE_GDS1925_165_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-A96537953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8342
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.832
Down Syndrome	DisGeNET Gene-Disease Associations	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57351233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25876
cellular nitrogen compound biosynthetic process	GO Biological Process Annotations 2015	1.0	null
obese	MGI Mouse Phenotype Associations 2023	1.0	null
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.971
BRD-K17852428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0761
BST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82319
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65375
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64716
PMC11333005-ppat.1012426.s020.xlsx-ISGs_IFNb_up_IRF9-indep_3dpt-ENSEMBL_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91180296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71071
abnormality of the mouth	HPO Gene-Disease Associations	1.0	null
Lantern muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.697
mantle zone of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20036
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05411
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0018
FOXM1-26100407-CHIP-SEQ-HEK293-FLP-IN-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
higher	GeneRIF Biological Term Annotations	1.0	null
Polycystic Ovary Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72729
UACC893	CCLE Cell Line Gene CNV Profiles	1.0	1.49409
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
severe acute respiratory syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.394863
GSE164874_5_v_2_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85572169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08544
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.984
abnormal neuron physiology	MPO Gene-Phenotype Associations	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.937637
Anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.512
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.58388
BMI1_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.438542
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.5886
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11030494-media-2.xlsx-ST12-Supplementary_Table_12_Genes_identified_by_MAGMA_as_being_significantly_associated_with_the_internalizing_spectrum_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69921
Rhabdomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
ZNF496	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77624
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
WM3772F	DepMap CRISPR Gene Dependency	1.0	4.27894
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98808
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
regulation of cellular macromolecule biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
NCI-H520	GDSC Cell Line Gene Expression Profiles	-1.0	-2.11179
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00793
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25804113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49344
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4161
dorsolateral IC periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11805
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11204
15489324-TableS2	GeneSigDB Published Gene Signatures	1.0	null
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12507
longitudinal	GeneRIF Biological Term Annotations	1.0	null
APOBEC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2701
Mammary Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195786_3_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28691
interpreted	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53497
neuroepithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.650966
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9933
Neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.256
MED19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16875
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104999
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.09
PMC11030494-media-2.xlsx-ST12-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21365
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69597
skin	GTEx Tissue Gene Expression Profiles	1.0	0.962822
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
DICER1_KO_GDS4504_585_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-3146	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.027
GSE96544_1_v_0_mebendazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88926
Motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.85
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
Brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.998
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cognitive impairment	HPO Gene-Disease Associations	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44733
SUZ12_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RALDH2_KO_GSE43578_6_mouse_head (rostral or posterior)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79749
BRD-K25081034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03522
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03288
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.327
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7943
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40559
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
revealed	GeneRIF Biological Term Annotations	1.0	null
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41514
CEBPD	ChEA Transcription Factor Targets	1.0	null
CEP164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.93729
OTUD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3895
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.709
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00871
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65159
bone cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215653
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03548
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18272
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.880944
SP4	ENCODE Transcription Factor Targets	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02751
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06772
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Psychosexual disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2375
RO82-W-1	GDSC Cell Line Gene Expression Profiles	1.0	1.45586
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14785
BRD-K59744424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21595
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.74
Prechordal mesendoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.046
BRD-A51381734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02787
ZNF232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31258
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.04352
gramine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86785
MERO82	DepMap CRISPR Gene Dependency	1.0	2.1237
abnormal nasal morphology	HPO Gene-Disease Associations	1.0	null
LU65	DepMap CRISPR Gene Dependency	1.0	3.16059
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74579
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.715
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.65498
Postural Hypotension With Compensatory Tachycardia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.862931
Periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.807
t59-kidney_female_1w	MoTrPAC Rat Endurance Exercise Training	-1.0	-1.89232
ChIP_EED_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K98496939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15557
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
insulin resistance	MPO Gene-Phenotype Associations	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.371107
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
benign	GeneRIF Biological Term Annotations	1.0	null
abnormal body fat mass	MPO Gene-Phenotype Associations	1.0	null
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19453
increased body weight	HPO Gene-Disease Associations	1.0	null
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2862
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24388
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950162
H2BC11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17102
STAT1	ChEA Transcription Factor Targets	1.0	null
ChIP_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46458
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54361
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
BRD-K17609687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75453
Posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
cellular process	GO Biological Process Annotations 2015	1.0	null
MPPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59246
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.122
GSE190534,GSE190536_0_v_2_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89731
Subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25831
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46026
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.080308
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91125
Outer membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.007
BRD-K11504463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2738
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74264
carboplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92408
light-harvesting complex, core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70519
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
PYCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01503
abnormal circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
BRD-K29130550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28718
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6787
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.943182
mitochondrial envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.545648
Neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.206
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4356
Depression	DisGeNET Gene-Disease Associations	1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9843
PMC8140076-41467_2021_23294_MOESM3_ESM.xlsx-Spinal_Interneuron_Domains-LHX2_LHX2	Rummagene Transcription Factor Associations 2026	1.0	null
Microretrognathia	DisGeNET Gene-Phenotype Associations	1.0	null
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.9839
samples	GeneRIF Biological Term Annotations	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.794375
PMC11258892-NIHMS2003533-supplement-MMC6.pdf-35-ZNF587_ZNF587	Rummagene Transcription Factor Associations 2026	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48461
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12880737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27672
tcf7l1	GeneRIF Biological Term Annotations	1.0	null
Impotence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
Autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.718
BRD-K96713984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28545
Hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Psoriasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48921
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
CHGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14866
ZMIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86025
a15	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.965981
SEMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07546
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.043434
neuroectodermal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.284728
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRO-AP2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
CCDC136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53744
RUNX2	ChEA Transcription Factor Targets	1.0	null
SEC61A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63642
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
population	GeneRIF Biological Term Annotations	1.0	null
BRD-K24929039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21779
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.06616
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049651
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13874
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64871
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832883
XKR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99473
MGH-U3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Capitate projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.517
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.097
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11369
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.38547
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218060_1_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73702
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15578
ahr_19454665_epidermal_langerhans_cell_lof_mouse_gpl339_gds3575	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.494692
BRD-K01030150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74234
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
Sociability score	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88401
another	GeneRIF Biological Term Annotations	1.0	null
increased total body fat amount	MGI Mouse Phenotype Associations 2023	1.0	null
ChIP_PHC1_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
growth delay	HPO Gene-Disease Associations	1.0	null
decreased energy expenditure	MPO Gene-Phenotype Associations	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC4196905-pone.0109569.s008.xlsx-Intersection-AHR_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
CENPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05935
abnormality of the nasal bridge	HPO Gene-Disease Associations	1.0	null
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29524
Developmental and epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.137
HPRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07963
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76214
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95262
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16441
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.387795
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.189
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.17959
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87197
PMC4467679-12967_2015_546_MOESM3_ESM.csv--TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	-1.0	-1.65498
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
KDM4C_natural variation_GSE41040_589_human_fibroblasts fron neonatal foreskin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K86711517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26239
BRD-K56893290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16853
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.4674
major	GeneRIF Biological Term Annotations	1.0	null
CABIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01379
SNU423	CCLE Cell Line Gene CNV Profiles	1.0	1.62552
hsa-miR-3188	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94134
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07087
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48252
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.869482
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-2.06924
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.432023
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0094
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36841620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01657
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-468	GDSC Cell Line Gene Expression Profiles	1.0	1.58385
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39891
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the palpebral fissures	HPO Gene-Disease Associations	1.0	null
leptinmelanocortinoxytocin	GeneRIF Biological Term Annotations	1.0	null
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22966
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25016
aneurysm	GWASdb SNP-Phenotype Associations	1.0	0.318934
pancreatic duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187558
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
abnormal white adipose tissue morphology	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9557
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF473	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64148
effects	GeneRIF Biological Term Annotations	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.088787
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05791
hypertelorism	HPO Gene-Disease Associations	1.0	null
Cotyledonary node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22497
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SOX6-21985497-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K19575490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64658
DNA replication factor C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.263
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68186
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
PRMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12756
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.580828
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.46978
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35954
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
Kidney Chromophobe_KICH_TCGA-KN-8431-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ADNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04737
critical	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19097
Dendritic branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GRHL2_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.260202
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the eyelid	HPO Gene-Disease Associations	1.0	null
FES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86586
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
molecular_function	GO Molecular Function Annotations 2015	1.0	null
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22986
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1398
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80219
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.20042
BRD-K02691653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53513
BRD-K05734090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35678
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36176
snps	GeneRIF Biological Term Annotations	1.0	null
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28891
isotretinoin_homo sapiens_gpl8300_gds3215	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.40661
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9582
KCTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02287
BRD-K20737562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35935
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07232
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
preisthmic midbrain tectum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24174
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.845
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87709
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormal hypothalamus morphology	MPO Gene-Phenotype Associations	1.0	null
Brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.329
GSE221539_1_v_3_lrrc10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular phenotype	MPO Gene-Phenotype Associations	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	1.0	1.04415
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1296	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	5.06975
PMC7794364-41540_2020_161_MOESM3_ESM.xlsx-NSP_Unique_-_PPH2_predictions-Gene_Sym_SMAD9	Rummagene Transcription Factor Associations 2026	1.0	null
RAP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96638
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10603
BRD-K87146261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28905
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.864162
increased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.430379
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86758
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
BRD-K30581008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11083
CPEB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17061
STAT3	ChEA Transcription Factor Targets	1.0	null
BRD-K69393995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07263
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07894
BRD-K57490754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25794
sirt3_21397863_brown_adipose_lof_mouse_gpl1261_gds4058	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.966824
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.39
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
TM4SF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13933
GSE129241_4_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMARCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82676
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12693
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCW-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12332
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-542-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Habenular trigone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
MAP1LC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71337
SETDB1	ChEA Transcription Factor Targets	1.0	null
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.83799
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45546
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90157
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.931051
endocrine gland cancer	GWASdb SNP-Disease Associations	1.0	0.385828
RUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80749
r3 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03347
Intermittent explosive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
SIN3A	ENCODE Transcription Factor Targets	1.0	null
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66777
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1758
klf11	GeneRIF Biological Term Annotations	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of cardiac morphology	HPO Gene-Disease Associations	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.3228
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283545
Prdm15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.848
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46224
CEBPD-23245923-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
kctd8	GeneRIF Biological Term Annotations	1.0	null
Zona fasciculata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60978
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65159
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03841
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.230382
BRD-K08754235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08057
Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95821
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF554	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89233
Anterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.026
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.51823
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
PRR29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47646
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106745
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33528
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327896
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.472
PrPC_KO_GDS4352_359_mouse_Developing hippocampus from adults (3-mo-old)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-A08759443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11368
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.451
BRD-K88016677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13764
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58441
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K81888673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70118
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1809
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
NCI-H226Br cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.139
EPHB2_drugactivation_228_GSE26523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.66629
UO31	BioGPS Cell Line Gene Expression Profiles	1.0	0.932003
EED	ChEA Transcription Factor Targets	1.0	null
translocator	GeneRIF Biological Term Annotations	1.0	null
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38521
increased body length	MGI Mouse Phenotype Associations 2023	1.0	null
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25356
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.31029
FLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74121
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K19264579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05489
Child Development Disorders, Pervasive	HuGE Navigator Gene-Phenotype Associations	1.0	null
BMI1	ChEA Transcription Factor Targets	1.0	null
Paraventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.148
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02719
hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230409
Sotos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
Vincristine	CTD Gene-Chemical Interactions	1.0	null
chromosome, centromeric region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.236
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07113
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.084156
radial deviation of finger	HPO Gene-Disease Associations	1.0	null
abnormality of the palate	HPO Gene-Disease Associations	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHOS2	DepMap CRISPR Gene Dependency	1.0	2.51634
Short Palm	DisGeNET Gene-Phenotype Associations	1.0	null
Corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.803
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47514
Orr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.798125
SIPA1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74174
PMC9240038-41467_2022_31337_MOESM5_ESM.xlsx-Sheet1-CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10833
KLF4	ChEA Transcription Factor Targets	1.0	null