association	dataset	threshold value	standardized value
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22779
Autosomal recessive nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.441
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48372
PMC11551338-pnas.2411189121.sd01.xlsx-PXR-Unnamed_0_NR1I2	Rummagene Transcription Factor Associations 2026	1.0	null
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
Medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.229
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.75371
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052644
NIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30443
decreased exploration in new environment	IMPC Knockout Mouse Phenotypes	1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
DEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.064
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.711
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41879
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7062
synaptic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Autosomal recessive nonsyndromic deafness 91	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32024
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66007
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.57141
MAGEB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42601
PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-Unnamed_0_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
biliary cirrhosis	GWASdb SNP-Phenotype Associations	1.0	1.11716
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14151
Interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.796
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
Striatonigral neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
explain	GeneRIF Biological Term Annotations	1.0	null
cochlear ganglion degeneration	MGI Mouse Phenotype Associations 2023	1.0	null
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36064
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.567626
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7391
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63681
abnormal neurotransmitter uptake	MPO Gene-Phenotype Associations	1.0	null
coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Synaptic vesicle pathway	WikiPathways Pathways 2024	1.0	null
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47254
Prostate adenocarcinoma_PRAD_TCGA-EJ-5498-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5823
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.671
abnormal behavioral response to xenobiotic	MPO Gene-Phenotype Associations	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32134
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15564
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Congenital Deafness	DisGeNET Gene-Disease Associations	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
SH3BGRL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3291
synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lung Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormal cochlear inner hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
Stereocilia tip link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.021
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34224
UMUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99869
TMEM88_KD_GSE43805_682_human_hES cells differentiated along the cardiac lineage	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.840281
Hemorrhage	CTD Gene-Disease Associations	1.0	1.04314
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848789
pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295297
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.144
YPEL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98507
CLDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08426
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.02268
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46097
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24603
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4348
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Catecholaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.521
portion	GeneRIF Biological Term Annotations	1.0	null
GSE185944_2_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
Perturb_10720_KO_Setd2_SRP220107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.75758
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89598
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06946
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.256
posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86339
DPPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63299
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.802
Habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal neuron physiology	MPO Gene-Phenotype Associations	1.0	null
lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070606
astroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06734
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840045
impairment	GeneRIF Biological Term Annotations	1.0	null
Perturb_11110_KO_Tsc1_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.1647
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10739_KD_Ddx3_SRP324914	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.95827
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221521
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063083
HCC1187	DepMap CRISPR Gene Dependency	1.0	5.79813
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75724
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48463
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus preopticus periventricularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7278
abnormal cochlea morphology	MPO Gene-Phenotype Associations	1.0	null
Carcinoma, Squamous Cell	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE217115_2_v_4_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04664
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GABA-ergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.051
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36412
l-alpha-amino acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
seizures	MPO Gene-Phenotype Associations	1.0	null
abnormal synaptic glutamate release	MPO Gene-Phenotype Associations	1.0	null
GSE224877_3_v_0_pctp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.940938
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.44733
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.891
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BPH1	DepMap CRISPR Gene Dependency	1.0	6.08256
Cholinergic interneuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14373
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312595
Low density lipoprotein cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.01549
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18469
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89918
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.918
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9685
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.689
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10647
ZDHHC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00998
Perturb_11297_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7833
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24113
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66711
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spastic tetraplegia, thin corpus callosum, and progressive microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13858
hsa-miR-3659	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
ING4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66328
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1292
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00243
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898331
h9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314046
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.353
superficial mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55384
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.115227
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183599
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045788
Autosomal recessive nonsyndromic deafness 93	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.988336
exocytic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal lymph node morphology	MGI Mouse Phenotype Associations 2023	1.0	null
NPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30704
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.901811
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044816
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00676
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant nonsyndromic deafness 24	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.639
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16363
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
L-glutamate transmembrane transport	GO Biological Process Annotations 2023	1.0	null
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40322
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4978
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64929
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36831
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02021
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23408
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart Failure	CTD Gene-Disease Associations	1.0	1.04978
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immune system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
Vestibular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
PMC9810646-41598_2022_27273_MOESM1_ESM.docx-1-ZNF786_ZNF786	Rummagene Transcription Factor Associations 2026	1.0	null
synaptic vesicle cycle	GO Biological Process Annotations 2023	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Paraventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.811
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23421
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02571
impaired hearing	MPO Gene-Phenotype Associations	1.0	null
vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE212893_2_v_3_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9692_KD_TCF4_SRP188467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.07258
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.364
Nicotine addiction	KEGG Pathways 2026	1.0	null
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50366
PMC8640960__F3	PFOCR Pathway Figure Associations 2024	1.0	null
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.641
Cerebellar mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.662
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
Lateral entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
synaptic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.079
monoatomic ion transport	GO Biological Process Annotations 2023	1.0	null
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56579
GSE125007,GSE125008_1_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19945
acidic amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Electrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14791
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
Cochlear hair cell ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.6558
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.997
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
hsa-miR-1261	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.381199
Ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.729
hsa-miR-4328	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
Cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GSE129389_0_v_7_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834451
MHHES1	CCLE Cell Line Gene Expression Profiles	1.0	1.42409
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95514
amygdaloid complex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33399
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88194
Distal axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.72
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050818
SLC41A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57976
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.94905
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70165
MAPK1_knockdown_45_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.75231
GSE158815_1_v_0_trib1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.30382
muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070136
Lung adenocarcinoma_LUAD_TCGA-05-5423-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Ventral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
Septal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
refractive error	GWASdb SNP-Disease Associations	1.0	0.39593
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
Lattice corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
Outer ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
NAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10123
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99512
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07762
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893712
glutamate	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00925
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25217
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91312
hsa-miR-3154	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20544
membrane part	GO Cellular Component Annotations 2015	1.0	null
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
fetal	GeneRIF Biological Term Annotations	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058452
Exocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92174
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.773296
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919255
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14691
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35154
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1132
PGP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47798
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79132
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.564035
monoatomic anion transport	GO Biological Process Annotations 2023	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54781
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
GSE223008_11_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glutamatergic synapse	KEGG Pathways 2026	1.0	null
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.939
Nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.76
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4204
NUDT16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57288
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal inner ear morphology	MPO Gene-Phenotype Associations	1.0	null
TOMM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61215
hsa-miR-3146	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.634
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054998
MITD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84647
Sensory ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45237
KMRC3	DepMap CRISPR Gene Dependency	1.0	2.30981
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
acidic amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27199
Hypertension	CTD Gene-Disease Associations	1.0	1.28364
COR-L303	COSMIC Cell Line Gene Mutation Profiles	1.0	null
M059K	DepMap CRISPR Gene Dependency	1.0	2.52831
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ACACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27565
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Rinm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.74162
squamous cell carcinoma	GWASdb SNP-Phenotype Associations	1.0	0.627528
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.880094
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LN443	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14739
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4535	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.657
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.37921
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal neurotransmitter level	MPO Gene-Phenotype Associations	1.0	null
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.974844
hsa-miR-4530	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
TSPAN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56498
Status epilepticus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
NUDT16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24594
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43137
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76846
primary auditory cortex (core)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.960113
Wolfram syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59431
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.568
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55658
XRCC5_02_114	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.58496
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298731
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.872
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62777
connective tissue disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.003387
substantia nigra compacta, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32265
Anterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38585
GHDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8236
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.442418
PMC11611169-pone.0314092.s001.docx-3-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93977
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04078
EGR1	ChEA Transcription Factor Targets	1.0	null
sensory perception of sound	GO Biological Process Annotations 2015	1.0	null
bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22603
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.069
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autosomal dominant nonsyndromic deafness 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35068
TUHR4TKB	CCLE Cell Line Gene Expression Profiles	-1.0	-1.6644
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83135
autoimmune disease of urogenital tract	GWASdb SNP-Disease Associations	1.0	1.27567
BEX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21174
Perturb_8418_KO_Yap1/Wwtr1_SRP143461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.51853
PMC12754461-ab-25-0268-Supplementary-3.pdf-21-SOX13_SOX13	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74579
Rce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormal kidney morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
INKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26083
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633549
EPB41L4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97741
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09994
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.675
TMEM126B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67292
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051066
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919544
Cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.699
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19044
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.205
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11158
ZNF230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94657
Cochlear labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
phosphate transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
TIRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6991
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5153
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-RA-A741-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899498
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.042557
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054729
Substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.917
Y-linked deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.55831
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23026
L-glutamate uniporter activity	GO Molecular Function Annotations 2023	1.0	null
Pendred Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.958
actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.928
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5742
peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142729
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11498
NPTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43121
CBX2	ENCODE Transcription Factor Targets	1.0	null
Neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.997
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.861482
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
PGAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7623
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
abnormal cochlear inner hair cell physiology	MPO Gene-Phenotype Associations	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF766	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43293
b65	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.856
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.890809
abnormal cochlear ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32548
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04497
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.826637
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991884
Cytoplasmic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.018
Heart Diseases	CTD Gene-Disease Associations	1.0	1.07305
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65923
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040918
KM12	CCLE Cell Line Gene CNV Profiles	1.0	1.55775
hsa-miR-629	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE220520_6_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HELLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6043
Autosomal dominant nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5434
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6228
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05295
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.638
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Granule cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.609
synaptic transmission, glutamatergic	GO Biological Process Annotations 2023	1.0	null
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.534
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.072
abnormal brain wave pattern	MPO Gene-Phenotype Associations	1.0	null
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.51086
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84172
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.750452
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09763
cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177217
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hepatic Encephalopathy	CTD Gene-Disease Associations	1.0	1.07947
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83848
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26835
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887422
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.4
ZNF726	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74721
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
Perturb_6136_KO_Nox2_SRP155219	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.8698
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27484
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3612
HIP1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80264
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584022
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24528
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00482
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14121
hsa-miR-512-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
ERAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47215
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24502
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-Netherlands-602-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.57406
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Synaptic Vesicle Pathway(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48168
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75154
CEBPZOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45379
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.656
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.093
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98051
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5325
hypertension	GWASdb SNP-Disease Associations	1.0	0.579107
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25955
RANGRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2551
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43605
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79568
Perturb_10858_KO_Sirt6_SRP190930	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.62016
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.36922
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914786
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.189
zonal layer of SC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03965
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5200-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
enlarged uterus	IMPC Knockout Mouse Phenotypes	1.0	null
hsa-miR-4448	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
abnormal uterus morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
MED11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47356
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.588
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95509
myopia	GWASdb SNP-Disease Associations	1.0	0.504986
ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
hsa-miR-4725-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MSRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16029
PG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.167
intermediate stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03958
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MIDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76037
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
hsa-miR-4428	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
EWSR1_02_122	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.16993
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27806
deafness, autosomal dominant 25	OMIM Gene-Disease Associations	1.0	null
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6474
HGC27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40771
abnormal nervous system electrophysiology	MPO Gene-Phenotype Associations	1.0	null
Transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.118
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.953292
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.667693
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.470711
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.892
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2198
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32544
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22663
enlarged lymph nodes	IMPC Knockout Mouse Phenotypes	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.59174
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378748
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55953
YY1AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11286
ZFP91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64534
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.562
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08765
hsa-miR-2277-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.255
CCDC74A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67881
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598871
Metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.319
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98446
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
medial part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82464
BE-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45109
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23922
Autosomal recessive nonsyndromic deafness 49	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91827
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.576816
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
IL6ST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89826
ventral midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262645
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19472
central gray substance of midbrain, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84865
Hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3489
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	1.74155
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
THUMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46398
Usher syndrome type 1G	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
TAFAZZIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93967
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.86898
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51726
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	2.42631
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74475
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.48192
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90632
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1792	DepMap CRISPR Gene Dependency	1.0	2.86599
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13524
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
ventral striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12941
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2359
neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459145
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47001
CDX2-21402776-INTESTINAL-VILLUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Temporal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
Rostral migratory stream	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
PABPC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26702
E2F4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31911
monoatomic ion transport	GO Biological Process Annotations 2025	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.38985
Central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.695
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051672
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828761
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.251366
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.97
sensory perception of mechanical stimulus	GO Biological Process Annotations 2015	1.0	null
SMIM10L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78086
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal trigeminal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
membrane potential driven uniporter activity	GO Molecular Function Annotations 2023	1.0	null
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cuticular plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.818
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.801
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.555274
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.741
RPE1SS51	DepMap CRISPR Gene Dependency	1.0	4.2333
Pain disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
NCIH1930	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02743
Meniere's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7141
Sympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.818
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
Medial habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1919
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
Nucleus preopticus medianus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.329
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.06148
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.19212
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5434
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.943735
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.011
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.784645
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16363
nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.648532
PMC11588066-pnas.2410331121.sapp.pdf-98-GTF2IRD1_GTF2IRD1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3144-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19437
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042487
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.992144
Arciform density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-3.00025
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03458
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12478
Nonsyndromic Hearing Loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0155
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Synaptic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70723
Pancreatitis	CTD Gene-Disease Associations	1.0	1.04352
Primary Biliary Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
Internal plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.456
cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266757
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60461
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.25698
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897252
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05894
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832538
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5905
SNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27103
C2CD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54406
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
RERE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1023
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-1272	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045804
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
astroglial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249329
FLOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29663
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82794
INBL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.618
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4358
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14099
Neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.127
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06664
JVM3	CCLE Cell Line Gene CNV Profiles	1.0	1.59192
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.594451
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80714
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.733
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055842
abnormal eye morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
primary biliary cirrhosis	GWASdb SNP-Disease Associations	1.0	1.27567
granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.553286
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Autosomal dominant nonsyndromic deafness 41	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
Autosomal recessive nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.545
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.9052
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.02239
TOMM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46765
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	0.199277
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10366
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36048
decreased prepulse inhibition	IMPC Knockout Mouse Phenotypes	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04058
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE62843,GSE64371_2_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03063
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.29
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.03827
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.729
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
abnormal adrenal gland morphology	MGI Mouse Phenotype Associations 2023	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.959302
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07465
abnormal cochlear hair cell physiology	MPO Gene-Phenotype Associations	1.0	null
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.02
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.898085
Lateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.837
B4GALT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51999
abnormal sensory neuron physiology	MPO Gene-Phenotype Associations	1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14492
gamma-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
Autosomal recessive nonsyndromic deafness 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.723
absent startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	2.16778
Seizures	CTD Gene-Disease Associations	1.0	1.32667
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04543
EML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57782
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31166
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 50	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.322
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44492
ZNF835	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37121
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11256
decreased cochlear inner hair cell number	MPO Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9516
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Neuron to neuron synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.194
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.5366
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050888
UFSP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35324
liver cirrhosis	GWASdb SNP-Disease Associations	1.0	1.27567
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837685
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.50001
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64816
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32377
SYT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49345
Vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.419
Axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.734
KDM4A	ENCODE Transcription Factor Targets	1.0	null
PTP4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59252
PMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9132
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6Y9-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07122
A-CA-04-2009(H1N1)_18Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.28354
STK11IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82033
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4644-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56821
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23207
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
KE97	CCLE Cell Line Gene CNV Profiles	1.0	1.46297
H3-3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95405
CPCN	CCLE Cell Line Gene Expression Profiles	1.0	1.78634
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35537
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ONECUT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76787
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Infralimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26457
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042057
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.469576
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
Perturb_4422_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.1961
hepatobiliary disease	GWASdb SNP-Disease Associations	1.0	0.30916
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.593
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97035
NLRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41186
Rectum adenocarcinoma_READ_TCGA-AG-3725-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Spinal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.918
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89422
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91771
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891637
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Auditory neuropathy spectrum disorder	ClinVar Gene-Phenotype Associations 2025	1.0	null
Dendritic tree	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.547
Glutamatergic neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
Nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1604
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.78126
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61321
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31503
NCIH526	CCLE Cell Line Gene Expression Profiles	1.0	2.61129
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17788
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03589
thymus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14254
NUP214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38092
GSE205021_3_v_1_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11108_KO_Cpt2/Ppara_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.9692
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49652
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82287
HCC1428	CCLE Cell Line Gene CNV Profiles	1.0	1.78625
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76239
Dorsal nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.17194
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891637
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04978
Synaptic vesicle cycle	KEGG Pathways 2026	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04458
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUS4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59294
deafness	GeneRIF Biological Term Annotations	1.0	null
TP63_01_200	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.56071
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8995
PAX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24687
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
C32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Malignant tumor of pancreas_saliva_GSE14245	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.34686
Pancreatic alpha cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.885
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835598
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16099_KO_Eed_SRP125082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.46117
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44694
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30703
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26763
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56948
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32171
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PRRX2_PRRX2	Rummagene Transcription Factor Associations 2026	1.0	null
excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.212627
abnormal organ of corti morphology	MPO Gene-Phenotype Associations	1.0	null
POU3F2-20337985-501MEL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DACH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17767
abnormal membranous labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
positive regulation of L-glutamate import across plasma membrane	GO Biological Process Annotations 2025	1.0	null
LRRFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61744
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62158
Nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
APBB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75134
medial part of the isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80471
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73358
Dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.767
CREB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58456
YY2_KD_GDS3788_490_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Glomus cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
DERL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0726
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978915
AFTPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10443
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.921118
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35043
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16172
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Respiratory system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
DNAAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69421
TMEM14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85943
PMC5746461__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.20255
GSE221577_4_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KPNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23655
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30023
biological_process	GO Biological Process Annotations 2015	1.0	null
integral component of synaptic vesicle membrane	SynGO Synaptic Gene Annotations	1.0	null
ZNF222	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36253
BEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00846
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7893
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16412
Nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.828
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65277
Lung adenocarcinoma_LUAD_TCGA-50-5944-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal synaptic acetylcholine release	MPO Gene-Phenotype Associations	1.0	null
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
nonsyndromic	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09829
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM210B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97157
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
absent cochlear nerve compound action potential	MGI Mouse Phenotype Associations 2023	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39988
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.866
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal startle reflex	MPO Gene-Phenotype Associations	1.0	null
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05593
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dementia	GWASdb SNP-Disease Associations	1.0	0.322316
regulation of acetylcholine uptake	GO Biological Process Annotations 2025	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052595
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SDF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81457
Fatty Liver	CTD Gene-Disease Associations	1.0	1.9469
Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09419
GCNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0135
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93882
WASF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.60941
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
hsa-miR-3122	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
abnormal cranial ganglia morphology	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.152
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB69	DepMap CRISPR Gene Dependency	1.0	3.67791
USB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13616
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17223
Prostate-hillock-club cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	1.62864
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.139915
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995508
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATP6V0A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07681
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.89007
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KMT2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60722
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44992
mantle zone of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80566
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.49991
TP63	ChEA Transcription Factor Targets	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46363
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46686
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.609
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84884
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04374
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.983906
Avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.364
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SLC transporter disorders	Reactome Pathways 2024	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.061367
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19437
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hearing impairment	HPO Gene-Disease Associations	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.866842
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Postsynaptic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.99
bone inflammation disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.052255
autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.67683
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormal innervation	MPO Gene-Phenotype Associations	1.0	null
Autosomal dominant nonsyndromic deafness 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
GPR108	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44459
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63233
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CENPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62546
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
l45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.295
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43681
GABARAPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93431
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.073655
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.733
DNAJC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.25803
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPHA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.614
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47608
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.861154
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.9366
Neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.505
Usher syndrome type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.068
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6551
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01411
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85516
Autosomal dominant nonsyndromic deafness 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.419
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30226
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.38128
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.956417
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
X-linked deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.32533
PMC7057110-MGG3-8-e1128-s001.docx-0-ALX3_ALX3	Rummagene Transcription Factor Associations 2026	1.0	null
dicarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
UNC13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96322
asymmetric, glutamatergic, excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
Erythromelalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
DIS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50492
RASSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48746
hsa-miR-1305	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
SRMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54682
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34115
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.39294
CSDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57874
abnormal sensory neuron innervation pattern	MPO Gene-Phenotype Associations	1.0	null
sodium:phosphate symporter activity	GO Molecular Function Annotations 2025	1.0	null
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0636
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05359
Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant nonsyndromic deafness 36	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.233
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.113
abnormal hair cell physiology	MPO Gene-Phenotype Associations	1.0	null
abnormal cochlear ganglion morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Autosomal dominant nonsyndromic deafness 25	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.461
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26491
SU8686	CCLE Cell Line Gene Expression Profiles	-1.0	-3.09727
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95441
abnormal ear morphology	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
abnormal cochlear hair cell number	MPO Gene-Phenotype Associations	1.0	null
Anterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
RCCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17455
SIVA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29925
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8283158-mmc2.xlsx-TCF4_NPC-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal recessive nonsyndromic deafness 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.551
Prostate-club cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	5.59532
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ADAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95907
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991104
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	2.95593
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01614
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4369
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81654
Synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.959
intermediate stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28193
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.628
ADRA2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34595
SP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850296
LUZP1-20508642-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.14392
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
neurological system process	GO Biological Process Annotations 2015	1.0	null
enhanced behavioral response to cocaine	MPO Gene-Phenotype Associations	1.0	null
PRKCSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78487
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
enhanced behavioral response to addictive substance	MPO Gene-Phenotype Associations	1.0	null
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38693
PMC5746461__F5	PFOCR Pathway Figure Associations 2024	1.0	null
EHBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71285
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23078
Perturb_11460_KO_Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.38895
Fourth ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2275
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12239
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.30028
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61897
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.788
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20683
GOLGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56514
abnormal neuron number	MPO Gene-Phenotype Associations	1.0	null
Postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.91
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75767
Medial dorsal nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
SALL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55568
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34529
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81105
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.117
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.641827
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09562
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6165
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.06002
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2024	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.06225
Cochlear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.573
hsa-miR-4803	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.050388
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16444
POLR2A	ENCODE Transcription Factor Targets	1.0	null
HT1197	DepMap CRISPR Gene Dependency	1.0	2.81304
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.747737
NGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63267
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
deafness	MPO Gene-Phenotype Associations	1.0	null
GSE62843,GSE64371_4_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of glutamate uptake involved in transmission of nerve impulse	GO Biological Process Annotations 2023	1.0	null
X-linked deafness 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
esophagus	GTEx Tissue Gene Expression Profiles	-1.0	-0.879717
IQGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88009
L-glutamate transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01378
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.048763
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37956
Marsili syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_3_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
decreased exploration in new environment	MGI Mouse Phenotype Associations 2023	1.0	null
mantle zone of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37353
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
TMEM145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.764
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00712
spinal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.617393
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22779
LIG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68769
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947254
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20412
hearing/vestibular/ear phenotype	MPO Gene-Phenotype Associations	1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82246
HUPT3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10906
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3908
Liver Diseases	CTD Gene-Disease Associations	1.0	1.7255
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_2_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.38701
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.28765
limited	GeneRIF Biological Term Annotations	1.0	null
SW1417	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56924
Perturb_11911_KD_Arntl2_SRP063609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19736
PMC6080909-JEM_20171312_TableS1.xlsx-miR-196_predicted-Table_S1_miR-196a_b_predicted_targets_by_PITA_PicTar_TargetScan_and_DIANA_prediction_algorithms_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4111
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.58754
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32185
oculomotor nucleus, Edinger-Westphal subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56854
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.062
Human - Motor Cortex - Cluster - SST+ KLHL1+ Layer 5-6 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7308
Presynaptic periactive zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
Cul4-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.354
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906566
Tic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.192
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP1R9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0142
Medial vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0136
identity	GeneRIF Biological Term Annotations	1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.883
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.388
decreased synaptic glutamate release	MPO Gene-Phenotype Associations	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.792854
NOS-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.676
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91633
l-glutamate transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16149
GSE133213_6_v_15_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.179847
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29183
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42314
Dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.723
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.56685
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.418
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47984
hsa-miR-4434	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.531
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45031
HSPB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07905
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.85764
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27404
Defective SLC17A8 causes autosomal dominant deafness 25 (DFNA25)	Reactome Pathways 2024	1.0	null
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13981
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
LAMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52748
acidic amino acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.792709
Laterodorsal tegmental nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.911
Autosomal dominant nonsyndromic hearing loss	ClinVar Gene-Phenotype Associations 2025	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34356
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.599
496100647_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2269
RERF-LC-MS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-299-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.86
medial parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01002
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UR-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inhibition	GeneRIF Biological Term Annotations	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10647
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.424
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17558
cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11223
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38121
Parahippocampal region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4555
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966169
Mouse - Motor Cortex - Cluster - Sncg+ Slc17a8+ GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5679
Dendritic tuft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.739614
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
HEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08017
HOXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02798
cell type cancer	GWASdb SNP-Disease Associations	1.0	0.287719
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.365
POU3F2	ChEA Transcription Factor Targets	1.0	null
abnormal startle reflex	IMPC Knockout Mouse Phenotypes	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7068
HES3_KO_GSE64449_186_mouse_Min6	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
hsa-miR-100-5p	MiRTarBase microRNA Targets	1.0	null
DGCR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.321
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55501
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40277
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
Hi-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
Nucleus preopticus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
Axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.115
abnormality of the liver	GWASdb SNP-Phenotype Associations	1.0	0.162066
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39511
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.666827
GSE173262_2_v_5_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_10769_KO_Jnk1_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.06243
CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-4753-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
MALL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25641
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55664
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04343
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78506
Epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.105
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.935
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5567
regulation of glutamate uptake involved in transmission of nerve impulse	GO Biological Process Annotations 2025	1.0	null
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828236
HNF4A	ChEA Transcription Factor Targets	1.0	null
Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3467	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.83432
HTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71697
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
hsa-miR-4489	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autosomal recessive nonsyndromic deafness 67	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
Sensorineural Hearing Loss, Bilateral	DisGeNET Gene-Disease Associations	1.0	null
SNU1272	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63716
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Carotid sinus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.349
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.0958
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.481
TIGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01599
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DNAJC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89372
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79693
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36193
decreased cochlear inner hair cell number	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04497
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16858
Lateral habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.371
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31849
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06278
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.1513
496100305_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15491
excitatory synapse	GO Cellular Component Annotations 2025	1.0	null
Leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.12569
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1053
Nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.065
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11056_KD_Eif4ebp3_SRP251186	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53795
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38681
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02048
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9421
PRMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05195
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11888
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GSE165682_4_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.12807
chloride channel activity	GO Molecular Function Annotations 2025	1.0	null
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.23
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949877
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.3671
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.15979
Medial geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
MDA-MB-361	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.59497
phosphate ion transport	GO Biological Process Annotations 2023	1.0	null
GSE159967_3_v_0_arid5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.582
SHROOM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86217
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.165492
superficial stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1041
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053751
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3756
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.399
ZHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04641
CORL47	CCLE Cell Line Gene Expression Profiles	1.0	1.46252
RRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13684
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.703536
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
neurotransmitter transport	GO Biological Process Annotations 2025	1.0	null
ZC3H15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31022
GSE139992_1_v_0_mboat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99515
DDX60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98238
Stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.34
caudate putamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329727
arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.052255
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.868
CLASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81809
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06112
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.917
hsa-miR-186	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
Medial cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
Labyrinthine zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051397
PMC12176927-125_2025_6424_MOESM1_ESM.pdf-23-FOXG1_FOXG1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal cochlear ihc efferent innervation pattern	MPO Gene-Phenotype Associations	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
Middle ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.758
mantle zone of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20527
abnormality of the integument	GWASdb SNP-Phenotype Associations	1.0	0.087926
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096451
amide transport	GO Biological Process Annotations 2023	1.0	null
ENPP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26821
PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Genes_bound_by_KLF10_in_their_-10_1kb_region_or_differentially_expressed_in_WT_vs_HepKO_hepatocytes_challenged_with_high_sugar_KLF10	Rummagene Transcription Factor Associations 2026	1.0	null
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1679
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873528
ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.859392
synapse part	GO Cellular Component Annotations 2015	1.0	null
Brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.678
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1698_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.34075
Infertility, Male	CTD Gene-Disease Associations	1.0	1.01512
WNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26365
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7535
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18581
BCLAF1_01_214	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.8103
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61272
synaptic transmission, glutamatergic	GO Biological Process Annotations 2025	1.0	null
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094214
Perturb_8947_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
RALDH2_KO_GSE43578_6_mouse_head (rostral or posterior)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.09541
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08813
FUT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74353
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Saccule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25113
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3489
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33915
COX6B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92905
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.39972
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.863167
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
FAM117A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42889
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16481
monoatomic anion channel activity	GO Molecular Function Annotations 2023	1.0	null
abnormal auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5514
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.733
Aortic body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11252_KO_Med13_SRP302233	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.15268
regulation of amine transport	GO Biological Process Annotations 2025	1.0	null
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79202
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58705
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11387
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12395
PL4	DepMap CRISPR Gene Dependency	1.0	4.95631
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
SFXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99654
SOX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5078
abnormal startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898331
Cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.664
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80395
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
Pars compacta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.684
dopaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289939
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
Excitatory synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04989
organic acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2991
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23167
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.355
Lateral vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
GSE131649_6_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Smooth endoplasmic reticulum cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.579
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857085
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1384
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29865
GSE126127_2_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224311_3_v_2_chaetocin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100217_1_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3943
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4882
NABP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51428
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063742
midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.608124
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08811
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1703
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.508
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DOTC2-4510	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal dominant Emery-Dreifuss muscular dystrophy 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
amino acid transport	GO Biological Process Annotations 2015	1.0	null
Proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.097
system process	GO Biological Process Annotations 2015	1.0	null
xenopus a6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388158
isthmic basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45659
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.441
NKX2-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14555
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
L-glutamate import	GO Biological Process Annotations 2025	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07382
possible	GeneRIF Biological Term Annotations	1.0	null
L-glutamate import	GO Biological Process Annotations 2023	1.0	null
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.801
vascular disease	GWASdb SNP-Disease Associations	1.0	0.069778
Human - Motor Cortex - Cluster - PAX6+ FREM2+ Layer 2 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
Ventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29698
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
impaired behavioral response to xenobiotic	MGI Mouse Phenotype Associations 2023	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.12886
Perturb_10732_KO_Depdc5_SRP311760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.21167
GSE212486,GSE212488_2_v_3_gata4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171292_6_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970891
Medial entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
hsa-miR-378g	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19843
HSPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8463
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86967
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10075
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26754
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98658
Epilepsy	HuGE Navigator Gene-Phenotype Associations	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
IZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994171
abnormal ear physiology	MPO Gene-Phenotype Associations	1.0	null
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
Heart	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HSDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34264
non-neuronal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.466
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89817
LS411N	DepMap CRISPR Gene Dependency	1.0	9.19551
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51274
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4047
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16664
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
decreased sensory neuron number	MPO Gene-Phenotype Associations	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.965772
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07639
GSE169713,GSE169715_1_v_2_tert_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65104
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.74
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.991
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45157
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.003
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93397
Narcolepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.19
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
nonsyndromic deafness	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE129389_0_v_3_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DNA recombinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.512
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13026
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
ZNF469	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41247
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89782
Central amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7545
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.445
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11135
excitatory synapse	GO Cellular Component Annotations 2023	1.0	null
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF7IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81306
monoatomic anion channel activity	GO Molecular Function Annotations 2025	1.0	null
NG2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0805
Neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.797
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46123
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15709
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85667
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal recessive nonsyndromic deafness 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29917
Sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.25427
Developmental and epileptic encephalopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
PTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31049
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839396
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11481
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17535
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.356
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09423
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased neuron number	MPO Gene-Phenotype Associations	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
sodium-dependent phosphate transport	GO Biological Process Annotations 2025	1.0	null
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77162
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869868
SU8686	DepMap CRISPR Gene Dependency	1.0	4.42554
GSE178227_1_v_2_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20619
NCI-H2227	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
C13orf42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42391
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.521
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56392
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14476
Perturb_4457_OE_Atg7_SRP310882	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.77696
L3MBTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7246
l-glutamate transmembrane transport	GO Biological Process Annotations 2015	1.0	null
l-glutamate transport	GO Biological Process Annotations 2015	1.0	null
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75291
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71548
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
hsa-miR-670	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25457
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.829495
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62564
abnormality of the abdominal organs	GWASdb SNP-Phenotype Associations	1.0	0.082585
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78658
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
neuron projection	GO Cellular Component Annotations 2015	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.63504
L-glutamate transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
abnormal synaptic acetylcholine release	MGI Mouse Phenotype Associations 2023	1.0	null
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.332
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
hyperactivity	MPO Gene-Phenotype Associations	1.0	null
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
absent startle reflex	MPO Gene-Phenotype Associations	1.0	null
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61758
deafness	MGI Mouse Phenotype Associations 2023	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36593
aminoglycoside-induced deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
Mesocorticolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.792854
USH2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
Brain_CT2_Inh L5-6 SST KLHL1	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.705583
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68082
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.72202
ASH3	DepMap CRISPR Gene Dependency	1.0	3.28407
synaptic vesicle neurotransmitter loading	SynGO Synaptic Gene Annotations	1.0	null
HNRNPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14907
attention deficit hyperactivity disorder	GWASdb SNP-Disease Associations	1.0	0.970747
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69015
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
AMIGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08253
HNRNPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16852
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PAS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.615
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864637
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97427
neuron part	GO Cellular Component Annotations 2015	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968055
TSPAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21391
developmental	GAD High Level Gene-Disease Associations	1.0	0.293278
disease	GWASdb SNP-Disease Associations	1.0	0.051113
SMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98382
neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.923339
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.947808
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.435651
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.93632
artery disease	GWASdb SNP-Disease Associations	1.0	0.097871
hsa-miR-656	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05337
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
dicarboxylic acid transport	GO Biological Process Annotations 2023	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2294
Trichinellosis	DisGeNET Gene-Disease Associations	1.0	null
MAST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4084
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.55398
Perturb_11197_KD_Pten_SRP311091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.027
PCBP1_02_115	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
Habenular trigone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.29
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
Sbac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2558
central retinal artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09209
Perturb_11103_KO_Depdc5_SRP219943	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.72479
abnormal inner hair cell synaptic ribbon morphology	MPO Gene-Phenotype Associations	1.0	null
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11056
RNF185	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85169
abnormality of refraction	GWASdb SNP-Phenotype Associations	1.0	0.346711
hsa-miR-3128	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28798
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41512
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.70793
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1057
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33457
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78852
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79568
RNF2	ENCODE Transcription Factor Targets	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37134
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24336
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4977
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7595
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.106481
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
synaptic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2522
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
Neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.344
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WW-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF783	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46874
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.983
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.586
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.861
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
increased or absent threshold for auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.811
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYDGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01638
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.55476
OCUBM	DepMap CRISPR Gene Dependency	1.0	4.16562
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
L-amino acid transport	GO Biological Process Annotations 2025	1.0	null
Cocaine	CTD Gene-Chemical Interactions	1.0	null
hsa-miR-4775	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Organic anion transporters	Reactome Pathways 2024	1.0	null
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_11257_KO_Pparg_SRP294559	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.8668
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.864605
Hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.411
GATA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54697
enlarged uterus	MGI Mouse Phenotype Associations 2023	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.334
Xc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58242
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.74433
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.944
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9676
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32548
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE126127_2_v_3_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuroactive ligand signaling	KEGG Pathways 2026	1.0	null
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68862
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29728
hsa-miR-922	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
sensorineural hearing impairment	MPO Gene-Phenotype Associations	1.0	null
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7468
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.155
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0617
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29124
Arteriosclerosis	CTD Gene-Disease Associations	1.0	1.03159
mesomere 2 (preisthmus or caudal midbrain)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06804
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
cSARS Bat SRBD_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73991
hsa-miR-3913-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19761
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02603
Rh-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11055
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.40541
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26247
increased locomotor activity	MGI Mouse Phenotype Associations 2023	1.0	null
Trichinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
MEIOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52313
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.24267
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.24689
PMC7378272-mmc3.docx-0-SIX1_SIX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96038
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1148
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.842
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.12863
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.98446
Perturb_11183_KO_Pcgf6_SRP238553	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.79346
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953751
epithelial-stromal TGFBI dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.16801
carcinoma	GWASdb SNP-Disease Associations	1.0	0.727991
Stereocilia tip-link density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55929
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.148
l-amino acid transport	GO Biological Process Annotations 2015	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.831365
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NONO_02_93	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.85798
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.97366
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
ABL1_druginhibition_77_GSE24493	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.537
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17441
SKN3	DepMap CRISPR Gene Dependency	1.0	3.44131
ZDHHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62961
hsa-miR-766	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49656
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.901
retinal vascular occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.596402
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11481
TAF5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03037
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.172201
hsa-miR-302f	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.467
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75568
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.881016
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1712
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.95424
cytoplasmic vesicle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76752
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19971
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
Midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.523
EZH2	ENCODE Transcription Factor Targets	1.0	null
trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358174
JPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
Dorsal claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15311
laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454512
GSE237040_0_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7595
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.672
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56138
PCBP2_02_123	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.70044
Nape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
CBX8	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21573
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37979
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46243
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51731
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03594
nucleus of Darkschewitsch, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.18783
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85186
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83431
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.149
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0775
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32488
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
Dopaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.937
TP53I13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56761
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79261
Corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.392
Poisoning	CTD Gene-Disease Associations	1.0	1.08584
positive regulation of amino acid uptake involved in synaptic transmission	GO Biological Process Annotations 2023	1.0	null
TUSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53095
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.95195
Ionotropic glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.361
Hereditary spherocytosis type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38189
Autosomal dominant nonsyndromic deafness 3B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
Pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.441
UACC257	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35775
hsa-miR-3163	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.026
Peripheral vertigo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
squamous cell carcinoma	GWASdb SNP-Disease Associations	1.0	0.727991
TMEM223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58894
L-glutamate uniporter activity	GO Molecular Function Annotations 2025	1.0	null
PABPC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.64871
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914786
PMC5859169__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Cerebellar Purkinje cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.551
GOLPH3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.523982
Gilles de la Tourette syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852358
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4965
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5893
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SRRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68092
Autonomic nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29135
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892014
hsa-miR-4298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37231
tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428783
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75724
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44467
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23411
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08088
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876808
putamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03758
KNDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67776
Pericellular basket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.92
L-glutamate transmembrane transport	GO Biological Process Annotations 2025	1.0	null
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.00103
solute:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.638
abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.108504
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.411657
GSE190316,GSE190324_6_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
Meynert's basal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
TMEM219	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64757
colon	GTEx Tissue Gene Expression Profiles	1.0	1.0566
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
TE-03 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79568
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.59961
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
neurotransmitter loading into synaptic vesicle	GO Biological Process Annotations 2023	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8926
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.03237
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84708
abnormal biliary tract morphology	GWASdb SNP-Phenotype Associations	1.0	0.388001
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4783
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.19672
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991104
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32853
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.753
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.15495
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1451
immunoreactivity	GeneRIF Biological Term Annotations	1.0	null
L-alpha-amino acid transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.978
Autosomal dominant nonsyndromic deafness 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.736
tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.481259
transporter	GeneRIF Biological Term Annotations	1.0	null
ZNF22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49918
Haloperidol	CTD Gene-Chemical Interactions	1.0	null
Sensorimotor area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
HIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51433
U2AF2_02_105	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.0
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3053
Occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.7
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65514
abnormal cochlear inner hair cell number	MPO Gene-Phenotype Associations	1.0	null
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53395
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21164
Autosomal recessive nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Nucleus accumbens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0182
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59759
SLC25A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56868
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.02736
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	1.61092
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
b12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PACS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40676
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15455
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44085
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.96
EOMES_OE_GDS5077_65_human_RUES2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.361
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.910946
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.906587
KLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16502
Rhomboid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.612
ZMYM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51619
GRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38484
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75522
OCT4-21477851-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.999344
Neoplasms	CTD Gene-Disease Associations	1.0	1.03197
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26314
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.02188
Rabies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.875
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.80258
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51586
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.39559
SPTBN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08884
Sarcoma_SARC_TCGA-HB-A3YV-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954683
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32131
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40971
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08634
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06835
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.74525
parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.179802
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04512
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.446
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07275
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942162
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.56
GABA-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.181
hsa-miR-31	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
Lung adenocarcinoma_LUAD_TCGA-97-7546-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09994
GCIY	CCLE Cell Line Gene Expression Profiles	1.0	2.25277
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.925
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.38863
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98031
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
X-linked epilepsy with variable learning disabilities and behavior disorders	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
myopia	GWASdb SNP-Phenotype Associations	1.0	0.431365
PMC10282096-41467_2023_39038_MOESM4_ESM.xlsx-All_genes_Upregulated-ENSG00000177426_TGIF1	Rummagene Transcription Factor Associations 2026	1.0	null
IVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30347
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ACY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54119
Adrenocortical carcinoma_ACC_TCGA-OR-A5JF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14922
lateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09264
r1 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34315
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01856
symporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA2-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Dentate gyrus mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.701
GSE207914_2_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal somatic nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
dicarboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
GER cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.607
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.740064
brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218398
membrane	GO Cellular Component Annotations 2015	1.0	null
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
anterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31072
brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.231795
medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0037
Ionotropic glutamate receptor pathway	PANTHER Pathways	1.0	null
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80233
Tectum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.396
LIPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0767
Generalized anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
ATPase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065072
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68974
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.08938
erg_19359602_huvec_lof_human_gpl570_gds3557	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.061354
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
Frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.504
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.51562
Purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.088
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m2 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49386
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MLXIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41687
Weight Gain	CTD Gene-Disease Associations	1.0	1.05423
chloride transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.544549
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.066443
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82639
Disease	Reactome Pathways 2024	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03783
Liver Failure	CTD Gene-Disease Associations	1.0	1.25494
MAGED4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00234
BMI1-19503595-MEFC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.5337
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Sternocleidomastoid muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33869
PLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80943
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.092077
NBDY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31018
ZNHIT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0858
PPP1R3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8314
cloned	GeneRIF Biological Term Annotations	1.0	null
NDUFV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85668
Autosomal recessive nonsyndromic deafness 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Trigeminal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.572
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54551
SLC2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35589
Transient Ischemic Attack	DisGeNET Gene-Disease Associations	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73925
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
RBM34_02_121	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.45943
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.434
SH3GLB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84577
KLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.16264
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16287
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_12Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.95302
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44314
sensorineural hearing loss	MPO Gene-Phenotype Associations	1.0	null
Perturb_16106_KO_Bap1_SRP360900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
MONOMAC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9599
periventricular stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02379
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9380317-13045_2022_1327_MOESM3_ESM.xlsx-Table_S7-Table_S7_Top_500_differentially_modified_gene_bodies_between_MM_and_its_precursors_in_AA_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.01512
IGFBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6322
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.389
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SAC3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55826
Hyperekplexia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26293
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01081
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.50248
CSPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Internal capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
GSE149075_3_v_11_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Dentate gyrus HICAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.474646
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.388
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870843
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50766
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE227592_6_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80002
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26186
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57088
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36631
bone	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.857839
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.54561
PMC3470785-NIHMS377161-supplement-3.pdf-166-ZNF212_ZNF212	Rummagene Transcription Factor Associations 2026	1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.379875
Variable Expressivity	DisGeNET Gene-Phenotype Associations	1.0	null
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23241
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7385
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.24581
Motor trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
Mr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058483
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
FANCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67412
Arachnoid mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32772
Nonsyndromic Deafness	DisGeNET Gene-Disease Associations	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3324-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99126
GNPNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14977
heart	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PIGO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88012
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07312
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.542
Glutamate decarboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.907
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0662
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5434
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09994
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00168
Retrosplenial area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08782
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44405
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
migraine	GWASdb SNP-Disease Associations	1.0	0.793562
Caudate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28878
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7462
L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
ADAM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68283
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04514
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925313
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.987
hsa-miR-1253	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68F-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5109-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169334,GSE169336_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
SLC2A12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00684
overlaps	GeneRIF Biological Term Annotations	1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2306
cochlear ganglion degeneration	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87224
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859822
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898331
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257907
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.749427
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31342
LHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29919
nonconvulsive seizures	MPO Gene-Phenotype Associations	1.0	null
DDX3Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62084
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
regulation of amine transport	GO Biological Process Annotations 2023	1.0	null
hsa-miR-4516	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE129389_0_v_1_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052788
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.041276
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4655
PAQR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31784
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41882
Adrenocortical carcinoma_ACC_TCGA-OR-A5J3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.67337
neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.58322
DCAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56477
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05722
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
trichinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.939534
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
CAS1	DepMap CRISPR Gene Dependency	1.0	2.04512
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03288
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68617
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
NCIH196	CCLE Cell Line Gene CNV Profiles	1.0	2.4395
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.10562
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67853
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01572
inner CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09367
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.695148
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.47231
GSE158815_5_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.19146
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.88782
Lateral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
Sexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.205
cataract	IMPC Knockout Mouse Phenotypes	1.0	null
Y-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
HBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34311
Autosomal recessive nonsyndromic deafness 23	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11211180-405_2024_8492_MOESM1_ESM.pdf-2-POU4F3_POU4F3	Rummagene Transcription Factor Associations 2026	1.0	null
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06477
Lateral wall of outer hair cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
organic acid transport	GO Biological Process Annotations 2015	1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
RHNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33069
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Dura mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
TRAPPC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42318
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Infundibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7774
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33292
Agranular insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
Pulvinar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871927
Dentate granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.198
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59657
Apolipoprotein C-III deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
abnormal behavioral response to cocaine	MPO Gene-Phenotype Associations	1.0	null
GSE180525,GSE180528_2_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80767
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
Basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.5
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.342
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43507
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
trochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.67375
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP1_01_208	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61785
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.059812
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46686
Neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.826
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053333
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.97691
Dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
abnormal hearing physiology	MPO Gene-Phenotype Associations	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.980135
SMZ1	DepMap CRISPR Gene Dependency	1.0	2.06871
inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.1253
SLC35A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49488
organic anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43204
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
abnormal nervous system morphology	MPO Gene-Phenotype Associations	1.0	null
olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247079
Auditory capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.849
SP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29765
NCI-H2444	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BBS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79642
hsa-miR-4502	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
Hepatitis	CTD Gene-Disease Associations	1.0	1.61413
increased or absent threshold for auditory brainstem response	MPO Gene-Phenotype Associations	1.0	null
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
Paroxysmal extreme pain disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
medial vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.433374
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
Neurotransmitter receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.375
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
Autosomal recessive nonsyndromic deafness 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06443
Lm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94222
single-organism process	GO Biological Process Annotations 2015	1.0	null
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78593
Autosomal dominant nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.9
cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.54217
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ARG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7088
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.381
GALE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50989
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
REDD1_Repression_GDS3558_73_human_Blood Myeloid Cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42944
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32159
Autosomal dominant nonsyndromic deafness 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.741091
ZFP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50094
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2461	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sciatic Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14238
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46042
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.051008
Pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
P2RX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01295
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06476
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64251
m1 (rostral) midbrain tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32756
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88433
vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.414293
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905759
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80612
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32597
STAMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16019
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypothermia	CTD Gene-Disease Associations	1.0	1.12973
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338545
cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.162001
thorax	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Charcot-Marie-Tooth disease X-linked recessive 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.02522
Exocytic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Glutamatergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.376
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23215
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.028
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15442
hsa-miR-3926	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
hsa-miR-4427	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
hsa-miR-4639-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
nonconvulsive seizures	MGI Mouse Phenotype Associations 2023	1.0	null
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16201
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19892
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.80019
Major facilitator superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.823
positive regulation of L-glutamate import across plasma membrane	GO Biological Process Annotations 2023	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
pars compacta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.566428
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02647
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
abnormal cochlear hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.30381
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7414
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perilymphatic space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.455
KLHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13088
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53987
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897252
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.945329
solute:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10181
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.377
RRM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8246
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06461
Linear Atrophy	DisGeNET Gene-Disease Associations	1.0	null
Sensory Perception	Reactome Pathways 2024	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37433
NR1I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37049
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.889
Globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.054
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.53814
Exine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
CTCFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7947
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3152
decreased neurotransmitter release	MPO Gene-Phenotype Associations	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051494
Otosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23205
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
HS172T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49617
SLVL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.472
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20605
intermediate stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18395
MIER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35569
C14orf93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86564
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.585
transporter activity	GO Molecular Function Annotations 2015	1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32024
positive regulation of glutamate uptake involved in transmission of nerve impulse	GO Biological Process Annotations 2025	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.08904
hsa-miR-150	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
IM95	DepMap CRISPR Gene Dependency	1.0	3.36888
MAJIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71959
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4567
small	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.512
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40244
Perturb_10917_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.14341
all	GWASdb SNP-Phenotype Associations	1.0	0.043977
acute lymphoblastic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074073
sodium-dependent phosphate transport	GO Biological Process Annotations 2023	1.0	null
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98643
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.653807
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.678
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02369
deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4576
hsa-miR-578	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Thorny excrescence	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
SCABER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48497
eye disease	GWASdb SNP-Disease Associations	1.0	0.092077
liver disease	GWASdb SNP-Disease Associations	1.0	0.408005
PITX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48136
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2202
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.073852
abnormal eye morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6776
SYVN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98884
Cocaine abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165939_2_v_1_poldip2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FKBP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65219
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.33966
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.514
Weight Loss	CTD Gene-Disease Associations	1.0	1.78378
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
inner	GeneRIF Biological Term Annotations	1.0	null
Lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
drug-induced hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.311377
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02677
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.449
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
Lung cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16848
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COL4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48606
YD38	DepMap CRISPR Gene Dependency	1.0	3.56735
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.037
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
dentate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387404
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36947
BCCIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90296
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65286
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15984
Autosomal recessive nonsyndromic deafness 79	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.97622
ZNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18543
SNU1066	CCLE Cell Line Gene Expression Profiles	1.0	1.8974
SETD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75208
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.47808
Perturb_4417_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NCI-H2141	COSMIC Cell Line Gene Mutation Profiles	1.0	null
enlarged lymph nodes	MGI Mouse Phenotype Associations 2023	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.338
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.796
abnormal sensory neuron morphology	MPO Gene-Phenotype Associations	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	0.500605
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.367
MAP4K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40374
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
neurotransmitter loading into synaptic vesicle	GO Biological Process Annotations 2025	1.0	null
Catalepsy	DisGeNET Gene-Disease Associations	1.0	null
MAPK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63748
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6551
medial basal reticular formation of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01487
Hypertrophy	CTD Gene-Disease Associations	1.0	1.04501
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.417337
PUM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46478
basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.528719
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82721
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987724
GATA2_01_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.58496
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.122
Optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.824
mantle zone of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82464
H2369	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.118168
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7501
ZFHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89328
bone disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.052255
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.333
SLC6A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06378
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905759
all	HPO Gene-Disease Associations	1.0	null
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09606
CDY2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89653
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27881
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29579
TOMM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7393
b9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
PMC10185556-41467_2023_38439_MOESM3_ESM.xlsx-ST19_MR_results-nearest_gene_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
APOBEC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22835
SNU1077	CCLE Cell Line Gene Expression Profiles	-1.0	-2.44284
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11787
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.787
cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169826
preisthmic tegmentum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49386
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 13	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
HS606T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62752
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.778155
GSE171292_1_v_0_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.4926
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76573
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
abnormal cochlear sensory epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
Asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.16
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7075
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06007
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53743
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72338
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M8-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-MES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25121
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056333
SNU81	DepMap CRISPR Gene Dependency	1.0	7.22703
CCDC9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95649
GSE212486,GSE212488_0_v_1_gata4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diagonal band	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.043
Perturb_9788_KO_Hif1a_ERP133576	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.55856
Autosomal recessive nonsyndromic deafness 103	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.347
Regio oralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09264
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11529
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13188
immune system disease	GWASdb SNP-Disease Associations	1.0	0.078681
SPOTS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
RBM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60138
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68317
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77051
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04497
SPTBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20678
Postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.936
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01713
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18984
Peripheral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.921
medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.637999
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.546
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
Varicosity	DisGeNET Gene-Disease Associations	1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
SW756	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_10719_KO_Nrf2_SRP336215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.34642
TE-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39085
CREB1_01_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.94801
Presynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
SRPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90611
abnormal neurotransmitter uptake	MGI Mouse Phenotype Associations 2023	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06729
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3337
GATA2_01_193	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59495
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97193
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81229
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.736
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052937
RABEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98313
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.434
Thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.048
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36446
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.05236
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.626677
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.987209
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.51744
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.70363
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
Posterior periventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27818
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.654686
Cornu ammonis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal action potential	MPO Gene-Phenotype Associations	1.0	null
Cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.382
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.927
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87073
UHO1	DepMap CRISPR Gene Dependency	1.0	2.93485
Rubrospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03833
dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.349105
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246567_0_v_1_acat2_human	RummaGEO Gene Perturbation Signatures	1.0	null
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45185
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10976
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24119
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90008
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950978
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.105
HPAFII	DepMap CRISPR Gene Dependency	1.0	7.37317
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03809
Acoustic neuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
Amniotic cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827359
KIF5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.046
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.06808
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4929
Multimeric ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
L-alpha-amino acid transmembrane transport	GO Biological Process Annotations 2023	1.0	null
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5463
Erythrokeratodermia variabilis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23688
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848895
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.84109
CUX1-19635798-MULTIPLE-CANCER-TYPES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920241
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.70595
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.610943
Nucleus reuniens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23723
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.1845
Limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.676
ANP32E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4171
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936742
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47685
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9759
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59539
Lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.087
TAL1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Caudate putamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.706
MKNK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89495
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44711
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.872917
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
decreased startle reflex	MGI Mouse Phenotype Associations 2023	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.492157
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6676
abnormal neurotransmitter secretion	MPO Gene-Phenotype Associations	1.0	null
VPS13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53843
TBP	ENCODE Transcription Factor Targets	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.01587
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Proteinuria	CTD Gene-Disease Associations	1.0	1.11911
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.356
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.681064
Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intralaminar nuclei of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02635
Major facilitator superfamily domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25366
Subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.698
Dendritic branch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.401
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.553
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920552
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045977
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3169
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34777
SEZ6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
Intracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.379
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.052255
headache	GWASdb SNP-Phenotype Associations	1.0	0.306028
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21924
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26665
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.035
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.546
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891637
Thymus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Intrinsic component of synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
mantle zone of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24622
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.304
Rheaume et al.Nat Commun.32_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50917
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1185
sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.18281
Prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.116
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991104
lymphoid tissue	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_10709_KO_Ezh1/Ezh2_SRP133172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Edema	CTD Gene-Disease Associations	1.0	1.37789
Medial amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
LAMB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35801
substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.734735
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.171
D502MG	DepMap CRISPR Gene Dependency	1.0	2.20547
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.672
DMRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33236
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55702
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.3543
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54858
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25168
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.201
Neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.915
mantle zone of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22859
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04125
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37548
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
Sensory processing of sound	Reactome Pathways 2024	1.0	null
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.65753
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.186
Perturb_11459_KO_Ezh2/Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.2218
ZDHHC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68156
globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.644074
Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	2.44503
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00118
subiculum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.827578
Deafness, Autosomal Dominant 25	CTD Gene-Disease Associations	1.0	2.88009
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90492
retinal artery occlusion	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.977585
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.653
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
localization	GO Biological Process Annotations 2015	1.0	null
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18722
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
Hypotension	CTD Gene-Disease Associations	1.0	1.02821
Sudden infant death syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.966812
Autosomal dominant nonsyndromic deafness 64	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15628
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6906-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LAMTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82828
Deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.914
Shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.289
IDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88101
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.36161
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12411
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10297
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
sodium:phosphate symporter activity	GO Molecular Function Annotations 2023	1.0	null
TSSK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16493
NDUFA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18045
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.166
LDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57969
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC9558712-Data_Sheet_2.xlsx-POU3F4_p_C327X_vs_CTRL-gene_name_POU3F4	Rummagene Transcription Factor Associations 2026	1.0	null
Cone telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.813
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.37453
Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Common_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
abnormal lymph node morphology	IMPC Knockout Mouse Phenotypes	1.0	null
GSE248858_5_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0856
Acetylcholine	CTD Gene-Chemical Interactions	1.0	null
anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.543756
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79493
Autosomal recessive nonsyndromic deafness 28	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
ROR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59397
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE169155_3_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP2R5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32861
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70P-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37931
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
enhanced behavioral response to xenobiotic	MPO Gene-Phenotype Associations	1.0	null
Midbrain, behavioral state related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65319
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
m1B part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66279
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58889
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.849354
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28995
Hypoglossal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
abnormal eye physiology	GWASdb SNP-Phenotype Associations	1.0	0.177114
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.710579
post-traumatic stress disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
biliary tract abnormality	GWASdb SNP-Phenotype Associations	1.0	0.354639
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_RFX-Unnamed_1_RFX1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
decreased startle reflex	IMPC Knockout Mouse Phenotypes	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41704
F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14268
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42101
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91342
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11391
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21093
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.513677
axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.47844
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49434
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8177
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
GNRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79704
SW626	DepMap CRISPR Gene Dependency	1.0	3.2413
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13783
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.069
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.9034
docking	GeneRIF Biological Term Annotations	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7473
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.489
Hyperplasia	CTD Gene-Disease Associations	1.0	1.58421
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.937699
Perturb_11094_KO_Regnase1_DRP004811	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.5519
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44207
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867477
acidic amino acid transport	GO Biological Process Annotations 2023	1.0	null
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90457
CUX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68696
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19978
exocytic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.191
Photoreceptor inner segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.791877
CDS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40205
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83846
SOX9_01_308	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60266
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.357
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20842
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65462
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23219
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.301
Tenia tecta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44215
Diabetes Mellitus, Type 2	CTD Gene-Disease Associations	1.0	1.05423
Neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.722
Lung carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
Usher syndrome type 1C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.2
intermediate part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24688
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0867
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.24074
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
Autosomal dominant nonsyndromic deafness 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Ensembl_ID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Presynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.98
Amino acid and oligopeptide SLC transporters	Reactome Pathways 2014	1.0	null
shows	GeneRIF Biological Term Annotations	1.0	null
Laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.46
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72195
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.154
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.792
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.352
ventral tegmental area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.845842
astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255234
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5353
GSE171292_5_v_2_ehhadh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.8408
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10601
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.867477
RCC-ER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
granule cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.391553
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18653
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.13675
GSE125007,GSE125008_5_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31214
DAGLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70395
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33635
COLO-741	COSMIC Cell Line Gene Mutation Profiles	1.0	null
synaptic vesicle cycle	GO Biological Process Annotations 2025	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.970747
Deafness	DisGeNET Gene-Disease Associations	1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11568
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00374
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VCPKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84921
NCI-H660	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.20143
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.46727
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67098
Adrenocortical carcinoma_ACC_TCGA-OR-A5LJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09207
Usher syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.765
Disorders of transmembrane transporters	Reactome Pathways 2024	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1055
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
H2810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841287
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.919413
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28497
FGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54187
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11768
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.05089
CARD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16943
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9328
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31202
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.7782
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.284
Perineuronal net	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
Retrograde endocannabinoid signaling	KEGG Pathways 2026	1.0	null
Choroideremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11005
Periventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01453
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
GSE148692,GSE148695_5_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C2orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87266
clathrin-coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55824
Leber congenital amaurosis 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
Sensory processing of sound by inner hair cells of the cochlea	Reactome Pathways 2024	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51401
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01709
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95118
gastrointestinal system disease	GWASdb SNP-Disease Associations	1.0	0.120469
tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769027
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78441
abnormal sensory ganglion morphology	MPO Gene-Phenotype Associations	1.0	null
acidic amino acid transport	GO Biological Process Annotations 2025	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.771
only	GeneRIF Biological Term Annotations	1.0	null
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28366
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
Ma-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051274
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.855091
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1345
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19782
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15083_KD_Nsd1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6668
Perturb_8948_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.699
cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.859258
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02295
USP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74735
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61697
GSE125219,GSE125221_4_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cannabis abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825595
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29755
DSCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76809
Autosomal dominant nonsyndromic deafness 9	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.975
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955824
Autosomal recessive nonsyndromic deafness 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Nucleolar ribonuclease P complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.98
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79568
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.186
Somatodendritic compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.577
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.901
Human - Motor Cortex - Cross-Species Cluster - Sncg+ GABAergic neuron_2	HuBMAP Azimuth Cell Type Annotations	1.0	null
ZFP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23283
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991884
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850445
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00252
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.539793
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057304
Inferior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
CLSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41164
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.934008
abnormal kidney morphology	IMPC Knockout Mouse Phenotypes	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.3699
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16394
Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
Deafness, autosomal dominant 25	ClinVar Gene-Phenotype Associations	1.0	null
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
Coma	CTD Gene-Disease Associations	1.0	1.25745
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48323
Ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.077
NCLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22194
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7164
RPL41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36019
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
regulation of glutamate uptake involved in transmission of nerve impulse	GO Biological Process Annotations 2023	1.0	null
Dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.544
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06505
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2341
RBBP5	ENCODE Transcription Factor Targets	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897252
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52239
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05488
Cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.146
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cul4A-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.359
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33156
amino acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.645
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7501
NPIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67303
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
hsa-miR-3675-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942303
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4888
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.194
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.349717
TPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21026
PMC8410083-elife-65574-fig7-data1.xlsx-KLF10_network-Unnamed_25_KLF10	Rummagene Transcription Factor Associations 2026	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.626273
hsa-miR-616	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ERP44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23484
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Memory Disorders	CTD Gene-Disease Associations	1.0	1.72884
IM-9	COSMIC Cell Line Gene Mutation Profiles	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18495
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
POMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42073
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.22469
Usher syndrome type 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.758
PPP4R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32402
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14571
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal dominant nonsyndromic deafness 48	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
ECHDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74593
r2 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18433
Hearing Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14256
Myosin VII complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
sensorineural hearing loss	MGI Mouse Phenotype Associations 2023	1.0	null
thyroid	GTEx Tissue Gene Expression Profiles	-1.0	-1.0201
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83496
Telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
Perturb_8949_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.1255
ANKRD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45092
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38313
Autosomal dominant auditory neuropathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.175
Telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.696
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1162
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82464
Recurrent axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.871
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral cortical neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05422
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39783
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.910882
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922517
PPARA_KO_GDS3748_516_mouse_Livers	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.55195
l-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
DDIT4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59285
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.017
brain	GeneRIF Biological Term Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22488
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338545
Symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.326
astroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.239913
A-CA-04-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.35564
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.086
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937218
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65456
neurotransmitter transport	GO Biological Process Annotations 2015	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14432
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09167
NCI-H1299	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37843
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59731
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41881
Hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.504
hsa-miR-3924	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Exophthalmos	CTD Gene-Disease Associations	1.0	1.07163
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71444
hair	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0655
ZNF718	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29376
intermediate stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9432
abnormal auditory brainstem response	IMPC Knockout Mouse Phenotypes	1.0	null
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.924
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851481
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8994
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
ADAM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70488
positive regulation of amino acid uptake involved in synaptic transmission	GO Biological Process Annotations 2025	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13344
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
abnormal inner hair cell synaptic ribbon morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09267
TMEM181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03732
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26599
Spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.375
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24795
GSE248858_5_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051637
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09018
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.682
GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.223
Neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.747
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.700863
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851601
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62686
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.19999
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.068837
Cocaine Abuse	DisGeNET Gene-Disease Associations	1.0	null
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.919
SKNDZ	CCLE Cell Line Gene Expression Profiles	1.0	3.40804
dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.955565
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917315
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37442
4-aminobutyrate transaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.692
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38235
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.063
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055462
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95318
SELENOF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24268
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00243
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-AAVH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86789
cytoskeletal calyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.271533
KLF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8213
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2014	1.0	null
CASZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86514
L-amino acid transport	GO Biological Process Annotations 2023	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Midbrain raphe nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.38713
Stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.98111
membrane potential driven uniporter activity	GO Molecular Function Annotations 2025	1.0	null
peripheral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.616183
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_10940_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.11207
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73377
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.05194
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828019
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040524
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.10353
Cranial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.587
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911835
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83792
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32524
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5457-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC5A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68375
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04531
Childhood absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12559
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FUS_02_124	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.70044
SOX9_01_309	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60266
regulation of acetylcholine uptake	GO Biological Process Annotations 2023	1.0	null
Status Epilepticus	CTD Gene-Disease Associations	1.0	1.03493
PANC1005	DepMap CRISPR Gene Dependency	1.0	2.33612
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
Postsynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.166
neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.27239
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neutropenia	CTD Gene-Disease Associations	1.0	1.07482
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
ZZEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0377
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3387
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
Perturb_10771_KO_Jnk2_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.58091
LIMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27188
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0337
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
vesicular	GeneRIF Biological Term Annotations	1.0	null
GSE248858_5_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ALPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70237
brain disease	GWASdb SNP-Disease Associations	1.0	0.168404
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.601
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4418_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7743
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.185
substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501965
Lateral amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
Granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.871
GSE62843,GSE64371_4_v_0_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
THNSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32999
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47184
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A623-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.716651
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01369
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30805
THEM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88385
Vasculitis, Leukocytoclastic, Cutaneous	CTD Gene-Disease Associations	1.0	1.04352
L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Usher syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
CL40	CCLE Cell Line Gene CNV Profiles	1.0	1.34829
modeling	GeneRIF Biological Term Annotations	1.0	null
TMEM88B_KD_GPL10558_471_human_cardiovascular progenitors cells differentiated from hES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879126
GSE158815_1_v_3_trib1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.217693
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50398
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.14955
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.551
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.05705
PARD6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07619
BMI1	ChEA Transcription Factor Targets	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.22274
APOBEC3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0602
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.764
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14609
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.368
Learning Disorders	CTD Gene-Disease Associations	1.0	1.46727
hematopoietic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838884
Gracilis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
GARRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81802
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942162
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2273
Neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.838
LMNTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
hsa-miR-4311	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.765296
DMAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10289
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83496
Cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.667
FNBP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48369
CHRDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24296
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.697
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.246
basal plate of m1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30958
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15274
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7909
lateral vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.604099
Dentate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13319
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04058
311 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
Tetanus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.472
Migraine with aura	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.606
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
RUNX1-17652178-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.62639
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71248
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01025
Neuroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
CA46	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47879
cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PPP6R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28427
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049375
CDC42EP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28326
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503058
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	2.04751
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73998
small intestine	HPA Tissue Gene Expression Profiles	1.0	1.63196
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.16119
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM86A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31676
developmental disorder of mental health	GWASdb SNP-Disease Associations	1.0	0.155372
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06741
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.869
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42719
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.313
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80574
CTCF	ENCODE Transcription Factor Targets	1.0	null
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55468
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
KYAE1	DepMap CRISPR Gene Dependency	1.0	4.29456
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.933
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967261
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74537
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.41063
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04741
abnormal mechanoreceptor morphology	MPO Gene-Phenotype Associations	1.0	null
GJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32838
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.41
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.075633
Autosomal recessive nonsyndromic deafness 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.445
GSE155305_2_v_1_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.266
CUX1	ChEA Transcription Factor Targets	1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08064
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96485
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75306
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
ZNF582	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16346
acidic amino acid transport	GO Biological Process Annotations 2015	1.0	null
decreased synaptic glutamate release	MGI Mouse Phenotype Associations 2023	1.0	null
modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.859258
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.362
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5177
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.721
A10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.546
Dendritic shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.656
GSE186654_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
USF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19076
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.695
Hypolemmal cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
Anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.577
Cerebellar granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.843
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78843
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19347
organelle part	GO Cellular Component Annotations 2015	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.762
MXI1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7734-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11111_KO_Tsc1/Cpt2_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34472
Hematopoietic stem cell_Bone marrow_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	2.4234
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8488
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBPJ	ChEA Transcription Factor Targets	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19736
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180185_7_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62793
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869868
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95376
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054578
Pons, behavioral state related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26786
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Secretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.686
periventricular stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61404
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91629
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01307
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13009
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	0.427231
ESRRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38277
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41178
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.805156
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837893
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5434
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	5.1357
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
Autosomal dominant nonsyndromic deafness 18	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.706
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38048
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.311
DUSP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41647
CTDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15524
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79003
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47288
P53-22127205-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WDR83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00417
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83396
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30078
abnormal cochlear IHC efferent innervation pattern	MGI Mouse Phenotype Associations 2023	1.0	null
Glutaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.698
Superior semicircular canal dehiscence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.75
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.803
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2604
Lung non-small cell carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.717
Outer hair cell_Inner Ear_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.11
AHSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22147
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897252
Brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.117
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18857
sodium ion transport	GO Biological Process Annotations 2015	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08615
Retinitis pigmentosa 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45267
GSE113106_0_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.732
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14786
Cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.703
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.655172
Presynaptic grid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
organic substance transport	GO Biological Process Annotations 2015	1.0	null
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03785
Medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.912
hsa-miR-1237	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00532
CORL105	DepMap CRISPR Gene Dependency	1.0	2.65718
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.867686
Sodium	HMDB Metabolites of Enzymes	1.0	null
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1892
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
CPTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65263
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040579
Autosomal recessive nonsyndromic deafness 74	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133213_9_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123372,GSE123373_1_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08121
Brain Lower Grade Glioma_LGG_TCGA-F6-A8O3-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149075_3_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11457_KO_Ezh2/Jak2_SRP075923	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.88892
abnormal colon morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Autosomal recessive nonsyndromic deafness 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
Cardiovascular Abnormalities	CTD Gene-Disease Associations	1.0	1.0561
Neuron projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.42104
abnormal adrenal gland morphology	IMPC Knockout Mouse Phenotypes	1.0	null
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30859
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dicarboxylic acid transport	GO Biological Process Annotations 2025	1.0	null
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30561
PPP1R16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00698
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52203
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Supporting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.089
Spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.946
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTF2B_01_362	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59561
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.831966
sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84655
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36814
metal ion transport	GO Biological Process Annotations 2015	1.0	null
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.98735
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
diagonal band	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447961
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.052363
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42194
abnormal synaptic transmission	MPO Gene-Phenotype Associations	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.69
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15321
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40248
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.148
DYNLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30951
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.068999
H2AC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29913
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46586
Retrosplenial area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49847
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.93311
external plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.344818
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
Hereditary neuropathy with liability to pressure palsies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063217
GSE207914_4_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11585
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.188022
MAP3K12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62414
ml3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.671
Cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.689
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
pathways	GeneRIF Biological Term Annotations	1.0	null
phosphate ion homeostasis	GO Biological Process Annotations 2023	1.0	null
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06779
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23496
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17019
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80987
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7126
hsa-miR-342-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
Autosomal dominant nonsyndromic deafness 17	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.165
ISTMES2	DepMap CRISPR Gene Dependency	1.0	2.27494
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trans-synaptic protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFILZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33012
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05147
GSE245270_2_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.238
GSE92434_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
Corticospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
LRRC32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52963
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.16
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.492848
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.812
Presynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Presynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
Perturb_11310_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.1388
axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.25917
GSE176093_0_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1464
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.14072
organic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Endolymphatic hydrops	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.61
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95184
BMI1-19503595-MEFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.991104
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.652
Posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.005029
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.577
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
Perturb_11332_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.55196
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
abnormal cochlear labyrinth morphology	MPO Gene-Phenotype Associations	1.0	null
sensory perception	GO Biological Process Annotations 2015	1.0	null
Cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.665
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92869
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27447
Autosomal recessive nonsyndromic deafness 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.498
UXS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57629
Endopeduncular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.524
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2768
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
NDEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84851
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.8
Organic anion transporters	Reactome Pathways 2014	1.0	null
Thrombocytopenia	CTD Gene-Disease Associations	1.0	1.01399
inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18706
Usher syndrome type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
IBA57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38436
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43031
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.06653
hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.498048
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81531
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17208
abnormal cochlear nerve compound action potential	MPO Gene-Phenotype Associations	1.0	null
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50257
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06903
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38704
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.23985
nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.775249
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Migraine without aura	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.388
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.678
GSE138863_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
intestine	GeneRIF Biological Term Annotations	1.0	null
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17776
cell projection	GO Cellular Component Annotations 2015	1.0	null
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48169
FUCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7411
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.52338
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.11138
GSE242290_1_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE241875_1_v_0_huwe1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRNAU1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62095
PHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82962
retinal ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.555956
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.091
neurotransmitter transport	GO Biological Process Annotations 2023	1.0	null
METTL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72314
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
dysfunction	GeneRIF Biological Term Annotations	1.0	null
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5018
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.99
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63489
NPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21727
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40972
NKX2-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27229
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.80928
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
OV90	CCLE Cell Line Gene Expression Profiles	1.0	1.37553
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28376
BHT101	DepMap CRISPR Gene Dependency	1.0	2.82729
specific developmental disorder	GWASdb SNP-Disease Associations	1.0	0.185553
AM38	DepMap CRISPR Gene Dependency	1.0	6.69946
abnormal scala media morphology	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38002
Entorhinal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08782
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01553
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_18Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.37413
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08457
Meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
Diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.397
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07736
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.837013
hsa-miR-1302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Striatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.281
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123069
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25133
RAB40C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93859
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48225
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.885
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49863
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11614
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30896
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
X-linked nonsyndromic deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
Endoplasmic reticulum cisternal network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21894
rheumatoid arthritis	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.052255
H2BC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62887
sub-surface cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.589
PDCD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00549
TNFSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58907
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17022
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11997
lateral part of the isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41691
Perturb_11912_KD_Arntl2_SRP063609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.33
lateral parabrachial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.929198
neoplasm of the skin	GWASdb SNP-Phenotype Associations	1.0	0.336278
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42454
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19437
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25073
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1247
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.853085
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
Compton-North congenital myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96181
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27881
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.490454
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cataract	MGI Mouse Phenotype Associations 2023	1.0	null
Axon hillock	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00565
Epibranchial	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52089
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.24465
Inflammation	CTD Gene-Disease Associations	1.0	1.8978
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
Lung squamous cell carcinoma_LUSC_TCGA-60-2697-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.97123
GSE95771_0_v_4_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94475
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.500664
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.35849
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.992
Glial cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07775
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.11303
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.98066
asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.06195
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23616
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.854
CCAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19971
hsa-miR-4735-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046256
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.5816
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1987
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.368
chloride channel activity	GO Molecular Function Annotations 2023	1.0	null
ZNF235	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43123
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8094
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.849
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
NR2F2_01_89	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59568
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05497
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0441
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.979895
Autosomal recessive nonsyndromic deafness 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.881
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.46251
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887957
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02525
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.762
MDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19672
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054882
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39563
Enlarged vestibular aqueduct	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37665
Vestibulocochlear nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.992268
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38637
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE138863_2_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91908
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0965
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73803
small intestine	GTEx Tissue Gene Expression Profiles	1.0	2.1364
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.040676
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.98572
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045438
SALL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85981
PCDHGC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49595
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05064
CARNS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79548
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.923339
KCNC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67102
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21012
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37594
COA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39842
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72901
abnormal colon morphology	IMPC Knockout Mouse Phenotypes	1.0	null
DCAKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12397
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.56928
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.133
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97691
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2286	CCLE Cell Line Gene CNV Profiles	1.0	1.76544
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42161
Perturb_4423_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.99267
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41809
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.898375
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74561
alpha-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
chloride transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
MESSA	CCLE Cell Line Gene Expression Profiles	1.0	1.48687
CL11	DepMap CRISPR Gene Dependency	1.0	5.84651
phosphate ion transport	GO Biological Process Annotations 2025	1.0	null
enhanced behavioral response to cocaine	MGI Mouse Phenotype Associations 2023	1.0	null
Cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.645
A-CA-04-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.02925
Synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
migraine	GWASdb SNP-Phenotype Associations	1.0	0.689964
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19911
pericellular basket	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.692078
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621428
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18779
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34181
Cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.74
tauopathy	GWASdb SNP-Disease Associations	1.0	0.500605
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC11551338-pnas.2411189121.sd01.xlsx-AHR-Unnamed_0_AHR	Rummagene Transcription Factor Associations 2026	1.0	null
Astrocyte projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.636
PCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00677
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.45518
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obsessive-compulsive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.48083
Focal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.94403
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955824
probucol_mus musculus_gpl9526_gds3619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056037
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056212
abnormal behavioral response to addictive substance	MPO Gene-Phenotype Associations	1.0	null
Hyperalgesia	DisGeNET Gene-Phenotype Associations	1.0	null
Superior vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.784
covered	GeneRIF Biological Term Annotations	1.0	null
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07598
Terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.533
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
hsa-miR-934	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28066
Hippocampal mossy fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.907
phosphate ion homeostasis	GO Biological Process Annotations 2025	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.72438
H3K27me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic anion transport	GO Biological Process Annotations 2015	1.0	null
hard palate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.74761
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01953
Multiple synapse bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
GSE108675_2_v_1_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614167
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.755891
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50163
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13356
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79507
interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.43616
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8168
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.08323
impaired behavioral response to xenobiotic	MPO Gene-Phenotype Associations	1.0	null
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29175
STAT3	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.88126
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56301
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.6196
hsa-miR-4446-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuron part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
single-organism localization	GO Biological Process Annotations 2015	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8519
absent cochlear nerve compound action potential	MPO Gene-Phenotype Associations	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8914
abnormal auditory brainstem response	MPO Gene-Phenotype Associations	1.0	null
Perturb_10939_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.43885
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30391
hsa-miR-1246	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
OCIP5X	DepMap CRISPR Gene Dependency	1.0	2.51063
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19425
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.227455
abnormal somatic sensory system morphology	MPO Gene-Phenotype Associations	1.0	null
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52623
laterodorsal tegmental nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405555
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64954
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
496100393_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.16693
cerebellar cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28201
hsa-miR-4769-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45157
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50398
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01107
TLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070606
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
lymphocytic leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067114
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.261599
abnormal hair cell morphology	MPO Gene-Phenotype Associations	1.0	null
S1PR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35939
TNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09588
CCDC85C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2567
SCC25	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56434
coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61004
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.38419
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57937
Brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.703
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51117
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.696
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
NEURL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66833
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
homology	GeneRIF Biological Term Annotations	1.0	null
MDAMB361	DepMap CRISPR Gene Dependency	1.0	4.8279
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PPP1CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97212
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H4C14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28202
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.807
auditory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
lateral wings of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.257
abnormal uterus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.922755
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.31277
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59695
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4917
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.685
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4639-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24776
musculoskeletal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.052255
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.152
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
ZFAND2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88926
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
brain	GTEx Tissue Gene Expression Profiles	1.0	1.0137
CGRRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20534
Perturb_4419_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.8674
AMPA glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.274
MAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63045
Septic Shock_Whole blood_GSE9692	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.65137
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CZ-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal cochlear inner hair cell physiology	MGI Mouse Phenotype Associations 2023	1.0	null
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.763
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.568
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35335
abnormal brain wave pattern	MGI Mouse Phenotype Associations 2023	1.0	null
amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MREG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80671
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal neuron morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF354B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55048
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28765
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.052255
Transport of small molecules	Reactome Pathways 2024	1.0	null
Usher syndrome type 2D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Lateral mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.911
SNU869	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21745
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0027
ZNF549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22694
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.949732
Dendriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Gene_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88519
Spine apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
Optic atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
hsa-miR-4652-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHMP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45458
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87991
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.968055
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
Squamous cell carcinoma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28233
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040192
Stereocilia coupling link	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.015
retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401765
Forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.699
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61987
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.42366
perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.565923
PEO4	DepMap CRISPR Gene Dependency	1.0	3.68
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887957
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Histaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.433
HAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35932
LCN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07215
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
FLI1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72338
22RV1	DepMap CRISPR Gene Dependency	1.0	6.9949
BEND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79365
auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.17249
Hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.441
Pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3
abnormal somatic nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
Perturb_10770_KO_Jnk1/Jnk2_SRP038635	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.745
NR3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98994
CAPAN1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.74001
TAOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65264
X-linked deafness 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55867
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.236
nitrogen compound transport	GO Biological Process Annotations 2015	1.0	null
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
abnormality of the biliary system	GWASdb SNP-Phenotype Associations	1.0	0.260943
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
SOGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68817
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16893
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891637
raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.49349
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.67206
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11083
RIOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49196
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.063665
TMEM59L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54809
DU145	CCLE Cell Line Gene Expression Profiles	1.0	2.13762
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.082
H2BC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59098
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05344
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRRM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99717
ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.952547
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
decreased cochlear hair cell number	MPO Gene-Phenotype Associations	1.0	null
Parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.688
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53947
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11485_KO_Mir183_SRP107957	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.39613
hsa-miR-548an	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02601
perinuclear theca	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.219969
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32354
RBM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79558
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34334
GSE141453,GSE141454_0_v_4_card11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
decreased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
P12ICHIKAWA	CCLE Cell Line Gene Expression Profiles	1.0	1.46874
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2909
SNU387	CCLE Cell Line Gene Expression Profiles	1.0	1.57887
abnormal hearing electrophysiology	MPO Gene-Phenotype Associations	1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.850206
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32121
Chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.122
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.419
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61021
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.919
Perisynaptic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.167
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6007
Brain_CT2_Inh L5-6 SST KLHL1	HuBMAP ASCT+B Annotations	1.0	null
Perirhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9746
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163317
Connexin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.219
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03841
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95307
Glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226411
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.816
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80984
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40991
anion transport	GO Biological Process Annotations 2015	1.0	null
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51262
LAMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25895
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87475
SET2	CCLE Cell Line Gene Expression Profiles	1.0	1.56316
Sessile serrated adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.533
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53947
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13891
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81658
DMRT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7363
GSE125007,GSE125008_6_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891637
Autosomal dominant nonsyndromic deafness 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44207
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.748
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10415
Cortical cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.073
encodes	GeneRIF Biological Term Annotations	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11497
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92534
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE143782_7_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11107_KO_Cpt2_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
TE4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48129
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54881
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null