association	dataset	threshold value	standardized value
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Dinoprost	CTD Gene-Chemical Interactions	1.0	null
Streptococcal Infections	CTD Gene-Disease Associations	1.0	1.31297
Lupus erythematosus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
Acute kidney tubular necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.659
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.50294
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13263
acceleration	GeneRIF Biological Term Annotations	1.0	null
quaternary ammonium group transport	GO Biological Process Annotations 2015	1.0	null
APOBEC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30235
COLO849	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72227
PAX6	ChEA Transcription Factor Targets	1.0	null
Methotrexate	DrugBank Drug Targets	1.0	null
LRCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55599
response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.06425
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12217
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14471
EFM19	DepMap CRISPR Gene Dependency	1.0	5.06303
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80461
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99949
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13384
sublayer 6b of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14012
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00559
NOP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15218
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50068201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31613
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3117-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
PMC9396374-Table_4.XLSX-AR_related_target_genes-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PRRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43359
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.089361
PROBENECID	DGIdb Drug Targets 2026	1.0	1.98495
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47633
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9055
diseases	GeneRIF Biological Term Annotations	1.0	null
polymorphismsnps	GeneRIF Biological Term Annotations	1.0	null
MT1M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00407028
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38029
H3K27me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cell plate	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.821
Folate transport and metabolism	KEGG Pathways 2026	1.0	null
GSE150072,GSE169209_4_v_11_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31783598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20441
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.591
plasma membrane region	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4725-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2646
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
VASN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60564
POU4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39171
BRD-K40016301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28876
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GSE206400_3_v_4_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dehydroepiandrosterone Sulfate	CTD Gene-Chemical Interactions	1.0	null
CNPY4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38773
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87216
BRD-K12460566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86618
Apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K35527855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21175
BRD-K40143134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01978
Capillary cell_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BV-173	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.079
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01367
SOX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59313
Nausea	CTD Gene-Disease Associations	1.0	1.87376
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046713
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRK-49F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991407
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55882
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59402
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Hearing Loss	CTD Gene-Disease Associations	1.0	1.48196
epigenetic	GeneRIF Biological Term Annotations	1.0	null
OTX2_KO_GDS4440_424_mouse_brain (fourth ventricular choroid plexus)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCIH1693	DepMap CRISPR Gene Dependency	1.0	2.65198
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04144
brain cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.087125
Vanilmandelic Acid	CTD Gene-Chemical Interactions	1.0	null
stably	GeneRIF Biological Term Annotations	1.0	null
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26078
NIPBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70421
EIF4EBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83481
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PI-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.55817
Oxytetracycline	DrugBank Drug Targets	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.883407
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952961
DoTc2-4510	GDSC Cell Line Gene Expression Profiles	1.0	1.71193
EZR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76977
BJHTERT	CCLE Cell Line Gene Expression Profiles	1.0	1.61034
cerebral infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325916
superficial stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87869
THP-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.449
Neoplasms	CTD Gene-Disease Associations	1.0	1.81393
Glucose transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.266
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86442
Urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.954
TFRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26592
BRD-K96522482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07739
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Agranulocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
H2BK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08659
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15902281-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
Viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.76
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.72
OTX2_KO_GSE27630_51_mouse_brain (fourth ventricular choroid plexus, E13)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Ventricular Dysfunction, Left	CTD Gene-Disease Associations	1.0	1.12426
VMCUB1	CCLE Cell Line Gene CNV Profiles	1.0	2.38851
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1207-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.719
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.60758
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29R-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905909
Familial juvenile hyperuricemic nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.71797
Rheumatoid arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
ERLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36391
TSEN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22166
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.769539
GGNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39014
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.75505
Arachnoid barrier layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.756
single-organism process	GO Biological Process Annotations 2015	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_1_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHP-134	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.725
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80478
PMC11399095-44161_2024_532_MOESM14_ESM.xlsx-Sheet1-Supplementary_Table_13_DEG_in_the_AA_borderzone_in_AF_vs_SR_patients_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PK8	DepMap CRISPR Gene Dependency	1.0	2.2019
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0766
GFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94978
BRD-K98749544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32113
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04218
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81904
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70255
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040107
Meningitis	CTD Gene-Disease Associations	1.0	1.10769
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.098206
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.719
MOSMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86251
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.239197
BRD-K03697080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17112
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226667
ISL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31339
Oculocerebrorenal Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32022
GJA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01297
PRPSAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29884
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63666
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CBX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87273
BRD-K83895653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36471
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.03535
Basal part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
SMAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07061
Methoxsalen	CTD Gene-Chemical Interactions	1.0	null
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
GOLGA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38285
LMO2	ChEA Transcription Factor Targets	1.0	null
BRD-A84764193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47983
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
uremia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.707961
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82981
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GO-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52279
osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237513
Endothelial microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38062
Ranitidine	DrugBank Drug Targets	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
tenoxicam	CTD Gene-Chemical Interactions	1.0	null
CDH4-35650610-MESC-MOUSE-STEM-AUTISM	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane region	GO Cellular Component Annotations 2015	1.0	null
r6 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07104
Diclofenac	CTD Gene-Chemical Interactions	1.0	null
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.932
TXNDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83454
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045321
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09308
Hearing Loss, Sensorineural	CTD Gene-Disease Associations	1.0	1.31536
responses	GeneRIF Biological Term Annotations	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
HCC1395	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83189
Brain Diseases	CTD Gene-Disease Associations	1.0	1.96566
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIA1_KO_GSE54418_261_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16644
FOXD4L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47183
PITPNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07627
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3685
3,4-Dihydroxyphenylacetic Acid	CTD Gene-Chemical Interactions	1.0	null
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
BRD-K03662481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50758
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79293
Ficusin	CTD Gene-Chemical Interactions	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91233
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.462626
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4535	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
BRD-K64860451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10519
GSE158320,GSE183351_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.052
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19591
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.554925
SALE	CCLE Cell Line Gene Expression Profiles	1.0	1.78188
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80446_0_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22443
ADM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73023
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.80656
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66896657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03526
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VG-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icosanoid transport	GO Biological Process Annotations 2023	1.0	null
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.728
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00216
BRD-K29702569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61798
Influenza	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22924
BRD-K79481905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05616
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10079833-41467_2023_37542_MOESM11_ESM.xlsx-Sheet1-Supplementary_Data_10_Significantly_differentially_expressed_genes_identified_in_IGF2BP1-KD_cells_compared_to_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
nephrectomized	GeneRIF Biological Term Annotations	1.0	null
Abdominal Pain	CTD Gene-Disease Associations	1.0	1.75993
Anaphylaxis	CTD Gene-Disease Associations	1.0	1.61851
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886613
dna	GeneRIF Biological Term Annotations	1.0	null
using	GeneRIF Biological Term Annotations	1.0	null
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.07482
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2979
hsa-miR-4271	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K10798676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10999
extracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1921
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
Ataxia	CTD Gene-Disease Associations	1.0	1.23837
Colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
Primary visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11781
BRD-K69671285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62689
contributes	GeneRIF Biological Term Annotations	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
blood-brain barrier	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.625
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02912
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02755
EPHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15324
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.698223
increased circulating creatinine level	IMPC Knockout Mouse Phenotypes	1.0	null
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41296
ACSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22351
Human brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
such	GeneRIF Biological Term Annotations	1.0	null
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2563
Tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.037
Diclofenac	DrugBank Drug Targets	1.0	null
Indomethacin	DrugBank Drug Targets	1.0	null
t59-kidney_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.59282
KATOIII	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12594
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9126
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1795
SMTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95441
pituitary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959113
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45229
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.16298
Inflammation	CTD Gene-Disease Associations	1.0	2.37053
BRD-K76539747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07006
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	42.1506
BRD-K16754572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01499
CEFACLOR ANHYDROUS	DGIdb Drug Targets 2026	1.0	0.389206
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.34459
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.07696
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.328
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	Reactome Pathways 2014	1.0	null
Myocarditis	CTD Gene-Disease Associations	1.0	1.31536
Kidney Failure, Acute	DisGeNET Gene-Disease Associations	1.0	null
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28942
Subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.776
BRD-K17060750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56153
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	1.80239
hoat3	GeneRIF Biological Term Annotations	1.0	null
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052672
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.48553
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
Piriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14012
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-182	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K99028283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05436
RDES	CCLE Cell Line Gene CNV Profiles	1.0	1.46491
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.728
NCIH82	CCLE Cell Line Gene Expression Profiles	1.0	3.40796
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
vmax	GeneRIF Biological Term Annotations	1.0	null
BRD-K40116023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83547
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.513
antiporter activity	GO Molecular Function Annotations 2025	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46369
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGFB1I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33031
Cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.773
Liver Cirrhosis, Experimental	DisGeNET Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.74565
Lens nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07965
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37993
Lesch-Nyhan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
Allan-Herndon-Dudley syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
Pulmonary Edema	CTD Gene-Disease Associations	1.0	1.7315
explains	GeneRIF Biological Term Annotations	1.0	null
HSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86488
SUGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46343
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04892
hsa-miR-4534	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.18094
inorganic anion exchanger activity	GO Molecular Function Annotations 2015	1.0	null
Nephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10282
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.575
TCF12_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.904978
BRD-K03496358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06116
Primary motor area, Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24616
BRD-K32191695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36726
GSE195513_2_v_1_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Taurocholic Acid	DrugBank Drug Targets	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84097
Piriform area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1882
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.59755
General substrate transporter	InterPro Predicted Protein Domain Annotations	1.0	null
hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.835198
vice	GeneRIF Biological Term Annotations	1.0	null
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92081
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29694
Ascites	CTD Gene-Disease Associations	1.0	1.68019
BRD-K90571714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62363
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85278
ZFAND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31598
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70298
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24591
CEPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12015
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.9592
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
Anterior cingulate area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62001
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC48A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17293
PRKCA_KO_GDS2141_300_mouse_small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.51997
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89788
Delirium	CTD Gene-Disease Associations	1.0	1.12219
ok cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.467273
THAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66462
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MO-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7266
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22779
MOLT16	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54211
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2721
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44011
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Drug-Induced Liver Disease	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65792
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.007
Gout	CTD Gene-Disease Associations	1.0	1.04051
BICR6	DepMap CRISPR Gene Dependency	1.0	4.75857
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.358
Esophageal Neoplasms	CTD Gene-Disease Associations	1.0	1.19379
IDI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00707
hsa-miR-4763-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
RICTOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52878
Ulcer	CTD Gene-Disease Associations	1.0	1.20654
oat	GeneRIF Biological Term Annotations	1.0	null
Hydroxyisourate hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.597
hsa-miR-3612	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07894
pravadoline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67432
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.924
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52317
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055786
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.90089
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83792
DNAJC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37844
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	1.71758
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5213
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39111
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21792
retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.087508
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.025
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18196
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A5RQ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.097
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
should	GeneRIF Biological Term Annotations	1.0	null
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79341
Liver Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59405
min	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09464
quaternary ammonium group transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.29496
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.876
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.15122
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8437
Quinidine	DrugBank Drug Targets	1.0	null
capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.895195
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0239
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51201
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05245
NCI-H82	GDSC Cell Line Gene Expression Profiles	1.0	3.60177
Anti-Inflammatory Agents	CTD Gene-Chemical Interactions	1.0	null
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.28049
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66186
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70298
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31487
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
PMC3438361__F2	PFOCR Pathway Figure Associations 2024	1.0	null
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37797
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
CTTNBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
amide transport	GO Biological Process Annotations 2015	1.0	null
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68804
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92754
GI1	CCLE Cell Line Gene Expression Profiles	1.0	1.86552
LANSOPRAZOLE	DGIdb Drug Targets 2026	1.0	0.254481
BRD-K83699731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29275
SAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37969
LIMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66711
SK-OV-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53535
Vascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
due	GeneRIF Biological Term Annotations	1.0	null
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69199
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.735
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Piroxicam	DrugBank Drug Targets	1.0	null
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.076
their	GeneRIF Biological Term Annotations	1.0	null
peptide transport	GO Biological Process Annotations 2015	1.0	null
AGMAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66048
sulfur compound transport	GO Biological Process Annotations 2015	1.0	null
U-266	GDSC Cell Line Gene Expression Profiles	1.0	2.18707
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.86
responsible	GeneRIF Biological Term Annotations	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1151
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36697652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14659
CEPHALOTHIN	DGIdb Drug Targets 2026	1.0	0.330825
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
treating	GeneRIF Biological Term Annotations	1.0	null
EIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.44772
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90385
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	3.15008
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3328
response to organic cyclic compound	GO Biological Process Annotations 2015	1.0	null
NCIH1568	DepMap CRISPR Gene Dependency	1.0	2.16064
Stomach Diseases	CTD Gene-Disease Associations	1.0	1.62758
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A4BK-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93380196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23892
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
SF295	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50004
hsa-miR-18a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
organic	GeneRIF Biological Term Annotations	1.0	null
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490619
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17519
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.48736
ZNF410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14693
KLHL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3847
BRD-K38955287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23412
SNU449	CCLE Cell Line Gene Expression Profiles	1.0	2.07431
response to acid chemical	GO Biological Process Annotations 2015	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54368
BRD-K87794979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0869
SLC25A34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84461
HELA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.94584
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6364
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2897
hsa-miR-1258	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38184
Fibrosis, Liver	DisGeNET Gene-Disease Associations	1.0	null
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31087
Peptic Ulcer	CTD Gene-Disease Associations	1.0	1.24935
NCI-H650	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE164306_5_v_0_tsc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
Hyperuricemia	DisGeNET Gene-Disease Associations	1.0	null
496100670_TCx_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5242
Infertility, Male	CTD Gene-Disease Associations	1.0	1.32192
BRD-K56106571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05334
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8D-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_WT_3T3_ONLY_1626_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
Influenza, Human	CTD Gene-Disease Associations	1.0	2.88009
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20985
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.678571
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
organic anion transport	GO Biological Process Annotations 2015	1.0	null
CACO-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.977
ACSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
Acute Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3169	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79673
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
CIITA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051066
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.826523
SDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63547
expressing	GeneRIF Biological Term Annotations	1.0	null
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27013
Anemia, Hemolytic, Autoimmune	CTD Gene-Disease Associations	1.0	1.81111
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87731
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Psoriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11679
binding	GO Molecular Function Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82442
molecular	GeneRIF Biological Term Annotations	1.0	null
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9467
PNKD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53877
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.301976
6-Mercaptopurine	CTD Gene-Chemical Interactions	1.0	null
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20627
Choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.269
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MC116	CCLE Cell Line Gene Expression Profiles	1.0	1.80267
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Fever	DisGeNET Gene-Phenotype Associations	1.0	null
Sugar transporter, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0326
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96248
apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.368536
concerted	GeneRIF Biological Term Annotations	1.0	null
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.362
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2524
PNRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19149
Osteomyelitis	CTD Gene-Disease Associations	1.0	1.21076
PMC4784386__F5	PFOCR Pathway Figure Associations 2024	1.0	null
AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.956
Psp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
PRR22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8394
PMC4122637__F3	PFOCR Pathway Figure Associations 2023	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33075
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.14694
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.79484
organic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K37000177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74024
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2922
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8543
MAEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87154
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50611
Piroxicam	CTD Gene-Chemical Interactions	1.0	null
Perturb_4481_KO_Prdm12_SRP307995	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.22684
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
ABHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39326
BRD-K64970964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1875
BRD-K22474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17024
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.76632
endocytosis	GeneRIF Biological Term Annotations	1.0	null
basolateral plasma membrane	GO Cellular Component Annotations 2023	1.0	null
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20523
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8445
GNAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4069
Hyperalgesia	CTD Gene-Disease Associations	1.0	1.93444
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.64865
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
RAD21	ENCODE Transcription Factor Targets	1.0	null
MYORG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53419
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.275445
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5018
BRD-K20024676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51088
ERG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23452
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52188
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12003
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Indomethacin	CTD Gene-Chemical Interactions	1.0	null
Vaginal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
stimulated	GeneRIF Biological Term Annotations	1.0	null
BLCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8817
hoats	GeneRIF Biological Term Annotations	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0675
ALS2CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77012
injury	GeneRIF Biological Term Annotations	1.0	null
SEC14L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19325
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.40849
basolateral	GeneRIF Biological Term Annotations	1.0	null
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01637
oat1	GeneRIF Biological Term Annotations	1.0	null
plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.008503
bartter disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.270464
Hypertrophy	CTD Gene-Disease Associations	1.0	1.76481
protein kinase binding	GO Molecular Function Annotations 2015	1.0	null
Interstitial nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.894
Fanconi-like syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65115
NCI-H1693	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K44244207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24916
MRK-nu-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48722
MKN7	GDSC Cell Line Gene Expression Profiles	-1.0	-2.38305
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.35234
BRD-K74688087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40064
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Oxalic Acid	DrugBank Drug Targets	1.0	null
LZTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3503
CRCGN015_MCF10A_48H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42012
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
BRD-K76515685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26355
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.094359
pharmacogenomic	GAD High Level Gene-Disease Associations	1.0	0.300704
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0825
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223419
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4996
STX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20375
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dyspnea	CTD Gene-Disease Associations	1.0	1.38384
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039977
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K06117861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44481
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cefazolin	CTD Gene-Chemical Interactions	1.0	null
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85632
Berry	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
CYP20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96382
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53953
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2152
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08859
septopallidal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18689
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886613
BRD-K80622681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03459
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57636
Epilepsy, Tonic-Clonic	CTD Gene-Disease Associations	1.0	1.03493
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
kinase binding	GO Molecular Function Annotations 2015	1.0	null
RBM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50207
RPL26L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20401
arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.324094
BRD-K93900188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03828
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8054
BRD-A62469171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28685
PNMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33087
antiporter activity	GO Molecular Function Annotations 2015	1.0	null
VDAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10976
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57021
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cholic Acid	DrugBank Drug Targets	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.1522
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20407
Aciclovir	DrugBank Drug Targets	1.0	null
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.087
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
MAN2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45807
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4296
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Thrombosis	CTD Gene-Disease Associations	1.0	1.42428
MYC_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A01717111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04938
Nephrolithiasis_Kidney_GSE10162	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45894
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80006
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	7.00268
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.192266
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.187
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00216
ZR751	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6656
serous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.572418
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
EMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05728
Cervicovaginal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10853
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
SFXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85499
abnormality of adipose tissue	GWASdb SNP-Phenotype Associations	1.0	0.919744
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RAB11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40808
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36776
Taenia tecta, ventral part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51297
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02776
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.924
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27853
ETS1	ENCODE Transcription Factor Targets	1.0	null
Peripheral Nervous System Diseases	CTD Gene-Disease Associations	1.0	2.88009
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02261
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A70931301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44815
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.6709
CCK81	DepMap CRISPR Gene Dependency	1.0	2.91643
BRD-K82409466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24933
Perturb_13746_OE_Fezf2_SRP267548	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.47078
RBBP5	ENCODE Transcription Factor Targets	1.0	null
alphaketoglutarate	GeneRIF Biological Term Annotations	1.0	null
renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.362609
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19672435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98503
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
Myeloid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7038
bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.789262
Liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.46
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLHL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50175
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CDC42	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00394369
PDCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.0363
Anemia	CTD Gene-Disease Associations	1.0	2.13931
BRD-K72787967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56567
urinary	GeneRIF Biological Term Annotations	1.0	null
icosanoid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094228
Renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
variations	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LARP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93172
Pancytopenia	CTD Gene-Disease Associations	1.0	1.3639
PRDM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75604
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17519
REXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.087
SOHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51278
S2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.321
EW-16	GDSC Cell Line Gene Expression Profiles	1.0	1.84896
elucidation	GeneRIF Biological Term Annotations	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40937
Contact dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
Fluorouracil	CTD Gene-Chemical Interactions	1.0	null
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44104
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.432
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0155
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238108
GSE230283_1_v_0_birc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Blood microparticle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.237
reference	GeneRIF Biological Term Annotations	1.0	null
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GATA2_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oat3	GeneRIF Biological Term Annotations	1.0	null
Chemical And Drug Induced Liver Injury	DisGeNET Gene-Disease Associations	1.0	null
HCMEC/D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
compared	GeneRIF Biological Term Annotations	1.0	null
BRD-K35724671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32918
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38344
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic anion transport	GO Biological Process Annotations 2025	1.0	null
ochratoxin A	CTD Gene-Chemical Interactions	1.0	null
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.995
VASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92707
Otx2_KO_GDS4440_143_mouse_fourth ventricular choroid plexus tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cuboid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447961
solute:inorganic anion antiporter activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K98505253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42102
nsaids	GeneRIF Biological Term Annotations	1.0	null
Chemically-Induced Liver Toxicity	DisGeNET Gene-Disease Associations	1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060334
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0802
BRD-K09777330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.75254
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6319
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9786
brain endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.184434
KDM5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29246
Azotemia	CTD Gene-Disease Associations	1.0	1.90242
BRD-K12683022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19442
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16632
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836593
enzyme binding	GO Molecular Function Annotations 2015	1.0	null
depression	GWASdb SNP-Phenotype Associations	1.0	0.35654
YWHAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80493
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HuCCT1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.92868
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.35894
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12347309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66105
intermediate stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06938
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94431
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975501
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 1	HuBMAP ASCT+B Annotations	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265381
urine	GeneRIF Biological Term Annotations	1.0	null
leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185525
exocrine acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179408
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-P6-A5OF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.487407
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03901
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.48702
E2A_Deficiency_GDS5084_271_mouse_DN2 thymocyte	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
a24	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.63
Tenofovir	DrugBank Drug Targets	1.0	null
Diazinon	CTD Gene-Chemical Interactions	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.663
response to organic substance	GO Biological Process Annotations 2015	1.0	null
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
BRD-K41561756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21881
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11181
UACC893	DepMap CRISPR Gene Dependency	1.0	2.1854
perfluorooctanoic acid	CTD Gene-Chemical Interactions	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3056
Tetracycline	CTD Gene-Chemical Interactions	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.989926
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876393
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.833118
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.228
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.942
Perturb_8628_KO_Pyk2_SRP329328	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-15.1348
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69741
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
versa	GeneRIF Biological Term Annotations	1.0	null
Extrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
CTCF	ENCODE Transcription Factor Targets	1.0	null
EBAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73732
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.95324
TBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43888
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.505
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
CAMA1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01268
CDK2AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83059
11906190-Table2a-1	GeneSigDB Published Gene Signatures	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE184902_3_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PIK3R4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99065
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1166
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039728
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K44167510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59906
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.58291
ZNF43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20004
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
Bumetanide	CTD Gene-Chemical Interactions	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29804
Leber congenital amaurosis with early-onset deafness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
T3M3	DepMap CRISPR Gene Dependency	1.0	2.50242
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Human immunodeficiency virus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09135
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.399751
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
uptake	GeneRIF Biological Term Annotations	1.0	null
BRD-K02959126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04907
Hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48919
organic substance transport	GO Biological Process Annotations 2015	1.0	null
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04454
IL6ST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81258
Acute kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR4_01_132	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.93821
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	3.4256
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36259
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72251
LRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84591
Phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
PMC8265195__F3	PFOCR Pathway Figure Associations 2024	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
POLR2A	ENCODE Transcription Factor Targets	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
partly	GeneRIF Biological Term Annotations	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.38459
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.28248
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.904623
RNF40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00259
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17668
mood disorder	GWASdb SNP-Disease Associations	1.0	0.2873
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.61107
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K27472340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0181
Intrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
variant	GeneRIF Biological Term Annotations	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29552
Dehydroepiandrosterone	CTD Gene-Chemical Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81P-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04345
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Anterior cingulate area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69526
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04929
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67247
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.864361
DGKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25489
GSS	DepMap CRISPR Gene Dependency	1.0	2.17725
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20911
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66619
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24883
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071061
NR3C1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K67123444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32471
methoxytryptophol	CTD Gene-Chemical Interactions	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.415
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Lung Injury	CTD Gene-Disease Associations	1.0	1.12599
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68869
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11477
BRD-K45609222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27078
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.69251
CHO-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.967
BRD-K12067186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07713
Cephalosporins	CTD Gene-Chemical Interactions	1.0	null
BRD-K23232542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65048
Uric Acid	DrugBank Drug Targets	1.0	null
GSE152379_0_v_4_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41912
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2798
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
DMRT1	ChEA Transcription Factor Targets	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10751
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62987
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.05813
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4551
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HSC3	CCLE Cell Line Gene CNV Profiles	1.0	1.57299
tripeptide transport	GO Biological Process Annotations 2015	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064456
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92427
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.323365
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.006199
BRD-K16387460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2315
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K77634326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80152
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054644
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35918
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23657
Cephaloridine	CTD Gene-Chemical Interactions	1.0	null
BRD-K52854560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05276
anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992826
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04321
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1921
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19932
MT1X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96869
HS936T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40226
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.426
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7401
SLC44A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90578
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17039
KU812	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Traumatic brain injury	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19303
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15995
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.49558
female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050124
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42797038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93883
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0812
Mucositis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
Drug Eruptions	CTD Gene-Disease Associations	1.0	1.88995
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.49609
TSPAN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75252
MRPS31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49974
methylation	GeneRIF Biological Term Annotations	1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60377
pravastatin	GeneRIF Biological Term Annotations	1.0	null
glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.078436
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325187
Uric acid urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
DNLZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83132
COV318	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16265
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
BRD-K46739745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07395
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
LRP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19588
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96038
cellular process	GO Biological Process Annotations 2015	1.0	null
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
appears	GeneRIF Biological Term Annotations	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38665
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41154
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68043
BRD-K29144516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00315
response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.354422
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
leukemia	GeneRIF Biological Term Annotations	1.0	null
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GI-ME-N	GDSC Cell Line Gene Expression Profiles	1.0	1.46944
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
Baclofen	DrugBank Drug Targets	1.0	null
CRCGN015_MCF10A_48H:G18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12764
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66236
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243294
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01629
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9215
Skin Diseases, Viral	HuGE Navigator Gene-Phenotype Associations	1.0	null
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26996
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Aspartame	DrugBank Drug Targets	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76912
pravastatin kinetics	GAD Gene-Disease Associations	1.0	null
BRD-K27083306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29489
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77149
CENPW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82464
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918968
estradiol-17 beta-glucuronide	CTD Gene-Chemical Interactions	1.0	null
appear	GeneRIF Biological Term Annotations	1.0	null
Colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.772
MYH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16761
Fetal Death	CTD Gene-Disease Associations	1.0	1.1556
Anuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046856
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6907
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25113
18277965-Table4b	GeneSigDB Published Gene Signatures	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.042282
BRD-K33283629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70072
LMSU	CCLE Cell Line Gene CNV Profiles	1.0	1.77421
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.58351
SNU308	DepMap CRISPR Gene Dependency	1.0	2.42474
BRD-K05584347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.23446
BRD-K38748890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45763
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
hsa-miR-1207-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.26716
BRD3OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63027
Basal plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
HTC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.918269
oligopeptide transport	GO Biological Process Annotations 2015	1.0	null
lung	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060765
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.519
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00617
CJM	CCLE Cell Line Gene CNV Profiles	1.0	1.42603
C4orf48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63872
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44125
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.609735
SNU349	DepMap CRISPR Gene Dependency	1.0	4.50039
BRD-K34761198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78821
Pyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.453
BRD-K41326905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04452
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05341
Embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.887
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.408
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.322
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46537
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.359
including	GeneRIF Biological Term Annotations	1.0	null
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
Pravastatin	DrugBank Drug Targets	1.0	null
Ureteric bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
Cerebral Infarction	CTD Gene-Disease Associations	1.0	1.22112
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08248
trans-2-hydroxycinnamic acid	DrugBank Drug Targets	1.0	null
Glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.514
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.41963
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7307
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66475
PHF8-20622853-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.70255
proliferative diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.169812
modified amino acid transport	GO Biological Process Annotations 2015	1.0	null
BC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24184
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55051
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27566
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.380814
Posterior parietal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03243
MSTO211H	DepMap CRISPR Gene Dependency	1.0	2.35986
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46275
BRD-K68119260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4696
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.897
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.1014
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224398
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36372
BAG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54388
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6259
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46111
Polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.757
HIV Infections	HuGE Navigator Gene-Phenotype Associations	1.0	null
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03484
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.23137
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238406
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22344
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.26128
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZRANB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54555
ZNF480	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05141
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.6786
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01535
NKX6-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02165
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.844769
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
COLO-829	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.15156
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3869
pkcalpha	GeneRIF Biological Term Annotations	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
Weight Gain	CTD Gene-Disease Associations	1.0	1.13177
BRD-K91225366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6827
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF565	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59642
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.72738
PMC4122637__F3	PFOCR Pathway Figure Associations 2024	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20407
cefdinir	CTD Gene-Chemical Interactions	1.0	null
nadc3	GeneRIF Biological Term Annotations	1.0	null
Death	CTD Gene-Disease Associations	1.0	1.22696
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.9674
TGIF2LY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72595
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MORF4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82037
fatty acid transport	GO Biological Process Annotations 2025	1.0	null
Hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.323
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.864
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26805
Cefotaxime	DrugBank Drug Targets	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.185
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3903
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.26266
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46561246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49078
pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435289
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4934
MYC	ENCODE Transcription Factor Targets	1.0	null
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36259
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3268
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_12_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
Aortic smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4317_KO_Fmn2_SRP109283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.49755
establishment of localization	GO Biological Process Annotations 2015	1.0	null
ZNF624	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76894
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.1151
Fibrosis	CTD Gene-Disease Associations	1.0	2.00357
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.56006
Cholestasis	CTD Gene-Disease Associations	1.0	1.97376
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCA1_Knock-in_GDS3544_561_mouse_Cerebellum - 4 Weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LBHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
sulfate	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.1755
Bronchial Hyperreactivity	CTD Gene-Disease Associations	1.0	1.3039
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26185
prostaglandin transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Vasculitis	CTD Gene-Disease Associations	1.0	1.41229
PMC3734218__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.956
RAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64315
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47471281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.12
Testosterone	CTD Gene-Chemical Interactions	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.19742
Organic anion transport	Reactome Pathways 2024	1.0	null
MYC-19915707-AK7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
basomedial amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11904
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.4608
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952961
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bendroflumethiazide	CTD Gene-Chemical Interactions	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905909
TACC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29384
MN-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10152
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11641
nucleotide	GeneRIF Biological Term Annotations	1.0	null
NPEPPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85424
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66616
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-3.37247
Kidney Failure, Chronic	CTD Gene-Disease Associations	1.0	1.21337
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.843286
TGFBR2_knockout_296_GSE22989	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.92331
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K12035825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68274
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.159
Brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.228
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36938
BPGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62144
disease	GWASdb SNP-Disease Associations	1.0	0.028312
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26965
hepatic	GeneRIF Biological Term Annotations	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30859
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3J7-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Influenza	DisGeNET Gene-Disease Associations	1.0	null
Organic cation/anion/zwitterion transport	Reactome Pathways 2014	1.0	null
H2BK12ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
processes	GeneRIF Biological Term Annotations	1.0	null
COX8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32703
Penicillin G	CTD Gene-Chemical Interactions	1.0	null
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30426
antiporter activity	GO Molecular Function Annotations 2023	1.0	null
Capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.692085
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.59931
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16545
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-2.88893
dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36526
Myelomonocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
toxicity	GeneRIF Biological Term Annotations	1.0	null
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06962
TAL1_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78245984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12979
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.529
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49671
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.603
BRD-K28820796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61163
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.55802
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.63856
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54109
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56507
PEMETREXED DISODIUM	DGIdb Drug Targets 2026	1.0	0.275687
Endocarditis, Bacterial	CTD Gene-Disease Associations	1.0	1.06044
Nephron epithelial cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
Hypertension	HuGE Navigator Gene-Phenotype Associations	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053706
LN340	CCLE Cell Line Gene Expression Profiles	1.0	1.50244
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16127
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07283
IRF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31248
Integral component of synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
transport	GeneRIF Biological Term Annotations	1.0	null
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
LS-180 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.87733
HOP62	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42417
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.385
hsa-miR-4735-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31286
BRD-K45271289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83927
Glomerulonephritis	CTD Gene-Disease Associations	1.0	1.08762
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21673
BRD-K29903367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45726
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.134
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77735
excretion	GeneRIF Biological Term Annotations	1.0	null
bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21573
Hearing Disorders	CTD Gene-Disease Associations	1.0	1.45168
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69888
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SNX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18056
ECC12	GDSC Cell Line Gene Expression Profiles	1.0	2.5529
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88678
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.13471
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62991
Paresthesia	CTD Gene-Disease Associations	1.0	1.0241
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104954
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	2.03547
Headache	CTD Gene-Disease Associations	1.0	1.98039
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224893
TRAF3IP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57659
L-Carnitine	DrugBank Drug Targets	1.0	null
glutathione transport	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.92315
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H4K91ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158320,GSE183351_2_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12403
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.60432
increased circulating creatinine level	MGI Mouse Phenotype Associations 2023	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.69335
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
SAM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.833
DBTRG05MG	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67967
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
Tenoxicam	DrugBank Drug Targets	1.0	null
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
Obstructive jaundice	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
Bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.536
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.703536
led	GeneRIF Biological Term Annotations	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21792
SP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00329
SNU201	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46163
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3695
t-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11978
BRD-K23029982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11886
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
ZFTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27908
Hypertension	CTD Gene-Disease Associations	1.0	2.04541
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3174
Ebolavirus(EBOV)_5day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.77911
BRD-K00265832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79192
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
ceftibuten	CTD Gene-Chemical Interactions	1.0	null
Nephrosis, Lipoid	CTD Gene-Disease Associations	1.0	1.06515
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
transport across blood-brain barrier	GO Biological Process Annotations 2025	1.0	null
D-283MED	GDSC Cell Line Gene Expression Profiles	1.0	2.04782
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.960312
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54677
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.57083
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.824
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15397
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.982
Primary visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02438
Prelimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24233
TASOR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39955
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	8.80046
Diarrhea	CTD Gene-Disease Associations	1.0	1.90869
Gastric ulcer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30325
DFFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7804
VAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70224
clustering	GeneRIF Biological Term Annotations	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.083
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Hypotension	CTD Gene-Disease Associations	1.0	1.31416
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Acute Lung Injury	CTD Gene-Disease Associations	1.0	1.09047
hsa-miR-4456	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Aristolochic Acids	CTD Gene-Chemical Interactions	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.062
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Syncytiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
C1orf226	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39627
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.90342
membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.105294
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12405
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.23042
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73922
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24696
BRD-K01594854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30956
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
brain	GTEx Tissue Gene Expression Profiles	1.0	1.20374
BRD-K18724553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49569
Liotrix	DrugBank Drug Targets	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62142
PLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91263
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.13248
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17235
B-lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3612
SNX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31512
NR2C2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575234
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92441
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.50146
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
Chronic Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Liver epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
Perturb_10325_KO_Gsdmd_SRP318237	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.1232
Intestinal Diseases	CTD Gene-Disease Associations	1.0	1.18718
BRD-K37459038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05045
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6882
BRD-K51844455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23974
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.842715
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A729-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87167
HSC3	DepMap CRISPR Gene Dependency	1.0	3.95925
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15637
POU3F1-26484290-ESCSS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA1	ChEA Transcription Factor Targets	1.0	null
Ureter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
edaravone	GeneRIF Biological Term Annotations	1.0	null
TAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01655
ZNF594	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3464
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042843
IRF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34629
drug-related genes	GAD Gene-Disease Associations	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36129
Caki-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30375
BRD-K13526697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02905
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9199
GDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66327
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60968
DDX50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21569
Skin Diseases	CTD Gene-Disease Associations	1.0	1.37189
Fatty Liver	CTD Gene-Disease Associations	1.0	1.9742
PCI30	DepMap CRISPR Gene Dependency	1.0	2.42031
tissuespecific	GeneRIF Biological Term Annotations	1.0	null
BRD-K82930531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46708
renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
Nephritis, Interstitial	CTD Gene-Disease Associations	1.0	2.21303
nutrition disease	GWASdb SNP-Disease Associations	1.0	0.419335
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2673
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70022
SW1088	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K11404512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36158
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09103
SKMEL28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81479
TEAD4	ENCODE Transcription Factor Targets	1.0	null
Polyuria	CTD Gene-Disease Associations	1.0	1.63205
RAB11FIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20716
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60777
ZIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29788
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.501144
KD	DepMap CRISPR Gene Dependency	1.0	2.71173
BRD-K03056434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84628
NAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76978
acute kidney tubular necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203933
ST486	GDSC Cell Line Gene Expression Profiles	1.0	1.4883
markedly	GeneRIF Biological Term Annotations	1.0	null
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951843
Perturb_13736_OE_MYCL_SRP277794	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.96089
DHX34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93459
CTCFL	ENCODE Transcription Factor Targets	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.98497
respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402901
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6495
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39481
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
basolateral plasma membrane	GO Cellular Component Annotations 2025	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25271
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.844
ATXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94863
APOBEC3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3924
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97711
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
naltrindole-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.268
PMC8043114-Table_7.xlsx-PE1-gene_name_s_ETV3	Rummagene Transcription Factor Associations 2026	1.0	null
overnutrition	GWASdb SNP-Disease Associations	1.0	0.476572
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3360_KO_Bach2_SRP267100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43083
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
balkan nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.54393
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZF-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.850845
rabbit	GeneRIF Biological Term Annotations	1.0	null
PMC3438361__F2	PFOCR Pathway Figure Associations 2023	1.0	null
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28758
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27207
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.36889
PPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32475
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17552
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 2	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GSE101239_4_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Uric acid nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.039298
ZMYM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34683
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.15931
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.22435
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78681
extrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.21782
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41711
Apical plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LDLRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54042
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88613
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.883126
Rhizome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.211
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37447
C6orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61602
RIF1_KD_GDS4943_13_mouse_J1 ESC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
superior	GeneRIF Biological Term Annotations	1.0	null
BRD-K28165728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2992
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
EIF2AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10596
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Colorectal Neoplasms	CTD Gene-Disease Associations	1.0	1.20558
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.65091
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3902
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60108
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.113
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.682148
respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118781
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85894
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3675-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46537
primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13028
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838291
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.977
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56179
Hyperplasia	CTD Gene-Disease Associations	1.0	2.01363
prevent	GeneRIF Biological Term Annotations	1.0	null
Melatonin	DrugBank Drug Targets	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.34
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975501
Stevens-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.366
BRD-K42145213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49413
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72050003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04337
H290	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26866198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01695
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma	CTD Gene-Disease Associations	1.0	1.43401
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.245
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50124
PANC-10-05	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65981
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
EW8	CCLE Cell Line Gene Expression Profiles	1.0	1.57282
MRPL55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61702
TWIST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32192
WWC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64981
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Doxycycline	DrugBank Drug Targets	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.9394
Stroke	CTD Gene-Disease Associations	1.0	1.21567
Respiratory Tract Infections	CTD Gene-Disease Associations	1.0	1.33199
Furosemide	CTD Gene-Chemical Interactions	1.0	null
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
BRD-K67007076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02014
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ALKBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58052
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47288
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4892
CD37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77802
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.321
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30194
ZBTB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33342
PYCR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1783
Urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.787
Hemolytic-Uremic Syndrome	CTD Gene-Disease Associations	1.0	1.17794
glomerular	GeneRIF Biological Term Annotations	1.0	null
Colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.77
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Posterior parietal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05491
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Quercetin	CTD Gene-Chemical Interactions	1.0	null
RYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41114
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.085
BRD-K07615667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93847
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
BRD-K01951210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82256
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58192
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9362
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66438
Stomach Ulcer	CTD Gene-Disease Associations	1.0	1.6192
TCMK-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.603
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
inorganic anion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42959
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4728
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.65294
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49369
variation	GeneRIF Biological Term Annotations	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
interstitial nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.241895
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8552
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00405
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6137
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
drug	GeneRIF Biological Term Annotations	1.0	null
PENICILLIN G POTASSIUM	DGIdb Drug Targets 2026	1.0	1.65412
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
filtration	GeneRIF Biological Term Annotations	1.0	null
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77599
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.088
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51814
prostaglandin transport	GO Biological Process Annotations 2025	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18944
Adefovir Dipivoxil	DrugBank Drug Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CELSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62219
Vasculitis, Leukocytoclastic, Cutaneous	CTD Gene-Disease Associations	1.0	1.474
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.6
hypertension	GeneRIF Biological Term Annotations	1.0	null
Posterior parietal association areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1513
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.95417
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74553
maximum	GeneRIF Biological Term Annotations	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09196
stomach	GTEx Tissue Gene Expression Profiles	1.0	0.897993
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25502
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19493
BRD-K42126874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42606
Portio vaginalis cervicis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
A-CA-04-2009(H1N1)_12Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.43741
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.091
Plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.647
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13006
EWSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77336
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
PPARGC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83415
Taurocholic Acid	CTD Gene-Chemical Interactions	1.0	null
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.79079
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.896
Hepatomegaly	CTD Gene-Disease Associations	1.0	2.02627
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.72557
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42989
cerebellar cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903342
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRRC10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37977
pRb_Deficiency_GDS3176_605_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
ZNF334	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7893
BRD-K57138551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96888
PGR-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A78982410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36033
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997295
NCIH1581	DepMap CRISPR Gene Dependency	1.0	2.10273
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7054
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30868
AGTRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09838
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.159268
IDH3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00593046
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.96
Cefadroxil	DrugBank Drug Targets	1.0	null
Liddle syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
proximal	GeneRIF Biological Term Annotations	1.0	null
NUAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24952
BRD-K07591847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19841
MED15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7141
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.999
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
FU97	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Oseltamivir	DrugBank Drug Targets	1.0	null
substrate	GeneRIF Biological Term Annotations	1.0	null
BRD-K00377328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48838
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.761
Meningitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8536
Pars recta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41906
Acute pyelonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.428
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951843
BRD-K09108485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38411
C10orf95	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34634
BRD-K48533326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59952
BRD-K44307624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14279
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.90089
Lymphoid leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416521
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449886
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2297
BRD-K84935293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1931
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099017
ICC12	DepMap CRISPR Gene Dependency	1.0	2.62263
Coffin-Siris syndrome 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
ITPKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62407
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28289
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.777
ZNF286A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.184
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80625
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.35596
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97711
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13355
exosome (rnase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.191777
septostriatal part of the olfactory tuberculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87602
TCF4	ChEA Transcription Factor Targets	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.64283
Proximal convoluted tubular cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9128
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.182221
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-2.77001
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75299
Cardiomyopathies	CTD Gene-Disease Associations	1.0	1.5143
intrahepatic cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158605
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249006
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
PRKAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3285
MYC-19915707-AK7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33307
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58217
cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.179802
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.084
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	2.15588
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57039
gout	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.808949
Intrinsic component of synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
Parenchymal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00015
BT-474	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
UQCRQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78244
OMEPRAZOLE	DGIdb Drug Targets 2026	1.0	0.194603
RNASE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47218
B-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4147
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.723472
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	2.11105
Acquired immunodeficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.113
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9
abnormal urine homeostasis	MPO Gene-Phenotype Associations	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.962617
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.196
PL-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70111
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4763-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
sublayer 6b of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07291
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
Perturb_562_KD_LMO1_SRP158473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.531
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06815
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72269
Diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AST 120	CTD Gene-Chemical Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063506
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74984
Proteinuria	CTD Gene-Disease Associations	1.0	2.21013
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ALG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58974
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49222
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.11186
Kidney papillary necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18596
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61582
clearance	GeneRIF Biological Term Annotations	1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8605
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8198
SNU1214	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11615
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17372
MEIOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14226
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58025
SYK_knockdown_190_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.378
GSE151782_6_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
Organic cation/anion/zwitterion transport	Reactome Pathways 2024	1.0	null
BRD-K53121826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75549
HIGD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20207
BRD-K71605668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07172
MC1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13001
APP_KO_GDS4414_370_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MOLP8	CCLE Cell Line Gene CNV Profiles	1.0	1.34604
Proximal tubule cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
laminin-11 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.708
MKN28	GDSC Cell Line Gene Expression Profiles	-1.0	-2.14178
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
Hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Cefoperazone	DrugBank Drug Targets	1.0	null
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
BRD-K89650689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0365
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.48566
angelicin	CTD Gene-Chemical Interactions	1.0	null
pharmacotherapeutic	GeneRIF Biological Term Annotations	1.0	null
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62171
HOXC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28692
extracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.117557
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02431
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56446
ZNF526	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69173
some	GeneRIF Biological Term Annotations	1.0	null
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08372
BRD-K67873600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02876
TMCO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46299
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952961
tubular	GeneRIF Biological Term Annotations	1.0	null
BRD-K36352298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74462
Edema	CTD Gene-Disease Associations	1.0	2.22338
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21937
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29162
hsa-miR-650	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82532
ANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9594
BRD-K92749855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19282
serous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212586
BRD-K17232330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48704
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41529
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5655
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830613
Poisoning	CTD Gene-Disease Associations	1.0	1.68527
Dinoprost Tromethamine	DrugBank Drug Targets	1.0	null
RUNX2-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8445
Perturb_13907_KD_UBE3A_SRP124518	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.3706
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42162
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67049
BRD-K95014129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03526
SNRK_overexpression_127_GSE30185	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.42006
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1536
TET1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00373795
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.921476
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.552
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0567
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.377738
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
Hypokalemia	CTD Gene-Disease Associations	1.0	1.61552
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.72497
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25776
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.39062
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.2112
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10997
BeWo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
EW-24	GDSC Cell Line Gene Expression Profiles	1.0	1.72792
FLYWCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98809
biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.784755
BRD-K24680618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8634
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44351
NCIH2052	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64237
Arthritis, Gouty	CTD Gene-Disease Associations	1.0	1.35242
Liothyronine	DrugBank Drug Targets	1.0	null
capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08413
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29284
subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.788964
Nephrogenic diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82772
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883132
DNAJC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41909
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	2.51272
Excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.87
nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.124125
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-TT-A6YO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.229532
BRD-K78902613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33627
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
BRD-K02361314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09315
BRD-K46619710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19537
BRD-K52017042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08625
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33838
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Valproic Acid	DrugBank Drug Targets	1.0	null
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.45089
ST8SIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43885
secretion	GeneRIF Biological Term Annotations	1.0	null
BRD-K33495825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87115
reveal	GeneRIF Biological Term Annotations	1.0	null
ECC12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04979
Mercuric Chloride	CTD Gene-Chemical Interactions	1.0	null
PMC12756533-mmc1.pdf-32-ZNF395_ZNF395	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30078
BRD-K36523261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05656
GSE164494_1_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Pleural Effusion	CTD Gene-Disease Associations	1.0	1.14438
topotecan	GeneRIF Biological Term Annotations	1.0	null
BRD-K64827406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43226
Perturb_16648_KO_Tardbp_SRP201975	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.65173
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56181
Renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.103
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97165
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50344
genome	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bile secretion	KEGG Pathways 2026	1.0	null
anionic	GeneRIF Biological Term Annotations	1.0	null
BRD-K40814141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82059
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.481
Cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8214
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60446
GSE101239_4_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Purpura	CTD Gene-Disease Associations	1.0	1.29225
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52288
BRD-K61185334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45641
coexpressed	GeneRIF Biological Term Annotations	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16404
SLR26	DepMap CRISPR Gene Dependency	1.0	3.1558
FIGNL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
mania	GWASdb SNP-Phenotype Associations	1.0	0.473207
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48832
Bonemarrow	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.15388
hsa-miR-3616-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.1111
effect	GeneRIF Biological Term Annotations	1.0	null
Hyperammonemia	CTD Gene-Disease Associations	1.0	1.17893
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.891682
PRKCZ	Hub Proteins Protein-Protein Interactions	1.0	null
Influenza A	DisGeNET Gene-Disease Associations	1.0	null
BRD-K62599086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54403
Hemolysis	CTD Gene-Disease Associations	1.0	1.47115
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0371
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
drugs	GeneRIF Biological Term Annotations	1.0	null
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_10_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
ALDH5A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13697
H3K27ac_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.764882
Balkan nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AH-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49108064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1676
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mdck cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.845805
DLX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48473
BRD-K90027990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25258
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52633
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20675
MYB	ENCODE Transcription Factor Targets	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282483
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19464
Hepa-RG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
CRCGN015_MCF10A.WT.HP_24H:E11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3127
BRD-K26233698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23477
BRD-K08110534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39554
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.89
Famotidine	DrugBank Drug Targets	1.0	null
BRD-K39020351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00533
Dyspepsia	CTD Gene-Disease Associations	1.0	1.17794
Hepatitis C	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35442
BRD-K11636255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26937
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	1.47509
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.956
Intracellular immature spore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.745
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85491
BRD-K64520484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29449
IFNAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89248
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.696989
HIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31477
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48789
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956001
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I7-06A-22R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.551695
CRCGN015_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0251
KDM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67365
renal	GeneRIF Biological Term Annotations	1.0	null
glutamate-cysteine ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.752
response to nitrogen compound	GO Biological Process Annotations 2015	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.05
Vascular endothelial glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
ureteral obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.462394
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.898
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05802
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.857
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.643
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.525
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10853
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058087
Perturb_10261_KO_Esrrg_SRP119935	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.72551
Colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23461
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.945
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
MLEC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60826
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09308
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12891
11493696-TableS3	GeneSigDB Published Gene Signatures	1.0	null
mean	GeneRIF Biological Term Annotations	1.0	null
CCDC186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6349
PMC9396374-Table_5.XLSX-Table_S5-AR_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
MUTZ5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35081
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876393
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC12A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82785
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01338
mercuric oxide	CTD Gene-Chemical Interactions	1.0	null
GSE102870_5_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uric Acid	CTD Gene-Chemical Interactions	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.17
TSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2025
Chorionic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
SUPT4H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94423
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.244
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.661523
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62017257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33599
PMC12271188-Table_3.XLSX-total-RELA_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
MELHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49116
BRD-K92378241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.42466
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4270	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K65829768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06064
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.009
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
ML1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54772
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0245
Ketoprofen	DrugBank Drug Targets	1.0	null
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32828
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal renal/urinary system physiology	MPO Gene-Phenotype Associations	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6515
TEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70206
choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218186
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0597
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03855
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.34053
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
Myocardial Ischemia	CTD Gene-Disease Associations	1.0	1.05972
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96379
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
EPAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03426
NHBE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.358551
OE21	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45275
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55876
ZIC2_01_121	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.35656
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hoat1	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2436
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute lymphoblastic leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6042
Neutropenia	CTD Gene-Disease Associations	1.0	1.65204
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60589
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6053
PRPF38A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90368
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8381
CRCGN015_MCF10A.TP53.M_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3832
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.350372
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9767
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.128891
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.713
HUH6	DepMap CRISPR Gene Dependency	1.0	2.13056
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.23
BRD-K75915595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03306
collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23781
BRD-K51153795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65816
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15940717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24674
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92484282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19211
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Medial geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
FLUORESCEIN	DGIdb Drug Targets 2026	1.0	1.65412
SHPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01081
FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3014
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Cefotiam	CTD Gene-Chemical Interactions	1.0	null
ZNF620	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93679
kynurenic	GeneRIF Biological Term Annotations	1.0	null
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56982
NINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71567
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.921205
tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383509
GSE244072_10_v_7_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24915
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.58983
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51342
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21062
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12891
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.949098
BRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37721
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15328
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
Rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.744
p-Aminohippuric Acid	CTD Gene-Chemical Interactions	1.0	null
Benzylpenicillin	DrugBank Drug Targets	1.0	null
L-1236	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Homovanillic Acid	CTD Gene-Chemical Interactions	1.0	null
ZNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19706
Tetracycline	DrugBank Drug Targets	1.0	null
BRD-K82508779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56281
GNRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66869
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperemia	CTD Gene-Disease Associations	1.0	1.28395
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46359
COPD - Chronic obstructive pulmonary disease_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE475	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.23199
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.438739
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905909
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23657
Ureteral obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
BRD-A81879813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5221
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.42229
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.5
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05035
Arachnoid mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.405
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
endometrial stromal sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312102
Tetraethylammonium	DrugBank Drug Targets	1.0	null
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
GSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20658
PMC4496795-srep12063-s2.xls-STAT1_subnetwork-Gene_symbol_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
brain infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.289744
layer 3 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36364
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
kidney	HPA Tissue Protein Expression Profiles	1.0	1.71758
GSE198054,GSE198057_0_v_1_csf1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50203
SHMAC5	DepMap CRISPR Gene Dependency	1.0	4.19109
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14752
HAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40105
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
SV2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45984
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.04177
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04658
DNAJC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51474
retinopathy of prematurity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.239799
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3671
Saxagliptin	DrugBank Drug Targets	1.0	null
rs10792367	GeneRIF Biological Term Annotations	1.0	null
Peritonitis	CTD Gene-Disease Associations	1.0	1.07518
UPCISCC131	DepMap CRISPR Gene Dependency	1.0	4.21974
HFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70783
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.966
Acetylcysteine	CTD Gene-Chemical Interactions	1.0	null
FOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47277
fluoxetine_mus musculus_gpl1261_gse35761	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ewing's sarcoma_Renal Tissue_GSE1822	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.41934
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31311
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5741
RALGAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83676
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.440658
Acute leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHH1	CCLE Cell Line Gene Expression Profiles	1.0	1.40386
MCCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08087
BRD-K01798544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11715
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33153
ISL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3227
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04962
FLI1	ChEA Transcription Factor Targets	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAB29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51244
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55639
MEIS1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAL-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIGLEC14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048704
MEIS1	ChEA Transcription Factor Targets	1.0	null
E2A_KO_GSE43224_679_mouse_DN2 cells from WT and E2A-deficient murine fetal thymi	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
Cimetidine	DrugBank Drug Targets	1.0	null
GSE121246_1_v_0_stat5b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRATOSARTAN	DGIdb Drug Targets 2026	1.0	0.827062
5-methoxyindoleacetic acid	CTD Gene-Chemical Interactions	1.0	null
order	GeneRIF Biological Term Annotations	1.0	null
Nasopharyngitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Insulin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6427
SNU840	DepMap CRISPR Gene Dependency	1.0	3.48566
Valaciclovir	DrugBank Drug Targets	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
14555994-Table1	GeneSigDB Published Gene Signatures	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06271
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69648
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095113
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22144
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94132
FAM118B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32706
NPIPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50428
MDCK-MDR1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.497
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905909
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pneumonia	CTD Gene-Disease Associations	1.0	1.37874
BRD-K67146164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24461
BRD-K11003742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53779
AMOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68714
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.971
Glioblastoma	CTD Gene-Disease Associations	1.0	1.09262
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90874
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
OCIM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59298
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.226155
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16409
PIP4P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7264
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
myclobutanil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04287
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.117
Methotrexate	CTD Gene-Chemical Interactions	1.0	null
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50246
NCI H23	BioGPS Cell Line Gene Expression Profiles	1.0	1.5381
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06972
STX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58748
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cyclic Adenosine Monophosphate	DrugBank Drug Targets	1.0	null
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oat4	GeneRIF Biological Term Annotations	1.0	null
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Ouabain	DrugBank Drug Targets	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.087
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.221
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50124
BRD-K85110576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35452
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43989
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27823
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.519
Brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.913
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4784386__F5	PFOCR Pathway Figure Associations 2023	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3373
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
HS2ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69716
anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
s2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387781
TAL1	ENCODE Transcription Factor Targets	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
layer 5 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77482
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30709
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0503
Cilastatin	DrugBank Drug Targets	1.0	null
slc22a8	GeneRIF Biological Term Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.958875
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01066
EP300	ENCODE Transcription Factor Targets	1.0	null
abnormal urine uric acid level	MPO Gene-Phenotype Associations	1.0	null
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
Reperfusion Injury	CTD Gene-Disease Associations	1.0	1.07163
Gastrointestinal Hemorrhage	CTD Gene-Disease Associations	1.0	1.68019
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.131642
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hybridoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183551
Liver Failure	CTD Gene-Disease Associations	1.0	1.52889
Leukopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.413
BRD-K36643302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02282
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.86727
BRD-K78003637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37501
TAF6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.286
BRD-K07697589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0882
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3962
mate1	GeneRIF Biological Term Annotations	1.0	null
Blood coagulation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
Blood platelet disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34669
Myocardial Ischemia	DisGeNET Gene-Disease Associations	1.0	null
Ribose phosphate diphosphokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.534
Arrhythmias, Cardiac	CTD Gene-Disease Associations	1.0	1.12872
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A99445203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14293
BRD-K09721123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27886
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.185
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.96831
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKNDZ	DepMap CRISPR Gene Dependency	1.0	3.3981
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41049
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
occluding junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.381969
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22646
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14222
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.570021
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
CCDC115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20875
sulforafan	CTD Gene-Chemical Interactions	1.0	null
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13511
cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.872462
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57404
OV7	CCLE Cell Line Gene CNV Profiles	-1.0	-2.71965
SCS214	DepMap CRISPR Gene Dependency	1.0	2.04578
NTPCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12607
CTSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03232
Novobiocin	DrugBank Drug Targets	1.0	null
BRD-A54490075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11751
z85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
RBFOX2_02_101	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.45943
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2627
BRD-K28995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06885
KMS20	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8044
Disseminated Intravascular Coagulation	CTD Gene-Disease Associations	1.0	1.20394
lymphoma	GeneRIF Biological Term Annotations	1.0	null
basolateral plasma membrane	GO Cellular Component Annotations 2015	1.0	null
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYO19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35325
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16404
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054192
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7434
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.974149
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
ZIDOVUDINE	DGIdb Drug Targets 2026	1.0	0.245056
ZFYVE16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34811
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827388
KY821	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50951
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9328
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.167
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Postoperative Complications	CTD Gene-Disease Associations	1.0	1.05015
Nephritis	CTD Gene-Disease Associations	1.0	1.22177
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.026
mate2k	GeneRIF Biological Term Annotations	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05963
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
DTX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20979
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12385
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1563
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085891
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26391
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sites	GeneRIF Biological Term Annotations	1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47182
ZNF879	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26692
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A57474391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44341
HEXA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76108
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6772
SF295	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69476
HK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
tiotropium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66458
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	59.7336
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45318
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIR122_Antisense Inhibition_GDS1729_759_mouse_Livers (from C57BL/6 adult males)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952961
contribute	GeneRIF Biological Term Annotations	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18318
OVISE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51607
GATA2	ENCODE Transcription Factor Targets	1.0	null
LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.51902
HUH7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45488
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
KG1	CCLE Cell Line Gene CNV Profiles	1.0	1.49169
decreased urine uric acid level	MGI Mouse Phenotype Associations 2023	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049079
lymphocytic	GeneRIF Biological Term Annotations	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skin	GTEx Tissue Gene Expression Profiles	-1.0	-0.917674
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Vomiting	CTD Gene-Disease Associations	1.0	1.42723
BRD-K65184008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11145
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2747
PALB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3664
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04209
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054209
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84631
PMC10204296-13578_2023_1034_MOESM16_ESM.xlsx-Black-ZNF671_ZNF671	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12891
rosuvastatin	GeneRIF Biological Term Annotations	1.0	null
BRD-K10684867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42128
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18501
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96355
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
MNDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08121
MYB_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24458
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GM-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1215
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26899
NPPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78521
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.49135
ORMDL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46607
BRD-A91461229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34824
accumbens nucleus, shell domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84725
ZHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77541
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32754
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86404
single-organism localization	GO Biological Process Annotations 2015	1.0	null
MAPK6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00349582
BRD-K02159857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00783
Liver Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
PITHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5925
all	GWASdb SNP-Phenotype Associations	1.0	0.030807
Perturb_10323_KO_MYC/Setd2_SRP310502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.9928
BRD-K44427106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29007
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.944
ZNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33804
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hepatitis B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.393
Gastritis	CTD Gene-Disease Associations	1.0	1.65113
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28613
Perturb_10293_KO_Ctrp1_SRP187060	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.18516
BRD-K88756517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01528
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.753
GSE123372,GSE123373_10_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46968
SCN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1155
Cefacetrile	DrugBank Drug Targets	1.0	null
ALEXANDERCELLS	CCLE Cell Line Gene Expression Profiles	1.0	1.59419
perfluoro-n-heptanoic acid	CTD Gene-Chemical Interactions	1.0	null
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3123
Vaginal epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52072
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044252
SEMA6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54683
icosanoid transport	GO Biological Process Annotations 2025	1.0	null
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	2.43348
BRD-K61158263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21451
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Constipation	CTD Gene-Disease Associations	1.0	1.02971
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.676
Mitochondrial processing peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.754
NCCRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95105
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.573
TCF12	ENCODE Transcription Factor Targets	1.0	null
solute:inorganic anion antiporter activity	GO Molecular Function Annotations 2023	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
extracellular vesicular exosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.1921
Proximal tubular cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
lower	GeneRIF Biological Term Annotations	1.0	null
brain capillary endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.940925
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Primary visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01291
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28552
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19436
Perturb_13289_OE_Axin1_SRP070058	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876393
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09757
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89607
Pain	CTD Gene-Disease Associations	1.0	2.0463
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04383
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0478
Tachycardia	CTD Gene-Disease Associations	1.0	1.12219
prostaglandin transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
GSE217363_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endothelial cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83299
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
BRD-K33842318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26031
CRCGN016_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11805
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42688
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
BRD-K65432867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03312
choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.52473
Inappropriate ADH Syndrome	CTD Gene-Disease Associations	1.0	1.11606
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9584
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE164494_1_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2201
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49058
PANC0813	CCLE Cell Line Gene CNV Profiles	1.0	1.53841
cell part	GO Cellular Component Annotations 2015	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55058
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86674
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	2.02743
Erythema	CTD Gene-Disease Associations	1.0	1.09998
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.86746
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29903
BRD-K15174326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83028
Urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.912
GSE229978_4_v_7_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K45022385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20787
abnormal urine organic anion level	MPO Gene-Phenotype Associations	1.0	null
CAB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76903
well	GeneRIF Biological Term Annotations	1.0	null
CHD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69641
Glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
chronic	GeneRIF Biological Term Annotations	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5246
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65032
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65045
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4204
Lens cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55886
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30624
Capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.508
vascular transport	GO Biological Process Annotations 2023	1.0	null
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
hsa-miR-4264	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dysuria	CTD Gene-Disease Associations	1.0	1.04757
BRD-K55665639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28629
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
accounted	GeneRIF Biological Term Annotations	1.0	null
single	GeneRIF Biological Term Annotations	1.0	null
BRD-A52749901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61022
BRD-K23831817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40346
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
Bradycardia	CTD Gene-Disease Associations	1.0	1.47012
HPD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00340443
MAFK	ENCODE Transcription Factor Targets	1.0	null
BRD-K52552873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18816
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.374
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09917
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64367
Renal proximal tubule epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.144
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
RVH421	DepMap CRISPR Gene Dependency	1.0	2.37817
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
LPAR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17642
ODF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02435
acid	GeneRIF Biological Term Annotations	1.0	null
BRD-K95153342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03803
Coma	CTD Gene-Disease Associations	1.0	1.60617
organelle	GO Cellular Component Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1188
NYAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54851
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03226
promoter	GeneRIF Biological Term Annotations	1.0	null
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00158
milker's nodule	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54648
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MM-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNRNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29038
PANTOPRAZOLE SODIUM	DGIdb Drug Targets 2026	1.0	0.827062
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19707
prostaglandin transport	GO Biological Process Annotations 2023	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05387
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A728-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.524
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49222
BRD-K15800236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56873
betweenindividual	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
ATG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39016
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
PMC7293310-41467_2020_16179_MOESM8_ESM.xlsx-Table_S9_GATA1_WT24h_vs_SET24-Unnamed_9_GATA1	Rummagene Transcription Factor Associations 2026	1.0	null
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38681
resveratrol	CTD Gene-Chemical Interactions	1.0	null
Pancreatic Neoplasms	CTD Gene-Disease Associations	1.0	1.31476
into	GeneRIF Biological Term Annotations	1.0	null
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40786
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.16521
UBE2Q2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40836
determines	GeneRIF Biological Term Annotations	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
unlikely	GeneRIF Biological Term Annotations	1.0	null
Lethargy	CTD Gene-Disease Associations	1.0	1.03864
OK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
protein kinase c binding	GO Molecular Function Annotations 2015	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48016
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34031
Supportive connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.711
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
anion	GeneRIF Biological Term Annotations	1.0	null
RAB4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60698
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39691
excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
Glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.044
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.44687
Perturb_15794_KO_S1pr3/S1pr1/S1pr2_SRP234700	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.64048
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35126
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48207
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	2.19534
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66698
COV318	DepMap CRISPR Gene Dependency	1.0	11.6273
Salicylic acid	DrugBank Drug Targets	1.0	null
ZNF843	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1833
highaffinity	GeneRIF Biological Term Annotations	1.0	null
NRK-52E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.442
BRD-K62318087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0515
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19327
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cefalotin	DrugBank Drug Targets	1.0	null
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86424
Seizures	CTD Gene-Disease Associations	1.0	2.08416
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
did	GeneRIF Biological Term Annotations	1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14294
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.380045
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58449
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48758
SCARB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89102
MALME 3M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.50047
SMAD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87791
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.227
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.623
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07114
CRCGN015_HEPG2_48H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1728
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
BRD-K49473928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15106
hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.389289
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Leucovorin	CTD Gene-Chemical Interactions	1.0	null
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51209
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.483604
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.434
CRCGN017_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5313
common	GeneRIF Biological Term Annotations	1.0	null
Hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.137
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.888
SW962	GDSC Cell Line Gene Expression Profiles	1.0	1.6603
hybridoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25457
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.68262
Hepatitis	CTD Gene-Disease Associations	1.0	1.86672
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.165
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21792
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97114
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32761
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.976547
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18362
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12271188-Table_3.XLSX-CTD-RELA_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00644
Pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.074
BRD-K21789048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01218
BRD-A03940741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2641
Liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71094
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
furan	CTD Gene-Chemical Interactions	1.0	null
BRD-K90887068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33798
methotrexate	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cystitis	CTD Gene-Disease Associations	1.0	1.59357
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NPT520-34	DGIdb Drug Targets 2026	1.0	3.30825
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
improve	GeneRIF Biological Term Annotations	1.0	null
POLR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7805
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.700722
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10853
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.4899
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04402
CAVIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05812
basolateral plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	2.14988
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10292_OE_Ccne1_SRP185695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.88031
plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126617
Antipodal site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
regulatory	GeneRIF Biological Term Annotations	1.0	null
K562	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37255
GATA1	ENCODE Transcription Factor Targets	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.716651
BRD-K78386654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08677
Lung adenocarcinoma_LUAD_TCGA-44-2659-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57756744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19062
ZNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6389
hsa-miR-2116	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Exanthema	CTD Gene-Disease Associations	1.0	2.00647
brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.850665
Anorexia	CTD Gene-Disease Associations	1.0	1.38752
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067783
HO-1-N-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5805
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.23042
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12452
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59697
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anoxia	CTD Gene-Disease Associations	1.0	1.04574
SBC-5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K21139023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49745
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69191
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34846
Dinoprostone	CTD Gene-Chemical Interactions	1.0	null
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78782
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44918
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84991
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80685
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01401
RECQL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85904
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042371
Glutaric Acid	DrugBank Drug Targets	1.0	null
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urticaria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.282225
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040284
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07253
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
epithelial	GeneRIF Biological Term Annotations	1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.58255
CEP76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53425
Glioma	CTD Gene-Disease Associations	1.0	1.05015
Ibuprofen	DrugBank Drug Targets	1.0	null
ZNF160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0321
OXACILLIN	DGIdb Drug Targets 2026	1.0	6.6165
MAP3K7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0046203
BRD-K68257831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40913
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
Bilirubin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36372
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
IFT46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96252
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65725
RUNDC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50954
anion:anion antiporter activity	GO Molecular Function Annotations 2015	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.68401
GSE184902_3_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prospore membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
BRD-K14098658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47044
Fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.647
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
endometrial stromal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.309928
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75712
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.985886
WM983B	DepMap CRISPR Gene Dependency	1.0	3.11775
Jaundice, Obstructive	CTD Gene-Disease Associations	1.0	1.09436
BRD-A06149038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53691
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43878
CRCGN008_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06965
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.202
BRD-K66470464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07099
BRD-K14245433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.776
BRD-K75260889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21304
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glucuronides	GeneRIF Biological Term Annotations	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7576
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099082
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4509
KDM5A	ENCODE Transcription Factor Targets	1.0	null
nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435289
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.183
influence	GeneRIF Biological Term Annotations	1.0	null
cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K40001806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03312
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98469
pemetrexed	GeneRIF Biological Term Annotations	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
tarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.173079
Cefazolin	DrugBank Drug Targets	1.0	null
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.883
Probenecid	CTD Gene-Chemical Interactions	1.0	null
anion transport	GO Biological Process Annotations 2015	1.0	null
KIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5208
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5808
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27925
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.23
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05174
Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.354422
hydroxyl	GeneRIF Biological Term Annotations	1.0	null
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07176
BRD-K44458042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14774
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Epithelial lining fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
pioglitazone_mus musculus_gpl1261_gds4413	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13596
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60152
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04185
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.679433
TGBC24TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
transporters	GeneRIF Biological Term Annotations	1.0	null
1-Methyl-4-phenylpyridinium	CTD Gene-Chemical Interactions	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
496100468_PCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.2569
OTULIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99736
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61798
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04053
BRD-K83603369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.91889
NFE2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01562
brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.949236
TERB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19408
BICR22	DepMap CRISPR Gene Dependency	1.0	3.06111
CESS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18444
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17536
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905909
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49769
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.42193
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4282
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.10077
NCI-H2110	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cyclic AMP	CTD Gene-Chemical Interactions	1.0	null
hsa-miR-499-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Hematuria	CTD Gene-Disease Associations	1.0	1.79216
lateropallial prepiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12526
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.970371
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041859
BRD-K31820800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87612
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.71627
acute	GeneRIF Biological Term Annotations	1.0	null
GSE182640_1_v_0_postn_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K80232129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69071
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23508
fatty acid transport	GO Biological Process Annotations 2023	1.0	null
Esophagitis	CTD Gene-Disease Associations	1.0	1.05648
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ciprofloxacin ADME	Reactome Pathways 2024	1.0	null
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34581
Necrosis	CTD Gene-Disease Associations	1.0	2.46138
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Enalapril	DrugBank Drug Targets	1.0	null
Visceral fat	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
BRD-K80336250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25564
BRD-K89338336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.48272
Carnitine	CTD Gene-Chemical Interactions	1.0	null
organic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.208579
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.83895
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.37774
KU-19-19	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68933
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16637
CORO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23119
EJM	DepMap CRISPR Gene Dependency	1.0	9.33042
obstructive jaundice	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.872872
BRD-K68408385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16623
BRD-K98625375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44387
EPLC272H	DepMap CRISPR Gene Dependency	1.0	3.91611
Cefaclor	CTD Gene-Chemical Interactions	1.0	null
RPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66306
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96685
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.819
hsa-miR-4436b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
DCAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.0
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87326
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.473207
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 2	HuBMAP ASCT+B Annotations	1.0	null
Brain capillary endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.146
response to methotrexate	GO Biological Process Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
mrp2	GeneRIF Biological Term Annotations	1.0	null
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Aortic smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
GSS	CCLE Cell Line Gene CNV Profiles	1.0	1.42974
Anterior cingulate area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17729
HRPT-related hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
Fatty Liver	DisGeNET Gene-Disease Associations	1.0	null
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22346
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42107
Leukocyte disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.109775
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TTLL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.23845
superficial stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07104
NCIH1437	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38312
Vasospasm, Intracranial	CTD Gene-Disease Associations	1.0	1.06479
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
bortezomib	CTD Gene-Chemical Interactions	1.0	null
THAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70616
Hypercholesterolemia	CTD Gene-Disease Associations	1.0	1.07093
BRD-K75620843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13259
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
KLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04204
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07771
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.26868
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96225
BRD-K42679315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.748
Perturb_15790_KO_Il19_SRP356176	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.76694
KIAA1191	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.27531
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cefoselis	CTD Gene-Chemical Interactions	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30023
CCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09899
Perturb_10322_KO_MYC_SRP310502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.66182
Coronary Vasospasm	CTD Gene-Disease Associations	1.0	1.1014
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86232
KIF3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80641
changes	GeneRIF Biological Term Annotations	1.0	null
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Drug ADME	Reactome Pathways 2024	1.0	null
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
GK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43835
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36055
TP53INP2_OE_GDS5054_545_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27819
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992826
bronchoalveolar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091022
Dinoprostone	DrugBank Drug Targets	1.0	null
transport across blood-brain barrier	GO Biological Process Annotations 2023	1.0	null
TCF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81716
Stomach Neoplasms	CTD Gene-Disease Associations	1.0	1.19246
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23836
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.941
Estradiol	DrugBank Drug Targets	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4817
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.084
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.83093
E2A_KO_GDS5084_401_mouse_DN2 thymocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
layer 4 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52741
Urticaria	CTD Gene-Disease Associations	1.0	1.7074
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.314
BRD-A71666580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30985
purine-pyrimidine metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82246
Intestinal wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
BRD-K80413110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15438
Obesity	DisGeNET Gene-Disease Associations	1.0	null
Oliguria	CTD Gene-Disease Associations	1.0	1.50574
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.11011
Dehydration	CTD Gene-Disease Associations	1.0	1.0734
hsa-miR-3179	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Liver Diseases	CTD Gene-Disease Associations	1.0	2.27209
Leukopenia	CTD Gene-Disease Associations	1.0	1.71973
transport	GO Biological Process Annotations 2015	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.87828
Perturb_563_KD_MYCN_SRP158473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.71091
abnormality of connective tissue	GWASdb SNP-Phenotype Associations	1.0	0.406588
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77096
BRD-K42799692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05044
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71548
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	2.04917
SALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06217
response to organonitrogen compound	GO Biological Process Annotations 2015	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.752716
Major facilitator superfamily domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
BRD-K22471908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08371
Neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952961
BRD-A24369193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84837
Embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.046
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GS-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5741-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.22263
Indocyanine Green	CTD Gene-Chemical Interactions	1.0	null
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408212
COR-L279	GDSC Cell Line Gene Expression Profiles	1.0	1.50839
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.663
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8752
Zidovudine	DrugBank Drug Targets	1.0	null
CAPZA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.75392
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
Obstructive nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
Brain Edema	CTD Gene-Disease Associations	1.0	1.19412
Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.58708
secretory	GeneRIF Biological Term Annotations	1.0	null
SFXN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97555
Transport of bile salts and organic acids, metal ions and amine compounds	Reactome Pathways 2024	1.0	null
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36962
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4827
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1582
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acute kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.137476
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58896
BRD-K46313713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7761
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77019
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.185
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2267
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
20035825-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.946806
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26051
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
BRD-K69147598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24237
ALKBH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567925
BRD-K12230293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67334
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
Caprylic acid	DrugBank Drug Targets	1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.142089
DDIT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75242
DOV13	DepMap CRISPR Gene Dependency	1.0	2.39555
BRD-K76885311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60273
SYNE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73776
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
rats	GeneRIF Biological Term Annotations	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040355
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MRPL58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54935
INTS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0479
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057395
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09689
obesity	GWASdb SNP-Disease Associations	1.0	1.04846
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.419
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.464
FAM136A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16586
UBR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81305
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hybridoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
Dabrafenib	DrugBank Drug Targets	1.0	null
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218186
GATA3-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Acidosis	CTD Gene-Disease Associations	1.0	1.19737
preosteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130903
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Organic cation transport protein	InterPro Predicted Protein Domain Annotations	1.0	null
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5563
fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234878
estrone sulfate	CTD Gene-Chemical Interactions	1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	2.34636
Nephrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88386
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03041
GSE212772_0_v_1_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.09503
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18427
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44748
capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.980217
ascospore-type prospore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
Gentamicins	CTD Gene-Chemical Interactions	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
CD320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99887
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.244
Dizziness	CTD Gene-Disease Associations	1.0	1.15593
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.046
membrane	GO Cellular Component Annotations 2015	1.0	null
CDCA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67777
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51592
Heart Arrest	CTD Gene-Disease Associations	1.0	1.29812
BRD-K86893953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00366
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.22994
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HI-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.975501
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057226
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66116
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76857
PTK7_KD_GSE50138_674_human_H1299	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.930843
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	1.0	1.20792
Gastrointestinal Diseases	CTD Gene-Disease Associations	1.0	2.03278
vascular skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175146
Vitamin D Deficiency	DisGeNET Gene-Disease Associations	1.0	null
perfluorodecanoic acid	CTD Gene-Chemical Interactions	1.0	null
BRD-K06956443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82888
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07634
BRD-K79861274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26589
C32	DepMap CRISPR Gene Dependency	1.0	2.36258
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77053
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302838
Muscular Diseases	CTD Gene-Disease Associations	1.0	1.47813
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12383
GSE130401_6_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.129
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.11336
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.93573
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6216
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21491
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57187
Sepsis	CTD Gene-Disease Associations	1.0	1.65249
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046122
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19356
Digoxin	DrugBank Drug Targets	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056194
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30499
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
Lung Diseases	CTD Gene-Disease Associations	1.0	1.55304
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.38609
genetic	GeneRIF Biological Term Annotations	1.0	null
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.80563
CDC42EP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30567
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
Bhktk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.343473
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21062
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5139
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24847
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.781543
PAX6-23342162-BETA-FORBRAIN-LENS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.534
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Phenylbutazone	DrugBank Drug Targets	1.0	null
BRD-K77845452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42885
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.53208
ZNF385C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77852
hydrochlorothiazide	GeneRIF Biological Term Annotations	1.0	null
GSE151494_10_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61247793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30314
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36948
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.315
Brain microvessel endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.489
confirmed	GeneRIF Biological Term Annotations	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04929
Coronary Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02438
Anuria	CTD Gene-Disease Associations	1.0	1.74561
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870316
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61478
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A77P-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transporter	GeneRIF Biological Term Annotations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054979
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3315
Enalapril	CTD Gene-Chemical Interactions	1.0	null
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.290462
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12169
Endocervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
XXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61614
Mesangial Proliferative Glomerulonephritis	DisGeNET Gene-Disease Associations	1.0	null
Pericardial Effusion	CTD Gene-Disease Associations	1.0	1.11911
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
taken	GeneRIF Biological Term Annotations	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inhibition	GeneRIF Biological Term Annotations	1.0	null
Renal Insufficiency	CTD Gene-Disease Associations	1.0	2.19534
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57525
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIAA0753	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38255
Nascent polypeptide-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.322
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACOT13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7817
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36372
ATM_KD_GSE54268_663_human_MCF-10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75299
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20407
hnf1alpha	GeneRIF Biological Term Annotations	1.0	null
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18507
SF-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.266
endometrial cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.128746
FUT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05464
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF268	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03187
hsa-miR-4432	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18213
alteration	GeneRIF Biological Term Annotations	1.0	null
BAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69707
BRD-K33775409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06824
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0422
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EM-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PREP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98091
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.546
Nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.034
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93502
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.706
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
SW579	DepMap CRISPR Gene Dependency	1.0	2.77026
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
BRD-K84846130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27223
Kidney Diseases	CTD Gene-Disease Associations	1.0	2.43943
ZNF800	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92847
Perturb_4468_KO_Cnr1_SRP346447	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.67451
SYCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13939
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.121257
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.508
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39079
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.16863
Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16404
inhibited	GeneRIF Biological Term Annotations	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.80567
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5309
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83096
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.94338
OVTOKO	DepMap CRISPR Gene Dependency	1.0	4.25712
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02526
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.398962
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3R3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
onset	GeneRIF Biological Term Annotations	1.0	null
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065296
Nephrotic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.166
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K46994278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26081
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.100789
inorganic anion transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K53931904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47088
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75164441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61893
SRY	ChEA Transcription Factor Targets	1.0	null
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72665
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.991407
JBP 485	CTD Gene-Chemical Interactions	1.0	null
Pancreatitis	CTD Gene-Disease Associations	1.0	1.24433
ZNF479	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9709
ion transport	GO Biological Process Annotations 2015	1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57161
affinity	GeneRIF Biological Term Annotations	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6429
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Hepatitis	DisGeNET Gene-Disease Associations	1.0	null
Microvessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.489
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100370_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58836
Basolateral plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
ZSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79286
BRD-K38431962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25622
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Dubin-Johnson syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HEK-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.048
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6005
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33537
Pain, Postoperative	CTD Gene-Disease Associations	1.0	1.37705
Neurologic Manifestations	CTD Gene-Disease Associations	1.0	1.24181
Cephalexin	DrugBank Drug Targets	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50162
Aminohippurate	DrugBank Drug Targets	1.0	null
Persistent fetal circulation syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
DNAJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73808
BRD-A75087829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0775
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.947
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.674
BRD-K95768123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50542
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54717
Arachnoid trabecula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
Mitochondrial inner membrane peptidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.466
STK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80056
BRD-K17062413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47044
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13829
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40137
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.967
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41125
SIPA1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62621
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36642
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CEFOTAXIME SODIUM	DGIdb Drug Targets 2026	1.0	1.10275
Meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
BRD-K08881846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93165
Tuberculosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Ceftriaxone	DrugBank Drug Targets	1.0	null
Microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.413
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82469
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.58255
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91306
Anemia, Aplastic	CTD Gene-Disease Associations	1.0	1.24181
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.91167
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25832
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08654
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31017
BRD-K03057797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47913
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.031
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
dehydroepiandrosterone sulfate	DrugBank Drug Targets	1.0	null
Fever	CTD Gene-Disease Associations	1.0	1.93307
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.26359
Parathyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66828
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2
diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.120178
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430312
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62134
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.066871
polymorphism	GeneRIF Biological Term Annotations	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.620999
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71075
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.1426
DICLOXACILLIN	DGIdb Drug Targets 2026	1.0	3.30825
slc22a6	GeneRIF Biological Term Annotations	1.0	null
Median body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.841
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.17247
BRD-K27026825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36971
methylmalonic acidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.311377
hsa-miR-3545-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.06049
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.55253
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72441
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Hepatoma ascites cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.778
Conjugated Estrogens	DrugBank Drug Targets	1.0	null
BRD-K47366416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08212
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18467
Angioedema	CTD Gene-Disease Associations	1.0	1.46015
NFIC	ENCODE Transcription Factor Targets	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.89858
NFKBIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28047
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K32648402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04869
Testosterone	DrugBank Drug Targets	1.0	null
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1646
polymorphisms	GeneRIF Biological Term Annotations	1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Secondary hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.652
account	GeneRIF Biological Term Annotations	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
FMNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91399
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2692
mesangial proliferative glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.331756
Succinic acid	DrugBank Drug Targets	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056341
Tinnitus	CTD Gene-Disease Associations	1.0	1.11606
BRD-K44103530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00249
SUMO activating enzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.286519
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17703
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.969
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
RCOR1	ENCODE Transcription Factor Targets	1.0	null
tetracycline	GeneRIF Biological Term Annotations	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056895
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30068
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12432
llc-pk1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.928478
HCC2218	CCLE Cell Line Gene Expression Profiles	1.0	1.39819
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Furosemide	DrugBank Drug Targets	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24942
disposition	GeneRIF Biological Term Annotations	1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
Heart Failure	CTD Gene-Disease Associations	1.0	1.89698
TARBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57594
Acute Myeloid Leukemia_LAML_TCGA-AB-2901-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
vascular transport	GO Biological Process Annotations 2025	1.0	null
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.558
CRCGN012_HEPG2_24H:I21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21192
PPP5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29339
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38483
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.65417
meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09988
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2931
raises	GeneRIF Biological Term Annotations	1.0	null
Perturb_15846_KO_Adipor1_SRP339096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.75579
INTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
SKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44428
CHMP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95993
CALM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98828
CORL95	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59468
possible	GeneRIF Biological Term Annotations	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
Serum metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.8301
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.751271
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug Hypersensitivity	CTD Gene-Disease Associations	1.0	2.16089
factors	GeneRIF Biological Term Annotations	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
18537972-TableS3	GeneSigDB Published Gene Signatures	1.0	null
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26434
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.20622
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.035
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85926
hsa-miR-3202	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
BRD-K93980445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01729
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22915
496100296_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.57289
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
MEIOSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0112
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882203
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.929335
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Renal proximal tubule epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.271
GSE229978_4_v_2_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.58134
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09224
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bile canaliculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06101
drugdrug	GeneRIF Biological Term Annotations	1.0	null
GCLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54541
uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.111434
Drug Overdose	CTD Gene-Disease Associations	1.0	1.06406
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.96685
xanthurenic	GeneRIF Biological Term Annotations	1.0	null
METHOTREXATE	DGIdb Drug Targets 2026	1.0	0.116079
VK-2/E6E7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
Hepatic Encephalopathy	CTD Gene-Disease Associations	1.0	1.52591
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19544
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
BRD-A47109850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.62921
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89632
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.536625
ZBED2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4873
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KNS-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58597
Brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
Pneumonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
Ganciclovir	DrugBank Drug Targets	1.0	null
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37903
Vertigo	CTD Gene-Disease Associations	1.0	1.19412
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.302
plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234302
Placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.806
EFO27	DepMap CRISPR Gene Dependency	1.0	2.04879
BRD-K97217923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.3997
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6004
ZNF581	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80177
Renal outer medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77799
BRD-K01960204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16329
Anions	CTD Gene-Chemical Interactions	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061719
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.595
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.96013
GABPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17793
Kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.959
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
SNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39197
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.06144
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56502
Anterior cingulate area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70219
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88283
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22727
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SENP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76378
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77796
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50999
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06456
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100486_PCx_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89423
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	1.44553
oocytes	GeneRIF Biological Term Annotations	1.0	null
vascular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.322779
Lung adenocarcinoma_LUAD_TCGA-50-5946-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.526518
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21214
LTV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12868
Postsubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80218
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8876
Cimetidine	CTD Gene-Chemical Interactions	1.0	null
Arthritis, Rheumatoid	CTD Gene-Disease Associations	1.0	1.4633
tubules	GeneRIF Biological Term Annotations	1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.45131
Fatigue	CTD Gene-Disease Associations	1.0	1.4633
mrp4	GeneRIF Biological Term Annotations	1.0	null
HCC70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47195
MDCK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.008
Gilbert syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
Confusion	CTD Gene-Disease Associations	1.0	1.50323
BRD-K16570418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02195
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15717
ESCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39232
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.181
Thrombocytopenia	CTD Gene-Disease Associations	1.0	1.98712
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00059
PMC3734218__F1	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38864
BRD-K30812092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22636
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9006
GATA2_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12925
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0682
Methyltestosterone	DrugBank Drug Targets	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RRAGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7407
Pyelonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
DU4475	CCLE Cell Line Gene Expression Profiles	1.0	1.83283
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Proximal tubule transport	WikiPathways Pathways 2024	1.0	null
response to chemical	GO Biological Process Annotations 2015	1.0	null
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
ALG10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82563
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16019
SLC22A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02454
HCC95	DepMap CRISPR Gene Dependency	1.0	2.4075
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4712
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A06837695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19492
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
efflux	GeneRIF Biological Term Annotations	1.0	null
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.45989
FBXO22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6793
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13384
response to toxic substance	GO Biological Process Annotations 2015	1.0	null
Capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1524
imperatorin	CTD Gene-Chemical Interactions	1.0	null
Apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.877
Pruritus	CTD Gene-Disease Associations	1.0	1.6759
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09685
Fruit juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20011
H2AL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28258
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GT-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	3.3033
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.7189
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.162
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.84
Arthralgia	CTD Gene-Disease Associations	1.0	1.08055
DU145	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56162
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66246
angiotensin	GeneRIF Biological Term Annotations	1.0	null
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266069
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1585
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38184
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4033
SETBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15779
Posterior parietal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26302
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16503
KDM5B	ENCODE Transcription Factor Targets	1.0	null
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
caco-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459532
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
pou4f1_20376082_fetal_liver_lof_mouse_gpl1261_gds4042	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.705493
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60362
NIPSNAP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85007
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FARSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37292
Cefamandole	DrugBank Drug Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8385_KD_USP22_SRP213120	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.6009
Granuloma	CTD Gene-Disease Associations	1.0	1.19179
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Glutathione hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66298
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
GPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13528
hsa-miR-625	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.7832
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2777
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11861
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89123
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50738
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54225
Cisplatin	CTD Gene-Chemical Interactions	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8717
BRD-K37596331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33902
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
humans	GeneRIF Biological Term Annotations	1.0	null
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967339
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42077
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.917
Inner medullary collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-1909	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
Jugular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
ACIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91029
BRD-K70057550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36205
Brain cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78592
Renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.601
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030854
BRD-K35326556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01443
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MKN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51179
BRD-K65729053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91202
localization	GO Biological Process Annotations 2015	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
BRD-K94921631	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19275
MAP3K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04707
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09713
BRD-K52037352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08359
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.12616
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
TE5	CCLE Cell Line Gene CNV Profiles	1.0	2.2356
Allopurinol	CTD Gene-Chemical Interactions	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
Glutarates	CTD Gene-Chemical Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methylprednisolone_rattus norvegicus_gpl341_gds964	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055685
Colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.72
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14008
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
BBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83871
had	GeneRIF Biological Term Annotations	1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
nitrogen compound transport	GO Biological Process Annotations 2015	1.0	null
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13263
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903342
BRD-K96779993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93576
abnormal urine organic anion level	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00174
Anterior cingulate area, ventral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69941
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95108
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
PDLIM4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00657093
TIFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24654
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.906682
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Herpes zoster	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
A498	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56465
Ibuprofen	CTD Gene-Chemical Interactions	1.0	null
Colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.743
Staphylococcal Infections	CTD Gene-Disease Associations	1.0	1.56141
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
BRD-K11247495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1658
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0742
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
TLCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95651
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90711
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11997
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5667
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Degraded Cephaloridine	DrugBank Drug Targets	1.0	null
BRD-A92729194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01888
ZNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23078
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39762
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
probenecid	GeneRIF Biological Term Annotations	1.0	null
IgA glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6702
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
SRSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4571
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076788
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.118532
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62564
intergenic	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Choriocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.893885
Uremia	CTD Gene-Disease Associations	1.0	1.33701
cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.800626
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51137
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.66355
brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366381
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24748
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86791
PMC11184788-40164_2024_526_MOESM4_ESM.xls-MSC-EV_proteins-Unnamed_4_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K34447537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21735
mdck-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.603697
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.107504
GATA1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2336
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854294
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K96243955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11138
Serum uric acid levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2501
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04343
Adenoma	CTD Gene-Disease Associations	1.0	1.27502
3,4-dihydroxymandelic acid	CTD Gene-Chemical Interactions	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.881627
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38783
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.826681
EEF2KMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40706
BRD-K16626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00647
Nuclear aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
pharmacogenetic studies	GAD Gene-Disease Associations	1.0	null
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
Small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.968
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04962
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.053332
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09292
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26343
KU1919	CCLE Cell Line Gene CNV Profiles	1.0	2.49141
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19198
Eosinophilia	CTD Gene-Disease Associations	1.0	1.67761
BRD-K04108962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22025
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.392686
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
HARA	CCLE Cell Line Gene Expression Profiles	1.0	2.27142
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5708
Carbon Tetrachloride	CTD Gene-Chemical Interactions	1.0	null
DVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13396
Guanidine	DrugBank Drug Targets	1.0	null
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19463
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60618
antihypertensive	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28758
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.43197
NOMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	2.04979
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0124
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4359
BRD-A54769817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26504
layer 6 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59697
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.863662
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62529
CHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70207
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.454019
Probenecid	DrugBank Drug Targets	1.0	null
D-566MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47076
BB30-HNC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51415
BRD-K45928581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41647
Carcinoma, Squamous Cell	CTD Gene-Disease Associations	1.0	1.07696
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933931
DUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52515
Organic anion transport	Reactome Pathways 2014	1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.72146
Allopurinol	DrugBank Drug Targets	1.0	null
severe	GeneRIF Biological Term Annotations	1.0	null
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55374
BRD-K25161864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80736
BRD-A68797623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05278
BRD-K97943226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2646
Nephrotic Syndrome	CTD Gene-Disease Associations	1.0	1.22112
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
horsetail-astral microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.547
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5006
EXOSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90244
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.767
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.72467
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27865
BRD-K11242872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64873
Serous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260267
BRD-K91952416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33152
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07885
BRD-K30198800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47951
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.001
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133929
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.104
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC1B	DepMap CRISPR Gene Dependency	1.0	2.04968
STAT3	ENCODE Transcription Factor Targets	1.0	null
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
Famotidine	CTD Gene-Chemical Interactions	1.0	null
APBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64196
possibility	GeneRIF Biological Term Annotations	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63888
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24376
Sulfobromophthalein	CTD Gene-Chemical Interactions	1.0	null
NEIL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02442
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837882
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4048
Anterior cingulate area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12027
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Failure, Acute	CTD Gene-Disease Associations	1.0	1.79006
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
isoimperatorin	CTD Gene-Chemical Interactions	1.0	null
efficacy	GeneRIF Biological Term Annotations	1.0	null
RBM39_02_111	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.91886
BRD-K10638173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69348
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07307
Benzoic Acid	DrugBank Drug Targets	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.08393
Ranitidine	CTD Gene-Chemical Interactions	1.0	null
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34677
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Response to antidepressants in depression	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43237
protein1	GeneRIF Biological Term Annotations	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Colonic Neoplasms	CTD Gene-Disease Associations	1.0	1.68148
PKP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61512
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4305
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
kidney	GeneRIF Biological Term Annotations	1.0	null
BRD-K58955712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76226
SNU8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63231
gallbladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.087391
Bumetanide	DrugBank Drug Targets	1.0	null
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.708
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72503
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23581
BRD-K68665079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18634
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70795
HDAC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00417264
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57382977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41276
kidney	GTEx Tissue Gene Expression Profiles	1.0	2.18987
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5138
ANKRD46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52542
GSE206400_3_v_2_nusinersen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ceftizoxime	CTD Gene-Chemical Interactions	1.0	null
hsa-miR-18b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ISL1-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06837
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.4491
Drug-Induced Acute Liver Injury	DisGeNET Gene-Disease Associations	1.0	null
Esophageal Diseases	CTD Gene-Disease Associations	1.0	1.17366
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54368
PCTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42512
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney Neoplasms	CTD Gene-Disease Associations	1.0	1.21076
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5913
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.57522
CDKN2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18954
BRD-K24711162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31099
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1545
hnf1beta	GeneRIF Biological Term Annotations	1.0	null
oct2	GeneRIF Biological Term Annotations	1.0	null
Mercaptopurine	DrugBank Drug Targets	1.0	null
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82824
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2584
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Minocycline	DrugBank Drug Targets	1.0	null
Hyponatremia	CTD Gene-Disease Associations	1.0	1.04794
cholelithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199681
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13593
BRD-K93811242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01624
ZDHHC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11158
hexadecafluoro-nonanoic acid	CTD Gene-Chemical Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A199-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Basal part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.938
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73364700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54014
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9888
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67242
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49934
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
decreased urine uric acid level	MPO Gene-Phenotype Associations	1.0	null
BRD-K92176613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57766
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
sublayer 6a of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58621
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.43003
Jaundice	CTD Gene-Disease Associations	1.0	1.41856
KCNG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58748
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54357
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.79752
GNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76613
CILK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.82461
SUPT1	CCLE Cell Line Gene Expression Profiles	1.0	1.35464
Lung adenocarcinoma_LUAD_TCGA-78-7159-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9286
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
C11orf87	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98306
CREB1	ChEA Transcription Factor Targets	1.0	null
H2BC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10194
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
related	GeneRIF Biological Term Annotations	1.0	null
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81134
BRD-A52024592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70295
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.728
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7841
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065296
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3453
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.728389
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.588
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2567
SIMA	GDSC Cell Line Gene Expression Profiles	1.0	1.55233
BRD-K36923996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87281
CRCGN017_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8599
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.25214
RHBDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58372
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.163271
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.12737
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84285
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	103.453
Learning Disorders	CTD Gene-Disease Associations	1.0	1.68464
Rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.744
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
vascular smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.290295
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4664
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.861785
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.325187
BRD-K50677542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19329
WDR45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65374
DMRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83248
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MZ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52627
PHKG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4401
Liver Neoplasms	CTD Gene-Disease Associations	1.0	2.17438
Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5F1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48916
Visceral fat	GWAS Catalog SNP-Phenotype Associations	1.0	0.085234
BRD-K88200990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01557
Perturb_10326_KO_Shp1_SRP370028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.74645
BRD-K30173809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22652
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.38946
Cholates	CTD Gene-Chemical Interactions	1.0	null
CORL279	DepMap CRISPR Gene Dependency	1.0	3.86694
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
liddle syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.607714
BRD-K79561909	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23009
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61054
APELA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35762
sodium-phenylacetate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05734
five	GeneRIF Biological Term Annotations	1.0	null
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.81103
NXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36633
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93697
BRD-K02625776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14489
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 1	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067891
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2279
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868596
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
BRD-K83846772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14068
Thrombocytopenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Adenine phosphoribosyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31262
Erectile Dysfunction	CTD Gene-Disease Associations	1.0	1.18685
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49