association	dataset	threshold value	standardized value
structure	GeneRIF Biological Term Annotations	1.0	null
NOTCH1_Deficiency_GDS2848_635_mouse_Hair follicles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
A253	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48627
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.377485
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0143
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4801
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70466
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
SALL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484905
BRD-K06678077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51473
Cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
jvm13	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.554
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BRD-K76068355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31006
Peripheral Vascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K30173809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02646
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.802225
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8319
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891189
BRD-K56837922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5593
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.2595
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K92700781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.625
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	2.88009
BRD-K57782577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98802
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.08991
midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.637999
BRD-K07982814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47882
253JBV	CCLE Cell Line Gene Expression Profiles	1.0	1.72681
KMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31571
NR3C1	ENCODE Transcription Factor Targets	1.0	null
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
BRD-K49866832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37529
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.265
BRD-K72997741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3141
Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92913067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05041
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35243
BRD-K88739137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6887
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75253
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08554
BRD-K25081075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27265
Auxin efflux carrier complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.975882
Granuloma inguinale	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052975
Essential hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
BRD-K47349225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03608
GSE227592_9_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
BRD-K05804651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03601
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9382
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26539
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.102
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85827
SIRT1_KO_GDS4895_43_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4231
Phosphate	HMDB Metabolites of Enzymes	1.0	null
BIN67	DepMap CRISPR Gene Dependency	1.0	3.14238
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
Chlamydia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.249531
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00725
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
GSE243491_3_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73436
Edema	CTD Gene-Disease Associations	1.0	1.30177
Ribose phosphate diphosphokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
CHST7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98877
X-linked dominant hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
M059J	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gout	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K18724553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18427
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4214
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.15218
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.482844
conditions	GeneRIF Biological Term Annotations	1.0	null
TRIM21	Hub Proteins Protein-Protein Interactions	1.0	null
SUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	2.41431
TARDBP_02_116	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.81876
GSE207914_3_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.186
EP300	ENCODE Transcription Factor Targets	1.0	null
CTNNB1_OE_GDS4449_352_mouse_Embryonic kidney from E12.5 embryos (-catGOF-UB mutant)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061962
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.60151
769P	CCLE Cell Line Gene Expression Profiles	1.0	2.28941
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12845
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11230_KO_Cnot1_ERP104439	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.3624
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56998
CLPP_KO_GSE40207_397_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARA_agonist activation_GSE17250_475_mouse_Isolated hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
Perturb_11335_KO_Bmal1_SRP060296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.3527
Perturb_10322_KO_MYC_SRP310502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.38645
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8109
BRD-K95672449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15947
BRD-A84764193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38788
Hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.33722
CTIP_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
BRD-A14842104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10352
TK10	GDSC Cell Line Gene Expression Profiles	1.0	1.84074
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08691
Perturb_10700_OE_Yap1_SRP132526	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.65191
Kidney_CT1_Proximal Tubule Cell Epithelial Segment 3	HuBMAP ASCT+B Annotations	1.0	null
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75639
H3K9ac_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Perturb_9556_KO_IKKa_SRP111864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.54874
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.795
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11375
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98089
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92884779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55144
BRD-K95455263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35057
BRD-K88707941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64434
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
CLEC10A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00843205
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
SIRT1_KO_GSE28790_47_mouse_brain (3 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.066648
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7983
Apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.405
KURAMOCHI	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K17482962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60929
BRD-A67787745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60455
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.365819
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
BRD-K13226207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66144
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.55574
Phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44549496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81125
RCM1	DepMap CRISPR Gene Dependency	1.0	16.1184
BRD-K22915992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92286
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40621788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2586
BRD-K86065375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10747
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	1.38671
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055448
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55665639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08681
EB2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58771
Iron status biomarkers	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24145
HDAC1	ENCODE Transcription Factor Targets	1.0	null
gout	GeneRIF Biological Term Annotations	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.126
BRD-K92570288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86498
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.772
Sporozoan form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
BRD-K85456600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64071
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173832
GSE208254_3_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100350_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47893
BRD-K89724519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01015
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.99102
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056589
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49411
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.74537
Arthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
BRD-A16827030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59654
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5811610__F6	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-A55025683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10713
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86359
hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.418768
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.754
RHPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76349
BRD-K25525067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18763
BRD-K28983467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.514
AKR1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28876
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.79344
Type 2 diabetes mellitus_Renal Tissue_GSE642	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.90617
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Leukemia, Adult T Cell_Blood monocyte_GSE10789	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.978602
SETX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53163
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.92863
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1761
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2116
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94489736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15879
CRCGN015_HEPG2_48H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.03062
HCC2998	DepMap CRISPR Gene Dependency	1.0	4.67634
BRD-K81099637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.85054
BRD-K75164441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93844
MYC	ENCODE Transcription Factor Targets	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE200352_11_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KRAS.DF.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0808
BRD-K43548664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16201
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.724
BRD-A39660642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46113
K029AX	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75138
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83109105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88607
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51569
phosphate ion transport	GO Biological Process Annotations 2025	1.0	null
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19911
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97157
NCO2	CCLE Cell Line Gene CNV Profiles	1.0	1.51982
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29558
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.69315
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2359
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.194235
BRD-K04108962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43135
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80769
Liver Diseases	CTD Gene-Disease Associations	1.0	1.18816
Poisoning	CTD Gene-Disease Associations	1.0	1.52313
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33762
Perturb_15744_KO_Cyp4v3_SRP358013	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.54726
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.922308
Fetal Death	CTD Gene-Disease Associations	1.0	1.12495
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93442068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39687
CLPP_KO_GDS4791_543_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.058586
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02797
physiological	GeneRIF Biological Term Annotations	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891189
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
europeans	GeneRIF Biological Term Annotations	1.0	null
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Phimosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
ESR1-17901129-mouse liver-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K08940439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6038
SNU216	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50451
OE21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K55220938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19657
urate metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28996
BRD-K83952475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36482
BRD-K96218803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.1116
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.772
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94035
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.861725
HNF4A	ENCODE Transcription Factor Targets	1.0	null
BRD-K93998074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44137
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33633
Hyperplasia	CTD Gene-Disease Associations	1.0	1.73516
cellular process	GO Biological Process Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Perturb_12071_OE_Tfap2a_SRP067296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.71127
HEK-293A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
BRD-K91854399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15713
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.328
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12604
single-organism transport	GO Biological Process Annotations 2015	1.0	null
Musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
effect	GeneRIF Biological Term Annotations	1.0	null
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3325
CTSB	MSigDB Cancer Gene Co-expression Modules	1.0	null
BT16	DepMap CRISPR Gene Dependency	1.0	3.70518
BRD-K49507197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7257
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11194
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52221
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.357847
BRD-K05086663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23409
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.47786
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hereditary hypophosphatemic rickets with hypercalciuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.391
Down Syndrome_Fetus_GSE10758	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.81542
CRCGN008_HEPG2_24H:E15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26055
HCMV_24Hour_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59822
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21701
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43989
level	GeneRIF Biological Term Annotations	1.0	null
CLPP_KO_GDS4791_377_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K33061098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25977
azotemia	GWASdb SNP-Phenotype Associations	1.0	0.410844
Stratum intermedium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
Inner mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.472
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
NUDUL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63527
CTCF	ENCODE Transcription Factor Targets	1.0	null
TOP2B_drug inhibition_GSE1417_341_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K34447537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08483
TALH cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
MET_knockout_262_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.78653
BRD-K37459038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22837
BRD-A03182941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56233
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.750921
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.932682
sodium-dependent phosphate transport	GO Biological Process Annotations 2025	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95952081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.99575
Perturb_10873_KO_Slc25a34_SRP342539	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43187
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21675
BRD-K36941678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46706
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.389666
GSE172020_1_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.782298
Perturb_11302_KO_Bmal1_SRP060296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52104
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.30818
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
BRD-K26251149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00943
Coronary Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K83673542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46862
BRD-A20182314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54556
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.468535
lung cancer	GWASdb SNP-Disease Associations	1.0	0.343698
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4487
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8158
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI8226	DepMap CRISPR Gene Dependency	1.0	3.52239
Henles loop cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
CRCGN008_HEPG2_24H:O16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0528
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45234
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
BRD-K21176869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33375
genomewide	GeneRIF Biological Term Annotations	1.0	null
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14041
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64589
GNB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00478128
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21296995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18798
BRD-K90238417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0824
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-138	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98075
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7387
Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27406233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04917
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
Fatty Liver	CTD Gene-Disease Associations	1.0	1.7014
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.286
BRD-K19502817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58498
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17687
BRD-K90311252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38809
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.62472
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.438544
Odontoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.108
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4429
CRCGN014_HEPG2_3H:D12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0922
SH10TC	DepMap CRISPR Gene Dependency	1.0	6.44366
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EQ-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74439
MDAMB468	CCLE Cell Line Gene CNV Profiles	1.0	1.47918
BRD-K14706855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11582
Dementia	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066798
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43827
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K13110820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44145
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12604
BRD-A78982410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78815
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10546
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
renal cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Sporoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.6368
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08352
BRD-K80690345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15188
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900183
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13382
Urate levels in overweight individuals	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6834
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06321
BRD-K23280067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19847
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93172
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
BRD-K95935249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02955
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7996
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11240_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.15889
exporter	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89108431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3862
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848477
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.993373
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polynesian	GeneRIF Biological Term Annotations	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LQ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95763144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26335
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908972
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12317
LYRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59958
vascular disease	GWASdb SNP-Disease Associations	1.0	0.062306
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5849
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3951
Urate levels in lean individuals	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.504576
BRD-K82506716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49384
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.9194
BRD-K79555018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50389
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.55624
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7766
Fibrosis	CTD Gene-Disease Associations	1.0	1.01776
BRD-K73523821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60142
GSE207914_0_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A46778020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83746
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_11298_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.98345
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67950754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69526
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	0.938562
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.998
HCC38	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66022
BRD-K38345640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28197
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77072
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K83370434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06802
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.101661
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KMRC3	CCLE Cell Line Gene Expression Profiles	1.0	1.35394
BRD-K02118124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27128
BRD-K82562625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39394
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22912
Vitamin D-Dependent Rickets	DisGeNET Gene-Disease Associations	1.0	null
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87137
Gout	DisGeNET Gene-Disease Associations	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46071
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847459
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22667
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.817
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
BRD-K63410075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23449
BRD-K86002795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09945
BRD-K34209560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03658
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42271016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10099
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6665
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.43042
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
TEAD4	ENCODE Transcription Factor Targets	1.0	null
anion	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4728-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
BRD-K89719122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65455
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.809
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06715
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.899354
CCC5	DepMap CRISPR Gene Dependency	1.0	3.14114
DSTYK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23083
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	0.938562
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.039827
NCIH209	CCLE Cell Line Gene CNV Profiles	1.0	1.43702
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Sporozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.84679
phosphate transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
TT2609-C02	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urate transport	GO Biological Process Annotations 2023	1.0	null
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.184241
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79569
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.612
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896613
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ERBB2_knockdown_236_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.23838
BRD-K93186184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11609
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2024	1.0	null
SYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22533
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.699919
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.694
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.16701
BRD-A65592966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36465
GSE180525,GSE180528_2_v_3_tbx3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
EM2	CCLE Cell Line Gene CNV Profiles	1.0	1.95194
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20645
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22797212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09714
BRD-K89366259	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99796
EM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4488
alzheimer's disease	GAD Gene-Disease Associations	1.0	null
BRD-A12372458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92119
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.852431
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K06261202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00469
Root cap	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
Perturb_10828_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34648
sodium-dependent phosphate transport	GO Biological Process Annotations 2023	1.0	null
Lysosomal storage disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31509
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19612
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33505
Inappropriate ADH syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
BRD-K98408839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1881
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.92662
HCC70	DepMap CRISPR Gene Dependency	1.0	2.81067
BRD-K39546571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42495
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
BRD-K12064774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08978
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.06658
NR2F2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37579
NO-10	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.74601
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47888
lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059593
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
IL27RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00484105
BRD-K75724196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84123
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF1B_HNF1B	Rummagene Transcription Factor Associations 2026	1.0	null
Corpuscular Hemoglobin Concentration Mean	DisGeNET Gene-Phenotype Associations	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30337
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46071
MAP2K7	MSigDB Cancer Gene Co-expression Modules	1.0	null
nitrogen compound transport	GO Biological Process Annotations 2023	1.0	null
GOLGA8A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00446945
Serum alkaline phosphatase levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.73979
sodium-dependent phosphate transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K40418847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74758
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06185
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4286
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08894
PMC6858555-NIHMS1538428-supplement-3.xlsx-ST18-Unnamed_6_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38661
purine-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K95068765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51766
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K54898824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44263
BRD-K61315077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22219
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.009397
BRD-A93436351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39678
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03366
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78837609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01654
J82	CCLE Cell Line Gene CNV Profiles	1.0	1.82249
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056377
neurological	GAD High Level Gene-Disease Associations	1.0	0.293278
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
AIRE_KO_GDS2015_33_mouse_thymic epithelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
INSRR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00577657
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.43554
risk	GeneRIF Biological Term Annotations	1.0	null
BRD-K94775036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04383
BRD-K61124142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63609
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20519
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6307
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
Intelligence	DisGeNET Gene-Phenotype Associations	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.23666
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP3K10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28942
Dent disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0832
BRD-K13401825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52995
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1544
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65293
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7597
GSE246053_4_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
4-P-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01318
CEBPB_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.202
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIRT1_KO_GDS4895_410_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56139
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.40801
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE197564,GSE198512_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04192407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09879
GRHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63941
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79730625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07738
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
CRCGN015_HEPG2_48H:B21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07893
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.287
BRD-K89065802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20964
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23931
CRCGN008_HEPG2_24H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1886
CRCGN016_MCF10A.TP53.M_24H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19217
hyperuricemia	GWASdb SNP-Phenotype Associations	1.0	0.974864
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64589
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TXNDC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56768
abnormality of cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.292578
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13058
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29246335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94518
MAP3K14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53632
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
BRD-K56384677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36596
Serum metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.35229
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.21658
NCI-H1437	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55437
786	BioGPS Cell Line Gene Expression Profiles	1.0	1.95236
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F5-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10965_KO_Blk_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30484
Reticulate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.348
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
MDM2	MSigDB Cancer Gene Co-expression Modules	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.899303
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27783
BRD-K85440939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48449
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9048
BRD-K85901675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25732
BRD-K94801143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25564
BRD-K95688447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09551
Acute Myeloid Leukemia_LAML_TCGA-AB-2896-03B-01T-0751-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25986
Iron status biomarkers	GWAS Catalog SNP-Phenotype Associations	1.0	0.526478
Merozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.208
SUM185PE	DepMap CRISPR Gene Dependency	1.0	2.44538
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16852
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
erythrocyte indices	GAD Gene-Disease Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893908
QIMR-WIL	GDSC Cell Line Gene Expression Profiles	1.0	1.44431
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.17631
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.56294
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10989739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17014
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2859
H4C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30562
FOXP2	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75H-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.105
CHUK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93528
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	2.87395
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
CDH4	MSigDB Cancer Gene Co-expression Modules	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
CRCGN016_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46326
KURAMOCHI	CCLE Cell Line Gene CNV Profiles	1.0	2.39617
BRD-K09895564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0729
BRD-K80225716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52081
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7409
NCIH1341	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02041
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35413741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79759
kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160761
BRD-K48861177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17783
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.381
HEC1B	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.93692
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12265
Perturb_10823_KO_Xbp1_SRP262377	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.36886
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.046985
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
SPG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00491732
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	1.90408
monoatomic anion transport	GO Biological Process Annotations 2023	1.0	null
hsa-miR-3942-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-581	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Amino acid and oligopeptide SLC transporters	Reactome Pathways 2014	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10883
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17614
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8518-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30591
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.073844
LO68	DepMap CRISPR Gene Dependency	1.0	2.42874
decreased leukocyte cell number	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN017_MCF10A.TP53.M_24H:D22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4089
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
locus	GeneRIF Biological Term Annotations	1.0	null
BRD-K41853443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23863
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46594
SYK_druginhibition_284_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49896
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51409
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.638
suggested	GeneRIF Biological Term Annotations	1.0	null
BRD-A62469171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64952
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.0168
SBC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51545
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.176561
Perturb_9609_KO_Hmgcr_SRP301273	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.56476
PMC8563805-41598_2021_858_MOESM2_ESM.xlsx-Supplementary_Info_6-Gene_List_6_The_list_of_human_orthologs_of_the_downregulated_fly_DEGs_identified_from_TRAP_control_vs_PARIS_wild_type_comparison_ZNF746	Rummagene Transcription Factor Associations 2026	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.911903
BRD-K52119965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00153
BRD-K20271744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0582
phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.28294
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25201
MLLT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91003
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97013733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41248
CAL54	CCLE Cell Line Gene Expression Profiles	1.0	2.17393
BRD-K99827210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27478
ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.522
ion transport	GO Biological Process Annotations 2015	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	2.00689
GSE183251_7_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94722
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A14183911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39309
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.877253
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05727
purine-pyrimidine metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.154
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5065
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ChEA Transcription Factor Targets	1.0	null
BRD-K94469522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24968
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25201
GLRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98101
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44102
EFO21	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71038
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05041
NMCG1	DepMap CRISPR Gene Dependency	1.0	3.125
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.042443
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29109
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224970,GSE224971_1_v_0_sap30_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18822985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4763
BRD-K36171309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74899
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.879481
CL34	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90305
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46586
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16562
ARID3A	ENCODE Transcription Factor Targets	1.0	null
L-540	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72564
icSARS CoV_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.33881
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68547
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044159
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Parkinson Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K49932469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12004
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.67999
SU8686	CCLE Cell Line Gene CNV Profiles	-1.0	-2.55383
BRD-K62072978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21915
SMTNL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00632296
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05436
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18789
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRSF7_02_02	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.29342
SPHK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570313
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K77518191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03407
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4099-01A-02R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM183A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51833
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14957
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22718
BRD-K86911380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12824
A-CA-04-2009(H1N1)_3Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.42946
TMEM167A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56988
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91810283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12276
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.2941
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15561
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16578
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96079
OR2L3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510792
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
Perturb_11265_KO_Bmal1_SRP260650	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.8652
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.938937
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63333
BRD-K02473319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28785
BRD-K82882121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17054
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.874398
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.605591
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8411_KO_Srsf1_SRP252896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.08578
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48860650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61186
BRD-K91973560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43216
BRD-K51743001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94312
sodium-dependent phosphate transport	GO Biological Process Annotations 2015	1.0	null
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39702
BRD-K32983008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1363
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094066
LIPE_KO_GDS1318_501_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
Serum uric acid levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.129504
BL8232 (TOP3A)	NURSA Protein Complexes	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899725
Geep	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
RCC4	CCLE Cell Line Gene Expression Profiles	1.0	1.42503
Nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.516
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2392
PATU8902	DepMap CRISPR Gene Dependency	1.0	2.37006
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00545288
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47355
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
gout	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.995303
BRD-K33257311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44752
AP4B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83632
BRD-K27881972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36941
HNF4G_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung carcinoma	GWASdb SNP-Disease Associations	1.0	0.394356
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20519
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SKBR3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46038
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899725
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.39023
PC-14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATF2	MSigDB Cancer Gene Co-expression Modules	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K01534436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9375
ACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37575
BRD-A43135847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.74445
BRD-K11666748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26051
EIF2AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80688
CRCGN008_HEPG2_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1009
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847459
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68234
HAUS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26451
SERPINB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00556304
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A6JB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-A63342325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7551
BRD-K81288338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73373
WRL-68 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
Phosphoribosylpyrophosphate synthetase superactivity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.654
Adrenocortical carcinoma_ACC_TCGA-OR-A5LT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A954-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97368
CORL47	DepMap CRISPR Gene Dependency	1.0	3.79775
Uric Acid Measurement (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50696
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.354
Acute Myeloid Leukemia_LAML_TCGA-AB-2812-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51432
BRD-A47798787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4257
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2388
BRD-K61414850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35432
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00133
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85357344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0727
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905667
ATM_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K67592986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49149
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.248596
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63
C2BBE1	DepMap CRISPR Gene Dependency	1.0	2.68357
BRD-K80996561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53052
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K56179613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02825
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466498
Erythrocyte Indices	dbGAP Gene-Trait Associations	1.0	0.685324
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25145
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36172
BRD-K40602242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04296
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Major facilitator superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15629
ACHN	CCLE Cell Line Gene Expression Profiles	1.0	1.97139
Weight Loss	CTD Gene-Disease Associations	1.0	1.61621
BICR16	DepMap CRISPR Gene Dependency	1.0	2.35811
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5625
liver	GTEx Tissue Gene Expression Profiles	1.0	1.20559
hsa-miR-4666-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.122
BRD-K78252315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46529
BRD-K06146578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39576
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891878
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891189
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89455
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45229
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839203
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K25423830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03524
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hepa-1c1c7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.995303
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8852
Learning Disorders	CTD Gene-Disease Associations	1.0	1.13313
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
MAGEA8	MSigDB Cancer Gene Co-expression Modules	1.0	null
KYSE150	CCLE Cell Line Gene CNV Profiles	1.0	1.95785
Xanthinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
Spore wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.504
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4756
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.433
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848987
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
gout	GWASdb SNP-Phenotype Associations	1.0	0.974864
EJM	DepMap CRISPR Gene Dependency	1.0	2.58769
CEP164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93729
BRD-K49666076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46914
BRD-K76329122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17613
LB2241-RCC	GDSC Cell Line Gene Expression Profiles	1.0	1.77678
BRD-K14163107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40867
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OLIG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5036
BRD-A07195938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27324
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.426575
EB-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K79202867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48669
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40974
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848477
gout	GAD Gene-Disease Associations	1.0	null
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.73587
drofenine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96081
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.14409
BRD-K39499927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99663
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.225
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963927
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.76448
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYOC_OE_GDS1640_269_mouse_retina	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K94692455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83447
Apical plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Xanthinuria type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.228
J-774A.1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55332
Blood metabolite levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.740948
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01164
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99244
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tenofovir clearance in HIV infection	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35923751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56829
BRD-K34519525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40155
inorganic anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K75038114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13068
peripheral vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.438544
COLO824	DepMap CRISPR Gene Dependency	1.0	2.11315
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0223
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072543
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Steatotic liver disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
DBNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35873
BRD-K85527716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76016
Scleroderma_Fibroblast_GSE1724	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.6094
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
SP1	ENCODE Transcription Factor Targets	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.125086
BRD-K64264263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02801
BRD-K53752646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46799
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19516614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08484
PDHB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0036327
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.24
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37928
BRD-K00502656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11267
PMC12256341-mmc1.xlsx-ST12_-_Nearest_Genes-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17753780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56379
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5354
BRD-K07576726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78713
solute:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
serum uric acid	GAD Gene-Disease Associations	1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1057_KO_Bcl9/Bcl9l_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.2767
chr6_25844838_G_A_b38	GTEx eQTL 2025	1.0	2.07181
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9547
Urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.56191
PMC4224449-pone.0112193.s009.xlsx-PPI_MODULES_CLEAN_MAP_merg_OUT-Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
Mesophyll cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.471539
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.773174
HRPT-related hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
BRD-K29685390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5892
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
BRD-K65496998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11378
BRD-K76680796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59662
common	GeneRIF Biological Term Annotations	1.0	null
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	2.01388
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC4122637__F3	PFOCR Pathway Figure Associations 2024	1.0	null
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10339
BRD-A91823394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22211
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
SUDHL5	DepMap CRISPR Gene Dependency	1.0	2.23245
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61252
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heterochromatin island	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
BRD-K94018786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12939
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51446586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25355
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.788208
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464948
PMC3402799__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7222
BRD-K63436213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06683
VMRCRCZ	CCLE Cell Line Gene Expression Profiles	1.0	3.40786
BRD-K16937802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74362
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K99764436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30799
CALY	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551286
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K18296568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58537
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8014
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K05228434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11708
HOXA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74393
Alzheimer Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
hsa-miR-7	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NCIN87	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01209
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.04352
BRD-A05422420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12306
BRD-K90111788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56334
Papillary duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.42
Schizont	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
BRD-A86977540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16472
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.253
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4613
Liver Cirrhosis, Experimental	DisGeNET Gene-Disease Associations	1.0	null
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.22522
inorganic anion transport	GO Biological Process Annotations 2015	1.0	null
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-A84913188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28576
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1694
Inner medullary collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
Blood metabolite ratios	GWAS Catalog SNP-Phenotype Associations	1.0	1.21361
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28064
KNS-42	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
GSE149075_6_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease Progression	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K73427605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4489
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11876
BRD-K05118861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89631
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Red Blood Cell Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K37515001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3351
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.99501
Intrinsic component of mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.176
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	2.78854
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K41513047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45625
Tcf1_KO_GDS1473_307_mouse_Pancreatic islets	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2829
hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.745039
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87406
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064665
Autosomal dominant nonsyndromic deafness 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
BRD-K35341092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16234
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A24369193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38966
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.0194
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25308
H2AX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96163
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14476597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3119
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE197948_2_v_0_atp7b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLR21	CCLE Cell Line Gene Expression Profiles	1.0	1.44729
molecular	GeneRIF Biological Term Annotations	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04064
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
PMC10260405-41588_2023_1409_MOESM6_ESM.xlsx-ST12-Supplementary_Table_12_Most_likely_causal_genes_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
Hypertrophy	CTD Gene-Disease Associations	1.0	1.59404
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAGEA9	MSigDB Cancer Gene Co-expression Modules	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SHP77	DepMap CRISPR Gene Dependency	1.0	3.95926
BRD-K47794327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36308
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135468
Urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.332
BRD-K74445272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16329
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-O8-A75V-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88070373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31812
hsa-miR-2276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63127
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.953107
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.047895
SKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.85895
ursodeoxycholic acid_mus musculus_gpl6246_gse22608	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cystic Fibrosis_Lung_GSE3100	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.46322
BRD-K12884811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30094
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75067815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68411
BRD-A56427952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12759
arthritis	GWASdb SNP-Disease Associations	1.0	1.78086
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
F-actin capping protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.951
ACHN	GDSC Cell Line Gene Expression Profiles	1.0	2.96188
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0286
H3K27me3_Fetal Heart	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.412405
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0903
BRD-K14813771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05531
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69601
Red blood cell traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
BRD-K91419355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38827
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75776
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80308
PRDX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4375
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.726
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4867
decreases	GeneRIF Biological Term Annotations	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7335-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3833
MAP3K1_knockout_245_GSE39240	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.84765
FIBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36174
Major facilitator superfamily domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE160373_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3155	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
solute:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.127721
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01639343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42419
PTPRR	MSigDB Cancer Gene Co-expression Modules	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4662
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24721
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041521
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DB-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	6.73609
KLHL24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40915
BRD-K01734019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40785
FBLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67381
liver	HPA Tissue Gene Expression Profiles	1.0	1.29264
BRD-K60782883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53307
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2631
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.066394
GSE207914_5_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.21658
metal ion transport	GO Biological Process Annotations 2015	1.0	null
anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
NCIH2023	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66367
Kidney_CT1_Proximal Tubule Cell Epithelial Segment 3	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
BRD-K48299239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82688
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.6841
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
cation transport	GO Biological Process Annotations 2015	1.0	null
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal joint morphology	GWASdb SNP-Phenotype Associations	1.0	0.220049
BRD-K56427898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09862
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8402
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K83553001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61752
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
FUOV1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61787
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.7604
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01942
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1143	CCLE Cell Line Gene CNV Profiles	-1.0	-1.507
BRD-K14780713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14058
CRCGN015_HEPG2_48H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64502
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08939002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88472
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.642988
Bacterial Infection_Leukocyte - Monocyte - Macrophage (MMHCC)_GSE6435	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.16239
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065433
BRD-K07385991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1866
iron	GAD Gene-Disease Associations	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86726
organic anion transport	GO Biological Process Annotations 2025	1.0	null
HeLa-229 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10822
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058089
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05103
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
ESR1-17901129-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3731
NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06356885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2596
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
SNU1272	CCLE Cell Line Gene Expression Profiles	1.0	1.4547
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55069
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.228221
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11140_KO_Myc/Mlxipl_SRP148418	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.19081
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.635572
strongly	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891878
bone inflammation disease	GWASdb SNP-Disease Associations	1.0	1.67021
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97886
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Acute kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
BRD-K83010768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10602
BRD-K19159562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22338
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89347
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.52216
IGFBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6322
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.94324
localization	GO Biological Process Annotations 2015	1.0	null
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphogranuloma venereum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
TNFRSF10D	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531308
BRD-K64862162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27369
BRD-K82175530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52349
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A46566149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51947
BRD-K95500312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3152
MAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00430608
BRD-K13267677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17525
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6585
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.83402
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.438544
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.068353
abnormality of transition element cation homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.365189
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TGBC11TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9333
BRD-K97086564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08649
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44542
RAD51D	MSigDB Cancer Gene Co-expression Modules	1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8388
BRD-K87875370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1211
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3
CORL51	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58792
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QJ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3833
BRD-K94518115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46037
BRD-K24284160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17644
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19615
BRD-K91341416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9609
peripheral vascular diseases	GAD Gene-Disease Associations	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00595
BRD-K85627183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48704
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.160013
BRD-K15273135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05697
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8666
BRD-K60635455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54943
GSE152937_6_v_5_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77221872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12144
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059147
BRD-K73929798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18062
Axillary bud meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58469
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41091
Hereditary arterial and articular multiple calcification syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
STAT3	ENCODE Transcription Factor Targets	1.0	null
BRD-K48221699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26629
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.582
BRD-K51153795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07185
bone disease	GWASdb SNP-Disease Associations	1.0	0.942185
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81960205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58175
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.52157
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16613
Chromatin silencing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.138
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.161434
BRD-K64902833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45747
BRD-A60877539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75809
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	1.55036
Hypophosphatemic Rickets	DisGeNET Gene-Disease Associations	1.0	null
CAKI2	DepMap CRISPR Gene Dependency	1.0	3.91675
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
OVISE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47671
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE243491_3_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
BRD-K31806725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48679
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19721
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52139780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2297
Red blood cell traits	GWAS Catalog SNP-Phenotype Associations	1.0	0.369252
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44P-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
BRD-K06117861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.09624
BRD-A85028244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17166
H-EMC-SS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
BRD-K63024248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81177
JHOC5	CCLE Cell Line Gene Expression Profiles	1.0	1.85123
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13635
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
Carotid atherosclerotic plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06577
GSTM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.4829
BRD-K35404627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20362
Autosomal dominant hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
GSE131161_5_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
BRD-K59272984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24043
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18532
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.037
BRD-K98320707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09334
inorganic anion transport	GO Biological Process Annotations 2023	1.0	null
SKNSH	DepMap CRISPR Gene Dependency	1.0	6.08843
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fanconi renotubular syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
NQO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80167
Intelligence (MTAG)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.904576
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99097591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38323
Iron-Regulatory Proteins	dbGAP Gene-Trait Associations	1.0	0.866561
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45845
immune system disease	GWASdb SNP-Disease Associations	1.0	0.190915
BRD-K94378105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01273
phosphate ion transport	GO Biological Process Annotations 2023	1.0	null
CXCR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00486233
BHLHA15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9869
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRX_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.88461
BRD-A52893269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26962
Perturb_10323_KO_MYC/Setd2_SRP310502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.82576
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.054683
significance	GeneRIF Biological Term Annotations	1.0	null
review	GeneRIF Biological Term Annotations	1.0	null
BRD-K88658905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27707
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K67873600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00985
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
gout	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.78038
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.176894
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27414
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.838063
BRD-K23196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46651
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	7.63304
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3921
Refractive error	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.33979
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.49089
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.0189
HK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
BRD-K28932860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04615
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34889
CAMK4	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K28467592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83579
769-P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67284
KASUMI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62845
BRD-K37698302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04419
BRD-K25952063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1305
SCH	DepMap CRISPR Gene Dependency	1.0	2.30449
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83139
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15907
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.159
MDST8	DepMap CRISPR Gene Dependency	1.0	5.7815
BRD-A64237946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37958
Iron	dbGAP Gene-Trait Associations	1.0	0.796965
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99854
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
DNTTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16287
abnormality of iron homeostasis	GWASdb SNP-Phenotype Associations	1.0	1.35901
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
CRCGN015_MCF10A.TP53.M_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.094
phosphate ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
BRD-K71213946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07454
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.55206
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.4071
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.695
17009876-tableS3a	GeneSigDB Published Gene Signatures	1.0	null
OCI-LY-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20645
CA-SKI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Polycistic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38075
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
Serum Ferritin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043639
TC138	DepMap CRISPR Gene Dependency	1.0	2.13257
KNS62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36339
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.171005
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.92865
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4323
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.248905
THP1	DepMap CRISPR Gene Dependency	1.0	2.79893
Perturb_17251_KO_Il17ra_SRP069071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.52788
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.938808
FABP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78243
KYO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46719
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04367
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pork consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.01549
IGF1R_knockout_151_GSE32936	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.51723
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.291898
ZNF317	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5879
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28345
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	1.14713
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
PMC3402799__F2	PFOCR Pathway Figure Associations 2023	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.2154
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9383
Polycystic kidney disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
Extrachromosomal rDNA circle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.326
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.0575
Oily fish consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.41549
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52123365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65541
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
Iron levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.463473
BRD-K83183132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40365
LYRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48078
NCIH28	DepMap CRISPR Gene Dependency	1.0	3.03871
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08298
Galactokinase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
kidney	HPA Tissue Gene Expression Profiles	1.0	1.77017
schizophrenia	GAD Gene-Disease Associations	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05514
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061447
BRD-K12336887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31116
Bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
TNFSF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618872
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146074_9_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25097691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73498
Human - Kidney - L3 - Proximal Tubule Epithelial Segment 1	HuBMAP Azimuth Cell Type Annotations	1.0	null
BRD-K78960724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26044
SMARCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65296
KM12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85994
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54254
BRD-K91094364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20887
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12845
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
BRD-K80736363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8797
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
responsible	GeneRIF Biological Term Annotations	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.126
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K81200901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59144
SNRNP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33348
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
BRD-K19040998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93096
BRD-K47366416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50339
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.792
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.50751
GSE165274_1_v_2_poldip2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
SIRPD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00679153
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1317
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061158
STT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76733
BRD-A48478073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66063
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40628
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30812
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K63107801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34785
chloroxylenol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4094
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3155b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K66187822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11198
SNU1079	CCLE Cell Line Gene Expression Profiles	1.0	1.57806
Osteomalacia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.239
Bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0903
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5947
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33345
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_downregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
THRA	MSigDB Cancer Gene Co-expression Modules	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99854
BRD-K27226238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41302
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
LU165	DepMap CRISPR Gene Dependency	1.0	2.28198
BRD-K64536135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11112
Mitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.816
fructose	GeneRIF Biological Term Annotations	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041468
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8598
Uric Acid	dbGAP Gene-Trait Associations	1.0	1.55707
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.979
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A97G-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transferrin	GAD Gene-Disease Associations	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926565
Renal proximal tubule epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
BRD-K47801291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12997
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.18783
16790086-tableW1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K12524104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98331
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CALU3	CCLE Cell Line Gene CNV Profiles	1.0	1.42303
NCIH522	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
PMC5811610__F6	PFOCR Pathway Figure Associations 2024	1.0	null
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Shoot apical meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.160013
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17245631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83091
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11998
MED1_OE_GDS4846_11_human_LNCaP prostate cancer cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.83708
IL4	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K17175263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21989
PSME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07722
BRD-A75954196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33416
BRD-K06313694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32896
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.06032
BRD-K37760996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24238
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133896
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.428943
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEKTE	CCLE Cell Line Gene Expression Profiles	-1.0	-3.98437
promoter	GeneRIF Biological Term Annotations	1.0	null
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.88
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GB-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYO1	CCLE Cell Line Gene CNV Profiles	1.0	2.02147
Urate levels	GWAS Catalog SNP-Phenotype Associations	1.0	1.70747
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
variant	GeneRIF Biological Term Annotations	1.0	null
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11509
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6559
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79448
1-alkyl-2-acetylglycerophosphocholine esterase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
BRD-K48699175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37821
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13917
NEDD4L	Hub Proteins Protein-Protein Interactions	1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5907
BRD-K87776049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17226
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9061
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056144
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05436
epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391553
BRD-K23556321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51258
Organic anion transporters	Reactome Pathways 2024	1.0	null
NCI-H28	GDSC Cell Line Gene Expression Profiles	1.0	1.95731
BRD-K00551139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48308
15208663-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
transporter	GeneRIF Biological Term Annotations	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9774
BRD-K88281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20931
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6003
IFNA1	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K02274100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75093
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12441
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97748753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34952
OLIG3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4771
BRD-A78042852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88197
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847459
Proximal tubule cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
ZSCAN31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30356
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.176245
BRD-K77820762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56159
BRD-K05796207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39055
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.772
abnormality of ion homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.292578
PABPN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00734532
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.911034
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24779
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16428
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13275
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.217553
BRD-K43989220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45327
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38224
BRD-K77403813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08131
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K0-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS294T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25934
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
U118MG	DepMap CRISPR Gene Dependency	1.0	2.74497
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
symporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K75038426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37846
lung adenocarcinoma	GWASdb SNP-Disease Associations	1.0	0.84116
Gitelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
FAM3C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00359183
Perturb_10852_KO_Smyd3_SRP057101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.19449
Coronary Artery Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
TP53_01_10	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58309
BRD-K55927371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68199
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.05119
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vacuole-isolation membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.6765
urate transport	GO Biological Process Annotations 2025	1.0	null
BRD-K82754613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50084
KCNA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555222
BRD-K76114475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5991
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36424
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5
transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.106
KARPAS-422	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS114	CCLE Cell Line Gene CNV Profiles	1.0	1.3353
SH2D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6301
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.742
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284607
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913904
Perturb_15771_KO_Nrl_SRP219918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.85243
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6608
SMC loading complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
NCIH28	CCLE Cell Line Gene Expression Profiles	1.0	2.31242
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.995303
BRD-K05304510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54515
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.80017
Lung squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
Neoplasms	CTD Gene-Disease Associations	1.0	1.35213
BRD-K29547381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62172
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89347
GCIY	CCLE Cell Line Gene Expression Profiles	1.0	1.60901
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.995303
dactinomycin_homo sapiens_gpl7172_gse12459	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.44
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.60292
NCIH2087	CCLE Cell Line Gene Expression Profiles	-1.0	-2.75367
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847459
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94045
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69046
Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.35229
increased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10171338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03224
Human - Kidney - L2 - Proximal Tubule Epithelial Segment 1	HuBMAP Azimuth Cell Type Annotations	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57639176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32266
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09488
GSE203308_6_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66690073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19044
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.995303
EMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49071
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43125
Lung squamous cell carcinoma_LUSC_TCGA-22-1000-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98856654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46844
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
Trophozoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.292
Ookinete	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.35793
BRD-K12306640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26952
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
HSD17B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68897
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.228221
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.04533
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuroblastoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.32255
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074489
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044544
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21924
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24426
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06926
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56472
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93855
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85705
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UM-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.21924
BRD-K97452545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18218
BRD-K94306568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48673
BRD-K74382273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25514
BRD-A07214340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23263
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.402
CRCGN015_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5926
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834257
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52307
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61431
Perturb_10861_KO_Med23_SRP027536	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.22114
MKN28	GDSC Cell Line Gene Expression Profiles	-1.0	-1.88907
clear	GeneRIF Biological Term Annotations	1.0	null
BRD-K86600397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81596
VA-ES-BJ	GDSC Cell Line Gene Expression Profiles	1.0	2.19424
FTC238	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46195
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13021
BRD-K17790291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0144
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.880226
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4756
BRD-K96265882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08353
HCC-56	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K55638368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23496
icSARS CoV_12Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.94878
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K81995936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30541
BRD-K69453385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73349
phosphate ion transport	GO Biological Process Annotations 2015	1.0	null
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43549
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
IL21_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08202
BRD-K36208388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06292
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intrinsic component of mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K36135420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63119
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.870006
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acyclovir	CTD Gene-Chemical Interactions	1.0	null
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1983
SNUC1	DepMap CRISPR Gene Dependency	1.0	4.56106
Myosin IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
BRD-K45471346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06525
BRD-A68949340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16225
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050311
NOS2	MSigDB Cancer Gene Co-expression Modules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
under	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438356
769-P	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847459
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47678
cloning	GeneRIF Biological Term Annotations	1.0	null
Kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.338
BRD-K32146668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07889
BRD-K80766355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20087
BRD-K73899643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18546
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRD-K02934881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12297
DDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93728
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHTF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K22377875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43649
BRD-K31908823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08011
SALL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97003
cancer	GWASdb SNP-Disease Associations	1.0	0.043099
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450657
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DES_KO_GDS4804_171_mouse_young skeletal muscles	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Iron Level Result	DisGeNET Gene-Phenotype Associations	1.0	null
uric acid	GAD Gene-Disease Associations	1.0	null
BRD-K88997070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2075
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosome 15q11.2 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
TUHR14TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.64071
NCI-H2141	GDSC Cell Line Gene Expression Profiles	1.0	1.44964
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-K37588779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81486
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K35681049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27976
SKNMC	DepMap CRISPR Gene Dependency	1.0	2.60011
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03858
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X2-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K39267096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02576
BRD-K75900952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13648
BRD-K82194980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02359
BRD-K62068620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13897
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40012
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35425
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90944
SPSB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07183
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.45215
LU-135	COSMIC Cell Line Gene Mutation Profiles	1.0	null
linked	GeneRIF Biological Term Annotations	1.0	null
CTAGE15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32053
A704	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73897
GSE182179_5_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.32192
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32249
BRD-K54260552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08134
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06743
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02610196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99867
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.186
BRD-K88070218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79741
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CRCGN014_HEPG2_3H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04846
ZEB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organic anion transporters	Reactome Pathways 2014	1.0	null
excretion	GeneRIF Biological Term Annotations	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104358
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17772
ATP-binding cassette (ABC) transporter complex, transmembrane substrate-binding subunit-containing	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.06
Myosin I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.285
ATP1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05511
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.79123
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87378
Obesity, Morbid	HuGE Navigator Gene-Phenotype Associations	1.0	null
midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442578
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.034
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.35088
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A6C9-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4087
FSHR	MSigDB Cancer Gene Co-expression Modules	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.46827
mineral metabolism disease	GWASdb SNP-Disease Associations	1.0	0.498333
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.177
Coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
Inflammation	CTD Gene-Disease Associations	1.0	1.96536
Microneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45893
Elementary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2629
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05756
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-RXRA_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A67521865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79508
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891878
BRD-A78355490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38953
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STK24	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473078
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
Disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.43061
Cholangiocarcinoma	CTD Gene-Disease Associations	1.0	1.03122
Body composition traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.22218
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74664
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDZK1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2847
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40781
Chang cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
BRD-K45631723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14084
Spastic tetraplegia, thin corpus callosum, and progressive microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Acute Myeloid Leukemia_LAML_TCGA-AB-2921-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
anion transport	GO Biological Process Annotations 2015	1.0	null
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53735
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94589
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.61492
urate metabolic process	GO Biological Process Annotations 2025	1.0	null
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	1.9039
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848477
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.19213
arthritis	GWASdb SNP-Phenotype Associations	1.0	0.255496
CLPB	Hub Proteins Protein-Protein Interactions	1.0	null
Glucose transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.964
BRD-K46269666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81203
parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.27794
load	GeneRIF Biological Term Annotations	1.0	null
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
dentate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271952
Mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.477
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7242
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.29129
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.305726
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
Urinary metabolite modules (eigenmetabolites) in chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.70458
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15145
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral Amyloid Angiopathy	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K60337516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46119
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.30359
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27951
BRD-K09378334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6157
BRD-K21409337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1531
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.874327
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	1.30968
SIRT1_KO_GDS3666_295_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-299-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
blood cells	GAD Gene-Disease Associations	1.0	null
KMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.44527
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.154
BRD-K61039403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65238
PMC9130782-Table_3.xlsx-downregulated-ZNF366_ZNF366	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92607052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96063
BRD-K59049340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05925
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77191
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.00761
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44346
BRD-K99690279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00599
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91767
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45097650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11416
BRD-A37105798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29348
BRD-K32205799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08796
CRCGN017_MCF10A.TP53.M_24H:I01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2365
serum markers of iron status	GAD Gene-Disease Associations	1.0	null
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.106121
Potassium	CTD Gene-Chemical Interactions	1.0	null
Neuropsychological Tests	HuGE Navigator Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A551-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.311087
Sjogren'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6013
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.908972
BRD-K95735171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28111
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.951
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.37735
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV3-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14868348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0972
BRD-K94514173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2354
BRD-K12784613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86933
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
AVPR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584559
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0222
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054477
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV2-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158815_5_v_0_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE160373_5_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97242998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8657
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.208
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	2.78131
NCCIT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.742
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A80705936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.78606
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Parathyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70762
IMR32	DepMap CRISPR Gene Dependency	1.0	3.73894
Fish- and plant-related diet	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.81549
Perturb_12556_KO_Sirt6_SRP302465	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.39081
GSE172020_1_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.620954
hsa-miR-197	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K47285393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56018
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K82324807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16825
Inherited metabolic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
BRD-K82217056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42873
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05365
urate	GeneRIF Biological Term Annotations	1.0	null
sodium:phosphate symporter activity	GO Molecular Function Annotations 2025	1.0	null
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0601
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MED27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70863
BRD-K13086002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20132
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4318
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10601
Serum uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.9
monoatomic ion transport	GO Biological Process Annotations 2023	1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	2.21614
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22595044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55428
LN340	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0844
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.95765
cldependent	GeneRIF Biological Term Annotations	1.0	null
arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.895
gainoffunction	GeneRIF Biological Term Annotations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46191
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84708
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5245
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.95108
decreased leukocyte cell number	IMPC Knockout Mouse Phenotypes	1.0	null
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4673
BRD-A64091909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18304
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25351
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54991
Heart Diseases	CTD Gene-Disease Associations	1.0	1.39619
BRD-K51054674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06282
chr6_25829810_C_A_b38	GTEx eQTL 2025	1.0	1.34186
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46156
BRD-A57474391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14688
Arsenic	CTD Gene-Chemical Interactions	1.0	null
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.172106
polyspecific	GeneRIF Biological Term Annotations	1.0	null
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
496100408_PCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04302
GSE195568_6_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45974539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02114
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H522	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.37572
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
BRD-K22383829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07381
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.365193
Uric acid levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.793579
BRD-K97241181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72296
GSE243491_1_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190947_2_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hepatobiliary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.458759
BRD-K31783598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39333
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52317
BRD-K81246784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11958
Carbon phosphorus lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
Familial juvenile hyperuricemic nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.87
16498405-TableS4	GeneSigDB Published Gene Signatures	1.0	null
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21269
PMC4122637__F3	PFOCR Pathway Figure Associations 2023	1.0	null
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.938347
BRD-K97869597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75531
BRD-K01709173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00448
psych	GAD High Level Gene-Disease Associations	1.0	0.295739
Perturb_3806_KO_Ptpn2_ERP124267	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.63432
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.42004
Toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
BTNL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00590636
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
BRD-K60653414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07865
inorganic anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Extrachromosomal DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.878
SEPTIN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44267
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5296
BRD-K14233531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67881
PMC10537816-12967_2023_4509_MOESM1_ESM.xlsx-ST18-Unnamed_4_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25791914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1289
Perturb_16533_KO_Cdk8_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Renal proximal tubule epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.887
KDM5B	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.011
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5405
OK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059472
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61648
KMS20	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65362
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03858
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K19652287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09866
Necrosis	CTD Gene-Disease Associations	1.0	2.1452
Gout	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
MYC_KD_GSE22139_685_human_medulloblastoma	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.502419
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07152
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Urinary metabolite levels in chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.70458
EBF1	ENCODE Transcription Factor Targets	1.0	null
underexcretion	GeneRIF Biological Term Annotations	1.0	null
humans	GeneRIF Biological Term Annotations	1.0	null
Sodium	HMDB Metabolites of Enzymes	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20645
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10075
A704	GDSC Cell Line Gene Expression Profiles	1.0	2.59233
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95941120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0629
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53589
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.78364
Perturb_11333_KO_Bmal1_SRP060295	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.73833
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13796
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESR1	ChEA Transcription Factor Targets	1.0	null
BRD-K54132860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49648
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77875
salivarygland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
Rickets, X-Linked Hypophosphatemic	DisGeNET Gene-Disease Associations	1.0	null
Hemocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84396
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08871
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3505
BRD-K57778236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06177
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40323
NB14	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45529
PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inorganic anion transport	GO Biological Process Annotations 2025	1.0	null
HEC1A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77742
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
RAD51D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
BRD-K52130884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14529
Gonadal Disorders	CTD Gene-Disease Associations	1.0	1.04163
BRD-K76353834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47501
BRD-A47109850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57242
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.176215
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.052968
Perturb_11251_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.4926
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46622
BRD-K45428339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29087
RAB3A_Mutation - D77G point mutation_GDS2482_702_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K04628654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37119
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ENKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10065
BRD-K63856509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04362
renal	GAD High Level Gene-Disease Associations	1.0	0.295739
BTN3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58781
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7767
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.94492
IL15_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501174
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Squamous cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
Arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
Hip circumference adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
BRD-K04562748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04686
A498	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Rett Syndrome_frontal cortex_GSE6955	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.85674
NCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68926
BRD-K07565511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70798
BRD-K67591072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.062
BRD-K06863452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70122
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13938991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.44165
Nephrolithiasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.742
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K03902789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29917
SNU46	DepMap CRISPR Gene Dependency	1.0	2.01477
RETREG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51505
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4053969-gb-2013-14-7-r81-S3.XLSX-YB1-targeted-genes-gene_YBX1	Rummagene Transcription Factor Associations 2026	1.0	null
COLO792	CCLE Cell Line Gene CNV Profiles	1.0	1.35427
PMC12008806-mmc13.xlsx-ST12-Unnamed_37_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.086232
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.982913
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995619
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.4174
organic anion transport	GO Biological Process Annotations 2023	1.0	null
Na-dependent inorganic phosphate cotransporter	InterPro Predicted Protein Domain Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JHU-029	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K17474512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2791
BRD-K92644013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25514
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90769476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42508
PMC8260656-41467_2021_24380_MOESM4_ESM.xlsx-ERG_EZH2-ENHANCED_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01217
BRD-K91235484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31151
Gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
eltanolone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25604
CAL-54	GDSC Cell Line Gene Expression Profiles	1.0	2.04491
BRD-A55063801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19841
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K35230457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81303
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
Hyperhomocysteinemia	DisGeNET Gene-Disease Associations	1.0	null
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2033
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
iron metabolism disease	GWASdb SNP-Disease Associations	1.0	1.51254
BRD-K33767223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15197
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HE-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.19835
BRD-A05456882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04429
Hydroxyisourate hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.879
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055166
BRD-K36168475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94539
BRD-K31372389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33495
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.7903
BRD-K11419664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59384
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5Q5-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3521
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes Mellitus, Type 2	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57138
BRD-K19118372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43868
BRD-K63743653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0124
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4165
icSARA deltaORF6_54Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.23533
Xanthinuria type I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.287444
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.33536
BRD-K88292241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04753
Blood Cells	dbGAP Gene-Trait Associations	1.0	0.106416
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1098
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.15
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67338
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72152
MAFK	ENCODE Transcription Factor Targets	1.0	null
BRD-K46560430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47429
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8509
FGF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61369
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7949
General cognitive ability	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.922185
BRD-K69468381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35823
BRD-K44856541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11363
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14485
fatty liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.177851
Neurological pain disorder_CNS - Spinal Cord (MMHCC)_GSE18803	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-3.8092
gout	GWASdb SNP-Disease Associations	1.0	2.78112
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07634
HMG20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91977
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
observed	GeneRIF Biological Term Annotations	1.0	null
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K70057550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.0519
Siphon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
impairment	GeneRIF Biological Term Annotations	1.0	null
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34024207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62823
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mineral metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
Renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
Apicoplast	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
Hyperlipidemias	CTD Gene-Disease Associations	1.0	1.14302
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hyperbilirubinemia	GWASdb SNP-Phenotype Associations	1.0	0.758275
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.995303
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0166
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38136
Death	CTD Gene-Disease Associations	1.0	1.17959
BRD-K17606413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1179
Renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CDKN2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513543
BRD-K21753319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18959
Mean Corpuscular Volume (Result)	DisGeNET Gene-Phenotype Associations	1.0	null
NCIH2172	CCLE Cell Line Gene Expression Profiles	-1.0	-2.46138
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10737
BRD-K29975122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07967
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.702713
GSE84922,GSE84924_0_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
monoatomic ion transport	GO Biological Process Annotations 2025	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sclerenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40115
habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.745039
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08352
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.073084
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31390971	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2949
CLPP_KO_GSE40207_381_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-3194-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4172
PMC8640960__F3	PFOCR Pathway Figure Associations 2024	1.0	null
SW1710	CCLE Cell Line Gene Expression Profiles	1.0	1.74028
THPO	MSigDB Cancer Gene Co-expression Modules	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880792
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.02379
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7088
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059869
Perturb_10899_KD_Mdr2_SRP055450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.68403
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K60123410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00184
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.554034
BRD-K92524823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0786
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.889965
Hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
kidney	GTEx Tissue Gene Expression Profiles	1.0	2.14024
ZFX_KO_GDS2718_151_mouse_hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
BRD-K79561909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35336
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE200352_11_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Uric acid nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
CNNM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88842
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34569
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91406875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29315
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
BRD-K37262603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33306
H2AC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00456581
BRD-K69790201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23231
BRD-K32431589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42026
subgroups	GeneRIF Biological Term Annotations	1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.194235
PAX7	MSigDB Cancer Gene Co-expression Modules	1.0	null
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23429
BRD-K17233342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7907
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05896
Perturb_9261_KO_Ifng_ERP010742	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.84867
BRD-K90693562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50294
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
Perturb_10834_KO_Xbp1_SRP197108	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.95287
S100A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51074
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of nitrogen compound homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.367655
Perturb_15759_KO_Msi1_SRP353788	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.87295
SIRT1_Deficiency_GDS4895_316_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1005
BRD-K51515697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81177
Urate levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.6301
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.995303
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91696
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.364
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.594
CRCGN015_MCF10A.TP53.M_24H:B24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.44985
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Gout	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.044
PRR14L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83665
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A06232236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11778
Intestinal juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
MESP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13484
Finding Of Mean Corpuscular Hemoglobin	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.160264
BRD-K73337367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19352
Lung non-small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848477
PMC4975902-12864_2016_2842_MOESM12_ESM.xlsx-targets_of_IRF8_in_NSCLC-COX7C_IRF8	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CLPP_KO_GDS4791_108_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K22537050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02581
MYO1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76691
Tachyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.462
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316951
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66838288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31378
e2f1_21245101_mmtv-myc_lof_mouse_gpl8321_gds4094	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.381115
BRD-K40221630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17731
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14971
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13888
Genetic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
BRD-K39979888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07352
GSE188870,GSE188871_4_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11504
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76976
ZIC2_01_121	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.69162
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9441
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97368
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24426
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415814
CRCGN017_MCF10A.WT.HP_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6326
Perturb_11275_KO_Bmal1_SRP337469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.18617
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.10665
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
AR4-2J cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
FAM76B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57997
17009876-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
hematological	GAD High Level Gene-Disease Associations	1.0	0.305726
NB1	DepMap CRISPR Gene Dependency	1.0	5.58877
sodium ion transport	GO Biological Process Annotations 2015	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
Ferritin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K26233698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28917
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9318
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51049
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RZ-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07473245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01894
NCI-H841	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KU812	DepMap CRISPR Gene Dependency	1.0	7.47931
Hemochromatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992403
BRD-K92904754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89543
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Osmiophilic body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.513
SPPL2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06208
BRD-K39131701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40074
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27817
ELP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84454
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47033
bilirubin metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.86494
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25351
POLR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIN87	DepMap CRISPR Gene Dependency	1.0	8.00991
SUPT3H	MSigDB Cancer Gene Co-expression Modules	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8305
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915654
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
NP8	DepMap CRISPR Gene Dependency	1.0	2.38834
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3375
RPS6KA5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609502
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.972909
BRD-K32021110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03905
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2014	1.0	null
BRD-K53343197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14282
BRD-K90902537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97559
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRO-AP2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K93127164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09948
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1682
non-small cell lung carcinoma	GWASdb SNP-Disease Associations	1.0	0.459072
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.9
hsa-miR-484	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.19662
CRCGN015_HEPG2_48H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20227
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.63676
RENT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88197
BRD-K66016089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18088
brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.426318
HNRNPLL_02_125	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.61471
BRD-K14258088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42316
hsa-miR-3173-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Iron Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25351
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.0196
BRD-K44537081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54473
BRD-K83049611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02726
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16613
BRD-A29371732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78694
BRD-K61022988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08432
BRD-K80851151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74482
BRD-K98355012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08469
BRD-K20024676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64292
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135174
BRD-K33770771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1994
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.698373
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCT15	BioGPS Cell Line Gene Expression Profiles	1.0	1.56486
PMCH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593223
BRD-K06250424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01564
253J	CCLE Cell Line Gene Expression Profiles	1.0	1.6756
inherited metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.20212
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891189
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occurrence	GeneRIF Biological Term Annotations	1.0	null
BRD-K79267333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67064
PMC12742282-TRA-27-e70025-s001.xlsx-Table_S3A_AP1_gamma_IPs-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K40923781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69538
BRD-K08179047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71096
CORL105	DepMap CRISPR Gene Dependency	1.0	2.65209
BRD-K35288606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49193
BRD-K68884923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17898
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.84508
DBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99375
BCL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11524
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0336
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
SKGI	DepMap CRISPR Gene Dependency	1.0	2.19481
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
genotype	GeneRIF Biological Term Annotations	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352227
Polar tube	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.537
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bradyzoite	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880792
Lipid storage disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.557
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.94385
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7787
CLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05811
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.62938
sodium:phosphate symporter activity	GO Molecular Function Annotations 2023	1.0	null
nitrogen compound transport	GO Biological Process Annotations 2025	1.0	null
X-linked recessive hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
NR3C1_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6138
iron metabolism disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.311576
Primary Gout	DisGeNET Gene-Disease Associations	1.0	null
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19015
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.304771
BRD-K96575636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21771
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Lesch-Nyhan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.152
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.49991
BRD-K17610834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35028
iron-regulatory proteins	GAD Gene-Disease Associations	1.0	null
hsa-miR-3678-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	2.65453
Transferrin	dbGAP Gene-Trait Associations	1.0	0.552134
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1913
BRD-K94353570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36421
HNF4G	ENCODE Transcription Factor Targets	1.0	null
BRD-K48448518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6001
496100375_FWM_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.00893
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
third	GeneRIF Biological Term Annotations	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A95442017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02594
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040646
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
BRD-K00377328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46921
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.968
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69215
T-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BTK_mutant_1_GDS1346	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.621239
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.51549
SUDHL6	CCLE Cell Line Gene CNV Profiles	1.0	2.05894
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.01324
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Congenital toxoplasmosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
BRD-K00685640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29916
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	1.95816
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891189
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19731191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31845
BRD-A06149038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18365
disease	GWASdb SNP-Disease Associations	1.0	0.141303
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44934
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5448
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.117
Perturb_9562_KO_Ogt_SRP110508	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.7629
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6578
phosphate ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9707
BRD-K85275903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55248
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07914
BRD-K01182779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8972
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973354
BRD-K97395479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61989
BRD-K95575699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27594
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96463
BRD-K98465548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13874
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE238116_3_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
renal	GeneRIF Biological Term Annotations	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44346
BRD-K20846358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47826
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47673
BRD-K49401787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62648
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29915
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15460257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56884
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
BRD-K81804676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98224
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041495
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.649
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
BRD-K97256018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.88848
GSE171269_1_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PKIB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00510591
DUSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57228
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.268958
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
Uric acid urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.248596
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.251934
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
membrane	GO Cellular Component Annotations 2015	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64173373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27054
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.411492
MSR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00614131
BRD-K14961381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06303
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11270_KO_Bmal1_SRP337469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44196
GSE70499_5_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null